KAWANISHI Toru 川西徹

… Alternative Names

KAWANISHI Tooru 川西徹

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Researcher Number	40124383
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2012: 国立衛生試験所, 部長 2011: 国立医薬品食品衛生研究所, 副所長 2009: 国立衛生試験所, 部長 2006 – 2007: 国立医薬品食品衛生研究所, 薬品部, 部長 2004 – 2006: 国立医薬品食品衛生研究所, 生物薬品部, 部長 … More 2002: National Institute of Health Sciences, Head, 所長 2002: 国立医薬品食品衛生研究所, 生物薬品部, 部長 2001: 国立医薬品食品衛生研究所, 生物薬品部, 室長 1997 – 1999: 国立医薬品食品衛生研究所, 生物薬品部, 室長 1995 – 1996: National Institute of Health Sciences, Division of Biological Chemistry and Biologicals, Chief, 生物薬品部, 室長 1994: 国立衛生試験所, 病理部, 室長 1986: Researcher, Section of biochemical Pharmacology, Biological Safety Research Cent, 薬理部, 研究員 Less
Review Section/Research Field	Principal Investigator General pharmacology / Medical pharmacy Except Principal Investigator General pharmacology / General pharmacology / Biomedical engineering/Biological material science / Biological pharmacy
Keywords	Principal Investigator 蛍光プローブ / FcRn / FRET / カルシウムイオン / 共焦点レーザー走査顕微鏡 / serum half life / protein drugs / receptor / Fc domain / 体内動態 … More / タンバク質 / 医薬品 / タンパク質 / 血中半減期 / タンパク質性医薬品 / 受容体 / Fcドメイン / fluorescence microscopy / Green Fluorescence Protein / fluorescence probe / SH2 domain / tyrosine phosphorylation / src-類似領域 / 画像解析 / SHドメイン / 蛍光顕微鏡 / GFP / SH2ドメイン / チロシンリン酸化 / hepatocyte / liver / fluorescent probes / calcium wave / calcium ion / confocal laser scanning microscopy / レーザー顕微鏡 / 肝細胞 / カルシウムウェーブ / 心筋細胞 / カルシウムスパーク … More Except Principal Investigator イメージング / Ca^<2+>チャネル / 自動能 / 肺静脈心筋 / Ca^<2+>交換機構 / Na^+ / Freshly isolated renal cells / Renal cells / 実験モデル / 腎毒性 / 単離細胞 / 腎臓 / Pd-porphyrin / Oxygen tension / Blood flow / Microcirculation / Phosphorescence / Fluorescense / Nano-probes / Bioimaging / 糖尿病 / 螢光 / Pdポルフィリン / 酸素分圧 / 血流 / 微小循環 / 燐光 / 蛍光 / ナノプローブ / バイオイメージング / cardiac hypertrophy / cardiac myocyte / C^<2+> channel / Ca^<2+> signaling / seven transmembrane / G protein / oxidative stress / reactive oxygen species / リアノジン受容体 / カルシウムチャネル / カルシウムシグナリング / 興奮収縮連関 / システイン / G-タンパク質 / 心肥大 / 心筋細胞 / Ca^<2+>シグナル / 7回膜貫通型受容体 / Gタンパク質 / 酸化ストレス / 活性酸素 / カルシウム / 心房細動 / カルシウムイメージング / 薬理学 / T型カルシウムチャネル / 筋小胞体 / Na^+/Ca^<2+>交換機構 / 肺動脈心筋 / 細胞内カルシウム / ナトリウムカルシウム交換機構 / ミトコンドリア / ナトリウム・カルシウム交換機構 / 虚血再灌流障害 / 心筋 Less

Spatio-temporal analysis of intracellularcalcium oscillation in the pulmonary vein myocardium
- Principal Investigator
  
  NAMEKATA Iyuki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Toho University
The role of intracellular calcium and sodium-calcium exchanger in the automaticity of pulmonary vein myocardium.
- Principal Investigator
  
  TANAKA Hikaru
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Toho University
Fluorescence imaging analysis of Na^+/Ca^<2+> exchanger dynamics in myocardial ischemia reperfusion injury
- Principal Investigator
  
  NAMEKATA Iyuki
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  General pharmacology
- Research Institution
  Toho University
Studies on molecular basis of the pharmacokinetic regulation of protein drugs consisting of immunoglobulin Fc regionPrincipal Investigator
- Principal Investigator
  
  KAWANISHI Toru
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  National Institute of Health Sciences
Development of Photonic-imaging System with Fluorescent and Phosphorescent Nano-probes
- Principal Investigator
  
  HINAMITANI Haruyuki
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Keio University
Novel Therapeutic Strategy for Heart Failure : Molecular Mechanism underlying the Regulation of Ca^<2+> Signaling in the Heart
- Principal Investigator
  
  NAGAO Taku
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  National Institute of Health Sciences
Development of Real-time Imaging Method of Protein Tyrosine PhosphorylationPrincipal Investigator
- Principal Investigator
  
  KAWANISHI Toru
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  National Institute of Health Sciences
細胞内カルシウムスパーク現象の分子メカニズムの研究Principal Investigator
- Principal Investigator
  
  川西徹
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  国立衛生試験所
Study on molecular Mechanism of Calcium Waves Using Rapid Scanning Confocal MicroscopyPrincipal Investigator
- Principal Investigator
  
  KAWANISHI Toru
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  National Institute of Health Sciences
Freshly isolated renal cells as a experimental model system for studying the chemically induced renal injury.
- Principal Investigator
  
  TAKAHASHI Atsushi
- Project Period (FY)
  1984 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  National Institute of Hygienic Sciences.

All 2011 2010 2009 2008 2007 2006 2004

All Journal Article Presentation

[Journal Article] Involvement of the Na+/Ca2+ exchanger in the automaticity of guinea-pig pulmonary vein myocardium as revealed by SEA0400.2009
- Author(s)
  Iyuki Namekata, Yayoi Tsuneoka, Akira Takahara, Hideaki Shimada, Takahiko Sugimoto, Kiyoshi Takeda, Midori Nagaharu, Koki Shigenobu, Toru Kawanishi, Hikaru Tanaka
- Journal Title
  
  J. Pharmacol. Sci 110(1)
  
  Pages: 111-116
- NAID
  10025736868
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890233
[Journal Article] New aspects for the treatment of cardiac diseases based on the diversity of functional controls on cardiac muscles: diversity in the excitation-contraction mechanisms of the heart.2009
- Author(s)
  Hikaru Tanaka, Iyuki Namekata, Hideaki Nouchi, Koki Shigenobu, Toru Kawanishi, Akira Takahara
- Journal Title
  
  J. Pharmacol. Sci 109(3)
  
  Pages: 327-333
- NAID
  10025734834
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890233
[Journal Article] New aspects for the treatment of cardiac diseases based on the diversity of functional controls on cardiac muscles : diversity in the excitation-contraction mechanisms of the heart2009
- Author(s)
  Hikaru Tanaka, Iyuki Namekata, Hideaki Nouchi, Koki Shigenobu, Toru Kawanishi, Akira Takahara
- Journal Title
  
  J. Pharmacol. Sci
  
  Volume: 109(3) Pages: 327-333
- NAID
  10025734834
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590293
[Journal Article] Involvement of the Na^+/Ca^<2+> exchanger in the automaticity of guinea-pig pulmonary vein myocardium as revealed by SEA04002009
- Author(s)
  Iyuki Namekata, Yayoi Tsuneoka, Akira Takahara, Hideaki Shimada, Takahiko Sugimoto, Kiyoshi Takeda, Midori Nagaharu, Koki Shigenobu, Toru Kawanishi, Hikaru Tanaka
- Journal Title
  
  J. Pharmacol. Sci
  
  Volume: 110(1) Pages: 111-116
- NAID
  10025736868
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590293
[Journal Article] 抗体医薬の現状と展望2008
- Author(s)
  川西徹
- Journal Title
  
  日薬理誌 131
  
  Pages: 102-108
- NAID
  10024186656
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590163
[Journal Article] 「研究成果報告書概要(欧文)」より2008
- Author(s)
  Toru KAWANISHI
- Journal Title
  
  Nippon Yakurigaku Zasshi 131
  
  Pages: 102-108
- Data Source
  KAKENHI-PROJECT-18590163
[Journal Article] Intracellular mechanisms and receptor types for endothelin-1-induced positive and negative inotropy in mouse ventricular myocardium.2008
- Author(s)
  Iyuki Namekata, Shinpei Fujiki, Yuko Kawakami, Rina Moriwaki, Kentaro Takeda, Toru Kawanishi, Akira Takahara, Koki Shigenobu, Hikaru Tanaka
- Journal Title
  
  Naunyn-Schmied. Arch. Pharmacol 376(6)
  
  Pages: 385-395
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890233
[Journal Article] Caspase cascade proceeds rapidly after cytochrome c release from mitochondria in tumor necrosis factor-alpha-induced cell death.2007
- Author(s)
  Kawai H, Suzuki T, Kobayashi T, Momose K, Hayakawa T, Kawanishi Tら
- Journal Title
  
  Journal of Pharmacological Science 103
  
  Pages: 159-167
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16300160
[Journal Article] Caspase cascade proceeds rapidly after cytochrome c release from mitochondria in tumor necrosis factor-alpha-induced cell death.2007
- Author(s)
  Kawai H, Suzuki T, Kobayashi T, Ishii-Watabe A, Sakurai H, Ohata H, Honda K, Momose K, Hayakawa T, Kawanishi T
- Journal Title
  
  J Pharmacol ScL. 103
  
  Pages: 159-67
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300160
[Journal Article] Quantitative fluorescence measurement of cardiac Na^+/Ca^+ exchanger inhibition by kinetic analysis in stably transfected HEK293 cells.2006
- Author(s)
  Namekata I, Kawanishi T, Iida-Tanaka H, Tanaka H, Shigenobu K
- Journal Title
  
  Journal of Pharmacological Science 101
  
  Pages: 356-360
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16300160
[Journal Article] Reduction by SEA0400 of myocardial ischemia-induced cytoplasmic and mitochondrial Ca^<2+> overload.2006
- Author(s)
  Namekata I, Shimada H, Kawanishi T, Tanaka H, Shigenobu K
- Journal Title
  
  European Journal of Pharmacology 543
  
  Pages: 108-115
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16300160
[Journal Article] Quantitative fluorescence measurement of cardiac Na+/Ca+ exchanger inhibition by kinetic analysis in stably transfected HEK293 cells.2006
- Author(s)
  Namekata I, Kawanishi T, Iida-Tanaka H, Tanaka H, Shigenobu K
- Journal Title
  
  J. Pharmacol. ScL. 101
  
  Pages: 356-360
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300160
[Journal Article] Reduction by SEA0400 of myocardial ischemia-induced cytoplasmic and mitochondrial Ca2+ overload.2006
- Author(s)
  Namekata I, Shimada H, Kawanishi T, Tanaka H, Shigenobu K
- Journal Title
  
  Eur J PharmacoL 543
  
  Pages: 108-115
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300160
[Journal Article] Simultaneous imaging of initiator/effector caspase activity and mitochondrial membrane potential during cell death in living HeLa cells.2004
- Author(s)
  Kawai H, Suzuki T, Kobayashi T, Mizuguchi H, Kawanishi T ら
- Journal Title
  
  Biochemistry Biophysical Acta 1693
  
  Pages: 101-110
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16300160
[Journal Article] Simultaneous imaging of initiator / effector caspase activity and mitochondrial membrane potential during cell death in living HeLa cells.2004
- Author(s)
  Kawai H, Suzuki T, Kobayashi T, Mizuguchi H, Hayakawa T, Kawanishi T
- Journal Title
  
  Biochim. Biophys. Acta 1693
  
  Pages: 101-110
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300160
[Presentation] モルモット肺静脈心筋自発活動における細胞内Ca^<2+>動態と電気生理学的性質2011
- Author(s)
  恒岡弥生、行方衣由紀、川西徹、田中光
- Organizer
  第125回日本薬理学会関東部会
- Place of Presentation
  日本大学薬学部
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-21590293
[Presentation] モルモットおよびラット肺静脈心筋の電気的自発活動とカルシウム動態2011
- Author(s)
  恒岡弥生、秋葉明子、行方衣由紀、高原章、川西徹、田中光
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21590293
[Presentation] Effects of SERCA activators, ellagic acid and gingerol, on diabetes mellitus-induced diastolic dysfunction in isolated murine ventricular myocardia2010
- Author(s)
  Iyuki Namekata, Minato Ohhara, Yoshitaka Hirota, Toru Kawanishi, Akira Takahara, Hikaru Tanaka
- Organizer
  The 16th World Congress of Basic and Clinical Pharmacology(World Pharma 2010)
- Place of Presentation
  Copenhagen, Denmark
- Data Source
  KAKENHI-PROJECT-21590293
[Presentation] マウス心室筋の興奮収縮機構の発達変化:薬理学的検討および画像化解析2010
- Author(s)
  行方衣由紀、川上悠子、濱口省吾、川西徹、高原章、田中光
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21590293
[Presentation] モルモット肺静脈心筋の組織・細胞の形態および自発活動2010
- Author(s)
  恒岡弥生、行方衣由紀、高原章、川西徹、田中光
- Organizer
  第19回日本バイオイメージング学会学術集会
- Place of Presentation
  慶應義塾大学日吉キャンパス
- Data Source
  KAKENHI-PROJECT-21590293
[Presentation] Electrophysiological and pharmacological properties of the isolated guinea-pig pulmonary vein myocardium2009
- Author(s)
  Iyuki Namekata, Yayoi Tsuneoka, Takahiko Sugimoto, Kiyoshi Takeda, Toru Kawanishi, Ryu Nakamura, Akira Takahara, Hikaru Tanaka
- Organizer
  The 36th Congress of the International Union of Physiological Sciences(IUPS2009)
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-21590293

1. NAMEKATA Iyuki (30510309)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
2. TANAKA Hikaru (40236617)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
3. TAKAHARA Akira (80377481)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
4. HAYAKAWA Takao (50124392)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. WATABE Akiko (50291117)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. TANAKA Naoko (40184353)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TAKAHASHI Michito (30080005)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. UCHIDA Eriko (80176685)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KAWAI Hiroshi (20321854)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. NAGAO Taku (30217971)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. AKAHANE Satomi (00184185)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KUROSE Hitoshi (10183039)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. HINAMITANI Haruyuki (70051779)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. TANISHITA Kazuo (10101776)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. SUEMATSU Makoto (00206385)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. SUZUKI Takuo (10415466)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. TAKAHASHI Atsushi (20111106)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. OMORI Yoshihito (50079307)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. OHNO Yasuo (30111107)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 重信弘毅 (50012654)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 畝山智香子 (30206817)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. YOKOTA Isue

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. OHTA Miyako

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. TOYODA Kazuhiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 関塚永一

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KAWANISHI Toru 川西 徹

KAWANISHI Tooru 川西 徹

Research Projects

Research Products

Co-Researchers

Spatio-temporal analysis of intracellularcalcium oscillation in the pulmonary vein myocardium

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of intracellular calcium and sodium-calcium exchanger in the automaticity of pulmonary vein myocardium.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Fluorescence imaging analysis of Na^+/Ca^<2+> exchanger dynamics in myocardial ischemia reperfusion injury

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on molecular basis of the pharmacokinetic regulation of protein drugs consisting of immunoglobulin Fc regionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of Photonic-imaging System with Fluorescent and Phosphorescent Nano-probes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Novel Therapeutic Strategy for Heart Failure : Molecular Mechanism underlying the Regulation of Ca^<2+> Signaling in the Heart

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of Real-time Imaging Method of Protein Tyrosine PhosphorylationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

細胞内カルシウムスパーク現象の分子メカニズムの研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on molecular Mechanism of Calcium Waves Using Rapid Scanning Confocal MicroscopyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Freshly isolated renal cells as a experimental model system for studying the chemically induced renal injury.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Involvement of the Na+/Ca2+ exchanger in the automaticity of guinea-pig pulmonary vein myocardium as revealed by SEA0400.2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] New aspects for the treatment of cardiac diseases based on the diversity of functional controls on cardiac muscles: diversity in the excitation-contraction mechanisms of the heart.2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] New aspects for the treatment of cardiac diseases based on the diversity of functional controls on cardiac muscles : diversity in the excitation-contraction mechanisms of the heart2009

Author(s)

Journal Title

NAID

Data Source

KAWANISHI Toru 川西徹

KAWANISHI Tooru 川西徹