MIWA Shiro 三輪史朗

… Alternative Names

三輪史郎ミワシロウ

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Researcher Number	40034954
Affiliation (based on the past Project Information) *help	2002 – 2004: (財)冲中記念成人病研究所, 理事長(研究職) 2000 – 2001: (財)沖中記念成人病研究所, 顧問研究員 2000: Okinaka Memorial Institute for Medical Research, Professor Emeritus, 顧問研究員 1999: 財団法人冲中記念成人病研究所, 所長 1999: Okinaka memorial institute for medical research, Director, 所長 … More 1998: 冲中記念成人病研究所, 所長 1998: 沖中記念成人病研究所, 所長(研究職) 1998: 財)冲中記念成人病研究所, 所長 1998: Okinaka Memorial Inst.Med.Res.Director, 所長 1992 – 1997: (財)冲中記念成人病研究所, 所長 1996: 財団法人冲中記念成人病研究所, 所長 1994: (財)沖中記念成人病研究所, 所長 1992: 冲中記念成人病研究所, 所長 1990 – 1991: (財)沖中記念成人病研究所, 所長 1989: 沖中記念成人病研究所, 所長 1988 – 1989: (財)冲中記念成人病研究所, 所長 1988: (財)冲中記念成人研究所, 所長 1988: (財)沖中記念成人病研究所, 副所長 1987: ス沖中記念成人病研究所, 所長 1986 – 1987: 東京大学, 医科学研究所病態薬理学, 教授 1986: 東京大学, 医科学研究所, 教授 1986: Professor, Institute of Medical Science, University of Tokyo, 医科学研究所, 教授 1985: 東京大学, 医科研, 教授 Less
Review Section/Research Field	Principal Investigator Hematology Except Principal Investigator Human genetics / Hematology / Pathological medical chemistry / Biological Sciences / Molecular biology
Keywords	Principal Investigator 赤血球酵素異常症 / pyruvate kinase deficiency / erythroenzymopathies / hereditary hemolytic anemia / ピルビン酸キナーゼ異常症 / 赤血球酵素 / サラセミア / triosephosphate isomerase / gene / hemolytic anemia … More / pyruvate kinase / red cell enzyme / 染色体 / ピルビン酸キナーゼ欠乏(異常)症 / ピルビン酸キナーゼ / 病因解明 / 転写促進因子 / 単一塩基置換 / 遺伝子解析 / ピルビン酸キナ-ゼ欠乏症 / 三炭糖リン酸イソメラ-ゼ / 遺伝子 / 溶血性貧血 / 遺伝性溶血性貧血 / ピルビン酸キナ-ゼ異常(欠乏)症 / ピルビン酸キナ-ゼ / human L-type PK cDNA / L型PK遺伝子座 / ヒトL型PKcDNAクローン / 遺伝性血性貧血 / 慢性肉芽腫症 / 血友病 / 遺伝性楕円赤血球症 / 不安定ヘモグロビン症 / 遺伝性血液疾患 / 赤血球膜 / 遺伝病 / ピリミジン-5′-ヌクレオチダーゼ欠乏症 / ピルビン酸キナーゼ欠乏症 / 異常ヘモグロビン / 血液疾患 … More Except Principal Investigator 溶血性貧血 / 赤血球酵素異常症 / 変異酵素 / 先天代謝異常 / トランスジェニックマウス / モデルマウス / 解糖系 / 赤血球 / 構造異常 / 遺伝子治療 / Hemolytic anemia / アイソザイム / 遺伝性溶血性貧血 / 分子遺伝学 / 分子生物学 / 遺伝生化学 / 先天性代謝病 / 遺伝子変異 / ピルビン酸キナーゼ / G6PD異常症 / 代謝異常 / hemolytic anemia / G6PD variant / ミスセンス変異 / ピルビン酸キナーゼ異常症 / 細胞特異的発現 / 転写因子 / 機能異常 / 単一アミノ酸置換 / 単一塩基置換 / Diabetes / high blood pressure / circulatory organ / A genome / Allergic asthma / DNAチップ / リュウマチ / 多因子疾患 / 喘息 / アレルギー / 高血圧 / 糖尿病 / 循環器・高血圧 / ゲノム / アレルギー喘息 / Friend cells / disease model animals / reactive oxygen species / glycolysis / apoptosis / フレンド細胞 / 活性酸素種 / アポトーシス / Molecular analysis / Southern Mongoloids / Glucose-6-phosphate dehydrogenase deficiency / G6PD Viangchan / 遺伝子解析 / 南方モンゴロイド / G6PD変異酵素 / Erythroenzymopathies / Transcriptional regulation / Gene therapy / Transgenic mice / Metabolic disorder / Genetic disease / Glycolysis / 遺伝病 / 細胞特量的発現 / 転写調節 / 疾患モデルマウス / Purification / Pyrimidine 5'-nucleotidase deficiency / Isozymes / Pyrimidine 5'-nucleotidase / ピリミジン5'-ヌクレオチダーゼ異常症 / P5N異常症 / ピリミジン5'-ヌクレオチダーゼ / 遺伝子発現。 / グリコースー6-リン酸脱水素酵素異常症 / 骨髄移植 / 重症感染症 / 好中球 / 多能性造血幹細胞 / 顆粒球コロニー刺激因子 / 血中GーCSF値 / 細胞内情報伝達 / 顆粒球コロニー / 造血幹細胞 / 顆粒球コロニー刺激因子(GーCSF) / 先天性代謝異常 / 生命倫理 / 複合疾患 / 生活習慣病 / 人類進化 / ヒト遺伝子多様性 / 融合タンパク / 組み換え型酵素 / グルコースリン酸イソメラーゼ異常症 / エンハンサー / プロモーター / 組織特異的発現 / モレゴロイド / パプアニューギニア / ハプロタイプ / SSCP法 / エリスロポエチン / 疾患モデル / molecular analysis / G6PD deficiency / フレームシフト変異 / スプライシング変異 / 分化誘導 / ホスホグリセリン酸キナーゼ異常症 / ピルビン酸キナ-ゼ異常症 / 遺伝子移入 / グリコ-スー6ーリン酸脱水素酵素異常症 Less

Research Projects
(26 results)
Co-Researchers
(40 People)

Genomic analysis on genetic factors of human diseases and elucidation of their molecular mechanisms
- Principal Investigator
  
  SUGANO Sumio
- Project Period (FY)
  2000 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Physiological significance of pyruvate kinase isozymes in erythrocyte.
- Principal Investigator
  
  KANNO Hitoshi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  NIHON UNIVERSITY
ヒト遺伝子の多様性:その由来と医学・生物学的意義
- Principal Investigator
  
  TOKUNAGA Katsushi
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  The University of Tokyo
Molecular Analysis of Glucose-6-phosphate dehydrogenase variants in southern Mongoloids
- Principal Investigator
  
  HIRONO Akira
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human genetics
- Research Institution
  Okinaka Memorial Institute for Medical Research
Regulation of human pyruvate kinase gene in red cells
- Principal Investigator
  
  KANNO Hitoshi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Okinaka Memorial Institute for Medical Research
赤血球酵素異常症モデルマウスを用いた遺伝子治療の基礎的研究
- Principal Investigator
  
  菅野仁
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Okinaka Memorial Institute for Medical Research
赤血球酵素異常症・発現したタンパクによる変異酵素の機能解析
- Principal Investigator
  
  藤井寿一
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Tokyo Women's Medical University
ピルビン酸キナーゼ異常症モデルマウスにおける遺伝性溶血性貧血の発症機構解明
- Principal Investigator
  
  菅野仁
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Okinaka Memorial Institute for Medical Research
赤血球酵素異常症の病因解明とモデルマウスを用いた新しい治療法の検討
- Principal Investigator
  
  藤井寿一
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Tokyo Women's Medical University
SSCP法によるグルコース-6ーリン酸脱K素酵素異常症遺伝子のハプロタイプ解析
- Principal Investigator
  
  廣野晃
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Human genetics
- Research Institution
  Okinaka Memorial Institute for Medical Research
赤芽球分化に伴う赤血球型ピルビン酸キナーゼの発現とその転写制御
- Principal Investigator
  
  KANNO Hitoshi
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Okinaka Memorial Institute for Medical Research
原因不明の遺伝性非球状性溶血性貧血の遺伝子レベルでの病因解明
- Principal Investigator
  
  藤井寿一
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Tokyo Women's Medical University
迅速PCR-SSCP法によるグルコース-6ーリン酸脱水素.酵素異常症遺伝子の解析
- Principal Investigator
  
  HIRONO Akira
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Human genetics
- Research Institution
  Okinaka Memorial Institute for Medical Research
赤血球酵素異常による遺伝性溶血性貧血の遺伝子レベルでの病因解明
- Principal Investigator
  
  藤井寿一
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Tokyo Women's Medical University
Purification and cDNA cloning of human red cell pyrimidine 5'-nucleotidase isozymes
- Principal Investigator
  
  HIRONO Akira
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Human genetics
- Research Institution
  Okinaka Memorial Institute for medical Research
ピルビン酸キナ-ゼ異常による遺伝性溶血性貧血の病因解明
- Principal Investigator
  
  藤井寿一
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Tokyo Women's Medical University
グルコ-スー6ーリン酸脱水素酵素変異種を指標としたわが国への遺伝子移子移込の検討
- Principal Investigator
  
  FUJII Hisaichi
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Human genetics
- Research Institution
  Tokyo Women's Medical University
ヒト細胞におけるピルビン酸キナーゼアイソザイムの発現機構の解明
- Principal Investigator
  
  藤井寿一
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Human genetics
- Research Institution
  Tokyo Women's Medical University
Erythroenzymopathies: Molecular analysis of pyruvate kinase deficiencyPrincipal Investigator
- Principal Investigator
  
  MIWA Shiro
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Okinaka Memorial Institute for Medical Research
グルコースー6-リン酸脱水素酵素異常症の遺伝子レベルでの病因解析
- Principal Investigator
  
  藤井寿一
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Human genetics
- Research Institution
  Tokyo Women's Medical University
遺伝性血液疾患の病因解析Principal Investigator
- Principal Investigator
  
  三輪史朗
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  The University of Tokyo
ヒト顆粒球コロニー刺激因子(hGーCSF)に関する基礎的臨床的研究
- Principal Investigator
  
  浅野茂隆
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
遺伝性血液疾患の病因解析Principal Investigator
- Principal Investigator
  
  三輪史朗
- Project Period (FY)
  1985
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  The University of Tokyo
先天性代謝病の病因解析と治療に関する研究(総括班)
- Principal Investigator
  
  北川照男
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Nihon University
先天性代謝病の病因解析と治療に関する研究(総括班)
- Principal Investigator
  
  北川照男
- Project Period (FY)
  1985 – 1988
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Nihon University
Erythroenzymopathies: Mechanisms of isozyme switches and clarification of genetic abnormalitiesPrincipal Investigator
- Principal Investigator
  
  MIWA Shiro
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  University of Tokyo

1. FUJII Hisaichi (70107762)

# of Collaborated Projects: 12 results

# of Collaborated Products: 0 results
2. KANNO Hitoshi (70221207)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. HIRONO Akira (90181221)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. TOKUNAGA Katsushi (40163977)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 薮内百治 (20028335)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. KOIZUMI Tsutomu (40126579)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 五條堀孝 (50162136)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 北川照男 (50058765)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 多田啓也 (20046907)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 折居忠夫 (20045339)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 佐伯武頼 (10056070)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. NOGUCHI Tamio (70135721)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. AIZAWA Shin (30202443)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. NAKAGAWA Shigeki (40059465)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. OYAIZU Naoki (00282773)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. SUGANO Sumio (60162848)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. HATA Akira (00244541)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. MIKI Tetsuro (00174003)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. NIIKAWA Norio (00111170)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. MAEDA Tadakazu (90265728)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. MORISAKI Takayuki (30174410)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 菅野晴夫 (10085615)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 榊佳之 (10112327)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 猪子英俊 (10101932)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 八幡義人 (70069011)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 向井常博 (40108741)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 田中武彦 (60028272)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 米山良昌 (10019515)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 宮地隆興 (60034906)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 浅野茂隆 (50134614)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 家城隆次 (60168086)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 幸道秀樹 (80161876)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 長田重一 (70114428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 成富研二 (20101446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 福嶋義光 (70273084)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 林健志 (00019671)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 濱口秀夫 (00091918)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 笹月健彦 (50014121)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. 矢崎義雄 (20101090)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. 白藤尚毅

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MIWA Shiro 三輪 史朗

三輪 史郎 ミワ シロウ

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MIWA Shiro 三輪史朗

三輪史郎ミワシロウ