yoshizawa naoko 吉沢直子 (須賀田直子)

Connect your ORCID iD *help

… Alternative Names

吉沢直子ヨシザワナオコ(スガタナオコ)

須賀田直子

YOSHIZAWA Naoko 吉沢直子

SUGATA Naoko 須賀田直子

吉沢直子(須賀田直子) ヨシザワナオコ

須賀田直子

Less

Researcher Number	30344071
Other IDs
Affiliation (Current)	2025: 公益財団法人東京都医学総合研究所, ゲノム医学研究センター, 主席研究員
Affiliation (based on the past Project Information) *help	2021 – 2023: 公益財団法人東京都医学総合研究所, ゲノム医学研究センター, 主席研究員 2016 – 2017: 公益財団法人東京都医学総合研究所, ゲノム医科学研究分野, 主席研究員 2012 – 2015: 公益財団法人東京都医学総合研究所, ゲノム医科学研究分野, 主任研究員 2011: (財)東京都医学総合研究所, ゲノム医科学研究分野, 主任研究員 2010: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 主任研究員 … More 2008 – 2010: Tokyo Metropolitan Organization for Medical Research, 東京都臨床医学総合研究所, 主任研究員 2007 – 2008: Tokyo Metropolitan Organization for Medical Research, Tokyo Metropolitan Institute of Medical Science, Researcher 2007: 東京都臨床医学総合研究所, 主任研究員 2007: Tokyo Metropolitan Organization for Medical Research, 東京都精神医学総合研究所, 主任研究員 2006: (財)東京都医学研究機構, 東京都臨床医学総合研究所, 主任研究員 2004: Tokyo Metropolitan Institute of Medical Science, Genome Dynamics Project, Senior Researcher, 東京都臨床医学総合研究所, 主任研究員 2003 – 2004: 財団法人東京都医学研究機構, 主任研究員 2002 – 2004: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 主任研究員 Less
Review Section/Research Field	Principal Investigator Molecular biology / Genetics/Chromosome dynamics / Cell biology Except Principal Investigator Basic Section 43050:Genome biology-related / Functional biochemistry / Molecular biology / Functional biochemistry / General medical chemistry
Keywords	Principal Investigator AND-1 / 複製フォーク / Cdc7 / Rif1 / Tipin / 初期胚 / DNA損傷 / 相同組換え修復 / コヒーシン / 染色体接着 … More / ゲノム安定性 / Timeless / ゲノム不安定性 / DNA修復 / 複製ストレス / 複製チェックポイント / DNA複製 / ２細胞期初期胚 / トランスポゾン / ２細胞期 / 遺伝子クラスター / H3K27Ac / DNAメチル化 / ヒストン修飾 / Zscan4 / エンハンサー / 内在性レトロウィルス / 2細胞期 / DNA replication / chromosome cohesion / recombinational repair / DNA damage / fork protection complex / replication checkpoint / replication fork / フォーク保護因子 / Calspin / Tim / 組換え修復 / 複製保護因子 / 未分化 / 胎生幹細胞 / クロマチン免疫沈降 / ES細胞 / 多能性幹細胞 / 修復組換え / 姉妹染色体交換 … More Except Principal Investigator oriP / 複製起点 / preRC / Epstein Barr Virus / Cdc7キナーゼ / 複製タイミング / 細胞周期 / de novo gene / 偽遺伝子化 / 遺伝子レパートリー / シスエレメント / de novo 遺伝子 / 祖先配列 / エンハンサー / プロモーター / 超並列レポーターアッセイ / 偽遺伝子 / de novo遺伝子 / cell cycle / EBNA1 protein / ORC complex / MCM complex / in vitro DNA replication / in vitro DNA複製 / in viitro DNA複製 / Epstein Brrr Virus / EBNAタンパク質 / ORC複合体 / MCM複合体 / in vitro DNA 複製 / 構造解析 / 染色体ダイナミクス / リン酸化 / 染色体DNA複製 / 脳発生 / 細胞分裂 / 乗り越えDNA合成 / 減数分裂期組換え / チェックポイント / 染色体DNA複製開始 / MCMタンパク質 / チェックポイント制御 / DNAヘリカーゼ / DNA複製 / 遺伝子の情報発現と複製 / EBウィルス / MCM / 複製開始複合体 / ORC / 遺伝子治療 / エピゾームベクター Less

Elucidation of de novo gene birth and pseudogenization processes via reconstruction of ancestral transcriptional regulation
- Principal Investigator
  
  HARA Yuichiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43050:Genome biology-related
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Functional analysis of Rif1 in regulating muticopy gene cluster and super state of pluripotent stem cellsPrincipal Investigator
- Principal Investigator
  
  YOSHIZAWA Naoko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Genetics/Chromosome dynamics
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Studies on the functions and structures of Cdc7 kinase, essential for initiation of DNA replication
- Principal Investigator
  
  MASAI Hisao
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Molecular biology
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Mechanism of the replication stress response of variable replication fork complexesPrincipal Investigator
- Principal Investigator
  
  YOSHIZAWA=SUGATA Naoko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Mechanisms of genomic stability maintenance by replication scaffold protein, AND-1Principal Investigator
- Principal Investigator
  
  YOSHIZAWA Naoko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Elucidation of DNA replication program in mammalian cells
- Principal Investigator
  
  MASAI Hisao
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Roles of fork protection complex and cdc7 kinase in fork-stabilization and replication checkpointPrincipal Investigator
- Principal Investigator
  
  YOSHIZAWA Naoko
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
遺伝子治療のための染色体複製起点由来のエピゾームベクターの開発に関する研究
- Principal Investigator
  
  MASAI Hisao
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Enzymatic analyses of eukaryotic chromosomal DNA replication using the Epstein Barr Virus-derived oriP replicon
- Principal Investigator
  
  MASAI Hisao
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Metropolitan Organization for Medical Research

[Book] The Initiation of DNA Replication in Eukaryotes2016
- Author(s)
  Yoshizawa-Sugata, N., Yamazaki, S. and Masai, H.
- Total Pages
  15
- Publisher
  Springer International Publishing
- Data Source
  KAKENHI-PROJECT-15K07164
[Book] Methods in Molecular Biology2014
- Author(s)
  Yoshizawa-Sugata, N, and Masai.
- Publisher
  Cell cycle synchronization and flow cytometry analysis of mammalian cells
- Data Source
  KAKENHI-PROJECT-23570243
[Journal Article] Oligomer formation and G-quadruplex binding by purified murine Rif1 protein, a key organizer of higher-order chromatin architecture2018
- Author(s)
  Moriyama Kenji、Yoshizawa-Sugata Naoko、Masai Hisao
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 293 Issue: 10 Pages: 3607-3624
- DOI
  10.1074/jbc.ra117.000446
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K07164, KAKENHI-PROJECT-16K14675, KAKENHI-PROJECT-17H01418
[Journal Article] Telomere-binding factors in the regulation of DNA replication2017
- Author(s)
  Masai, H., Kanoh, Y., Moriyama, K., Yamazaki, S., Yoshizawa, N., and Matsumoto, S.
- Journal Title
  
  Genes Genet. Syst.
  
  Volume: 92 Issue: 3 Pages: 119-125
- DOI
  10.1266/ggs.17-00008
- NAID
  130006316033
- ISSN
  1341-7568, 1880-5779
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K14675, KAKENHI-PROJECT-15K07164, KAKENHI-PROJECT-17H01418
[Journal Article] Epigenetic Regulation of the Blimp-1 Gene (Prdm1) in B Cells Involves Bach2 and Histone Deacetylase 3*2016
- Author(s)
  Tanaka H
- Journal Title
  
  JBC
  
  Volume: 291 Issue: 12 Pages: 6316-6330
- DOI
  10.1074/jbc.m116.713842
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12203, KAKENHI-PLANNED-23116003, KAKENHI-PUBLICLY-26114723, KAKENHI-PROJECT-15H02506, KAKENHI-PROJECT-25460351, KAKENHI-PROJECT-25460352, KAKENHI-PROJECT-25650014, KAKENHI-PROJECT-26281020, KAKENHI-PROJECT-15K07164, KAKENHI-PROJECT-26251004, KAKENHI-PROJECT-16K14675
[Journal Article] Cell cycle synchronization and flow cytometry analysis of mammalian cells2014
- Author(s)
  Yoshizawa-Sugata, N. and Masai, H.
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570243
[Journal Article] Cell cycle synchronization and flow cytometry analysis of mammalian cell.2014
- Author(s)
  Yoshizawa-Sugata, N. and Masai, H.
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 1170 Pages: 279-293
- DOI
  10.1007/978-1-4939-0888-2_13
- ISBN
  9781493908875, 9781493908882
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-14F03511, KAKENHI-PROJECT-23247031, KAKENHI-PROJECT-23657081, KAKENHI-PUBLICLY-24114520, KAKENHI-PUBLICLY-25125724, KAKENHI-PROJECT-25650014, KAKENHI-PUBLICLY-26114723, KAKENHI-PROJECT-26251004
[Journal Article] Role of multifunctional transcription factor TFII-I and putative tumour suppressor DBC1 in cell cycle and DNA double strand damage repair2013
- Author(s)
  Tanikawa M, Wada Hiraike O, Yoshizawa Sugata N , Shirane A, Hirano M, Hiraike H, Miyamoto Y, Sone K, Ikeda Y, Kashiyama T, Oda K, Kawana K, Katakura Y, Yano T, Masai H, Roy AL, Osuga Y, Fujii T
- Journal Title
  
  Br. J. Cancer
  
  Volume: 109 Pages: 3042-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570243
[Journal Article] Epstein-Barr nuclear antigen 1 (EBNA1)-dependent recruitment of origin recognition complex(Orc) on oriP of Epstein-Barr virus with purified proteins:stimulation by Cdc6 through its direct interaction with EBNA1.2012
- Author(s)
  Moriyama K
- Journal Title
  
  The Journal of biological chemistry
  
  Volume: 287 Issue: 28 Pages: 23977-23994
- DOI
  10.1074/jbc.m112.368456
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20114006, KAKENHI-PROJECT-23247031, KAKENHI-PROJECT-23570243, KAKENHI-PROJECT-23657081, KAKENHI-PROJECT-24370071, KAKENHI-PUBLICLY-24114520
[Journal Article] EBNA1-dependent recruitment of Orc on OriP of Epstein-Barr virus with purified proteins : Stimulation by Cdc6 through Its direct interaction with EBNA12012
- Author(s)
  Moriyama K, Yoshizawa Sugata N, Obuse C, Tsurimoto T, and Masai H
- Journal Title
  
  Biological Chemistry
  
  Volume: 287 Pages: 23977-23994
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570243
[Journal Article] Eukaryotic DNA Replication : where, when and how?2010
- Author(s)
  Hisao Masai, Seiji Matsumoto, Zhiying You, Naoko Yoshizawa-Sugata, Masako Oda
- Journal Title
  
  Annual Review of Biochemistry 79
  
  Pages: 89-130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570173
[Journal Article] Eukaryotic chromosome DNA replication : where, when, and how?2010
- Author(s)
  Masai H, Matsumoto S, You Z, Yoshizawa-Sugata N, Oda M
- Journal Title
  
  Annu.Rev.Biochem.
  
  Volume: 79 Pages: 89-130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570173
[Journal Article] Eukaryotic DNA Replication : where, when and how?2010
- Author(s)
  Masai, H., Matsumoto, S., You, Z., Yoshizawa-Sugata, N., Oda, M.
- Journal Title
  
  Ann.Rev.Biochem. (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570173
[Journal Article] Roles of human AND-1 in chromosome transactions in S phase.2009
- Author(s)
  Naoko Yoshizawa-Sugata, Hisao Masai
- Journal Title
  
  J. Biol. Chem. 284(31)
  
  Pages: 20718-20728
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570173
[Journal Article] Roles of human AND-1 in chromosome transactions in S phase.2009
- Author(s)
  Yoshizawa-Sugata, N., and Masai, H.
- Journal Title
  
  J. Biol. Chem. [Epub ahead of print]
  
  Pages: 0-0
- Data Source
  KAKENHI-PROJECT-18207009
[Journal Article] Roles of human AND-1 in chromosome transactions in S phase2009
- Author(s)
  Yoshizawa-Sugata N., Masai H.
- Journal Title
  
  J.Biol.Chem. Vol.284
  
  Pages: 20718-20728
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570173
[Journal Article] Human Tim/timeless-interacting Protein, Tipin, Is Required for Efficient Progression of S Phase and DNA Replication Checkpoint2007
- Author(s)
  N.Yoshizawa-Sugata & H.Masai
- Journal Title
  
  J. Biol. Chem 282(4)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18570169
[Journal Article] Human Tim/Timeless-interacting protein,Tipin,is required for efficient progression of S phase and DNA replication checkpoint.2007
- Author(s)
  Yoshizawa-Sugata, N.
- Journal Title
  
  J.Biol.Chem. 282
  
  Pages: 2729-2740
- Data Source
  KAKENHI-PROJECT-18207009
[Journal Article] (2007) Human Tim/Timeless interiacting protein, Tipin, is required for efficient progression of S phase and DNA replication checkpoint.2007
- Author(s)
  N Yoshizawa Sugata, and H Masai
- Journal Title
  
  J. Biol. Chem. 282, (4)
  
  Pages: 2729-2740
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570169
[Journal Article] "Human Tim/Timeless-interacting protein,Tipin,is required for effcient progression of S phase and DNA replication checkpoint."2007
- Author(s)
  Yoshizawa-Sugata, N., Masai, H.
- Journal Title
  
  J.Biol.Chem. 282
  
  Pages: 2729-2740
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18207009
[Journal Article] Human Tim/Timeless-interacting protein, Tipin, is required for efficient progression of S phase and DNA replication checkpoint.2007
- Author(s)
  Yoshizawa-Sugata, N. and Masai, H.
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 2729-2740
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18207009
[Journal Article] Human Tim/Timeless-interacting Protein, Tipin, IsRequired for Efficient Progression of S Phase and DNA Replication Checkpoint2007
- Author(s)
  N.Yoshizawa, H.Masai
- Journal Title
  
  J. Biol. Chem 282(4)
  
  Pages: 2729-2740
- Data Source
  KAKENHI-PROJECT-18570169
[Journal Article] A second human Dbf4/ASK-related protein, Drf1/ASKL1 is required for efficient completion of S and M phases.2005
- Author(s)
  Yoshizawa, N., Ishii, A., Taniyama, C., Matsui, E., Arai, K., Masai, H.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 11362-113070
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14208079
[Journal Article] A second human Dbf4/ASK-related protein, Drf1/ASKL1 is required for efficient completion of S and M phases.2005
- Author(s)
  Yoshizawa, N., Ishii, A., Taniyama, C., Matsui, E., Arai, K., Masai,H.
- Journal Title
  
  J. Biol. Chem. 280
  
  Pages: 13062-13070
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14208079
[Journal Article] A second human Dbf4/ASK-related protein, Crf1/ASKL1 is required for efficient completion of S and M phases.2005
- Author(s)
  Yoshizawa, N., Ishii, A., Taniyama, C., Matsui, E., Arai, K., Masai, H.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 13062-13070
- Data Source
  KAKENHI-PROJECT-14208079
[Journal Article] A second human Dbf4/ASK-related protein, Drf1/ASKL1 is required for efficient completion of S and M phases.2005
- Author(s)
  Yoshizawa, N., Ishii, A., Taniyama, C., Matsui, E., Arai, K., Masai, H.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 13062-13070
- Data Source
  KAKENHI-PROJECT-15659072
[Presentation] 祖先転写制御の実験的復元から遺伝子が生まれる・消える過程を探る2023
- Author(s)
  原雄一郎、吉沢直子、豊田敦、川路英哉
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K06132
[Presentation] マウスES細胞におけるZscan4の発現脱抑制とRif1依存的なクロマチン構造変化の解析2017
- Author(s)
  吉沢直子、正井久雄
- Organizer
  生命科学系学会合同年次大会（第40回日本分子生物学会）
- Data Source
  KAKENHI-PROJECT-15K07164
[Presentation] Rif1 regulates expression of cluster genes in mouse ES cells and reprogramming2016
- Author(s)
  Yoshizawa-Sugata N, Ono T, Yamazaki S, Shindo M, Nishito Y, Masai H
- Organizer
  International Symposium on Epigenome Dynamics and Regulation in Germ Cells
- Place of Presentation
  京都大学百周年時計台記念館国際交流ホール（京都府京都市）
- Year and Date
  2016-02-17
- Data Source
  KAKENHI-PROJECT-15K07164
[Presentation] Early zygotic gene expression and organized differentiation are regulated by a conserved chromatin binding protein Rif1 in mouse ES cells.2016
- Author(s)
  Naoko Yoshizawa-Sugata and Hisao Masai
- Organizer
  3R Symposium
- Place of Presentation
  ホテル一畑（島根県松江市）
- Year and Date
  2016-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07164
[Presentation] Rif1によるES細胞の遺伝子クラスターの発現及びリプログラミングの制御2015
- Author(s)
  吉沢直子、小野富男、山崎聡、進藤真由美、西藤泰昌、正井久雄
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-15K07164
[Presentation] Rif1のES 細胞での未分化能維持、および体細胞のリプログラミングにおける機能解析:クロマチン構造制御因子としての可能性2013
- Author(s)
  吉沢直子,正井久雄
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23570243
[Presentation] Rif1のES細胞での未分化能維持、および体細胞のリプログラミングにおける機能解析、クロマチン構造制御因子としての可能性2013
- Author(s)
  吉沢直子, 正井久雄
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸(ポスター発表)
- Data Source
  KAKENHI-PROJECT-23570243
[Presentation] The maintenance of undifferentiated state in mouse embryonic stem cells by Rap1 interacting factor-1 (Rif1), a potential regulator of chromatin architecture in nuclei2012
- Author(s)
  Yoshizawa Sugata N、Kakusho N, Yamazaki S, Fukatsu R, and Masai H
- Organizer
  分子生物学会年会
- Place of Presentation
  横浜(口頭発表およびポスター)
- Data Source
  KAKENHI-PROJECT-23570243
[Presentation] Cell cycle regulation of mouse embryonic stem cells: E2F- and Emi1-mediated positive feedback regulation2012
- Author(s)
  Hisao Masai, Hiroko Fujii, Naoko Kakusho, Sayuri Ito, Satoshi Yamazaki, and Naoko Yoshizawa
- Organizer
  4th Southeast Stem Cell Consortium Workshop at Florida State University
- Place of Presentation
  アメリが合衆国、フロリダ州
- Data Source
  KAKENHI-PROJECT-23570243
[Presentation] Regulation of replication program in fission yeast and human cells2012
- Author(s)
  Hisao Masai, Satoshi Yamazaki, Yutaka Kanoh, Motoshi Hayano, Seiji Matsumoto, Naoko Yoshizawa, Rino Fukatsu, Naoko Kakusho, and Michie Shimmoto
- Organizer
  8th 3R meeting
- Place of Presentation
  兵庫県淡路島
- Data Source
  KAKENHI-PROJECT-23570243
[Presentation] The maintenance of undifferentiated state in mouse embryonic stem cells by Rap1 interacting factor-1 (Rif1), a potential regulator of chromatin architecture in nuclei2012
- Author(s)
  Yoshizawa, N., Kakusho, N., Yamazaki, S., Fukatsu, R. and Masai, H.
- Organizer
  日本分子生物学会
- Place of Presentation
  神奈川県横浜市
- Data Source
  KAKENHI-PROJECT-23570243
[Presentation] Rif1はクロマチン高次構築を制御してES細胞特異的な核内構造を形成する2012
- Author(s)
  吉沢直子, 覚正直子, 山崎聡, 深津理乃, 正井久雄
- Organizer
  第35回日本分子生物学会年会ワークショップ
- Place of Presentation
  福岡(口頭発表およびポスター発表)
- Data Source
  KAKENHI-PROJECT-23570243
[Presentation] The maintenance of pluripotency in mouse embryonic stem cells by Rif1, a potential regulator of replication domains2011
- Author(s)
  Yoshizawa,N., Kakusho, N., Yamazaki, S., Fukatsu, R. and Masai, H.
- Organizer
  Joint CSH-Asia / ISSCR Conference on Cellular Programs & Reprogramming
- Place of Presentation
  中国・蘇州
- Data Source
  KAKENHI-PROJECT-23570243
[Presentation] The maintenance of pluripotency in mouse embryonic stem cells by Rif1, a potential regulator of replication domains2011
- Author(s)
  Yoshizawa Sugata N、Kakusho N, Yamazaki S, Fukatsu R, and Masai H
- Organizer
  Joint CSH-Asia / ISSCR Conference on Cellular Programs & Reprogramming
- Place of Presentation
  中国,蘇州(ポスター発表)
- Data Source
  KAKENHI-PROJECT-23570243
[Presentation] The maintenance of undifferentiated state in mouse embryonic stem cells by Rap1 interacting factor-1 (Rif1), a potential regulator of chromatin architecture in nuclei2011
- Author(s)
  Yoshizawa,N., Kakusho, N., Yamazaki, S., Fukatsu, R. and Masai, H.
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23570243
[Presentation] Regulation of replication program and maintenance of genetic integrity2010
- Author(s)
  Hisao Masai, Satoshi Yamazaki, Motoshi Hayano, Yutaka Kanoh, Seiji Matsumoto, Naoko Kakusho, Ai, Ishii, Michie Shimmoto, Masako Oda, Naoko Yoshizawa, Sayuri Itoh, Satomi Kudo
- Organizer
  第33回日本分子生物学会(BMB2010)
- Place of Presentation
  神戸ポートアイランド(口頭発表)
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-20570173
[Presentation] Regulation of origin firing program and checkpoint by Cdc7, Mrc1 and Rif12010
- Author(s)
  Hisao Masai, Seiji Matsumoto, Motoshi Hayano, Yutaka Kanoh, Satoshi Yamazaki, Satomi Kudo, Naoko Kakusho, Rino Fukatsu, Naoko Yoshizawa, Ai, Ishii
- Organizer
  7th 3R(Replication, Recombination & Repair)meeting 2010
- Place of Presentation
  Toyama conference center(Toyama)
- Year and Date
  2010-10-29
- Data Source
  KAKENHI-PROJECT-20570173
[Presentation] Roles of human replisome component AND-1 and Tim in S phase chro-mosome transaction2010
- Author(s)
  Naoko Yoshizawa, Hisao Masai
- Organizer
  7th 3R(Replication, Recombination & Repair)meeting 2010
- Place of Presentation
  Toyama conference center(Toyama)
- Year and Date
  2010-10-28
- Data Source
  KAKENHI-PROJECT-20570173
[Presentation] Regulation of origin firing program and checkpoint by Cdc7, Mrc1 and Rif12010
- Author(s)
  Hisao Masai, Seiji Matsumoto, Motoshi Hayano, Yutaka Kanoh, Satoshi Yamazaki, Satomi Kudo, Naoko Kakusho, Rino Fukatsu, Naoko Yoshizawa, Ai, Ishii
- Organizer
  7th 3R Symposium
- Place of Presentation
  Toyama conference center, Toyama(口頭発表)
- Year and Date
  2010-10-29
- Data Source
  KAKENHI-PROJECT-20570173
[Presentation] Roles of human replisome component AND-1 and Tim in S phase chromosome transaction2010
- Author(s)
  Naoko Yoshizawa-Sugata, Hisao Masai
- Organizer
  7th 3R Symposium (ポスター発表)
- Place of Presentation
  Toyama conference center, Toyama
- Year and Date
  2010-10-28
- Data Source
  KAKENHI-PROJECT-20570173
[Presentation] Regulation of replication program and maintenance of genetic integrity2010
- Author(s)
  Hisao Masai, Satoshi Yamazaki, Motoshi Hayano, Yutaka Kanoh, Seiji Matsumoto, Naoko Kakusho, Ai, Ishii, Michie Shimmoto, Masako Oda, Naoko Yoshizawa, Sayuri Itoh, Satomi Kudo
- Organizer
  第33回日本分子生物学会(BMB2010)
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-20570173
[Presentation] Human AND-1 is required for efficient DNA replication, checkpoint activation and homologous recombinational repair2009
- Author(s)
  Yoshizawa-Sugata N., Masai H.
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜パシフィコ(神奈川県)(英語での口頭発表)
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-20570173
[Presentation] Human AND-1 is required for efficient DNA replication, checkpoint activation and homologous recombinational repair2009
- Author(s)
  Naoko Yoshizawa, Hisao Masai
- Organizer
  第32回日本分子生物学会年会(口頭・ポスター発表)
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-20570173
[Presentation] Human AND-1 is required for efficient DNA replication, checkpoint activation and homologous recombinational repair2008
- Author(s)
  Naoko Yoshizawa-Sugata, Hisao Masai
- Organizer
  6th 3R Symposium (ポスター発表)
- Place of Presentation
  Tsumagoi, Shizuoka
- Data Source
  KAKENHI-PROJECT-20570173
[Presentation] The mechanism of Human AND-1 protein in regulating chromosome dynamics.2008
- Author(s)
  Naoko Yoshizawa and Hisao Masai
- Organizer
  1st public opening meeting of specific ares research 'Chromosme cycle'
- Place of Presentation
  Tokyo university
- Year and Date
  2008-01-07
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570169
[Presentation] Regulation of replication fork integrity during S phase2008
- Author(s)
  Hisao Masai, Motoshi Hayano, Seiji Matsumoto, Yutaka Kanoh, Mika Yokoyama, Michiyo Shimmoto, Naoko Kakusho, Naoko Yoshizawa, Taku Tanaka
- Organizer
  第31回日本分子生物学会(BMB2008)(シンポジウム口頭発表)
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-20570173
[Presentation] Human AND-1 is required for efficient DNA replication, checkpoint activation and homologous recombination repair2008
- Author(s)
  Naoko Yoshizawa-Sugata, Hisao Masai
- Organizer
  EMBO Conference on "Replication and Segregation of Chromosomes"
- Place of Presentation
  Geilo, Norway
- Data Source
  KAKENHI-PROJECT-20570173
[Presentation] Human AND-1 is required for efficient DNA replication, checkpoint activation and homologous recombinational repair2008
- Author(s)
  Naoko Yoshizawa-Sugata, Hisao Masai
- Organizer
  6th 3R (Replication, Repair, Recombination) Symposium
- Place of Presentation
  Tsumagoi, Shizuoka
- Data Source
  KAKENHI-PROJECT-20570173
[Presentation] Regulation of replication fork in maintenance of genomic integrity2008
- Author(s)
  Hisao Masai, Motoshi Hayano, Seiji Matsumoto, Yutaka Kanoh, Michie Shimmoto, Mika Yokoyama, Taku Tanaka, Naoko Kakusho, Noako Yoshizawa, You Zhiying, Sayuri Ito, Chika Taniyama, Ai Ishii
- Organizer
  6th 3R (Replication, Repair, Recombination) Symposium
- Place of Presentation
  Tsumagoi, Shizuoka
- Data Source
  KAKENHI-PROJECT-20570173
[Presentation] Human AND-1 is required for efficient DNA replication, checkpoint activation and homologous recombination repair2008
- Author(s)
  Naoko Yoshizawa-Sugata, Hisao Masai
- Organizer
  EMBO Conference on Replication and Segregation of Chromosomes (ポスター発表)
- Place of Presentation
  Geilo, Norway
- Data Source
  KAKENHI-PROJECT-20570173
[Presentation] Regulation of replication fork integrity during S phase2008
- Author(s)
  Hisao Masai, Motoshi Hayano, Seiji Matsumoto, Yutaka Kanoh, Mika Yokoyama, Michiyo Shimmoto, Naoko Kakusho, Naoko Yoshizawa, Taku Tanaka
- Organizer
  BMB (Biochemistry and Molecular Biology) 2008
- Place of Presentation
  神戸ポートアイランド(シンポジウム)
- Data Source
  KAKENHI-PROJECT-18207009
[Presentation] ヒトAND-1タンパク質による染色体動態制御機構の解析2008
- Author(s)
  吉沢直子, 正井久雄
- Organizer
  文部科学省特定領域研究「染色体サイクルの制御ネットワーク」第一回公開領域会議
- Place of Presentation
  東京大学弥生講堂
- Year and Date
  2008-01-07
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570169
[Presentation] Regulation of replication fork in maintenance of genomic integrity2008
- Author(s)
  Hisao Masai, Motoshi Hayano, Seiji Matsumoto, Yutaka Kanoh, Michie Shimmoto, Mika Yokoyama, Taku Tanaka, Naoko Kakusho, Naoko Yoshizawa, You Zhiying, Sayuri Ito, Chika Taniyama, Ai Ishii
- Organizer
  6th 3R Symposium
- Place of Presentation
  Tsumagoi, Shizuoka(招待講演)
- Data Source
  KAKENHI-PROJECT-20570173
[Presentation] Regulation of replication fork in maintenance of genomic integrity2008
- Author(s)
  Hisao Masai, Motoshi Hayano, Seiji Matsumoto, Yutaka Kanoh, Michie Shimmoto, Mika Yokoyama, Taku Tanaka, Naoko Kakusho, Naoko Yoshizawa-Sugata, You Zhiying, Sayuri Ito, Chika Taniyama, Ai Ishii
- Organizer
  6th 3R Symposium
- Place of Presentation
  Tsumagoi, Shizuoka
- Data Source
  KAKENHI-PROJECT-18207009
[Presentation] Regula tion of replication fork integrity during S phase.2008
- Author(s)
  Hisao Masai, Motoshi Hayano, Seiji Matsumoto, Yutaka Kanoh, Mika Yokoyama, Michie Shinmoto, Naoko Kakusho, Naoko Yoshizawa and Taku Tanaka
- Organizer
  BMB2008
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-18207009
[Presentation] Roles of human AND-1 protein in maintenance of replication fork integrity and sister chromatid cohesion.2007
- Author(s)
  Naoko Yoshizawa and Hisao Masai
- Organizer
  BMB 2007
- Place of Presentation
  Yokohama Paciffico
- Year and Date
  2007-12-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570169
[Presentation] ヒトAND-1タンパク質による染色体動態制御機構の解析(一般口頭発表)2007
- Author(s)
  吉沢直子
- Organizer
  BMB2007(第30回日本分子生物学会年会・第80回日本生化学会大会合同大会)
- Place of Presentation
  横浜パシフィコ
- Year and Date
  2007-12-19
- Data Source
  KAKENHI-PROJECT-18570169
[Presentation] ヒトAND-1タンパク質による染色体動態制御機構の解析2007
- Author(s)
  吉沢直子, 正井久雄
- Organizer
  BMB2007(第30回日本分子生物学会年会・第80回日本生化学会大会合同大会)
- Place of Presentation
  横浜パシフィコ(一般口頭発表)
- Year and Date
  2007-12-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570169
[Presentation] Roles of human Tipin in DNA replication and checkpoint.2006
- Author(s)
  Naoko Yoshizawa and Hisao Masai
- Organizer
  18th workshop of DNA replication and chromosome segregation
- Place of Presentation
  Atami KKR hotel
- Year and Date
  2006-10-31
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570169
[Presentation] DNA複製フォーク安定化因子Tim,Tipinの機能解析2006
- Author(s)
  吉沢直子, 正井久雄
- Organizer
  第18回DNA複製・分配ワークショップ
- Place of Presentation
  KKRホテル熱海
- Year and Date
  2006-10-31
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570169
[Presentation] 染色体DNA複製プログラムの制御機構と起源・進化
- Author(s)
  正井久雄、田中卓、加納豊、山崎聡志、松本清治、吉沢直子、松嶋夢叶
- Organizer
  第２回細胞周期制御と細胞運命　シンポジウム
- Place of Presentation
  浜松（静岡）
- Year and Date
  2014-02-13 – 2014-02-14
- Invited
- Data Source
  KAKENHI-PROJECT-23247031
[Presentation] Chromatin architecture that regulates replication timing of eukaryotic chromosomes
- Author(s)
  Hisao Masai, Yutaka Kanoh, Satoshi Yamazaki, Motoshi Hayano, Naoko Yoshizawa, Kenji Moriyama, Yumeka Matsushima, Naoko Kakusho, Rino Fukatsu
- Organizer
  第86回日本生化学会大会事務局インターナショナルセッション『Assembly and architecture of protein complexes regulating inheritance and stable maintenance of genome』
- Place of Presentation
  パシフィコ横浜（神奈川）
- Year and Date
  2013-09-11 – 2013-09-13
- Invited
- Data Source
  KAKENHI-PROJECT-23247031
[Presentation] Rif1: a potential global regulator of DNA replication, DNA repair, and recombination
- Author(s)
  正井久雄、山崎聡志、Lai Mongsing、Foiani Marco、吉沢直子、加納豊、松本清治、森山賢治、覺正直子、深津理乃、松嶋夢叶、河野暢明、Renard-Guillet Claire
- Organizer
  第36回（2013年）日本分子生物学会年会，ワークショップ『DNA二重鎖切断のend-resectionと修復機構の選択・制御』
- Place of Presentation
  神戸ポートアイランド（兵庫）
- Year and Date
  2013-12-03 – 2013-12-06
- Invited
- Data Source
  KAKENHI-PROJECT-23247031
[]

1. MASAI Hisao (40229349)

# of Collaborated Projects: 4 results

# of Collaborated Products: 14 results
2. TAKAI Yuko (90332270)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. MORIYAMA Kenji (00250217)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
4. SHINMOTO Micie (20216237)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. MIYATAKE Syouitirou (30239420)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. MATSUMOTO Seiji (40190532)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
7. ISHII Ai (80124436)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. TANAKA Taku (80425686)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. KANO Yutaka (90450593)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. ODA Masako (50399474)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. ITO Sayuri (60462777)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. HAYANO Motoshi (30593644)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. KAKUSHO Naoko (30599593)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. TSURIMOTO Toshiki (30163885)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. SIRAKATA Masaki (70251551)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. HARA Yuichiro (70709708)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. 林田敏郎 (20342925)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. TAMAI Katsuyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

yoshizawa naoko 吉沢 直子 (須賀田 直子)

吉沢 直子 ヨシザワ ナオコ(スガタナオコ)

須賀田直子

YOSHIZAWA Naoko 吉沢 直子

SUGATA Naoko 須賀田 直子

吉沢 直子(須賀田直子) ヨシザワ ナオコ

須賀田 直子

Research Projects

Research Products

Co-Researchers

Elucidation of de novo gene birth and pseudogenization processes via reconstruction of ancestral transcriptional regulation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of Rif1 in regulating muticopy gene cluster and super state of pluripotent stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the functions and structures of Cdc7 kinase, essential for initiation of DNA replication

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of the replication stress response of variable replication fork complexesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms of genomic stability maintenance by replication scaffold protein, AND-1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of DNA replication program in mammalian cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of fork protection complex and cdc7 kinase in fork-stabilization and replication checkpointPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

遺伝子治療のための染色体複製起点由来のエピゾームベクターの開発に関する研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Enzymatic analyses of eukaryotic chromosomal DNA replication using the Epstein Barr Virus-derived oriP replicon

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] The Initiation of DNA Replication in Eukaryotes2016

Author(s)

Total Pages

Publisher

Data Source

[Book] Methods in Molecular Biology2014

Author(s)

Publisher

Data Source

[Journal Article] Oligomer formation and G-quadruplex binding by purified murine Rif1 protein, a key organizer of higher-order chromatin architecture2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Telomere-binding factors in the regulation of DNA replication2017

Author(s)

yoshizawa naoko 吉沢直子 (須賀田直子)

吉沢直子ヨシザワナオコ(スガタナオコ)

YOSHIZAWA Naoko 吉沢直子

SUGATA Naoko 須賀田直子

吉沢直子(須賀田直子) ヨシザワナオコ

須賀田直子