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KAWANISHI Toru  川西 徹

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… Alternative Names

KAWANISHI Tooru  川西 徹

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Researcher Number 40124383
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2012: 国立衛生試験所, 部長
2011: 国立医薬品食品衛生研究所, 副所長
2009: 国立衛生試験所, 部長
2006 – 2007: 国立医薬品食品衛生研究所, 薬品部, 部長
2004 – 2006: 国立医薬品食品衛生研究所, 生物薬品部, 部長 … More
2002: National Institute of Health Sciences, Head, 所長
2002: 国立医薬品食品衛生研究所, 生物薬品部, 部長
2001: 国立医薬品食品衛生研究所, 生物薬品部, 室長
1997 – 1999: 国立医薬品食品衛生研究所, 生物薬品部, 室長
1995 – 1996: National Institute of Health Sciences, Division of Biological Chemistry and Biologicals, Chief, 生物薬品部, 室長
1994: 国立衛生試験所, 病理部, 室長
1986: Researcher, Section of biochemical Pharmacology, Biological Safety Research Cent, 薬理部, 研究員 Less
Review Section/Research Field
Principal Investigator
General pharmacology / Medical pharmacy
Except Principal Investigator
General pharmacology / Biological pharmacy / Biomedical engineering/Biological material science / General pharmacology
Keywords
Principal Investigator
蛍光プローブ / 共焦点レーザー走査顕微鏡 / カルシウムイオン / FRET / FcRn / カルシウムスパーク / 心筋細胞 / カルシウムウェーブ / 肝細胞 / レーザー顕微鏡 … More / confocal laser scanning microscopy / calcium ion / calcium wave / fluorescent probes / liver / hepatocyte / チロシンリン酸化 / SH2ドメイン / GFP / 蛍光顕微鏡 / SHドメイン / 画像解析 / src-類似領域 / tyrosine phosphorylation / SH2 domain / fluorescence probe / Green Fluorescence Protein / fluorescence microscopy / Fcドメイン / 受容体 / タンパク質性医薬品 / 血中半減期 / タンパク質 / 医薬品 / タンバク質 / 体内動態 / Fc domain / receptor / protein drugs / serum half life … More
Except Principal Investigator
イメージング / Na^+ / Ca^<2+>交換機構 / 肺静脈心筋 / 自動能 / Ca^<2+>チャネル / 心筋 / 虚血再灌流障害 / ナトリウム・カルシウム交換機構 / ミトコンドリア / ナトリウムカルシウム交換機構 / 細胞内カルシウム / 肺動脈心筋 / Na^+/Ca^<2+>交換機構 / 筋小胞体 / T型カルシウムチャネル / 薬理学 / カルシウムイメージング / 心房細動 / カルシウム / 活性酸素 / 酸化ストレス / Gタンパク質 / 7回膜貫通型受容体 / Ca^<2+>シグナル / 心筋細胞 / 心肥大 / G-タンパク質 / システイン / 興奮収縮連関 / カルシウムシグナリング / カルシウムチャネル / リアノジン受容体 / reactive oxygen species / oxidative stress / G protein / seven transmembrane / Ca^<2+> signaling / C^<2+> channel / cardiac myocyte / cardiac hypertrophy / バイオイメージング / ナノプローブ / 蛍光 / 燐光 / 微小循環 / 血流 / 酸素分圧 / Pdポルフィリン / 螢光 / 糖尿病 / Bioimaging / Nano-probes / Fluorescense / Phosphorescence / Microcirculation / Blood flow / Oxygen tension / Pd-porphyrin / 腎臓 / 単離細胞 / 腎毒性 / 実験モデル / Renal cells / Freshly isolated renal cells Less
  • Research Projects

    (10 results)
  • Research Products

    (21 results)
  • Co-Researchers

    (25 People)
  •  Spatio-temporal analysis of intracellularcalcium oscillation in the pulmonary vein myocardium

    • Principal Investigator
      NAMEKATA Iyuki
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General pharmacology
    • Research Institution
      Toho University
  •  The role of intracellular calcium and sodium-calcium exchanger in the automaticity of pulmonary vein myocardium.

    • Principal Investigator
      TANAKA Hikaru
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Toho University
  •  Fluorescence imaging analysis of Na^+/Ca^<2+> exchanger dynamics in myocardial ischemia reperfusion injury

    • Principal Investigator
      NAMEKATA Iyuki
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (Start-up)
    • Research Field
      General pharmacology
    • Research Institution
      Toho University
  •  Studies on molecular basis of the pharmacokinetic regulation of protein drugs consisting of immunoglobulin Fc regionPrincipal Investigator

    • Principal Investigator
      KAWANISHI Toru
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      National Institute of Health Sciences
  •  Development of Photonic-imaging System with Fluorescent and Phosphorescent Nano-probes

    • Principal Investigator
      HINAMITANI Haruyuki
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Keio University
  •  Novel Therapeutic Strategy for Heart Failure : Molecular Mechanism underlying the Regulation of Ca^<2+> Signaling in the Heart

    • Principal Investigator
      NAGAO Taku
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      National Institute of Health Sciences
  •  Development of Real-time Imaging Method of Protein Tyrosine PhosphorylationPrincipal Investigator

    • Principal Investigator
      KAWANISHI Toru
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      National Institute of Health Sciences
  •  細胞内カルシウムスパーク現象の分子メカニズムの研究Principal Investigator

    • Principal Investigator
      川西 徹
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      国立衛生試験所
  •  Study on molecular Mechanism of Calcium Waves Using Rapid Scanning Confocal MicroscopyPrincipal Investigator

    • Principal Investigator
      KAWANISHI Toru
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      National Institute of Health Sciences
  •  Freshly isolated renal cells as a experimental model system for studying the chemically induced renal injury.

    • Principal Investigator
      TAKAHASHI Atsushi
    • Project Period (FY)
      1984 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      National Institute of Hygienic Sciences.

All 2011 2010 2009 2008 2007 2006 2004

All Journal Article Presentation

  • [Journal Article] Involvement of the Na+/Ca2+ exchanger in the automaticity of guinea-pig pulmonary vein myocardium as revealed by SEA0400.2009

    • Author(s)
      Iyuki Namekata, Yayoi Tsuneoka, Akira Takahara, Hideaki Shimada, Takahiko Sugimoto, Kiyoshi Takeda, Midori Nagaharu, Koki Shigenobu, Toru Kawanishi, Hikaru Tanaka
    • Journal Title

      J. Pharmacol. Sci 110(1)

      Pages: 111-116

    • NAID

      10025736868

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20890233
  • [Journal Article] New aspects for the treatment of cardiac diseases based on the diversity of functional controls on cardiac muscles: diversity in the excitation-contraction mechanisms of the heart.2009

    • Author(s)
      Hikaru Tanaka, Iyuki Namekata, Hideaki Nouchi, Koki Shigenobu, Toru Kawanishi, Akira Takahara
    • Journal Title

      J. Pharmacol. Sci 109(3)

      Pages: 327-333

    • NAID

      10025734834

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20890233
  • [Journal Article] New aspects for the treatment of cardiac diseases based on the diversity of functional controls on cardiac muscles : diversity in the excitation-contraction mechanisms of the heart2009

    • Author(s)
      Hikaru Tanaka, Iyuki Namekata, Hideaki Nouchi, Koki Shigenobu, Toru Kawanishi, Akira Takahara
    • Journal Title

      J. Pharmacol. Sci

      Volume: 109(3) Pages: 327-333

    • NAID

      10025734834

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590293
  • [Journal Article] Involvement of the Na^+/Ca^<2+> exchanger in the automaticity of guinea-pig pulmonary vein myocardium as revealed by SEA04002009

    • Author(s)
      Iyuki Namekata, Yayoi Tsuneoka, Akira Takahara, Hideaki Shimada, Takahiko Sugimoto, Kiyoshi Takeda, Midori Nagaharu, Koki Shigenobu, Toru Kawanishi, Hikaru Tanaka
    • Journal Title

      J. Pharmacol. Sci

      Volume: 110(1) Pages: 111-116

    • NAID

      10025736868

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590293
  • [Journal Article] 抗体医薬の現状と展望2008

    • Author(s)
      川西 徹
    • Journal Title

      日薬理誌 131

      Pages: 102-108

    • NAID

      10024186656

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590163
  • [Journal Article] 「研究成果報告書概要(欧文)」より2008

    • Author(s)
      Toru KAWANISHI
    • Journal Title

      Nippon Yakurigaku Zasshi 131

      Pages: 102-108

    • Data Source
      KAKENHI-PROJECT-18590163
  • [Journal Article] Intracellular mechanisms and receptor types for endothelin-1-induced positive and negative inotropy in mouse ventricular myocardium.2008

    • Author(s)
      Iyuki Namekata, Shinpei Fujiki, Yuko Kawakami, Rina Moriwaki, Kentaro Takeda, Toru Kawanishi, Akira Takahara, Koki Shigenobu, Hikaru Tanaka
    • Journal Title

      Naunyn-Schmied. Arch. Pharmacol 376(6)

      Pages: 385-395

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20890233
  • [Journal Article] Caspase cascade proceeds rapidly after cytochrome c release from mitochondria in tumor necrosis factor-alpha-induced cell death.2007

    • Author(s)
      Kawai H, Suzuki T, Kobayashi T, Momose K, Hayakawa T, Kawanishi Tら
    • Journal Title

      Journal of Pharmacological Science 103

      Pages: 159-167

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300160
  • [Journal Article] Caspase cascade proceeds rapidly after cytochrome c release from mitochondria in tumor necrosis factor-alpha-induced cell death.2007

    • Author(s)
      Kawai H, Suzuki T, Kobayashi T, Ishii-Watabe A, Sakurai H, Ohata H, Honda K, Momose K, Hayakawa T, Kawanishi T
    • Journal Title

      J Pharmacol ScL. 103

      Pages: 159-67

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300160
  • [Journal Article] Quantitative fluorescence measurement of cardiac Na^+/Ca^+ exchanger inhibition by kinetic analysis in stably transfected HEK293 cells.2006

    • Author(s)
      Namekata I, Kawanishi T, Iida-Tanaka H, Tanaka H, Shigenobu K
    • Journal Title

      Journal of Pharmacological Science 101

      Pages: 356-360

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300160
  • [Journal Article] Reduction by SEA0400 of myocardial ischemia-induced cytoplasmic and mitochondrial Ca^<2+> overload.2006

    • Author(s)
      Namekata I, Shimada H, Kawanishi T, Tanaka H, Shigenobu K
    • Journal Title

      European Journal of Pharmacology 543

      Pages: 108-115

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300160
  • [Journal Article] Quantitative fluorescence measurement of cardiac Na+/Ca+ exchanger inhibition by kinetic analysis in stably transfected HEK293 cells.2006

    • Author(s)
      Namekata I, Kawanishi T, Iida-Tanaka H, Tanaka H, Shigenobu K
    • Journal Title

      J. Pharmacol. ScL. 101

      Pages: 356-360

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300160
  • [Journal Article] Reduction by SEA0400 of myocardial ischemia-induced cytoplasmic and mitochondrial Ca2+ overload.2006

    • Author(s)
      Namekata I, Shimada H, Kawanishi T, Tanaka H, Shigenobu K
    • Journal Title

      Eur J PharmacoL 543

      Pages: 108-115

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300160
  • [Journal Article] Simultaneous imaging of initiator/effector caspase activity and mitochondrial membrane potential during cell death in living HeLa cells.2004

    • Author(s)
      Kawai H, Suzuki T, Kobayashi T, Mizuguchi H, Kawanishi T ら
    • Journal Title

      Biochemistry Biophysical Acta 1693

      Pages: 101-110

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300160
  • [Journal Article] Simultaneous imaging of initiator / effector caspase activity and mitochondrial membrane potential during cell death in living HeLa cells.2004

    • Author(s)
      Kawai H, Suzuki T, Kobayashi T, Mizuguchi H, Hayakawa T, Kawanishi T
    • Journal Title

      Biochim. Biophys. Acta 1693

      Pages: 101-110

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300160
  • [Presentation] モルモット肺静脈心筋自発活動における細胞内Ca^<2+>動態と電気生理学的性質2011

    • Author(s)
      恒岡弥生、行方衣由紀、川西徹、田中光
    • Organizer
      第125回日本薬理学会関東部会
    • Place of Presentation
      日本大学薬学部
    • Year and Date
      2011-10-15
    • Data Source
      KAKENHI-PROJECT-21590293
  • [Presentation] モルモットおよびラット肺静脈心筋の電気的自発活動とカルシウム動態2011

    • Author(s)
      恒岡弥生、秋葉明子、行方衣由紀、高原章、川西徹、田中光
    • Organizer
      第84回日本薬理学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-21590293
  • [Presentation] Effects of SERCA activators, ellagic acid and gingerol, on diabetes mellitus-induced diastolic dysfunction in isolated murine ventricular myocardia2010

    • Author(s)
      Iyuki Namekata, Minato Ohhara, Yoshitaka Hirota, Toru Kawanishi, Akira Takahara, Hikaru Tanaka
    • Organizer
      The 16th World Congress of Basic and Clinical Pharmacology(World Pharma 2010)
    • Place of Presentation
      Copenhagen, Denmark
    • Data Source
      KAKENHI-PROJECT-21590293
  • [Presentation] マウス心室筋の興奮収縮機構の発達変化:薬理学的検討および画像化解析2010

    • Author(s)
      行方衣由紀、川上悠子、濱口省吾、川西徹、高原章、田中光
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-21590293
  • [Presentation] モルモット肺静脈心筋の組織・細胞の形態および自発活動2010

    • Author(s)
      恒岡弥生、行方衣由紀、高原章、川西徹、田中光
    • Organizer
      第19回日本バイオイメージング学会学術集会
    • Place of Presentation
      慶應義塾大学日吉キャンパス
    • Data Source
      KAKENHI-PROJECT-21590293
  • [Presentation] Electrophysiological and pharmacological properties of the isolated guinea-pig pulmonary vein myocardium2009

    • Author(s)
      Iyuki Namekata, Yayoi Tsuneoka, Takahiko Sugimoto, Kiyoshi Takeda, Toru Kawanishi, Ryu Nakamura, Akira Takahara, Hikaru Tanaka
    • Organizer
      The 36th Congress of the International Union of Physiological Sciences(IUPS2009)
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-21590293
  • 1.  NAMEKATA Iyuki (30510309)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 11 results
  • 2.  TANAKA Hikaru (40236617)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 11 results
  • 3.  TAKAHARA Akira (80377481)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 10 results
  • 4.  HAYAKAWA Takao (50124392)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  WATABE Akiko (50291117)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  TANAKA Naoko (40184353)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  TAKAHASHI Michito (30080005)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  UCHIDA Eriko (80176685)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  KAWAI Hiroshi (20321854)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  NAGAO Taku (30217971)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  AKAHANE Satomi (00184185)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  KUROSE Hitoshi (10183039)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  HINAMITANI Haruyuki (70051779)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  TANISHITA Kazuo (10101776)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  SUEMATSU Makoto (00206385)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  SUZUKI Takuo (10415466)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  TAKAHASHI Atsushi (20111106)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  OMORI Yoshihito (50079307)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  OHNO Yasuo (30111107)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  重信 弘毅 (50012654)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  畝山 智香子 (30206817)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  YOKOTA Isue
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  OHTA Miyako
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  TOYODA Kazuhiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  関塚 永一
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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