Nishiguchi Koji 西口康二

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KOJI Nishiguchi 西口康二

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Researcher Number	30447825
Other IDs
Affiliation (Current)	2025: 名古屋大学, 医学系研究科, 教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 名古屋大学, 医学系研究科, 教授 2021: 東北大学, 医学系研究科, 准教授 2016 – 2019: 東北大学, 医学系研究科, 准教授 2014 – 2016: 東北大学, 医学(系)研究科(研究院), 准教授 2007 – 2011: 名古屋大学, 医学部附属病院, 助教 2007 – 2008: Nagoya University, 医学部・附属病院, 助教
Review Section/Research Field	Principal Investigator Ophthalmology / Basic Section 56060:Ophthalmology-related Except Principal Investigator Basic Section 56060:Ophthalmology-related / Ophthalmology / Basic Section 52040:Radiological sciences-related
Keywords	Principal Investigator 網膜変性 / 視細胞 / 網膜 / ゲノム編集 / 網膜色素変性 / 遺伝子治療 / 神経科学 / 網膜発生 / 毛様体上皮 / アデノ随伴ウイルス … More / リンパ球 / ウィルス / 脳・神経 / トランスレーショナルリサーチ / 細胞・組織 / 視覚再建 / 視覚領野 / 可塑性 / 免疫 / 遺伝子 / 遺伝 / 自己抗体 / 自己免疫疾患 / 網膜色素変性症 / 糖尿病網膜症 / 血管内皮成長因子 / ヘパラン硫酸 … More Except Principal Investigator 網膜色素変性 / アデノ随伴ウイルス / 遺伝子治療 / ゲノム編集 / 緑内障 / 病因遺伝子検索 / カニクイザル / 疾患モデル動物 / Glymphatic system / 磁気共鳴画像 / メニエール病 / 神経変性疾患 / 病院遺伝子検索 / 病因遺伝子解析 / 遺伝子編集 / 網膜 / in vivoイメージング / RGC / E-SARE / 網膜神経節細胞 / CAGE解析 / CAGE法 / バイオマーカー / RNA / 網膜電図 / トランスジェニックウサギ / 骨髄由来細胞 / 網膜変性 / ヘパラン硫酸 / 加齢黄斑変性 / 骨髄幹細胞 / 小胞体ストレス / 網膜静脈分枝閉塞症 / 脈絡膜新生血管 / 脈絡膜 / ヘパリン / 血管内皮増殖因子 / 加齢黄斑変性症 / 光干渉断層計 / 未熟児網膜症 / 眼内移植 / 移植 / 神経栄養因子 / 遺伝性眼底疾患 / 高分子半透膜 / カプセル化細胞 Less

網膜色素変性治療のためのゲノム編集遺伝子治療ベクタープラットフォームの開発
- Principal Investigator
  
  藤田幸輔
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Nagoya University
革新的なゲノム編集遺伝子治療実現のための包括的基盤形成Principal Investigator
- Principal Investigator
  
  西口康二
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Nagoya University
Early detection of pre-symptomatic conditions through evaluation of vascular permeability and waste excretion function in the brain and sensory organs
- Principal Investigator
  
  長縄慎二
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Nagoya University
網膜色素変性を自然発症するカニクイザルの繁殖と治療法開発への応用
- Principal Investigator
  
  池田康博
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  University of Miyazaki
Development of highly efficient genome editing gene therapy for retinitis pigmentosa
- Principal Investigator
  
  Fujita Kosuke
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Nagoya University
Development of expression analysis for retinitis pigmentosa causative genes using peripheral blood by epigenome editingPrincipal Investigator
- Principal Investigator
  
  Nishiguchi Koji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Nagoya University
The study of determining the disease pathogenesis and developing the attractive animal disease model using cynomolgus monkeys with retinitis pigmentosa
- Principal Investigator
  
  Ikeda Yasuhiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  University of Miyazaki
Development of a novel CRISPR-Cas9 vector for functional analysis of retinal disease-related genes
- Principal Investigator
  
  Fujita Kosuke
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Nagoya University
  Tohoku University
Comparison of plasticity between rod and cone visual pathwaysPrincipal Investigator
- Principal Investigator
  
  Nishiguchi Koji
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Tohoku University
In vivo imaging of retinal ganglion cell function using adeno-associated virus
- Principal Investigator
  
  Nakazawa Toru
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Ophthalmology
- Research Institution
  Tohoku University
Search for genetic causes and autoantibodies of retinitis pigmentosa sine pigmentoPrincipal Investigator
- Principal Investigator
  
  Nishiguchi Koji
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Ophthalmology
- Research Institution
  Tohoku University
Research for blood RNA marker predicting prognosis of glaucoma focusing on the early and individualized medicine.
- Principal Investigator
  
  Nakazawa Toru
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Tohoku University
眼内炎症における補体系と眼内液中硫酸化グリコサミノグリカンの役割の検討Principal Investigator
- Principal Investigator
  
  西口康二
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Nagoya University
Regulatory mechanisms of neuronal regeneration in the retina and role of the pars plana.Principal Investigator
- Principal Investigator
  
  NISHIGUCHI Koji
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Nagoya University
Elucidating the molecular pathology and development of treatment modalities for ischemic retinopathies
- Principal Investigator
  
  TERASAKI Hiroko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Nagoya University
Intraocular implantation of encapsulated neurotrophic factor-secreting cell
- Principal Investigator
  
  NAKAMURA Makoto
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Nagoya University
The analyses of photoreceptor regeneration from cilio-retinal stem cells using flatmount techniquePrincipal Investigator
- Principal Investigator
  
  NISHIGUCHI Koji
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Nagoya University

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All Journal Article Presentation Patent

[Journal Article] Glymphatic system impairment in nonathlete older male adults who played contact sports in their youth associated with cognitive decline: A diffusion tensor image analysis along the perivascular space study2023
- Author(s)
  Morita Yuichi、Kamagata Koji、Andica Christina、Takabayashi Kaito、Kikuta Junko、Fujita Shohei、Samoyeau Thomas、Uchida Wataru、Saito Yuya、Tabata Hiroki、Naito Hitoshi、Someya Yuki、Kaga Hideyoshi、Tamura Yoshifumi、Miyata Mari、Akashi Toshiaki、Wada Akihiko、Taoka Toshiaki、Naganawa Shinji、et al.
- Journal Title
  
  Frontiers in Neurology
  
  Volume: 14 Pages: 1100736-1100736
- DOI
  10.3389/fneur.2023.1100736
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07563, KAKENHI-PROJECT-20K16737, KAKENHI-PROJECT-21K17644, KAKENHI-PROJECT-19K17244, KAKENHI-PROJECT-23K27545
[Journal Article] Glymphatic System Dysfunction in Myelin Oligodendrocyte Glycoprotein Immunoglobulin G Antibody Associated Disorders: Association with Clinical Disability2023
- Author(s)
  Hagiwara Akifumi、Tomizawa Yuji、Hoshino Yasunobu、Yokoyama Kazumasa、Kamagata Koji、Sekine Towa、Takabayashi Kaito、Nakaya Moto、Maekawa Tomoko、Akashi Toshiaki、Wada Akihiko、Taoka Toshiaki、Naganawa Shinji、Hattori Nobutaka、Aoki Shigeki
- Journal Title
  
  American Journal of Neuroradiology
  
  Volume: 45 Issue: 1 Pages: 66-71
- DOI
  10.3174/ajnr.a8066
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07563, KAKENHI-PROJECT-23K27545
[Journal Article] A hypomorphic variant in EYS detected by genome-wide association study contributes toward retinitis pigmentosa.2021
- Author(s)
  Nishiguchi KM, Miya F, Mori Y, Fujita K, Akiyama M, Kamatani T, Koyanagi Y, Sato K, Takigawa T, Ueno S, Tsugita M, Kunikata H, Cisarova K, Nishino J, Murakami A, Abe T, Momozawa Y, Terasaki H, Wada Y, Sonoda KH, Rivolta C, Tsunoda T, Tsujikawa M, Ikeda Y, Nakazawa T.
- Journal Title
  
  Commun Biol
  
  Volume: 4 Issue: 1 Pages: 140-140
- DOI
  10.1038/s42003-021-01662-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09989, KAKENHI-PROJECT-17K11448, KAKENHI-PROJECT-20K09765, KAKENHI-PROJECT-21K19570
[Journal Article] In vivo imaging of the light response in mouse retinal ganglion cells based on a neuronal activity-dependent promoter2020
- Author(s)
  Fujita Kosuke、Nishiguchi Koji M.、Sato Kota、Nakagawa Yurika、Nakazawa Toru
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 521 Issue: 2 Pages: 471-477
- DOI
  10.1016/j.bbrc.2019.10.155
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09395
[Journal Article] Single AAV-mediated mutation replacement genome editing in limited number of photoreceptors restores vision in mice2020
- Author(s)
  Nishiguchi Koji M.、Fujita Kosuke、Miya Fuyuki、Katayama Shota、Nakazawa Toru
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 482-482
- DOI
  10.1038/s41467-019-14181-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09395
[Journal Article] Retained plsticity and substantial recovery of rod-mediated visual acuity at the visual cortex in blind adult mice with retinal dystrophy2018
- Author(s)
  Nishiguchi KM, Fujita K, Tokashiki N, Komamura H, Takemoto-Kimura S, Okuno H, Bito H, Nakazawa T.
- Journal Title
  
  Mol Ther
  
  Volume: 26 Issue: 10 Pages: 2397-2406
- DOI
  10.1016/j.ymthe.2018.07.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04258, KAKENHI-PROJECT-16K11315, KAKENHI-PROJECT-16H06279
[Journal Article] Transcriptome profiling of the rat retina after optic nerve transection.2016
- Author(s)
  Masayuki Yasuda, Yuji Tanaka, Kazuko Omodaka, Koji M. Nishiguchi, Orie Nakamura, Satoru Tsuda, Toru Nakazawa
- Journal Title
  
  Scientific reports
  
  Volume: 6 Issue: 1
- DOI
  10.1038/srep28736
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293372
[Journal Article] Brimonidine Enhances the Electrophysiological Response of Retinal Ganglion Cells through the Trk-MAPK/ERK and PI3K Pathways in Axotomized Eyes2016
- Author(s)
  Masayoshi Yukita, Kazuko Omodaka, Shigeki Machida, Masayuki Yasuda1, Kota Sato, Kazuichi Maruyama, Koji M Nishiguchi, Toru Nakazawa
- Journal Title
  
  Current Eye Research
  
  Volume: 未定
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26893018
[Journal Article] Axial Spondylometaphyseal Dysplasia Is Caused by C21orf2 Mutations2016
- Author(s)
  Zheng Wang , Aritoshi Iida , Noriko Miyake , Koji M. Nishiguchi, Kosuke Fujita, Toru Nakazawa, Abdulrahman Alswaid, Mohammed A. Albalwi, Ok-Hwa Kim, Tae-Joon Cho, Gye-Yeon Lim, Bertrand Isidor, Albert David, Cecilie F. Rustad, Else Merckoll, Jostein Westvik, Eva-Lena Stattin, Giedre Grigelioniene
- Journal Title
  
  PloS ONE
  
  Volume: 11 Issue: 3 Pages: e0150555-e0150555
- DOI
  10.1371/journal.pone.0150555
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26893018, KAKENHI-PROJECT-25293235
[Journal Article] Brimonidine Enhances the Electrophysiological Response of Retinal Ganglion Cells through the Trk-MAPK/ERK and PI3K Pathways in Axotomized Eyes.2016
- Author(s)
  Masayoshi Yukita, Kazuko Omodaka, Shigeki Machida, Masayuki Yasuda, Kota Sato, Kazuichi Maruyama, Koji M Nishiguchi, Toru Nakazawa
- Journal Title
  
  Current Eye Research
  
  Volume: 未定
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293372
[Journal Article] In vivo cellular imaging of various stress/response pathways using AAV following axonal injury in mice2015
- Author(s)
  Kosuke Fujita, Koji M Nishiguchi, Yu Yokoyama, Yusuke Tomiyama, Satoru Tsuda, Masayuki Yasuda, Shigeto Maekawa & Toru Nakazawa
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 3 Pages: 18141-18141
- DOI
  10.1371/journal.pone.0153121
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26893018
[Journal Article] Molecular, anatomical and functional changes in the retinal ganglion cells after optic nerve crush in mice2015
- Author(s)
  Yukita M, Machida S, Nishiguchi KM, Tsuda S, Yokoyama Y, Yasuda M, Maruyama K, Nakazawa T.
- Journal Title
  
  Doc Ophthalmol.
  
  Volume: 130 Issue: 2 Pages: 149-156
- DOI
  10.1007/s10633-014-9478-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26893018, KAKENHI-PROJECT-26462677, KAKENHI-PROJECT-26293372
[Journal Article] In vivo cellular imaging of various stress/response pathways using AAV following axonal injury in mice.2015
- Author(s)
  Kosuke Fujita, Koji M Nishiguchi, Yu Yokoyama, Yusuke Tomiyama, Satoru Tsuda, Masayuki Yasuda, Shigeto Maekawa, Toru Nakazawa
- Journal Title
  
  Scientific reports
  
  Volume: 5 Issue: 1 Pages: 18141-18141
- DOI
  10.1038/srep18141
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293372
[Journal Article] The roles of vitreal macrophages and circulating leukocytes in retinal neovascularization.2011
- Author(s)
  Kataoka K, Nishiguchi KM, Kaneko H, van Rooijen N, Kachi S, Terasaki H.
- Journal Title
  
  Invest Ophthalmol Vis Sci. 52
  
  Pages: 1431-1438
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791676
[Journal Article] Suppression of choroidal neovascularization and quantitative and qualitative inhibition of VEGF and CCL2 by heparin.2011
- Author(s)
  Tomida D, Nishiguchi KM, Kataoka K, Yasuma TR, Iwata E, Uetani R, Kachi S, Terasaki H.
- Journal Title
  
  Invest Ophthalmol Vis Sci. in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791676
[Journal Article] Regulation of pathologic retinal angiogenesis and inhibition of VEGF-VEGFR2 binding b soluble heparan sulfate.2010
- Author(s)
  Nishiguchi KM
- Journal Title
  
  PLoS ONE
  
  Volume: 20;5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390448
[Journal Article] Regulation of pathologic retinal angiogenesis in mice and inhibition of VEGF-VEGFR2 binding by soluble heparan sulfate.2010
- Author(s)
  Nishiguchi KM
- Journal Title
  
  PLoS One
  
  Volume: 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791676
[Journal Article] Elevated C-reactive protein levels and ARMS2/HTRA1 gene variants in subjects without age-related macular degeneration2010
- Author(s)
  Yasuma TR, Nakamura M, Nishiguchi KM, Kikuchi M, Kaneko H, Niwa T, Hamajima N, Terasaki H
- Journal Title
  
  Mol Vis. 16
  
  Pages: 2923-2930
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791676
[Journal Article] TRPM1 mutations are associated with the complete form of congenital stationary night blindness.2010
- Author(s)
  Nakamura M, Sanuki R, Yasuma TR, Onishi A, Nishiguchi KM, Koike C, Kadowaki M, Kondo M, Miyake Y, Furukawa T.
- Journal Title
  
  Mol Vis. 16
  
  Pages: 425-437
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791676
[Journal Article] Regulation of pathologic retinal angiogenesis and inhibition of VEGF-VEGFR2 binding by soluble heparan sulfate.2010
- Author(s)
  Nishiguchi KM, Terasaki H, 他3名
- Journal Title
  
  PLoS ONE 20 5(10)
- Data Source
  KAKENHI-PROJECT-20390448
[Journal Article] Regulation of pathologic retinal angiogenesis and inhibition of VEGF-VEGFR2 binding by soluble heparan sulfate.2010
- Author(s)
  Nishiguchi KM, Kataoka K, Kachi S, Komeima K, Terasaki H
- Journal Title
  
  PLoS ONE. 5
  
  Pages: 13493-13493
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791676
[Journal Article] Generation of immature retinal neurons from proliferating cells in the pars plana after retinal histogenesisin mice with retinal degeneration2009
- Author(s)
  Nishiguchi KM., et al
- Journal Title
  
  Mol Vis 15
  
  Pages: 187-199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390448
[Journal Article] Generation of immature retinal neurons from proliferating cells in the pars plana after retinal histogenesis in mice with retinal degeneration2009
- Author(s)
  Nishiguchi KM
- Journal Title
  
  Mol Vis 15
  
  Pages: 187-199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791263
[Journal Article] Generation of immature retinal neurons from proliferating cells in the pars plana after retinal histogenesis in mice with retinal degeneration.2009
- Author(s)
  Nishiguchi KM
- Journal Title
  
  Mol Vis. 15
  
  Pages: 187-199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791676
[Journal Article] Generation of immature retinal neurons from proliferating cells in the pars plan after retinal histogenesis in mice with retinal degeneration.2009
- Author(s)
  Nishiguchi KM, Terasaki H, 他3名
- Journal Title
  
  Mol Vis 15(2)
  
  Pages: 187-199
- Data Source
  KAKENHI-PROJECT-20390448
[Journal Article] Generation of immature retinal neurons from proliferating cells in the pars plana after retinal histogenesis in mice with retinal degeneration2009
- Author(s)
  Nishiguchi KM, Kaneko H, Nakamura M, Kachi S, Terasaki H
- Journal Title
  
  Mol Vis 15
  
  Pages: 187-199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791263
[Journal Article] Identification of photoreceptor precursors in the pars plana during ocular development and after retinal injury2008
- Author(s)
  Nishiguchi KM, Kaneko H, Nakamura M, Kachi S, et.al.(他1名)
- Journal Title
  
  Invest Ophthalmol Vis Sci 49
  
  Pages: 422-428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592013
[Journal Article] Retardation of Photoreceptor Degeneration in the Detached Retina of rd1 Mouse2008
- Author(s)
  Kaneko H, Nishiguchi KM, Nakamura M, Kachi S, Terasaki H
- Journal Title
  
  Invest Ophthalmol Vis Sci 49(2)
  
  Pages: 781-787
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791263
[Journal Article] Identification of photoreceptor precursors in the pars plana during ocular development and after retinal injury.2008
- Author(s)
  Nishiguchi KM., et. al.
- Journal Title
  
  Invest Ophthalmol Vis Sci 49
  
  Pages: 422-428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592013
[Journal Article] Characteristics of bone marrow-derived microglia in the normal and injured retina2008
- Author(s)
  Kaneko H, Nishiguchi KM, Nakamura M, Kachi S, et.al.(他1名)
- Journal Title
  
  Invest Ophthalmol Vis Sci 49
  
  Pages: 4162-4168
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592013
[Journal Article] Identification of photoreceptor precursors in the pars plana during ocular development and after retinal injury2008
- Author(s)
  Nishiguchi KM, Kaneko H, Nakamura M, Kachi S, Terasaki H
- Journal Title
  
  Invest Ophthalmol Vis Sci 49(1)
  
  Pages: 422-428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791263
[Journal Article] Retardation of photoreceptor degeneration in detached retina of RD mouse2008
- Author(s)
  Kaneko H, Nishiguchi KM, Nakamura M, Kachi S, et.al.(他1名)
- Journal Title
  
  Invest Ophthalmol Vis Sci 49
  
  Pages: 781-787
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592013
[Journal Article] Characteristics of Bone Marrow-Derived Microglia in the Normal and Injured Retina2008
- Author(s)
  Kaneko H, Nishiguchi KM, Nakamura M, Kachi S, Terasaki H
- Journal Title
  
  Invest Ophthalmol Vis Sci 49(9)
  
  Pages: 4162-4168
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791263
[Journal Article] Identification of photoreceptor precursors in the pars plana during ocular development and after retinal injury.2008
- Author(s)
  Nishiguchi KM, Terasaki H, 他3名
- Journal Title
  
  Invest Ophthalmol Vis Sci 49(1)
  
  Pages: 422-428
- Data Source
  KAKENHI-PROJECT-20390448
[Journal Article] The role of VEGF and VEGFR2/Flkl in proliferation of retinal progenitor cells in murine retinal degeneration.2007
- Author(s)
  Nishiguchi KM., et. al.
- Journal Title
  
  Invest Ophthalmol Vis Sci 48
  
  Pages: 4315-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592013
[Journal Article] VEGF Stimulates Proliferation of Retinal Progenitor Cells via VEGFR2/Flk1 in Murine Retinal Degeneration2007
- Author(s)
  Nishiguchi KM
- Journal Title
  
  Invest Ophthalmol Vis Sci 48
  
  Pages: 4315-4320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791263
[Journal Article] The role of VEGF and VEGFR2/Flk1 in proliferation of retinal progenitor cells in murine retinal degeneration2007
- Author(s)
  Nishiguchi KM, Nakamura M, Kaneko H, Kachi S, et.al.(他1名)
- Journal Title
  
  Invest Ophthalmol Vis Sci 48
  
  Pages: 4315-4320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592013
[Journal Article] Identification of photoreceptor precursors in the pars plana during ocular development and after retinal injury2007
- Author(s)
  Nishiguchi KM
- Journal Title
  
  Invest Ophthalmol Vis Sci 49
  
  Pages: 422-428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791263
[Patent] 単一のAAVベクターによるゲノム編集を用いた遺伝子治療2022
- Inventor(s)
  西口康二、藤田幸輔
- Industrial Property Rights Holder
  国立大学法人東海国立大学機構
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Overseas
- Data Source
  KAKENHI-PROJECT-21K09673
[Presentation] 網膜色素変性に対する変異アレル特異的リフレームゲノム編集遺伝子治療の開発2023
- Author(s)
  藤田幸輔、山田和久、平澤輝一、西口康二
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K09673
[Presentation] Application of a Novel Genome Editing Approach for Treating a Common Mutation in a Large Gene Untreatable by Conventional Gene Supplementation2021
- Author(s)
  Koji M Nishiguchi
- Organizer
  Sonoma Eye Virtual Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09765
[Presentation] Development of Genome Editing Gene Therapy for Inherited Retinal Degeneration2021
- Author(s)
  Koji M Nishiguchi
- Organizer
  1st Asia Retina Congress
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09765
[Presentation] Retained plasticity at the visual cortex and recovery of vision in blind adult mice with retinal dystrophy following gene therapy2019
- Author(s)
  Koji M. Nishiguchi
- Organizer
  34th Asia-Pacific Academy of Ophthalmology Congress
- Invited
- Data Source
  KAKENHI-PROJECT-16K11315
[Presentation] Retained cortical plasticity and full recovery of rod-mediated visual acuity in blind adult mice with retinal dystrophy2018
- Author(s)
  Koji M. Nishiguchi
- Organizer
  6th Joint Meeting in Sendai
- Invited
- Data Source
  KAKENHI-PROJECT-16K11315
[Presentation] 全盲マウスに対する杆体視覚再建遺伝子治療時期によるレスキュー効果の差2017
- Author(s)
  西口康二
- Organizer
  第121回日本眼科学会総会
- Place of Presentation
  東京（東京国際フォーラム）
- Data Source
  KAKENHI-PROJECT-16K11315
[Presentation] Effect of timing of gene therapy to restore rod vision on the rescue effect in blind mice2017
- Author(s)
  Koji Nishiguchi
- Organizer
  第121回日本眼科学会
- Data Source
  KAKENHI-PROJECT-16K11315
[Presentation] The effect of timing on visual restoration of Gnat1/Pde6c double-knockout mouse through AAV-mediated gene supplementation2017
- Author(s)
  Koji Nishiguchi
- Organizer
  ARVO
- Data Source
  KAKENHI-PROJECT-16K11315
[Presentation] Regulation of pathologic retinal angiogenesis in mice and inhibition of VEGF-VEGFR2 binding by soluble heparan sulfate.2010
- Author(s)
  西口康二
- Organizer
  ARVO
- Place of Presentation
  Ft. Lauderdale, FL, USA
- Year and Date
  2010-05-02
- Data Source
  KAKENHI-PROJECT-21791676
[Presentation] グリコサミノグリカンによる病的網膜血管新生の抑制2010
- Author(s)
  西口康二
- Organizer
  第14回眼分子生物学研究会
- Place of Presentation
  大阪府池田市
- Year and Date
  2010-02-13
- Data Source
  KAKENHI-PROJECT-21791676
[Presentation] グリコサミノグリカンによる病的網膜血管新生の抑制2010
- Author(s)
  西口康二
- Organizer
  第14回眼分子生物学研究会
- Place of Presentation
  大阪
- Year and Date
  2010-02-13
- Data Source
  KAKENHI-PROJECT-21791676
[Presentation] Regulation of pathologic retinal angiogenesis in mice and inhibition of VEGF-VEGFR2 binding by soluble heparan sulfate.2010
- Author(s)
  Nishiguchi KM
- Organizer
  ARVO
- Place of Presentation
  Ft.Lauderdale, FL, USA
- Year and Date
  2010-05-02
- Data Source
  KAKENHI-PROJECT-21791676
[Presentation] Increased Number and Prolonged Presence of Retinal Precursors in the Pars Plana of rdl Mice2008
- Author(s)
  Nishiguchi KM
- Organizer
  ARVO 2008
- Place of Presentation
  Ft Lauderdale, FL, USA
- Year and Date
  2008-05-03
- Data Source
  KAKENHI-PROJECT-19791263
[Presentation] 加齢黄斑変性およびポリープ状脈絡膜血管症のHTRA1およびLOC387715遺伝子多型2008
- Author(s)
  中村誠、安間哲宏、菊池雅人、石川浩平、西原裕晶、山腰友珠、兼子裕規、西口康二、他
- Organizer
  第112回日本眼科学会総会
- Place of Presentation
  東京
- Year and Date
  2008-04-18
- Data Source
  KAKENHI-PROJECT-19592013
[Presentation] 毛様体扁平部と網膜の発生2008
- Author(s)
  西口康二
- Place of Presentation
  愛知県、蒲郡市
- Year and Date
  2008-08-24
- Data Source
  KAKENHI-PROJECT-19791263
[Presentation] Elevated C-reactive protein levels associated with the LOC387715/HTRA1 gene variants in Japanese patients with age-related macular degeneration2008
- Author(s)
  Nakamura M, Yasuma T, Kikuchi M, Ishikawa K, Nishihara H, Kaneko H, Nishiguchi KM, et.al.
- Organizer
  XIIIth International Symposium on Retinal Degeneration
- Place of Presentation
  Emeishan, Sichuan, China
- Data Source
  KAKENHI-PROJECT-19592013
[Presentation] Association of single nucleotide polymorphisms in the HTRA1, LOC387715, and CFH genes with neovascular age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV) in a Japanese population2008
- Author(s)
  Nakamura M, Yasuma T, Kikuchi M, Ishikawa K, Nishihara H, Yamakoshi T, Kaneko H, Nishiguchi KM, et.al
- Organizer
  The Association for Research in Vision and Ophthalmology (ARVO)
- Place of Presentation
  Fort Lauderdale, Florida, U.S.A
- Year and Date
  2008-04-29
- Data Source
  KAKENHI-PROJECT-19592013
[Presentation] Increased Number and Prolonged Presence of Retinal Precursors in the Pars Plana of rd1 Mice2008
- Author(s)
  Koji M Nishiguchi, Hiroki Kaneko, Makoto Nakamura, Shu Kachi, Hiroko Terasaki
- Organizer
  2008 ARVO
- Place of Presentation
  Ft Lauderdale, FL, USA
- Year and Date
  2008-05-01
- Data Source
  KAKENHI-PROJECT-19791263
[Presentation] Circulating bone marrow derived microglias engraft into the injured retina2008
- Author(s)
  Kaneko H, Nishiguchi KM, Nakamura M, Kachi S, et.al.
- Organizer
  Circulating bone marrow derived microglias engraft into the injured retina
- Place of Presentation
  Fort Lauderdale, Florida, U.S.A
- Year and Date
  2008-05-01
- Data Source
  KAKENHI-PROJECT-19592013
[Presentation] Circulating Bone Marrow Derived Microglias Engraft Into the Injured Retina2008
- Author(s)
  Hiroki Kaneko, Koji M Nishiguchi, Makoto Nakamura, Shu Kachi, Hiroko Terasaki
- Organizer
  ARVO 2008
- Place of Presentation
  Ft Lauderdale, FL, USA
- Year and Date
  2008-05-03
- Data Source
  KAKENHI-PROJECT-19791263
[Presentation] Prolonged presence of photoreceptor precursors in the ciliary epithelium of mice with hereditary retinal degeneration2008
- Author(s)
  Nishiguchi KM, Kaneko H, Nakamura M, Kachi S, et.al.
- Organizer
  The Association for Research in Vision and Ophthalmology (ARVO)
- Place of Presentation
  Fort Lauderdale, Florida, U.S.A
- Year and Date
  2008-04-29
- Data Source
  KAKENHI-PROJECT-19592013
[Presentation] 毛様体扁平部と網膜の発生2008
- Author(s)
  Nishiguchi KM
- Organizer
  Japan Macular Club
- Place of Presentation
  愛知県蒲郡市
- Year and Date
  2008-08-24
- Data Source
  KAKENHI-PROJECT-19791263
[Presentation] Murine retinal progenitor cells in the ciliary body epithelium may participate in neurogenesis of the peripheral retina in vivo2007
- Author(s)
  Nishiguchi KM, Kaneko H, Nakamura M, Kachi S, et.al
- Organizer
  The Association for Research in Vision and Ophthalmology (ARVO)
- Place of Presentation
  Fort Lauderdale, Florida, U.S.A
- Year and Date
  2007-05-09
- Data Source
  KAKENHI-PROJECT-19592013
[Presentation] 毛様体上皮細胞の網膜神経細胞への分科と周辺網膜の形成2007
- Author(s)
  西口康二
- Organizer
  第46回日本網膜硝子体学会
- Place of Presentation
  青森県、青森市
- Year and Date
  2007-11-23
- Data Source
  KAKENHI-PROJECT-19791263
[Presentation] 骨髄由来細胞のマウス網膜内への生着2007
- Author(s)
  兼子裕規、西口康二、中村誠、加地秀、寺崎浩子
- Organizer
  第46回日本網膜硝子体学会
- Place of Presentation
  青森県、青森市
- Year and Date
  2007-11-24
- Data Source
  KAKENHI-PROJECT-19791263
[Presentation] KCNV2遺伝子に変異が検出されたCone dystrophy with supernormal rod ERGの一例2007
- Author(s)
  中村誠、安間哲宏、西口康二、伊藤逸毅、近藤峰生、寺崎浩子
- Organizer
  第61回日本臨床眼科学会
- Place of Presentation
  京都府、京都市
- Year and Date
  2007-10-13
- Data Source
  KAKENHI-PROJECT-19791263
[Presentation] 骨髄由来細胞のマウス網膜内への生着2007
- Author(s)
  兼子裕規、西口康二、中村誠、加地秀、他
- Organizer
  第46回日本網膜硝子体学会
- Place of Presentation
  弘前
- Year and Date
  2007-11-24
- Data Source
  KAKENHI-PROJECT-19592013
[Presentation] 毛様体上皮細胞の網膜神経細胞への分科と周辺網膜の形成2007
- Author(s)
  西口康二
- Organizer
  第46回日本網膜硝子体学会
- Place of Presentation
  青森
- Year and Date
  2007-11-23
- Data Source
  KAKENHI-PROJECT-19791263
[Presentation] KCNV2遺伝子に変異が検出されたcone dystrophy with supernormal rod ERGの一例2007
- Author(s)
  中村誠、安間哲宏、西口康二、他
- Organizer
  第61回日本臨床眼科学会
- Place of Presentation
  京都
- Year and Date
  2007-10-13
- Data Source
  KAKENHI-PROJECT-19592013

1. Fujita Kosuke (80708115)

# of Collaborated Projects: 7 results

# of Collaborated Products: 3 results
2. Nakazawa Toru (30361075)

# of Collaborated Projects: 5 results

# of Collaborated Products: 5 results
3. KACHI Shu (30345904)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
4. Ikeda Yasuhiro (20380389)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 下澤律浩 (50300786)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. NAKAMURA Makoto (60283438)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
7. ISAO Date (70236785)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TERASAKI Hiroko (40207478)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. KONDO Mineo (80303642)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. ITO Yasuki (10313991)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 丸山和一 (10433244)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 河合純 (30391923)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 國方彦志 (40361092)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 田中佑治 (40625513)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 佐藤孝太 (50732327)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 横山悠 (00597312)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 村山奈美枝 (60597516)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 秋山雅人 (10757686)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 小柳俊人 (80880690)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 長縄慎二 (50242863)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 曽根三千彦 (30273238)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 田岡俊昭 (30305734)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
23. 伊藤倫太郎 (80813336)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
24. ITO Masayoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. KAWAJI Hideya

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. UENO Shinji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. Bito Haruhiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 宮田聖子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 奥野浩行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nishiguchi Koji 西口 康二

KOJI Nishiguchi 西口 康二

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革新的なゲノム編集遺伝子治療実現のための包括的基盤形成Principal Investigator

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Development of expression analysis for retinitis pigmentosa causative genes using peripheral blood by epigenome editingPrincipal Investigator

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Comparison of plasticity between rod and cone visual pathwaysPrincipal Investigator

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Search for genetic causes and autoantibodies of retinitis pigmentosa sine pigmentoPrincipal Investigator

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眼内炎症における補体系と眼内液中硫酸化グリコサミノグリカンの役割の検討Principal Investigator

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Regulatory mechanisms of neuronal regeneration in the retina and role of the pars plana.Principal Investigator

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Nishiguchi Koji 西口康二

KOJI Nishiguchi 西口康二