nagahashi masayuki 永橋昌幸

… Alternative Names

NAGAHASHI Masayuki 永橋昌幸

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Researcher Number	30743918
Other IDs
Affiliation (Current)	2025: 兵庫医科大学, 医学部, 准教授 2025: 新潟大学, 医歯学総合研究科, 客員研究員
Affiliation (based on the past Project Information) *help	2021 – 2025: 兵庫医科大学, 医学部, 准教授 2021 – 2023: 新潟大学, 医歯学総合研究科, 客員研究員 2018 – 2022: 新潟大学, 医歯学総合病院, 研究准教授 2015 – 2017: 新潟大学, 医歯学総合病院, 講師 2014: 新潟大学, 医歯学系, 助教
Review Section/Research Field	Principal Investigator Basic Section 55010:General surgery and pediatric surgery-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / General surgery Except Principal Investigator Basic Section 55020:Digestive surgery-related / Digestive surgery / Basic Section 55010:General surgery and pediatric surgery-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / General surgery / Medium-sized Section 62:Applied informatics and related fields / Basic Section 56010:Neurosurgery-related / Gastroenterology
Keywords	Principal Investigator 乳癌 / スフィンゴシン-1-リン酸 / 脂質メディエーター / 治療 / スフィンゴシン－1－リン酸 / 薬剤耐性 / 癌代謝 / スフィンゴシンキナーゼ / 創薬 / マウスモデル … More / ドラッグデリバリー / ドラッグデリバリーシステム / トリプルネガティブ / TP53 / スフィンゴシン‐1-リン酸 / 腫瘍免疫微小環境 / トリプルネガティブ乳癌 / スフィンゴシンキナーゼ1型 / リンパ管新生 / 血管新生 / 癌 / リンパ液 / 癌間質液 / リンパ節転移 / 癌と宿主 / スフィンゴシン-１-リン酸 / CRISPR/Cas9 / メタボローム … More Except Principal Investigator 脂質メディエーター / スフィンゴシン-1-リン酸 / 乳癌 / 免疫組織化学 / 胃癌 / 免疫組織化学染色 / 大腸癌 / 化学療法 / 癌遺伝子パネル / S1P / セラミド / 膵癌 / CRISPR/Cas9 / スフィンゴシンキナーゼ1型 / 変異シグネチャー / 消化器癌 / 細菌叢 / バイオマーカー / 薬物療法 / マイクロサテライト不安定性 / FISH / HER2 / 抗HER2療法 / 遺伝子パネル検査 / 精密医療 / mutational signature / がん遺伝子パネル検査 / TCGA / SphK1 / 癌微小環境 / 発癌 / 潰瘍性大腸炎 / pSphK1 / 食道癌 / 胆道癌 / スフィンゴシンキナーゼ１型 / リピドミクス解析 / リンパ管新生 / リンパ節転移 / DNA二重鎖切断 / サブタイプ / 腫瘍免疫微小環境 / 腫瘍浸潤リンパ球 / 癌移植マウスモデル / 患者由来癌異種移植片 / 薬剤感受性 / 患者由来癌オルガノイド / 治療効果予測 / 治療開発 / サイトカイン / エリブリン / 乳がん / 免疫チェックポイント阻害薬 / 相同組換え修復欠損 / トリプルネガティブ / パスウェイ解析 / 遺伝子異常 / 胆囊癌 / Heterogeneity / 胆嚢癌 / 生存解析 / 外科切除 / HER2陽性胆嚢癌 / 塩基置換 / 固形癌 / バイオインフォマティクス / ターゲット遺伝子パネル検査 / 高次元データ解析システム / ゲノム / 高次元データ解析 / 腫瘍変異負荷 / ゲノム高次元データ解析 / 人工知能 / 深層学習 / 膵島移植 / 糖尿病 / 移植免疫 / 臓器移植 / 細胞移植 / 免疫微小環境 / 腸内細菌叢 / 炎症 / 回腸嚢炎 / 体液 / 伝播経路 / 消化器 / 癌遺伝子異常 / ヒト共生細菌叢 / NOTCH / NOTCHシグナル / 術前化学療法 / DNAミスマッチ修復機構 / tumor mutation burden / nivolumab / PD-L1 / ミスマッチ修復タンパク質 / HER2陽性胃癌 / ERBB2 / trastuzumab / 癌遺伝子解析パネル / HER2陽性 / データベース / がんゲノム / 腫瘍細胞培養 / ドライバー遺伝子 / 遺伝子パネル / プレシジョンメディシン / 独自培養細胞株 / 悪性髄膜腫 / homologous recombination / 白金系抗癌剤 / 相同組換え修復 / 抗がん剤耐性 / 脈管侵襲 / スフィンゴ脂質 / 肝細胞癌 / 発癌メカニズム / 腫瘍内リンパ球浸潤 / 低分化胞巣 / TMB-H / SMAD4 / SMAD2 / ACVR2A / TGFBR2 / TGF-β / スフィンゴシン‐１‐リン酸 / 炎症性発癌 / 遺伝子解析 / スフィンゴシン1リン酸 / 炎症性腸疾患 / アクチビン受容体 / 次世代シークエンサー / Hypermutation / アクチビン2型受容体 / MKN74 ヒト胃癌細胞 / CRISPR-Cas9 / アクチビン受容体2A型 / マイクロサテライト不安定 / スフィンゴシン-１-リン酸 / スフィンゴシンー１ーリン酸 / 抗エストロゲン剤耐性株 / スフィンゴシン‐1-リン酸 / ホルモン療法 / スフィンゴシン－1－リン酸 / リンパ行性転移 / リンパ行性進展転移 / 細胞情報伝達機構 / 胆道疾患 / 胆汁酸 / 食道外科学 / リンパ管侵襲 / 食道扁平上皮癌 / リンパ行性進展 / 肝臓学 / 消化器内科 / シスプラチン / 薬剤耐性 / エクソソーム / 肝がん / 転移能 / 細胞増殖能 / B/6系マウス / リンパ管浸潤 / 細胞外基質 / ダブルノックアウトマウス / 膵臓外科学 / 胆道外科学 / CAM5.2モノクローナル抗体 / HE染色 / 大腸粘膜下層浸潤癌 / 内視鏡的粘膜切除術 / 免疫染色 / 粘膜下層浸潤癌 / 簇出 / p62 / Keap1 / Nrf2 / KRAS / NQO1 / 抗癌剤耐性 / スフィンゴシンキナーゼ / RBP / RTP / 末梢静脈栄養 / Rapid turnover protein / インスリン抵抗性 / タンパク代謝 / 低脂肪経腸栄養剤 / 乳び胸 / 経腸栄養 / CRP / 術後回復 / 脂肪乳剤 / 静脈栄養 / カルニチン / γ-H2AX / 上皮内癌 / DNA損傷修復機構 / field carcinogenesis / p53-binding protein 1 / 表層拡大進展 / 胆管癌 / 早期DNA損傷修復機構 Less

脂質メディエーター分子機構の癌特異的阻害による乳癌新治療の実現へ向けた前臨床研究Principal Investigator
- Principal Investigator
  
  永橋昌幸
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Hyogo Medical University
乳癌患者由来オルガノイド・動物モデルの臨床的有用性の検証と新規治療開発への応用
- Principal Investigator
  
  樋口智子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Hyogo Medical University
乳癌における腫瘍浸潤リンパ球の分子病理学的解析と腫瘍免疫微小環境予測モデルの構築
- Principal Investigator
  
  金岡遥
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Hyogo Medical University
トリプルネガティブ乳癌における変異シグネチャー解析の臨床病理学的意義の解明
- Principal Investigator
  
  土田純子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Niigata University
Development of biomarkers and new treatments for metastatic breast cancer by eribulin
- Principal Investigator
  
  三好康雄
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Hyogo Medical University
乳癌における脂質メディエーターを標的とする薬物送達システムを用いた新規治療の開発Principal Investigator
- Principal Investigator
  
  永橋昌幸
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Hyogo Medical University
Development of Artificial Intelligence by Deep Learning Based on Genomic High-Dimensional Data Analysis System for Gastrointestinal Cancer
- Principal Investigator
  
  WAKAI TOSHIFUMI
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Niigata University
Establishment of classification for base substitution pattern and assessment for clinical implication of mutational signature in solid tumors
- Principal Investigator
  
  Hirose Yuki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Niigata University
Comprehensive cancer-related pathway analysis of genetic abnormalities in HER2-positive gallbladder cancer and their clinical significance
- Principal Investigator
  
  Sakata Jun
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Niigata University
トリプルネガティブ乳癌におけるTP53と脂質分子の相補的な細胞制御機構の解明Principal Investigator
- Principal Investigator
  
  永橋昌幸
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Hyogo Medical University
Pathogenesis of pouchitis after ileal pouch anal anastomosis for ulcerative colitis: Analysis of intestinal microbiota and lipid mediators.
- Principal Investigator
  
  Kameyama Hitoshi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Niigata University
Clinical Significance of Lipid Mediator in the tumor Microenvironment of Pancreatic Adenocarcinoma
- Principal Investigator
  
  TAKIZAWA KAZUYASU
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Niigata University
Extend islet graft survival in pancreatic islet transplantation by applying the immunoregulatory mechanism of ceramide
- Principal Investigator
  
  Kobayashi Takashi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Niigata University
Clinical significance of comprehensive genomic analysis in HER2 positive gastric cancer
- Principal Investigator
  
  Usui Kenji
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Niigata University
Verification of microsatellite instability status evaluated by cancer gene panel testing and clinical significance in the drug treatment for gastric cancer
- Principal Investigator
  
  Hanyu Takaaki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Niigata University
Clinical significance of NOTCH signaling for the response of preoperative chemotherapy in esophageal cancer
- Principal Investigator
  
  Ichikawa Hiroshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Niigata University
Elucidation of the interaction between human commensal bacterial flora and host genetic alterations in the digestive tract
- Principal Investigator
  
  Wakai Toshifumi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Niigata University
The role of lipid mediator in the tumor immune microenvironment of breast cancer and its therapeutic applicationPrincipal Investigator
- Principal Investigator
  
  Nagahashi Masayuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Hyogo Medical University
  Niigata University
The new classification of colorectal cancer focusing on differences of molecular mechanisms in TGF-b signal pathway
- Principal Investigator
  
  Shimada Yoshifumi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Niigata University
The role of lipid mediators for lymphvascular invasion in hepatocellular carcinoma and its clinical significance
- Principal Investigator
  
  Hirose Yuki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Niigata University
Clinical significance of defective DNA double-strand break repair pathway in gastric cancer
- Principal Investigator
  
  Katada Tomohiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Niigata University
Identification of targeted gene mutations for precision based medicine in malignant meningioma
- Principal Investigator
  
  HIRAISHI TETSUYA
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Niigata University
Mechanisms of cancer metabolism and drug resistance regulated by S1P in triple negative breast cancerPrincipal Investigator
- Principal Investigator
  
  Nagahashi Masayuki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Niigata University
High-dimensional data analysis platform realizing cancer genome medicine
- Principal Investigator
  
  Okuda Shujiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 62:Applied informatics and related fields
- Research Institution
  Niigata University
Elucidation of molecular mechanisms of a lipid mediator in resistance of breast cancer hormone therapy and its clinical significance
- Principal Investigator
  
  Ikarashi Mayuko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Niigata University
The role and clinical relevance of Activin receptor type 2A mutation in gastric cancer
- Principal Investigator
  
  Yuza Kizuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
Role of lipid mediator in colitis-associated cancer
- Principal Investigator
  
  Kameyama Hitoshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
Roles and clinical significance of lipid mediator producing enzymes in the formation of the tumor microenvironment of pancreatic cancer
- Principal Investigator
  
  Nakajima Masato
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
The mechanism of exosome-mediated drug resistance in hepatoma cells
- Principal Investigator
  
  Yasunobu MATSUDA
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Niigata University
Clinical significance of sphingosine-1-phosphate and sphingosine kinase 1 in lymphatic spread of esophageal cancer
- Principal Investigator
  
  Ichikawa Hiroshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
Elucidation of a novel cell signaling mechanism by lipid mediators and bile acids in biliary diseases
- Principal Investigator
  
  WAKAI TOSHIFUMI
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
Serum carnitine kinetics by administration of fat emulsion at the perioperative period and effect of intravenous administration of L-carnitine
- Principal Investigator
  
  Koyama Yu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Niigata University
Clinical Significance and elucidation of molecular regulation mechanism of lipid mediators in invasion and metastatic ability of gastric cancer
- Principal Investigator
  
  Hanyu Takaaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
The molecular mechanism of a lipid mediator involved in metabolic dynamics of breast cancerPrincipal Investigator
- Principal Investigator
  
  Nagahashi Masayuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Niigata University
Elucidation of molecular mechanism of lipid mediator involved in metastatic ability of biliary tract cancer / pancreatic cancer and clinical application
- Principal Investigator
  
  WAKAI TOSHIFUMI
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
The role of a lipid mediator in an interaction between cancer and the host, promoting breast cancer progressionPrincipal Investigator
- Principal Investigator
  
  Nagahashi Masayuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  General surgery
- Research Institution
  Niigata University
Elucidation of the mechanism of drug resistance in colorectal cancer by p62-Keap 1-Nrf2 pathway
- Principal Investigator
  
  KAMEYAMA Hitoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
Biological evaluation and significance of tumor budding using fluorescence immunohistochemistry in pT1b colorectal cancer
- Principal Investigator
  
  NOGAMI Hitoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University
Early DNA damage response in residual carcinoma in situ at ductal stumps and local recurrence in patients undergoing resection for extrahepatic cholangiocarcinoma
- Principal Investigator
  
  WAKAI Toshifumi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Niigata University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 Other

All Journal Article Presentation Patent

[Journal Article] Targeting Sphingosine-1-Phosphate Signaling in Breast Cancer2024
- Author(s)
  Nagahashi Masayuki、Miyoshi Yasuo
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 25 Issue: 6 Pages: 3354-3354
- DOI
  10.3390/ijms25063354
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19522
[Journal Article] Baseline interleukin-6 is a prognostic factor for patients with metastatic breast cancer treated with eribulin2023
- Author(s)
  Bun Ayako、Nagahashi Masayuki、Kuroiwa Mamiko、Komatsu Miki、Miyoshi Yasuo
- Journal Title
  
  Breast Cancer Research and Treatment
  
  Volume: 202 Issue: 3 Pages: 575-583
- DOI
  10.1007/s10549-023-07086-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08764
[Journal Article] Clinical Significance of Phosphorylated Sphingosine Kinase 1 Expression in Pancreatic Ductal Adenocarcinoma2023
- Author(s)
  Nagaro H, Ichikawa H, Takizawa K, Nagahashi M, Abe S, Hirose Y, Moro K, Miura K, Nakano M, Shimada Y, Sakata J, Wakai T
- Journal Title
  
  Anticancer Res
  
  Volume: 43 Issue: 9 Pages: 3969-3977
- DOI
  10.21873/anticanres.16584
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02998
[Journal Article] Copy number alteration is an independent prognostic biomarker in triple-negative breast cancer patients2023
- Author(s)
  Nagahashi M, Ling Y, Toshikawa C, Hayashida T, Kitagawa Y, Futamura M, Kuwayama T, Nakamura S, Yamauchi H, Yamauchi T, Kaneko K, Kanbayashi C, Sato N, Tsuchida J, Moro K, Nakajima M, Shimada Y, Ichikawa H, Lyle S, Miyoshi Y, Takabe K, Okuda S, Wakai T.
- Journal Title
  
  Breast Cancer
  
  Volume: - Issue: 4 Pages: 584-595
- DOI
  10.1007/s12282-023-01449-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19522, KAKENHI-PROJECT-21K17850
[Journal Article] スフィンゴシン-1-リン酸のがん進展における生体内での作用メカニズムと臨床的意義2022
- Author(s)
  永橋　昌幸
- Journal Title
  
  兵庫医科大学医学会雑誌
  
  Volume: 46 Pages: 57-63
- Data Source
  KAKENHI-PROJECT-21K19522
[Journal Article] 潰瘍性大腸炎術後回腸嚢炎とスフィンゴシン-1-リン酸の関連2022
- Author(s)
  亀山仁史、永橋昌幸、田島陽介、小柳英人、廣瀬雄己、中野麻恵、中野雅人、島田能史、竹内志穂、奥田修二郎、若井俊文
- Journal Title
  
  新潟医学会雑誌
  
  Volume: 136 Pages: 219-224
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09074
[Journal Article] Histopathological characteristics and artificial intelligence for predicting tumor mutational burden-high colorectal cancer2021
- Author(s)
  Shimada Yoshifumi、Okuda Shujiro、Watanabe Yu、Tajima Yosuke、Nagahashi Masayuki、Ichikawa Hiroshi、Nakano Masato、Sakata Jun、Takii Yasumasa、Kawasaki Takashi、Homma Kei-ichi、Kamori Tomohiro、Oki Eiji、Ling Yiwei、Takeuchi Shiho、Wakai Toshifumi
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: - Issue: 6 Pages: 547-559
- DOI
  10.1007/s00535-021-01789-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04123, KAKENHI-PROJECT-18K08612, KAKENHI-PROJECT-21H02998, KAKENHI-PROJECT-21K17850
[Journal Article] Clinical Utility of ypTNM Stage Grouping in the 8th Edition of the American Joint Committee on Cancer TNM Staging System for Esophageal Squamous Cell Carcinoma2021
- Author(s)
  Natsuru Sudo, Hiroshi Ichikawa, Yusuke Muneoka, Takaaki Hanyu, Yosuke Kano, Takashi Ishikawa, Yuki Hirose, Kohei Miura, Yoshifumi Shimada, Masayuki Nagahashi, Jun Sakata, Takashi Kobayashi, Takeo Bamba, Satoru Nakagawa, Shin-Ichi Kosugi, Toshifumi Wakai
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: 28 Issue: 2 Pages: 650-660
- DOI
  10.1245/s10434-020-09181-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09212
[Journal Article] Profiling of host genetic alterations and intra-tumor microbiomes in colorectal cancer.2021
- Author(s)
  Okuda S, Shimada Y, Tajima Y, Yuza K, Hirose Y, Ichikawa H, Nagahashi M, Sakata J, Ling Y, Miura N, Sugai M, Watanabe Y, Takeuchi S, Wakai T
- Journal Title
  
  Comput Struct Biotechnol J
  
  Volume: 19 Pages: 3330-3338
- DOI
  10.1016/j.csbj.2021.05.049
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22651, KAKENHI-PROJECT-21K17850
[Journal Article] Dysregulation of sphingolipid metabolic enzymes leads to high levels of sphingosine‐1‐phosphate and ceramide in human hepatocellular carcinoma2021
- Author(s)
  Miura Kohei、Nagahashi Masayuki、Prasoon Pankaj、Hirose Yuki、Kobayashi Takashi、Sakata Jun、Abe Manabu、Sakimura Kenji、Matsuda Yasunobu、Butash Ali L.、Katsuta Eriko、Takabe Kazuaki、Wakai Toshifumi
- Journal Title
  
  Hepatology Research
  
  Volume: 51 Issue: 5 Pages: 614-626
- DOI
  10.1111/hepr.13625
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-18K08672
[Journal Article] Plasma Sphingosine-1-Phosphate Levels Are Associated with Progression of Estrogen Receptor-Positive Breast Cancer2021
- Author(s)
  Ikarashi Mayuko、Tsuchida Junko、Nagahashi Masayuki、Takeuchi Shiho、Moro Kazuki、Toshikawa Chie、Abe Shun、Ichikawa Hiroshi、Shimada Yoshifumi、Sakata Jun、Koyama Yu、Sato Nobuaki、Hait Nitai C.、Ling Yiwei、Okuda Shujiro、Takabe Kazuaki、Wakai Toshifumi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 24 Pages: 13367-13367
- DOI
  10.3390/ijms222413367
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03714, KAKENHI-PROJECT-21K17850
[Journal Article] NQO1 as a Marker of Chemosensitivity and Prognosis for Colorectal Liver Metastasis2021
- Author(s)
  Hirose Y, Sakata J, Kobayashi T, Miura K, Yuza K, Nakano M, Ichikawa H, Nagahashi M, Shimada Y, Kameyama H, Wakai T
- Journal Title
  
  Anticancer Res
  
  Volume: 41 Issue: 3 Pages: 1563-1570
- DOI
  10.21873/anticanres.14916
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02998
[Journal Article] Low intratumoral genetic neutrophil-to-lymphocyte ratio (NLR) is associated with favorable tumor immune microenvironment and with survival in triple negative breast cancer (TNBC)2021
- Author(s)
  Tokumaru Y, Oshi M, Patel A, Katsuta E, Yan L, Angarita FA, Dasgupta S, Nagahashi M, Matsuhashi N, Futamura M, Yoshida K, Takabe K.
- Journal Title
  
  Am J Cancer Res
  
  Volume: 11 Pages: 3320-3334
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03714
[Journal Article] ASO Author Reflections: ypTNM Stage Grouping in the 8th Edition of the AJCC Cancer Staging Manual Refines the Prognostic Prediction for Patients with Esophageal Squamous Cell Carcinoma Undergoing Neoadjuvant Chemotherapy2021
- Author(s)
  Natsuru Sudo, Hiroshi Ichikawa, Yusuke Muneoka, Takaaki Hanyu, Yosuke Kano, Takashi Ishikawa, Yuki Hirose, Kohei Miura, Yoshifumi Shimada, Masayuki Nagahashi, Jun Sakata, Takashi Kobayashi, Takeo Bamba, Satoru Nakagawa, Shin-Ichi Kosugi, Toshifumi Wakai
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: 28 Issue: 2 Pages: 661-662
- DOI
  10.1245/s10434-020-09184-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09212
[Journal Article] Intra-tumoral angiogenesis is associated with inflammation, immune reaction and metastatic recurrence in breast cancer2020
- Author(s)
  Oshi M, Newman S, Tokumaru Y, Yan L, Matsuyama R, Endo I, Nagahashi M, Takabe K
- Journal Title
  
  Int J Mol Sci
  
  Volume: 21 Issue: 18 Pages: 6708-6708
- DOI
  10.3390/ijms21186708
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03714
[Journal Article] Inguinal Herniation After Living Donor Kidney Transplantation: A Case Report.2020
- Author(s)
  Kobayashi T, Miura K, Saito K, Tasaki M, Saito K, Sakata J, Takizawa K, Katada T, Hirose Y, Yuza K, Ando T, Nagahashi M, Kameyama H, Wakai T.
- Journal Title
  
  Transplant Proc
  
  Volume: 52 Issue: 6 Pages: 1940-1943
- DOI
  10.1016/j.transproceed.2020.02.131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21628
[Journal Article] Intratumoral Adipocyte-High Breast Cancer Enrich for Metastatic and Inflammation-Related Pathways but Associated with Less Cancer Cell Proliferation2020
- Author(s)
  Tokumaru Y, Oshi M, Katsuta E, Yan L, Huang JL, Nagahashi M, Matsuhashi N, Futamura M, Yoshida K, Takabe K
- Journal Title
  
  Int J Mol Sci
  
  Volume: 21 Issue: 16 Pages: 5744-5744
- DOI
  10.3390/ijms21165744
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19576
[Journal Article] Sphingosine Kinase 1 is Associated With Immune Cell Related Gene Expressions in Human Breast Cancer2020
- Author(s)
  Junko Tsuchida, Masayuki Nagahashi, Masato Nakajima, Eriko Katsuta, Omar M. Rashid, Qianya Qi, Li Yan, Shujiro Okuda, Kazuaki Takabe, Toshifumi Wakai
- Journal Title
  
  Journal of Surgical Research
  
  Volume: 15 Pages: 645-656
- DOI
  10.1016/j.jss.2020.06.057
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K18049, KAKENHI-PROJECT-19H03714
[Journal Article] Genetic profiling for diffuse type and genomically stable subtypes in gastric cancer2020
- Author(s)
  Ling Yiwei、Watanabe Yu、Nagahashi Masayuki、Shimada Yoshifumi、Ichikawa Hiroshi、Wakai Toshifumi、Okuda Shujiro
- Journal Title
  
  Computational and Structural Biotechnology Journal
  
  Volume: 18 Pages: 3301-3308
- DOI
  10.1016/j.csbj.2020.10.021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04123, KAKENHI-PROJECT-19K20397
[Journal Article] RNF43 mutation is associated with aggressive tumor biology along with BRAF V600E mutation in right-sided colorectal cancer2020
- Author(s)
  Matsumoto A, Shimada Y, Nakano M, Oyanagi H, Tajima Y, Nakano M, Kameyama H, Hirose Y, Ichikawa H, Nagahashi M, Nogami H, Maruyama S, Takii Y, Ling Y, Okuda S, Wakai T.
- Journal Title
  
  Oncology Reports
  
  Volume: 43 Pages: 1853-1862
- DOI
  10.3892/or.2020.7561
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08612, KAKENHI-PROJECT-17K10624, KAKENHI-PROJECT-19K20397
[Journal Article] Living donor liver transplantation for more than 30-year survived patients with native liver after Kasai operation for biliary atresia2020
- Author(s)
  Kobayashi T, Miura K, Kubota M, Kinoshita Y, Sakata J, Takizawa K, Katada T, Hirose Y, Yuza K, Ando T, Miura Y, Nagahashi M, Kameyama H, Wakai T
- Journal Title
  
  Transplantation Reports
  
  Volume: 5 Pages: 100052-100052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21628
[Journal Article] Hyperbilirubinemia predicts the infectious complications after esophagectomy for esophageal cancer2019
- Author(s)
  Muneoka Yusuke、Ichikawa Hiroshi、Kosugi Shin-ichi、Hanyu Takaaki、Ishikawa Takashi、Kano Yosuke、Shimada Yoshifumi、Nagahashi Masayuki、Sakata Jun、Kobayashi Takashi、Kameyama Hitoshi、Akazawa Kohei、Wakai Toshifumi
- Journal Title
  
  Annals of Medicine and Surgery
  
  Volume: 39 Pages: 16-21
- DOI
  10.1016/j.amsu.2019.02.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04093, KAKENHI-PROJECT-16K10491
[Journal Article] A dramatic, transient effect of nivolumab combined with whole-brain irradiation for the treatment of primary meningeal melanomatosis2019
- Author(s)
  Tomoyoshi Ota1, Manabu Natsumeda1*, Shisei Yoshida2, Yoshihiro Tsukamoto2, Jun Watanabe1, Yu Kanemaru1,3, Kazuhiro Ando1, Yuuichi Yoshida1, Tetsuya Hiraishi1, Kouichirou Okamoto4, Masayuki Nagahashi5, Toshifumi Wakai5, Akiyoshi Kakita3, Makoto Oishi1 and Yukihiko Fujii1
- Journal Title
  
  Clinical Case Reports and Reviews
  
  Volume: 5 Pages: 1-4
- Data Source
  KAKENHI-PROJECT-18K08990
[Journal Article] Phospho-Sphingosine Kinase 1 Expression in Lymphatic Spread of Esophageal Squamous Cell Carcinoma2019
- Author(s)
  Nemoto Mariko、Ichikawa Hiroshi、Nagahashi Masayuki、Hanyu Takaaki、Ishikawa Takashi、Kano Yosuke、Muneoka Yusuke、Wakai Toshifumi
- Journal Title
  
  Journal of Surgical Research
  
  Volume: 234 Pages: 123-131
- DOI
  10.1016/j.jss.2018.09.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10491
[Journal Article] Clinical application of ceramide in cancer treatment2019
- Author(s)
  Kazuki Moro, Masayuki Nagahashi, Emmanuel Gabriel, Kazuaki Takabe & Toshifumi Wakai
- Journal Title
  
  Breast Cancer
  
  Volume: 26 Issue: 4 Pages: 407-415
- DOI
  10.1007/s12282-019-00953-8
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19576
[Journal Article] SMAD4 alteration associates with invasive-front pathological markers and poor prognosis in colorectal cancer2019
- Author(s)
  Oyanagi H, Shimada Y, Nagahashi M, Ichikawa H, Tajima Y, Abe K, Nakano M, Kameyama H, Takii Y, Kawasaki T, Homma KI, Ling Y, Okuda S, Takabe K, Wakai T.
- Journal Title
  
  Histopathology
  
  Volume: 74 Issue: 6 Pages: 873-882
- DOI
  10.1111/his.13805
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08612
[Journal Article] Targeting the SphK1/S1P/S1PR1 Axis That Links Obesity, Chronic Inflammation, and Breast Cancer Metastasis2018
- Author(s)
  Nagahashi Masayuki、Yamada Akimitsu、Katsuta Eriko、Aoyagi Tomoyoshi、Huang Wei-Ching、Terracina Krista P.、Hait Nitai C.、Allegood Jeremy C.、Tsuchida Junko、Yuza Kizuki、Nakajima Masato、Abe Manabu、Sakimura Kenji、Milstien Sheldon、Wakai Toshifumi、Spiegel Sarah、Takabe Kazuaki
- Journal Title
  
  Cancer Research
  
  Volume: 78 Issue: 7 Pages: 1713-1725
- DOI
  10.1158/0008-5472.can-17-1423
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05676, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-25000015, KAKENHI-PROJECT-17K01972, KAKENHI-PROJECT-16H04650, KAKENHI-PROJECT-17K19444, KAKENHI-PROJECT-16K19055, KAKENHI-PROJECT-16K19888
[Journal Article] Expression of phosphorylated sphingosine kinase 1 is associated with diffuse type and lymphatic invasion in human gastric cancer.2018
- Author(s)
  Hanyu T, Nagahashi M, Ichikawa H, Ishikawa T, Kobayashi T, Wakai T.
- Journal Title
  
  Surgery
  
  Volume: [Epub ahead of print] Issue: 6 Pages: 1301-1306
- DOI
  10.1016/j.surg.2017.11.024
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10087
[Journal Article] Generation of sphingosine-1-phosphate is enhanced in biliary tract cancer patients and is associated with lymphatic metastasis2018
- Author(s)
  Hirose Y, Nagahashi M, Katsuta E, Yuza K, Miura K, Sakata J, Kobayashi T, Ichikawa H, Shimada Y, Kameyama H, McDonald KA, Takabe K, Wakai T
- Journal Title
  
  Sci Rep
  
  Volume: 8 Issue: 1 Pages: 10814-10814
- DOI
  10.1038/s41598-018-29144-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15610
[Journal Article] Different Roles of Sphingosine Kinase 1 and 2 in Pancreatic Cancer Progression2018
- Author(s)
  Yuza Kizuki、Nakajima Masato、Nagahashi Masayuki、Tsuchida Junko、Hirose Yuki、Miura Kohei、Tajima Yosuke、Abe Manabu、Sakimura Kenji、Takabe Kazuaki、Wakai Toshifumi
- Journal Title
  
  Journal of Surgical Research
  
  Volume: 232 Pages: 186-194
- DOI
  10.1016/j.jss.2018.06.019
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01972, KAKENHI-PROJECT-17K10692
[Journal Article] Upregulation of phosphorylated sphingosine kinase 1 expression in colitis-associated cancer.2018
- Author(s)
  Yuza K, Nagahashi M, Shimada Y, Nakano M, Tajima Y, Kameyama H, Nakajima M, Takabe K, Wakai T.
- Journal Title
  
  Journal of surgical research
  
  Volume: 231 Pages: 323-330
- DOI
  10.1016/j.jss.2018.05.085
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10624
[Journal Article] Genomic characterization of colitis-associated colorectal cancer.2018
- Author(s)
  Kameyama H, Nagahashi M, Shimada Y, Tajima Y, Ichikawa H, Nakano M, Sakata J, Kobayashi T, Narayanan S, Takabe K, Wakai T.
- Journal Title
  
  World journal of surgical oncology
  
  Volume: 16 Issue: 1 Pages: 121-121
- DOI
  10.1186/s12957-018-1428-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10624
[Journal Article] Next generation sequencing-based gene panel tests for the management of solid tumors.2018
- Author(s)
  Nagahashi M, Shimada Y, Ichikawa H, Kameyama H, Takabe K, Okuda S, Wakai T.
- Journal Title
  
  Cancer Sci.
  
  Volume: 110 Issue: 1 Pages: 6-15
- DOI
  10.1111/cas.13837
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04123
[Journal Article] The role of sphingosine-1-phosphate in inflammation and cancer progression2018
- Author(s)
  Nagahashi Masayuki、Abe Manabu、Sakimura Kenji、Takabe Kazuaki、Wakai Toshifumi
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 12 Pages: 3671-3678
- DOI
  10.1111/cas.13802
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19576
[Journal Article] 1.ABCC1-Exported Sphingosine-1-phosphate, Produced by Sphingosine Kinase 1, Shortens Survival of Mice and Patients with Breast Cancer2018
- Author(s)
  Yamada A, Nagahashi M, Aoyagi T, Huang WC, Lima S, Hait NC, Maiti A, Kida K, Terracina KP, Miyazaki H, Ishikawa T, Endo I, Waters MR, Qi Q, Yan L, Milstien S, Spiegel S, Takabe K.
- Journal Title
  
  Mol Cancer Res
  
  Volume: 印刷中 Issue: 6 Pages: 1059-1070
- DOI
  10.1158/1541-7786.mcr-17-0353
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19055, KAKENHI-PROJECT-15H05676
[Journal Article] Feasibility of restorative proctocolectomy in patients with ulcerative colitis-associated lower rectal cancer: A retrospective study.2018
- Author(s)
  Hotta S, Shimada Y, Nakano M, Yamada S, Abe K, Oyanagi H, Yagi R, Tajima Y, Nakano M, Kameyama H, Nagahashi M, Sakata J, Kobayashi T, Wakai T.
- Journal Title
  
  Asian Journal of Surgery
  
  Volume: 印刷中
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10624
[Journal Article] Ceramide species are elevated in human breast cancer and are associated with less aggressiveness2018
- Author(s)
  Moro K, Kawaguchi T, Tsuchida J, Gabriel E, Qi Q, Yan L, Wakai T, Takabe K, Nagahashi M
- Journal Title
  
  Oncotarget
  
  Volume: 印刷中
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15471
[Journal Article] Hypermutation and microsatellite instability in gastrointestinal cancers2017
- Author(s)
  Yuza Kizuki、Nagahashi Masayuki、Watanabe Satoshi、Takabe Kazuaki、Wakai Toshifumi
- Journal Title
  
  Oncotarget
  
  Volume: 8 Issue: 67 Pages: 112103-112115
- DOI
  10.18632/oncotarget.22783
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10579
[Journal Article] Doxorubicin effect is enhanced by sphingosine-1-phosphate signaling antagonist in breast cancer2017
- Author(s)
  Katsuta Eriko、Yan Li、Nagahashi Masayuki、Raza Ali、Sturgill Jamie L.、Lyon Debra E.、Rashid Omar M.、Hait Nitai C.、Takabe Kazuaki
- Journal Title
  
  Journal of Surgical Research
  
  Volume: 219 Pages: 202-213
- DOI
  10.1016/j.jss.2017.05.101
- Data Source
  KAKENHI-PROJECT-15K15471
[Journal Article] 癌と宿主におけるスフィンゴシン-1-リン酸の役割2017
- Author(s)
  永橋　昌幸，若井　俊文
- Journal Title
  
  BIO Clinica
  
  Volume: 32 Pages: 397-404
- Data Source
  KAKENHI-PROJECT-15H04927
[Journal Article] Clinical Impact of Sphingosine-1-Phosphate in Breast Cancer2017
- Author(s)
  Tsuchida Junko、Nagahashi Masayuki、Takabe Kazuaki、Wakai Toshifumi
- Journal Title
  
  Mediators of Inflammation
  
  Volume: 2017 Pages: 1-9
- DOI
  10.1155/2017/2076239
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19888, KAKENHI-PROJECT-15H05676
[Journal Article] Intravenous Carnitine Administration in Addition to Parenteral Nutrition with Lipid Emulsion may Decrease the Inflammatory Reaction in Postoperative Surgical Patients.2017
- Author(s)
  KoyamaY, Moro K, Nakano M, Miura K, Nagahashi M, Kosugi S-I, Tsuchida J, Ikarashi M, Nakajima M, Ichikawa H, Hanyu T, Shimada Y, Jun Sakata J, Kameyama H, Kobayashi T, Wakai T.
- Journal Title
  
  Journal of Clinical Medicine Research
  
  Volume: 9 Issue: 10 Pages: 831-837
- DOI
  10.14740/jocmr3113w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10047
[Journal Article] Clinical significance of NQO1 expression in patients with advanced KRAS wild colorectal cancer2017
- Author(s)
  Hitoshi Kameyama, Yuki Hirose, Yasunobu Matsuda, Masayuki Nagahashi, Hiroshi Ichikawa, You Sato, Saki Yamada, Shinnosuke Hotta, Yosuke Tajima, Takuma Okamura, Mae Nakano, Masato Nakano, Yoshifumi Shimada, Jun Sakata, Takashi Kobayashi, Toshifumi Wakai
- Journal Title
  
  Int J Clin Exp Pathol
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462006
[Journal Article] The role of sphingosine-1-phosphate in the tumor microenvironment and its clinical implications2017
- Author(s)
  Nakajima M, Nagahashi M, Rashid OM, Takabe K, Wakai T
- Journal Title
  
  Tumour Biol.
  
  Volume: 39 Issue: 4 Pages: 101042-101042
- DOI
  10.1177/1010428317699133
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04927, KAKENHI-PROJECT-16K15610, KAKENHI-PROJECT-15H05676
[Journal Article] The role of sphingosine 1-phosphate receptor 2 in bile-acid-induced cholangiocyte proliferation and cholestasis-induced liver injury in mice2017
- Author(s)
  Wang Y, Aoki H, Yang J, Peng K, Liu R, Li X, Qiang X, Sun L, Gurley EC, Lai G, Zhang L, Liang G, Nagahashi M, Takabe K, Pandak WM, Hylemon PB, Zhou H.
- Journal Title
  
  Hepatology
  
  Volume: 印刷中 Issue: 6 Pages: 2005-2018
- DOI
  10.1002/hep.29076
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15471, KAKENHI-PROJECT-16K15610
[Journal Article] Bile acids as global regulators of hepatic nutrient metabolism.2017
- Author(s)
  Hylemon PB, Takabe K, Dozmorov M, Nagahashi M, Zhou H
- Journal Title
  
  Liver Res.
  
  Volume: 1 Issue: 1 Pages: 10-16
- DOI
  10.1016/j.livres.2017.03.002
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15610, KAKENHI-PROJECT-15K15471
[Journal Article] 癌と宿主におけるスフィンゴシン-1-リン酸の役割2017
- Author(s)
  永橋　昌幸，若井　俊文
- Journal Title
  
  BIO Clinica
  
  Volume: 32 Pages: 397-404
- Data Source
  KAKENHI-PROJECT-15H05676
[Journal Article] 癌と宿主におけるスフィンゴシン-1-リン酸の役割2017
- Author(s)
  永橋昌幸、若井俊文
- Journal Title
  
  BIO Clinica
  
  Volume: 32 Pages: 397-404
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K15610
[Journal Article] The roles of bile acids and sphingosine-1-phosphate signaling in the hepatobiliary diseases.2016
- Author(s)
  Nagahashi M, Yuza K, Hirose Y, Nakajima M, Ramanathan R, Hait NC, Hylemon PB, Zhou H, Takabe K, Wakai T.
- Journal Title
  
  J Lipid Res.
  
  Volume: 57 Issue: 9 Pages: 1636-43
- DOI
  10.1194/jlr.r069286
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04927, KAKENHI-PROJECT-15K15471, KAKENHI-PROJECT-16K15610
[Journal Article] Interstitial Fluid Sphingosine-1-Phosphate in Murine Mammary Gland and Cancer and Human Breast Tissue and Cancer Determined by Novel Methods.2016
- Author(s)
  Nagahashi M, Yamada A, Miyazaki H, Allegood JC, Tsuchida J, Aoyagi T, Huang WC, Terracina KP, Adams BJ, Rashid OM, Milstien S, Wakai T, Spiegel S, Takabe K.
- Journal Title
  
  J Mammary Gland Biol Neoplasia
  
  Volume: 21 Issue: 1-2 Pages: 9-17
- DOI
  10.1007/s10911-016-9354-7
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04927, KAKENHI-PROJECT-15H05676, KAKENHI-PROJECT-16K19055, KAKENHI-PROJECT-16K19888
[Journal Article] 脂質メディエーターを介した胆汁酸シグナル伝達系の役割2016
- Author(s)
  永橋昌幸, 大橋拓, 滝沢一泰, 坂田純, 小林隆, 若井俊文
- Journal Title
  
  胆道
  
  Volume: 30 Pages: 220-227
- NAID
  130005157398
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K15610
[Journal Article] Sphingosine-1-phosphate phosphatase 2 promotes disruption of mucosal integrity, and contributes to ulcerative colitis in mice and humans2016
- Author(s)
  Huang WC, Liang J, Nagahashi M, Avni D, Yamada A, Maceyka M, Wolen AR, Kordula T, Milstien S, Takabe K, Oravecz T, Spiegel S
- Journal Title
  
  FASEB J
  
  Volume: 30 Issue: 8 Pages: 2945-2958
- DOI
  10.1096/fj.201600394r
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05676, KAKENHI-PROJECT-16K19055
[Journal Article] Breast cancer sphingosine-1-phosphate is associated with phospho-sphingosine kinase 1 and lymphatic metastasis2016
- Author(s)
  Tsuchida J, Nagahashi M, Nakajima M, Moro K, Tatsuda K, Ramanathan R, Takabe K, Wakai T
- Journal Title
  
  J Surg Res
  
  Volume: 205 Issue: 1 Pages: 85-94
- DOI
  10.1016/j.jss.2016.06.022
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05676, KAKENHI-PROJECT-16K19888
[Journal Article] DNA damage response and sphingolipid signaling in liver diseases.2016
- Author(s)
  Masayuki Nagahashi, Yasunobu Matsuda, Kazuki Moro, Daiki Soma, Junko Tsuchida, Yuki Hirose, Takashi Kobayashi, Shin-ichi Kosugi, Kazuaki Takabe, Masaaki Komatsu, Toshifumi Wakai
- Journal Title
  
  Surgery Today
  
  Volume: 未定
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K15471
[Journal Article] Surgical and long-term outcomes following oesophagectomy in oesophageal cancer patients with comorbidity2016
- Author(s)
  Ichikawa H, Kosugi SI, Kanda T, Yajima K, Ishikawa T, Hanyu T, Muneoka Y, Otani T, Nagahashi M, Sakata J, Kobayashi T, Kameyama H, Wakai T
- Journal Title
  
  International Journal of Surgery
  
  Volume: 36 Pages: 212-218
- DOI
  10.1016/j.ijsu.2016.10.041
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K10491
[Journal Article] Sphingosine-1-phosphate in the lymphatic fluid determined by novel methods.2016
- Author(s)
  Nagahashi M, Yamada A, Aoyagi T, Allegood J, Wakai T, Spiegel S, Takabe K
- Journal Title
  
  Heliyon
  
  Volume: 2 Issue: 12 Pages: e00219-e00219
- DOI
  10.1016/j.heliyon.2016.e00219
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04927, KAKENHI-PROJECT-15H05676, KAKENHI-PROJECT-16K15610, KAKENHI-PROJECT-16K19055
[Journal Article] Low fat-containing elemental formula is effective for postoperative recovery and potentially useful for preventing chyle leak during postoperative early enteral nutrition after esophagectomy.2016
- Author(s)
  Moro K, Koyama Y, Kosugi SI, Ishikawa T, Ichikawa H, Hanyu T, Miura K, Nagahashi M, Nakajima M, Tatsuda K, Tsuchida J, Toshikawa C, Ikarashi M, Shimada Y, Sakata J, Kobayashi T, Kameyama H, Wakai T
- Journal Title
  
  Clinical Nutrition
  
  Volume: 35 Issue: 6 Pages: 1423-1428
- DOI
  10.1016/j.clnu.2016.03.018
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K10047, KAKENHI-PROJECT-16K10491
[Journal Article] 脂質メディエーターを介した胆汁酸シグナル伝達系の役割2016
- Author(s)
  永橋昌幸, 大橋拓, 滝沢一泰, 坂田純, 小林隆, 若井俊文
- Journal Title
  
  胆道
  
  Volume: 未定
- NAID
  130005157398
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15471
[Journal Article] Prognostic significance of NQO1 expression in esophageal squamous cell carcinoma after preoperative chemotherapy with cisplatin and 5-fluorouracil followed by curative esophagectomy2016
- Author(s)
  Ichikawa H, Kosugi S, Hirose Y, Matsuda Y, Ishikawa T, Hanyu T, Usui K, Muneoka Y, Nagahashi M, Sakata J, Kobayashi T, Kameyama H, Wakai T
- Journal Title
  
  International Journal of Clinical and Experimental Pathology
  
  Volume: 9 Pages: 7393-7401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10491
[Journal Article] High levels of sphingolipids in human breast cancer2016
- Author(s)
  Nagahashi M, Tsuchida J, Moro K, Hasegawa M, Tatsuda K, Woelfel IA, Takabe K, Wakai T
- Journal Title
  
  J Surg Res
  
  Volume: 204 Issue: 2 Pages: 435-444
- DOI
  10.1016/j.jss.2016.05.022
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05676, KAKENHI-PROJECT-16K19888
[Journal Article] Resolvins and omega three polyunsaturated fatty acids: Clinical implications in inflammatory diseases and cancer.2016
- Author(s)
  Moro K, Nagahashi M, Ramanathan R, Takabe K, Wakai T.
- Journal Title
  
  World J Clin Cases.
  
  Volume: 4 Issue: 7 Pages: 155-64
- DOI
  10.12998/wjcc.v4.i7.155
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04927, KAKENHI-PROJECT-15K15471
[Journal Article] Sphingosine-1-phosphate phosphatase 2 promotes disruption of mucosal integrity, and contributes to ulcerative colitis in mice and humans2016
- Author(s)
  Wei-Ching Huang, Jie Liang, Masayuki Nagahashi, Dorit Avni, Akimitsu Yamada, Michael Maceyka, Aaron R. Wolen, Tomasz Kordula, Sheldon Milstien, Kazuaki Takabe, Tamas Oravecz, Sarah Spiegel
- Journal Title
  
  The FASEB Journal
  
  Volume: 未定
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05676
[Journal Article] DNA damage response and sphingolipid signaling in liver diseases2016
- Author(s)
  Nagahashi M, Matsuda Y, Moro K, Tsuchida J, Soma D, Hirose Y, Kobayashi T, Kosugi SI, Takabe K, Komatsu M, Wakai T
- Journal Title
  
  Surg Today
  
  Volume: 印刷中 Issue: 9 Pages: 995-1005
- DOI
  10.1007/s00595-015-1270-8
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04927, KAKENHI-PROJECT-15K15471, KAKENHI-PROJECT-16K15610
[Journal Article] 脂質メディエーターを介した胆汁酸シグナル伝達系の役割2016
- Author(s)
  永橋　昌幸，大橋　拓，滝沢　一泰，坂田　純，小林　隆，若井　俊文
- Journal Title
  
  胆道
  
  Volume: 30 Pages: 220-227
- NAID
  130005157398
- Data Source
  KAKENHI-PROJECT-15K15471
[Journal Article] 癌における脂質メディエーター・スフィンゴシン-1-リン酸の働き2015
- Author(s)
  永橋　昌幸
- Journal Title
  
  新潟県医師会報
  
  Volume: 789 Pages: 1-7
- Data Source
  KAKENHI-PROJECT-15H05676
[Patent] 変異型ヒトＤＮＡポリメラーゼε2021
- Inventor(s)
  若井俊文、亀山仁史、永橋昌幸、島田能史、市川　寛
- Industrial Property Rights Holder
  若井俊文、亀山仁史、永橋昌幸、島田能史、市川　寛
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Acquisition Date
  2024
- Data Source
  KAKENHI-PROJECT-21H02998
[Presentation] Targeting S1P signaling pathway in triple negative breast cancer with TP53 mutations.2024
- Author(s)
  Masayuki Nagahashi, Miki Komatsu, Sayaka Urano, Mamiko Kuroiwa, Yasuo Miyoshi
- Organizer
  第21回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-21K19522
[Presentation] Correlation of mutational signature between whole genome sequencing and gene panel tests in colorectal cancer2023
- Author(s)
  廣瀬雄己，島田能史，田島陽介，阿部　馨，松本瑛生，大関　瑛，土田純子，諸　和樹，宗岡悠介，市川　寛，竹内志穂，永橋昌幸，坂田　純，奥田修二郎，若井俊文
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08750
[Presentation] 進行・再発乳癌に対するエリブリン治療におけるIL-6の臨床的意義と関連因子について2023
- Author(s)
  文亜也子、永橋昌幸、福井玲子、藤本由希枝、樋口智子、阿竹優紗、服部彬、尾澤宏美、村瀬慶子、高塚雄一、三好康雄
- Organizer
  第31回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K08764
[Presentation] Immune related cell fraction in peripheral blood and outcomes of advanced breast cancer patients treated with Eribulin2023
- Author(s)
  Masayuki Nagahashi, Ayako Bun, Mamiko Kuroiwa, Miki Komatsu, Sayaka Urano, Yukie Fujimoto, Aoi Oshiro, Ayumu Mitsuyoshi, Haruka Kanaoka, Akira Hattori, Reiko Fukui, Tomoko Higuchi, Arisa Nishimukai, Keiko Murase, Yuichi Takatsuka, Yasuo Miyoshi.
- Organizer
  San Antonio Breast Cancer Symposium 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08764
[Presentation] 乳癌における脂質メディエーターの役割と臨床応用へ向けた取り組み2023
- Author(s)
  永橋　昌幸，服部　彬，浦野　清香，黒岩　真美，小松　美希，三好　康雄
- Organizer
  第31回乳癌基礎研究会
- Data Source
  KAKENHI-PROJECT-23K24399
[Presentation] 乳癌患者における血漿中スフィンゴ脂質の質量分析と臨床病理学的因子との関連2023
- Author(s)
  服部　　彬、永橋　昌幸、阿竹　優紗、文　亜也子、福井　玲子、藤本由希枝、樋口　智子、村瀬　慶子、高塚　雄一、三好　康雄
- Organizer
  第31回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24399
[Presentation] 当研究室における乳癌患者検体からのオルガノイド樹立2023
- Author(s)
  小松　美希、永橋　昌幸、浦野　清香、黒岩真美子、三好　康雄
- Organizer
  第31回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24399
[Presentation] 脂質メディエーターを標的とする薬物送達システムを用いた新規乳癌治療薬の開発2023
- Author(s)
  永橋　昌幸，田中　克典，プラディプタアンバラ，盛本　浩二，寺島　一輝，高橋　ゆりあ，浦野　清香，黒岩　真美子，小松　美希，三好　康雄
- Organizer
  第31回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24399
[Presentation] The role of sphingolipids in cancer progression and its microenvironment in breast cancer patients2023
- Author(s)
  Akira Hattori, Masayuki Nagahashi, Aoi Oshiro, Ayumu Mitsuyoshi, Haruka Kanaoka, Ayako Bun, Reiko fukui, Yukie Fujimoto, Tomoko Higuchi, Arisa Nishimukai, Keiko Murase, Yuichi Takatsuka, Yasuo Miyoshi
- Organizer
  San Antonio Breast Cancer Symposium 2023
- Data Source
  KAKENHI-PROJECT-23K24399
[Presentation] 進行・再発乳癌におけるエリブリンの治療効果と相関する末梢血中バイオマーカーの同定2022
- Author(s)
  文　亜也子、永橋　昌幸、金岡　遥、福井　玲子、尾澤　宏美、藤本　由希枝、樋口　智子、今村　美智子、村瀬　慶子、高塚　雄一、三好　康雄
- Organizer
  第30回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K08764
[Presentation] COPY number alterations is an independent prognostic biomarker in triple-negative breast cancer patients2022
- Author(s)
  Nagahashi M, Ling Y, Toshikawa C, Hayashida T, Kitagawa Y, Futamura M, Kuwayama T, Nakamura S, Yamauchi H, Yamauchi T, Kaneko K, Kanbayashi C, Sato N, Tsuchida J, Moro K, Nakajima M, Shimada Y, Ichikawa H, Lyle S, Miyoshi Y, Takabe K, Okuda S, Wakai T.
- Organizer
  2022 San Antonio Breast Cancer Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24399
[Presentation] Clinical Significance of the Expression of Phosphorylated Sphingosine Kinase1 in Pancreatic cancer2022
- Author(s)
  Kazuyasu Takizawa, Hiroki Nagaro, Jun Sakata, Hiroshi Ichikawa, Masayuki Nagahashi, Yoshifumi Shimada, Takashi Kobayashi, Toshifumi Wakai
- Organizer
  The 17th Annual Academic Surgical Congress (ASC)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09099
[Presentation] 癌微小環境における脂質メディエーター・スフィンゴシン-1-リン酸の役割2022
- Author(s)
  永橋　昌幸、三好　康雄
- Organizer
  第60回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24399
[Presentation] 肥満状態下の乳癌転移におけるスフィンゴシン-1-リン酸の役割2021
- Author(s)
  永橋　昌幸，土田　純子，諸　和樹，長谷川　遙，小幡　泰生，遠藤　麻巳子，利川　千絵，五十嵐　麻由子，小山　諭，高部　和明，若井　俊文
- Organizer
  第29回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03714
[Presentation] Actionable gene alterations in Japanese patients with triple-negative breast cancer2021
- Author(s)
  永橋　昌幸
- Organizer
  第121回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-21K19522
[Presentation] Gene panel testing as a clinical application for detecting HER2 alterations in gastric cancer2020
- Author(s)
  Hiroshi Ichikawa, Kenji Usui, Yoshifumi Shimada, Yusuke Muneoka, Takaaki Hanyu, Yosuke Kano, Takashi Ishikawa, Kohei Miura, Masayuki Nagahashi, Jun Sakata, Takashi Kobayashi, Hiroshi Yabusaki, Satoru Nakagawa, Hitoshi Kameyama, Shujiro Okuda, Toshifumi Wakai
- Organizer
  15th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09117
[Presentation] Involvement of sphingosine-1-phosphate in tumor immune microenvironment of breast cancer patients2020
- Author(s)
  Junko Tsuchida, Masayuki Nagahashi, Mayuko Ikarashi, Kazuki Moro, Chie Toshikawa, Hiroshi Ichikawa, Yoshifumi Shimada, Kazuaki Takabe, Toshifumi Wakai
- Organizer
  The 15th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10538
[Presentation] Association between estrogen receptor status and plasma S1P levels in breast cancer patients2020
- Author(s)
  Masayuki Nagahashi, Junko Tsuchida, Mayuko Ikarashi, Kazuki Moro, Chie Toshikawa, Hiroshi Ichikawa, Yoshifumi Shimada, Kazuaki Takabe, Toshifumi Wakai
- Organizer
  The 15th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10538
[Presentation] 乳癌微小環境における組織間質液中のスフィンゴリン脂質定量の試み2020
- Author(s)
  永橋昌幸，土田純子，諸　和樹，遠藤麻巳子，庭野稔之，山浦久美子，利川千絵，長谷川美樹，五十嵐麻由子，中島真人，小山　諭，高部和明，若井俊文
- Organizer
  第28回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K19576
[Presentation] Association between MSI using oncogene panel for gastric cancer and mismatch repair gene expression2020
- Author(s)
  Takaaki Hanyu, Hiroshi Ichikawa, Yosuke Kano, Takashi Ishikawa, Yusuke Muneoka, Daisuke Motegi, Yoshifumi Shimada, Masayuki Nagahashi, Jun Sakata, Toshifumi Wakai
- Organizer
  第93回日本胃癌学会総会
- Data Source
  KAKENHI-PROJECT-19K09165
[Presentation] 慢性炎症による癌の増殖・転移を促進する脂質メディエーター分子機構2020
- Author(s)
  永橋　昌幸，土田　純子，油座　築，諸　和樹，根本　万里子，廣瀬　雄己，利川　千絵，五十嵐　麻由子，三浦　宏平，市川　寛，羽入　隆晃，滝沢　一泰，中島　真人，島田　能史，小林　隆，坂田　純，石川　卓，亀山　仁史，若井　俊文
- Organizer
  第120回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-19H03714
[Presentation] 慢性炎症による癌の増殖・転移を促進する脂質メディエーター分子機構2020
- Author(s)
  永橋昌幸, 土田純子, 油座築, 諸和樹, 根本万里子, 廣瀬雄己, 利川千絵, 五十嵐麻由子, 三浦宏平, 田島陽介, 市川寛, 羽入隆晃, 滝沢一泰, 中島真人, 島田能史, 小林隆, 坂田純, 石川卓, 亀山仁史, 若井俊文
- Organizer
  第120回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-20K09074
[Presentation] Association between estrogen receptor status and plasma S1P levels in breast cancer patients2020
- Author(s)
  Masayuki Nagahashi, Junko Tsuchida, Mayuko Ikarashi, Kazuki Moro, Chie Toshikawa, Hiroshi Ichikawa, Yoshifumi Shimada, Kazuaki Takabe, Toshifumi Wakai
- Organizer
  The 15th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19576
[Presentation] Involvement of sphingosine-1-phosphate in tumor immune microenvironment of breast cancer patients2020
- Author(s)
  Junko Tsuchida, Masayuki Nagahashi, Mayuko Ikarashi, Kazuki Moro, Chie Toshikawa, Hiroshi Ichikawa, Yoshifumi Shimada, Kazuaki Takabe, Toshifumi Wakai
- Organizer
  The 15th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03714
[Presentation] 次世代シークエンサーを用いた遺伝子検査とゲノム解析データベース構築2019
- Author(s)
  永橋昌幸、若井俊文、島田能史、市川寛、羽入隆晃、滝沢一泰、石川卓、坂田純、小林隆、亀山仁史、竹内志穂、奥田修二郎
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H04123
[Presentation] リン酸化抗体を用いた免疫組織化学による消化器癌の脂質メディエーター解析研究2019
- Author(s)
  永橋昌幸, 油座築, 廣瀬雄己, 市川寛, 羽入隆晃, 島田能史, 小林隆, 坂田純, 亀山仁史, 若井俊文
- Organizer
  第74回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-17K10624
[Presentation] 大腸癌のPrecision medicineの現状と展望　大腸癌診療における遺伝子パネル検査の可能性2019
- Author(s)
  島田能史, 永橋昌幸, 市川寛, 田島陽介, 中野雅人, 阿部馨, 田中花菜, 小柳英人, 諸和樹, 滝沢一泰, 羽入隆晃, 廣瀬雄己, 三浦宏平, 小林隆, 坂田純, 亀山仁史, 野上仁, 丸山聡, 瀧井康公, 若井俊文
- Organizer
  第74回日本大腸肛門病学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10624
[Presentation] 固形癌における包括的ゲノム解析に基づくPrecision Medicine2019
- Author(s)
  若井俊文、島田能史、永橋昌幸、市川寛、油座築、根本万里子、中野麻恵、廣瀬雄己、滝沢一泰、坂田純、亀山仁史、小林隆、棗田学、吉原弘祐、奥田修二郎
- Organizer
  第57回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18H04123
[Presentation] Levels of sphingolipids in plasma are elevated in breast cancer patients with lymph node metastasis2019
- Author(s)
  Junko Tsuchida, Masayuki Nagahashi, Kazuki Moro, Mayuko Ikarashi, Yu Koyama, Jun Sakata, Takashi Kobayashi, Hitoshi Kameyama, Kazuaki Takabe, Toshifumi Wakai
- Organizer
  The 14th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10538
[Presentation] 乳癌患者における血漿中スフィンゴシン-1-リン酸濃度の臨床的意義2019
- Author(s)
  五十嵐　麻由子，永橋　昌幸，土田　純子，遠藤　麻巳子，諸　和樹，庭野　稔之，山浦　久美子，利川　千絵，長谷川　美樹，中島　真人，小山　諭，若井　俊文
- Organizer
  第27回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10538
[Presentation] Genomic alteration spectrum and future direction of targeted therapy for gastric cancer2019
- Author(s)
  Hiroshi Ichikawa, Hiroshi Yabusaki, Takaaki Hanyu, Yoshifumi Shimada, Masayuki Nagahashi, Jun Sakata, Takashi Kobayashi, Satoru Nakagawa, Hitoshi Kameyama, Toshifumi Wakai
- Organizer
  第74回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-19K09165
[Presentation] リン酸化抗体を用いた免疫組織化学による消化器癌の脂質メディエーター解析研究2019
- Author(s)
  永橋　昌幸，油座　築，廣瀬　雄己，市川　寛，羽入　隆晃，島田　能史，小林　隆，坂田　純，亀山　仁史，若井　俊文
- Organizer
  第74回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-17K10692
[Presentation] Genomic alteration spectrum and future direction of targeted therapy for gastric cancer2019
- Author(s)
  Hiroshi Ichikawa, Hiroshi Yabusaki, Takaaki Hanyu, Yoshifumi Shimada, Masayuki Nagahashi, Jun Sakata, Takashi Kobayashi, Satoru Nakagawa, Hitoshi Kameyama, Toshifumi Wakai
- Organizer
  第74回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-19K09117
[Presentation] Genomic alteration spectrum and future direction of targeted therapy for gastric cancer2019
- Author(s)
  Hiroshi Ichikawa, Hiroshi Yabusaki, Takaaki Hanyu, Yoshifumi Shimada, Masayuki Nagahashi, Jun Sakata, Takashi Kobayashi, Satoru Nakagawa, Hitoshi Kameyama, Toshifumi Wakai
- Organizer
  第74回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-18K08698
[Presentation] Defective Homologous Recombination in Platinum-based Chemotherapy for Gastric Cancer2019
- Author(s)
  T. Katada, H. Ichikawa, Y. Hirose, M. Nagahashi, Y. Shimada, T. Hanyu, T. Ishikawa, Y. Kano, Y. Muneoka, J. Sakata, T. Kobayashi, H. Kameyama, T. Wakai
- Organizer
  14th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08698
[Presentation] Sphingosine-1-phospate Signaling Regulates Drug Resistance Mediated by Glutathione2019
- Author(s)
  Nagahashi M, Tsuchida J, Moro K, Ikarashi M, Nakajima M, Abe M, Saito T, Komatsu M, Soga T, Takabe K, Sakimura K, Wakai T
- Organizer
  The 14th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19576
[Presentation] 切除不能大腸癌に対するConversion Surgeryの現状　切除不能大腸癌のConversion Surgeryにおける遺伝子パネル検査の意義2019
- Author(s)
  島田能史, 中野雅人, 市川寛, 永橋昌幸, 羽入隆晃, 小林隆, 坂田純, 亀山仁史, 瀧井康公, 若井俊文
- Organizer
  第74回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-17K10624
[Presentation] Tumor location and alteration spectrum of actionable genes in gastroesophageal cancer2019
- Author(s)
  Hiroshi Ichikawa, Yoshifumi Shimada, Masayuki Nagahashi, Takaaki Hanyu, Yosuke Kano, Yusuke Muneoka, Takashi Ishikawa, Yuki Hirose, Kohei Miura, Jun Sakata, Takashi Kobayashi, Satoru Nakagawa, Hiroshi Yabusaki, Hitoshi Kameyama, Toshifumi Wakai
- Organizer
  第57回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09165
[Presentation] Sphingosine-1-phospate signaling regulates drug resistance mediated by glutathione2019
- Author(s)
  Nagahashi M, Tsuchida J, Moro K, Ikarashi M, Nakajima M, Abe M, Saito T, Komatsu M, Soga T, Takabe K, Sakimura K, Wakai T
- Organizer
  The 14th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10538
[Presentation] 大腸癌Hypermutationの臨床病理学的特徴(Clinicopathological features of hypermutation in colorectal cancer)2019
- Author(s)
  島田能史, 田島陽介, 小柳英人, 永橋昌幸, 市川寛, 中野麻恵, 中野雅人, 諸和樹, 坂田純, 小林隆, 亀山仁史, 奥田修二郎, 若井俊文
- Organizer
  第78回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-17K10624
[Presentation] Breast Cancer Cell Metabolism Is Regulated by Sphingosine Kinases2018
- Author(s)
  Nagahashi M, Nakajima M, Abe M, Saito T, Komatsu M, Soga T, Tsuchida J, Yuza K, Takabe K, Sakimura K, Wakai T
- Organizer
  The 13th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15471
[Presentation] High levels of sphingolipids in human pancreatic cancer2018
- Author(s)
  K. Yuza, M. Nagahashi, Y. Hirose, M. Nakajima, K. Miura, H. Ichikawa, Y. Shimada, J. Sakata, H. Kameyama, T. Kobayashi, K. Takabe, T. Wakai
- Organizer
  The 13th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04927
[Presentation] Sphingosine-1-phosphate produced by sphingosine kinase type 1 and type 2 works differently in pancreatic cancer2018
- Author(s)
  M. Nakajima, K. Yuza, J. Tsuchida, Y. Hirose, K. Miura, H. Ichikawa, Y. Shimada, T. Kobayashi, J. Sakata, H. Kameyama, M. Abe, K. Sakimura, T. Wakai, M. Nagahashi
- Organizer
  The 13th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04927
[Presentation] High Expression of Sphingosine Kinase 1 in Colitis-Associated Cancer2018
- Author(s)
  Yuza K, Nagahashi M, Shimada Y, Nakano M, Tajima Y, Kameyama H, Nakajima M, Ichikawa H, Sakata J, Kobayashi T, Takabe K, Wakai T
- Organizer
  13th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10491
[Presentation] ヒト胆道癌組織における脂質メディエーターS1Pの発現とその意義2018
- Author(s)
  廣瀬雄己, 永橋昌幸, 油座築, 安藤拓也, 相馬大輝, 諸和樹, 峠弘治, 石川博補, 堅田朋大, 三浦宏平, 市川寛, 滝沢一泰, 中島真人, 島田能史, 坂田純, 小林隆, 亀山仁史, 若井俊文
- Organizer
  第118回日本外科学会定期学術集会（東京都）
- Data Source
  KAKENHI-PROJECT-16K15610
[Presentation] The roles of sphingosine-1-phosphate produced by sphingosine kinases in tumor and its microenvironment2018
- Author(s)
  Miura K, Nagahashi M, Nakajima M, Yuza K, Tsuchida J, Hirose Y, Abe M, Sakimura K, Wakai T
- Organizer
  The 13th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05676
[Presentation] シンポジウム 5　ゲノム医療推進に向けた取り組みの課題と展望　当科におけるゲノム医療推進に向けた取組み2018
- Author(s)
  永橋　昌幸，土田　純子，遠藤　麻巳子，諸　和樹，庭野　稔之，山浦　久美子，利川　千絵，長谷川　美樹，五十嵐　麻由子，中島　真人，小山　諭，神林　智寿子，金子　耕司，佐藤　信昭，若井　俊文
- Organizer
  第26回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K19576
[Presentation] The Significance of Phospho-Sphingosine Kinase 1 in the Lymphatic Spread of Esophageal Carcinoma2018
- Author(s)
  Ichikawa H, Nagahashi M, Nemoto M, Hanyu T, Ishikawa T, Kano Y, Muneoka Hirose Y, Shimada Y, Sakata J, Kobayashi T, Kameyama H, Kazuaki T, Wakai T
- Organizer
  13th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10491
[Presentation] High Levels of Sphingolipids in Human Pancreatic Cancer2018
- Author(s)
  Yuza K, Nagahashi M, Hirose Y, Nakajima M, Miura K, Ichikawa H, Shimada Y, Sakata J, Kameyama H, Kobayashi T, Takabe K, Wakai T
- Organizer
  13th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10491
[Presentation] 食道扁平上皮癌リンパ行性進展におけるphospho-sphingosine kinase 1発現の意義2018
- Author(s)
  市川　寛，根本　万理子，石川　卓，羽入　隆晃，角田　知行，須藤　翔，島田　能史，永橋　昌幸，坂田　純，小林　隆，亀山　仁史，若井　俊文
- Organizer
  第118回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-16K10491
[Presentation] 潰瘍性大腸炎関連大腸癌診断における脂質メディエーター(S1P)解析の有用性2018
- Author(s)
  亀山仁史，永橋昌幸，油座　築，田島陽介，羽入隆晃，中野雅人，中島真人，島田能史，坂田　純，若井俊文
- Organizer
  第73回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-17K10624
[Presentation] Dysregulation of Sphingolipids in Human Hepatocellular Carcinoma2018
- Author(s)
  Miura K, Nagahashi M, Hirose Y, Kobayashi T, Sakata J, Kameyama H, Shimada Y, Ichikawa H, Takabe K, Wakai T
- Organizer
  13th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10491
[Presentation] Sphingosine Kinase Type 1 and Type 2 Works Differently in Pancreatic Cancer2018
- Author(s)
  Nakajima M, Yuza K, Tsuchida J, Hirose Y, Miura K, Ichikawa H, Shimada Y, Kobayashi T, Sakata J, Kameyama H, Abe M, Sakimura K, Wakai T, Nagahashi M
- Organizer
  13th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10491
[Presentation] Dysregulation of Sphingolipids in Human Hepatocellular Carcinoma2018
- Author(s)
  K. Miura, M. Nagahashi, Y. Hirose, T. Kobayashi, J. Sakata, H. Kameyama, Y. Shimada, H. Ichikawa, K. Takabe, T. Wakai
- Organizer
  The 13th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15610
[Presentation] Ceramide species are elevated with activation of ceramide biosynthesis pathways in human breast cancer2018
- Author(s)
  Moro K, Kawaguchi T, Tsuchida J, Gabriel E, Qi Q, Yan L, Sato N, Wakai T, Takabe K, Nagahashi M
- Organizer
  The 13th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15471
[Presentation] High Expression of Sphingosine Kinase 1 in Colitis-Associated Cancer2018
- Author(s)
  Yuza K, Nagahashi M, Shimada Y, Nakano M, Tajima Y, Kameyama H, Nakajima M, Ichikawa H, Sakata J, Kobayashi T, Takabe K, Wakai T
- Organizer
  14th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10624
[Presentation] Human Biliary Tract Cancer Contains High Levels of S1P2018
- Author(s)
  Hirose Y, Nagahashi M, Yuza K, Miura K, Sakata J, Kobayashi T, Ichikawa H, Shimada Y, Kameyama H, Takabe K, Wakai T
- Organizer
  13th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10491
[Presentation] 潰瘍性大腸炎に合併した大腸癌（colitic cancer）におけるリン酸化スフィンゴシンキナーゼ1高発現の意義2018
- Author(s)
  油座　築、永橋昌幸、島田能史、中野麻恵、田島陽介、亀山仁史、中島真人、市川　寛、坂田　純、小林　隆、高部和明、若井俊文
- Organizer
  第118回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-17K10624
[Presentation] 肥満が引き起こす慢性炎症による乳癌の転移促進と脂質メディエーターの役割2018
- Author(s)
  永橋　昌幸，土田　純子，油座　築，中島　真人，高部　和明，若井　俊文
- Organizer
  第25回外科侵襲とサイトカイン研究会
- Data Source
  KAKENHI-PROJECT-18K19576
[Presentation] 肝細胞癌患者における脂質メディエーター・スフィンゴシン-1-リン酸及びセラミドの定量とその意義2018
- Author(s)
  永橋昌幸, 廣瀬雄己, 三浦宏平, 油座築, 相馬大輝, 安藤拓也, 峠弘治, 石川博輔, 堅田朋大, 坂田純, 小林隆, 中島真人, 羽入隆晃, 市川寛, 石川卓, 島田能史, 亀山仁史, 高部和明, 若井俊文
- Organizer
  日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-18K08672
[Presentation] The Significance of Phospho-Sphingosine Kinase 1 in the Lymphatic Spread of Esophageal Carcinoma2018
- Author(s)
  Hiroshi Ichikawa, Masayuki Nagahashi, Mariko Nemoto, Takaaki Hanyu, Takashi Ishikawa, Yosuke Kano, Yusuke Muneoka, Yoshifumi Shimada, Jun Sakata, Takashi Kobayashi, Hitoshi Kameyama, Toshifumi Wakai
- Organizer
  13th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10491
[Presentation] Human biliary tract cancer contains high levels of S1P2018
- Author(s)
  Yuki Hirose, Masayuki Nagahashi, Kizuki Yuza, Kohei Miura, Jun Sakata, Takashi Kobayashi, Hiroshi Ichikawa, Yoshifumi Shimada, Hitoshi Kameyama, Kazuaki Takabe, Toshifumi Wakai
- Organizer
  The 13th Annual Academic Surgical Congress (Florida, USA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15610
[Presentation] Sphingosine-1-phosphate affects tumor-associated immune cells in human breast cancer patients2018
- Author(s)
  Tsuchida J, Nagahashi M, Moro K, Otani A, Endo M, Ikarashi M, Nakajima M, Koyama Y, Sakata J, Kobayashi T, Kameyama H, Yan Q, Yan L, Takabe K, Wakai T
- Organizer
  The 13th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05676
[Presentation] Human biliary tract cancer contains high levels of S1P2018
- Author(s)
  Y. Hirose, M. Nagahashi, K. Yuza, K. Miura, J. Sakata, T. Kobayashi, H. Ichikawa, Y. Shimada, H. Kameyama, K. Takabe, T. Wakai
- Organizer
  The 13th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15610
[Presentation] リン酸化スフィンゴシンキナーゼ1の発言と胃癌の進行についての関連2018
- Author(s)
  羽入隆晃, 永橋昌幸, 市川寛, 石川卓, 角田知行, 須藤翔, 根本万理子, 小杉伸一, 島田能史, 坂田純, 小林隆, 亀山仁史, 若井俊文
- Organizer
  第118回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-15K10087
[Presentation] Tumor mutation burden in triple negative breast cancer patients in Japan2018
- Author(s)
  Nagahashi M, Ling Y, Hayashida T, Kitagawa Y, Futamura M, Yoshida K, Kuwayama T, Nakamura S, Toshikawa C, Yamauchi H, Yamauchi T, Kaneko K, Kanbayashi C, Sato N, Miyoshi Y, Tsuchida J, Nakajima M, Shimada Y, Ichikawa H, Lyle S, Takabe K, Okuda S, Wakai T
- Organizer
  2018 American Society of Clinical Oncology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19576
[Presentation] Obesity-induced sphingosine-1-phosphate in tumor interstitial fluid promotes angiogenesis and breast cancer progression2018
- Author(s)
  Nagahashi M, Tsuchida J, Moro K, Yuza K, Hirose Y, Ikarashi M, Sakata J, Kobayashi T, Kameyama H, Wakai T, Takabe K
- Organizer
  第１５回臨床腫瘍学会
- Data Source
  KAKENHI-PROJECT-17K10538
[Presentation] 胃癌におけるDNAミスマッチ修復遺伝子変異とアクチビン2型受容体遺伝子変異の検討2017
- Author(s)
  油座　築，永橋　昌幸，市川　寛，島田　能史，若井　俊文
- Organizer
  第5回新潟大学医学系基礎-臨床研究交流会
- Data Source
  KAKENHI-PROJECT-17K10579
[Presentation] Association of activin type II receptor mutation with microsatellite instability in gastric cancer.2017
- Author(s)
  Yuza K，Nagahashi M，Ichikawa H，Nakajima M，Hanyu T，Ishikawa T，Shimada Y，Sakata J，Kameyama H，Kobayashi T，Nakagawa S，Sato N，Honma K，Kawasaki T，Okuda S，Takabe K，Wakai T
- Organizer
  2017 ASCO Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10579
[Presentation] Expression of phosphorylated sphingosine kinase 1 is associated with invasiveness of gastric cancer2017
- Author(s)
  Takaaki Hanyu, Masayuki Nagahashi, Hiroshi Ichikawa, Takashi Ishikawa, Shin-ichi Kosugi, Masato Nakajima, Jun Sakata, Takashi Kobayashi, Hitoshi Kameyama, Toshifumi Wakai
- Organizer
  The 12th Annual Academic Surgical Congress
- Place of Presentation
  Las Vegas（USA）
- Year and Date
  2017-02-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10087
[Presentation] Expression of phosphorylated sphingosine kinase 1 is associated with invasiveness of gastric cancer2017
- Author(s)
  Takaaki Hanyu, Masayuki Nagahashi, Hiroshi Ichikawa, Takashi Ishikawa, Shin-ichi Kosugi, Masato Nakajima, Jun Sakata, Takashi Kobayashi, Hitoshi Kameyama, Toshifumi Wakai
- Organizer
  The 12th Annual Academic Surgical Congress（国際学会）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10087
[Presentation] 膵がんにおけるCRISPR/Cas9を用いたスフィンゴシン-1-リン酸産生酵素の機能解析2017
- Author(s)
  中島　真人，永橋　昌幸，三浦　要平，安藤　拓也，油座　築，土田　純子，田島　陽介，坂田　純，小林　隆，亀山　仁史，阿部　学，崎村　建司，若井　俊文
- Organizer
  第117回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-15H04927
[Presentation] Function Analysis of Sphingosine-1-Phosphate Produced by Sphingosine Kinases in Pancreatic Cancer Progression.2017
- Author(s)
  Masato Nakajima，Masayuki Nagahashi，Junko Tsuchida，Hiroshi Ichikawa，Yoshifumi Shimada，Toshifumi Wakai
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15H04927
[Presentation] High Levels of Ceramide in Breast Cancer and Its Microenvironment.2017
- Author(s)
  Moro K, Tsuchida J, Ohtani A, Endo M, Niwano T, Tatsuda K, Toshikawa C, Hasegawa M, Ikarashi M, Nakajima M, Y. Koyama Y, Sakata J, Kobayashi T, Kameyama H, Takabe K, Wakai T, Nagahashi M
- Organizer
  The 12th Annual Academic Surgical Congress
- Place of Presentation
  Las Vegas, USA
- Year and Date
  2017-02-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05676
[Presentation] 乳がんのがん細胞と宿主におけるスフィンゴシン-1-リン酸産生酵素の機能解析2017
- Author(s)
  中島　真人，永橋　昌幸，大谷　彩香，遠藤　麻已子，土田　純子，諸　和樹，庭野　稔之，山浦　久美子，利川　千絵，長谷川　美樹，五十嵐　麻由子，小山　諭，坂田　純，亀山　仁史，小林　隆，若井　俊文
- Organizer
  第25回日本乳癌学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10538
[Presentation] 膵癌細胞におけるスフィンゴシン-1-リン酸産生酵素の働きとその代謝動態制御の解析2017
- Author(s)
  中島　真人，永橋　昌幸，三浦　要平，安藤　拓也，油座　築，土田　純子，田島　陽介，坂田　純，小林　隆，亀山　仁史，阿部　学，﨑村　建司，曽我　朋義，若井　俊文
- Organizer
  日本外科代謝栄養学会第54回学術集会
- Data Source
  KAKENHI-PROJECT-15H04927
[Presentation] Immune-modulator FTY720 potentiate Doxorubicin in obesity-related breast cancer.2017
- Author(s)
  Takabe K, Katsuta E, Nagahashi M
- Organizer
  The 12th Annual Academic Surgical Congress
- Place of Presentation
  Las Vegas, USA
- Year and Date
  2017-02-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05676
[Presentation] Sphingosine-1-phosphate affects tumor-associated immune cells in human breast cancer patients2017
- Author(s)
  Tsuchida J, Nagahashi M, Moro K, Otani A, Endo M, Ikarashi M, Nakajima M, Koyama Y, Sakata J, Kobayashi T, Kameyama H, Yan Q, Yan L, Takabe K, Wakai T
- Organizer
  The 13th Annual Academic Surgical Congress
- Data Source
  KAKENHI-PROJECT-17K10538
[Presentation] Sphingosine Kinase 1 Contributes to Breast Cancer Cell Metabolism and Survival.2017
- Author(s)
  Nagahashi M, Nakajima M, Saito T, Komatsu M, Soga T, Zhao R, Zhou H, Okuda S, Takabe K, Wakai T
- Organizer
  The 12th Annual Academic Surgical Congress
- Place of Presentation
  Las Vegas, USA
- Year and Date
  2017-02-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15471
[Presentation] 乳癌細胞の代謝動態におけるスフィンゴシン-1-リン酸産生酵素の働き2017
- Author(s)
  永橋昌幸，中島真人，土田純子，諸　和樹，遠藤麻巳子，大渓彩香，庭野稔之，辰田久美子，長谷川美樹，利川千絵，五十嵐麻由子，坂田　純，亀山仁史，小林　隆，高部和明，斎藤哲也，小松雅明，曽我朋義，小山　諭，若井俊文
- Organizer
  第24回外科侵襲とサイトカイン研究会
- Data Source
  KAKENHI-PROJECT-17K10538
[Presentation] 乳癌細胞の代謝動態におけるスフィンゴシン-1-リン酸産生酵素の働き2017
- Author(s)
  永橋昌幸，中島真人，土田純子，諸　和樹，遠藤麻巳子，大渓彩香，庭野稔之，辰田久美子，長谷川美樹，利川千絵，五十嵐麻由子，坂田　純，亀山仁史，小林　隆，高部和明，斎藤哲也，小松雅明，曽我朋義，小山　諭，若井俊文
- Organizer
  第24回外科侵襲とサイトカイン研究会
- Data Source
  KAKENHI-PROJECT-15K15471
[Presentation] Sphingosine-1-phosphate in the Lymphatic Fluid Determined by Novel Methods2017
- Author(s)
  Nagahashi M, Yamada A, Aoyagi T, Allegood J, Wakai T, Spiegel S, Takabe K
- Organizer
  The 12th Annual Academic Surgical Congress
- Place of Presentation
  Las Vegas, USA
- Year and Date
  2017-02-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05676
[Presentation] 胃癌におけるマイクロサテライト不安定性とアクチビン受容体遺伝子変異の検討2017
- Author(s)
  油座　築，永橋　昌幸，市川　寛，羽入　隆晃，石川　卓，中島　真人，島田　能史，坂田　純，亀山　仁史，小林　隆，中川　悟，井筒　浩，兒玉　啓輔，高部　和明，若井　俊文
- Organizer
  第117回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-17K10579
[Presentation] Obesity-induced Sphingosine-1-phosphate in Breast Cancer Interstitial Fluid Promotes Angiogenesis.2017
- Author(s)
  Tsuchida J, Nakajima M, Moro K, Ohtani A, Endo M, Niwano T, Tatsuda K, Toshikawa C, Hasegawa M, Ikarashi M, Koyama Y, Sakata J, Kobayashi T, Kameyama H, Wakai T, Takabe K, Nagahashi M
- Organizer
  The 12th Annual Academic Surgical Congress
- Place of Presentation
  Las Vegas, USA
- Year and Date
  2017-02-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15471
[Presentation] Sphingosine-1-phosphate and tumor-associated immune cells in the tumor microenvironment2017
- Author(s)
  Tsuchida　J， Nagahashi M， Nakajima M， Takabe K， Wakai T
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K15471
[Presentation] Targeting the SphK1/S1P/S1PR1 axis that connects obesity, chronic inflammation, and breast cancer metastasis2017
- Author(s)
  Nagahashi M, Yamada A, Aoyagi T, Huang WC, Terracina KP, Hait N, Allegood JC, Tsuchida J, Nakajima M, Katsuta E, Milstien S, Wakai T, Spiegel S, Takabe K
- Organizer
  2017 San Antonio Breast Cancer Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05676
[Presentation] Roles of Sphingosine-1-Phosphate Produced by Sphingosine Kinases in Pancreatic Cancer Progression2017
- Author(s)
  Nakajima M, Miura Y, Ando T, Yuza K, Tsuchida J, Tajima Y, Abe M, Sakimura K, Wakai T, Nagahashi M
- Organizer
  The 12th Annual Academic Surgical Congress
- Place of Presentation
  Las Vegas, USA
- Year and Date
  2017-02-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15471
[Presentation] Roles of Sphingosine-1-Phosphate Produced by Sphingosine Kinases in Pancreatic Cancer Progression2017
- Author(s)
  Nakajima M, Miura Y, Ando T, Yuza K, Tsuchida J, Tajima Y, Abe M, Sakimura K, Wakai T, Nagahashi M
- Organizer
  The 12th Annual Academic Surgical Congress
- Place of Presentation
  Las Vegas, USA
- Year and Date
  2017-02-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15610
[Presentation] Expression of phosphorylated sphingosine kinase 1 is associated with invasiveness of human gastric cancer2017
- Author(s)
  Takaaki Hanyu, Masayuki Nagahashi, Hiroshi Ichikawa, Takashi Ishikawa, Shin-ichi Kosugi, Masato Nakajima, Jun Sakata, Takashi Kobayashi, Hitoshi Kameyama, Toshifumi Wakai
- Organizer
  第89回日本胃癌学会総会
- Data Source
  KAKENHI-PROJECT-15K10087
[Presentation] Validity of adding intravenous carnitine to parenteral nutrition with lipid emulsion for deceasing inflammatory reaction of postoperative surgical patients.2017
- Author(s)
  Koyama Y, Moro K, Miura K, Nagahashi M, Kosugi S-I, Tsuchida J, Ikarashi M, Nakajima M, Ichikawa H, Shimada Y, Kameyama H, Kobayashi T, Wakai T
- Organizer
  39th ESPEN
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10047
[Presentation] Activin type II receptor as an affordable surrogate to identify microsatellite instability2017
- Author(s)
  Yuza K，Nagahashi M，Ichikawa H，Hanyu T，Ishikawa T，Shimada Y，Sakata J，Kameyama H，Kobayashi T，Izutsu H，Kodama K，Takabe K，Wakai T
- Organizer
  12th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10579
[Presentation] シンポジウム15 私たちが日本で行うべき乳癌研究　基礎から臨床まで日本だからこそできるトランスレーショナルリサーチの実践を目指して2017
- Author(s)
  永橋　昌幸，大渓　彩香，遠藤　麻巳子，土田　純子，諸　和樹，庭野　稔之，辰田　久美子，利川　千絵，長谷川　美樹，五十嵐　麻由子，中島　真人，小山　諭，高部　和明，若井　俊文
- Organizer
  第25回日本乳癌学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10538
[Presentation] Peri-tumor Sphingosine-1-phosphate Levels Are Affected by the Tumor.2017
- Author(s)
  Tsuchida J, Moro K, Ohtani A, Endo M, Niwano T, Tatsuda K, Toshikawa C, Hasegawa M, Ikarashi M, Nakajima M, Y. Koyama1, Sakata J, Kobayashi T, Kameyama H, Takabe K, Wakai T, Nagahashi M
- Organizer
  The 12th Annual Academic Surgical Congress
- Place of Presentation
  Las Vegas, USA
- Year and Date
  2017-02-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05676
[Presentation] Symposia S1：New trends for studying cancer invasion and metastasis The role of sphingosine-1-phosphate in tumor microenvironment and metastasis2017
- Author(s)
  Nagahashi M, Tsuchida J, Nakajima M, Takabe K, Wakai T
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15610
[Presentation] 乳がんのがん細胞と宿主におけるスフィンゴシン-1-リン酸産生酵素の機能解析2017
- Author(s)
  中島真人，永橋昌幸，大谷彩香，遠藤麻已子，土田純子，諸　和樹，庭野稔之，山浦久美子，利川千絵，長谷川美樹，五十嵐麻由子，小山　諭，坂田　純，亀山仁史，小林　隆，若井俊文
- Organizer
  第25回日本乳癌学会学術集会
- Data Source
  KAKENHI-PROJECT-15H05676
[Presentation] Association between Activin receptor type 2A mutation and microsatellite instability in gastric cancer2017
- Author(s)
  Yuza K，Nagahashi M，Ichikawa H，Shimada Y，Nakajima M，Takabe K，Wakai T
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10579
[Presentation] Sphingosine-1-phosphate in the Lymphatic Fluid Determined by Novel Methods2017
- Author(s)
  Nagahashi M, Yamada A, Aoyagi T, Allegood J, Wakai T, Spiegel S, Takabe K
- Organizer
  The 12th Annual Academic Surgical Congress
- Place of Presentation
  Las Vegas, USA
- Year and Date
  2017-02-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15610
[Presentation] Symposia S1：New trends for studying cancer invasion and metastasis The role of sphingosine-1-phosphate in tumor microenvironment and metastasis2017
- Author(s)
  Nagahashi M, Tsuchida J, Nakajima M, Takabe K, Wakai T
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05676
[Presentation] 周術期末梢静脈栄養　脂肪乳剤投与におけるカルニチン併用による炎症反応の軽減効果.2017
- Author(s)
  諸　和樹, 小山　諭, 永橋　昌幸, 三浦　宏平, 土田　純子, 中島　真人, 若井　俊文.
- Organizer
  第54回日本外科代謝栄養学会
- Data Source
  KAKENHI-PROJECT-15K10047
[Presentation] 乳癌および周囲微小環境では高濃度のセラミドが産生される2017
- Author(s)
  諸　和樹，永橋昌幸，遠藤麻巳子，大溪彩香，土田純子，庭野稔之，辰田久美子，長谷川美樹，利川千絵，五十嵐麻由子，中島真人，小山　諭，坂田　純，亀山仁史，小林　隆，高部和明，若井俊文
- Organizer
  第117回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-15K15471
[Presentation] 周術期末梢静脈栄養：脂肪乳剤投与におけるカルニチン併用による炎症反応の軽減効果2017
- Author(s)
  諸　和樹、小山　諭、永橋昌幸、三浦宏平、土田純子、中島真人、若井俊文１
- Organizer
  第5４回日本外科代謝栄養学会
- Place of Presentation
  朱鷺メッセ新潟コンベンションセンター（新潟県新潟市）
- Year and Date
  2017-07-06
- Data Source
  KAKENHI-PROJECT-15K10047
[Presentation] シンポジウム15 私たちが日本で行うべき乳癌研究　基礎から臨床まで日本だからこそできるトランスレーショナルリサーチの実践を目指して2017
- Author(s)
  永橋昌幸，大渓彩香，遠藤麻巳子，土田純子，諸和樹，庭野稔之，辰田久美子，利川千絵，長谷川美樹，五十嵐麻由子，中島真人，小山　諭，高部和明，若井俊文
- Organizer
  第25回日本乳癌学会学術集会
- Data Source
  KAKENHI-PROJECT-15H05676
[Presentation] Expression of Phosphorylated Sphingosine Kinase 1 Is Associated with Invasiveness of Gastric Cancer.2017
- Author(s)
  Hanyu T, Ichikawa H, Ishikawa T, Kosugi S, Nakajima M, Sakata J, Kobayashi T, Kameyama H, Wakai T, Nagahashi M
- Organizer
  The 12th Annual Academic Surgical Congress
- Place of Presentation
  Las Vegas, USA
- Year and Date
  2017-02-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15471
[Presentation] CRISPR/Cas9によるスフィンゴシン-1-リン酸産生酵素の乳癌発育進展における役割解明2017
- Author(s)
  三浦要平，中島真人，永橋昌幸，安藤拓也，油座　築，土田純子，田島陽介，坂田　純，小林　隆，亀山仁史，阿部　学，﨑村建司，若井俊文
- Organizer
  第117回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-15H05676
[Presentation] 肥満を伴う乳癌患者における血清スフィンゴシン-1-リン酸の定量2016
- Author(s)
  土田　純子、永橋　昌幸、遠藤　麻巳子、大溪　彩香、庭野　稔之、辰田　久美子、利川　千絵、長谷川　美樹、五十嵐　麻由子、小山　諭、高部　和明、若井　俊文
- Organizer
  第78回臨床外科学会総会
- Place of Presentation
  グランドプリンスホテル新高輪（東京都港区）
- Year and Date
  2016-11-24
- Data Source
  KAKENHI-PROJECT-15K15471
[Presentation] Serum sphingosine-1-phosphate levels are elevated in breast cancer patients with lymph node metastasis2016
- Author(s)
  Junko Tsuchida, Masayuki Nagahashi, Kazuki Moro, Toshiyuki Niwano, Kumiko Tatsuda, Chie Toshikawa, Miki Hasegawa, Yu Koyama, Takashi Kobayashi, Shin-ichi Kosugi, Hitoshi Kameyama, Hiroaki Aoki, Kazuaki Takabe, Toshifumi Wakai
- Organizer
  The 11th Annual Academic Surgical Congress
- Place of Presentation
  Jacksonville, USA
- Year and Date
  2016-02-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15471
[Presentation] 周術期末梢静脈栄養における脂肪乳剤とカルニチン投与の検討2016
- Author(s)
  小山　諭、諸　和樹、永橋昌幸、三浦宏平、辰田久美子、土田純子、中島真人、若井俊文
- Organizer
  第53回日本外科代謝栄養学会
- Place of Presentation
  伊藤国際学術研究センター(東京都文京区）
- Year and Date
  2016-07-07
- Data Source
  KAKENHI-PROJECT-15K10047
[Presentation] 肥満を伴う乳癌患者における血清スフィンゴシン-1-リン酸の定量2016
- Author(s)
  土田純子, 永橋昌幸, 遠藤麻巳子, 大溪彩香, 庭野稔之, 辰田久美子, 利川千絵, 長谷川美樹, 五十嵐麻由子, 中島真人, 小山諭, 高部和明, 若井俊文
- Organizer
  第78回　日本臨床外科学会総会
- Place of Presentation
  グランドプリンスホテル新高輪（東京都港区）
- Year and Date
  2016-11-24
- Data Source
  KAKENHI-PROJECT-15H04927
[Presentation] Dysregulation of Sphingolipids in Human Breast Cancer2016
- Author(s)
  Masayuki Nagahashi, Junko Tsuchida, Kazuki Moro, Toshiyuki Niwano, Kumiko Tatsuda, Chie Toshikawa, Miki Hasegawa, Yu Koyama, Takashi Kobayashi, Shin-ichi Kosugi, Hitoshi Kameyama, Hiroaki Aoki, Kazuaki Takabe, Toshifumi Wakai
- Organizer
  The 11th Annual Academic Surgical Congress
- Place of Presentation
  Jacksonville, USA
- Year and Date
  2016-02-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15471
[Presentation] Very Long Acyl Chain (C24:0 and C22:0) Ceramides are Associated with Obesity and Breast Cancer Progression2016
- Author(s)
  Kazuki Moro, Masayuki Nagahashi, Junko Tsuchida, Toshiyuki Niwano, Kumiko Tatsuda, Chie Toshikawa, Miki Hasegawa, Yu Koyama, Takashi Kobayashi, Shin-ichi Kosugi, Hitoshi Kameyama, Hiroaki Aoki, Kazuaki Takabe, Toshifumi Wakai
- Organizer
  The 11th Annual Academic Surgical Congress
- Place of Presentation
  Jacksonville, USA
- Year and Date
  2016-02-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05676
[Presentation] 大腸癌化学療法におけるNQO1発現解析の意義2016
- Author(s)
  亀山仁史，廣瀬雄己，島田能史，八木亮磨，田島陽介，岡村拓磨，中野雅人，市川　寛，永橋昌幸，坂田　純，小林　隆，若井俊文
- Organizer
  JDDW 2016
- Place of Presentation
  神戸コンベンションセンター（兵庫県神戸市）
- Year and Date
  2016-11-05
- Data Source
  KAKENHI-PROJECT-26462006
[Presentation] スフィンゴシンキナーゼ欠損細胞の開発とその機能解析2016
- Author(s)
  中島真人, 永橋昌幸, 土田純子, 市川寛, 島田能史, 若井俊文
- Organizer
  第75回　日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15H04927
[Presentation] Clinical significance of NQO1 expression in patients with KRAS wild-type unresectable colorectal cancer2016
- Author(s)
  Hitoshi Kameyama, Yuki Hirose, Yoshifumi Shimada, Ryoma Yagi, Yosuke Tajima, Takuma Okamura, Mae Nakano, Masato Nakano, Masayuki Nagahashi, Takashi Kobayashi, Toshifumi Wakai
- Organizer
  IASGO 2016
- Place of Presentation
  Seoul (South Korea)
- Year and Date
  2016-09-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462006
[Presentation] 乳がん患者における腫瘍内スフィンゴシン-1-リン酸濃度と臨床病理学的因子の関連について2016
- Author(s)
  土田　純子、永橋　昌幸、遠藤　麻巳子、大溪　彩香、庭野　稔之、辰田　久美子、利川　千絵、長谷川　美樹、五十嵐　麻由子、中島　真人、小山　諭、高部　和明、若井　俊文
- Organizer
  第24回日本乳癌学会学術総会
- Place of Presentation
  東京ビックサイト（東京都江東区）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-15H05676
[Presentation] スフィンゴシンキナーゼ欠損細胞の開発とその機能解析2016
- Author(s)
  中島真人, 永橋昌幸, 土田純子, 市川寛, 島田能史, 若井俊文
- Organizer
  第75回　日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K15610
[Presentation] Targeting sphingosine-1-phosphate in obesity-induced angiogenesis in breast cancer progression2016
- Author(s)
  Masayuki Nagahashi, Kazuki Moro, Junko Tsuchida, Toshiyuki Niwano, Kumiko Tatsuda, Chie Toshikawa, Miki Hasegawa, Yu Koyama, Takashi Kobayashi, Shin-ichi Kosugi, Hitoshi Kameyama, Akimitsu Yamada, Tomoyoshi Aoyagi, Kazuaki Takabe, Toshifumi Wakai
- Organizer
  The 11th Annual Academic Surgical Congress
- Place of Presentation
  Jacksonville, USA
- Year and Date
  2016-02-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05676
[Presentation] 肥満によって促進される乳癌の血管新生に対する抗スフィンゴシン-1-リン酸受容体治療2016
- Author(s)
  永橋　昌幸，大渓　彩香，遠藤　麻巳子，土田　純子，諸　和樹，庭野　稔之，辰田　久美子，利川　千絵，長谷川　美樹，五十嵐　麻由子，中島　真人，小山　諭，山田　顕光，青柳　智義，高部　和明，若井　俊文
- Organizer
  第24回日本乳癌学会学術総会
- Place of Presentation
  東京ビックサイト（東京都江東区）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-15K15471
[Presentation] Roles of sphingosine-1-phosphate produced by sphingosine kinases in cancer progression2016
- Author(s)
  Masato Nakajima, Masayuki Nagahashi, Junko Tsuchida, Toshifumi Wakai
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Data Source
  KAKENHI-PROJECT-15H05676
[Presentation] 乳がん手術検体におけるスフィンゴリン脂質の定量2016
- Author(s)
  中島　真人，永橋　昌幸，大渓　彩香，遠藤　麻巳子，土田　純子，諸　和樹，庭野　稔之，辰田　久美子，利川　千絵，長谷川　美樹，五十嵐　麻由子，小山　諭，若井　俊文
- Organizer
  第24回日本乳癌学会学術総会
- Place of Presentation
  東京ビックサイト（東京都江東区）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-15K15471
[Presentation] 検診発見および自己発見乳癌の臨床病理学的特徴と長期成績2016
- Author(s)
  土田純子, 永橋昌幸, 諸和樹, 庭野稔之, 辰田久美子, 利川千絵, 長谷川美樹, 萬羽尚子, 五十嵐麻由子, 小山諭, 市川寛, 中島真人, 島田能史, 坂田純, 小林隆, 亀山仁史, 若井俊文
- Organizer
  第116回　日本外科学会定期学術集会
- Place of Presentation
  大阪国際会議場（大阪府大阪市北区）
- Year and Date
  2016-04-14
- Data Source
  KAKENHI-PROJECT-15H04927
[Presentation] 胆汁酸はスフィンゴシン-1-リン酸シグナル伝達系を介して肝臓における脂質代謝を調節している2015
- Author(s)
  永橋　昌幸，廣瀬　雄己，須藤　翔，大橋　拓，滝沢　一泰，高野　可赴，坂田　純，小林　隆，若井　俊文
- Organizer
  第51日本胆道学会学術集会
- Place of Presentation
  ホテル東日本宇都宮（栃木県宇都宮市）
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-15H04927
[Presentation] Obesity increases the lipid mediator, sphingosine-1-phosphate in the tumor and tumor microenvironment, and promotes tumor progression2015
- Author(s)
  Junko Tsuchida, Masayuki Nagahashi, Kazuki Moro, Kumiko Tatsuda, Yu Koyama, Kazuaki Takabe, Toshifumi Wakai
- Organizer
  San Antonio Breast Cancer Symposium 2015
- Place of Presentation
  San Antonio, USA
- Year and Date
  2015-12-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15471
[Presentation] 肥満はスフィンゴシン-1-リン酸を癌微小環境において増加させる2015
- Author(s)
  永橋　昌幸，諸　和樹，土田　純子，辰田　久美子，利川　千絵，長谷川　美樹，萬羽　尚子，五十嵐　真由子，坂田　純，小林　隆，亀山　仁史，皆川　昌広，小杉　伸一，小山　諭，高部　和明，若井　俊文
- Organizer
  第115回日本外科学会定期学術集会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-04-16
- Data Source
  KAKENHI-PROJECT-15H04927
[Presentation] がん微小環境中にはスフィンゴシン -1-リン酸（S1P）が高濃度で存在する2015
- Author(s)
  永橋　昌幸，土田　純子，諸　和樹，辰田　久美子，利川　千絵，長谷川　美樹，萬羽　尚子，五十嵐　麻由子，小山　諭，山田　顕光，青柳　智義，高部　和明，若井　俊文
- Organizer
  第23回日本乳癌学会学術集会
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Year and Date
  2015-07-02
- Data Source
  KAKENHI-PROJECT-15H05676
[Presentation] FTY720 decreases levels of lipid mediator in tumor microenvironment and suppresses breast cancer progression2015
- Author(s)
  Masayuki Nagahashi, Kazuki Moro, Junko Tsuchida, Kumiko Tatsuda, Jun Sakata, Takashi Kobayashi, Kazuaki Takabe, Toshifumi Wakai
- Organizer
  46th World Congress of Surgery
- Place of Presentation
  Bangkok, Thailand
- Year and Date
  2015-08-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05676
[Presentation] A lipid mediator, sphingosine-1-phosphate as a　promising target　for colitis-associated cancer2015
- Author(s)
  Masayuki Nagahashi, Yoshifumi Shimada, Jun Sakata, Hitoshi Kameyama, Takashi Kobayashi, Kazuaki Takabe, Yasuo Saijo, Toshifumi Wakai
- Organizer
  第13回日本臨床腫瘍学会学術集会
- Place of Presentation
  ロイトン札幌（北海道札幌市）
- Year and Date
  2015-07-16
- Data Source
  KAKENHI-PROJECT-15H05676
[Presentation] 胆汁酸はスフィンゴシン-1-リン酸シグナル伝達系を介して肝臓における脂質代謝を調節している2015
- Author(s)
  永橋　昌幸，廣瀬　雄己，須藤　翔，大橋　拓，滝沢　一泰，高野　可赴，坂田　純，小林　隆，若井　俊文
- Organizer
  第51日本胆道学会学術集会
- Place of Presentation
  ホテル東日本宇都宮（栃木県宇都宮市）
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-15K15471
[Presentation] Specific inhibitor of a bioactive lipid mediator suppresses breast cancer-induced angiogenesis and lymphangiogenesis2015
- Author(s)
  Masayuki Nagahashi, Kazuki Moro, Junko Tsuchida, Kumiko Tatsuda, Chie Toshikawa, Miki Hasegawa, Yoshifumi Shimada, Kazuaki Takabe, Yasuo Saijo, Toshifumi Wakai
- Organizer
  第13回日本臨床腫瘍学会学術集会
- Place of Presentation
  ロイトン札幌（北海道札幌市）
- Year and Date
  2015-07-16
- Data Source
  KAKENHI-PROJECT-15K15471
[Presentation] IMPACT OF SURGICAL RESECTION AND CHEMOTHERAPY ON LONG-TERM OUTCOMES IN PATIENTS WITH LOCALLY ADVANCED GALLBLADDER CARCINOMA2015
- Author(s)
  T. Wakai, J. Sakata, Y. Hirose, N. Sudo, T. Katada, K. Takizawa, M. Nagahashi, T. Kobayashi
- Organizer
  46th World Congress of Surgery
- Place of Presentation
  Bangkok, Thailand
- Year and Date
  2015-08-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04927
[Presentation] LONG-TERM OUTCOMES OF SURGICAL RESECTION FOR EARLY GALLBLADDER CARCINOMA2015
- Author(s)
  T. Wakai, J. Sakata, Y. Hirose, N. Sudo, T. Katada, K. Takizawa, M. Nagahashi, T. Kobayashi
- Organizer
  46th World Congress of Surgery
- Place of Presentation
  Bangkok, Thailand
- Year and Date
  2015-08-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04927
[Presentation] NQO1 EXPRESSION HAS PROGNOSTIC SIGNIFICANCE IN KRAS-WILD UNRESECTABLE COLORECTAL CANCER
- Author(s)
  Y. Hirose, H. Kameyama, T. Ohashi, K. Takizawa, M. Nagahashi, T. Kobayashi, J. Sakata, T. Wakai
- Organizer
  46th World Congress of Surgery
- Place of Presentation
  Bangkok
- Year and Date
  2015-08-23 – 2015-08-27
- Data Source
  KAKENHI-PROJECT-26462006

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nagahashi masayuki 永橋 昌幸

NAGAHASHI Masayuki 永橋 昌幸

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脂質メディエーター分子機構の癌特異的阻害による乳癌新治療の実現へ向けた前臨床研究Principal Investigator

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乳癌における脂質メディエーターを標的とする薬物送達システムを用いた新規治療の開発Principal Investigator

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トリプルネガティブ乳癌におけるTP53と脂質分子の相補的な細胞制御機構の解明Principal Investigator

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nagahashi masayuki 永橋昌幸

NAGAHASHI Masayuki 永橋昌幸