KIKKAWA Ushio 吉川潮

Researcher Number	40150354
Other IDs
Affiliation (based on the past Project Information) *help	2015: 神戸大学, バイオシグナル総合研究センター, 教授 2008 – 2010: Kobe University, 自然科学系先端融合研究環バイオシグナル研究センター, 教授 1992 – 2006: Kobe University Biosignal Research Center Professor, バイオシグナル研究センター, 教授 1998: Biosignal Research Center, Kobe University Professor, 教授 1991: Kobe University School of Medicine, Lecturer, 医学部, 講師 1986 – 1989: 神戸大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Pathological medical chemistry / Biological Sciences / General medical chemistry / General medical chemistry Except Principal Investigator General medical chemistry / Pathological medical chemistry / Biological Sciences / Tumor biology / Pathological medical chemistry / Plant nutrition/Soil science / General medical chemistry
Keywords	Principal Investigator 蛋白質リン酸化酵素 / PKB / ストレス / 熱ショック / PKC / ホスファチジルイノシトール3-キナーゼ / プロテインキナーゼC / PHドメイン / 細胞死 / RACプロテインキナーゼ … More / protein kinase / ストレス刺激 / Hsp27 / 活性制御 / シグナル伝達 / TPA / synaptosome / AFX / protein kinase C / PH domain / RAC-protein kinase / 分子ファミリー / Protein Kinase C / ジアシルグリセロール / 細胞内情報伝達 / 転写因子 / Akt / オリゴマー / 蛋白質リン酸化反応 / 免疫沈降法 / 発現細胞 / GTP結合性蛋白質 / 融合蛋白質 / 機能ドメイン / HL-60 cell / cell differentiation / S. cerevisiae / cell growth / release / Protein kinase C / 受容伝達機構 / 生理活性物質 / NIH3T3細胞 / 細胞増殖 / DiC_8 / T cell / LTP(長期増強) / 血小板 / tamoxifen / アルコ-ルリン脂質 / 脂肪酸 / Ca^<2+>応答性 / down regulation / calpain / PDBu結合能 / Apoptosis / Transcription factor / Heat shock / Growth factor / Protein kinase / リン酸化部位特異的抗体 / 細胞増殖因子 / membrane translocation / GFP-fusion protein / mutant / hydrogen peroxide / tyrosine phosphorylation / diacylglycerol / 細胞膜移行 / GFP融合蛋白質 / 変異体 / 酸化ストレス / チロシンリン酸化 / regulation of activation / phosphatidylinositol 3-kinase / stress / functional domain / 蛋白質相互作用 / プロテインキナーゼ / column chromatography / G protein / protein family / molecular cloning / 結合蛋白質 / 分子生物学 / SH2ドメイン / カラムクロマトグラフィー / 分子クローニング / Diacylglycerol / Protein Phosphorylation / Signal Transduction / ジアシルグリセロ-ル / プロテインキナ-ゼC / タンパク質リン酸化反応 / プロティンキナーゼC / STAT3 / Rheb / TIP41 / PP242 / アミノ酸 / mTIP41 / AMPK / ラパマイシン / ホスファターゼ / 栄養 / mTOR / 肝細胞増殖因子 / カスパーゼ / フォークヘッド転写因子 / 過酸化水素処理 / ホスホリパーゼD / ゴルジ体 / 紫外線 / 質量分析法 / PKCδ / ミオシンII / 修飾反応 / 一酸化窒素 / 高浸透圧 / 発現酵素 … More Except Principal Investigator プロテインキナーゼC / 細胞増殖 / mTOR / 細胞内情報伝達 / PROTEIN KINASE C / 生理活性物質 / プロテインキナーゼ / ラパマイシン / ホスホリパーゼD / カルシウム / Ca^<2+> / イノシトールリン脂質 / PRAS40 / rapamycin / PLANT PROTEIN KINASE / SIGNAL TRANSDUCTION / PROTEIN KINASE / Phospholipase D / Signal transduction / プロテインキナ-ゼC / cDNA / 蛋白質リン酸化反応 / 特異抗体 / カルパイン / phorbol ester / 蛋白質リン酸化酵素 / 細胞成長 / アミノ酸 / カルシウムイオン / 細胞分化 / 細胞内情報伝達機構 / ジアシルグリセロール / ホスホリパーゼA_2 / アミノ酸代謝 / 活性酸素 / p53 / DNA損傷 / 細胞老化 / signal transduction / inositol phospholipid / diacylglycerol / cell differentiation / cell proliferation / protein kinase C / ダウンレギュレーション / 蛋白質限定分解反応 / ホルボールエステル / シアシルグリセロ-ル / イノシト-ルリン脂質 / ホルボ-ルエステル / ジアシルグリセロ-ル / BIOLOGICAL ACTIVE SUBSTANCES / MOLECULAR CLONING / SPECIFIC ANTIBODY / モノクロナール抗体 / 受容伝達機構 / クローニング / receptor / protein kinase / phosphatidylinositol / tumorpromotor / neurotransmitter / hormone / 生体膜 / プロティンキナーゼC / 情報受容伝達 / 外界シグナル / 受容体 / 情報伝達 / 発癌プロモーター / 神経伝達物質 / ホルモン / amino acids / side effect / restenosis prevention / cell growth / immunosuppressant / 血小板現象 / 中性脂肪上昇 / 創傷治癒遅延 / Rapamycin / タンパク質リン酸化 / 創傷治癒 / 血小板減少 / 4EBP1 / mTOR複合体 / raptor / リン酸化 / 副作用 / 再狭窄阻害 / 免疫抑制剤 / G_<M2> gangliosidosis / ADP-ribosylation factor / G-protein / G_<M2> activator / 活性化因子 / G蛋白質 / ホスホリバーゼD / コリン燐脂質 / ADP-リボシル化因子 / G_<M2>アクチベーター / PLANT SIGNAL TRANSDUCTION / NITRATE REDUCTASE / PLANT PKC / SIGNAL TRANSbUSTION / DLANT PKC / SIGNAL TRANSDLICTION / PROTEIN KINASEC / Diacylglycerol / Phospholipase A2 / Protein kinase C / ジグリセリド / ホスホリパーゼA2 / Molecular Biology / Calcium Ion / Protein Phosphorylation / Protein Kinase C / Signal Transduction / 触媒機能 / 発現細胞系 / 情報受容機構 / プロテンキナ-ゼC / phosohatidylethanol / 分子種特異的活性調節物質 / 分化 / EGF受容体 / cDNAクローン / 分子多様性 / 遺伝子クローニング / 発がん遺伝子 / 細胞成長因子 / アポトーシス / 蛋白質分解酵素 / シグナル伝達 / 細胞周期 / カスパーゼ / WDドメイン / mLST8 / 核酸生合成 / ピリミジン生合成 / CAD / 核酸新生 / Tuberin / TSC / がん抑制遺伝子 / Hamartin / GAPドメイン / 結節性硬化症 / 一酸化窒素合成酵素 / チオレドキシン / 核局在化シグナル / ホスファチジルイノシトール3キナーゼ / ストレス / 低分子量G蛋白質 / ホスホリパーゼA / NO(一酸化窒素) / Fas / PI 3キナーゼ / 核-細胞質間物質輸送 / PKC(プロテインキナーゼC) / PLC(ホスホリパーゼC) / PLD(ホスホリパーゼD) / PAF-アセチルヒドロラーゼ / 創薬 / 構造解析 / 情報伝達機構網 / チロシンキナーゼ / アミノ酸バランス / CG-NAP / PKN / ターゲッティング / 脂質メッセンジャー / 赤血球寄生機構 / 阻害薬 / in gel kinase assay / 蛋白質脱燐酸化酵素 / 蛋白質燐酸化酵素 / マラリア / Plasmodium falciparum / Plasmodium / ネットワーク / リン酸化反応 / サイクリックAMP / イオンチャネル / キナーゼ / NO / カルモジュリン / ホスホリパーゼ / PAF / 長期増強 / 血小板活性化因子 / アラキドン酸 / リン酸化酵素 / カルシウムシグナル / 逆行性情報伝達 / 神経可塑性 Less

Identification and characterization of cellular senescence-specific genes
- Principal Investigator
  
  Kamada Shinji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor biology
- Research Institution
  Kobe University
細胞増殖制御におけるカスパーゼの役割
- Principal Investigator
  
  鎌田真司
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
Regulation mechanisms of mTOR-mediated nutrient signaling by protein phosphatase PP2APrincipal Investigator
- Principal Investigator
  
  KIKKAWA Ushio
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kobe University
mTORシグナルを介したがん抑制遺伝子TSCによる発がん機構の研究
- Principal Investigator
  
  YOSHINO Ken-ichi
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
アミノ酸バランスを感知するシグナル伝達機構と核酸生合成の研究
- Principal Investigator
  
  吉野健一
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Kobe University
蛋白質リン酸化酵素PKB/AktおよびPKCを介する細胞死と細胞周期の制御機構Principal Investigator
- Principal Investigator
  
  吉川潮
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
Study on the Mammalian target of rapamycin in thrombocytepoiesis, wound healing, and hyperlipemia
- Principal Investigator
  
  YOSHINO Ken-ichi, 米澤一仁
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kobe University
蛋白質リン酸化酵素PKB/AktおよびPKCを介する細胞死と細胞周期の制御機構Principal Investigator
- Principal Investigator
  
  吉川潮
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
Apoptotic dell death through lipid kinase/PKB/AFX and stress signaling pathwaysPrincipal Investigator
- Principal Investigator
  
  KIKKAWA Ushio
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kobe University
蛋白質リン酸化酵素PKB/AktおよびPKCを介する細胞死と細胞周期の制御機構Principal Investigator
- Principal Investigator
  
  吉川潮
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
細胞内情報伝達機構網の研究
- Principal Investigator
  
  西塚泰美
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Creative Basic Research
- Research Institution
  Kobe University
PHドメインを持つプロテインキナーゼPKBとHsp27との相互作用に関する研究Principal Investigator
- Principal Investigator
  
  吉川潮
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kobe University
PHドメイン結合物質によるPKB蛋白質リン酸化酵素の活性制御に関する研究Principal Investigator
- Principal Investigator
  
  吉川潮
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kobe University
Tyrosine phosphorylation and activation of PKC and its role in celluar regulationPrincipal Investigator
- Principal Investigator
  
  KIKKAWA Ushio
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kobe University
寄生各ステージにおけるマラリア原虫の蛋白質燐酸化、脱燐酸化酵素の解析と役割の検討
- Principal Investigator
  
  斎藤あつ子
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kobe University
Studies on intracellular signal transduction through phospholipase D
- Principal Investigator
  
  NAKAMURA Shun-ichi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kobe University
シグナル伝達におけるPHドメインと蛋白質リン酸化酵素活性制御領域の相互作用の解析Principal Investigator
- Principal Investigator
  
  吉川潮
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kobe University
一酸化窒素による蛋白質リン酸化酵素活性の制御機構に関する研究Principal Investigator
- Principal Investigator
  
  吉川潮
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Kobe University
シグナル伝達におけるPHドメインと蛋白質リン酸化酵素活性制御領域の相互作用の解析Principal Investigator
- Principal Investigator
  
  吉川潮
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kobe University
RESEARCH FOR MOLECULAR EVOLUTION OF PROTEIN KINASE C GENES OF PROTISTA EUGLENA GRACILIS ZAND ROLES OF THE KINASES.
- Principal Investigator
  
  OJI Yoshikiyo
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Plant nutrition/Soil science
- Research Institution
  KOBE UNIVERSITY
Regulation of the activity of protein kinases depending on their functional domainsPrincipal Investigator
- Principal Investigator
  
  KIKKAWA Ushio
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kobe University
中枢シナプスの逆行性情報伝達物質の探索
- Principal Investigator
  
  清水孝雄
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Studies on a protein-serine/threonine protein kinase family having a SH2 domainPrincipal Investigator
- Principal Investigator
  
  KIKKAWA Ushio
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kobe University
細胞内情報伝達機構網の研究
- Principal Investigator
  
  NISHIZUKA Yasutomi
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Creative Basic Research
- Research Institution
  Kobe University
Phospholipid degradation cascade and protein kinase C for intracellular signaling network.
- Principal Investigator
  
  NISHIZUKA Yasutomi
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kobe University
イノシトール燐脂質の代謝の調節とプロテイン・キナーゼCの活性化機構
- Principal Investigator
  
  NAKAMURA Shun-ichi
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kobe University
Properties of the delta-, epsilon-, and zeta- Subspecies of Protein Kinase CPrincipal Investigator
- Principal Investigator
  
  KIKKAWA Ushio
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kobe University
Construction and Application of Protein Kinase C Subspecies-specific Express ion Systems and Developmental Research for Screening of Selective Effectors
- Principal Investigator
  
  FUKAMI Yasuo
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kobe University, Laboratory of Molecular Biology
Protein Kinase Cの構造と機能、並びに細胞増殖の調節
- Principal Investigator
  
  西塚泰美
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kobe University
Studies on heterogeneity of protein kinase C, their structures, regulations and functions.
- Principal Investigator
  
  KISHIMOTO Akira
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kobe University
プロテインキナ-ゼCの特異的分子種発現細胞系の構築及びその選択的抑制剤の開発研究Principal Investigator
- Principal Investigator
  
  OGITA Kouji, 吉川潮
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kobe University
Protein Kinase Cの構造と機能,並びに細胞増殖の調節
- Principal Investigator
  
  西塚泰美
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kobe University
細胞成長因子の作用機構並びにその発がん遺伝子との関連の解析
- Principal Investigator
  
  西塚泰美
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Kobe University
MOLECULAR CLONING, CHARACTERIZATION, PREPARATION OF ANTIBODIES AND REGULATORS OF PROTEIN KINASE C
- Principal Investigator
  
  NISHIZUKA Yasutomi
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  General medical chemistry
- Research Institution
  KOBE UNIVERSITY
Study of protein kinase C : role in signal transduction and its disorder
- Principal Investigator
  
  NISHIZUKA Yasutomi
- Project Period (FY)
  1985 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kobe University School of Medicine

All 2015 2014 2013 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation

[Journal Article] Midostaurin preferentially attenuates proliferation of triple-negative breast cancer cell lines through inhibition of Aurora kinase family.2015
- Author(s)
  Kawai M., Nakashima A., Kamada S., and Kikkawa U.
- Journal Title
  
  J Biomed. Sci.
  
  Volume: 22 Issue: 1 Pages: 48-48
- DOI
  10.1186/s12929-015-0150-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26440053, KAKENHI-PROJECT-25640063
[Journal Article] Fission yeast arrestin-related trafficking adaptor, Arn1/Any1, is ubiquitinated by Pub1 E3 ligase and regulates endocytosis of Cat1 amino acid transporter.2014
- Author(s)
  Nakashima, A., Kamada, S., Tamanoi, F., and Kikkawa, U.
- Journal Title
  
  Biol. Open
  
  Volume: 3 Issue: 6 Pages: 542-552
- DOI
  10.1242/bio.20148367
- NAID
  120005460282
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25640063, KAKENHI-PROJECT-26440053
[Journal Article] Branched-chain amino acids enhance premature senescence through mammalian target of rapamycin complex I-mediated upregulation of p21 protein.2013
- Author(s)
  Nakano, M., Nakashima A., Nagano, T., Ishikawa, S., Kikkawa, U., and Kamada, S.
- Journal Title
  
  PLoS ONE
  
  Volume: 8 Issue: 11 Pages: e80411-e80411
- DOI
  10.1371/journal.pone.0080411
- NAID
  120005465549
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25640063
[Journal Article] A positive role of mammalian Tip41-like protein, TIPRL, in the amino-acid dependent mTORC1-signaling pathway through interaction with PP2A2013
- Author(s)
  Nakashima, A., Tanimura-Ito, K., Oshiro, N., Eguchi, S., Miyamoto, K., Momonami, A., Kamada, S., Kikkawa, U. and Yonezawa, K.
- Journal Title
  
  FEBS letter
  
  Volume: 587 Issue: 18 Pages: 2924-2929
- DOI
  10.1016/j.febslet.2013.07.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24770115, KAKENHI-PROJECT-25640063
[Journal Article] Cyclin I is involved in the regulation of cell cycle progression.2013
- Author(s)
  Nagano et al.
- Journal Title
  
  Cell Cycle
  
  Volume: 12 Issue: 16 Pages: 2617-2624
- DOI
  10.4161/cc.25623
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25290024, KAKENHI-PROJECT-25640063
[Journal Article] Contribution of caspase(s) to the cell cycle regulation at mitotic phase.2011
- Author(s)
  Hashimoto, T., Kikkawa, U., Kamada, S.
- Journal Title
  
  PLoS ONE 6(3)
- NAID
  120005465546
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390081
[Journal Article] Mammalian Tti1 and Tel2 are critical factors in mTOR complex assembly.2010
- Author(s)
  Kaizuka, T., Hara, T., Oshiro, N., Kikkawa, U., Yonezawa, K., Takehana, K., Iemura, S.I., Natsume, T., Mizushima, N.
- Journal Title
  
  J.Biol.Chem. 285(26)
  
  Pages: 20109-20116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390081
[Journal Article] Signal transducer and activator of transcription 3 upregulates interleukin-8 expression at the level of transcription in human melanoma cells.2010
- Author(s)
  Oka, M., Sakaguchi, M., Okada, T., Nagai, H., Ozaki, M., Yoshioka, T., Inoue, H., Mukaida, N., Kikkawa, U., Nishigori, C.
- Journal Title
  
  Exp.Dermatol. 19(8)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390081
[Journal Article] AMP-activated protein kinase phosphorylates glutamine : fructose-6-phosphate amidotransferase 1 at Ser243 to modulate its enzymatic activity.2009
- Author(s)
  Eguchi, S., Oshiro, N., Miyamoto, T., Yoshino, K., Okamoto, S., Ono, T., Kikkawa, U., Yonezawa, K.
- Journal Title
  
  Genes Cells 14(2)
  
  Pages: 179-189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390081
[Journal Article] Activation of mTORC1 in two steps : Rheb-GTP activation of catalytic function and increased binding of substrates to raptor.2009
- Author(s)
  Avruch, J., Long, X., Lin, Y., Ortiz-Vega, S., Rapley, J., Papageorgiou, A., Oshiro, N., Kikkawa, U.
- Journal Title
  
  Biochem.Soc.Trans. 37(1)
  
  Pages: 223-226
- Data Source
  KAKENHI-PROJECT-20390081
[Journal Article] AMP-activated protein kinase phosphorylates Golgi-specific brefeldin A resistance factor 1 at Thr1337 to induce disassembly of Golgi apparatus.2008
- Author(s)
  Miyamoto, T., Oshiro, N., Yoshino, K., Nakashima, A., Eguchi, S., Takahashi, M., Ono, Y., Kikkawa, U., Yonezawa, K.
- Journal Title
  
  J.Biol.Chem. 283(7)
  
  Pages: 4430-4438
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390081
[Journal Article] Possible involvement of caspase-7 in cell cycle progression at mitosis.2008
- Author(s)
  Hashimoto, T., Yamauchi, L., Hunter, T., Kikkawa, U., Kamada, S.
- Journal Title
  
  Genes Cells 13(6)
  
  Pages: 609-621
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390081
[Journal Article] The yeast Tor signaling pathway is involved in G2/M transition via polo-kinase.2008
- Author(s)
  Nakashima, A., Maruki, Y., Imamura, Y., Kondo, C., Kawamata, T., Kawanishi, I., Takata, H., Matsuura, A., Lee, K.S., Kikkawa, U., Ohsumi, Y., Yonezawa, K., Kamada, Y.
- Journal Title
  
  PLoS ONE 3(5)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390081
[Journal Article] Calcineurin- mediated dephosphorylation of c-Jun Ser-243 is required for c-Jun protein stability and cell transformation.2008
- Author(s)
  Huang, C.C, Wang, J.M., Kikkawa, U., Mukai, H., Shen, M.R., Morita, I., Chen, B.K., Chang, W.C.
- Journal Title
  
  Oncogene 27(17)
  
  Pages: 2422-2429
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390081
[Journal Article] The proline-Rich Akt substrate of 40 kDa (PRAS40) is a physiological substrate of mTOR complex 12007
- Author(s)
  Oshiro, N., Takahashi, R., Yoshino, K., Tanimura, K., Nakashima, A., Eguchi, S., Miyamoto, T., Hara, K., Takehana, K., Avruch, J., Kikkawa, U., Yonezawa, K.
- Journal Title
  
  J. Biol. Chem. 282(in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390094
[Journal Article] Different roles for the TOS and RAIP motifs of the translational regulator protein 4E-BP1 in the association with raptor and phosphorylation by mTOR in the regulation of cell size2006
- Author(s)
  Eguchi, S., Tokunaga, C., Hidayat, S., Oshiro, N., Yoshino, K., Kikkawa, U., Yonezawa, K.
- Journal Title
  
  Genes Cells 11 (7)
  
  Pages: 757-766
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390094
[Journal Article] Suppression of the mTOR-raptor signaling pathway by the inhibitor of heat shock protein 90 geldanamycin2006
- Author(s)
  Ohji, G., Hidayat, S., Nakashima, A., Tokunaga, C., Oshiro, N., Yoshino, K., Yokono, K., Kikkawa, U., Yonezawa, K.
- Journal Title
  
  J. Biochem. 139 (1)
  
  Pages: 129-135
- NAID
  10018848648
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390094
[Presentation] 新規細胞老化制御因子Dアミノ酸酸化酵素の機能解析2015
- Author(s)
  山尾俊介、長野太輝、吉川潮、鎌田真司
- Organizer
  第７４回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25640063
[Presentation] 減数分裂における分裂酵母TORC1の制御と機能2015
- Author(s)
  中嶋昭雄、山下郎、大坪瑶子、鎌田真司、瓜谷眞裕、山本正幸、吉川潮
- Organizer
  第３８回日本分子生物学会、第８８回日本生化学会　合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25640063
[Presentation] 細胞老化とアポトーシスの運命を決定する遺伝子の同定とその機能解析2013
- Author(s)
  長野　太輝、中野　真行、橋本　季明、江成　政人、吉川　潮、鎌田　真司
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25640063
[Presentation] 細胞老化制御に関与する遺伝子の同定と機能解析2013
- Author(s)
  大西　健悟、長野　太輝、山尾　俊介、中嶋　昭雄、吉川　潮、鎌田　真司
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25640063
[Presentation] Cyclin Iは細胞周期の進行に関与している2013
- Author(s)
  長野　太輝、橋本　季明、中嶋　昭雄、久永　眞市、吉川　潮、鎌田　真司
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25640063
[Presentation] Organization and closing remarks.2011
- Author(s)
  吉川潮
- Organizer
  2011 International Symposium on Cell Signaling and Gene Regulation.
- Place of Presentation
  National Cheng Kung University, Tainan, Taiwan
- Data Source
  KAKENHI-PROJECT-20390081
[Presentation] The signaling mechanisms through the protein phosphorylation reaction.2009
- Author(s)
  吉川潮
- Organizer
  2009 Japan-Taiwan Joint Symposium on Cell Signaling and Gene Regulation.
- Place of Presentation
  Kobe International Conference Center, Kobe, Japan,
- Data Source
  KAKENHI-PROJECT-20390081
[Presentation] Screening of novel caspase substrates functioning at mitotic phase.2009
- Author(s)
  橋本季明、吉田茂生、澤崎達也、遠藤弥重太、吉川潮、鎌田真司
- Organizer
  第32回日本分子生物学会年会(BMB2009)
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-20390081
[Presentation] Opening Remarks, The signaling mechanisms through the protein phosphorylation reaction2009
- Author(s)
  Kikkawa, U.
- Organizer
  2009 Japan-Taiwan Joint Symposium on Cell Signaling and Gene Regulation
- Place of Presentation
  Kobe International Conference Center, Kobe, Japan
- Year and Date
  2009-11-11
- Data Source
  KAKENHI-PROJECT-20390081
[Presentation] Identification of phosphoproteins in nutritional signaling by the combination of the immunoprecipitation using the phosphorylation-site specific antibody and mass fingerprinting analvsis.2008
- Author(s)
  Kikkawa, U.
- Organizer
  2008 International Symposium on Cell Signaling and Gene Regulation.
- Place of Presentation
  Tainan, Taiwan
- Year and Date
  2008-11-16
- Data Source
  KAKENHI-PROJECT-20390081
[Presentation] Identification of phosphoproteins in nutritional signaling by the combination of the immunoprecipitation using the phosphorylation-site specific antibody and mass fingerprinting analysis.2008
- Author(s)
  吉川潮
- Organizer
  2008 International Symposium on Cell Signaling and Gene Regulation
- Place of Presentation
  National Cheng Kung University, Tainan, Taiwan
- Data Source
  KAKENHI-PROJECT-20390081
[Presentation] The regulation of GFAT1 via AMPK signaling.2008
- Author(s)
  Eguchi, S., Oshiro, N., Miyamoto, T., Sasaki, T., Yonezawa, K., Kikkawa U.
- Organizer
  第60回日本細胞生物学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-20390081
[Presentation] カスパーゼの活性化阻害による細胞増殖の異常2008
- Author(s)
  橋本季明、吉川潮、鎌田真司
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会(BMB2010)
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-20390081
[Presentation] プロリン脱水素酵素（PRODH）は細胞老化誘導に関わる新規因子である
- Author(s)
  長野　太輝、山尾　俊介、吉川　潮、鎌田　真司
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜／パシフィコ横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25640063
[Presentation] プロリン脱水素酵素（PRODH）は細胞老化誘導に関わる新規因子である
- Author(s)
  長野　太輝、山尾　俊介、中嶋　昭雄、吉川　潮、鎌田　真司
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  横浜／パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25640063
[Presentation] 新規細胞老化誘導因子としてのDアミノ酸酸化酵素DAOの機能解析
- Author(s)
  山尾　俊介、長野　太輝、中嶋　昭雄、吉川　潮、鎌田　真司
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  横浜／パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25640063

1. OGITA Kouji (60204103)

# of Collaborated Projects: 10 results

# of Collaborated Products: 0 results
2. NISHIZUKA Yasutomi (10025546)

# of Collaborated Projects: 10 results

# of Collaborated Products: 0 results
3. KONISHI Hiroaki (40252811)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
4. KISHIMOTO Akira (60127363)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
5. KURODA Shun-ichi (60263406)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
6. NAKAMURA Shun-ichi (40155833)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
7. YAMAMOTO Toshiyoshi (00324939)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
8. KAMADA Shinji (20243214)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
9. YOSHINO Ken-ichi (90280792)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
10. OSHIRO Noriko (70372662)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
11. ASAOKA Yoshinori (20222565)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
12. FUKAMI Yasuo (00156746)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
13. MATSUZAKI Hidenori (80335463)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
14. TOUHARA Kazushige (00280925)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. SAKAI Norio (70263407)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. NAKASHIMA Akio (70397818)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
17. TACHIBANA Hideki (70126118)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
18. 井上圭三 (30072937)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
19. 小野功貴 (10243297)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
20. 山村博平 (90030882)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
21. 米澤一仁 (70283900)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
22. OJI Yoshikiyo (90031195)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. NANMORI Takashi (00180555)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. SUGIMOTO Toshio (70240851)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. YOSHIDA Kimihisa (50263372)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 清水孝雄 (80127092)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 飯野正光 (50133939)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 伊藤誠二 (80201325)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 山本長三郎 (50008231)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 藤澤仁 (10027039)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 渋木克栄 (40146163)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 田中千賀子 (20025571)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 斎藤あつ子 (00223131)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 斎藤尚亮 (60178499)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 向井秀幸 (80252758)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 横山光宏 (40135794)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 米原伸 (00124503)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 福井泰久 (00181248)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. 淀井淳司 (80108993)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. 徳永千春 (70335462)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
41. EGUCHI Satoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 鎌田振吉

# of Collaborated Projects: 0 results

# of Collaborated Products: 18 results

KIKKAWA Ushio 吉川 潮

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Regulation mechanisms of mTOR-mediated nutrient signaling by protein phosphatase PP2APrincipal Investigator

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蛋白質リン酸化酵素PKB/AktおよびPKCを介する細胞死と細胞周期の制御機構Principal Investigator

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蛋白質リン酸化酵素PKB/AktおよびPKCを介する細胞死と細胞周期の制御機構Principal Investigator

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Apoptotic dell death through lipid kinase/PKB/AFX and stress signaling pathwaysPrincipal Investigator

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蛋白質リン酸化酵素PKB/AktおよびPKCを介する細胞死と細胞周期の制御機構Principal Investigator

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PHドメインを持つプロテインキナーゼPKBとHsp27との相互作用に関する研究Principal Investigator

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PHドメイン結合物質によるPKB蛋白質リン酸化酵素の活性制御に関する研究Principal Investigator

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Tyrosine phosphorylation and activation of PKC and its role in celluar regulationPrincipal Investigator

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KIKKAWA Ushio 吉川潮