KAWABATA Kenichi 川端健一

Researcher Number	30345706
Other IDs
Affiliation (Current)	2025: 山梨大学, 大学院総合研究部, 特任講師
Affiliation (based on the past Project Information) *help	2014 – 2016: 山梨大学, 総合研究部, 講師 2011 – 2013: 山梨大学, 医学部附属病院, 講師 2010: 山梨大学, 医学部・附属病院, 講師 2008 – 2009: 山梨大学, 医学部附属病院, 講師 2007: 山梨大学, 大学院・医学工学総合研究部, 助教 2005: 山梨大学, 大学院医学工学総合研究部, 助手 2003 – 2005: 山梨大学, 大学院・医学工学総合研究部, 助手
Review Section/Research Field	Except Principal Investigator Circulatory organs internal medicine / Biological Sciences / Cardiovascular medicine / Laboratory medicine
Keywords	Except Principal Investigator 心血管病 / 虚血性心疾患 / バイオマーカー / 内皮機能 / Remote conditioning / 炎症 / ノックアウトマウス / 心筋梗塞 / 血管内皮細胞 / 遺伝子多型 … More / グルタチオン / NO / 酸化ストレス / Carotid plaque / Metabolic syndrome / Endothelial dysfunction / Cardiovascular diseases / Remnant lipoprotein / 動脈硬化 / 脳梗塞 / 中性脂肪 / 高脂血症 / 頚動脈粥腫 / メタボリックシンドローム / 内皮細胞機能障害 / レムナントリポ蛋白 / 拡張不全 / remote conditioning / 心不全 / ＲＮＡ診断 / 循環器病学 / RNA / 不安定プラーク / RNA診断 / 血管内皮機能 / DES / TNF / 受容体 / ホスホリパーゼA2 / 分泌型ホスホリパーゼA2受容体 / 好中球 / 脂質メディエーター / 分泌型ホスホリパーゼA Less

Search for RNA biomerker of cardiovascular disease
- Principal Investigator
  
  NAKAMURA Kazuto
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  University of Yamanashi
Effects of remote ischemic conditioning on dilatory function in patients with heart failure.
- Principal Investigator
  
  NAKAMURA Takamitsu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  University of Yamanashi
Effects of remote ischemic conditioning on coronary endothelial vasomotor function in patients treated with drug eluting stents
- Principal Investigator
  
  NAKAMURA Takamitsu
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  University of Yamanashi
A study of role of phospholipase A2 receptor in pathogenosis ofcardiovascular diseases and development of new drug for cardiovascular diseases
- Principal Investigator
  
  KUGIYAMA Kiyotaka
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  University of Yamanashi
A study of role of phospholipase A2 in pathogenosis of cardiovascular diseases and development of new drug for cardiovascular diseases
- Principal Investigator
  
  KUGIYAMA Kiyotaka
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  University of Yamanashi
酸化ストレス関連分子の遺伝子多型を基盤とする冠攣縮の病態解明と診断・治療法の開発
- Principal Investigator
  
  久木山清貴
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Yamanashi
酸化ストレス関連分子の遺伝子多型を基盤とする冠攣縮の病態解明と診断・治療法の開発
- Principal Investigator
  
  KUGIYAMA Kiyotaka
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Yamanashi
Clinical significance of remnant lipoproteinemia as a therapeutic target of cardiovascular diseases
- Principal Investigator
  
  KUGIYAMA Kiyotaka
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  University of Yamanashi

All 2015 2014 2013 2012 2011 2010 2009 2008 2007

All Journal Article Presentation

[Journal Article] Assessment of carotid plaque neovascularization using quantitative analysis of contrast-enhanced ultrasound imaging is useful for risk stratification in patients with coronary artery disease.2015
- Author(s)
  Nakamura J, Nakamura T, Deyama J, Fujioka D, Kawabata K, Obata JE, Watanabe K, Watanabe Y, Kugiyama K.
- Journal Title
  
  Int J Cardiol.
  
  Volume: 195 Pages: 113-119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461060
[Journal Article] Combined assessement of flow-mediated dilation of the brachial artery and brachial-ankle pulse wave velocity improves the prediction of future coronary events in patients with chronic coronary artery disease.2014
- Author(s)
  Sugamata W
- Journal Title
  
  J Cardiol
  
  Volume: 64(3) Issue: 3 Pages: 179-84
- DOI
  10.1016/j.jjcc.2014.01.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461059, KAKENHI-PROJECT-26461060
[Journal Article] Water quality monitoring and risk assessment by simultaneous multi-pathogen quantification2014
- Author(s)
  Satoshi Ishii, Takamitsu Nakamura, Shuji Ozawa, Ayano Kobayashi, Daisuke Sano, Satoshi Okabe
- Journal Title
  
  Environmental Science and Technology
  
  Volume: 48(9) Issue: 9 Pages: 4744-4749
- DOI
  10.1021/es500578s
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26303011, KAKENHI-PROJECT-26461060
[Journal Article] Chronicdepletion of glutathione exacerbatesventricular remodelling and dysfunctionin the pressure-overloaded heart2013
- Author(s)
  Watanabe Y, Watanabe K, Kobayashi T,Saito Y, Fujioka D, Nakamura T, Obata JE,Kawabata K, Mishina H, Kugiyama K
- Journal Title
  
  Cardiovasc Res
  
  Volume: Vol. 97, No. 2 Pages: 282-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390158
[Journal Article] Group X secretory PLA2 in neutrophilsplays a pathogenic role in abdominalaortic aneurysms in mice2012
- Author(s)
  Watanabe K, Fujioka D, Saito Y, NakamuraT, Obata JE, Kawabata K, Watanabe Y,Mishina H, Tamaru S, Hanasaki K, KugiyamaK
- Journal Title
  
  Am J Physiol Heart Circ Physiol
  
  Volume: Vol.302, No. 1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390158
[Journal Article] Disruption of group IVAcytosolic phospholipase A(2) attenuatesmyocardial ischemia-reperfusion injurypartly through inhibition ofTNF-α-mediated pathway2012
- Author(s)
  Saito Y, Watanabe K, Fujioka D, NakamuraT, Obata JE, Kawabata K, Watanabe Y,Mishina H, Tamaru S, Kita Y, Shimizu T,Kugiyama K
- Journal Title
  
  Am J PhysiolHeart Circ Physiol
  
  Volume: Vol.302,No.10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390158
[Journal Article] Group V secretoryphospholipase A2 plays a pathogenic rolein myocardial ischaemia-reperfusioninjury2011
- Author(s)
  Yano T, Fujioka D, Saito Y, KobayashiT, Nakamura T, Obata JE, Kawabata K,Watanabe K, Watanabe Y, Mishina H, TamaruS, Kugiyama K
- Journal Title
  
  Cardiovasc Res
  
  Volume: Vol. 90,No. 2 Pages: 335-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390158
[Journal Article] Mice lacking the glutamate-cysteine ligase modifier subunit are susceptible to myocardial ischaemia-reperfusion injury.2010
- Author(s)
  Kobayashi T, Watanabe Y, Saito Y, Fujioka D, Nakamura T, Obata JE, Kitta Y, Yano T, Kawabata K, Watanabe K, Mishina H, Ito S, Kugiyama K.
- Journal Title
  
  Cardiovasc Res. 85,4
  
  Pages: 785-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390209
[Journal Article] Inhibition of secretory hospholipase A2 activity attenuates lipopolysaccharide-induced acute lung injury in a mouse model.2010
- Author(s)
  Sato R, Yamaga S, Watanabe K, Hishiyama S, Kawabata K, Kobayashi T, Fujioka D, Saito Y, Yano T, Watanabe K, Watanabe Y, Ishihara H, Kugiyama K.
- Journal Title
  
  Exp Lung Res. 36,4
  
  Pages: 191-200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390209
[Journal Article] Inhibition of secretory phospholipase A2 activity attenuates acute cardiogenic pulmonary edema induced by isoproterenol infusion in mice after myocardial infarction2010
- Author(s)
  Kawabata K, et al
- Journal Title
  
  J Cardiovasc Pharmacol.
  
  Volume: 56 Pages: 369-378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390158
[Journal Article] Rapid improvement of carotid plaque echogenicity within 1 month of pioglitazone treatment in patients with acute coronary syndrome.2009
- Author(s)
  Hirano M, Nakamura T, Kitta Y, Yano T, Kobayashi T, Sano K, Fujioka D, Saito Y, Kodama Y, Kawabata K, Nakamura K, Obata JE, Kugiyama K.
- Journal Title
  
  Atherosclerosis. 203,2
  
  Pages: 483-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390209
[Journal Article] Persistent impairment of endothelial vasomotor function has a negative impact on outcome in patients with coronary artery disease.2009
- Author(s)
  Kitta Y, Obata JE, Nakamura T, Hirano M, Kodama Y, Fujioka D, Saito Y, Kawabata K, Sano K, Kobayashi T, Yano T, Nakamura K, Kugiyama K.
- Journal Title
  
  J Am Coll Cardiol. 53,4
  
  Pages: 323-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390209
[Journal Article] High serum levels of remnant lipoproteins predict ischemic stroke in patients with metabolic syndrome and mild carotid atherosclerosis.2009
- Author(s)
  Nakamura T, Obata JE, Takano H, Kawabata K, Sano K, Kobayashi T, Fujioka D, Saito Y, Yano T, Kugiyama K.
- Journal Title
  
  Atherosclerosis. 202,1
  
  Pages: 234-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390209
[Journal Article] Reduction in myocardial ischemia/reperfusion injury in group X secretory phospholipase A2-deficient mice.2008
- Author(s)
  Fujioka D, Saito Y, Kobayashi T, Yano T, Tezuka H, Ishimoto Y, Suzuki N, Yokota Y, Nakamura T, Obata JE, Kanazawa M, Kawabata K, Hanasaki K, Kugiyama K.
- Journal Title
  
  Circulation. 117,23
  
  Pages: 2977-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390209
[Journal Article] Sirolimus-eluting stent implantation aggravates endothelial vasomotor dysfunction in the infarct-related coronary artery in patients with acute myocardial infarction.2007
- Author(s)
  Obata JE, Kitta Y, Takano H, Kodama Y, Nakamura T, Mende A, Kawabata K, Saitoh Y, Fujioka D, Kobayashi T, Yano T, Kugiyama K.
- Journal Title
  
  J Am Coll Cardiol. 50,14
  
  Pages: 1305-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390209
[Presentation] Chronic Depletion of GlutathioneExacerbates Ventricular Remodeling andDysfunction in Pressure Overloaded Heartin Mice Lacking the Glutamate-CysteineLigase Modifier Subunit2012
- Author(s)
  Yosuke Watanabe,Kazuhiro Watanabe, Tsuyoshi Kobayashi,Yukio Saito, Daisuke Fujioka, TakamitsuNakamura, Jun-ei Obata, Kenichi Kawabata,Hideto Mishina, and Kiyotaka Kugiyama
- Organizer
  米国心臓病学会
- Place of Presentation
  ロサンゼルス、アメリカ
- Data Source
  KAKENHI-PROJECT-22390158
[Presentation] Group X Secretory Phospholipase A2 inNeutrophils Plays a Pathogenic Role inAbdominal Aortic Aneurysms in Mice2011
- Author(s)
  Kazuhiro Watanabe, Daisuke Fujioka, YukioSaito, Takamitsu Nakamura, Jun-ei Obata,Kenichi Kawabata, Yosuke Watanabe, HidetoMishina, Shun Tamaru, and KiyotakaKugiyama
- Organizer
  米国心臓病学会
- Place of Presentation
  オーランド、アメリカ
- Data Source
  KAKENHI-PROJECT-22390158
[Presentation] Group V Secretory Phospholipase A2Plays a Role in Myocardial IschemiaReperfusion Injury Through CytosolicPhospholipase A22010
- Author(s)
  Toshiaki Yano, KenichiKawabata, Yukio Saito, Kazuhiro Watanabe,Yosuke Watanabe, Hideto Mishina, ShunTamaru, Junei Obata, and Kiyotaka Kugiyama
- Organizer
  米国心臓病学会
- Place of Presentation
  シカゴ、アメリカ
- Data Source
  KAKENHI-PROJECT-22390158
[Presentation] Reduction in Myocardial Ischemia-reperfusion Injury in Group IV Cytosolic Phospholipase A2-deficient Mice Partly Due to Inhibition of TNFα-mediated Pathway to Cell Injury.2009
- Author(s)
  Yukio Saito; Yousuke Watanabe; Hideto Mishina; Kazuhiro Watanabe; Toshiaki Yano; Tsuyoshi Kobayashi; Jun-ei Obata; Ken-ichi Kawabata; Takao Shimizu; Kiyotaka Kugiyama
- Organizer
  American Heart Association Scientific Sessions.
- Place of Presentation
  Orlando.
- Data Source
  KAKENHI-PROJECT-19390209
[Presentation] Reduction in Myocardial Ischemia-reperfusion Injury in Group V Secretory Phospholipase A2-deficient Mice.2009
- Author(s)
  Toshiaki Yano; Keni-chi Kawabata; Yukio Saito; Tsuyoshi Kobayashi; Ryota Sato; Kazuhiro Watanabe; Yosuke Watanabe; Hideto Mishina; Jun-ei Obata; Kiyotaka Kugiyama
- Organizer
  American Heart Association Scientific Sessions.
- Place of Presentation
  Orlando.
- Data Source
  KAKENHI-PROJECT-19390209
[Presentation] Inhibition of Secretory Phospholipase A2 Activity Attenuates Acute Cardiogenic Pulmonary Congestion Induced by Isoproterenol Infusion in Mice with Post-Myocardial Infarction.2008
- Author(s)
  Kenichi Kawabata, Tsuyoshi Kobayashi, Yousuke Watanabe, Kazuhiro Watanabe, Toshiaki Yano, Ryota Sato, Yukio Saito, Kazuto Nakamura, Kiyotaka Kugiyama
- Organizer
  American Heart Association Scientific Sessions
- Place of Presentation
  New Orleans
- Data Source
  KAKENHI-PROJECT-19390209
[Presentation] Group X Secretory Phospholipase A2 has a Critical Role in Neutrophils Activation and Myocardial Ischemia-reperfusion Injury in Mice.2007
- Author(s)
  Daisuke Fujioka, Kenichi Kawabata, Yoshikazu Ishimoto, Noriko Suzuki, Kohji Hansaki, Ryota Sato, Toshiaki Yano, Tsuyoshi Kobayashi, Yukio Saito, Masaki Kanazawa, Kiyotaka Kugiyama
- Organizer
  American Heart Association Scientific Sessions
- Place of Presentation
  Orlando
- Data Source
  KAKENHI-PROJECT-19390209

1. KUGIYAMA Kiyotaka (00225129)

# of Collaborated Projects: 7 results

# of Collaborated Products: 19 results
2. OBATA Jun-ei (60362076)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
3. FUJIOKA Daisuke (70377513)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
4. NAKAMURA Takamitsu (60377512)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
5. UMETANI Ken (40262654)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. TEZUKA Hideo (70155456)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. SAITO Yukio (50377511)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
8. WATANABE Kazuhiro (50535549)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
9. NAKAMURA Kazuto (30456488)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
10. 長田満 (40311691)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. KOBAYASHI Tsuyoshi (40402052)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
12. WATANABE Yohsuke (90535551)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
13. MISHINA Hideto (70568021)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
14. YANO Toshiaki (60456449)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. KITTA Yoshinobu (10377509)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. TAKANO Hajime (20362064)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 比江島欣慎 (00313809)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 杉山正悟 (90274711)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. SANO Daisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 石井聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KAWABATA Kenichi 川端 健一

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[Journal Article] Assessment of carotid plaque neovascularization using quantitative analysis of contrast-enhanced ultrasound imaging is useful for risk stratification in patients with coronary artery disease.2015

Author(s)

Journal Title

Data Source

[Journal Article] Combined assessement of flow-mediated dilation of the brachial artery and brachial-ankle pulse wave velocity improves the prediction of future coronary events in patients with chronic coronary artery disease.2014

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DOI

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[Journal Article] Water quality monitoring and risk assessment by simultaneous multi-pathogen quantification2014

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DOI

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[Journal Article] Chronicdepletion of glutathione exacerbatesventricular remodelling and dysfunctionin the pressure-overloaded heart2013

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Journal Title

Data Source

[Journal Article] Group X secretory PLA2 in neutrophilsplays a pathogenic role in abdominalaortic aneurysms in mice2012

Author(s)

Journal Title

Data Source

[Journal Article] Disruption of group IVAcytosolic phospholipase A(2) attenuatesmyocardial ischemia-reperfusion injurypartly through inhibition ofTNF-α-mediated pathway2012

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[Journal Article] Group V secretoryphospholipase A2 plays a pathogenic rolein myocardial ischaemia-reperfusioninjury2011

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[Journal Article] Mice lacking the glutamate-cysteine ligase modifier subunit are susceptible to myocardial ischaemia-reperfusion injury.2010

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[Journal Article] Inhibition of secretory hospholipase A2 activity attenuates lipopolysaccharide-induced acute lung injury in a mouse model.2010

Author(s)

KAWABATA Kenichi 川端健一