mori wakana 森若菜

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Mori Wakana 森若菜

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Researcher Number	30835442
Affiliation (Current)	2025: 国立研究開発法人量子科学技術研究開発機構, 量子医科学研究所先進核医学基盤研究部, 研究員
Affiliation (based on the past Project Information) *help	2021 – 2024: 国立研究開発法人量子科学技術研究開発機構, 量子医科学研究所先進核医学基盤研究部, 研究員 2022: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所先進核医学基盤研究部, 研究員(任常) 2021: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所先進核医学基盤研究部, 研究員 2019 – 2020: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所先進核医学基盤研究部, 研究員(任常)
Review Section/Research Field	Principal Investigator Basic Section 52040:Radiological sciences-related Except Principal Investigator Basic Section 52040:Radiological sciences-related
Keywords	Principal Investigator PETプローブ / LRRK2 / パーキンソン病 / LRRK２ Except Principal Investigator 11C / AMPA受容体 / PET / GluA2 / GluA1 / AMPA受容体調節性タンパク … More / PETプローブ / PETイメージング / 環状ヌクレオチドホスホジエステラーゼ7 / mGluR1 / グルタミン酸 / URB597 / TARP-g8 / 結合能 / BPND / AMPA受容体調節タンパク / エンドカンナビノイド / Binding potential / AMPA受容体調節性タンパクγ―8 / MAGL / FAAH / TARP / AMPA Less

パーキンソン病の病態解明に資する変異型LRRK2をターゲットとしたPETプローブの開発Principal Investigator
- Principal Investigator
  
  森若菜
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Institutes for Quantum Science and Technology
Development of PET probes for cyclic nucleotide phosphodiesterases 7
- Principal Investigator
  
  張明栄
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Institutes for Quantum Science and Technology
PET study for AMPA-TARPg8 complex in epilepsy.
- Principal Investigator
  
  山崎友照
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Institutes for Quantum Science and Technology
Development of a PET probe targeting mutant LRRK2 to elucidate the pathogenesis of Parkinson's disease.Principal Investigator
- Principal Investigator
  
  Mori Wakana
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Institutes for Quantum Science and Technology
PET study for molecular interactions in glutamate excitotoxicity
- Principal Investigator
  
  Yamasaki Tomoteru
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Institutes for Quantum Science and Technology

All 2024 2023 2020 2019

All Journal Article Presentation

[Journal Article] Preclinical Evaluation of Novel Positron Emission Tomography (PET) Probes for Imaging Leucine-Rich Repeat Kinase 2 (LRRK2)2024
- Author(s)
  Chen Zhen、Chen Jiahui、Mori Wakana、Yi Yongjia、Rong Jian、Li Yinlong、Leon Erick R. Calderon、Shao Tuo、Song Zhendong、Yamasaki Tomoteru、Ishii Hideki、Zhang Yiding、Kokufuta Tomomi、Hu Kuan、Xie Lin、Josephson Lee、Van Richard、Shao Yihan、Factor Stewart、Zhang Ming-Rong、Liang Steven H.
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 67 Issue: 4 Pages: 2559-2569
- DOI
  10.1021/acs.jmedchem.3c01687
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07659, KAKENHI-PROJECT-23K27558
[Journal Article] Automated radiosynthesis and in vivo evaluation of 18F-labeled analog of the photosensitizer ADPM06 for planning photodynamic therapy2023
- Author(s)
  Kawamura Kazunori、Yamasaki Tomoteru、Fujinaga Masayuki、Kokufuta Tomomi、Zhang Yiding、Mori Wakana、Kurihara Yusuke、Ogawa Masanao、Tsukagoe Kaito、Nengaki Nobuki、Zhang Ming-Rong
- Journal Title
  
  EJNMMI Radiopharmacy and Chemistry
  
  Volume: 8 Issue: 1 Pages: 1-12
- DOI
  10.1186/s41181-023-00199-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K27558
[Journal Article] Development of Novel 11C-Labeled Selective Orexin-2 Receptor Radioligands for Positron Emission Tomography Imaging2023
- Author(s)
  Rong Jian、Yamasaki Tomoteru、Li Yinlong、Kumata Katsushi、Zhao Chunyu、Haider Ahmed、Chen Jiahui、Xiao Zhiwei、Fujinaga Masayuki、Hu Kuan、Mori Wakana、Zhang Yiding、Xie Lin、Zhou Xin、Collier Thomas L.、Zhang Ming-Rong、Liang Steven
- Journal Title
  
  ACS Medicinal Chemistry Letters
  
  Volume: 14 Issue: 10 Pages: 1419-1426
- DOI
  10.1021/acsmedchemlett.3c00320
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07659, KAKENHI-PROJECT-23K27558
[Journal Article] Development of an In Vivo Method to Estimate Effective Drug Doses and Quantify Fatty Acid Amide Hydrolase in Rodent Brain using Positron Emission Tomography Tracer N-(3,4-dimethylisoxazol-5-yl)piperazine-4-[4-(2-fluoro-4-[11C]methylphenyl)thiazol-2-yl]-1-carboxamide ([11C]DFMC)2020
- Author(s)
  Yamasaki Tomoteru、Ohya Tomoyuki、Mori Wakana、Zhang Yiding、Wakizaka Hidekatsu、Nengaki Nobuki、Fujinaga Masayuki、Kikuchi Tatsuya、Zhang Ming-Rong
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics
  
  Volume: - Issue: 3 Pages: 353-360
- DOI
  10.1124/jpet.119.263772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08240, KAKENHI-PROJECT-20H03635
[Presentation] Radiosynthesis and evaluation of a new PET tracer for imaging of leucine-rich repeat kinase 2.2023
- Author(s)
  森若菜、念垣　信樹、山崎友照、熊田勝志、藤永雅之、張明栄
- Organizer
  ISRS2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07632
[Presentation] Radiosynthesis and evaluation of a new PET tracer for imaging of leucine-rich repeat kinase 2.2023
- Author(s)
  Wakana Mori, Nobuki Nengaki, Tomoteru Yamasaki, Katsushi Kumata, Masayuki Fujinaga, Ming-Rong Zhang
- Organizer
  25th iSRS, Society of Radiopharmaceutical Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27558
[Presentation] LRRK2をターゲットとする新規PETプローブの合成及び動物評価2023
- Author(s)
  森若菜、念垣　信樹、山崎友照、藤永雅之、張明栄
- Organizer
  第63回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07632
[Presentation] モノアシルグリセロールリパーゼを標的としたPETプローブを用いた脳内pHイメージング法の開発2020
- Author(s)
  山崎　友照、平石　惇人、森　若菜、大久保　崇之、栗原　雄祐、念垣　信樹、張　明栄
- Organizer
  第60回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08240
[Presentation] Small-animal PET study: excess glutamate release upregulates mGluR1 availability2019
- Author(s)
  山崎　友照、岡田　真希、森　若菜、張　一鼎、脇坂　秀克、小川　政直、藤永　雅之、張　明栄
- Organizer
  第59回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08240

1. Yamasaki Tomoteru (80627563)

# of Collaborated Projects: 5 results

# of Collaborated Products: 7 results
2. 藤永雅之 (70623726)

# of Collaborated Projects: 5 results

# of Collaborated Products: 7 results
3. 張明栄 (80443076)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. 謝琳 (30623558)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 石井英樹 (80425610)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 胡寛

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

mori wakana 森 若菜

Mori Wakana 森 若菜

Research Projects

Research Products

Co-Researchers

パーキンソン病の病態解明に資する変異型LRRK2をターゲットとしたPETプローブの開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of PET probes for cyclic nucleotide phosphodiesterases 7

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

PET study for AMPA-TARPg8 complex in epilepsy.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a PET probe targeting mutant LRRK2 to elucidate the pathogenesis of Parkinson's disease.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

PET study for molecular interactions in glutamate excitotoxicity

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Preclinical Evaluation of Novel Positron Emission Tomography (PET) Probes for Imaging Leucine-Rich Repeat Kinase 2 (LRRK2)2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Automated radiosynthesis and in vivo evaluation of 18F-labeled analog of the photosensitizer ADPM06 for planning photodynamic therapy2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of Novel 11C-Labeled Selective Orexin-2 Receptor Radioligands for Positron Emission Tomography Imaging2023

Author(s)

Journal Title

DOI

Data Source

Author(s)

Journal Title

DOI

Data Source

[Presentation] Radiosynthesis and evaluation of a new PET tracer for imaging of leucine-rich repeat kinase 2.2023

Author(s)

Organizer

Data Source

[Presentation] Radiosynthesis and evaluation of a new PET tracer for imaging of leucine-rich repeat kinase 2.2023

Author(s)

Organizer

Data Source

[Presentation] LRRK2をターゲットとする新規PETプローブの合成及び動物評価2023

Author(s)

Organizer

Data Source

[Presentation] モノアシルグリセロールリパーゼを標的としたPETプローブを用いた脳内pHイメージング法の開発2020

Author(s)

Organizer

Data Source

[Presentation] Small-animal PET study: excess glutamate release upregulates mGluR1 availability2019

Author(s)

Organizer

Data Source

mori wakana 森若菜

Mori Wakana 森若菜