• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

OTSUKA MASAMI  大塚 雅巳

ORCIDConnect your ORCID iD *help
… Alternative Names

OTSUKA Masami  大塚 雅巳

大塚 雅巳  オオツカ マサミ

Less
Researcher Number 40126008
Other IDs
External Links
Affiliation (Current) 2025: 熊本大学, 薬学部, 客員教授
Affiliation (based on the past Project Information) *help 2018 – 2023: 熊本大学, 大学院生命科学研究部(薬), 客員教授
2016 – 2018: 熊本大学, 大学院生命科学研究部(薬), 教授
2013 – 2016: 熊本大学, 大学院生命科学研究部, 教授
2015: 熊本大学, 大学院生命科学研究部(薬学系), 教授
2013: 熊本大学, 大学院生命科学研究部(薬), 教授 … More
2012 – 2013: 熊本大学, 生命科学研究部, 教授
2009 – 2011: Kumamoto University, 大学院・生命科学研究部, 教授
2007 – 2008: Kumamoto University, Faculty of Medical and Pharmaceutical Sciences, Professor
2007: Kumamoto University, その他の研究科, 教授
2006: 熊本大学, 大学院医学薬学研究部, 教授
2003 – 2005: 熊本大学, 大学院・医学薬学研究部, 教授
2001 – 2002: Kumamoto University, Graduate School of Pharmaceutical Sciences, Professor, 大学院・薬学研究科, 教授
2001: 熊本大学, 大学院・薬学研究科, 助教授
1997 – 2000: Kumamoto Univ.Dept.Pharm.Sci., Prof., 薬学部, 教授
1993 – 1996: 京都大学, 化学研究所, 助教授
1990 – 1991: 東京大学, 薬学部, 助手 Less
Review Section/Research Field
Principal Investigator
Drug development chemistry / 医薬分子機能学 / Chemical pharmacy / Physical pharmacy / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Biological Sciences
Except Principal Investigator
Drug development chemistry / Virology / 医薬分子機能学 / Inorganic chemistry … More / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Neurosurgery / Pharmacology in pharmacy / Bioorganic chemistry / Synthetic chemistry Less
Keywords
Principal Investigator
HIV-EP1 / NFκB / ブレオマイシン / Sp1 / 人工配位子 / NFkB / 活性酸素 / エイズウイルス / 亜鉛蛋白質 / ファルネシルトランスフェラーゼ … More / アポトーシス / NF-κB / zinc protein / HIV / AIDS virus / Spl / HIV-EPl / 脳保護薬 / 脳保護 / 癌 / 脳神経疾患 / DNA切断 / Ras蛋白質 / 抗がん剤 / アポトーシス耐性細胞 / メルカプト化合物 / 亜鉛フィンガー / Z型DNA / ニッケル(III) / 酸素活性化 / Vpx / SFX / IP6 / MA / ナファモスタット / ADAM17 / TGF-b/Smad / COVID-19 / 全身性強皮症 / 薬学 / HNE / molecular target / chelator / cancer / 分子標的 / 配位子 / がん / zinc complex / ナフチル基 / ヒドロキサム酸 / 亜鉛錯体 / peptide nucleic acids / artificial ligand / ペプチド核酸 / Ras protein / oncogene / farnesyltransferase / man-made chelator / 癌遺伝子 / Man-made ligand / anti-cancer agent / active oxygen / apoptosis resistant cell / apoptosis / scyllo-イノシトール / 亜鉛キレーター / アミロイドβ / アルツハイマー病 / 脳腫瘍薬 / TGF-β/Smad経路 / TGF-b/Smad 経路 / PI3K/Akt 経路 / TGF-b/Smad経路 / PI3K/Akt経路 / 強皮症 / TGF‐β/Smad経路 / PI3K/Akt経路 / プロテアソーム分解 / HIV-1 / APOBEC3G / Vif / 抗エイズ薬 / NFкB / DNA架橋 / HMGA蛋白質 / Akt / イノシトール / シグナル伝達 / ras遺伝子 / インスリン / コノフィリン / グルタチオンSトランスフェラーゼ / グルタチオン / 鉄錯体 / ファルネシル化 / K-ras-NRK細胞 / 亜鉛酵素 / ファルネシルチランスフェラーゼ / GyrB / ノベナミン / ノボビオシン / X線結晶構造解析 / がん遺伝子 / DNA結合阻害 / 亜鉛フィンガー蛋白質 / 細胞内シグナル伝達 / Re1 / ヒドロキシルラジカル / イミダゾ-ル / 軸配位子 / 自己不活化 / 不斉酸化 … More
Except Principal Investigator
活性酸素 / アポトーシス / 転写因子 / 浸潤・転移 / 癌 / Gag / HIV / シグナル伝達 / HIV根絶 / IP6 / X線結晶解析 / プロドラッグ体 / イノシトールリン脂質 / C-1027 / CD40 / Rel / エンジイン / DNA切断 / DNA / 亜鉛配位子 / ADAM17 / 亜鉛キレーター / ウイルス / MA / 分子設計 / 生理活性 / タンパク質発現 / Gag MAドメイン / HIV Gagタンパク質 / HIV潜伏感染細胞 / エイズ完全治癒 / プロドラッグ / エイズ根絶 / 治療開発 / バイオマーカー / 上皮ー間葉転換 / 脳悪性リンパ腫 / BCL2タンパク / MYCタンパク / 予後因子 / 新規治療開発 / 上皮間葉転換因子 / 脳腫瘍 / 上皮間葉転換 / 晩期障害 / 放射線治療 / 浸潤 / 上衣腫 / 悪性脳腫瘍 / 上皮ー間葉転換誘導因子 / 治療標的分子 / 転移、浸潤能 / 治療抵抗性 / 脳原発悪性リンパ腫 / 脂質 / 薬学 / 感染症 / 細胞内導入キャリア / DSFアッセイ / HIV放出抑制 / X線構造解析 / エイズ根治 / 誘導体 / フィチン酸 / 潜伏感染細胞 / エイズ完治 / Rasタンパク / パーキンソン病 / オルタナティブ活性化 / MAPキナーゼ / ケモカイン / アルギナーゼ / サイトカイン / 一酸化窒素合成酵素 / 神経保護 / 核内受容体 / ミクログリア / Molecular design / Esperamicin / Dynemicin / Enediyne / Radical formation / DNA cleavage / Antitumor antibiotic / 作用発現機構 / 抗癌活性 / DNA認識 / DNA設計 / 抗生物質 / エスペラミシン / ダイナミシン / ラジカル発生 / 抗癌抗生物質 / NFkappaB / Apoptosis / B cell differentiation / Transcription factor / Signal transduction / 分子生物学 / Re1 / NFkB / B細胞分化 / Human Geome / Triple Stranded DNA / Nuclease / Zinc Finger / DNA Cutting / Bleomycin / Artificial Restriction Enzymo / グリシル・グリシル・ヒスチジン / ニッケル錯体 / 人工リプレッサー / DNA結合蛋白質 / 塩基配列特異性 / ヒトゲノム / ヒト・ゲノム / 3本鎖DNA / ヌクレアーゼ / 亜鉛フィンガー / ブレオマイシン / 人工制限酵素 / Photodynamic Therapy / Active Oxygen / Intercalation / Molecular Recognition / Hybrid Compound / Antifungal Activity / Bioactivity / 生物機能 / 有機無機複合体 / シッフ塩基 / 血糖値の制御 / 配糖錯体 / 光線力学療法 / インターカレーション / 分子認識 / 複合体 / 抗菌活性 / 亜鉛蛋白質 / FLAG / BIACore / Gag(p17) / PLCδ_1 PH / 蛋白質 / HIV-1 / Biacore / Vpu / NC / イノシトールリン酸 / エイズ / 合成化学 / 画像 / 螢光 / 機能性分子 / 生体機能 / 一酸化窒素 / 酸素化酵素 / 光感受性色素 / インスリン / 精密金属錯体 / 微量金属イオン / 複合系金属錯体 Less
  • Research Projects

    (47 results)
  • Research Products

    (350 results)
  • Co-Researchers

    (42 People)
  •  Development of therapeutic drugs that tandemly suppress infection, lung fibrosis, and malignant transformation of the new coronavirusPrincipal Investigator

    • Principal Investigator
      大塚 雅巳
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
    • Research Institution
      Kumamoto University
  •  Structure optimization of compounds to confine HIV in a cell and induce apoptosis aiming at drugs

    • Principal Investigator
      Fujita Mikako
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
    • Research Institution
      Kumamoto University
  •  Development of a method to induce apoptosis by HIV locked in a cell

    • Principal Investigator
      Fujita Mikako
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Kumamoto University
  •  Development of the novel diagnostic and treatment strategies targeting at Epithelial to mesenchymal transition related transcription factors in primary central nervous system lymphomas

    • Principal Investigator
      MAKINO KEISHI
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurosurgery
    • Research Institution
      Kumamoto University
  •  Development and optimization of leads for multifactorial disease systemic sclerosisPrincipal Investigator

    • Principal Investigator
      Otsuka Masami
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Drug development chemistry
    • Research Institution
      Kumamoto University
  •  Development of a novel brain protectantPrincipal Investigator

    • Principal Investigator
      Otsuka Masami
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Drug development chemistry
    • Research Institution
      Kumamoto University
  •  SFXを用いたHIVアクセサリータンパク質と宿主制限因子の複合体の動的構造の解明Principal Investigator

    • Principal Investigator
      大塚 雅巳
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Research Field
      Physical pharmacy
    • Research Institution
      Kumamoto University
  •  Design and synthesis of a compound targeting amyloid beta aiming at the cure of Alzheimer's diseasePrincipal Investigator

    • Principal Investigator
      Otsuka Masami
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Drug development chemistry
    • Research Institution
      Kumamoto University
  •  Establishment of assay system for drugs that regulate microglia via transcription factors

    • Principal Investigator
      KATSUKI Hiroshi
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pharmacology in pharmacy
    • Research Institution
      Kumamoto University
  •  Development of anticancer agents for zinc-proteins related to cancer

    • Principal Investigator
      OKAMOTO Yoshinari
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Drug development chemistry
    • Research Institution
      Kumamoto University
  •  Design and synthesis of anti-brain tumor and brain-protective drugs using brain-targeting peptidesPrincipal Investigator

    • Principal Investigator
      OTSUKA Masami
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Drug development chemistry
    • Research Institution
      Kumamoto University
  •  Development of medicinal molecules having biologically functions targeting the PI3K/Akt pathway and the TGF-b/Smad pathwayPrincipal Investigator

    • Principal Investigator
      OTSUKA Masami
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Drug development chemistry
    • Research Institution
      Kumamoto University
  •  Development of inhibitors of cancer cell invasion targetting to ADAM17 or transcription factor Snail.

    • Principal Investigator
      OKAMOTO Yoshinari
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Drug development chemistry
    • Research Institution
      Kumamoto University
  •  Design and synthesis of anti-HIV agents that inhibit the Vif-mediated proteasome degradation of APOBEC3GPrincipal Investigator

    • Principal Investigator
      OTSUKA Masami
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Drug development chemistry
    • Research Institution
      Kumamoto University
  •  Design of DNA-cleaving and -crosslinking agents based on NFκB and HMGA proteins aiming at the application to cancer therapyPrincipal Investigator

    • Principal Investigator
      OTSUKA Masami
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Drug development chemistry
    • Research Institution
      Kumamoto University
  •  Development of zinc chelators to inhibit function of zinc protein participating in invasion and metastasis of cancer cell

    • Principal Investigator
      OKAMOTO Yoshinari
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Drug development chemistry
    • Research Institution
      Kumamoto University
  •  Regulation of HIV replication by inositol phosphates

    • Principal Investigator
      FUJITA Mikako
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Kumamoto University
  •  イノシトール結合ドメインをもつ蛋白質を標的とした新規脳保護薬の分子設計Principal Investigator

    • Principal Investigator
      大塚 雅巳
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Drug development chemistry
    • Research Institution
      Kumamoto University
  •  Development of zinc chelators with protein specificity aiming at molecular target therapy of cancerPrincipal Investigator

    • Principal Investigator
      OTSUKA Masami
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Drug development chemistry
    • Research Institution
      Kumamoto University
  •  新規ビスインドール化合物コノフィリンを基盤とした糖尿病薬の設計と合成Principal Investigator

    • Principal Investigator
      大塚 雅巳
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Drug development chemistry
    • Research Institution
      Kumamoto University
  •  Rasファルネシルトランスフェラーゼの亜鉛部位を標的とした抗がん剤の創製Principal Investigator

    • Principal Investigator
      大塚 雅巳
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kumamoto University
  •  DNA切断分子集合体の創製とゲノム創薬への応用Principal Investigator

    • Principal Investigator
      大塚 雅巳
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Drug development chemistry
    • Research Institution
      Kumamoto University
  •  Molecular design of anti-AIDS drugs targeting the viral and host zinc proteinsPrincipal Investigator

    • Principal Investigator
      OTSUKA Masami
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Drug development chemistry
    • Research Institution
      Kumamoto University
  •  蛋白質を会合させる人工分子の開発とそれを用いた細胞応答の制御Principal Investigator

    • Principal Investigator
      大塚 雅巳
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      医薬分子機能学
    • Research Institution
      Kumamoto University
  •  Molecular design of anti-AIDS drugs targeting the human transcription machinery employed for the replication of AIDS virusPrincipal Investigator

    • Principal Investigator
      OTSUKA Masami
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      医薬分子機能学
    • Research Institution
      Kumamoto University
  •  硫黄-亜鉛間の結合形成を作用機序とする抗がん、抗エイズ医薬の分子設計と合成Principal Investigator

    • Principal Investigator
      大塚 雅巳
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kumamoto University
  •  画像化能を有する生体機能探査分子の設計原理の開発

    • Principal Investigator
      樋口 恒彦
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      医薬分子機能学
    • Research Institution
      The University of Tokyo
  •  Development of compounds for multiple regulation of intracellular signalingPrincipal Investigator

    • Principal Investigator
      OTSUKA Masami
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      医薬分子機能学
    • Research Institution
      Kumamoto University
  •  Molecular Design of Ras Farnesyltransferase InhibitorsPrincipal Investigator

    • Principal Investigator
      OTSUKA Masami
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      医薬分子機能学
    • Research Institution
      Kumamoto University
  •  硫黄-亜鉛間の結合形成を作用機序とする抗がん、抗エイズ医薬の分子設計と合成Principal Investigator

    • Principal Investigator
      大塚 雅巳
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kumamoto University
  •  アポトーシスに関わる細胞内情報伝達の制御をめざした化合物の分子設計と機能解析Principal Investigator

    • Principal Investigator
      大塚 雅巳
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kumamoto University
  •  硫黄-亜鉛間の結合形成を作用機序とする抗がん、抗エイズ医薬の分子設計と合成Principal Investigator

    • Principal Investigator
      大塚 雅巳
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kumamoto University
  •  精密金属錯体の分子設計と生体機能

    • Principal Investigator
      長野 哲雄
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Inorganic chemistry
    • Research Institution
      The University of Tokyo
  •  Molecular design and synthesis of anti-cancer compounds that cause apoptosisPrincipal Investigator

    • Principal Investigator
      OTSUKA Masami
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      医薬分子機能学
    • Research Institution
      Kumamoto University
  •  複合系金属錯体による生物機能の制御

    • Principal Investigator
      YANO Shigenobu
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Inorganic chemistry
    • Research Institution
      Nara Women's University
  •  がん遺伝子関連タンパク質のクロストークを制御する化合物の設計と合成Principal Investigator

    • Principal Investigator
      大塚 雅巳
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      医薬分子機能学
    • Research Institution
      Kyoto University
  •  有機ニッケル(III)錯体の創製とそのグアニン特異的認識能の応用Principal Investigator

    • Principal Investigator
      大塚 雅巳
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  がん細胞のアポトーシスを制御する化合物の設計と合成Principal Investigator

    • Principal Investigator
      大塚 雅巳
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      医薬分子機能学
    • Research Institution
      Kyoto University
  •  Action mechanism and molecular design of biologically active enediyne compounds

    • Principal Investigator
      SUGIURA Yukio
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Bioorganic chemistry
    • Research Institution
      KYOTO UNIVERSITY
  •  有機ニッケル(III)錯体の創製とそのグアニン特異的認識能の応用Principal Investigator

    • Principal Investigator
      大塚 雅巳
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  癌遺伝子産物の機能を阻害する化合物の設計と合成Principal Investigator

    • Principal Investigator
      大塚 雅巳
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      医薬分子機能学
    • Research Institution
      Kyoto University
  •  Joint Research on the signal transduction to the nucleus. -from the membrane receptors to the nuclear transcription factors-

    • Principal Investigator
      INOUE Junichiro
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      The University of Tokyo
  •  ブレオマイシン金属錯体に基づく不斉酸化触媒の設計Principal Investigator

    • Principal Investigator
      大塚 雅巳
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Kyoto University
  •  DEVELOPMENT OF METAL COMPLEXES WITH PHYSIOLOGICAL RESPONSE FUNCTION

    • Principal Investigator
      YANO Shigenobu
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Synthetic chemistry
    • Research Institution
      NARA WOMEN'S UNIVERSITY
  •  Chemical Creation of Artificial Restriction Enzyme and Its Application to Genomic Analysis

    • Principal Investigator
      SUGIURA Yukio
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      医薬分子機能学
    • Research Institution
      KYOTO UNIVERSITY
  •  ブレオマイシンの酸素活性化機構に基づく高効率的酸化触媒の設計Principal Investigator

    • Principal Investigator
      大塚 雅巳
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      The University of Tokyo
  •  ブレオマイシンの酸素活性化機能に基づく不斉酸化触媒の設計Principal Investigator

    • Principal Investigator
      大塚 雅巳
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      The University of Tokyo

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation Book Patent

  • [Book] Design and Synthesis of Biotinylated Inositol Phosphates: Application to the Inositol Phosphate-Protein Binding Analysis2013

    • Author(s)
      Kensaku Anraku, Mikako Fujita, Takashi Morii, Yasuo Mori, Yoshinari Okamoto, Masami Otsuka
    • Total Pages
      10
    • Publisher
      Nova Science Publishers, Inc.
    • Data Source
      KAKENHI-PROJECT-24659048
  • [Book] Design and Synthesis of Biotinylated Inositol Phosphates : Application to the Inositol Phosphate-Protein Binding Analysis."Inositol"Ed. By Rochha H, Cardoso M2013

    • Author(s)
      Kensaku Anraku, Mikako Fujita, Takashi Morii, Yasuo Mori, Yoshinari Okamoto, Masami Otsuka
    • Publisher
      Nova Science Publishers, Inc.
    • Data Source
      KAKENHI-PROJECT-24659048
  • [Book] Design and Synthesis of Biotinylated Inositol Phosphates: Application to the Inositol Phosphate-Protein Binding Analysis2013

    • Author(s)
      Kensaku Anraku, Mikako Fujita, Takashi Morii, Yasuo Mori, Yoshinari Okamoto, Masami Otsuka
    • Total Pages
      10
    • Publisher
      Nova Science Publishers, Inc.
    • Data Source
      KAKENHI-PROJECT-23390028
  • [Book] Design and Synthesis of Biotinylated Inositol Phosphates : Application to the Inositol Phosphate-Protein Binding Analysis. "Inositol" (Ed. By Rochha H, Cardoso M)2013

    • Author(s)
      Kensaku Anraku, Mikako Fujita, Takashi Morii, Yasuo Mori, Yoshinari Okamoto, Masami Otsuka
    • Publisher
      Nova Science Publishers, Inc
    • Data Source
      KAKENHI-PROJECT-23390028
  • [Journal Article] Design and Synthesis of an Anthranyl Bridged Optically Active Dinuclear Iron(II)-Ligand and Evaluation of DNA-Cleaving Activity.2021

    • Author(s)
      Ichimaru, Y., Kato, K., Okuno, Y., Yamaguchi, Y., Jin, W., Fujita, M., Otsuka, M., Imai, M., and Kurosaki, H.
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume: 35 Pages: 127782-127782

    • DOI

      10.1016/j.bmcl.2021.127782

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03365
  • [Journal Article] Design and synthesis of novel quinoline/chalcone/1,2,4-triazole hybrids as potent antiproliferative agent targeting EGFR and BRAFV600E kinases2021

    • Author(s)
      Mohassab Aliaa M.、Hassan Heba A.、Abdelhamid Dalia、Gouda Ahmed M.、Youssif Bahaa G.M.、Tateishi Hiroshi、Fujita Mikako、Otsuka Masami、Abdel-Aziz Mohamed
    • Journal Title

      Bioorganic Chemistry

      Volume: 106 Pages: 104510-104510

    • DOI

      10.1016/j.bioorg.2020.104510

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K23802, KAKENHI-PROJECT-20H03365
  • [Journal Article] Discovery of anti-cell migration activity of an anti-HIV heterocyclic compound by identification of its binding protein hnRNP M2021

    • Author(s)
      Kamo Masahiro、Ito Miu、Toma Tsugumasa、Gotoh Haruna、Shimozono Rie、Nakagawa Riko、Koga Ryoko、Monde Kazuaki、Tateishi Hiroshi、Misumi Shogo、Otsuka Masami、Fujita Mikako
    • Journal Title

      Bioorganic Chemistry

      Volume: 107 Pages: 104627-104627

    • DOI

      10.1016/j.bioorg.2021.104627

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K23802, KAKENHI-PROJECT-20H03365
  • [Journal Article] A new series of antileukemic agents: Design, synthesis, in vitro and in silico evaluation of thiazole-based ABL1 kinase inhibitors2021

    • Author(s)
      Zeytun, E., Altintop, M.D., Sever, B., Ozdemir, A., Ellakwa, D.E., Ocak, Z., Ciftci, H.I., Otsuka, M., Fujita, M., and Radwan, M.O.
    • Journal Title

      Anti-Cancer Agents in Medicinal Chemistry

      Volume: 21 Issue: 9 Pages: 1099-1109

    • DOI

      10.2174/1871520620666200824100408

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03365
  • [Journal Article] Interruption of Vif/Elongin C interaction: In silico and experimental elucidation of the underlying molecular mechanism of benzimidazole-based APOBEC3G stabilizers2020

    • Author(s)
      Radwan Mohamed O.、Takaya Daisuke、Koga Ryoko、Iwamaru Kana、Tateishi Hiroshi、Ali Taha F.S.、Takaori-Kondo Akifumi、Otsuka Masami、Honma Teruki、Fujita Mikako
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume: 28 Issue: 8 Pages: 115409-115409

    • DOI

      10.1016/j.bmc.2020.115409

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K23802, KAKENHI-PROJECT-20H03365, KAKENHI-PROJECT-17H03999
  • [Journal Article] The stability of HIV-2 Vpx and Vpr proteins is regulated by the presence or absence of zinc-binding sites and poly-proline motifs with distinct roles2020

    • Author(s)
      Shimagaki Kazunori、Koga Ryoko、Fujino Haruna、Ahagon Ami、Tateishi Hiroshi、Otsuka Masami、Yamaguchi Yoshihiro、Fujita Mikako
    • Journal Title

      Journal of General Virology

      Volume: 101 Issue: 9 Pages: 997-1007

    • DOI

      10.1099/jgv.0.001456

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K23802, KAKENHI-PROJECT-20H03365
  • [Journal Article] Antiproliferative activity of Turkish marine extracts: A purple sponge components induce apoptosis with multiple kinases inhibition2020

    • Author(s)
      Ciftci, H.I., Can, M., Ellakwa, D., Suner, S., Ibrahim, M., Oral, A., Sekeroglu, N., Ozalp, B., Otsuka, M., Fujita, M., Alparslan, M., and Radwan, M.
    • Journal Title

      Investigational New Drugs

      Volume: 38 Issue: 5 Pages: 1326-1333

    • DOI

      10.1007/s10637-020-00911-8

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03365
  • [Journal Article] Structural analysis of TIFA: Insight into TIFA-dependent signal transduction in innate immunity2020

    • Author(s)
      Nakamura Teruya、Hashikawa Chie、Okabe Kohtaro、Yokote Yuya、Chirifu Mami、Toma-Fukai Sachiko、Nakamura Narushi、Matsuo Mihoko、Kamikariya Miho、Okamoto Yoshinari、Gohda Jin、Akiyama Taishin、Semba Kentaro、Ikemizu Shinji、Otsuka Masami、Inoue Jun-ichiro、Yamagata Yuriko
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 5152-5152

    • DOI

      10.1038/s41598-020-61972-6

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06600, KAKENHI-PLANNED-16H06575, KAKENHI-INTERNATIONAL-16K21739, KAKENHI-ORGANIZER-16H06573, KAKENHI-PROJECT-20H03441, KAKENHI-PROJECT-17H03999
  • [Journal Article] HSP70 induction by bleomycin metal core analogs2020

    • Author(s)
      Ali Taha F.S.、Taira Naomi、Iwamaru Kana、Koga Ryoko、Kamo Masahiro、Radwan Mohamed O.、Tateishi Hiroshi、Kurosaki Hiromasa、Abdel-Aziz Mohamed、Abuo-Rahma Gamal El-Din A.A.、Beshr Eman A.M.、Otsuka Masami、Fujita Mikako
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume: 30 Issue: 7 Pages: 127002-127002

    • DOI

      10.1016/j.bmcl.2020.127002

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K23802, KAKENHI-PROJECT-20H03365, KAKENHI-PROJECT-17H03999
  • [Journal Article] Activation of Ligand Reaction on an Iron Complex: H/D Exchange Reaction of a Low-Spin Bis[2-(Pyridylmethylidene)-1-(2-pyridyl)methylamine]iron(II) Complex2020

    • Author(s)
      Imai, M., Kato, K., Yamaguchi, Y., Fujita, M., Otsuka, M, and Kurosaki, H.
    • Journal Title

      Chemical and Pharmaceutical Bulletin

      Volume: 68 Issue: 8 Pages: 713-716

    • DOI

      10.1248/cpb.c20-00383

    • NAID

      130007883294

    • ISSN
      0009-2363, 1347-5223
    • Year and Date
      2020-08-01
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03365
  • [Journal Article] In Vitro and In Silico Evaluation of Anticancer Activity of New Indole-Based 1,3,4-Oxadiazoles as EGFR and COX-2 Inhibitors2020

    • Author(s)
      Belgin Sever, Mehlika Dilek Altintop, Ahmet Ozdemir, Gulsen Akalin Ciftci, Doha E. Ellakwa, Hiroshi Tateishi, Mohamed O. Radwan, Mahmoud A. A. Ibrahim, Masami Otsuka, Mikako Fujita, Halil I. Ciftci and Taha F. S. Ali
    • Journal Title

      Molecules

      Volume: 25 Issue: 21 Pages: 5190-5190

    • DOI

      10.3390/molecules25215190

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K23802, KAKENHI-PROJECT-20H03365
  • [Journal Article] Structure activity study of S-trityl-cysteamine dimethylaminopyridine derivatives as SIRT2 inhibitors: Improvement of SIRT2 binding and inhibition.2020

    • Author(s)
      Radwan, M.O., Ciftci, H.I., Ali, T.F.S., Koga, R., Tateishi, H., Nakata, A., Ito, A., Yoshida, M., Fujita, M., Otsuka, M.
    • Journal Title

      Bioorg. Med. Chem. Lett.

      Volume: 30(19) Issue: 19 Pages: 127458-127458

    • DOI

      10.1016/j.bmcl.2020.127458

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H05640, KAKENHI-PROJECT-19K23802, KAKENHI-PROJECT-20H03365
  • [Journal Article] Serial Femtosecond X-Ray Diffraction of HIV-1 Gag MA-IP6 Microcrystals at Ambient Temperature2019

    • Author(s)
      I Ciftci Halil、G Sierra Raymond、Yoon Chun、Su Zhen、Tateishi Hiroshi、Koga Ryoko、Kotaro Koiwai、Yumoto Fumiaki、Senda Toshiya、Liang Mengling、Wakatsuki Soichi、Otsuka Masami、Fujita Mikako、DeMirci Hasan
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 20 Issue: 7 Pages: 1675-1675

    • DOI

      10.3390/ijms20071675

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08861, KAKENHI-PROJECT-17J11657, KAKENHI-PROJECT-17H03999
  • [Journal Article] Novel p97 / VCP inhibitor induces endoplasmic reticulum stress and apoptosis in both bortezomib‐sensitive and ‐resistant multiple myeloma cells2019

    • Author(s)
      Nishimura Nao、Radwan Mohamed O.、Amano Masayuki、Endo Shinya、Fujii Eri、Hayashi Hironori、Ueno Shikiko、Ueno Niina、Tatetsu Hiro、Hata Hiroyuki、Okamoto Yoshinari、Otsuka Masami、Mitsuya Hiroaki、Matsuoka Masao、Okuno Yutaka
    • Journal Title

      Cancer Science

      Volume: 110 Issue: 10 Pages: 3275-3287

    • DOI

      10.1111/cas.14154

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K17921, KAKENHI-PROJECT-17H03999
  • [Journal Article] Design, synthesis and biological evaluation of a new series of thiazolyl-pyrazolines as dual EGFR and HER2 inhibitors2019

    • Author(s)
      Sever, B., Altintop, M.D., Radwan, M.O., Ozdemir A., Otsuka, M., Fujita, M., and Ciftci, H.I.
    • Journal Title

      European Journal of Medicinal Chemistry

      Volume: 182 Pages: 111648-111648

    • DOI

      10.1016/j.ejmech.2019.111648

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Journal Article] Minimum structural requirements for inhibitors of the zinc finger protein TRAF62019

    • Author(s)
      Radwan Mohamed O.、Koga Ryoko、Hida Tomohiro、Ejima Tomohiko、Kanemaru Yosuke、Tateishi Hiroshi、Okamoto Yoshinari、Inoue Jun-ichiro、Fujita Mikako、Otsuka Masami
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume: 29 Issue: 16 Pages: 2162-2167

    • DOI

      10.1016/j.bmcl.2019.06.050

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K23802, KAKENHI-INTERNATIONAL-16K21739, KAKENHI-ORGANIZER-16H06573, KAKENHI-PLANNED-16H06575, KAKENHI-PROJECT-17H03999
  • [Journal Article] Antiproliferative S-Trityl-l-Cysteine -Derived Compounds as SIRT2 Inhibitors: Repurposing and Solubility Enhancement2019

    • Author(s)
      Radwan Mohamed O.、Ciftci Halil I.、Ali Taha F. S.、Ellakwa Doha E.、Koga Ryoko、Tateishi Hiroshi、Nakata Akiko、Ito Akihiro、Yoshida Minoru、Okamoto Yoshinari、Fujita Mikako、Otsuka Masami
    • Journal Title

      Molecules

      Volume: 24 Issue: 18 Pages: 3295-3295

    • DOI

      10.3390/molecules24183295

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K23802, KAKENHI-PROJECT-19H05640, KAKENHI-PROJECT-26221204, KAKENHI-PROJECT-17H03999
  • [Journal Article] Antileukemic Activity of Twig Components of Caucasian Beech in Turkey2019

    • Author(s)
      Shida Wataru、Tateishi Hiroshi、Tahara Yurika、Fujita Mikako、Husham Majeed Alsaadi Doaa、Watanabe Masato、Koga Ryoko、Radwan Mohamed O.、Ciftci Halil I.、Gezici Sevgi、Kurauchi Yuki、Katsuki Hiroshi、Otsuka Masami、Sugimura Koji、Wada Mikiyo、Sekeroglu Nazim、Watanabe Takashi
    • Journal Title

      Molecules

      Volume: 24 Issue: 21 Pages: 3850-3850

    • DOI

      10.3390/molecules24213850

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07101, KAKENHI-PROJECT-19K22813, KAKENHI-PROJECT-19K23802, KAKENHI-PROJECT-16H04673, KAKENHI-PROJECT-17H03999
  • [Journal Article] A Novel Series of Chlorinated Plastquinone Analogs: Design, Synthesis, and Evaluation of Anticancer Activity2019

    • Author(s)
      Nilufer Bayrak, Hatice Yildirim, Mahmut Yildiz, Mohamed O. Radwan, Masami Otsuka, Mikako Fujita, Halil I. Ciftci, Amac Fatih Tuyun
    • Journal Title

      Chemical Biology & Drug Design

      Volume: 0 Issue: 3 Pages: 1-12

    • DOI

      10.1111/cbdd.13651

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Journal Article] Design, Synthesis and Biological Evaluation of Pentacyclic Triterpene Derivatives: Optimization of Anti-ABL Kinase Activity2019

    • Author(s)
      I. Ciftci Halil、O. Radwan Mohamed、E. Ozturk Safiye、Ulusoy N. Gokce、Sozer Ece、E. Ellakwa Doha、Ocak Zeynep、Can Mustafa、F.S. Ali Taha、I. Abd-Alla Howaida、Yayli Nurettin、Tateishi Hiroshi、Otsuka Masami、Fujita Mikako
    • Journal Title

      Molecules

      Volume: 24 Issue: 19 Pages: 3535-3535

    • DOI

      10.3390/molecules24193535

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K23802, KAKENHI-PROJECT-17H03999
  • [Journal Article] Anti-cancer activity of the cell membrane-permeable phytic acid prodrug2019

    • Author(s)
      Masunaga Takuya、Murao Naoki、Tateishi Hiroshi、Koga Ryoko、Ohsugi Takeo、Otsuka Masami、Fujita Mikako
    • Journal Title

      Bioorganic Chemistry

      Volume: 92 Pages: 103240-103240

    • DOI

      10.1016/j.bioorg.2019.103240

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06036, KAKENHI-PROJECT-19K23802, KAKENHI-PROJECT-17K08861, KAKENHI-PROJECT-17H03999
  • [Journal Article] Neuroprotective effects of a novel carnosine-hydrazide derivative on hippocampal CA1 damage after transient cerebral ischemia2019

    • Author(s)
      Noguchi Kei、Ali Taha F.S.、Miyoshi Junko、Orito Kimihiko、Negoto Tetsuya、Biswas Tanima、Taira Naomi、Koga Ryoko、Okamoto Yoshinari、Fujita Mikako、Otsuka Masami、Morioka Motohiro
    • Journal Title

      European Journal of Medicinal Chemistry

      Volume: 163 Pages: 207-214

    • DOI

      10.1016/j.ejmech.2018.11.060

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08861, KAKENHI-PROJECT-17H03999, KAKENHI-PROJECT-18K08985, KAKENHI-PROJECT-16K10746
  • [Journal Article] Design, synthesis, and biological activity of Plastoquinone analogs as a new class of anticancer agents2019

    • Author(s)
      Nilufer Bayrak, Hatice Yildirim, Mahmut Yildiz, Mohamed O. Radwan, Masami Otsuka, Mikako Fujita, Amac Fatih Tuyun, Halil I. Ciftci
    • Journal Title

      Bioorganic Chemistry

      Volume: 92 Pages: 103255-103255

    • DOI

      10.1016/j.bioorg.2019.103255

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Journal Article] New SIRT2 inhibitors: Histidine-based bleomycin spin-off2019

    • Author(s)
      Ali Taha F.S.、Ciftci Halil I.、Radwan Mohamed O.、Koga Ryoko、Ohsugi Takeo、Okiyama Yoshio、Honma Teruki、Nakata Akiko、Ito Akihiro、Yoshida Minoru、Fujita Mikako、Otsuka Masami
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume: 27 Issue: 9 Pages: 1767-1775

    • DOI

      10.1016/j.bmc.2019.03.003

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08861, KAKENHI-PROJECT-18K06036, KAKENHI-PROJECT-26221204, KAKENHI-PROJECT-17H03999
  • [Journal Article] Blockade of TGF-β/Smad signaling by the small compound HPH-15 ameliorates experimental skin fibrosis2018

    • Author(s)
      Luong Vu Huy、Chino Takenao、Oyama Noritaka、Matsushita Takashi、Sasaki Yoko、Ogura Dai、Niwa Shin-ichiro、Biswas Tanima、Hamasaki Akiyuki、Fujita Mikako、Okamoto Yoshinari、Otsuka Masami、Ihn Hironobu、Hasegawa Minoru
    • Journal Title

      Arthritis Research & Therapy

      Volume: 20 Issue: 1 Pages: 46-46

    • DOI

      10.1186/s13075-018-1534-y

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10165, KAKENHI-PROJECT-17K08861, KAKENHI-PROJECT-17H03999, KAKENHI-PROJECT-16K15143
  • [Journal Article] Design, synthesis and biological evaluation of novel 1,3,4-Thiadiazole derivatives as potential antitumor agents against chronic myelogenous leukemia. Striking effect of nitrothiazole moiety.2018

    • Author(s)
      Altintop, M.D., Ciftci, H.I., Radwan, M.O., Sever, B., Kaplancikli, Z.A., Ali, T.F.S., Koga, R., Fujita, M., Otsuka, M., and Ozdemir, A.
    • Journal Title

      Molecules

      Volume: 23 Issue: 1 Pages: 59-59

    • DOI

      10.3390/molecules23010059

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08861, KAKENHI-PROJECT-16F16111, KAKENHI-PROJECT-17H03999, KAKENHI-PROJECT-16K15143
  • [Journal Article] The First Pentacyclic Triterpenoid Gypsogenin Derivative Exhibiting Anti-ABL1 Kinase and Anti-chronic Myelogenous Leukemia Activities2018

    • Author(s)
      Ciftci, H.I., Ozturk, S.E., Ali, T.F.S., Radwan, M.O., Tateishi, H., Koga, R., Ocak, Z., Can, M., Otsuka, M., and Fujita, M.
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 41 Issue: 4 Pages: 570-574

    • DOI

      10.1248/bpb.b17-00902

    • NAID

      130006602535

    • ISSN
      0918-6158, 1347-5215
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08861, KAKENHI-PROJECT-16F16111, KAKENHI-PROJECT-17H03999, KAKENHI-PROJECT-17J11657, KAKENHI-PROJECT-16K15143
  • [Journal Article] Introduction of H2C2-type zinc-binding residues into HIV-2 Vpr increases its expression level.2018

    • Author(s)
      Koga, R., Yamamoto, M., Ciftci, H.I., Otsuka, M., and Fujita, M.
    • Journal Title

      FEBS Open Bio

      Volume: 1 Issue: 1 Pages: 146-153

    • DOI

      10.1002/2211-5463.12358

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08861, KAKENHI-PROJECT-16F16111, KAKENHI-PROJECT-17H03999, KAKENHI-PROJECT-16K15143
  • [Journal Article] Role of zinc binding site of HIV-2 Vpx prevents instability and dysfunction of the protein2017

    • Author(s)
      Minami Yamamoto, Ryoko Koga, Haruna Fujino, Kazunori Shimagaki, Halil Ibrahim Ciftci, Masahiro Kamo, Hiroshi Tateishi, Masami Otsuka, Mikako Fujita
    • Journal Title

      J. General Virol.

      Volume: 98 Issue: 2 Pages: 275-283

    • DOI

      10.1099/jgv.0.000701

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16F16111, KAKENHI-PROJECT-16K15143, KAKENHI-PROJECT-17H03999
  • [Journal Article] Synthesis, Computational Study, and Evaluation of in vitro Antimicrobial, Antibiofilm, and Anticancer Activities of New Sulfanyl Aminonaphthoquinone Derivatives2017

    • Author(s)
      Nilufer Bayrak, Hatice Yildirim, Amac Fatih Tuyun, Emel Mataraci Kara, Berna Ozbek Celik, Girish Kumar Gupta, Halil I. Ciftci, Mikako Fujita, Masami Otsuka, Hamid R. Nasiri
    • Journal Title

      Letters in Drug Design & Discovery,

      Volume: 14 Issue: 6 Pages: 647-661

    • DOI

      10.2174/157018081406170606155530

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16F16111, KAKENHI-PROJECT-16K15143, KAKENHI-PROJECT-17H03999
  • [Journal Article] Marine Inspired 2-(5-Halo-1H-indol-3-yl)-N,N-Dimethylethanamines As Modulators of Serotonin Receptors: An Example Illustrating the Power of Bromine as part of the Uniquely Marine Chemical Space2017

    • Author(s)
      Mohamed A. Ibrahim, Abir T. El-Alfy, Kelly Ezel, Mohamed O. Radwan, Abbas G. Shilabin, Anna J. Kochanowska-Karamyan, Howaida I. Abd-Alla, Masami Otsuka, Mark T. Hama
    • Journal Title

      Marine Drugs

      Volume: 15 Issue: 8 Pages: 248-248

    • DOI

      10.3390/md15080248

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15143, KAKENHI-PROJECT-17H03999
  • [Journal Article] Zinc binding site of HIV-2 Vpx prevents instability and dysfunction of the protein.2017

    • Author(s)
      3.Yamamoto M, Koga R, Fujino H, Shimagaki K, Ciftci H.I, Kamo M, Tateishi H, Otsuka M and Fujita M.
    • Journal Title

      Journal of General Virology

      Volume: 98 Pages: 275-283

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16F16111
  • [Journal Article] A clue to unprecedented strategy to HIV eradication: “Lock-in and apoptosis”.2017

    • Author(s)
      Tateishi, H., Monde, K., Anraku, K., Koga, R., Hayashi, Y., Ciftci, H.I., DeMirci, H., Higashi, T., Motoyama, K, Arima, H., Otsuka, M., and Fujita, M.
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 8957-8957

    • DOI

      10.1038/s41598-017-09129-w

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08861, KAKENHI-PROJECT-16F16111, KAKENHI-PROJECT-17J11657, KAKENHI-PROJECT-16K15143, KAKENHI-PROJECT-17H03999
  • [Journal Article] A novel inhibitor of farnesyltransferase with a zinc site recognition moiety and a farnesyl group.2017

    • Author(s)
      Tanaka, A., Radwan, M.O., Hamasaki, A., Ejima, A., Obata, E., Koga, R., Tateishi, H., Okamoto, Y., Fujita, M., Nakao, M., Umezawa, K., Tamanoi, F., and Otsuka, M.
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume: 27 Issue: 16 Pages: 3862-3866

    • DOI

      10.1016/j.bmcl.2017.06.047

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08861, KAKENHI-PROJECT-15H04707, KAKENHI-PROJECT-17J11657, KAKENHI-PROJECT-16K15143, KAKENHI-PROJECT-17H03999
  • [Journal Article] A dithiol compound binds to the zinc finger protein TRAF6 and suppresses its ubiquitination.2017

    • Author(s)
      Koga, R., Radwan, M.O., Ejima, T., Kanemaru, Y., Tateishi, H., Ali, T.F.S., Ciftci, H.I., Shibata, Y., Taguchi, Y., Inoue, J., Otsuka, M., and Fujita, M.
    • Journal Title

      ChemMedChem

      Volume: 12 Issue: 23 Pages: 1935-1941

    • DOI

      10.1002/cmdc.201700399

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08861, KAKENHI-PROJECT-17K10999, KAKENHI-PLANNED-16H06575, KAKENHI-PROJECT-16F16111, KAKENHI-PROJECT-17J11657, KAKENHI-PROJECT-16K15143, KAKENHI-PROJECT-17H03999
  • [Journal Article] Zinc-mediated binding of a low-molecular-weight stabilizer of the host anti-viral factor apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3G2016

    • Author(s)
      Radwan, Mohamed O.; Sonoda, Sachiko; Ejima, Tomohiko; Tanaka, Ayumi; Koga, Ryoko; Okamoto, Yoshinari; Fujita, Mikako; Otsuka, Masami
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume: 24 Issue: 18 Pages: 4398-4405

    • DOI

      10.1016/j.bmc.2016.07.030

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26460148, KAKENHI-PROJECT-16K15143
  • [Journal Article] Synthesis of the biotinylated anti-HIV compound BMMP and the target identification study.2016

    • Author(s)
      Kamo M, Tateishi H, Koga R, Okamoto Y, Otsuka M, Fujita M.
    • Journal Title

      Bioorg. Med. Chem.

      Volume: 26 Issue: 1 Pages: 43-45

    • DOI

      10.1016/j.bmcl.2015.11.036

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460570, KAKENHI-PROJECT-26460148, KAKENHI-PROJECT-16K15143
  • [Journal Article] Mutational analysis of HIV-2Vpx shows that proline residue 109 in the poly-proline motif regulates degradation of SAMHD12015

    • Author(s)
      Halil Ibrahim Ciftci, Haruna Fujino, Ryoko Koga, Minami Yamamoto, Sogo Kawamura, Hiroshi Tateishi, Yasumasa Iwatani, Masami Otsuka, Mikako Fujita
    • Journal Title

      FEBS Letters

      Volume: 589 (13) Pages: 1505-1514

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26670058
  • [Journal Article] Novel metal chelating molecules with anticancer activity. Striking effect of the imidazole substitution of the histidine-pyridine-histidine system2015

    • Author(s)
      Ali, Taha F. S.; Iwamaru, Kana; Ciftci, Halil Ibrahim; Koga, Ryoko; Matsumoto, Masahiro; Oba, Yasunori; Kurosaki, Hiromasa; Fujita, Mikako; Okamoto, Yoshinari; Otsuka, Masami et. al.
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume: 23 Issue: 17 Pages: 5476-5482

    • DOI

      10.1016/j.bmc.2015.07.044

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460148, KAKENHI-PROJECT-26462186, KAKENHI-PROJECT-25460570, KAKENHI-PROJECT-25462268, KAKENHI-PROJECT-26670058
  • [Journal Article] L-Histidyl-glycyl-glycyl-L-histidine. Amino-acid structuring of the bleomycin-type pentadentate metal-binding environment capable of efficient double-strand cleavage of plasmid DNA2015

    • Author(s)
      Ida, Satomi; Iwamaru, Kana; Fujita, Mikako; Okamoto, Yoshinari; Kudo, Yuri; Kurosaki, Hiromasa; Otsuka, Masami
    • Journal Title

      Bioorganic Chemistry

      Volume: 62 Pages: 8-14

    • DOI

      10.1016/j.bioorg.2015.06.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26460148, KAKENHI-PROJECT-26670058
  • [Journal Article] Synthesis and Evaluation of New Pyrazoline Derivatives as Potential Anticancer Agents.2015

    • Author(s)
      Karabacak M, Altintop MD, Ciftci H, Koga R, Otsuka M, Fujita M, Ozdemir A.
    • Journal Title

      Molecules

      Volume: 20 Issue: 10 Pages: 19066-19084

    • DOI

      10.3390/molecules201019066

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460570, KAKENHI-PROJECT-26670058
  • [Journal Article] Design and synthesis of lipid-coupled inositol 1, 2, 3, 4, 5, 6-hexakisphosphate derivatives exhibiting high-affinity binding for HIV-1 MA domain2014

    • Author(s)
      Hiroshi Tateishi, Kensaku Anraku, Ryoko Koga, Yoshinari Okamoto, Mikako Fujita, Masami Otsuka
    • Journal Title

      Organic & Biomolecular Chemistry

      Volume: (First published online) Issue: 27 Pages: 5006-5022

    • DOI

      10.1039/c4ob00350k

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390028, KAKENHI-PROJECT-24659048, KAKENHI-PROJECT-26460148, KAKENHI-PROJECT-26670058
  • [Journal Article] Poly-proline motif in HIV-2 Vpx is critical for its efficient translation2014

    • Author(s)
      Ariko Miyake, Mikako Fujita, Haruna Fujino, Ryoko Koga, Sogo Kawamura, Masami Otsuka, Hirotaka Ode, Yasumasa Iwatani, Yosuke Sakai, Naoya Doi, Masako Nomaguchi, Akio Adachi, Yasuyuki Miyazaki
    • Journal Title

      Journal of General Virology

      Volume: 95 Issue: 1 Pages: 179-189

    • DOI

      10.1099/vir.0.057364-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390028, KAKENHI-PROJECT-24590568, KAKENHI-PROJECT-24659048, KAKENHI-PROJECT-24659208, KAKENHI-PROJECT-24790443, KAKENHI-PROJECT-26670058
  • [Journal Article] Inhibitors of Transcription factor Nuclear Factor-kappa Beta (NF-κB)-DNA binding2013

    • Author(s)
      Rakesh Kumar Sharma, Masami Otsuka, Garima Gaba, Shilpa Mehta
    • Journal Title

      RSC Advances

      Volume: 3 Pages: 1282-1296

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659048
  • [Journal Article] Inhibitors of Transcription factor Nuclear Factor-kappa Beta (NF-κB)-DNA binding2013

    • Author(s)
      Rakesh Kumar Sharma, Masami Otsuka, Garima Gaba, Shilpa Mehta
    • Journal Title

      RSC Advances

      Volume: 3 Pages: 1282-1296

    • Data Source
      KAKENHI-PROJECT-23390028
  • [Journal Article] Effect of the STAT3 inhibitor STX-0119 on the proliferation of cancer stem-like cells derived from recurrent glioblastoma2013

    • Author(s)
      Tadashi Ashizawa, Haruo Miyata, Akira Iizuka, Masaru Komiyama, Chie Oshita, Akiko Kume, Masahiro Nogami, Mika Yagoto, Ichiro Ito, Takuma Oishi, Reiko Watanabe, Koichi Mitsuya, Kenji Matsuno, Toshio Furuya, Tadashi Okawara, Masami Otsuka, Naohisa Ogo, Akira Asai, Yoko Nakasu, Ken Yamaguchi Yasuto Akiyama
    • Journal Title

      International Journal of Oncology

      Volume: 43 Issue: 1 Pages: 219-227

    • DOI

      10.3892/ijo.2013.1916

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390028, KAKENHI-PROJECT-23510281, KAKENHI-PROJECT-24501362, KAKENHI-PROJECT-24659048
  • [Journal Article] A versatile intermediate for the systematic synthesis of all regioisomers of myo-inositol phosphates2012

    • Author(s)
      Masuda Takashi, Anraku Kensaku, Kimura Mitsuhiro, Sato Kaori, Okamoto Yoshinari, Otsuka Masami
    • Journal Title

      Synthesis

      Volume: 44 (6) Pages: 909-919

    • NAID

      120005368275

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590131
  • [Journal Article] Identification of a unique nsaid, fluoro-loxoprofen with gastroprotective activity2012

    • Author(s)
      Shintaro Suemasu, Naoki Yamakawa, Tomoaki Ishihara, Teita Asano, Kayoko Tahara, Ken-ichiro Tanaka, Hirofumi Matsui, Yoshinari Okamoto, Masami Otsuka, Koji Takeuchi, Hidekazu Suzuki, Tohru Mizushima
    • Journal Title

      Biochemical Pharmacology

      Volume: 84 (11) Pages: 1470-1481

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590131
  • [Journal Article] A versatile intermediate for the systematic synthesis of all regioisomers of myo-inositol phosphates.2012

    • Author(s)
      Masuda Takashi, Anraku Kensaku, Kimura Mitsuhiro, Sato Kaori, Okamoto Yoshinari, Otsuka Masami
    • Journal Title

      Synthesis

      Volume: 44(6) Pages: 909-919

    • NAID

      120005368275

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590131
  • [Journal Article] A Versatile Intermediate for the Systematic Synthesis of All Regioisomers of myo-Inositol Phosphates2012

    • Author(s)
      Takashi Masuda, Kensaku Anraku, Mitsuhiro Kimura, Kaori Sato, Yoshinari Okamoto, Masami Otsuka
    • Journal Title

      Synthesis

      Volume: 44(6) Issue: 06 Pages: 909-919

    • DOI

      10.1055/s-0031-1289730

    • NAID

      120005368275

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390028, KAKENHI-PROJECT-24659048
  • [Journal Article] Identification of a unique nsaid, fluoro-loxoprofen with gastroprotective activity.2012

    • Author(s)
      Suemasu S., et al.
    • Journal Title

      Biochem Pharmacol.

      Volume: 84 Issue: 11 Pages: 1470-1481

    • DOI

      10.1016/j.bcp.2012.09.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J06922, KAKENHI-PROJECT-22300169, KAKENHI-PROJECT-23390028, KAKENHI-PROJECT-24659037, KAKENHI-PROJECT-24659048, KAKENHI-PROJECT-24659103, KAKENHI-PROJECT-24790077
  • [Journal Article] Synthesis and biological evaluation of derivatives of 2-{2-fluor)-4-[(2-oxocyclopentyl) methyl] phenyl } propanoic acid : Non-steroidal Anti-inflammatory Drugs with Low Gastric Ulcerogenic Activity2012

    • Author(s)
      NAOKI YAMAKAWA, Shintaro Suemasu, Yoshinari Okamoto, Ken-ichiro Tanaka, Tomoaki Ishihara, Teita Asano, Keishi Miyata, Masami Otsuka, Tohru Mizushima
    • Journal Title

      Journal of Medicinal Chemistry

      Volume: (in press) Issue: 11 Pages: 3299-3311

    • DOI

      10.1021/jm300049g

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-10J04305, KAKENHI-PROJECT-11J06922, KAKENHI-PROJECT-22790111, KAKENHI-PROJECT-23390028, KAKENHI-PROJECT-24659048
  • [Journal Article] SAMHD1-dependent and-independent functions of HIV-2/SIV Vpx protein2012

    • Author(s)
      Mikako Fujita, Masako Nomaguchi, Akio Adachi, Masami Otsuka
    • Journal Title

      Frontiers in Microbiology

      Volume: Vol3, Article297 Pages: 1-7

    • DOI

      10.3389/fmicb.2012.00297

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390028, KAKENHI-PROJECT-24659048, KAKENHI-PROJECT-24659208
  • [Journal Article] An artificial copper complex incorporating a cell-penetrating peptide inhibits NF-κB activation2011

    • Author(s)
      Kanemaru Y, Momiki Y, Matsuura S, Horikawa T, Gohda J, Inoue J, Okamoto Y, Fujita M, and Otsuka M.
    • Journal Title

      Chemical & Pharmaceutical Bulletin

      Volume: 59 Pages: 1555-1558

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590131
  • [Journal Article] Design and synthesis of biotinylated inositol 1, 3, 4, 5-tetrakisphosphate targeting Grp1 Pleckstrin Homogy domain2011

    • Author(s)
      Kensaku Anraku, Teruhiko Inoue, Kenji Sugimoto, Kota Kudo, Yoshinari Okamoto, Takashi Morii, Yasuo Mori, Masami Otsuka
    • Journal Title

      Bioorg. Med. Chem.

      Volume: 19 Pages: 6833-6841

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659024
  • [Journal Article] Synthesis and biological evaluation of loxoprofen derivatives2011

    • Author(s)
      Yamakawa N, Suemasu S, Matoyama M, Tanaka K, Katsu T, Miyata K, Okamoto Y, Otsuka M, and Mizushima T
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume: 19 (11) Pages: 3299-3311

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590131
  • [Journal Article] An artificial copper complex incorporating a cell-penetrating peptide inhibits NF-κB activation2011

    • Author(s)
      Kanemaru Y, Momiki Y, Matsuura S, Horikawa T, Gohda J, Inoue J, Okamoto Y, Fujita M, and Otsuka M
    • Journal Title

      Chemical & Pharmaceutical Bulletin

      Volume: 59 (12) Pages: 1555-1558

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590131
  • [Journal Article] An anti-HIV-1 compound that increase steady-state expression of apoplipoprotein B mRNA-editing Enzyme-catalytic polypep-tide-like 3G2011

    • Author(s)
      Tomohiko Ejima, Mayuko Hirota, Tamio Mizukami, Masami Otsuka, Mikako Fujita
    • Journal Title

      Int. J. Mol. Med.

      Volume: 28 Pages: 613-616

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659024
  • [Journal Article] Design and synthesis of biotinylated inositol 1,3,4,5-tetrakisphosphate targeting Grp1 pleckstrin homology domain.2011

    • Author(s)
      Anraku K, Inoue T, Sugimoto K, Kudo K, Okamoto Y, Morii T, Mori Y, and Otsuka M.
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume: 19 Pages: 6833-6841

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590131
  • [Journal Article] An Artificial Copper Complex Incorporating a Cell-Penetrating Peptide Inhibits Nuclear Factor-.KAPPA.B (NF-.KAPPA.B) Activation2011

    • Author(s)
      Yosuke Kanemaru, Yumi Momiki, Saori Matsuura, Tatsufumi Horikawa, Jin Gohda, Jun-ichiro Inoue, Yoshinari Okamoto, Mikako Fujita, Masami Otsuka
    • Journal Title

      Chemical and Pharmaceutical Bulletin

      Volume: 59 Issue: 12 Pages: 1555-1558

    • DOI

      10.1248/cpb.59.1555

    • NAID

      130001852132

    • ISSN
      0009-2363, 1347-5223
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390028
  • [Journal Article] An Artificial Copper Complex Incorporating a Cell-penetrating Peptide Inhibits NF-B Activation2011

    • Author(s)
      Yosuke Kanemaru, Yumi Momiki, Saori Matsuura, Tatsufumi Horikawa, Jin Gohda, Jun-ichiro Inoue, Yoshinari Okamoto, Mikako Fujita, Masami Otsuka
    • Journal Title

      Chem. Pharm. Bull.

      Volume: 59 Pages: 1555-1558

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659024
  • [Journal Article] An anti-HIV-1 compound that increase steady-state expression of apoplipoprotein B mRNA-editing Enzyme-catalytic polypeptide-like 3G2011

    • Author(s)
      Tomohiko Ejima, Mayuko Hirota, Tamio Mizukami, Masami Otsuka, Mikako Fujita
    • Journal Title

      Int. J. Mol. Med

      Volume: 28(4) Pages: 613-616

    • DOI

      10.3892/ijmm.2011.737

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390028
  • [Journal Article] Synthesis and biological evaluation of loxoprofen derivatives2011

    • Author(s)
      Yamakawa N, Suemasu S, Matoyama M, Tanaka K, Katsu T, Miyata K, Okamoto Y, Otsuka M, and Mizushima T.
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume: 19 Pages: 3299-3311

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590131
  • [Journal Article] Design and synthesis of biotinylated inositol 1,3,4,5-tetrakisphosphate targeting Grp1 pleckstrin homology domain2011

    • Author(s)
      Anraku K, Inoue T, Sugimoto K, Kudo K, Okamoto Y, Morii T, Mori Y, and Otsuka M
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume: 19 Pages: 6833-6841

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590131
  • [Journal Article] Design and synthesis of biotinylated inositol 1,3,4,5-tetrakisphosphate targeting Grp1 pleckstrin homology domain2011

    • Author(s)
      Anraku, K.; Inoue, T.; Sugimoto, K.; Kudo, K.; Okamoto, Y.; Morii, T.; Mori, Y.; Otsuka, M.
    • Journal Title

      Bioorg.Med.Chem.

      Volume: 19 Issue: 22 Pages: 6833-6841

    • DOI

      10.1016/j.bmc.2011.09.035

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-22121510, KAKENHI-PROJECT-23390028
  • [Journal Article] Highly Sensitive Analysis of the Interaction between HIV-1 Gag and Phosphoinositide Derivatives Based on Surface Plasmon Resonance.2010

    • Author(s)
      Kensaku Anraku, Ryota Fukuda, Nobutoki Takamune, Shogo Misumi, Yoshinari Okamoto, Masami Otsuka, Mikako Fujita.
    • Journal Title

      Biochemistry 49(25)

      Pages: 5109-5116

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390033
  • [Journal Article] Low Direct Cytotoxicity of Loxoprofen on Gastric Mucosal Cells.2010

    • Author(s)
      Naoki Yamakawa, Shintaro Suemasu, Ayumi Kimoto, Yasuhiro Arai, Tomoaki Ishihara, Kazumi Yokomizo, Yoshinari Okamoto, Masami Otsuka, Ken-ichiro Tanaka, Tohru Mizushima.
    • Journal Title

      Biol.Pharm.Bull. 33(3)

      Pages: 398-403

    • NAID

      130000248088

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390033
  • [Journal Article] Evaluation of allergenicity of constituents of myoga using the murine local lymph node assay (LLNA)2010

    • Author(s)
      Qingjun Wei, Koichi Harada, Keiko Minamoto, Chang-Nian Wei, Yoshinari Okamoto, Masami Otsuka, Atsushi Ueda
    • Journal Title

      J. Immunopathology and pharmacology Vol.23

      Pages: 463-470

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590104
  • [Journal Article] Identification of a New Series of STAT3 Inhibitors by Virtual Screening.2010

    • Author(s)
      Kenji Matsuno, Yoshiaki Masuda, Yutaka Uehara, Hiroshi Sato, Ayumu Muroya, Osamu Takahashi, Takane Yokotagawa, Toshio Furuya, Tadashi Okawara, Masami Otsuka, Naohisa Ogo, Tadashi Ashizawa, Chie Oshita, Sachiko Tai, Hidee Ishii, Yasuto Akiyama, Akira Asai.
    • Journal Title

      ACS Med.Chem.Lett. 1(8)

      Pages: 371-375

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390033
  • [Journal Article] Properties and synthesis of 2-{2-Fluoro (or Bromo)-4-[(2-oxocyclopenty1)methyl]phenyl}propanoic acid : Non-steroidal Anti-inflammatory Drugs with Low Membrane Permeabilizing and Gastric Lesion-producing Activities.2010

    • Author(s)
      Naoki Yamakawa, Shintaro Suemasu, Masaaki Matoyama, Ayumi Kimoto, Miho Takeda, Ken-ichiro Tanaka, Tomoaki Ishihara, Takashi Katsu, Yoshinari Okamoto, Masami Otsuka, Tohru Mizushima.
    • Journal Title

      J.Med.Chem. 53(21)

      Pages: 7879-7882

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390033
  • [Journal Article] Multifaceted activity of HIV Vpr/Vpx proteins : the current view of their virological functions.2010

    • Author(s)
      Mikako Fujita, Masami Otsuka, Masako Nomaguchi, Akio Adachi.
    • Journal Title

      Reviews in Medical Virology 20

      Pages: 68-76

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390033
  • [Journal Article] Low direct cytotoxicity of loxoprofen on gastric mucosal cells2010

    • Author(s)
      Naoki Yamakawa, Shintaro Suemasu, Ayumi Kimoto, Yasuhiro Arai, Tomoaki Ishihara, Kazumi Yokomizo, Yoshinari Okamoto, Masami Otsuka
    • Journal Title

      Ken-ichiro Tanaka and Tohru Mizushima, Biol. Pharm. Bull. Vol.33

      Pages: 398-403

    • NAID

      130000248088

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590104
  • [Journal Article] Properties and Synthesis of 2-{2-Fluoro (or Bromo)-4-[(2-oxocyclo pentyl)methyl]phenyl}propanoic acid : Nonsteroidal Antiinflmmatory Drugs withLow Membrane Permeabiliz- ing and Gastric Lesion-Producing Activities2010

    • Author(s)
      Naoki Yamakawa, Shintaro Suemasu, Masaaki Matoyama, Ayumi Kimoto, Miho Takeda, Ken-ichiro Tanaka, Tomoaki Ishihara, Takashi Katsu, Yoshinari Okamoto, Masami Otsuka, Tohru Mizushima
    • Journal Title

      J. Med. Chem. Vol.53

      Pages: 7879-7882

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590104
  • [Journal Article] Evaluation of allergenicity of constituents of myoga using the murine local lymph node assay (LLNA).2010

    • Author(s)
      Qingjun Wei, Koichi Harada, Keiko Minamoto, Chang-Nian Wei, Yoshinari Okamoto, Masami Otsuka, Atsushi Ueda.
    • Journal Title

      Int.J.Immunopathology and Pharmacology 23(2)

      Pages: 463-470

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390033
  • [Journal Article] Multifaceted activity of HIV Vpr/Vpx proteins : the current view of their virological functions2010

    • Author(s)
      Mikako Fujita, Masami Otsuka, Masako Nomaguchi, Akio Adachi
    • Journal Title

      Reviews in Medical Virology

      Volume: 20 Pages: 68-76

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659024
  • [Journal Article] Highly Sensitive Analysis of the Interaction between HIV-1 Gag and Phosphoinositide Derivatives Based on Surface Plasmon Resonance2010

    • Author(s)
      Kensaku Anraku, Ryota Fukuda, Nobutoki Takamune, Shogo Misumi, Yoshinari Okamoto, Masami Otsuka, Mikako Fujita
    • Journal Title

      Biochemistry Vol.49

      Pages: 5109-5116

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590104
  • [Journal Article] Highly Sensitive Analysis of the Interaction between HIV-1 Gag and Phosphoinositide Derivatives Based on Surface Plasmon Resonance2010

    • Author(s)
      Kensaku Anraku, Ryota Fukuda, Nobutoki Takamune, Shogo Misumi, Yoshinari Okamoto, Masami Otsuka, Mikako Fujita
    • Journal Title

      Biochemistry

      Volume: 49 Pages: 5109-5116

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659024
  • [Journal Article] Synthesis of Prostaglandin E1 Phosphate Derivatives and Their Encapsulation in Biodegradable Nanoparticles.2009

    • Author(s)
      Miho Takeda, Taishi Maeda, Tsutomu Ishihara, Haruka Sakamoto, Kanae Yuki, Naoko Takasaki, Fumihiro Nishimura, Takeshi Yamashita, Ken-ichiro Tanaka, Mitsuko Takenaga, Rie Igarashi, Megumu Higaki, Naoki Yamakawa, Yoshinari Okamoto, Hisao Ogawa, Masami Otsuka, Yutaka Mizushima, Tohru Mizushima.
    • Journal Title

      Pharmaceutical Research 26(7)

      Pages: 1792-1800

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390033
  • [Journal Article] Accerelated blood clearance phenomenon upon repeated injection of PEG-modified PLA-nanoparticles2009

    • Author(s)
      Tsutomu Ishihara, Miho Takeda, Haruka Sakamoto, Ayumi Kimoto, Chisa Kobayashi, Naoko Takasaki, Kanae Yuki, Ken-ichiro Tanaka, Mitsuko Takenaga, Rie Igarashi, Taishi Maeda, Naoki Yamakawa, Yoshinari Okamoto, Masami Otsuka, Tatsuhiro Ishida, Hiroshi Kiwada, Yutaka Mizushima, Tohru Mizushima
    • Journal Title

      Pharmaceut. Res. Vol.26

      Pages: 2270-2279

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590104
  • [Journal Article] Accerelated blood clearance phenomenon upon repeated injection of PEG-modified PLA-nanoparticles.2009

    • Author(s)
      Tsutomu Ishihara, Miho Takeda, Haruka Sakamoto, Ayumi Kimoto, Chisa Kobayashi, Naoko Takasaki, Kanae Yuki, Ken-ichiro Tanaka, Mitsuko Takenaga, Rie Igarashi, Taishi Maeda, Naoki Yamakawa, Yoshinari Okamoto, Masami Otsuka, atsuhiro Ishida, Hiroshi Kiwada, Yutaka Mizushima, Tohru Mizushima.
    • Journal Title

      Pharmaceutical Research 26(10)

      Pages: 2270-2279

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390033
  • [Journal Article] Synthesis of prostagrandin E1 phosphate derivatives and their encapsulation in biodegradable nanoparticle2009

    • Author(s)
      Miho Takeda, Taishi Maeda, Tsutomu Ishihara, Haruka Sakamoto, Kanae Yuki, Naoko Takasaki, Fumihiro Nishimura, Takeshi Yamashita, Ken-ichiro Tanaka, Mitsuko Takenaga, Rie Igarashi, Megumu Higaki, Naoki Yamakawa, Yoshinari Okamoto, Hisao Ogawa, Masami Otsuka, Yutaka Mizushima, Tohru Mizushima
    • Journal Title

      Pharmaceut. Res. Vol.26

      Pages: 1792-1800

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590104
  • [Journal Article] Vpx is critical for the reversetranscription of human immunodeficiency virus type 2 genome in macrophages.2008

    • Author(s)
      Mikako Fujita, Masami Otsuka, Masami Miyoshi, Boonruang Khamsri, Masako Nomaguchi, Akio Adachi.
    • Journal Title

      J.Virology 82(15)

      Pages: 7752-7756

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390033
  • [Journal Article] Synthesis of the indole core structure of conophylline.2008

    • Author(s)
      Shin Ando, Yoshinari Okamoto, Kazuo Umezawa, Masami Otsuka.
    • Journal Title

      J.Heterocyclic Chem. 45

      Pages: 1803-1808

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390033
  • [Journal Article] Functional region mapping of HIV-2 Vpx protein.2008

    • Author(s)
      Mikako Fujita, Masami Otsuka, Masako Nomaguchi, Akio Adachi.
    • Journal Title

      Microbes and Infection 10(12-13)

      Pages: 1387-1392

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390033
  • [Journal Article] Antiviral activities against herpes simplex virus type 1 by HPH derivatives and their structure-activity relationships.2008

    • Author(s)
      Tetsuji Hosono, Kazumi Yokomizo, Akiyuki Hamasaki, Yoshinari Okamoto, Tadashi Okawara, Masami Otsuka, Ryozaburo Mukai, Keitarou Suzuki.
    • Journal Title

      Bioorg.Med.Chem.Lett. 18(1)

      Pages: 371-374

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390033
  • [Journal Article] Design and synthesis of biotynylated inositol phosphate relevant to the biotin-avidin techniques2008

    • Author(s)
      Kensaku Anraku, Teruhiko Inoue, Kenji Sugimoto, Takashi Morii, Yasuo Mori, Yoshinari Okamoto, Masami Otsuka
    • Journal Title

      Org. Biomol. Chem. Vol.6

      Pages: 1822-1830

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590104
  • [Journal Article] Antiviral activities against herpes simplex virus type 1 by HPH derivatives and their structure-activity relationships2008

    • Author(s)
      Tetsuji Hosono, Kazumi Yokomizo, Akiyuki Hamasaki, Yoshinari Okamoto, Tadashi Okawara, Masami Otsuka, Ryozaburo Mukai, Keitaro Suzuki
    • Journal Title

      Bioorg. Med. Chem. Lett. Vol.18

      Pages: 371-374

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590104
  • [Journal Article] Design and synthesis of biotinylated inositol phosphates relevant to the biotin?avidin techniques.2008

    • Author(s)
      Kensaku Anraku, Teruhiko Inoue, Kenji Sugimoto, Takashi Morii, Yasuo Mori, Yoshinari Okamoto, Masami Otsuka.
    • Journal Title

      Org.Biomol.Chem. 6

      Pages: 1822-1830

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390033
  • [Journal Article] Synthesis of the indole core structures of conophylline2008

    • Author(s)
      Shin Ando, Yoshinari Okamoto, Kazuo Umezawa, Masami Otsuka
    • Journal Title

      J. Heterocycl. Chem. Vol.45

      Pages: 1803-1808

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590104
  • [Patent] 線維症治療薬2019

    • Inventor(s)
      倉原琳、尹浩信、大塚雅巳
    • Industrial Property Rights Holder
      サイエンスファーム株式会社
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Patent] フィチン酸エステル誘導体2018

    • Inventor(s)
      藤田美歌子、大塚雅巳、大杉剛生、立石大、村尾直樹、増永拓弥
    • Industrial Property Rights Holder
      熊本大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Patent] フィチン酸エステル誘導体2018

    • Inventor(s)
      藤田美歌子、大塚雅巳、立石大、村尾直樹、増永拓弥、大杉剛生
    • Industrial Property Rights Holder
      サイエンスファーム株式会社
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-17K08861
  • [Patent] 179.ピリジンおよびベンゼン誘導体2017

    • Inventor(s)
      178.大塚雅巳、丹羽眞一郎、小倉大
    • Industrial Property Rights Holder
      178.大塚雅巳、丹羽眞一郎、小倉大
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Patent] APOBEC3発現向上剤及び抗HIV剤2010

    • Inventor(s)
      藤田美歌子、大塚雅巳、江島智彦
    • Industrial Property Rights Holder
      国立大学法人熊本大学
    • Filing Date
      2010-04-28
    • Data Source
      KAKENHI-PROJECT-20390033
  • [Patent] APOBEC3発現向上剤及び抗HIV剤2010

    • Inventor(s)
      藤田美歌子、大塚雅巳、江島智彦
    • Industrial Property Rights Holder
      熊本大学
    • Filing Date
      2010-04-28
    • Data Source
      KAKENHI-PROJECT-22659024
  • [Patent] ロキソプロフェン誘導体及びそれを含有する医薬2009

    • Inventor(s)
      水島徹、大塚雅巳、岡本良成、山川直樹
    • Industrial Property Rights Holder
      国立大学法人熊本大学、株式会社LTTバイオファーマ
    • Industrial Property Number
      2009-043801
    • Filing Date
      2009-02-26
    • Data Source
      KAKENHI-PROJECT-20390033
  • [Patent] ロキソプロフェン誘導体及びそれを含有する医薬2009

    • Inventor(s)
      水島徹,大塚雅巳,岡本良成,山川直樹
    • Industrial Property Rights Holder
      国立大学法人熊本大学,株式会社LTTバイオファーマ
    • Industrial Property Number
      2009-043801
    • Filing Date
      2009-02-26
    • Data Source
      KAKENHI-PROJECT-20590104
  • [Presentation] フィチン酸プロドラッグ体の合成と機能解析2020

    • Author(s)
      増永 拓弥、立石 大、石橋 拓朗、村尾 直樹、古賀 涼子、大杉 剛生、大塚 雅巳、 藤田美歌子
    • Organizer
      日本薬学会第140年会
    • Data Source
      KAKENHI-PROJECT-17K08861
  • [Presentation] 抗HIV活性を持つヘテロ環化合物BMMPの作用機序解明と構造の変換2019

    • Author(s)
      加茂真宏、立石大、岡本良成、三隅将吾、大塚雅巳、藤田美歌子
    • Organizer
      日本薬学会第139年会
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Presentation] カルジオリピンとHIV-1 Gag MAドメインとの結合解析と創薬への展開2019

    • Author(s)
      坂本亜里紗、立石大、門出和精、古賀涼子、小祝孝太郎、湯本史明、田辺幹雄、千田俊哉、三隅将吾、大塚雅巳、藤田美歌子、安楽健作
    • Organizer
      第37回メディシナルケミストリーシンポジウム
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Presentation] Pentacyclic triterpene derivatives with selective anti-proliferative effect against chronic myelogenous leukemia2019

    • Author(s)
      Mohamed O. Radwan, Halil Ciftci, Safiye Emirdag-Ozturk, N. Gokce Ulsoy, Ece Sozer, Nurettin Yayli, Mikeko Fujita, Masami Otsuka
    • Organizer
      The fifth International Symposium on Pharmaceutical and Biomedical Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Presentation] HIV-2 Vpx/Vpr regulates their stability using two motifs2019

    • Author(s)
      Kazunori Shimagaki, Ryoko Koga, Haruna Fujino, Halil Ibrahim Ciftci, Minami Yamamoto, Hiroshi Tateishi, Masami Otsuka, Yoshihiro Yamaguchi, Mikako Fujita
    • Organizer
      The fifth International Mediterranean Symposium on Medicinal and Aromatic Plants
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Presentation] 人工イノシトールリン脂質誘導体を用いた新規HIV-1根絶法の開発2019

    • Author(s)
      立石大、門出和精、安楽健作、古賀涼子、チッフチハリルイブラヒム、小祝孝太郎、湯本史明、千田俊哉、大塚雅巳、藤田美歌子
    • Organizer
      日本ケミカルバイオロジー学会第14回年会
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Presentation] Strategic Design of Drug Core Structure2019

    • Author(s)
      Masami Otsuka
    • Organizer
      Ege University-Kumamoto University-Karadeniz Technical University Collaborative Meeting at Multidisciplinary studies
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Presentation] 細胞膜透過性を向上したIP6誘導体の合成と活性評価2019

    • Author(s)
      増永拓弥、立石大、村尾直樹、古賀涼子、藤田美歌子、大塚雅巳
    • Organizer
      日本薬学会第139年会
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Presentation] 亜鉛結合性低分子化合物によるTRAF6からのシグナル阻害2019

    • Author(s)
      下園理恵、古賀涼子、ラドワン モハメド オスマン、立石大、江島智彦、金丸陽亮、井上純一郎、大塚雅巳、藤田美歌子
    • Organizer
      日本ケミカルバイオロジー学会第14回年会
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Presentation] 抗HIV活性を持つヘテロ環化合物BMMPの作用機序解明と構造の改変2019

    • Author(s)
      加茂 真宏、立石 大、岡本 良成、三隅 将吾、大塚 雅巳、藤田 美歌子
    • Organizer
      日本薬学会第139年会
    • Data Source
      KAKENHI-PROJECT-17K08861
  • [Presentation] 細胞膜透過性を向上したIP6誘導体の合成と活性評価2019

    • Author(s)
      増永 拓弥、立石 大、村尾 直樹、古賀 涼子、藤田 美歌子、大塚 雅巳
    • Organizer
      日本薬学会第139年会
    • Data Source
      KAKENHI-PROJECT-17K08861
  • [Presentation] Strategic Design of Drug Core Structure: A Bleomycin Spinout Story2019

    • Author(s)
      Masami Otsuka
    • Organizer
      The fifth International Symposium on Pharmaceutical and Biomedical Sciences
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Presentation] 創薬を目指したHIV-1 Gag MAドメインとカルジオリピンとの結合解析2018

    • Author(s)
      安楽健作、立石 大、古賀涼子、福田亮太、坂本亜里紗、大塚雅巳、藤田美歌子
    • Organizer
      第32回日本エイズ学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K08861
  • [Presentation] Kinase Inhibitory Activity of Glycyrrhetic Acid2018

    • Author(s)
      Halil I Ciftci, Mohamed O Radwan, Masami Otsuka, Mikako Fujita
    • Organizer
      The 4th International Symposium on Pharmaceutical and Biomedical Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16F16111
  • [Presentation] HIV-2 Vpxは亜鉛結合部位とポリプロリンモチーフにより発現量を上げる2018

    • Author(s)
      島垣和功、古賀涼子、藤野悠那、Halil Ibrahim Ciftci、山本充奈美、大塚雅巳、山口佳宏、藤田美歌子
    • Organizer
      第32回日本エイズ学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Presentation] HNEを標的とした新規脳保護薬2018

    • Author(s)
      Tanima Biswas, Taha Farouk Shehata Ali, 平尚未、古賀涼子、森美晴、岡本良成、藤田美歌子、折戸公彦、野口慶、三好淳子、森岡基浩、大塚雅巳
    • Organizer
      日本薬学会第137年会
    • Data Source
      KAKENHI-PROJECT-17K08861
  • [Presentation] Kinase Inhibitory Activity of Glycyrrhetic Acid.2018

    • Author(s)
      Halil I Ciftci, Mohamed O Radwan, Masami Otsuka, Mikako Fujita
    • Organizer
      The 4th International Symposium on Pharmaceutical and Biomedical Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08861
  • [Presentation] HNEを標的とした新規脳保護薬2018

    • Author(s)
      Tanima Biswas, Taha Farouk Shehata Ali, 平尚未、古賀涼子、森美晴、岡本良成、藤田美歌子、折戸公彦、野口慶、三好淳子、森岡基浩、大塚雅巳
    • Organizer
      日本薬学会第137年会
    • Data Source
      KAKENHI-PROJECT-16K15143
  • [Presentation] HIV根絶を目指した人工イノシトールリン脂質誘導体の開発2018

    • Author(s)
      立石 大、安楽健作、古賀涼子、チッフチ ハリル イブラヒム、大塚雅巳、藤田美歌子
    • Organizer
      日本ケミカルバイオロジー学会第13回年会
    • Data Source
      KAKENHI-PROJECT-17K08861
  • [Presentation] Kinase Inhibitory Activity of Glycyrrhetic Acid2018

    • Author(s)
      Halil I Ciftci, Mohamed O Radwan, Masami Otsuka, Mikako Fujita
    • Organizer
      The 4th International Symposium on Pharmaceutical and Biomedical Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Presentation] Development of a novel method for HIV eradication:“lock-in and apoptosis”2018

    • Author(s)
      Hiroshi Tateishi, Halil Ibrahim Ciftci, Ryoko Koga, Kazuaki Monde, Kensaku Anraku, Kotaro Koiwai, Fumiaki Yumoto, Toshiya Senda, Masami Otsuka, Mikako Fujita
    • Organizer
      Frontiers in Retrovirology Conference 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08861
  • [Presentation] Development of a novel method for HIV eradication: “lock-in and apoptosis”2018

    • Author(s)
      Tateishi, Hiroshi; Ciftci, Halil Ibrahim; Koga, Ryoko; Monde, Kazuaki; Anraku, Kensaku; Koiwai, Kotaro; Yumoto, Fumiaki; Senda, Toshiya; Otsuka, Masami; Fujita, Mikako
    • Organizer
      Frontiers in Retrovirology Conference 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Presentation] HIV根絶を目指した人工イノシトールリン脂質誘導体の開発2018

    • Author(s)
      立石大、安楽健作、古賀涼子、チッフチ ハリル イブラヒム、大塚雅巳、藤田美歌子
    • Organizer
      日本ケミカルバイオロジー学会第13回年会
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Presentation] 抗HIV活性を持つ新規フラーレン誘導体の作用機序解明2018

    • Author(s)
      加茂真宏、安野拓実、高橋恭子、大塚雅巳、大江知之、増野匡彦、藤田美歌子
    • Organizer
      第32回日本エイズ学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K08861
  • [Presentation] 抗HIV活性を持つ新規フラーレン誘導体の作用機序解明2018

    • Author(s)
      加茂真宏、安野拓実、高橋恭子、大塚雅巳、大江知之、増野匡彦、藤田美歌子
    • Organizer
      第32回日本エイズ学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Presentation] Zinc Proteins as Drug Targets2018

    • Author(s)
      Masami Otsuka
    • Organizer
      The 4th International Symposium on Pharmaceutical and Biomedical Sciences
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Presentation] 抗BCR-ABL活性を持つ植物由来五環性トリテルペノイド2018

    • Author(s)
      藤田美歌子、大塚雅巳
    • Organizer
      第22回日本がん分子標的治療学会
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Presentation] HNEを標的とした新規脳保護薬2018

    • Author(s)
      Tanima Biswas, Taha Farouk Shehata Ali, 平尚未、古賀涼子、森美晴、岡本良成、藤田美歌子、折戸公彦、野口慶、三好淳子、森岡基浩、大塚雅巳
    • Organizer
      日本薬学会第137年会
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Presentation] 創薬を目指したHIV-2 Gag MAドメインとカルジオリピンとの結合解析2018

    • Author(s)
      安楽健作、立石大、古賀涼子、福田亮太、坂本亜里紗、大塚雅巳、藤田美歌子
    • Organizer
      第32回日本エイズ学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Presentation] HIV-2 VprにHHCC型亜鉛結合部位を導入すると発現量が上がる2018

    • Author(s)
      古賀涼子、山本充奈美、島垣和功、立石 大、大塚雅巳、藤田美歌子
    • Organizer
      第66回日本ウイルス学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K08861
  • [Presentation] IV-2 Vpxは亜鉛結合部位とポロプロリンモチーフにより発現量を上げる2018

    • Author(s)
      島垣和功、古賀涼子、藤野悠那、チッフチ ハリル イブラヒム、山本充奈美、大塚雅巳、藤田美歌子
    • Organizer
      第32回日本エイズ学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K08861
  • [Presentation] Design and Synthesis of Unexpected Classes of SIRT2 Inhibitors as Antitumor Agents2018

    • Author(s)
      Mohamed O. Radwan,Taha F. S. Ali,Halil I. Cifitci,古賀涼子,岡本良成, 藤田美歌子,大塚雅巳
    • Organizer
      第44回反応と合成の進歩シンポジウム
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Presentation] Kinase Inhibitory Activity of Glycyrrhetic Acid2018

    • Author(s)
      Halil I Ciftci, Mohamed O Radwan, Masami Otsuka, Mikako Fujita
    • Organizer
      The 4th International Symposium on Pharmaceutical and Biomedical Sciences
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K15143
  • [Presentation] Strategic Design of Drug Core Structure -From Natural Molecules to Non-Natural Molecules-2018

    • Author(s)
      Masami Otsuka
    • Organizer
      Karadeniz Technical University-Ege University-Kumamoto University Collaborative Research on Development of Anti-cancer Gypsogenin Derivatives
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Presentation] HIV-2 VpxのポリプロリンモチーフはGag非存在下での蛋白質プロテアソーム分解を防ぐ2018

    • Author(s)
      島垣和功、古賀涼子、藤野悠那、チッフチ ハリル イブラヒム、山本充奈美、大塚雅巳、藤田美歌子
    • Organizer
      第66回日本ウイルス学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K08861
  • [Presentation] Zinc Proteins as Drug Targets2018

    • Author(s)
      Masami Otsuka
    • Organizer
      The 4th International Symposium on Pharmaceutical and Biomedical Sciences
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15143
  • [Presentation] HIV-2 Vpxのポリプロリンモチーフの役割2017

    • Author(s)
      島垣和功、古賀涼子、Halil Ibrahim Ciftci、大塚雅巳、山口佳宏、藤田美歌子
    • Organizer
      第31回日本エイズ学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K08861
  • [Presentation] Structural Basis of Targeting HIV-Gag Matrix, Towards Finding a Cure for HIV Infection2017

    • Author(s)
      Halil Ibrahim Ciftci, Hiroshi Tateishi, Kotaro Koiwai, Ryoko Koga, Fumiaki Yumoto, Toshiya Senda, Masami Otsuka, Mikako Fujita
    • Organizer
      The Second Japan-Turkey International Symposium on Pharmaceutical and Biomedical Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15143
  • [Presentation] HIV-2 Vpxのポリプロリンモチーフの役割2017

    • Author(s)
      島垣和功、古賀涼子、Halil Ibrahim Ciftci、大塚雅巳、山口佳宏、藤田美歌子
    • Organizer
      第31回日本エイズ学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K15143
  • [Presentation] From Natural Bleomycin to Man-Made Bleomycin2017

    • Author(s)
      Masami Otsuka
    • Organizer
      The Second Japan-Turkey International Symposium on Pharmaceutical and Biomedical Sciences
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Presentation] TRAF6 polyubiquitination interruption by a low molecular weight zinc chelator2017

    • Author(s)
      Mohamed O. Radwan, Ryoko Koga, Tomohiko Ejima, Yosuke Kanemaru, Hiroshi Tateishi, Taha F. S. Ali, Halil Il Ciftci, Yuri Shibata, Yuu Taguchi, Jun-ichiro Inoue, Masami Otsuka, Mikako Fujita
    • Organizer
      第35回メディシナルケミストリーシンポジウム
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Presentation] New Sirt2 Inhibitor Based on S-Triryl-L-cysteins Scaffold.2017

    • Author(s)
      Mohamed Osman Radwan, Taha F. S. Ali, Halil Ibrahim Ciftci, Ryoko Koga, Yoshinari Okamoto, Mikako Fujita, Masami Otsuka
    • Organizer
      The Second Japan-Turkey International Symposium on Pharmaceutical and Biomedical Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08861
  • [Presentation] 抗HIV剤BMMPの作用機序解明2017

    • Author(s)
      加茂真宏,立石大,山本充奈美,岡本良成,森川裕子,三隅将吾,大塚雅巳,藤田美歌子
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      東北大学
    • Year and Date
      2017-03-24
    • Data Source
      KAKENHI-PROJECT-26460148
  • [Presentation] Structural Basis of the Interaction between HIV-1 Gag Matrix and IP6. Toward the Development of IP6 Derivative2017

    • Author(s)
      Halilibrahim Ciftci, Hiroshi Tateishi, Kotaro Koiwai, Ryoko Koga, Masami Otsuka, Mikako Fujita, Fumiaki Yumoto, Toshiya Senda
    • Organizer
      第65回日本ウイルス学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K15143
  • [Presentation] Structural Basis of HIV-1 Gag Matrix Targeting by IP6 Derivative2017

    • Author(s)
      Halil I Ciftci, Hiroshi Tateishi, Kotaro Koiwai, Ryoko Koga, Masami Otsuka, Mikako Fujita, Fumiaki Yumoto, Toshiya Senda
    • Organizer
      The 31st Annual Meeting of Japanese Society for AIDS Research
    • Data Source
      KAKENHI-PROJECT-16F16111
  • [Presentation] HIV-2 Vpx/Vpr蛋白質の発現量は亜鉛結合によって制御されている2017

    • Author(s)
      Ryoko Koga, Minami Yamamoto, Hiroshi Tateishi, Halilibrahim Ciftci, Masami Otsuka, Mikako Fujita
    • Organizer
      第65回日本ウイルス学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K08861
  • [Presentation] New Sirt2 Inhibitor based on S-Triryl-L-cysteins scaffold2017

    • Author(s)
      Mohamed Osman Radwan, Taha F. S. Ali, Halil Ibrahim Ciftci, Ryoko Koga, Yoshinari Okamoto, Mikako Fujita, Masami Otsuka
    • Organizer
      The Second Japan-Turkey International Symposium on Pharmaceutical and Biomedical Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Presentation] Development of Anti-HIV and Anti-Cancer Drug Candidates2017

    • Author(s)
      Halil I Ciftci, Kotaro Koiwai, Hiroshi Tateishi, Mehlika D Altintop, Mohamed O Radwan, Belgin Sever, Taha FS Ali, Ryoko Koga, Zafer A Kaplancikli, Ahmet Ozdemir, Fumiaki Yumoto, Toshiya Senda, Mikako Fujita, Masami Otsuka
    • Organizer
      Turkish Japanese Workshop on Bioorganic Medicinal Chemistry and Natural Products
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16F16111
  • [Presentation] Structural Basis of Targeting HIV-Gag Matrix. Towards Finding a Cure for HIV Infection.2017

    • Author(s)
      Halil Ibrahim Ciftci, Hiroshi Tateishi, Kotaro Koiwai, Ryoko Koga, Fumiaki Yumoto, Toshiya Senda, Masami Otsuka, Mikako Fujita
    • Organizer
      The Second Japan-Turkey International Symposium on Pharmaceutical and Biomedical Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08861
  • [Presentation] TRAF6 polyubiquitination interruption by a low molecular weight zinc chelator2017

    • Author(s)
      Mohamed O. Radwan, Ryoko Koga, Tomohiko Ejima, Yosuke Kanemaru, Hiroshi Tateishi, Taha F. S. Ali, Halil Il Ciftci, Yuri Shibata, Yuu Taguchi, Jun-ichiro Inoue, Masami Otsuka, Mikako Fujita
    • Organizer
      第35回メディシナルケミストリーシンポジウム
    • Data Source
      KAKENHI-PROJECT-16K15143
  • [Presentation] Kinase Inhibitory Activity of Gypsogenin Derivatives2017

    • Author(s)
      Halil I Ciftci, Safiye E Ozdemir, Taha FS Ali, Mohamed O Radwan, Hiroshi Tateishi, Ryoko Koga, Mustafa Can, Masami Otsuka, and Mikako Fujita
    • Organizer
      2nd Japan Turkey International Symposium on Pharmaceutical and Biomedical Sciences (JATUSPAB-2)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16F16111
  • [Presentation] ウイルス蛋白質蓄積によりアポトーシスを誘導する新規抗HIV薬の創製2017

    • Author(s)
      立石大、門出和精、古賀涼子、林祐也、東大志、本山敬一、有馬英俊、安楽健作、藤田美歌子、大塚雅巳
    • Organizer
      第35回メディシナルケミストリーシンポジウム
    • Data Source
      KAKENHI-PROJECT-17K08861
  • [Presentation] Expression Level of HIV-2 Vpx/Vpr Proteins is Regulated by their Zinc Binding2017

    • Author(s)
      Ryoko Koga, Minami Yamamoto, Hiroshi Tateishi, Halilibrahim Ciftci, Masami Otsuka, Mikako Fujita
    • Organizer
      第65回日本ウイルス学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K15143
  • [Presentation] Structural Basis of HIV-1 Gag Matrix Targeting by IP6 Derivative2017

    • Author(s)
      Halil I. Ciftci, Hiroshi Tateishi, Kotaro Koiwai, Ryoko Koga, Masami Otsuka, Fumiaki Yumoto, Toshiya Senda
    • Organizer
      第31回日本エイズ学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K15143
  • [Presentation] Zinc-Binding State of HIV-2 VPX/VPR Regulates2017

    • Author(s)
      Ryoko Koga, Minami Yamamoto, Haruna Fujino, Kazunori Shimagaki, Halil Ibrahim Ciftci, Masahiro Kamo, Hiroshi Tateishi, Masami Otsuka, Mikako Fujita
    • Organizer
      The Second Japan-Turkey International Symposium on Pharmaceutical and Biomedical Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Presentation] Structural Basis of Targeting HIV-Gag Matrix. Towards Finding a Cure for HIV Infection2017

    • Author(s)
      Halil Ibrahim Ciftci, Hiroshi Tateishi, Kotaro Koiwai, Ryoko Koga, Fumiaki Yumoto, Toshiya Senda, Masami Otsuka, Mikako Fujita
    • Organizer
      The Second Japan-Turkey International Symposium on Pharmaceutical and Biomedical Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Presentation] NOVEL COMPOUND, OSSL_325096, INDUCES APOPTOSIS IN MULTIPLE MYELOMA CELLS THROUGH VCP INHIBITION2017

    • Author(s)
      Nao Nishimura, Mohamed O. Osman, Masayuki Amano, Shinya Endo, Shikiko Ueno, Nina Ueno, Hiro Tatetsu, Hitoyuki Hata, Yoshinari Okamoto, Masao Matsuoka, Masami Otsuka, Yutaka Okuno
    • Organizer
      The 22nd Congress of European Hematology Association
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15143
  • [Presentation] Bleomycin Revisited: Man-Made Bleomycin with New Function “Surgical Operation” of a Drug Molecule2017

    • Author(s)
      Masami Otsuka
    • Organizer
      Turkish-Japanese Workshop on Bioorganic Medicinal Chemistry and Natural Products
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Presentation] Structural Basis of HIV-1 Gag Matrix Targeting by IP6 Derivative2017

    • Author(s)
      Halil I. Ciftci, Hiroshi Tateishi, Kotaro Koiwai, Ryoko Koga, Masami Otsuka, Fumiaki Yumoto, Toshiya Senda
    • Organizer
      第31回日本エイズ学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Presentation] Structural basis of inositol phosphates recognition in the HIV-1 gag matrix.2017

    • Author(s)
      Halilibrahim Ciftci, Hiroshi Tateishi, Kotaro Koiwai, Ryoko Koga, Masami Otsuka, Mikako Fujita, Fumiaki Yumoto, Toshiya Senda
    • Organizer
      第40回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17K08861
  • [Presentation] Structural Basis of the Interaction between HIV-1 Gag Matrix and IP6 -Toward the Development of IP6 Derivative-2017

    • Author(s)
      Halil I Ciftci, Hiroshi Tateishi, Kotaro Koiwai, Ryoko Koga, Masami Otsuka, Mikako Fujita, Fumiaki Yumoto, and Toshiya Senda
    • Organizer
      The 67th Annual Meeting of the Japanese Society for Virology
    • Data Source
      KAKENHI-PROJECT-16F16111
  • [Presentation] ウイルス蛋白質蓄積によりアポトーシスを誘導する新規抗HIV薬の創製2017

    • Author(s)
      立石大、門出和精、古賀涼子、林祐也、東大志、本山敬一、有馬英俊、安楽健作、藤田美歌子、 大塚雅巳
    • Organizer
      第35回メディシナルケミストリーシンポジウム
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Presentation] Zinc-Binding State of HIV-2 VPX/VPR Regulates2017

    • Author(s)
      Ryoko Koga, Minami Yamamoto, Haruna Fujino, Kazunori Shimagaki, Halil Ibrahim Ciftci, Masahiro Kamo, Hiroshi Tateishi, Masami Otsuka, Mikako Fujita
    • Organizer
      The Second Japan-Turkey International Symposium on Pharmaceutical and Biomedical Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15143
  • [Presentation] Structural Basis of Targeting HIV-1 Gag Matrix. Toward Finding a cure for HIV Infection2017

    • Author(s)
      Halil I Ciftci, Hiroshi Tateishi, Kotaro Koiwai, Ryoko Koga, Fumiaki Yumoto, Toshiya Senda, Masami Otsuka, and Mikako Fujita
    • Organizer
      2nd Japan Turkey International Symposium on Pharmaceutical and Biomedical Sciences (JATUSPAB-2)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16F16111
  • [Presentation] Structural basis of inositol phosphates recognition in the HIV-1 gag matrix2017

    • Author(s)
      Halilibrahim Ciftci, Hiroshi Tateishi, Kotaro Koiwai, Ryoko Koga, Masami Otsuka, Mikako Fujita, Fumiaki Yumoto, Toshiya Senda
    • Organizer
      第40回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-16K15143
  • [Presentation] Structural Basis of the Interaction between HIV-1 Gag Matrix and IP6. Toward the Development of IP6 Derivative.2017

    • Author(s)
      Halilibrahim Ciftci, Hiroshi Tateishi, Kotaro Koiwai, Ryoko Koga, Masami Otsuka, Mikako Fujita, Fumiaki Yumoto, Toshiya Senda
    • Organizer
      第65回日本ウイルス学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K08861
  • [Presentation] Structural Basis of the Interaction between HIV-1 Gag Matrix and IP6. Toward the Development of IP6 Derivative2017

    • Author(s)
      Halilibrahim Ciftci, Hiroshi Tateishi, Kotaro Koiwai, Ryoko Koga, Masami Otsuka, Mikako Fujita, Fumiaki Yumoto, Toshiya Senda
    • Organizer
      第65回日本ウイルス学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Presentation] TRAF6 polyubiquitination interruption by a low molecular weight zinc chelator2017

    • Author(s)
      Mohamed O. Radwan, Ryoko Koga, Tomohiko Ejima, Yosuke Kanemaru, Hiroshi Tateishi, Taha F. S. Ali, Halil Il Ciftci, Yuri Shibata, Yuu Taguchi, Jun-ichiro Inoue, Masami Otsuka, Mikako Fujita
    • Organizer
      第35回メディシナルケミストリーシンポジウム
    • Data Source
      KAKENHI-PROJECT-17K08861
  • [Presentation] Bleomycin Revisited: Man-Made Bleomycin with New Function “Surgical Operation” of a Drug Molecule2017

    • Author(s)
      Masami Otsuka
    • Organizer
      Turkish-Japanese Workshop on Bioorganic Medicinal Chemistry and Natural Products
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15143
  • [Presentation] Zinc-Binding State of HIV-2 VPX/VPR Regulates Their Protein Stability.2017

    • Author(s)
      Ryoko Koga, Minami Yamamoto, Haruna Fujino, Kazunori Shimagaki, Halil Ibrahim Ciftci, Masahiro Kamo, Hiroshi Tateishi, Masami Otsuka, Mikako Fujita
    • Organizer
      The Second Japan-Turkey International Symposium on Pharmaceutical and Biomedical Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08861
  • [Presentation] Structural basis of inositol phosphates recognition in the HIV-1 gag matrix2017

    • Author(s)
      Halilibrahim Ciftci, Hiroshi Tateishi, Kotaro Koiwai, Ryoko Koga, Masami Otsuka, Mikako Fujita, Fumiaki Yumoto, Toshiya Senda
    • Organizer
      第40回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Presentation] NOVEL COMPOUND, OSSL_325096, INDUCES APOPTOSIS IN MULTIPLE MYELOMA CELLS THROUGH VCP INHIBITION2017

    • Author(s)
      Nao Nishimura, Mohamed O. Osman, Masayuki Amano, Shinya Endo, Shikiko Ueno, Nina Ueno, Hiro Tatetsu, Hitoyuki Hata, Yoshinari Okamoto, Masao Matsuoka, Masami Otsuka, Yutaka Okuno
    • Organizer
      The 22nd Congress of European Hematology Association
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Presentation] HIV-2 Vpxのポリプロリンモチーフの役割2017

    • Author(s)
      島垣和功、古賀涼子、Halil Ibrahim Ciftci、大塚雅巳、山口佳宏、藤田美歌子
    • Organizer
      第31回日本エイズ学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Presentation] Structural Basis of HIV-1 Gag Matrix Targeting by IP6 Derivative.2017

    • Author(s)
      Halil I. Ciftci, Hiroshi Tateishi, Kotaro Koiwai, Ryoko Koga, Masami Otsuka, Fumiaki Yumoto, Toshiya Senda
    • Organizer
      第31回日本エイズ学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K08861
  • [Presentation] ウイルス蛋白質蓄積によりアポトーシスを誘導する新規抗HIV薬の創製2017

    • Author(s)
      立石大、門出和精、古賀涼子、林祐也、東大志、本山敬一、有馬英俊、安楽健作、藤田美歌子、 大塚雅巳
    • Organizer
      第35回メディシナルケミストリーシンポジウム
    • Data Source
      KAKENHI-PROJECT-16K15143
  • [Presentation] New Sirt2 Inhibitor based on S-Triryl-L-cysteins scaffold2017

    • Author(s)
      Mohamed Osman Radwan, Taha F. S. Ali, Halil Ibrahim Ciftci, Ryoko Koga, Yoshinari Okamoto, Mikako Fujita, Masami Otsuka
    • Organizer
      The Second Japan-Turkey International Symposium on Pharmaceutical and Biomedical Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15143
  • [Presentation] tructural Basis of Inositol Phosphate Recognition in the HIV-1 Gag Matrix2017

    • Author(s)
      Halil I Ciftci, Hiroshi Tateishi, Kotaro Koiwai, Ryoko Koga, Masami Otsuka, Mikako Fujita, Fumiaki Yumoto, Toshiya Senda
    • Organizer
      Consortium of Biological Sciences
    • Data Source
      KAKENHI-PROJECT-16F16111
  • [Presentation] From Natural Bleomycin to Man-Made Bleomycin2017

    • Author(s)
      Masami Otsuka
    • Organizer
      The Second Japan-Turkey International Symposium on Pharmaceutical and Biomedical Sciences
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15143
  • [Presentation] Expression Level of HIV-2 Vpx/Vpr Proteins is Regulated by their Zinc Binding2017

    • Author(s)
      Ryoko Koga, Minami Yamamoto, Hiroshi Tateishi, Halilibrahim Ciftci, Masami Otsuka, Mikako Fujita
    • Organizer
      第65回日本ウイルス学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H03999
  • [Presentation] 抗HIV活性を持つヘテロ環化合物BMMPの作用機序解明2016

    • Author(s)
      加茂真宏、立石大、山本充奈美、岡本良成、森川裕子、三隅将吾、大塚雅巳、藤田美歌子
    • Organizer
      第30回日本エイズ学会学術集会
    • Place of Presentation
      かごしま県民交流センター
    • Year and Date
      2016-11-24
    • Data Source
      KAKENHI-PROJECT-16K15143
  • [Presentation] Design and synthesis of small molecule Hsp70 inducers2016

    • Author(s)
      Taha Ali, Naomi Taira, Ryoko Koga, Yoshinari Okamoto, Masami Otsuka, Mikako Fujita
    • Organizer
      252nd American Chemical Society Annual Meeting
    • Place of Presentation
      Pennsylvania Convention Center, Philadelphia
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15143
  • [Presentation] A PI(4,5)P2 analog suppresses HIV-1 release and locked-in viralprotein.2016

    • Author(s)
      Hiroshi Tateishi, Kazuaki Monde, Ryoko Koga, Yuya Hayashi, Taishi Higashi, Keiichi Motoyama, Hidetoshi Arima, Kensaku Anraku, Masami Otsuka, Mikako Fujita
    • Organizer
      Cold Spring Harbor Meeting, Retroviruses, 2016
    • Place of Presentation
      Cold Spring Harbor Laboratory, NY, USA
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15143
  • [Presentation] DHMEQを基盤とした新しい生物活性物質の設計と合成、および機能解析2016

    • Author(s)
      本邑健太、岡本良成、古賀涼子、馬塲菜々美、藤田美歌子、梅澤一夫、大塚雅巳
    • Organizer
      第33回日本薬学会九州支部大会
    • Place of Presentation
      鹿児島大学郡元キャンパス
    • Year and Date
      2016-12-03
    • Data Source
      KAKENHI-PROJECT-16K15143
  • [Presentation] Restructuring of the bleomycin Metal Core2016

    • Author(s)
      Taha F. S. Ali, Satomi Ida, Yosuke Kanemaru, Ryoko Koga, Ayumi Tanaka, Akiyuki Hamasaki, Tomohiko Ejima, Mohamed Osman Radwan, Halil Ibrahim Ciftci, Hiromasa Kurosaki, Yoshinari Okamoto, Mikako Fujita, Masami Otsuka
    • Organizer
      Japan-Turkey International Symposium on Pharmaceutical and Biomedical Sciences
    • Place of Presentation
      熊本大学薬学部宮本記念館
    • Year and Date
      2016-10-02
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16F16111
  • [Presentation] Role of zinc binding site of HIV-2 Vpx2016

    • Author(s)
      Minami Yamamoto, Ryoko Koga, Haruna Fujino, Kazunori Shimagaki, Halil Ibrahim Ciftci, Masahiro Kamo, Hiroshi Tateishi, Masami Otsuka, Mikako Fujita
    • Organizer
      2 nd Kumamoto IRCMS International Symposium and 17 th Kumamoto AIDS Seminar
    • Place of Presentation
      熊本県民交流館パレア
    • Year and Date
      2016-10-31
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16F16111
  • [Presentation] Zinc-mediated binding of a low-molecular-weight stabilizer of the host anti-viral factor APOBEC3G2016

    • Author(s)
      Radwan, Mohamed O.; Sonoda, Sachiko; Ejima, Tomohiko; Tanaka, Ayumi; Koga, Ryoko; Okamoto, Yoshinari; Fujita, Mikako; Otsuka, Masami
    • Organizer
      252nd American Chemical Society National Meeting & Exposition
    • Place of Presentation
      Pennsylvania Convention Center
    • Year and Date
      2016-08-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460148
  • [Presentation] Development of Inhibitors for Zinc Proteins Related to Cancer2016

    • Author(s)
      Yoshinari Okamoto, Yasunori Oba, Ayumi Tanaka, Mika Kawabuchi, Hiroshi Tateishi, Mikako Fujita, Masami Otsuka
    • Organizer
      Japan-Turkey International Symposium on Pharmaceutical and Biomedical Sciences
    • Place of Presentation
      Kumamoto University
    • Year and Date
      2016-10-02
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460148
  • [Presentation] N -Substituted-L-Histidine Analogues as Anticancer Agents: A Structure-Activity Relationship Study2016

    • Author(s)
      Taha F. S. Ali, Kana Iwamaru, Halil Ibrahim Ciftci, Ryoko Koga, Hiromasa Kurosaki, Mikako Fujita, Yoshinari Okamoto, Masami Otsuka
    • Organizer
      Japan-Turkey International Symposium on Pharmaceutical and Biomedical Sciences
    • Place of Presentation
      熊本大学薬学部宮本記念館
    • Year and Date
      2016-10-02
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16F16111
  • [Presentation] Synthesis and applications of biotinylated zinc binding SN12016

    • Author(s)
      RADWAN Mohamed、KOGA Ryoko、OKAMOTO Yoshinari、FUJITA Mikako、OTSUKA Masami
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-03-26
    • Data Source
      KAKENHI-PROJECT-26670058
  • [Presentation] 金属キレーターによるHSP70蛋白質の発現上昇2016

    • Author(s)
      平尚未、タハ ファロウク シェハタ アリ、古賀涼子、大塚雅巳、藤田美歌子
    • Organizer
      第33回日本薬学会九州支部大会
    • Place of Presentation
      鹿児島大学郡元キャンパス
    • Year and Date
      2016-12-03
    • Data Source
      KAKENHI-PROJECT-16K15143
  • [Presentation] 抗HIV剤BMMPの作用機序解明と活性改良2016

    • Author(s)
      加茂真宏、立石大、山本充奈美、岡本良成、森川裕子、大塚雅巳、藤田美歌子
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-03-26
    • Data Source
      KAKENHI-PROJECT-26670058
  • [Presentation] Lock-in and apoptosis strategy using a PI(4,5)P2 analog aiming at eradication of HIV2016

    • Author(s)
      Hiroshi Tateishi, Kazuaki Monde, Kensaku Anraku, Ryoko Koga, Yuya Hayashi, Keiichi Motoyama, Hidetoshi Arima, Masami Otsuka, Mikako Fujita
    • Organizer
      2 nd Kumamoto IRCMS International Symposium and 17 th Kumamoto AIDS Seminar
    • Place of Presentation
      熊本県民交流館パレア
    • Year and Date
      2016-10-31
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15143
  • [Presentation] Characters of largely overexpressed HIV accessory proteins Vpx and Vif2016

    • Author(s)
      Kazunori Shimagaki, Halil Ibrahim Ciftci, Ryoko Koga, Haruna Fujino, Minami Yamamoto, Yoshihiro Yamaguchi, Masami Otsuka, Mikako Fujita
    • Organizer
      第64回日本ウイルス学会学術集会
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2016-10-23
    • Data Source
      KAKENHI-PROJECT-16K15143
  • [Presentation] Design and synthesis of small molecule Hsp70 inducers2016

    • Author(s)
      Ali, Taha; Taira, Naomi; Koga, Ryoko; Okamoto, Yoshinari; Otsuka, Masami; Fujita, Mikako
    • Organizer
      252nd American Chemical Society National Meeting & Exposition
    • Place of Presentation
      Pennsylvania Convention Center
    • Year and Date
      2016-08-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460148
  • [Presentation] Synthesis and applications of biotinylated zinc binding SN12016

    • Author(s)
      Mohamed RADWAN, Ryoko KOGA, Yoshinari OKAMOTO, Mikako FUJITA, Masami OTSUKA
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-03-26
    • Data Source
      KAKENHI-PROJECT-26460148
  • [Presentation] Elucidation of action mechanism of heterocyclic compound BMMP having anti-HIV activity2016

    • Author(s)
      Masahiro Kamo, Hiroshi Tateishi, Minami Yamamoto, Yoshinari Okamoto, Yuko Morikawa, Shogo Misumi, Masami Otsuka, Mikako Fujita
    • Organizer
      第64回日本ウイルス学会学術集会
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2016-10-23
    • Data Source
      KAKENHI-PROJECT-16K15143
  • [Presentation] Characters of largely overexpressed HIV accessory proteins Vpx and Vif2016

    • Author(s)
      Kazunori Shimagaki, Halil Ibrahim Ciftci, Ryoko Koga, Haruna Fujino, Minami Yamamoto, Yoshihiro Yamaguchi, Masami Otsuka, Mikako Fujita
    • Organizer
      第64回日本ウイルス学会学術集会
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2016-10-23
    • Data Source
      KAKENHI-PROJECT-16F16111
  • [Presentation] DHMEQを基盤とした新しい生物活性物質の設計と合成,及び機能解析2016

    • Author(s)
      本邑健太,岡本良成,古賀涼子,馬塲菜々美,藤田美歌子,梅澤一夫,大塚雅巳
    • Organizer
      第33回日本薬学会九州支部大会
    • Place of Presentation
      鹿児島大学
    • Year and Date
      2016-12-03
    • Data Source
      KAKENHI-PROJECT-26460148
  • [Presentation] Zinc-mediated binding of a low-molecular-weight stabilizer of the host anti-viral factor APOBEC3G2016

    • Author(s)
      Mohamed Radwan, Sachiko Sonoda, Tomohiko Ejima, Ayumi Tanaka, Ryoko Koga, Yoshinari Okamoto, Mikako Fujita, Masami Otsuka
    • Organizer
      252nd American Chemical Society Annual Meeting
    • Place of Presentation
      Pennsylvania Convention Center, Philadelphia
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15143
  • [Presentation] 抗 HIV 剤 BMMP の作用機序解明と活性改良2016

    • Author(s)
      加茂 真宏, 立石 大, 山本 充奈美, 岡本 良成, 森川 裕子, 大塚 雅巳, 藤田美歌子
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-03-26
    • Data Source
      KAKENHI-PROJECT-26460148
  • [Presentation] Gag蛋白質を標的とした細胞死誘導型新規抗HIV薬の開発研究2016

    • Author(s)
      立石大、門出和精、村尾直樹、古賀涼子、林祐也、東大志、本山敬一、有馬英俊、安楽健作、藤田美歌子、大塚雅巳
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-03-26
    • Data Source
      KAKENHI-PROJECT-26670058
  • [Presentation] Role of zinc binding site of HIV-2 Vpx2016

    • Author(s)
      Minami Yamamoto, Ryoko Koga, Haruna Fujino, Kazunori Shimagaki, Halil Ibrahim Ciftci, Masahiro Kamo, Hiroshi Tateishi, Masami Otsuka, Mikako Fujita
    • Organizer
      2 nd Kumamoto IRCMS International Symposium and 17 th Kumamoto AIDS Seminar
    • Place of Presentation
      熊本県民交流館パレア
    • Year and Date
      2016-10-31
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15143
  • [Presentation] Significance of Zinc Binding Site of HIV-2 Vpx2016

    • Author(s)
      Minami Yamamoto, Ryoko Koga, Haruna Fujino, Kazunori Shimagaki, Halil Ibrahim Ciftci, Masahiro Kamo, Hiroshi Tateishi, Masami Otsuka, Mikako Fujita
    • Organizer
      Japan-Turkey International Symposium on Pharmaceutical and Biomedical Sciences
    • Place of Presentation
      熊本大学薬学部宮本記念館
    • Year and Date
      2016-10-02
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16F16111
  • [Presentation] Restructuring of the bleomycin Metal Core2016

    • Author(s)
      Taha F. S. Ali, Satomi Ida, Yosuke Kanemaru, Ryoko Koga, Ayumi Tanaka, Akiyuki Hamasaki, Tomohiko Ejima, Mohamed Osman Radwan, Halil Ibrahim Ciftci, Hiromasa Kurosaki, Yoshinari Okamoto, Mikako Fujita, Masami Otsuka
    • Organizer
      Japan-Turkey International Symposium on Pharmaceutical and Biomedical Sciences
    • Place of Presentation
      熊本大学薬学部宮本記念館
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15143
  • [Presentation] Pr55Gag蛋白質を標的とした新規抗HIV剤の開発研究2015

    • Author(s)
      立石大、門出和精、村尾直樹、古賀涼子、林祐也、東大志、本山敬一、有馬英俊、安楽健作、藤田美歌子、大塚雅巳
    • Organizer
      第33回メディシナルケミストリーシンポジウム
    • Place of Presentation
      幕張国際研修センター
    • Year and Date
      2015-11-25
    • Data Source
      KAKENHI-PROJECT-26670058
  • [Presentation] Elucidation of action mechanism of BMMP and improvement of its activity by chemical modification2015

    • Author(s)
      Masahiro Kamo, Hiroshi Tateishi, Minami Yamamoto, Yoshinari Okamoto, Yuko Morikawa, Shogo Misumi, Masami Otsuka, Mikako Fujita
    • Organizer
      第63回日本ウイルス学会学術集会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2015-11-22
    • Data Source
      KAKENHI-PROJECT-26670058
  • [Presentation] SAMHD1分解におけるHIV-2 Vpx C末端ポリプロリンモチーフの役割2015

    • Author(s)
      藤田美歌子、Halil Ibrahim Ciftci、藤野悠那、古賀涼子、山本充奈美、大塚雅巳
    • Organizer
      第29回日本エイズ学会学術集会
    • Place of Presentation
      東京ドームホテル
    • Year and Date
      2015-11-30
    • Data Source
      KAKENHI-PROJECT-26670058
  • [Presentation] New strategy to suppress HIV release by a PI(4,5)P2 mimic2015

    • Author(s)
      Mikako Fujita, Hiroshi Tateishi, Kazuaki Monde, Naoki Murao, Yuya Hayashi, Taishi Higashi, Keiichi Motoyama, Hidetoshi Arima, Kensaku Anraku, Masami Otsuka
    • Organizer
      第63回日本ウイルス学会学術集会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2015-11-22
    • Data Source
      KAKENHI-PROJECT-26670058
  • [Presentation] 抗 HIV 剤 BMMP の作用機序解明及び活性改良2015

    • Author(s)
      Masahiro Kamo, Hiroshi Tateishi, Minami Yamamoto, Yoshinari Okamoto, Yuko Morikawa, Shogo Misumi, Masami Otsuka, Mikako Fujita
    • Organizer
      第63回日本ウイルス学会学術集会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2015-11-22
    • Data Source
      KAKENHI-PROJECT-26460148
  • [Presentation] Roles of poly-proline motif of HIV-2 Vpx protein2015

    • Author(s)
      Ciftci Halil Ibrahim, Demirci Hasan, Haruna Fujino, Ryoko Koga, Minami Yamamoto, Masami Otsuka, Mikako Fujita
    • Organizer
      第63回日本ウイルス学会学術集会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2015-11-22
    • Data Source
      KAKENHI-PROJECT-26670058
  • [Presentation] TRAF6ポリユビキチン化を抑制する低分子化合物によるシグナル伝達制御の検討2015

    • Author(s)
      古賀涼子、江島智彦、金丸陽亮、柴田佑里、田口祐、井上純一郎、大塚雅巳、藤田美歌子
    • Organizer
      第33回メディシナルケミストリーシンポジウム
    • Place of Presentation
      幕張国際研修センター
    • Year and Date
      2015-11-25
    • Data Source
      KAKENHI-PROJECT-26670058
  • [Presentation] Development of a low molecular compound targetingTRAF6 protein2015

    • Author(s)
      Ryoko Koga, Tomohiko Ejima, Yosuke Kanemaru, Yuri Shibata, Yuu Taniguchi, Jun-ichiro Inoue, Masami Otsuka, Mikako Fujita
    • Organizer
      International Symposium on Chronic Inflammatory Diseases, Kumamoto
    • Place of Presentation
      熊本大学大江キャンパス
    • Year and Date
      2015-10-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670058
  • [Presentation] Roles of zinc-binding motif of HIV-2 Vpx protein2015

    • Author(s)
      Minami Yamamoto, Haruna Fujino, Kazunori Shimagaki, Ryoko Koga, Ciftci Halil Ibrahim, Masami Otsuka, Mikako Fujita
    • Organizer
      第63回日本ウイルス学会学術集会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2015-11-22
    • Data Source
      KAKENHI-PROJECT-26670058
  • [Presentation] HIV-1 Gagのイノシトールリン脂質結合部位を標的とした膜移行阻害剤の合成2014

    • Author(s)
      立石大,安楽健作,古賀涼子,岡本良成,藤田美歌子,大塚雅巳
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本大学
    • Data Source
      KAKENHI-PROJECT-23590131
  • [Presentation] ウイルスコアの脱殻促進を目指した新規抗HIV薬の創製2014

    • Author(s)
      加茂真宏,岡本良成,大塚雅巳,藤田美歌子
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本大学
    • Data Source
      KAKENHI-PROJECT-23590131
  • [Presentation] ファルネシルトランスフェラーゼの特異的阻害を目的とした亜鉛キレーターの設計及び合成2014

    • Author(s)
      田中亜友美,岡本良成,藤田美歌子,梅澤一夫,玉野井冬彦,大塚雅巳
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本大学
    • Data Source
      KAKENHI-PROJECT-23590131
  • [Presentation] ウイルスコアの脱殻過程における作用を目指した新規抗HIV薬の創製2013

    • Author(s)
      加茂真宏、岡本良成、大塚雅巳、藤田美歌子
    • Organizer
      第30回日本薬学会九州支部大会
    • Place of Presentation
      長崎国際大学
    • Year and Date
      2013-12-07
    • Data Source
      KAKENHI-PROJECT-24659048
  • [Presentation] ウイルスコアの脱殻課程における作用を目指した新規抗HIV薬の創製2013

    • Author(s)
      加茂真宏,岡本良成,大塚雅巳,藤田美歌子
    • Organizer
      第30回日本薬学会九州支部大会
    • Place of Presentation
      長崎国際大学
    • Data Source
      KAKENHI-PROJECT-23590131
  • [Presentation] ペプチド性新規DNA切断分子の設計と合成2013

    • Author(s)
      井田智弓, 岡本良成, 藤田美歌子, 黒崎博雅, 大塚雅巳
    • Organizer
      第30回日本薬学会九州支部大会
    • Place of Presentation
      長崎国際大学, 長崎
    • Year and Date
      2013-12-08
    • Data Source
      KAKENHI-PROJECT-23390028
  • [Presentation] NF-κB 活性化シグナル伝達分子に対する亜鉛フィンガー蛋白質阻害剤の作用2013

    • Author(s)
      古賀涼子, 江島智彦, 金丸陽亮, 田口祐, 柴田佑里, 井上純一郎, 大塚雅巳, 藤田美歌子
    • Organizer
      第31回メディシナルケミストリーシンポジウム
    • Place of Presentation
      広島アステールプラザ, 広島
    • Year and Date
      2013-11-21
    • Data Source
      KAKENHI-PROJECT-23390028
  • [Presentation] HIV-1 MA蛋白質と強く結合するイノシトールリン脂質誘導体の合成と評価2013

    • Author(s)
      安楽健作、立石大、古賀涼子、東大志、本山敬一、有馬英俊、大塚雅巳、藤田美歌子
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-29
    • Data Source
      KAKENHI-PROJECT-24659048
  • [Presentation] Inositol phosphates in calcium signaling and HIV replication DPhG2013

    • Author(s)
      Masami Otsuka
    • Organizer
      (Deutsche Pharmazeutische Gesellschaft) Annual Meeting 2013
    • Place of Presentation
      University of Freiburg , ドイツ
    • Year and Date
      2013-10-11
    • Data Source
      KAKENHI-PROJECT-23390028
  • [Presentation] HIV-1 放出抑制剤を目指したイノシトールリン脂質誘導体の合成と評価2013

    • Author(s)
      立石大, 安楽健作, 古賀涼子, 岡本良成, 藤田美歌子, 大塚雅巳
    • Organizer
      第31回メディシナルケミストリーシンポジウム
    • Place of Presentation
      広島アステールプラザ, 広島
    • Year and Date
      2013-11-20
    • Data Source
      KAKENHI-PROJECT-23390028
  • [Presentation] ウイルスコアの脱殻過程における作用を目指した新規抗HIV薬の創製2013

    • Author(s)
      加茂真宏、岡本良成、大塚雅巳、藤田美歌子
    • Organizer
      第31回メディシナルケミストリーシンポジウム
    • Place of Presentation
      広島アステールプラザ
    • Year and Date
      2013-11-21
    • Data Source
      KAKENHI-PROJECT-24659048
  • [Presentation] HIV-1放出抑制剤を目指したイノシトールリン脂質誘導体の合成と評価2013

    • Author(s)
      立石大,安楽健作,古賀涼子,岡本良成,藤田美歌子,大塚雅巳
    • Organizer
      第31回メディシナルケミストリーシンポジウム
    • Place of Presentation
      アステールプラザ(広島)
    • Data Source
      KAKENHI-PROJECT-23590131
  • [Presentation] ペプチド性新規DNA切断分子の設計と合成2013

    • Author(s)
      井田智弓,岡本良成,藤田美歌子,黒崎博雅,大塚雅巳
    • Organizer
      第30回日本薬学会九州支部大会
    • Place of Presentation
      長崎国際大学
    • Data Source
      KAKENHI-PROJECT-23590131
  • [Presentation] ペプチド性新規DNA切断分子の設計と合成2013

    • Author(s)
      井田智弓、岡本良成、藤田美歌子、黒崎博雅、大塚雅巳
    • Organizer
      第30回日本薬学会九州支部大会
    • Place of Presentation
      長崎国際大学
    • Year and Date
      2013-12-08
    • Data Source
      KAKENHI-PROJECT-24659048
  • [Presentation] ウイルスコアの脱殻過程における作用を目指した新規抗HIV薬の創製2013

    • Author(s)
      加茂真宏, 岡本良成, 大塚雅巳, 藤田美歌子
    • Organizer
      第31回メディシナルケミストリーシンポジウム
    • Place of Presentation
      広島アステールプラザ, 広島
    • Year and Date
      2013-11-21
    • Data Source
      KAKENHI-PROJECT-23390028
  • [Presentation] HIV-1 MA 蛋白質と強く結合するイノシトールリン脂質誘導体の合成と評価2013

    • Author(s)
      安楽健作, 立石大, 古賀涼子, 東大志, 本山敬一, 有馬英俊, 大塚雅巳, 藤田美歌子
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      パシフィコ横浜, 横浜
    • Year and Date
      2013-03-29
    • Data Source
      KAKENHI-PROJECT-23390028
  • [Presentation] Inositol phosphates in calcium signaling and HIV replication DPhG (Deutsche Pharmazeutische Gesellschaft)2013

    • Author(s)
      Masami Otsuka
    • Organizer
      Annual Meeting 2013
    • Place of Presentation
      University of Freiburg
    • Year and Date
      2013-10-11
    • Data Source
      KAKENHI-PROJECT-24659048
  • [Presentation] NF-κB活性化シグナル伝達分子に対する亜鉛フィンガー蛋白質阻害剤の作用2013

    • Author(s)
      古賀涼子、江島智彦、金丸陽亮、田口祐、柴田佑里、井上純一郎、大塚雅巳、藤田美歌子
    • Organizer
      第30回日本薬学会九州支部大会
    • Place of Presentation
      長崎国際大学
    • Year and Date
      2013-12-07
    • Data Source
      KAKENHI-PROJECT-24659048
  • [Presentation] NF-κB活性化シグナル伝達分子に対する亜鉛フィンガー蛋白質阻害剤の作用2013

    • Author(s)
      古賀涼子、江島智彦、金丸陽亮、田口祐、柴田佑里、井上純一郎、大塚雅巳、藤田美歌子
    • Organizer
      第31回メディシナルケミストリーシンポジウム
    • Place of Presentation
      広島アステールプラザ
    • Year and Date
      2013-11-21
    • Data Source
      KAKENHI-PROJECT-24659048
  • [Presentation] HIV-1放出抑制剤を目指したイノシトールリン脂質誘導体の合成と評価2013

    • Author(s)
      立石大,安楽健作,古賀涼子,岡本良成,藤田美歌子,大塚雅巳
    • Organizer
      第31回メディシナルケミストリーシンポジウム
    • Place of Presentation
      アステールプラザ(広島)
    • Data Source
      KAKENHI-PROJECT-23590131
  • [Presentation] ファルネシルトランスフェラーゼの特異的阻害を目的とした亜鉛キレーターの設計及び合成2013

    • Author(s)
      田中亜友美,岸田明日美,小畑恵美子,岡本良成,梅澤一夫,大塚雅巳
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-23590131
  • [Presentation] ファルネシルトランスフェラーゼの特異的阻害剤を目的とした亜鉛キレーターの設計及び合成2013

    • Author(s)
      田中亜友美, 岸田明日美, 小畑恵美子, 岡本良成, 梅澤一夫, 大塚雅巳
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      パシフィコ横浜, 横浜
    • Year and Date
      2013-03-28
    • Data Source
      KAKENHI-PROJECT-23390028
  • [Presentation] ウイルスコアの脱殻過程における作用を目指した新規抗HIV薬の創製2013

    • Author(s)
      加茂真宏, 岡本良成, 大塚雅巳, 藤田美歌子
    • Organizer
      第30回日本薬学会九州支部大会
    • Place of Presentation
      長崎国際大学, 長崎
    • Year and Date
      2013-12-07
    • Data Source
      KAKENHI-PROJECT-23390028
  • [Presentation] HIV-1 放出抑制剤を目指したイノシトールリン脂質誘導体2013

    • Author(s)
      立石大, 安楽健作, 古賀涼子, 藤田美歌子, 大塚雅巳
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      パシフィコ横浜, 横浜
    • Year and Date
      2013-03-28
    • Data Source
      KAKENHI-PROJECT-23390028
  • [Presentation] ウイルスコアの脱殻課程における作用を目指した新規抗HIV薬の創製2013

    • Author(s)
      加茂真宏,岡本良成,大塚雅巳,藤田美歌子
    • Organizer
      第31回メディシナルケミストリーシンポジウム
    • Place of Presentation
      アステールプラザ(広島)
    • Data Source
      KAKENHI-PROJECT-23590131
  • [Presentation] ファルネシルトランスフェラーゼの特異的阻害を目的とした亜鉛キレーターの設計及び合成2013

    • Author(s)
      田中亜友美,岸田明日美,小畑恵美子,岡本良成,梅澤一夫,大塚雅巳
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      神奈川県横浜市・パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-23590131
  • [Presentation] NF-κB 活性化シグナル伝達分子に対する亜鉛フィンガー蛋白質阻害剤の作用2013

    • Author(s)
      古賀涼子, 江島智彦, 金丸陽亮, 田口祐, 柴田佑里, 井上純一郎, 大塚雅巳, 藤田美歌子
    • Organizer
      第30回日本薬学会九州支部大会
    • Place of Presentation
      長崎国際大学, 長崎
    • Year and Date
      2013-12-07
    • Data Source
      KAKENHI-PROJECT-23390028
  • [Presentation] ファルネシルトランスフェラーゼの特異的阻害剤を目的とした亜鉛キレーターの設計及び合成2013

    • Author(s)
      田中亜友美、岸田明日美、小畑恵美子、岡本良成、梅澤一夫、大塚雅巳
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-28
    • Data Source
      KAKENHI-PROJECT-24659048
  • [Presentation] HIV-1放出抑制剤を目指したイノシトールリン脂質誘導体の合成と評価2013

    • Author(s)
      立石大、安楽健作、古賀涼子、岡本良成、藤田美歌子、大塚雅巳
    • Organizer
      第31回メディシナルケミストリーシンポジウム
    • Place of Presentation
      広島アステールプラザ
    • Year and Date
      2013-11-20
    • Data Source
      KAKENHI-PROJECT-24659048
  • [Presentation] ウイルスコアの脱殻課程における作用を目指した新規抗HIV薬の創製2013

    • Author(s)
      加茂真宏,岡本良成,大塚雅巳,藤田美歌子
    • Organizer
      第31回メディシナルケミストリーシンポジウム
    • Place of Presentation
      アステールプラザ(広島)
    • Data Source
      KAKENHI-PROJECT-23590131
  • [Presentation] HIV-1放出抑制剤を目指したイノシトールリン脂質誘導体2013

    • Author(s)
      立石大、安楽健作、古賀涼子、藤田美歌子、大塚雅巳
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-28
    • Data Source
      KAKENHI-PROJECT-24659048
  • [Presentation] 亜鉛フィンガー蛋白質阻害剤SN-1の作用機序解明を目指した研究2012

    • Author(s)
      園田祥子、安楽健作、古賀涼子、田口祐、井上純一郎、岡本良成、藤田美歌子、大塚雅巳
    • Organizer
      第29回日本薬学会九州支部大会
    • Place of Presentation
      熊本大学薬学部
    • Data Source
      KAKENHI-PROJECT-24659048
  • [Presentation] イノシトールリン酸を基盤とした生物機能性分子の設計と合成2012

    • Author(s)
      安楽健作、舛田岳史、立石大、岡本良成、藤田美歌子、大塚雅巳
    • Organizer
      第38回反応と合成の進歩シンポジウム
    • Place of Presentation
      タワーホール船堀
    • Data Source
      KAKENHI-PROJECT-24659048
  • [Presentation] イノシトールリン酸を基盤とした生物機能性分子の設計と合成2012

    • Author(s)
      安楽健作,舛田岳史,筑葉晃一,立石大,岡本良成,藤田美歌子,大塚雅巳
    • Organizer
      第38回反応と合成の進歩シンポジウム
    • Place of Presentation
      タワーホール船堀(東京都江戸川区)
    • Data Source
      KAKENHI-PROJECT-23590131
  • [Presentation] ファルネシルトランスフェラーゼの特異的阻害を目的とした亜鉛キレーターの設計及び合成2012

    • Author(s)
      田中亜友美,岸田明日美,小畑恵美子,岡本良成,梅澤一夫,大塚雅巳
    • Organizer
      第29回日本薬学会九州支部大会
    • Place of Presentation
      熊本大学
    • Data Source
      KAKENHI-PROJECT-23590131
  • [Presentation] ファルネシルトランスフェラーゼの特異的阻害を目的とした亜鉛キレーターの設計および合成2012

    • Author(s)
      田中亜友美,岸田明日美,小畑恵美子,岡本良成,梅澤一夫,大塚雅巳
    • Organizer
      第29回日本薬学会九州支部大会
    • Place of Presentation
      熊本県熊本市・熊本大学薬学部
    • Data Source
      KAKENHI-PROJECT-23590131
  • [Presentation] 亜鉛フィンガータンパク質阻害剤SN-1の作用機序解明を目指した研究2012

    • Author(s)
      園田祥子,安楽健作,古賀涼子,田口祐,井上純一郎,岡本良成,藤田美歌子,大塚雅巳
    • Organizer
      第29回日本薬学会九州支部大会
    • Place of Presentation
      熊本大学
    • Data Source
      KAKENHI-PROJECT-23590131
  • [Presentation] イノシトールリン酸を基盤とした生物機能性分子の設計と合成2012

    • Author(s)
      安楽健作,舛田岳史,筑葉晃一,立石大,岡本良成,藤田美歌子,大塚雅巳
    • Organizer
      第38回反応と合成の進歩シンポジウム
    • Place of Presentation
      東京都江戸川区・タワーホール船堀
    • Data Source
      KAKENHI-PROJECT-23590131
  • [Presentation] イノシトールリン酸を基盤とした生物機能性分子の設計と合成2012

    • Author(s)
      安楽健作, 舛田岳史, 立石大, 岡本良成, 藤田美歌子, 大塚雅巳
    • Organizer
      第38回反応と合成の進歩シンポジウム
    • Place of Presentation
      タワーホール船堀, 東京
    • Data Source
      KAKENHI-PROJECT-23390028
  • [Presentation] HIV-1放出抑制剤を目指したイノシトールリン脂質誘導体2012

    • Author(s)
      立石大、安楽健作、大塚雅巳、藤田美歌子
    • Organizer
      第26回日本エイズ学会学術集会
    • Place of Presentation
      慶應義塾大学日吉キャンパス
    • Year and Date
      2012-11-24
    • Data Source
      KAKENHI-PROJECT-24659048
  • [Presentation] 亜鉛フィンガー蛋白質阻害剤SN-1 の作用機序解明を目指した研究2012

    • Author(s)
      園田祥子, 安楽健作, 古賀涼子, 田口祐, 井上純一郎, 岡本良成, 藤田美歌子, 大塚雅巳
    • Organizer
      第29回日本薬学会九州支部大会
    • Place of Presentation
      熊本大学薬学部, 熊本
    • Data Source
      KAKENHI-PROJECT-23390028
  • [Presentation] 人工亜鉛キレーターを持つADAM ファミリーメタロプロテアーゼ阻害剤の合成2012

    • Author(s)
      川田代康介, 岡本良成, 佐谷秀行, 大塚雅巳
    • Organizer
      第29回日本薬学会九州支部大会
    • Place of Presentation
      熊本大学薬学部, 熊本
    • Data Source
      KAKENHI-PROJECT-23390028
  • [Presentation] 人工亜鉛キレーターを持つADAMファミリーメタロプロテアーゼ阻害剤の合成2012

    • Author(s)
      川田代康介,岡本良成,佐谷秀行,大塚雅巳
    • Organizer
      第29回日本薬学会九州支部大会
    • Place of Presentation
      熊本県熊本市・熊本大学薬学部
    • Data Source
      KAKENHI-PROJECT-23590131
  • [Presentation] NF-kB阻害剤としてのazaDHMEQの合成2012

    • Author(s)
      馬場菜々美,野田陽平,藤田雅紀,岡本良成,梅澤一夫,大塚雅巳
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      北海道大学
    • Data Source
      KAKENHI-PROJECT-23590131
  • [Presentation] HIV-1 放出抑制剤を目指したイノシトールリン脂質誘導体2012

    • Author(s)
      立石大, 安楽健作, 大塚雅巳, 藤田美歌子
    • Organizer
      第26回日本エイズ学会学術集会
    • Place of Presentation
      慶應義塾大学日吉キャンパス, 横浜
    • Year and Date
      2012-11-24
    • Data Source
      KAKENHI-PROJECT-23390028
  • [Presentation] 人工亜鉛キレーターを持つADAMファミリーメタロプロテアーゼ阻害剤の合成2012

    • Author(s)
      川田代康介、岡本良成、佐谷秀行、大塚雅巳
    • Organizer
      第29回日本薬学会九州支部大会
    • Place of Presentation
      熊本大学薬学部
    • Data Source
      KAKENHI-PROJECT-24659048
  • [Presentation] 人工亜鉛キレーターを持つADAMファミリーメタロプロテアーゼ阻害剤の合成2012

    • Author(s)
      川田代康介,岡本良成,佐谷秀行,大塚雅巳
    • Organizer
      第29回日本薬学会九州支部大会
    • Place of Presentation
      熊本大学
    • Data Source
      KAKENHI-PROJECT-23590131
  • [Presentation] 亜鉛フィンガータンパク質阻害剤SN-1の作用機序解明を目指した研究2012

    • Author(s)
      園田祥子,安楽健作,古賀涼子,田口祐,井上純一郎,岡本良成,藤田美歌子,大塚雅巳
    • Organizer
      第29回日本薬学会九州支部大会
    • Place of Presentation
      熊本県熊本市・熊本大学薬学部
    • Data Source
      KAKENHI-PROJECT-23590131
  • [Presentation] PH ドメインタンパク質に結合し膜に移動させるmyo-イノシトール誘導体の合成2012

    • Author(s)
      筑葉晃一, 工藤康太, 舛田岳史, 安楽健作, 大塚雅巳
    • Organizer
      第29回日本薬学会九州支部大会
    • Place of Presentation
      熊本大学薬学部, 熊本
    • Data Source
      KAKENHI-PROJECT-23390028
  • [Presentation] PHドメインタンパク質に結合し膜に移動させるmyo-イノシトール誘導体の合成2012

    • Author(s)
      筑葉晃一、工藤康太、舛田岳史、安楽健作、大塚雅巳
    • Organizer
      第29回日本薬学会九州支部大会
    • Place of Presentation
      熊本大学薬学部
    • Data Source
      KAKENHI-PROJECT-24659048
  • [Presentation] ファルネシルトランスフェラーゼの特異的阻害を目的とした亜鉛キレーターの設計および合成2012

    • Author(s)
      田中亜友美、岸田明日美、小畑恵美子、岡本良成、梅澤一夫、大塚雅巳
    • Organizer
      第29回日本薬学会九州支部大会
    • Place of Presentation
      熊本大学薬学部
    • Data Source
      KAKENHI-PROJECT-24659048
  • [Presentation] ファルネシルトランスフェラーゼの特異的阻害を目的とした亜鉛キレーターの設計および合成2012

    • Author(s)
      田中亜友美, 岸田明日美, 小畑恵美子, 岡本良成, 梅澤一夫, 大塚雅巳
    • Organizer
      第29回日本薬学会九州支部大会
    • Place of Presentation
      熊本大学薬学部, 熊本
    • Data Source
      KAKENHI-PROJECT-23390028
  • [Presentation] Design and Synthesis of Anti-HIV-1 Agent that Targets Pr55Gag Protein2011

    • Author(s)
      Kensaku Anraku, Mikako Fujita, Masami Otsuka
    • Organizer
      8^<th> AFMC International Medicinal Chemistry Symposium
    • Place of Presentation
      京王プラザホテル(東京)
    • Year and Date
      2011-11-30
    • Data Source
      KAKENHI-PROJECT-22659024
  • [Presentation] 新規チオール化合物の合成と機能解析2011

    • Author(s)
      肥田知浩、金丸陽亮、岡本良成、藤田美歌子、大塚雅巳
    • Organizer
      第28回日本薬学会九州支部大会
    • Place of Presentation
      福岡大学薬学部(福岡)
    • Year and Date
      2011-12-10
    • Data Source
      KAKENHI-PROJECT-22659024
  • [Presentation] PHドメイン分子によるHIV-1放出の制御2011

    • Author(s)
      藤田美歌子、安楽健作、大塚雅巳
    • Organizer
      第25回日本エイズ学会学術集会
    • Place of Presentation
      ハイアットリージェンシー東京(東京)
    • Year and Date
      2011-11-30
    • Data Source
      KAKENHI-PROJECT-22659024
  • [Presentation] Systematic Synthesis of all Regioisomer of Inositol Phosphates2011

    • Author(s)
      T. Masuda, K. Anraku, K. Sato, Y. Okamoto, M. Otsuka
    • Organizer
      AIMECS 2011
    • Place of Presentation
      京王プラザホテル
    • Data Source
      KAKENHI-PROJECT-23590131
  • [Presentation] 新規チオール化合物の合成と機能解析2011

    • Author(s)
      肥田知浩,金丸陽亮,岡本良成,藤田美歌子,大塚雅巳
    • Organizer
      第28回日本薬学会九州支部大会
    • Place of Presentation
      福岡大学
    • Data Source
      KAKENHI-PROJECT-23590131
  • [Presentation] Systematic Synthesis of all Regioisomers of Inositol Phosphates2011

    • Author(s)
      Takeshi Masuda, Kensaku Anraku, Kaori Sato, Yoshinari Okamoto, Masami Otsuka
    • Organizer
      8th AFMC International Medicinal Chemistry Symposium
    • Place of Presentation
      京王プラザホテル, 東京
    • Year and Date
      2011-12-01
    • Data Source
      KAKENHI-PROJECT-23390028
  • [Presentation] NF-kB阻害剤としてのazaDHMEQの合成2011

    • Author(s)
      馬場菜々美,野田陽平,藤田雅紀,岡本良成,梅澤一夫,大塚雅巳
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      北海道大学
    • Data Source
      KAKENHI-PROJECT-23590131
  • [Presentation] 副作用を起こさない非ステロイド性抗炎症薬の創製2011

    • Author(s)
      山川直樹, 末益慎太郎, 勝孝, 岡本良成, 大塚雅巳, 水島徹
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      ツインメッセ静岡
    • Year and Date
      2011-03-31
    • Data Source
      KAKENHI-PROJECT-20590104
  • [Presentation] Systematic Synthesis of all Regioisomer of Inositol Phosphates2011

    • Author(s)
      舛田岳史,安楽健作,佐藤かおり,岡本良成,大塚雅巳
    • Organizer
      AIMECS 2011
    • Place of Presentation
      京王プラザホテル(東京都)
    • Data Source
      KAKENHI-PROJECT-23590131
  • [Presentation] Systematic Synthesis of all Regioisomers of Inositol Phosphates2011

    • Author(s)
      Takeshi Masuda, Kensaku Anraku, Kaori Sato, Yoshinari Okamoto, Masami Otsuka
    • Place of Presentation
      京王プラザホテル(東京)
    • Year and Date
      2011-12-01
    • Data Source
      KAKENHI-PROJECT-22659024
  • [Presentation] 新規チオール化合物の合成と機能解析2011

    • Author(s)
      肥田知浩,金丸陽亮,岡本良成,藤田美歌子,大塚雅巳
    • Organizer
      第28回 日本薬学会九州支部大会
    • Place of Presentation
      福岡大学
    • Data Source
      KAKENHI-PROJECT-23590131
  • [Presentation] 酸性脂質類によるHIV-1増殖の抑制2011

    • Author(s)
      安楽健作、藤田美歌子、大塚雅巳
    • Organizer
      第25回日本エイズ学会学術集会
    • Place of Presentation
      ハイアットリージェンシー東京(東京)
    • Year and Date
      2011-11-30
    • Data Source
      KAKENHI-PROJECT-22659024
  • [Presentation] Design and Synthesis of Anti-HIV-1 Agent that Targets Pr55Gag Protein2011

    • Author(s)
      Kensaku Anraku, Mikako Fujita, Masami Otsuka
    • Organizer
      8th AFMC International Medicinal Chemistry Symposium
    • Place of Presentation
      京王プラザホテル, 東京
    • Year and Date
      2011-11-30
    • Data Source
      KAKENHI-PROJECT-23390028
  • [Presentation] Systematic synthesis of all regioisomers of inositol phosphates.2010

    • Author(s)
      Takashi Masuda, Kensaku Anraku, Kaori Sato, Yoshinari Okamoto, Masami Otsuka
    • Organizer
      PACIFICHEM 2010
    • Place of Presentation
      Convention Center, Honolulu
    • Year and Date
      2010-12-19
    • Data Source
      KAKENHI-PROJECT-20390033
  • [Presentation] 脳虚血後の脳保護に関与するPI3K-Akt経路を標的としたミオイノシトール誘導体の合成2010

    • Author(s)
      工藤康太、安楽健作、岡本良成、藤田美歌子、河野隆幸、森岡基浩、倉津純一、大塚雅巳
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      桃太郎アリーナ、岡山
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-20390033
  • [Presentation] イノシトールリン酸類における全位置異性体の系統的合成法の開拓2010

    • Author(s)
      舛田岳史、安楽健作、佐藤かおり、岡本良成、大塚雅巳
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      桃太郎アリーナ、岡山
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-20390033
  • [Presentation] イノシトールリン酸類における全位置異性体の系統的合成法の開拓2010

    • Author(s)
      舛田岳史, 安楽健作, 佐藤かおり, 岡本良成, 大塚雅巳
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      桃太郎アリーナ(岡山)
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-20590104
  • [Presentation] Systematic synthesis of all regioisomers of inositol phosphate2010

    • Author(s)
      Takashi Masuda, Kensaku Anraku, Kaori Sato, Yoshinari Okamoto, Masami Otsuka
    • Organizer
      Pacifichem2010
    • Place of Presentation
      Kamehameha Halls (Honolulu)U.S.A.
    • Year and Date
      2010-12-19
    • Data Source
      KAKENHI-PROJECT-20590104
  • [Presentation] HIV-1 MA蛋白質と強く結合する低分子化合物の探索2010

    • Author(s)
      安楽健作、福田亮太、大塚雅巳、藤田美歌子
    • Organizer
      第58回日本ウイルス学会学術集会
    • Place of Presentation
      徳島あわぎんホール(徳島)
    • Year and Date
      2010-11-08
    • Data Source
      KAKENHI-PROJECT-22659024
  • [Presentation] 新規DNA切断分子の合成研究2010

    • Author(s)
      坂本慎弥, 松本正裕, 岡本良成, 大塚雅巳
    • Organizer
      第27回日本薬学会九州支部大会
    • Place of Presentation
      長崎大学
    • Year and Date
      2010-12-12
    • Data Source
      KAKENHI-PROJECT-20590104
  • [Presentation] 新規DNA切断分子の合成研究2010

    • Author(s)
      坂本慎弥、松本正裕、岡本良成、大塚雅巳
    • Organizer
      第27回日本薬学会九州支部大会
    • Place of Presentation
      長崎大学薬学部、長崎
    • Year and Date
      2010-12-12
    • Data Source
      KAKENHI-PROJECT-20390033
  • [Presentation] Pr55Gagを標的とした抗HIV-1薬開発のための基礎的研究2010

    • Author(s)
      安楽健作、福田亮太、藤田美歌子、大塚雅巳
    • Organizer
      第29回メディシナルケミストリーシンポジウム
    • Place of Presentation
      京都テルサ、京都
    • Year and Date
      2010-11-18
    • Data Source
      KAKENHI-PROJECT-20390033
  • [Presentation] 脳虚血後の脳保護に関与するPI3K-Akt経路を標的としたミオイノシトール誘導体の合成2010

    • Author(s)
      工藤康太, 安楽健作, 岡本良成, 藤田美歌子, 河野隆幸, 森岡基浩, 倉津純一, 大塚雅巳
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      桃太郎アリーナ(岡山)
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-20590104
  • [Presentation] Systematic synthesis of all regioisomers of inositol phosphates2010

    • Author(s)
      Takashi Masuda, Kensaku Anraku, Kaori Sato, Yoshinari Okamoto, Masami Otsuka
    • Place of Presentation
      PACIFICHEM 2010、Convention Center,(Honolulu)
    • Year and Date
      2010-12-19
    • Data Source
      KAKENHI-PROJECT-22659024
  • [Presentation] Pr55^<Gag>を標的とした抗HIV-1薬開発のための基礎的研究2010

    • Author(s)
      安楽健作、福田亮太、藤田美歌子、大塚雅巳
    • Organizer
      第29回メディシナルケミストリーシンポジウム
    • Place of Presentation
      京都テルサ(京都)
    • Year and Date
      2010-11-18
    • Data Source
      KAKENHI-PROJECT-22659024
  • [Presentation] ADAMファミリーメタロプロテアーゼ特異的阻害剤の合成研究2009

    • Author(s)
      大場誉徳、井上奈月、穴井里美、岡本良成、佐谷秀行、大塚雅巳
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      国立京都国際会館、京都
    • Year and Date
      2009-03-26
    • Data Source
      KAKENHI-PROJECT-20390033
  • [Presentation] Highly sensitive analysis for interactionbetween human immunodeficiency virus type 1 Gag and phosphoinositide derivatives based on surface plasmon resonance2009

    • Author(s)
      安楽健作、藤田美歌子、大塚雅巳
    • Organizer
      第10回熊本エイズセミナー
    • Place of Presentation
      ホテル日航熊本、熊本
    • Year and Date
      2009-09-28
    • Data Source
      KAKENHI-PROJECT-20390033
  • [Presentation] HIV-1 Vif阻害剤を指向した亜鉛キレーターの合成と活性評価2009

    • Author(s)
      江島智彦, 岡本良成, 大塚雅巳, 藤田美歌子
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都国際会館
    • Year and Date
      2009-03-26
    • Data Source
      KAKENHI-PROJECT-20590104
  • [Presentation] HIV-1複製に関与するイノシトールリン脂質類とGag関連蛋白質との結合の定量的解析2009

    • Author(s)
      藤田美歌子、安楽健作、大塚雅巳
    • Organizer
      第57回日本ウイルス学会学術集会
    • Place of Presentation
      都市センターホテル、東京
    • Year and Date
      2009-10-25
    • Data Source
      KAKENHI-PROJECT-20390033
  • [Presentation] RANKを三量体化させる人工低分子化合物の開発とそれによるシグナル伝達制御システム構築の試み2009

    • Author(s)
      廣田真由子, 入江佳奈子, 小田一貴, 岡本良成, 合田仁, 井上純一郎, 藤田美歌子, 大塚雅巳
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-12-11
    • Data Source
      KAKENHI-PROJECT-20590104
  • [Presentation] イノシトールリン酸類における全位置異性体の系統的合成法の開拓2009

    • Author(s)
      舛田岳史, 安楽健作, 佐藤かおり, 岡本良成, 大塚雅巳
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都国際会館
    • Year and Date
      2009-03-26
    • Data Source
      KAKENHI-PROJECT-20590104
  • [Presentation] ADAMファミリーメタロプロテアーゼ選択的阻害剤の合成研究2009

    • Author(s)
      大場誉徳, 井上奈月, 穴井美里, 岡本良成, 佐谷秀行, 大塚雅巳
    • Organizer
      第26回日本薬学会九州支部大会
    • Place of Presentation
      九州大学
    • Year and Date
      2009-12-13
    • Data Source
      KAKENHI-PROJECT-20590104
  • [Presentation] イノシトールリン酸類における全位置異性体の系統的合成法の開拓2009

    • Author(s)
      舛田岳史、安楽健作、佐藤かおり、岡本良成、大塚雅巳
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      国立京都国際会館、京都
    • Year and Date
      2009-03-26
    • Data Source
      KAKENHI-PROJECT-20390033
  • [Presentation] RANKを三量体化させる人工低分子化合物の開発とそれによるシグナル伝達制御システム構築の試み2009

    • Author(s)
      廣田真友子、入江佳奈子、尾田一貴、岡本良成、合田仁、井上純一郎、藤田美歌子、大塚雅巳
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜、横浜
    • Year and Date
      2009-12-11
    • Data Source
      KAKENHI-PROJECT-20390033
  • [Presentation] ADAMファミリーメタロプロテアーゼ特異的阻害剤の合成研究2009

    • Author(s)
      大場誉徳, 井上奈月, 穴井美里, 岡本良成, 佐谷秀行, 大塚雅巳
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都国際会館
    • Year and Date
      2009-03-28
    • Data Source
      KAKENHI-PROJECT-20590104
  • [Presentation] HIV-1蛋白質とイノシトールリン酸との結合解析2008

    • Author(s)
      藤田美歌子、安楽健作、福田亮太、大塚雅巳
    • Organizer
      第22回日本エイズ学会学術集会
    • Place of Presentation
      大阪国際交流センター、大阪
    • Year and Date
      2008-11-26
    • Data Source
      KAKENHI-PROJECT-20390033
  • [Presentation] ADAMファミリーメタロプロテアーゼ特異的阻害剤の合成研究2008

    • Author(s)
      大場誉徳, 井上奈月, 穴井美里, 岡本良成, 大塚雅巳
    • Organizer
      第25回有機合成化学セミナー
    • Place of Presentation
      阿蘇プラザホテル(熊本)
    • Year and Date
      2008-09-08
    • Data Source
      KAKENHI-PROJECT-20590104
  • [Presentation] DHMEQ類似体の合成研究2008

    • Author(s)
      野田陽平, 岡本良成, 梅澤一夫, 大塚雅巳
    • Organizer
      第25回日本薬学会九州支部大会
    • Place of Presentation
      九州保健福祉大学(宮崎)
    • Year and Date
      2008-12-07
    • Data Source
      KAKENHI-PROJECT-20590104
  • [Presentation] がんに関わる生体反応を標的としたDNA切断分子の合成研究2008

    • Author(s)
      岡本良成, 松本正裕, 藤田美歌子, 大塚雅巳
    • Organizer
      第12回がん分子標的治療研究会総会
    • Place of Presentation
      学術総合センター(東京)
    • Year and Date
      2008-06-26
    • Data Source
      KAKENHI-PROJECT-20590104
  • [Presentation] がんに関わる生体反応を標的としたDNA切断分子の合成研究2008

    • Author(s)
      岡本良成、松本正裕、藤田美歌子、大塚雅巳
    • Organizer
      第12回がん分子標的治療研究会総会
    • Place of Presentation
      学術総合センター、東京
    • Year and Date
      2008-06-26
    • Data Source
      KAKENHI-PROJECT-20390033
  • [Presentation] HIVアクセサリータンパク質Nef翻訳に重要なNef2 mRNAの5’非翻訳領域

    • Author(s)
      高宗暢暁、山本充奈美、原田圭輔、藤田美歌子、大塚雅巳、杉本幸彦、庄司省三、三隅将吾
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸国際会議場(兵庫県)
    • Data Source
      KAKENHI-PROJECT-24659048
  • [Presentation] SAMHD1-independent function of HIV-2 Vpx protein

    • Author(s)
      チッフチ ハリル イブラヒム、古賀涼子、岩谷靖雅、野間口雅子、足立昭夫、大塚雅巳、藤田美歌子
    • Organizer
      第27回日本エイズ学会学術集会
    • Place of Presentation
      熊本国際交流会館(熊本県)
    • Data Source
      KAKENHI-PROJECT-24659048
  • [Presentation] Nef2 mRNAの5’非翻訳領域に含まれるNef翻訳に重要なcis領域

    • Author(s)
      高宗暢暁、山本充奈美、原田圭輔、藤田美歌子、大塚雅巳、杉本幸彦、庄司省三、三隅将吾
    • Organizer
      第27回日本エイズ学会学術集会
    • Place of Presentation
      熊本国際交流会館(熊本県)
    • Data Source
      KAKENHI-PROJECT-24659048
  • [Presentation] 新規HIV-1放出抑制剤を目指したイノシトールリン脂質誘導体の創製

    • Author(s)
      立石大,安楽健作,村尾直樹,門出和精,原田信志,古賀涼子,岡本良成,藤田美歌子,大塚雅巳
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸学院大学・兵庫医療大学
    • Year and Date
      2015-03-26 – 2015-03-28
    • Data Source
      KAKENHI-PROJECT-26460148
  • [Presentation] Gagに作用する抗HIV剤BMMPの作用機序解明と活性改良の試み

    • Author(s)
      加茂真宏,立石大,岡本良成,森川裕子,大塚雅巳,藤田美歌子
    • Organizer
      第28回日本エイズ学会学術集会・総会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2014-12-03 – 2014-12-05
    • Data Source
      KAKENHI-PROJECT-26460148
  • [Presentation] Crystal Structure of IMP-1 Metallo-&#61538;-lactamase in Complex with Citric Acid and Inhibition by Citric Acid Derivative

    • Author(s)
      黒崎博雅、山口佳宏、安部美希、山縣ゆり子、荒川宜親、柴山恵吾、藤田美歌子、岡本良成、大塚雅巳
    • Organizer
      88回日本細菌学会総会
    • Place of Presentation
      長良川国際会議場
    • Year and Date
      2015-03-26 – 2015-03-28
    • Data Source
      KAKENHI-PROJECT-26670058
  • [Presentation] NF-κB 活性化シグナル伝達分子に対する亜鉛フィンガー蛋白質阻害剤の作用

    • Author(s)
      古賀涼子、江島智彦、金丸陽亮、田口祐、柴田佑里、井上純一郎、大塚雅巳、藤田美歌子
    • Organizer
      第30回日本薬学会九州支部大会
    • Place of Presentation
      長崎国際大学(長崎県)
    • Data Source
      KAKENHI-PROJECT-23390028
  • [Presentation] ウイルスコアの脱殻過程における作用を目指した新規抗HIV薬の創製

    • Author(s)
      加茂真宏、岡本良成、大塚雅巳、藤田美歌子
    • Organizer
      第31回メディシナルケミストリーシンポジウム
    • Place of Presentation
      広島アステールプラザ(広島県)
    • Data Source
      KAKENHI-PROJECT-23390028
  • [Presentation] HIV-2 Vpx蛋白質の多量化の解析

    • Author(s)
      藤野悠那、古賀涼子、大塚雅巳、藤田美歌子
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸国際会議場(兵庫県)
    • Data Source
      KAKENHI-PROJECT-24659048
  • [Presentation] NF-κB 活性化シグナル伝達分子に対する亜鉛フィンガー蛋白質阻害剤の作用

    • Author(s)
      古賀涼子、江島智彦、金丸陽亮、田口祐、柴田佑里、井上純一郎、大塚雅巳、藤田美歌子
    • Organizer
      第31回メディシナルケミストリーシンポジウム
    • Place of Presentation
      広島アステールプラザ(広島県)
    • Data Source
      KAKENHI-PROJECT-24659048
  • [Presentation] HIV-1 放出抑制剤を目指したイノシトールリン脂質誘導体の合成と評価

    • Author(s)
      立石大、安楽健作、古賀涼子、岡本良成、藤田美歌子、大塚雅巳
    • Organizer
      第31回メディシナルケミストリーシンポジウム
    • Place of Presentation
      広島アステールプラザ(広島県)
    • Data Source
      KAKENHI-PROJECT-24659048
  • [Presentation] HIV-2 Vpxにおける亜鉛フィンガー、ポリプロリンモチーフの役割と翻訳後修飾の意義

    • Author(s)
      山本充奈美、藤野悠那、古賀涼子、チッフチ ハリル、三隅将吾、大塚雅巳、藤田美歌子
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-26670058
  • [Presentation] nositol phosphates in calcium signaling and HIV replication

    • Author(s)
      大塚雅巳
    • Organizer
      DPhG Annual Meeting 2013
    • Place of Presentation
      フライブルク大学(ドイツ)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659048
  • [Presentation] マクロファージにおけるSAMHD1非依存的なHIV-2 Vpxの機能

    • Author(s)
      山本充奈美、野間口雅子、古賀涼子、岩谷靖雅、高宗暢暁、三隅将吾、大塚雅巳、 足立昭夫、藤田美歌子
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸国際会議場(兵庫県)
    • Data Source
      KAKENHI-PROJECT-24659048
  • [Presentation] マクロファージにおけるSAMHD1非依存的なHIV-2 Vpxの機能

    • Author(s)
      山本充奈美、野間口雅子、古賀涼子、岩谷靖雅、高宗暢暁、三隅将吾、大塚雅巳、足立昭夫、藤田美歌子
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸国際会議場(兵庫県)
    • Data Source
      KAKENHI-PROJECT-23390028
  • [Presentation] 新規HIV-1 放出抑制剤を目指したイノシトールリン脂質誘導体の創製

    • Author(s)
      立石大、安楽健作、村尾直樹、門出和精、原田信志、古賀涼子、岡本良成、藤田美歌子、大塚雅巳
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      兵庫医療大学
    • Year and Date
      2015-03-25 – 2015-03-28
    • Data Source
      KAKENHI-PROJECT-26670058
  • [Presentation] HIV-1MAタンパク質とホスファチジルイノシトール4,5-2リン酸との結合部位を標的とした抗HIV薬の設計と合成

    • Author(s)
      安楽健作,立石大,古賀涼子,岡本良成,藤田美歌子,大塚雅巳
    • Organizer
      第32回メディシナルケミストリーシンポジウム
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2014-11-26 – 2014-11-28
    • Data Source
      KAKENHI-PROJECT-26460148
  • [Presentation] Mutational Analysis of HIV-2 Vpx concerning on ability to degrade SAMHD1

    • Author(s)
      Ciftci Halil Ibrahim、藤野悠那、古賀涼子、山本充奈美、川村宗吾、岩谷靖雅、大塚雅巳、藤田美歌子
    • Organizer
      第28回日本エイズ学会学術集会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2014-12-03 – 2014-12-05
    • Data Source
      KAKENHI-PROJECT-26670058
  • [Presentation] A novel zinc chelating inhibotor of NF-kB activation : Biotin modification and docking study

    • Author(s)
      モハメド オスマン ラドワン,古賀涼子,岡本良成,藤田美歌子,大塚雅巳
    • Organizer
      第31回日本薬学会九州支部大会
    • Place of Presentation
      第一薬科大学
    • Year and Date
      2014-12-06 – 2014-12-07
    • Data Source
      KAKENHI-PROJECT-26460148
  • [Presentation] ペプチド性新規DNA切断分子の設計と合成

    • Author(s)
      井田智弓、岡本良成、藤田美歌子、黒崎博雅、大塚雅巳
    • Organizer
      第30回日本薬学会九州支部大会
    • Place of Presentation
      長崎国際大学(長崎県)
    • Data Source
      KAKENHI-PROJECT-24659048
  • [Presentation] HIV-2 Vpx蛋白質の多量化の解析

    • Author(s)
      藤野悠那、古賀涼子、大塚雅巳、藤田美歌子
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸国際会議場(兵庫県)
    • Data Source
      KAKENHI-PROJECT-23390028
  • [Presentation] Gag に作用する抗 HIV 化合物 BMMP の作用機序解明と活性改良の検討

    • Author(s)
      加茂真宏、立石大、岡本良成、森川裕子、大塚雅巳、藤田美歌子
    • Organizer
      第62回日本ウイルス学会学術集会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-11-10 – 2014-11-12
    • Data Source
      KAKENHI-PROJECT-26670058
  • [Presentation] HIV-1放出阻害を目指したイノシトールリン脂質誘導体の創製

    • Author(s)
      立石大、安楽健作、村尾直樹、古賀涼子、岡本良成、大塚雅巳、藤田美歌子
    • Organizer
      第28回日本エイズ学会学術集会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2014-12-03 – 2014-12-05
    • Data Source
      KAKENHI-PROJECT-26670058
  • [Presentation] HIVアクセサリータンパク質Nef翻訳に重要なNef2 mRNAの5’非翻訳領域

    • Author(s)
      高宗暢暁、山本充奈美、原田圭輔、藤田美歌子、大塚雅巳、杉本幸彦、庄司省三、三隅将吾
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸国際会議場(兵庫県)
    • Data Source
      KAKENHI-PROJECT-23390028
  • [Presentation] Gagに作用する抗HIV化合物BMMPの作用機序解明と活性改良の検討

    • Author(s)
      加茂真宏,立石大,岡本良成,森川裕子,大塚雅巳,藤田美歌子
    • Organizer
      第62回日本ウイルス学会学術集会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-11-10 – 2014-11-12
    • Data Source
      KAKENHI-PROJECT-26460148
  • [Presentation] Novel metal chelating molecules with anticancer activity

    • Author(s)
      Taha ALI,岩丸佳奈,Halil CIFTCI,古賀涼子,黒崎博雅,藤田美歌子,岡本良成,秀拓一郎,牧野敬史,倉津純一,中尾光善,梅澤一夫,Mohamed ABDEL-AZIZ,Gamal El-Din ABUO-RAHMA,Eman BESHR,大塚雅巳
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸学院大学・兵庫医療大学
    • Year and Date
      2015-03-26 – 2015-03-28
    • Data Source
      KAKENHI-PROJECT-26460148
  • [Presentation] カルバゾールとフェノチアジン誘導体の設計・合成および抗ガン活性の評価

    • Author(s)
      チッフチ ハリル イブラヒム、Aysenur Erdogana、Emire Arkan、古賀涼子、大塚雅巳、藤田美歌子、Mahmur Kus、Mustafa Can
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      デザイン・クリエイティブセンター神戸
    • Year and Date
      2015-03-25 – 2015-03-28
    • Data Source
      KAKENHI-PROJECT-26670058
  • [Presentation] Nef2 mRNAの5’非翻訳領域に含まれるNef翻訳に重要なcis領域

    • Author(s)
      高宗暢暁、山本充奈美、原田圭輔、藤田美歌子、大塚雅巳、杉本幸彦、庄司省三、三隅将吾
    • Organizer
      第27回日本エイズ学会学術集会
    • Place of Presentation
      熊本国際交流会館(熊本県)
    • Data Source
      KAKENHI-PROJECT-23390028
  • [Presentation] ウイルスコアの脱殻過程における作用を目指した新規抗HIV薬の創製

    • Author(s)
      加茂真宏、岡本良成、大塚雅巳、藤田美歌子
    • Organizer
      第31回メディシナルケミストリーシンポジウム
    • Place of Presentation
      広島アステールプラザ(広島県)
    • Data Source
      KAKENHI-PROJECT-24659048
  • [Presentation] 抗HIV剤BMMPの作用機序解明と構造改変の試み

    • Author(s)
      加茂真宏,立石大,山本充奈美,岡本良成,森川裕子,三隅将吾,大塚雅巳,藤田美歌子
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸学院大学・兵庫医療大学
    • Year and Date
      2015-03-26 – 2015-03-28
    • Data Source
      KAKENHI-PROJECT-26460148
  • [Presentation] NF-κB 活性化シグナル伝達分子に対する亜鉛フィンガー蛋白質阻害剤の作用

    • Author(s)
      古賀涼子、江島智彦、金丸陽亮、田口祐、柴田佑里、井上純一郎、大塚雅巳、藤田美歌子
    • Organizer
      第30回日本薬学会九州支部大会
    • Place of Presentation
      長崎国際大学(長崎県)
    • Data Source
      KAKENHI-PROJECT-24659048
  • [Presentation] Gagに作用する抗HIV剤BMMPの作用機序解明と活性改良の試み

    • Author(s)
      加茂真宏、立石大、岡本良成、森川裕子、大塚雅巳、藤田美歌子
    • Organizer
      第28回日本エイズ学会学術集会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2014-12-03 – 2014-12-05
    • Data Source
      KAKENHI-PROJECT-26670058
  • [Presentation] ペプチド性新規DNA切断分子の設計と合成

    • Author(s)
      井田智弓、岡本良成、藤田美歌子、黒崎博雅、大塚雅巳
    • Organizer
      第30回日本薬学会九州支部大会
    • Place of Presentation
      長崎国際大学(長崎県)
    • Data Source
      KAKENHI-PROJECT-23390028
  • [Presentation] SAMHD1-independent function of HIV-2 Vpx protein

    • Author(s)
      チッフチ ハリル イブラヒム、古賀涼子、岩谷靖雅、野間口雅子、足立昭夫、大塚雅巳、藤田美歌子
    • Organizer
      第27回日本エイズ学会学術集会
    • Place of Presentation
      熊本国際交流会館(熊本県)
    • Data Source
      KAKENHI-PROJECT-23390028
  • [Presentation] ウイルスコアの脱殻過程における作用を目指した新規抗HIV薬の創製

    • Author(s)
      加茂真宏、岡本良成、大塚雅巳、藤田美歌子
    • Organizer
      第30回日本薬学会九州支部大会
    • Place of Presentation
      長崎国際大学(長崎県)
    • Data Source
      KAKENHI-PROJECT-24659048
  • [Presentation] NF-κB 活性化シグナル伝達分子に対する亜鉛フィンガー蛋白質阻害剤の作用

    • Author(s)
      古賀涼子、江島智彦、金丸陽亮、田口祐、柴田佑里、井上純一郎、大塚雅巳、藤田美歌子
    • Organizer
      第31回メディシナルケミストリーシンポジウム
    • Place of Presentation
      広島アステールプラザ(広島県)
    • Data Source
      KAKENHI-PROJECT-23390028
  • [Presentation] HIV-1 放出抑制剤を目指したイノシトールリン脂質誘導体の合成と評価

    • Author(s)
      立石大、安楽健作、古賀涼子、岡本良成、藤田美歌子、大塚雅巳
    • Organizer
      第31回メディシナルケミストリーシンポジウム
    • Place of Presentation
      広島アステールプラザ(広島県)
    • Data Source
      KAKENHI-PROJECT-23390028
  • [Presentation] ウイルスコアの脱殻過程における作用を目指した新規抗HIV薬の創製

    • Author(s)
      加茂真宏、岡本良成、大塚雅巳、藤田美歌子
    • Organizer
      第30回日本薬学会九州支部大会
    • Place of Presentation
      長崎国際大学(長崎県)
    • Data Source
      KAKENHI-PROJECT-23390028
  • [Presentation] TRAF6ポリユビキチン化を抑制する低分子化合物のシグナル伝達経路hwの作用と抑制メカニズムの検討

    • Author(s)
      古賀涼子、江島智彦、金丸陽亮、柴田佑里、田口祐、井上純一郎、大塚雅巳、藤田美歌子
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      兵庫医療大学
    • Year and Date
      2015-03-25 – 2015-03-28
    • Data Source
      KAKENHI-PROJECT-26670058
  • [Presentation] Inositol phosphates in calcium signaling and HIV replication

    • Author(s)
      大塚雅巳
    • Organizer
      DPhG Annual Meeting 2013
    • Place of Presentation
      フライブルク大学(ドイツ)
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390028
  • [Presentation] HIV-1 MA 蛋白質とホスファチジルイノシトール 4,5-2 リン酸との結合部位を標的とした抗 HIV 薬の設計と合成

    • Author(s)
      安楽健作、立石大、古賀涼子、岡本良成、藤田美歌子、大塚雅巳
    • Organizer
      第32回メディシナルケミストリーシンポジウム
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2014-11-26 – 2014-11-28
    • Data Source
      KAKENHI-PROJECT-26670058
  • [Presentation] HIV2 Vpx における亜鉛フィンガーおよび C 末端ポリプロリンモチーフの役割

    • Author(s)
      藤野悠那、山本充奈美、Halil Ibrahim Ciftci、島垣和功、古賀涼子、大塚雅巳、藤田美歌子
    • Organizer
      第62回日本ウイルス学会学術集会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-11-10 – 2014-11-12
    • Data Source
      KAKENHI-PROJECT-26670058
  • [Presentation] TRAF6ポリユビキチン化を制御する低分子化合物のシグナル伝達阻害と制御メカニズムに関する検討

    • Author(s)
      古賀涼子、江島智彦、金丸陽亮、柴田佑里、田口祐、井上純一郎、大塚雅巳、藤田美歌子
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-26670058
  • [Presentation] 抗HIV剤BMMPの作用機序解明と構造改変の試み

    • Author(s)
      加茂真宏、立石大、山本充奈美、岡本良成、森川裕子、三隅将吾、大塚雅巳、藤田美歌子
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      兵庫医療大学
    • Year and Date
      2015-03-25 – 2015-03-28
    • Data Source
      KAKENHI-PROJECT-26670058
  • 1.  OKAMOTO Yoshinari (20194409)
    # of Collaborated Projects: 12 results
    # of Collaborated Products: 128 results
  • 2.  FUJITA Mikako (00322256)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 120 results
  • 3.  OKURA Ichiro (90089821)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  YAMASAKI Tetsuo (60182474)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  SUGIURA Yukio (40025698)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  YANO Shigenobu (60011186)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  NAGANO Tetsuo (20111552)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  UMEZAWA Kazuo (70114402)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  FUJII Yuki (50007564)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  SAKURAI Hiromu (30065916)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  立石 大 (50846011)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 9 results
  • 12.  ANRAKU Kensaku (80389543)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 14 results
  • 13.  INOUE Junichiro (70176428)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  UMEMORI Hisashi (20242117)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  MATSUDA Satoru (50242110)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  YAMAMOTO Tadashi (40134621)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  OKUNO Yasushi (20283666)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  OKAWARA Tadashi (60040325)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  IMOTO Masaya (60213253)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  KATSUKI Hiroshi (40240733)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  SEKI Takahiro (50335650)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  MAKINO KEISHI (90381011)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  中村 聡 (50227899)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  小澤 俊彦 (40160858)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  井上 英史 (20184765)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  樋口 恒彦 (50173159)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  庄司 省三 (60040317)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  山梨 裕司 (40202387)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  中村 英夫 (30359963)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  秀 拓一郎 (40421820)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  篠島 直樹 (50648269)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  黒田 順一郎 (90536731)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  VERMA Inder M.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  CIFTCI HALIL
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 30 results
  • 35.  KURAUCHI Yuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 36.  NAKAMURA Teruya
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 37.  林 宏典
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 38.  尹 浩信
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 39.  大杉 剛生
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 40.  伊藤 昭博
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 41.  吉田 稔
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 42.  森井 孝
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi