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IMAIZUMI Tsutomu  今泉 勉

ORCIDConnect your ORCID iD *help
… Alternative Names

今泉 勉  イマイズミ ツトム

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Researcher Number 60148947
External Links
Affiliation (based on the past Project Information) *help 2009 – 2011: Kurume University, 医学部, 教授
2002 – 2005: 久留米大学, 医学部, 教授
1999 – 2000: 久留米大学, 医学部, 教授
1996 – 1997: 久留米大学, 医学部, 教授
1994: KURUME UNIVERSITY,MEDICINE,PROFESSOR & CHAIRMAN, 医学部, 教授 … More
1991 – 1993: 九州大学, 医学部, 講師
1988 – 1989: Kyushu University, Faculty of Medicine, Assistant Professor, 医学部, 講師
1986 – 1987: Kyushu University, Faculty of Medicine, Assistant, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Circulatory organs internal medicine / Circulatory organs internal medicine
Except Principal Investigator
Circulatory organs internal medicine / Circulatory organs internal medicine
Keywords
Principal Investigator
ラット / 循環調節 / 交感神経活動 / 家兎 / 遺伝子治療 / 細胞移植 / 一酸化窒素 / Insulin / Vasodilation / Hypertension … More / 高血圧 / 心筋虚血 / 心筋梗塞 / 神経反射 / 心レセプタ- / ホワイトノイズ法 / フ-リエ変換 / 周波数解析 / 心不全 / レニン-アンジオテンシン系 / 中枢神経系 / 移植後冠動脈硬化 / 心臓移植 / TNF-α / リモデリング / 血管新生 / 再生医学 / 遺伝子発現 / がん / 高脂血症 / アンジオテニシンII / サイトカイン / 血管内皮 / 腎不全 / Asymmetric Dimethylarginine / ADMA / syndromex / インシュリン / 脳室内投与 / Syndromex / 脳 / 交感神経 / 血圧変動 / テレメトリー / 中枢 / NO / L-NMMA / nitricoxide / hypertension / brain / sympathetic nervous system / blood pressure variability, / 遺伝子導入 / 肺高血圧症 / モノクロタリン / プロスタグランジン合成酵素 / シクロオキシゲナーゼ合成酵素 / 肺高血圧 / レトロウイルス / STAT3 / レトロウイルスベクター / pulmonary hypertension / prostacyclin / gene therapy / stem cel / cell transplantation / macrophages / 心房性利尿ホルモン / 腎交感神経 / 大動脈減圧神経 / 動脈圧受容体 / 大動脈径 / 迷走神経 / 腎機能 / atrial natriuretic peptide / renal sympathetic nerve / aortic depressor nerve / aortic diameter / aortic baroreceptors / vagus / rabbits … More
Except Principal Investigator
心不全 / 血管内皮 / 血管新生 / 内皮前駆細胞 / 血管形成 / substance P / serotonin / 動脈硬化 / 高血圧 / GABA / muscimol / sympathetic nerve activity / MCP-1 / SOCS / STAT3 / 内非依存性血管拡張 / 前椀血流量 / アセチルコリン / Lーarginine / No / L-アルジニン / サブスタンス-P / nitnic oxide / L-arginine / スライス標本 / NMMA / ヘモグロビン / メチレンブルー / nitric oxide / 内皮由来血管弛緩物質 / ブタ / 冠動脈 / L-NAME / L-NMMA / 心筋細胞 / 細胞増殖因子 / レトロウイルス / 細胞タカルシウム濃度 / FGF受容体 / 心臓発生 / 心機能 / 虚血骨格筋 / 骨髄細胞 / 内皮細胞 / CD34陽性細胞 / 自己移植 / 虚血性心疾患 / 血管再生 / 慢性閉塞性動脈硬化症 / 血管内皮細胞 / 側副血管 / 骨格筋栄養血流量 / handgrip運動 / カプトリル / couonay spasm / endo the lium / EDRF / coronary spasm / endothelium / substaucep / 冠攣縮 / 内皮細胞依存性血管弛緩因子 / セロトニン / サブスタンスP / 冠動脈攣縮 / 心筋虚血 / Ca^<2+>ーカイネティックス / Ca^<2+>チャネル / 血管内皮細胞依存性弛緩 / coronary artery spasm / endothelium-derived relaxing factor / dysfunction / 境界型高血圧ラット / 食塩負荷 / 振盪ストレス刺激 / 交感神経活動 / 食塩 / 境界型高血圧 / ストレス / ムシモ-ル / ビククリン / 脳室内投与 / borderline hypertensive rat / NaCl / shaker stress / 血圧変動 / 炎症 / 線維化 / ケモカイン / アンジオテンシンII / 拡張障害 / リモデリング / 接着因子 / アンジオテニシンII / 拡張能障害 / blood pressure variability / myocardial fibrosis / hypertension / hypertrophy / macrophages / 生活習慣病 / 心リモデリング / 心筋線維化 / OLETFラット / 7ND遺伝子 / 左室拡張不全 / 心・血管リモデリング / 炎症細胞浸潤 / 酸化ストレス / TGF-β / Heart Failure / Cardiac Remodeling / Cardiac Fibrosis / OLETF Rat / Gene of 7ND / マクロファージ / インターロイキン6 / サイトカイン / JAK / STAT / SOCS3 / 酸化LDL / マクロファージ泡沫化 / atherosclerosis / macrophage / Interleukin-6 / 心肺圧受容体 / 高食塩食摂取 / 高血圧自然発生ラット / 心房性ナトリウム利尿ペブチド / 心房筋伸展 / Cardiopulmonary baroreflex / High salt intake / Spontaneously hypertensive rat / Atrial natriuretic peptide / 心房性Na利尿ペプチド / 圧受容器反射 / 腎交感神経 / 大動脈減圧神経 / 前腕血流量 / 心房性ナトリウム利尿ペプチド(ANP) / 反射性交感神経活動調節 / 動脈圧受容器 / 大動脈径 / 側枢室内投与 / ANP / baroreceptors / aortic depressor nerve / forearm blood flow Less
  • Research Projects

    (24 results)
  • Research Products

    (50 results)
  • Co-Researchers

    (38 People)
  •  Mechanism of Endothelial Dysfunction in Chronic Kidney DiseasePrincipal Investigator

    • Principal Investigator
      IMAIZUMI Tsutomu
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kurume University
  •  Analysis of the role of signaling suppressor SOCS3 in the development of atherosclerosis

    • Principal Investigator
      YASUKAWA Hideo
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kurume University
  •  骨髄単核細胞移植療法による虚血肢の遺伝子発現変化の網羅的解析と遺伝子治療への応用Principal Investigator

    • Principal Investigator
      今泉 勉
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kurume University
  •  EFFECTS OF EXAGGERATED BLOOD PRESSURE VARIABILITY ON CARDIAC REMODELING AND PERIVASCULAR INFLAMMATION

    • Principal Investigator
      KAI Hisashi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      KURUME UNIVERSITY
  •  A possible treatment strategy for cardiovascular remodeling by metabolic syndrome-The gene therapy for use of MCP-1 7ND mutated gene-

    • Principal Investigator
      KUWAHARA Fumitaka
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      KURUME UNIVERSITY
  •  NEW TREATMENT FOR PULMONAY HYPERTENSIONPrincipal Investigator

    • Principal Investigator
      IMAIZUMI Tsutomu
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      KURUME UNIVERSITY
  •  コロニー刺激因子を用いた新しい虚血部血管新生療法の開発-内皮前駆細胞動員療法-

    • Principal Investigator
      室原 豊明
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kurume University
  •  移植後冠動脈硬化に対する抗炎症性サイトカイン療法の試みPrincipal Investigator

    • Principal Investigator
      今泉 勉
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kurume University
  •  自己骨髄単核細胞移植による心筋梗塞後血管新生療法の実験的試み

    • Principal Investigator
      MUROHARA Toyoaki
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kurume University
  •  Role of brain nitric oxide in the development of experimental hypertension.Principal Investigator

    • Principal Investigator
      IMAIZUMI Tsutomu
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kurume University School of Medicine
  •  心不全における内皮依存性血管拡張能異常に関する研究

    • Principal Investigator
      竹下 彰
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  心臓発生過程および成熟心臓機能における線維芽細胞成長因子の役割の解明

    • Principal Investigator
      上野 光
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kyushu University
  •  Effects of Insulin on sympethetic tonePrincipal Investigator

    • Principal Investigator
      IMAIZUMI Tsutomu
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      KURUME UNIVERSITY
      Kyushu University
  •  心不全における内皮依存性血勘拡張能異常に関する研究

    • Principal Investigator
      竹下 彰
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  孤束核ニューロンのシナプス伝達における酸化窒素の役割に関する研究:特に逆行性精報伝達物質としての可能性について

    • Principal Investigator
      竹下 彰
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  心不全における内皮依存性血管拡張能異常に関する研究

    • Principal Investigator
      竹下 彰
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  心不全における交感神経緊張にアンジオテンシンが如何に関与するかについての研究Principal Investigator

    • Principal Investigator
      今泉 勉
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kyushu University
  •  Role of central GABA system in hypertension induced by high salt and stress.

    • Principal Investigator
      TAKESHITA Akira
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      KYUSHU UNIVERSITY
  •  Cellular and Molecular Mechanism Coronary Spasm

    • Principal Investigator
      KOYANAGI Samon, 丸岡 雄二
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      KYUSHU UNIVERSITY
  •  心筋虚血時の反射性循環調節異常に関する検討Principal Investigator

    • Principal Investigator
      今泉 勉
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kyushu University
  •  心不全における運動時の骨格筋栄養血流量調節に関する研究

    • Principal Investigator
      竹下 彰
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Kyushu University
  •  The role of atrial natriuretic peptide in control of circulation and body fluid in heart failure

    • Principal Investigator
      TAKESHITA Akira
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kyushu University
  •  Effects of atrial natriuretic peptide on renal nerve activityPrincipal Investigator

    • Principal Investigator
      TSUTOMU IMAIZUMI
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kyushu University
  •  Factors contributing to increases in circulating hypertensive peptides in genetic hypertension

    • Principal Investigator
      TAKESHITA Akira
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kyushu University

All 2012 2011 2010 2009 2004 2003 Other

All Journal Article Presentation

  • [Journal Article] Cardiac-Specific Deletion of SOCS-3 Prevents Development of Left Ventricular Remodeling After Acute Myocardial Infarction.2012

    • Author(s)
      Oba T, Imaizumi T(他14人16番目)
    • Journal Title

      J Am Coll Cardiol

      Volume: 59 Pages: 838-852

    • DOI

      10.1016/j.jacc.2011.10.887

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390249, KAKENHI-PROJECT-23659104, KAKENHI-PROJECT-23792094
  • [Journal Article] Inhibition of eNOS phosphorylation mediates endothelial dysfunction in renal failure: new effect of asymmetric dimethylarginine.2012

    • Author(s)
      Kajimoto H, Kai H, Imaizumi T(他6人9番目)
    • Journal Title

      Kidney Int

      Volume: 81 Pages: 762-768

    • DOI

      10.1038/ki.2011.476

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390249, KAKENHI-PROJECT-22590565, KAKENHI-PROJECT-22590903, KAKENHI-PROJECT-22791042, KAKENHI-PROJECT-23591210, KAKENHI-PROJECT-24390334, KAKENHI-PROJECT-24659640
  • [Journal Article] Low DBP may not be an independent risk for cardiovascular death in revascularized coronary artery disease patients2011

    • Author(s)
      Kai H, Imaizumi T(他5人7番目)
    • Journal Title

      J Hypertens

      Volume: 29 Pages: 1889-1896

    • DOI

      10.1097/hjh.0b013e32834a5a67

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390249
  • [Journal Article] Longest survivor of pulmonary atresia with ventricular septal defect-well-developed major aortopulmonary collateral arteries demonstrated by multidetector computed tomography2011

    • Author(s)
      Fukui D, Kai H, Imaizumi T(他9人12番目)
    • Journal Title

      Circulation

      Volume: 124 Pages: 2155-2157

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390249
  • [Journal Article] Augmented neovascularization with magnetized endothelial progenitor cells in rats with hind-limb ischemia2011

    • Author(s)
      Koiwaya H, Imaizumi T(他7人9番目)
    • Journal Title

      J Mol Cell Cardiol

      Volume: 51 Pages: 33-40

    • DOI

      10.1016/j.yjmcc.2011.03.012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390249
  • [Journal Article] Enhanced cardiac inflammation and fibrosis in ovariectomized hypertensive rats : a possible mechanism of diastolic dysfunction in postmenopausal women2011

    • Author(s)
      Mori T, Kai H, Imaizumi T(他7人10番目)
    • Journal Title

      Hypertena Research

      Volume: 34 Pages: 496-502

    • DOI

      10.1038/hr.2010.261

    • NAID

      10031163207

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390249, KAKENHI-PROJECT-21590943, KAKENHI-PROJECT-22590565
  • [Journal Article] Serum level of pigment epithelium-derived factor is a marker of atherosclerosis in humans2011

    • Author(s)
      Tahara N, Imaizumi T(他8人10番目)
    • Journal Title

      Atherosclerosis

      Volume: 219 Pages: 311-315

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390249
  • [Journal Article] Plasma aldosterone levels and development of insulin resistance: prospective study in a general population.2011

    • Author(s)
      Kumagai E, Imaizumi T(他15人17番目)
    • Journal Title

      Hypertension.

      Volume: 58 Pages: 1043-1048

    • DOI

      10.1161/hypertensionaha.111.180521

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390249, KAKENHI-PROJECT-23790713, KAKENHI-PROJECT-23790714
  • [Journal Article] Administration of pigment epithelium-derived factor inhibits left ventricular remodeling and improves cardiac function in rats with acute myocardial infarction2011

    • Author(s)
      Ueda S-I, Imaizumi T(他3人5番目)
    • Journal Title

      Am J Pathol

      Volume: 178 Pages: 591-598

    • DOI

      10.1016/j.ajpath.2010.10.018

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390249
  • [Journal Article] Simvastatin prevents large blood pressure variability-induced aggravation of cardiac hypertrophy in hypertensive rats by inhibiting RhoA/Ras-ERK pathways2011

    • Author(s)
      Takayama N, Kai H, Imaizumi T(他7人10番目)
    • Journal Title

      Hypertension Research

      Volume: 34 Pages: 341-347

    • DOI

      10.1038/hr.2010.229

    • NAID

      10031163179

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390249, KAKENHI-PROJECT-21590943, KAKENHI-PROJECT-22590565, KAKENHI-PROJECT-22791042
  • [Journal Article] Target blood pressure for treatment of isolated systolic hypertension in the elderly : Valsartan in elderly isolated systolic hypertension study2010

    • Author(s)
      Ogihara T, Imaizumi T(他12人12番目)
    • Journal Title

      Hypertension

      Volume: 56 Pages: 196-202

    • DOI

      10.1161/hypertensionaha.109.146035

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390249
  • [Journal Article] Autologous transplantation of bone marrow mononuclear cells improved ischemic peripheral neuropathy in humans2010

    • Author(s)
      Arima K, Kai H, Imaizumi T(他8人11番目)
    • Journal Title

      J Am Coll Cardiol

      Volume: 56 Pages: 238-239

    • DOI

      10.1016/j.jacc.2010.02.050

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390249
  • [Journal Article] Mesenchymal stem cell-based prostacyclin synthase gene therapy for pulmonary hypertension rats2010

    • Author(s)
      Takemiya K, Kai H, Imaizumi T(他3人6番目)
    • Journal Title

      Basic Res Cardiol

      Volume: 105 Pages: 409-417

    • DOI

      10.1007/s00395-009-0065-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390249
  • [Journal Article] Exaggerated blood pressure variability superimposed on hypertension aggravates cardiac remodeling in rats via angiotensin II system-mediated chronic inflammation2009

    • Author(s)
      Kudo H, Kai H, Imaizumi T(他10人13番目)
    • Journal Title

      Hypertension

      Volume: 54 Pages: 832-838

    • DOI

      10.1161/hypertensionaha.109.135905

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390249
  • [Journal Article] 慢性腎不全患者の心血管病変進展における内因性NO合成阻害物質(ADMA)の役割2009

    • Author(s)
      梶本英美、甲斐久史、今泉勉
    • Journal Title

      腎臓

      Volume: 32 Pages: 103-107

    • Data Source
      KAKENHI-PROJECT-21390249
  • [Journal Article] Higher heart rate may predispose to obesity and diabetes mellitus : 20-year prospective study in a general population2009

    • Author(s)
      Shigetoh Y, Imaizumi T(他8人10番目)
    • Journal Title

      Am J Hypertens

      Volume: 22 Pages: 151-155

    • DOI

      10.1038/ajh.2008.331

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390249
  • [Journal Article] 慢性腎不全患者の心血管病変進展における内因性NO 合成阻害物質(ADMA)の役割2009

    • Author(s)
      梶本英美、甲斐久史、今泉勉
    • Journal Title

      腎臓 32

      Pages: 103-107

    • Data Source
      KAKENHI-PROJECT-21390249
  • [Journal Article] Angiogenesis and vasculogenesis are impaired in the precocious-aging klotho mouse.2004

    • Author(s)
      Shimada T, Takeshita Y, Murohara T, Sasaki K, Egami K, Shintani S, Katsuda Y, Ikeda H, Nabeshima Y, Imaizumi T
    • Journal Title

      Criculation 110

      Pages: 1148-1155

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370234
  • [Journal Article] Advanced glycation end products activate mesangial TGF-β-Smad signaling via angiotensin II-type I receptor interaction.2004

    • Author(s)
      Fukami K, Ueda S, Yamagishi S, Kato S, Inagaki Y, Takeuchi M, Motoyama Y, Bucala R, Iida S, Tamaki K, Imaizumi T, Cooper EM, Okuda S
    • Journal Title

      Kidny Int 66

      Pages: 2137-2147

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370234
  • [Journal Article] Repeated gene transfer of naked prostacyclin synthase plasmid into skeletal muscle attenuates monocrotaline -induced pulmonary hypertension and prolongs survival in rats.2004

    • Author(s)
      Tahara N, Kai H, Niiyama H, Mori T, Sugi Y, Takayama N, Yasukawa H, Numaguchi Y, Matsui H, Okumura K, Imaizumi T
    • Journal Title

      Human Gene Ther 15

      Pages: 1270-1278

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370234
  • [Journal Article] Pressure-independent effects of angiotensin II on hypertensive myocardial fibrosis.2004

    • Author(s)
      Tokuda K, Kai H, Kuwahara F, Yasukawa H, Tahara N, Kudo H, Takemiya K, Koga M, Yamamoto T, Imaizumi T.
    • Journal Title

      Hypertension 43(2 pt2)

      Pages: 499-503

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590781
  • [Journal Article] Repeated gene transfers of naked prostacyclin synthase plasmid into skeletal muscles attenuate monocrotaline-induced pulmonary hypertension and prolong survival in rats.2004

    • Author(s)
      Tahara N, Kai H, Niiyama H, Mori T, Sugi Y, Takayama N, Yasukawa H, Numaguchi Y, Matsui H, Okamura K, Imaizumi T.
    • Journal Title

      Human Gene Ther 15(12)

      Pages: 1270-1278

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590780
  • [Journal Article] Repeated gene transfers of naked prostacyclin synthase plasmid into skeletal muscles attenuate monocrotaline-induced pulmonary hypertension and prolong survival in rats.2004

    • Author(s)
      Tahara N, Imaizumi T(全11名11番目)
    • Journal Title

      Human Gene Ther 15(12)

      Pages: 1270-1278

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370234
  • [Journal Article] Hypertensive myocardial fibrosis and diastolic dysfunction-Another model of inflammation-2004

    • Author(s)
      Kuwahara F, Kai H, Tokuda K, Takeya M, Takeshita A, Egashira K, Imaizumi T.
    • Journal Title

      Hypertension 43(4)

      Pages: 739-745

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590780
  • [Journal Article] Angiogenesis and vasculogenesis are impaired in precocious aging klotho mouse2004

    • Author(s)
      Shimada T, Imaizumi T, et al. (全10名 10番目)
    • Journal Title

      Circulation 110(9)

      Pages: 1148-1155

    • Data Source
      KAKENHI-PROJECT-15659191
  • [Journal Article] Inhibition of platelet adherence to mononuclear cells by α-tocopherol. Role of P-selectin.2004

    • Author(s)
      Murohara T, Ikeda H, Otsuka Y, Aoki M, Haramaki N, Katoh A, Takajo Y, Imaizumi T
    • Journal Title

      Circulation 110

      Pages: 141-148

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370234
  • [Journal Article] Hypertensive myocardial fibrosis and diastolic dysfunction-Another model of inflammation-.2004

    • Author(s)
      Kuwahara F, Kai H, Tokuda K, Takeya M, Takeshita A, Egashira K, Imaizumi T.
    • Journal Title

      Hypertension 43(4)

      Pages: 739-745

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590781
  • [Journal Article] Roles of endogenous monocyte chemoattractant protein-1 in ischemia-induced neovascularization..2004

    • Author(s)
      Niiyama H, Kai H, Yamamoto T, Shimada T, Sasaki K, Murohara T, Egashira K, Imaizumi T.
    • Journal Title

      J Am Coll Cardiol 44(3)

      Pages: 661-666

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590780
  • [Journal Article] Roles of endogenous monocyate chemoattractant protein-1 in ischemia-induced neovascularization.2004

    • Author(s)
      Niiyama H, Kai H, Yamamoto T, Shimada T, Sasaki K, Murohara T, Egashira K, Imaizumi T
    • Journal Title

      J Am Coll Cardiol 44

      Pages: 661-666

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370234
  • [Journal Article] Roles of endogenous monocyte chemoattractant protein-1 in ischemia-induced neovascularization.2004

    • Author(s)
      Niiyama H, Imaizumi T (全8名8番目)
    • Journal Title

      J Am Coll Cardiol 44(3)

      Pages: 661-666

    • Data Source
      KAKENHI-PROJECT-15659191
  • [Journal Article] Pressure-independent effects of angiotensin II on hypertensive myocardial fibrosis.2004

    • Author(s)
      Tokuda K, Kai H, Kuwahara F, Yasukawa H, Tahara N, Kudo H, Takemiya K, Koga M, Yamamoto T, Imaizumi T.
    • Journal Title

      Hypertension 43(2 pt2)

      Pages: 499-503

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590780
  • [Journal Article] Role of host angiotensin II type 1 receptor in tumor angiogenesis and growth.2003

    • Author(s)
      Egami K, Murohara T, Ikeda H, Shimada T, Sasaki K, Sugaya T, Ishii M, Akagi T, Matsuishi T, Imaizumi T
    • Journal Title

      J Clin Invest 112

      Pages: 67-75

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370234
  • [Journal Article] Rescue of hypercholesterolemia-related impairment of angiogenesis by oral folate supplementation.2003

    • Author(s)
      Sasaki K, Duan J, Murohara T, Ikeda H, Shintani S, Shimada T, Akita T, Egami K, Imaizumi T
    • Journal Title

      J Am Coll Cardiol 42

      Pages: 364-372

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370234
  • [Journal Article] Rho-kinase inhibition reduces neointima formation after vascular injury by enhancing Bax expression and apoptosis2003

    • Author(s)
      Shibata R, Kai H, Seki Y, Kusaba K, Takemiya K, Koga M, Jalalidin A, Tokuda K, Tahara N, Niiyama H, Nagata T, Kuwahara F, Imaizumi T.
    • Journal Title

      J Cardiovasc Pharmacol 42(suppl)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590780
  • [Journal Article] Inhibition of STAT3 prevents neointime formation by inhibiting proliferation and promoting apoptosis of neointimal smooth muscle cells.2003

    • Author(s)
      Shibata R, Kai H, Seki Y, Kato S, Wada Y, Hanakawa Y, Hashimoto K, Yoshimura A, Imaizumi T.
    • Journal Title

      Human Gene Ther 14(7)

      Pages: 601-610

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590780
  • [Journal Article] Inhibition of STAT3 prevents neointima formation by inhibiting proliferation and promoting apoptosis of neointimal smooth muscle cells.2003

    • Author(s)
      Shibata R, Kai H, Seki Y, Kato S, Wada Y, Hanakawa Y, Hashimoto K, Yoshimura A, Imaizumi T
    • Journal Title

      Human Gene Therapy 14

      Pages: 601-610

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370234
  • [Journal Article] Sub-depressor dose of angiotensin type-1 receptor blocker inhibits TGF-β-mediated perivascular fibrosis in hypertensive rat hearts.2003

    • Author(s)
      Tokuda K, Kai H, Kuwahara F, Imaizumi T
    • Journal Title

      J Cardiovasc Pharmacol 42(suppl)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590780
  • [Journal Article] an IL-6 family cytokine, upregulates matrix metalloproteinase-9 through the MEK-ERK pathway in cultured smooth muscle cells.2003

    • Author(s)
      Nagata T, Kai H, Shibata R, Koga M, Yoshimura A, Imaizumi T, Oncostatin M
    • Journal Title

      Arterioscl Thromb Vasc Biol 23

      Pages: 588-593

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590780
  • [Journal Article] Cardiomyocyte-specific transgenic expression of lysyl oxidase-like protein-1 induces cardiac hypertrophy in mice

    • Author(s)
      Ohmura H, Imaizumi T(他8人10番目)
    • Journal Title

      Hypertens Res

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390249
  • [Presentation] Inhibition of CaMKII/ERK-mediated eNOS phosphorylation by asymmetric dimethylarginine is novel molecular mechanism of endothelial dysfunction in chronic kidney disease mice2012

    • Author(s)
      Kajimoto H, Kai H, Aoki H, Yasuoka S, Anegawa T, Imaizumi T
    • Organizer
      76th Annual Scientific Meeting of the Japanese Circulation Society
    • Place of Presentation
      Fukuoka, Japan
    • Data Source
      KAKENHI-PROJECT-21390249
  • [Presentation] Inhibition of CaMKII-and ERK-mediated eNOS phosphorylation impairs endothelial function in renal failure mice : New effect of asymmetric dimethylarginine2011

    • Author(s)
      Kajimoto H, Kai H, Aoki H, Yasuoka S, Anegawa T, Imaizumi T
    • Organizer
      American Heart Association's Scientific Sessions
    • Place of Presentation
      Orlando
    • Data Source
      KAKENHI-PROJECT-21390249
  • [Presentation] Increased circulating asymmetric dimethylarginine in chronic kidney disease mice induces endothelial dysfunction by inhibiting Ca/Calmodulin-dependent protein kinase II-eNOS signaling2010

    • Author(s)
      Kajimoto H, Kai H, Aoki H, Yasuoka S, Anegawa T, Imaizumi T
    • Organizer
      American Heart Association's Scientific Sessions
    • Place of Presentation
      Chicago, USA
    • Data Source
      KAKENHI-PROJECT-21390249
  • [Presentation] Asymmetric dimethylarginine impairs endothelial function in CKD mice2010

    • Author(s)
      Kajimoto H, Kai H, Yasuoka S, Imaizumi T
    • Organizer
      ISN-Nexus Symposium 2010
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-21390249
  • [Presentation] Smad-Msx2 pathway plays an initial role in vascular calcification in CKD mice2010

    • Author(s)
      Kajimoto H, Kai H, Yasuoka S, Anegawa T, Imaizumi T
    • Organizer
      74th Annual Scientific Meeting of the Japanese Circulation Society
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-21390249
  • [Presentation] Asymmetric dimethylarginine triggers vascular dysfunction in CKD mice2010

    • Author(s)
      Kajimoto H, Kai H, Yasuoka S, Imaizumi T
    • Organizer
      Xth World Congress of the International Society for Heart Research 2010 Kyoto
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-21390249
  • [Presentation] 血清Asymmetric Dimethylarginineの増加が腎機能低下における血管内皮障害を起こす2010

    • Author(s)
      Kajimoto H, Kai H, Yasuoka S, Imaizumi T
    • Organizer
      47th Annual Meeting of the Japanese Society of Pediatric Cardiology and Cardiac Surgery Chiba
    • Place of Presentation
      Japan
    • Data Source
      KAKENHI-PROJECT-21390249
  • [Presentation] 腎不全マウスにおける血清Asymmetric Dimethylarginineの上昇が血管内皮に与える影響2009

    • Author(s)
      Kajimoto H, Kai H, Yasuoka S, Aoki H, Anegawa T, Imaizumi T
    • Organizer
      The 32^<nd> Annual Scientific Meeting of the Japanese Society of Hypertension
    • Place of Presentation
      Shiga, Japan
    • Data Source
      KAKENHI-PROJECT-21390249
  • [Presentation] Asymmetric dimethylarginine is a paracrine regulator of vascular function in CKD2009

    • Author(s)
      Kajimoto H, Kai H, Yasuoka S, Aoki H, Anegawa T, Imaizumi T
    • Organizer
      The 13th Annual Scientific Meeting of the Japanese Heart Failure Society
    • Place of Presentation
      Fukuoka, Japan
    • Data Source
      KAKENHI-PROJECT-21390249
  • [Presentation] Asymmetric dimethylarginine triggers vasculo-renal interaction in CKD mice2009

    • Author(s)
      Kajimoto H, Kai H, Yasuoka S, Anegawa T, Aoki H, Imaizumi T
    • Organizer
      American Heart Association's Scientific Sessions
    • Place of Presentation
      Orlando, USA
    • Data Source
      KAKENHI-PROJECT-21390249
  • [Presentation] 血清Asymmetric Dimethylarginineの増加が腎不全マウスにおける内皮機能障害を起こす2009

    • Author(s)
      Kajimoto H, Kai H, Yasuoka S, Aoki H, Anegawa T, Imaizumi T
    • Organizer
      The 57th Annual Scientific Session of the Japanese College of Cardiology
    • Place of Presentation
      Sapporo, Japan
    • Data Source
      KAKENHI-PROJECT-21390249
  • 1.  TAKESHITA Akira (30038814)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 0 results
  • 2.  KAI Hisashi (60281531)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 34 results
  • 3.  砂川 賢二 (50163043)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  下川 宏明 (00235681)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  MUROHARA Toyoaki (90299503)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 5 results
  • 6.  NIIYAMA Hiroshi (30309778)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 7.  KANAIDE Hideo (80038851)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  KOYANAGI Samon (90128017)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  KUWAHARA Fumitaka (90279167)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 10.  友池 仁暢 (90112333)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  池田 久雄 (50168134)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  KAJIMOTO Hidemi (50349700)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 15 results
  • 13.  SUEISHI Katsuo (70108710)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  KOBAYASHI Sei (80225515)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  MATSUOKA Hedehiro (80248393)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  IWAMI Gensho (90203405)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  TAHARA Nobuhiro (10320186)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 18.  NAGATA Tsuyoshi (70289429)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  YASUKAWA Hideo (60289361)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  丹羽 正美 (20136641)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  上野 光 (50260378)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  服巻 信也 (90248352)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  江口 裕之 (60279164)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  加藤 宏司 (70279165)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  新谷 理 (20309777)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  佐々木 健一郎 (70320190)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  安岡 逸 (10461435)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 14 results
  • 28.  丸岡 雄二 (10190563)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  稲生 哲治 (10159965)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  中村 元臣 (60037322)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  徳田 圭亮 (80320191)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  SUZUKI Satoshi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  ANAGAWA Takahiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 34.  OKUDA Seiya
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 35.  大場 豊治
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 36.  吉川 邦子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 37.  横井 加奈子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 38.  上田 誠二
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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