SAITO Naoaki 齋藤尚亮

… Alternative Names

斉藤尚亮サイトウナオアキ

齋藤尚亮サイトウナオアキ

斎藤尚亮

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Researcher Number	60178499
Other IDs
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Affiliation (based on the past Project Information) *help	2020: 神戸大学, バイオシグナル総合研究センター, 名誉教授 2016 – 2019: 神戸大学, バイオシグナル総合研究センター, 教授 2011 – 2015: 神戸大学, バイオシグナル研究センター, 教授 2012: 神戸大学, 自然科学系先端融合研究環バイオシグナル研究センター, 教授 2011: 神戸大学, 自然科学系先端融合研究環・バイオシグナル研究センター, 教授 … More 2008 – 2010: Kobe University, 自然科学系先端融合研究環バイオシグナル研究センター, 教授 2008: 神戸大学, 自然科学先端融合研究環バイオシグナル研究センター, 教授 1994 – 2008: 神戸大学, バイオシグナル研究センター, 教授 1994: 大阪大学, 医学部, 教授 1991 – 1993: Kobe Univ. Sch. Med., Associate Professor, 医学部, 講師 1992: 神戸大学, 医学部, 構師 1989 – 1990: Kobe Univ.Sch.Med., Dept. of Pharmacol., Research Associate, 医学部, 助手 1986 – 1987: 神戸大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator General pharmacology / Biological Sciences / General pharmacology / Biological Sciences / General medical chemistry / Neurochemistry/Neuropharmacology Except Principal Investigator General pharmacology / General pharmacology / Biological Sciences / Basic Section 47040:Pharmacology-related … More / Functional biochemistry / Neurochemistry/Neuropharmacology / Bioproduction chemistry/Bioorganic chemistry / Neurochemistry/Neuropharmacology / General physiology / Cerebral neurosurgery / General anatomy (including Histology/Embryology) / Science and Engineering Less
Keywords	Principal Investigator プロテインキナーゼC / GFP / 遺伝子操作動物 / トランスロケーション / イメージング / サブタイプ / 脱リン酸化 / リン酸化 / トランスポーター / モデル動物 … More / 神経可塑性 / カルシウム / 変異体 / 長期増強 / protein kinase C / 脂質 / リン酸化酵素 / 遺伝子解析 / モデルマウス / 難聴 / 内耳 / アミロイド / 創薬 / パーキンソン病 / 脊髄小脳変性症 / 遺伝子変異 / 神経変性 / ライブイメージング / Rac / 活性酸素 / ファゴサイトーシス / ターゲティング / トランスジェニックマウス / セラミド / green fluorescent protein / ジアシルグリセロールキナーゼ / ホルボールエステル / セロトニン / グリア細胞 / グルタミン酸 / synapse / transporter / Hspファミリー / ischemia / Spinocerebellar ataxia / NADPH oxidase / phagocytosis / diacylglycerol kinase / lipid / live imaging / カスケード / 脂質メッセンジャー / 凝集体形成 / 核移行 / 細胞周期 / ジアシルグリセロール / 虚血 / 小脳脊髄変性症 / NADPHオキシダーゼ / ドン食作用 / transgenic mice / apoptosis / subtype / targeting / 可視化 / 細胞死 / reporter assay / promoter / mode disorder / polymorphism / Genomic analysis / serotonin transporter / レポーターアッセイ / プロモーター / 気分・不安性障害 / 遺伝子多型 / セロトニントランスポーター / electron microscopy / depression / phosphorylation / interferon / serotonin / COS-7細胞 / 電子顕微鏡 / シナプス / うつ病 / インターフェロン / ケラチノサイト / 分化誘導因子 / 脂肪細胞 / ドーパミン / 質量分析 / リン酸化プロテオーム / 治療薬 / アクチン / 有毛細胞 / Cdc42 / オートファジー / 乳幼児 / 遺伝子異常 / oxidase / NADPH / p40phox / クローン病 / 平衡覚 / 聴覚 / cdc42 / 細胞内情報伝達 / 神経変性疾患 / プロテインキナーゼ / 精髄小脳変性症 / 性ホルモン / 神経 / グリア / 脳虚血 / コンフォーカルレーザースキャン蛍光顕微鏡 / テトラサイクリン制御 / 活性酵素 / マクロファージ / 長期抑圧 / シルグリセロールキナーゼ / 発癌 / DGキナーゼ / green fluourescent protein / ジアルシルグリセロールキナーゼ / DNAマイクロアレイ / ノックアウトマウス / グルタミン酸トランスポーター / てんかん / ATP受容体 / 脂肪酸 / 培養細胞 / コンフォーカル顕微鏡 / クロライド / ナトリウム / phosphorylatim / GABA / シナプトゾーム / アフリカツメガエル卵母細胞 / GABAトランスポーター … More Except Principal Investigator プロテインキナーゼC / サブタイプ / プロテインキナ-ゼC / GFP / ジアシルグリセロールキナーゼ / ホルボールエステル / PKC / Calcineurin / 免疫組織化学 / Cloning / クローニング / Protein kinase C / NMR / リン酸化 / PC12 / translocation / cChAT / pChAT / C1 domain / C1ドメイン / protein kinase C / diacylglycerol kinase / CD-38 / immediate early gene / FK506 / カルシニューリン / Protein Kinase / cDNAクロ-ニング / カルシニュ-リン / 脱燐酸化反応 / 蛋白質燐酸化反応 / Protein Kinase C / 細胞内情報伝達 / プロティンキナーゼC / Tet制御システム / プイロテインキナーゼC / 小脳プルキンエ細胞 / 神経可塑性 / トランスジェニックマウス / 蛋白質リン酸化 / インドラクタム / 発がんプロモーター / 低分子量G蛋白質 / ホスホリパーゼA / 構造解析 / シナプス前部 / 脊髄後角 / 電子顕微鏡 / 分子種 / in situ hybridization / CSP alpha / リン酸化抗体 / CSPalpha / シャペロン / HSP70 / AAV / プレシナプス / アデノ随伴ウイルス / CSPa / パーキンソン病 / 活性酸素種 / 聴力 / 内耳有毛細胞 / Rac / Rho-family GTPase / アクチン / DIAPH1 / RhoA / Cdc42 / 遺伝性難聴 / 感音難聴 / DFNA1 / DIA1 / 耳石 / 聴毛 / 平衡覚 / 聴覚 / Electron microscopy / Immunocytochemistry / Central nervous system / Subspecies / 中枢神経系 / クロ-ニング / noradrenaline / Acetylcholine / neurotransmitter release / outradiography / immunohistochemistry / pProtein kinase C / 免疫相織化学 / γ-アミノ酪酸 / ノルアドレナリン / アセチルコリン / 神経伝達物質遊離 / オートラジオグラフィー / subtype cAMP-dependent protein kinase / Protein kinaseC / molecular biology / Neuropeptide / Dopamine / 組換えDNA / in situ mRNA cDNA hybridization / ノザーンブロット / アンギオテンシノーゲンcDNA / アンギオテンシノーゲン / 制御サブユニット / サイクリックAMP依存生蛋白質燐酸化酵素 / 遺伝子工学 / ニューロペプチド / ドパミン / Ceramide / Lipid messenger / Fatty acid / Diacylglycerol kinase / DGK / セラミド / 脂質シグナル / 脂肪酸 / HEK293 / トランスロケーション / bChAT / HEK-293 / tumor promoter / phorbol ester / indolactam / bryostatin / aplysiatoxin / indolactam-V / Unc13 / chimaerin / RasGRP / 亜鉛フィンガー / プロテインキナーゼ C / ブライオスタチン / C1 ドメイン / アプリシアトキシン / Purkinje cells / tet-regulated / neural plasticity / phosphorylation / transgenio mice / 小脳プリキンエ細胞 / Xenopus oocytes / Astrocyte / Facilitation of neurotransmission / Hippocampus / GLT-1 glutamate transporter / A_<2a> adenosine receptor / Adenosine / 興奮性シナプス後電位 / 卵母細胞膜発現モデル / 神経膠細胞 / シナプス伝達促進 / 海馬 / GLT-1グルタミン酸輸送担体 / A_<2a>アデノシン受容体 / アデノシン / Electroporation / HUVEC / Blood-brain Barrier / Neuronal Transplantation / In vivo gene transfer / 細胞移植 / 脳虚血 / 神経細胞死 / 遺伝子導入 / グルタミン酸トランスポーター / CaM kinase IV / nuclear import factor / membranous undercoat / membranous caveolae / カベオレ / 核内遺伝子発現 / プロティンホスファターゼ / プロティンキナーゼ / 細胞骨格 / gap-junction / 核膜孔ターゲッチング複合体 / カルモジュリンキナーゼIV / カベオラ / コネクシン / CaMキナーゼIV / 核移行 / 膜裏うち蛋白 / CD38 / 細胞膜カベオラ / Neural visinin-like calcium-binding proteins / Endocytosis / Lipid kinase / Adaptin / Long-term potentiation / GABA transporter / 脱燐酸化酵素阻害薬 / カリクリン-A / cDNAクローニング / NVP-1 / visinin / カルシウム動員 / NG108-15細胞 / CA1 / セロトニン遊離 / カリクリンA / オカダ酸 / Ca^<2+>結合蛋白質 / エンドサイトーシス / リピットキナーゼ / アダプチン / 長期増強 / GΛT / NVP / Protein phosphatase / Subtype / Expression / GABA_B receptor / Protein Kinase A / 大量発現 / プロテインフォスファターゼ / 発現 / GABA_B受容体 / プロテインキナーゼA / プロテインキナーゼ / cDNA Cloning / Neurotransmitter / Synapse Formation / Dephosphorylation / Protein Phosphorylation / 神経細胞 / 蛋白質脱燐酸化酵素 / 蛋白質燐酸化酵素 / 神経伝達物質 / シナプス形成 / プロテインキナ-ゼ / Differentiation / Lysolecithin / Phospholipase A2 / Phospholipase C / Diacylglycerol / Calcium / Signal Transduction / イノシトールリン脂質 / 細胞増殖 / ホルボ-ルエステル / イノシト-ルリン脂質 / カルシウムイオン / ホスホリパ-ゼA2 / ホスホリパ-ゼC / ジアシルグリセロ-ル / 細胞分化 / リゾレシチン / ホスホリパーゼA2 / ホスホリパーゼC / ジアシルグリセロール / カルシウム / ニトロシル化 / ベータ３アドレナリン受容体 / パルミトイル化 / 貧食細胞 / トランスポートソーム / 貪食細胞 / 活性酸素 / NADPH oxidase / 膜輸送 / 蛋白質 / 脂質 / シグナル伝達 / 共焦点顕微鏡 / 可視化 / 膜蛋白 / 抗体療法 / 抗体 / 膜タンパク / DNA vaccination / ライブイメージング / コンホメーション / システインリッチドメイン / 一酸化窒素合成酵素 / チオレドキシン / 核局在化シグナル / ホスファチジルイノシトール3キナーゼ / ストレス / NO(一酸化窒素) / Fas / PI 3キナーゼ / 核-細胞質間物質輸送 / PKC(プロテインキナーゼC) / PLC(ホスホリパーゼC) / PLD(ホスホリパーゼD) / PAF-アセチルヒドロラーゼ / 創薬 / 情報伝達機構網 / チロシンキナーゼ / mTOR / アミノ酸バランス / CG-NAP / PKN / ターゲッティング / 脂質メッセンジャー / 燐酸化反応 / GAP-43 / 可塑性 / 免疫電顕 / NMDA受容体 / グルタミン酸 / 特異抗体 / サブスタンスP Less

Development of a novel treatment for Parkinson's disease focusing on the protective effect of CSPa phosphorylation on synaptic terminal
- Principal Investigator
  
  Shirafuji Toshihiko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Kobe University
Elucidation of amyloid formation mechanism in Spinocerebellar ataxia and its application to drug therapyPrincipal Investigator
- Principal Investigator
  
  SAITO NAOAKI
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
Elucidation of a new differentiation mechanism of beige adipocytes and its application for drug designPrincipal Investigator
- Principal Investigator
  
  SAITO NAOAKI
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
Roles of Rho-family small GTPases in establishment and maintenance for hearing and balancing
- Principal Investigator
  
  Ueyama Takehiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
聴・平衡覚器官のイメージング解析～１分子から個体レベルまで～Principal Investigator
- Principal Investigator
  
  齋藤尚亮
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
Determination of PKC substrate involved in neurodegenerative diseases and its application for drug designPrincipal Investigator
- Principal Investigator
  
  SAITO NAOAKI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
Analysis of protein Cysteome modification in G protein-coupled receptor
- Principal Investigator
  
  ADACHI Naoko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
聴・平衡覚器官のイメージング解析～１分子から個体レベルまで～Principal Investigator
- Principal Investigator
  
  齋藤尚亮
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
Roles of p40phox in Crohn disease and its application for drug developmentPrincipal Investigator
- Principal Investigator
  
  SAITOU Naoaki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
Production and analysis of model animals for neurodegenerative diseases caused by dysfunction of PKC and their use for drug designPrincipal Investigator
- Principal Investigator
  
  SAITO Naoaki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
貪食細胞における活性酸素産生トランスポートソームの形成・活性化機構の解明
- Principal Investigator
  
  上山健彦
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
Mechanism and treatment for the disease caused by the impairment of PKC signalingPrincipal Investigator
- Principal Investigator
  
  SAITO Naoaki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
性ホルモンの神経保護作用におけるグリア・ニューロン内情報伝達クロストーク機構Principal Investigator
- Principal Investigator
  
  齋藤尚亮
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
脳部位・時期特異的な蛋白質発現マウスを用いた神経情報伝達機構のイメージング解析Principal Investigator
- Principal Investigator
  
  齋藤尚亮
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
核内脂質シグナル及び核移行蛋白質の可視化システムを用いた細胞周期制御機構の解明
- Principal Investigator
  
  白井康仁
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
Molecular mechanism of cellular response induced by dynamic metabolism of membrane phospholipidPrincipal Investigator
- Principal Investigator
  
  SAITO Naoaki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
小脳長期抑圧現象におけるプロテインキナーゼCおよびDGキナーゼの時空間解析Principal Investigator
- Principal Investigator
  
  齋藤尚亮
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
活性酸素産生機構における脂質シグナルのダイナミックイメージング解析Principal Investigator
- Principal Investigator
  
  齋藤尚亮
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
DNA Vaccinationによる膜機能蛋白に対する抗体作成
- Principal Investigator
  
  TANIGUCHI Taizo
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
PKCターゲティングのFRETによる抗癌剤のハイスループットスクリーニングの開発Principal Investigator
- Principal Investigator
  
  齋藤尚亮
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
Development of new agents that regulate cellular signal transduction
- Principal Investigator
  
  OHIGASHI Hajime
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  KYOTO UNIVERSITY
Analysis of intracellular translocation of choline acetyltransferase by bioimaging
- Principal Investigator
  
  MATSUO Akinori
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Shiga University of Medical Science
Analysis of higher structure of fatty aid -responsible domains in PKC and DGK
- Principal Investigator
  
  SHIRAI Yasuhito
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kobe University
CキナーゼとDGキナーゼの神経情報伝達におけるクロストーク機構のイメージング解析Principal Investigator
- Principal Investigator
  
  齋藤尚亮
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
発がんプロモーションのメカニズム解明のための鍵化合物の開発と応用
- Principal Investigator
  
  IRIE Kazuhiro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Kyoto University
神経可塑性制御に対するPKCの役割-トランスジェニックマウスを用いた研究-
- Principal Investigator
  
  酒井規雄
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hiroshima University
  Kobe University
CキナーゼとDGキナーゼの神経情報伝達におけるクロストーク機構の解析Principal Investigator
- Principal Investigator
  
  齋藤尚亮
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
Spatio-temporal signaling mechanism of protein kinase CPrincipal Investigator
- Principal Investigator
  
  SAITO Naoaki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  KOBE UNIVERSITY
CキナーゼとDGキナーゼの神経情報伝達におけるクロストーク機構の解析Principal Investigator
- Principal Investigator
  
  斎藤尚亮
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
DNAマイクロアレイを利用したてんかん治療薬の新規標的分子の検索Principal Investigator
- Principal Investigator
  
  斎藤尚亮
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
Pharmacogenomic research for mood disorderPrincipal Investigator
- Principal Investigator
  
  SAITO Naoaki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kobe University
Studies on neural plasticity using transgenic mice expressing GFP-tagged PKC
- Principal Investigator
  
  SAKAI Norio
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kobe University
細胞内情報伝達機構網の研究
- Principal Investigator
  
  NISHIZUKA Yasutomi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Creative Basic Research
- Research Institution
  Kobe University
ADENOSINE FACILITATES HIPPOCAMPAL NEUROTRANSMISSION BY BLOCKING GLIAL GLUTAMATE REUPTAKE VIA THE GLUTAMATE TRANSPORTER GLT-1
- Principal Investigator
  
  NISHIZAKI Tomoyuki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  HYOGO COLLEGE OF MEDICINE
  Kobe University
GFP標識プロテインキナーゼC遺伝子改変マウスの作製とその神経可塑性研究への応用Principal Investigator
- Principal Investigator
  
  斎藤尚亮
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kobe University
プロテインキナーゼCサブタイプの活性化とターゲッティング機構の関連に関する研究Principal Investigator
- Principal Investigator
  
  斎藤尚亮
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kobe University
Na^+/Cl^-依存性トランスポーターの分子間相互作用と機能協関する蛋白質の検索Principal Investigator
- Principal Investigator
  
  斎藤尚亮
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kobe University
蛍光標識プロテインキナーゼCの遺伝子改変マウスの作製とその神経可塑性研究への応用Principal Investigator
- Principal Investigator
  
  斎藤尚亮
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kobe University
Protection of Neuronal Death by Induction of Glutamate Transporter Gene
- Principal Investigator
  
  KONDOH Takeshi
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kobe University School of Medicine
Research for modulation of expression of serotonin transporter and its involvement in mental disorderPrincipal Investigator
- Principal Investigator
  
  SAITO Naoaki
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  KOBE UNIVERSITY
長期増強現象におけるグルタミン酸トランスポーターの制御機構に関する研究Principal Investigator
- Principal Investigator
  
  斎藤尚亮
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kobe University
グリア細胞に存在するグルタミン酸トランスポーターの長期増強における役割の解明Principal Investigator
- Principal Investigator
  
  斎藤尚亮
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
Molecular biological and morphological analysis of signal transduction mechanism from membrane to nuchreos
- Principal Investigator
  
  KONDO Hisatake
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Tohoku University
燐酸化による神経伝達物質トランスポーター機能制御と長期増強との関係に関する研究Principal Investigator
- Principal Investigator
  
  斎藤尚亮
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
脊髄後角におけるCキナーゼ各分子種とグルタミン酸受容体の関係についての研究
- Principal Investigator
  
  田中千賀子
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kobe University
プロテインキナーゼCによる神経伝達物質トランスポーター機能の制御機構に関する研究Principal Investigator
- Principal Investigator
  
  斎藤尚亮
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
Screening of drugs for neurodegenerative disorders using neurotransmitter release machinery expressed in Xenopus oocytes
- Principal Investigator
  
  SHUNTOH Hisato
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
痛覚伝導機構におけるプロテインキナーゼCの役割
- Principal Investigator
  
  田中千賀子
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kobe University
シナプス伝達の長期増強におけるグルタミン酸受容体とプロテインキナーゼCの役割
- Principal Investigator
  
  田中千賀子
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kobe University
痛覚伝導機構におけるプロテインキナ-ゼCの役割
- Principal Investigator
  
  TANAKA Chikako
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kobe University
Establishment of cell lines which specifically express a subtype of protein kinases and protein phosphatases and its application
- Principal Investigator
  
  TANAKA Chikako
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University School of Medicine
The Role of Protein Phosphorylation and dephosphorylation in Neuronal Signal Transduction
- Principal Investigator
  
  TANAKA Chikako
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
Signal Transduction Via Protein Kinase C Pathway
- Principal Investigator
  
  NISHIZUKA Yasutomi
- Project Period (FY)
  1989 – 1992
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Research Institution
  Kobe University
Electron microscopic immunocytochemistry of protein kinase C using subspecies-specific anti-peptide antibody
- Principal Investigator
  
  TANAKA Chikako
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University School of Medicine
Molecular biologocal studies on the regulation of neuropeptide synthesis by dopamine
- Principal Investigator
  
  TNAKA Chikako
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University
Studies on the role of protein kinase C
- Principal Investigator
  
  TANIYAMA Kohtaro
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kobe University

[Book] 実験医学別冊「染色・バイオイメージング実験ハンドブック」2006
- Author(s)
  斎藤尚亮
- Total Pages
  334
- Publisher
  羊土社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390065
[Journal Article] Rac-Dependent Signaling from Keratinocytes Promotes Differentiation of Intradermal White Adipocytes2020
- Author(s)
  Ueyama Takehiko、Sakuma Megumi、Nakatsuji Mio、Uebi Tatsuya、Hamada Takeshi、Aiba Atsu、Saito Naoaki
- Journal Title
  
  Journal of Investigative Dermatology
  
  Volume: 140 Issue: 1 Pages: 75-84.e6
- DOI
  10.1016/j.jid.2019.06.140
- NAID
  120006733143
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22472, KAKENHI-PROJECT-17H04032, KAKENHI-PROJECT-17H04042
[Journal Article] mTORC1 is involved in DGKβ-induced neurite outgrowth and spinogenesis.2020
- Author(s)
  Nakai, H., Tsumagari, R., Maruo, K., Nakashima, A., Kikkawa, U., Ueda, S., Yamanoue, M., Saito, N., Takei, N., Shirai, Y.
- Journal Title
  
  Neurochem. Int.
  
  Volume: 134
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04032
[Journal Article] Spinocerebellar ataxia type 14 caused by a nonsense mutation in the PRKCG gene2019
- Author(s)
  Shirafuji Toshihiko、Shimazaki Haruo、Miyagi Tatsuhiro、Ueyama Takehiko、Adachi Naoko、Tanaka Shigeru、Hide Izumi、Saito Naoaki、Sakai Norio
- Journal Title
  
  Molecular and Cellular Neuroscience
  
  Volume: 98 Pages: 46-53
- DOI
  10.1016/j.mcn.2019.05.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06700, KAKENHI-PROJECT-18K06891, KAKENHI-PROJECT-18K07392, KAKENHI-PROJECT-19K22472, KAKENHI-PROJECT-17H04042, KAKENHI-PROJECT-19H03409
[Journal Article] Differential S-palmitoylation of the human and rodent β3-adrenergic receptors.2019
- Author(s)
  Adachi N, Hess DT, Kaku M, Ueda C, Numa C, Saito N.
- Journal Title
  
  J Biol Chem.
  
  Volume: 15;294(7) Issue: 7 Pages: 2569-2578
- DOI
  10.1074/jbc.ra118.004978
- NAID
  120006604674
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08595, KAKENHI-PROJECT-17H04032
[Journal Article] Spinocerebellar ataxia type 14 caused by a nonsense mutation in the PRKCG gene2019
- Author(s)
  Shirafuji T, Shimazaki H, Miyagi T, Ueyama T, Adachi N, Tanaka T, Hide I, Saito S, Sakai S
- Journal Title
  
  Mol. Cell. Neurosci.
  
  Volume: 98 Pages: 46-53
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04032
[Journal Article] Pharmacological induction of heat shock proteins ameliorates toxicity of mutant PKCγ in spinocerebellar ataxia type 142018
- Author(s)
  Nakazono, A., Adachi, N., Takahashi, H., Seki, T., Hamada, D., Ueyama, T., Sakai, N. and Saito, N.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 293 Issue: 38 Pages: 14758-14774
- DOI
  10.1074/jbc.ra118.002913
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05133, KAKENHI-PROJECT-17H04032, KAKENHI-PROJECT-17H04042, KAKENHI-PROJECT-16K08276, KAKENHI-PROJECT-16K15318
[Journal Article] Hearing vulnerability after noise exposure in a mouse model of reactive oxygen species overproduction2018
- Author(s)
  Morioka Shigefumi、Sakaguchi Hirofumi、Yamaguchi Taro、Ninoyu Yuzuru、Mohri Hiroaki、Nakamura Takashi、Hisa Yasuo、Ogita Kiyokazu、Saito Naoaki、Ueyama Takehiko
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: 146 Issue: 4 Pages: 459-473
- DOI
  10.1111/jnc.14451
- NAID
  120006545101
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04032, KAKENHI-PROJECT-17H04042, KAKENHI-PROJECT-16K08288
[Journal Article] The Role of Cysteine String Protein Alpha (CSPα) Phosphorylation at Serine 10, and 34, by Protein Kinase Cγ for Presynaptic Maintenance.2018
- Author(s)
  Shirafuji T, Ueyama T, Adachi N, Yoshino KI, Sotomaru Y, Uwada J, Kaneoka A, Ueda T, Tanaka S, Hide I, Saito N, Sakai N
- Journal Title
  
  J. Neurosci.
  
  Volume: 38 Issue: 2 Pages: 278-290
- DOI
  10.1523/jneurosci.1649-17.2017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08234, KAKENHI-PROJECT-16K19012, KAKENHI-PROJECT-17H04032, KAKENHI-PROJECT-17H04042, KAKENHI-PROJECT-15K09317, KAKENHI-PROJECT-18K06891, KAKENHI-PROJECT-16H05133, KAKENHI-PROJECT-16K15318
[Journal Article] Roles of Cdc42 and Rac in Bergmann glia during cerebellar corticogenesis. Exp. Neurol.2018
- Author(s)
  Sakamoto I, Ueyama T, Hayashibe M, Nakamura T, Mohri H, Kiyonari H, Shigyo M, Tohda C, Saito N.
- Journal Title
  
  Exp. Neurol.
  
  Volume: 302 Pages: 57-67
- DOI
  10.1016/j.expneurol.2017.12.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03558, KAKENHI-PROJECT-17H04042, KAKENHI-PROJECT-17H04032
[Journal Article] Golgi-Associated Protein Kinase C-ε Is Delivered to Phagocytic Cups: Role of Phosphatidylinositol 4-Phosphate2017
- Author(s)
  Hanes Cheryl M.、D’Amico Anna E.、Ueyama Takehiko、Wong Alexander C.、Zhang Xuexin、Hynes W. Frederick、Barroso Margarida M.、Cady Nathaniel C.、Trebak Mohamed、Saito Naoaki、Lennartz Michelle R.
- Journal Title
  
  J. Immunol
  
  Volume: 199 Issue: 1 Pages: 271-277
- DOI
  10.4049/jimmunol.1700243
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04032, KAKENHI-PROJECT-17H04042
[Journal Article] Validation of Anti-CSPα, SNAP25, Tyrosine Hydroxylase, Ubiquitin, Cleaved Caspase 3, and pSer PKC Motif Antibodies for Utilization in Western Blotting2017
- Author(s)
  Shirafuji T, Ueyama T, Tanaka S, Hide I, Saito N and Sakai N
- Journal Title
  
  ACTA HISTOCHEMICA ET CYTOCHEMICA
  
  Volume: 50 Issue: 6 Pages: 177-180
- DOI
  10.1267/ahc.17028
- NAID
  130006285168
- ISSN
  0044-5991, 1347-5800
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08234, KAKENHI-PROJECT-16K15318, KAKENHI-PROJECT-16H05133, KAKENHI-PROJECT-17H04032, KAKENHI-PROJECT-17H04042, KAKENHI-PROJECT-15K09317
[Journal Article] Novel role of Rac-Mid1 signaling in medial cerebellar development.2017
- Author(s)
  Nakamura T, Ueyama T, Ninoyu Y, Sakaguchi H, Choijookhuu N, Hishikawa Y, Kiyonari H, Kohta M, Sakahara M, de Curtis I, Kohmura E, Hisa Y, Aiba A, Saito N.
- Journal Title
  
  Development
  
  Volume: 144 Issue: 10 Pages: 1863-1875
- DOI
  10.1242/dev.147900
- NAID
  120006363303
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08471, KAKENHI-PLANNED-25115010, KAKENHI-PROJECT-17H04032, KAKENHI-PROJECT-17H04042
[Journal Article] A novel Rac1-GSPT1 signaling pathway controls astrogliosis following central nervous system injury2017
- Author(s)
  Ishii T, Ueyama T, Shigyo M, Kohta M, Kondoh T, Kuboyama T, Uebi T, Hamada T, Gutmann DH, Aiba A, Kohmura E, Tohda C, Saito N
- Journal Title
  
  J Biol Chem
  
  Volume: 292 Issue: 4 Pages: 1240-1250
- DOI
  10.1074/jbc.m116.748871
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460340, KAKENHI-PROJECT-17H03558, KAKENHI-PROJECT-17H04032
[Journal Article] Loss of the Phenolic Hydroxyl Group and Aromaticity from the Side Chain of Anti-Proliferative 10-Methyl-aplog-1, a Simplified Analog of Aplysiatoxin, Enhances Its Tumor-Promoting and Proinflammatory Activities2017
- Author(s)
  Yusuke Hanaki, Masayuki Kikumori, Harukini Tokuda, Mutsumi Okamura, Shingo Dan, Naoko Adachi, Naoaki Saito, Ryo C. Yanagita, Kazuhiro Irie
- Journal Title
  
  Molecules
  
  Volume: 22 Issue: 4 Pages: 631-631
- DOI
  10.3390/molecules22040631
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16J04817, KAKENHI-PROJECT-16H05105, KAKENHI-PROJECT-17H04032, KAKENHI-PROJECT-16H06276
[Journal Article] Constitutive activation of DIA1 (DIAPH1) via C-terminal truncation causes human sensorineural hearing loss.2016
- Author(s)
  Ueyama T, Ninoyu Y, Nishio S, Miyoshi T, Torii H, Nishimura K, Sugahara K, Sakata H, Thumkeo D, Sakaguchi H, Watanabe N, Usami S, Saito N, Kitajiri S.
- Journal Title
  
  EMBO Molecular Medicine
  
  Volume: 8 Issue: 11 Pages: 1310-1324
- DOI
  10.15252/emmm.201606609
- NAID
  120005850206
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02565, KAKENHI-PROJECT-16J09300, KAKENHI-PROJECT-26293369, KAKENHI-PROJECT-26460340, KAKENHI-PROJECT-15K10753
[Journal Article] Essential role of constitutive androstane receptor in Ginkgo biloba extract induced liver hypertrophy and hepatocarcinogenesis2015
- Author(s)
  Maeda J, Inoue K, Ichimura R, Takahashi M, Kodama Y, Saito N, Yoshida M.
- Journal Title
  
  Food Chem Toxicol.
  
  Volume: 83 Pages: 201-209
- DOI
  10.1016/j.fct.2015.06.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26670124, KAKENHI-PROJECT-25293060
[Journal Article] Identification and characterization of PKCγ, a kinase associated with SCA14, as　an amyloidogenic protein.2015
- Author(s)
  Takahashi H, Adachi N, Shirafuji T, Danno S, Ueyama T, Vendruscolo M, Shuvaev AN, Sugimoto T, Seki T, Hamada D, Irie K, Hirai H, Sakai N, *Saito N.
- Journal Title
  
  Hum Mol Genet.
  
  Volume: 24 Issue: 2 Pages: 525-539
- DOI
  10.1093/hmg/ddu472
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-25113715, KAKENHI-PROJECT-25293060, KAKENHI-PROJECT-25430065, KAKENHI-PROJECT-26460340, KAKENHI-PROJECT-26670124, KAKENHI-PROJECT-26440076, KAKENHI-PROJECT-25293061
[Journal Article] The Extracellular A-loop of Dual Oxidases Affects the Specificity of Reactive Oxygen Species Release.2015
- Author(s)
  Ueyama T, Sakuma M, Ninoyu Y, Hamada T, Dupuy C, Geiszt M, Leto TL, Saito N.
- Journal Title
  
  J Biol. Chem
  
  Volume: 290 Issue: 10 Pages: 6495-6506
- DOI
  10.1074/jbc.m114.592717
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-25113715, KAKENHI-PROJECT-26460340, KAKENHI-PROJECT-26670124, KAKENHI-PROJECT-25293060
[Journal Article] Diacylglycerol kinase as a possible therapeutic target for neuronal diseases.2014
- Author(s)
  Shirai, Y and Saito, N
- Journal Title
  
  Journal of Biomedical Science
  
  Volume: 21 Pages: 28-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293060
[Journal Article] Maintenance of stereocilia and apical junctional complexes by Cdc42 in cochlear hair cells,2014
- Author(s)
  Ueyama, T., Sakaguchi, H., Nakamura, T., Goto, A., Morioka, S., Shimizu, A., Nakao, K., Hishikawa, Y., Ninoyu, Y., Kassai, H., Suetsug, J., Koji, T., Fritzsch, B., Yonemura, S., Hisa, Y., Matsuda, M., Aiba, A., and Saito, N.
- Journal Title
  
  J. Cell Science
  
  Volume: 印刷中
- NAID
  120006986582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293060
[Journal Article] Maintenance of stereocilia and apical junctional complexes by Cdc42 in cochlear hair cells,2014
- Author(s)
  Ueyama, T., Sakaguchi, H., Nakamura, T., Goto, A., Morioka, S., Shimizu, A., Nakao, K., Hishikawa, Y., Ninoyu, Y., Kassai, H., Suetsug, J., Koji, T., Fritzsch, B., Yonemura, S., Hisa, Y., Matsuda, M., Aiba, A., and Saito, N.
- Journal Title
  
  J. Cell Science
  
  Volume: 印刷中
- NAID
  120006986582
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25113715
[Journal Article] Deregulation of the actin cytoskeleton and macropinocytosis in response to phorbol ester by the mutant protein kinase C gamma that causes spinocerebellar ataxia type 14.2014
- Author(s)
  Yamamoto K, Seki T, Yamamoto H, Adachi N, Tanaka S, Hide I, Saito N, Sakai N
- Journal Title
  
  Front Physiol.
  
  Volume: 5 Pages: 126-126
- DOI
  10.3389/fphys.2014.00126
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590321, KAKENHI-PROJECT-24591264, KAKENHI-PROJECT-24659117, KAKENHI-PROJECT-24790252, KAKENHI-PUBLICLY-25113715, KAKENHI-PROJECT-25293060, KAKENHI-PROJECT-25293061, KAKENHI-PROJECT-25430065
[Journal Article] Maintenance of stereocilia and apical junctional complexes by Cdc42 in cochlear hair cells2014
- Author(s)
  Ueyama T, Sakaguchi H, Nakamura T, Goto A, Morioka S, Shimizu A, Nakao K, Hishikawa Y, Ninoyu Y, Kassai H, Suetsugu S, Koji T, Fritzsch B, Yonemura S, Hisa Y, Matsuda M, Aiba A, Saito N.
- Journal Title
  
  J Cell Sci.
  
  Volume: 127 Pages: 2040-2052
- DOI
  10.1242/jcs.143602
- NAID
  120006986582
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590255, KAKENHI-PUBLICLY-25113715, KAKENHI-PROJECT-25293060, KAKENHI-PROJECT-26291037, KAKENHI-PROJECT-26460340, KAKENHI-PROJECT-26670124
[Journal Article] Diacylglycerol kinase as a possible therapeutic target for neuronal diseases.2014
- Author(s)
  Shirai, Y and Saito, N
- Journal Title
  
  Journal of Biomedical Science
  
  Volume: 21 Pages: 28-36
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25113715
[Journal Article] Heparin inhibits melanosome uptake and inflammatory response coupled with phagocytosis through blocking PI3k/Akt and MEK/ERK signaling pathways in human epidermal keratinocytes.2014
- Author(s)
  Makino-Okamura C, Niki Y, Takeuchi S, Nishigori C, Declercq L, Yaroch DB, Saito N.
- Journal Title
  
  Pigment Cell Melanoma Res.
  
  Volume: 27 Issue: 6 Pages: 1063-1074
- DOI
  10.1111/pcmr.12287
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-25113715, KAKENHI-PROJECT-25293060, KAKENHI-PROJECT-26670124
[Journal Article] Diacylglycerol kinase gamma regulates antigen-induced mast cell degranulation by mediating Ca2+ influxes2014
- Author(s)
  Sakuma, M., Shirai, Y., Ueyama, T., and Saito, N.
- Journal Title
  
  Biochem. Biophys. Res. Commun,
  
  Volume: 445 Issue: 2 Pages: 340-345
- DOI
  10.1016/j.bbrc.2014.01.197
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-25113715, KAKENHI-PROJECT-25293060, KAKENHI-PROJECT-26670124
[Journal Article] Diacylglycerol kinase  regulates antigen-induced mast cell degranulation by mediating Ca2+ influxes2014
- Author(s)
  Sakuma M, Shirai Y, Ueyama T, Saito N
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 445 Pages: 340-345
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460340
[Journal Article] Both the C1 domain and a basic amino acid cluster at C-terminus are important for neurite and branch induction ability of DGK.2014
- Author(s)
  Takuya Kano, Takeshi Kouzuki, Satoru Mizuno, Shuji Ueda, Minoru Yamanoue, Fumio Sakane, Naoaki Saito and Yasuhito Shirai
- Journal Title
  
  iochem. Biophys. Res. Commun
  
  Volume: 印刷中 Issue: 1 Pages: 89-94
- DOI
  10.1016/j.bbrc.2014.03.113
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-25113715, KAKENHI-PUBLICLY-25116704, KAKENHI-PROJECT-25293060, KAKENHI-PROJECT-26291017, KAKENHI-PROJECT-26670124
[Journal Article] RANTES/CCL5 mediated-biological effects depend on the s 1 yndecan-4/PKC signaling pathway2014
- Author(s)
  Maillard L, Saito N, Hlawaty H, Friand V, Suffee N, Chmilewsky F, Haddad O, Laguillier C, Guyot E, Ueyama T, Oudar O, Sutton A, Charnaux N
- Journal Title
  
  Biology Open
  
  Volume: 3 Pages: 995-1004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460340
[Journal Article] RANTES/CCL5 mediated-biological effects depend on the syndecan-4/PKCa signaling pathway2014
- Author(s)
  Maillard, L., Saito, N., Hlawaty, H., Friand, V., Suffee, N., Chmilewsky, F., Haddad, O., Laguillier, C., Guyot, E., Ueyama, T., Oudar, O., Sutton, A., Charnaux, N.
- Journal Title
  
  Biology Open
  
  Volume: 3 Issue: 10 Pages: 995-1004
- DOI
  10.1242/bio.20148227
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-25113715, KAKENHI-PROJECT-25293060, KAKENHI-PROJECT-26670124
[Journal Article] The role of Pak-interacting exchange factor-β phosphorylation at serines 340 and 583 by PKCγ in dopamine release.2014
- Author(s)
  Shirafuji T, Ueyama T, Yoshino K, Takahashi H, Adachi N, Ago Y, Koda K, Nashida T, Hiramatsu N, Matsuda T, Toda T, Sakai N, Saito N.
- Journal Title
  
  J Neurosci
  
  Volume: 34 Issue: 28 Pages: 9268-9280
- DOI
  10.1523/jneurosci.4278-13.2014
- NAID
  120005619641
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22129006, KAKENHI-PUBLICLY-25113715, KAKENHI-PROJECT-25293060, KAKENHI-PROJECT-25293061, KAKENHI-PROJECT-26253057, KAKENHI-PROJECT-26460340, KAKENHI-PROJECT-26670124
[Journal Article] Increased seizure susceptibility in a mouse with diacylglycerol kinase β 2 deficiency2013
- Author(s)
  Ishisaka, M., Tsuruma, K., Shimazawa, M., Shirai, Y., Saito, N., and Hara, H.
- Journal Title
  
  Neuroscience & Medicine
  
  Volume: 4 Pages: 117-122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293060
[Journal Article] Mutant gammaPKC that causes spinocerebellar ataxia type 14 upregulates Hsp70, which protects cells from the mutant's cytotoxicity.2013
- Author(s)
  Ogawa, K., Seki, T., Onji, T., Adachi, N., Tanaka, S., Hide, I., Saito, N., Sakai, N.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 440 Issue: 1 Pages: 25-30
- DOI
  10.1016/j.bbrc.2013.09.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590321, KAKENHI-PROJECT-24591264, KAKENHI-PROJECT-24659117, KAKENHI-PUBLICLY-25113715, KAKENHI-PROJECT-25293060, KAKENHI-PROJECT-25293061, KAKENHI-PROJECT-25430065
[Journal Article] Increased seizure susceptibility in a mouse with diacylglycerol kinase β 2 deficiency.2013
- Author(s)
  Ishisaka, M., Tsuruma, K., Shimazawa, M., Shirai, Y., Saito, N., and Hara, H.
- Journal Title
  
  Neuroscience & Medicine.
  
  Volume: 4 Pages: 117-122
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25113715
[Journal Article] Both C1B domain and pseudosubstrate region are necessary for saturated fatty acidmembrane; distinct role of intramolecular domains for different translocation2013
- Author(s)
  Nishimoto, T., Kashiwagi, K., Saito, N., and Shirai, Y
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 432 Pages: 384-388
- Data Source
  KAKENHI-PROJECT-23659137
[Journal Article] PKC-ε pseudosubstrate and catalytic activity are necessary for membrane delivery during IgG-mediated phagocytosis.2013
- Author(s)
  Wood, TR., Chow, RY., Hanes, CM., Zhang, X., Kashiwagi, K., Shirai, Y., Trebak, M., Loegering, DJ., Saito, N., and Lennartz, MR.
- Journal Title
  
  J Leukoc Biol
  
  Volume: 94 Issue: 1 Pages: 109-122
- DOI
  10.1189/jlb.1212634
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25113715, KAKENHI-PROJECT-25293060
[Journal Article] Both C1B domain and pseudosubstrate region are necessary for saturated fatty acid membrane;distinct role of intramolecular domains for different2013
- Author(s)
  Takaaki Nishimoto, T., Kashiwagi, K., Saito, N., and Shirai, Y.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 432 Issue: 2 Pages: 384-388
- DOI
  10.1016/j.bbrc.2013.01.048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659137, KAKENHI-PUBLICLY-25113715, KAKENHI-PROJECT-25293060, KAKENHI-PUBLICLY-23113511
[Journal Article] Negative Charges in the Flexible N-Terminal Domain of Rho GDP-Dissociation Inhibitors (RhoGDIs) Regulate the Targeting of the RhoGDI-Rac1 Complex to Membranes2013
- Author(s)
  Ueyama T, Son J, Kobayashi T, Hamada T, Nakamura T, Sakaguchi H, Shirafuji T, Saito N
- Journal Title
  
  J. Immunol.
  
  Volume: 191 Issue: 5 Pages: 2560-2569
- DOI
  10.4049/jimmunol.1300209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23612002, KAKENHI-PUBLICLY-25113715, KAKENHI-PROJECT-25293060
[Journal Article] Mutant γPKC that causes spinocerebellar ataxia type 14 upregulates Hsp70, which protects cells from the mutant's cytotoxicity.2013
- Author(s)
  Ogawa K, Seki T, Onji T, Adachi N, Tanaka S, Hide I, Saito N, Sakai N.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 11;440(1) Pages: 25-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790252
[Journal Article] Protein kinase Cη is targeted to lipid droplets.2013
- Author(s)
  Suzuki Michitaka
- Journal Title
  
  Histochem Cell Biol
  
  Volume: 139 Issue: 4 Pages: 505-511
- DOI
  10.1007/s00418-013-1083-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659094, KAKENHI-PROJECT-24390045, KAKENHI-PUBLICLY-25113715, KAKENHI-PROJECT-25293060, KAKENHI-PUBLICLY-23113711
[Journal Article] Novel PKCα-mediated phosphorylation site(s) on cofilin and their potential role in terminating histamine release2012
- Author(s)
  Sakuma, M., Shirai, Y., Yoshino, K-I., Kuramasu, M., Nakamura, T., Yanagita, T., Mizuno, K., Hide, I., Nakata, Y., Saito, N.
- Journal Title
  
  Mol Biol Cell
  
  Volume: 23(18) Pages: 3707-3721
- Data Source
  KAKENHI-PROJECT-23659137
[Journal Article] Establishment of a Novel Fluorescence-Based Method to Evaluate Chaperone-Mediated Autophagy in a Single Neuron.2012
- Author(s)
  Seki, T., Yoshino, K., Tanaka, S., Dohi, E., Onji, T., Yamamoto, K., Hide, I., Paulson, H.L., Saito, N., Sakai, N
- Journal Title
  
  PLoS ONE
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659137
[Journal Article] MARCKS dephosphorylation is involved in bradykinin-induced neurite outgrowth in neuroblastoma SH-SY5Y cells2012
- Author(s)
  Tanabe A, Shiraishi M, Negishi M, Saito N, Tanabe M, and Sasaki Y
- Journal Title
  
  J Cell Physiol
  
  Volume: 227(2) Pages: 618-629
- Data Source
  KAKENHI-PROJECT-23659137
[Journal Article] Establishment of a Novel Fluorescence-Based Method to Evaluate Chaperone-Mediated Autophagy in a Single Neuron2012
- Author(s)
  Seki, T., Yoshino, K., Tanaka, S., Dohi, E., Onji, T., Yamamoto, K., Hide, I., Paulson, H.L., Saito, N., Sakai, N.
- Journal Title
  
  PLoS ONE
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390070
[Journal Article] Establishment of a Novel Fluorescence-Based Method to Evaluate Chaperone-Mediated Autophagy in a Single Neuron.2012
- Author(s)
  Seki, T., Ken-ich Yoshino, K., Tanaka, S., Dohi, E., Onji, T., Yamamoto, K., Hide, I., Paulson, H.L., Saito, N., Sakai, N
- Journal Title
  
  PLoS ONE
  
  Volume: 7(2)
- Data Source
  KAKENHI-PROJECT-23659137
[Journal Article] MARCKS dephosphorylation is involved in bradykinin-induced neurite outgrowth in neuroblastoma SH-SY5Y cells2012
- Author(s)
  Tanabe A, Shiraishi M, Negishi M, Saito N, Tanabe M, and Sasaki Y.
- Journal Title
  
  J Cell Physiol
  
  Volume: 227(2) Pages: 618-629
- Data Source
  KAKENHI-PROJECT-21390070
[Journal Article] Novel PKCalphamediated phosphorylation site(s) on cofilin and their potential role in2012
- Author(s)
  Sakuma, M., Shirai, Y., Yoshino, K^I., Kuramasu,M., Nakamura, T., Yanagita, T., Mizuno, K.,Hide, I., Nakata, Y., Saito, N.
- Journal Title
  
  Mol Biol. Cell
  
  Volume: 23 Pages: 3707-3721
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659137
[Journal Article] MARCKS dephosphorylation is involved in bradykinin-induced neurite outgrowth in neuroblastoma SH-SY5Y cells.2012
- Author(s)
  Tanabe A, Shiraishi M, Negishi M, Saito N, Tanabe M, and Sasaki Y.
- Journal Title
  
  J Cell Physiol.
  
  Volume: 227 Issue: 2 Pages: 618-629
- DOI
  10.1002/jcp.22763
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659137, KAKENHI-PROJECT-23780298, KAKENHI-PUBLICLY-23113511
[Journal Article] Novel PKC#61537;-mediated phosphorylation site(s) on cofilin and their potential role in terminating histamine release"2012
- Author(s)
  Sakuma, M., Shirai, Y., Yoshino, K^I., Kuramasu, M., Nakamura, T., Yanagita, T., Mizuno, K., Hide, I., Nakata, Y., Saito, N.
- Journal Title
  
  Mol Biol. Cell
  
  Volume: 23 Pages: 3707-3721
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23113511
[Journal Article] Establishment of a Novel Fluorescence-Based Method to Evaluate Chaperone-Mediated Autophagy in a Single Neuron2012
- Author(s)
  Seki, T., Ken-ich Yoshino, K., Tanaka, S., Dohi, E., Onji, T., Yamamoto, K., Hide, I., Paulson, H. L., Saito, N., Sakai, N.
- Journal Title
  
  PLoS ONE
  
  Volume: 7(2)
- Data Source
  KAKENHI-PROJECT-21390070
[Journal Article] c-Abl tyrosine kinase regulates serum-induced nuclear export of diacylglycerol kinaseαby phosphorylation at Tyr2182012
- Author(s)
  Matsubara, T., Ikeda, M., Kiso, Y., Sakuma, M., Yoshino, K-I., Sakane, F., Merida, I., Saito, N. and Shirai, Y.
- Journal Title
  
  J. Biol. Chem
  
  Volume: 287 Pages: 5507-5517
- Data Source
  KAKENHI-PROJECT-21390070
[Journal Article] MARCKS dephosphorylation is involved in bradykinin-induced neurite outgrowth in neuroblastoma SH-SY5Y cells2012
- Author(s)
  Tanabe A, Shiraishi M, Negishi M, Saito N, Tanabe M, Sasaki Y
- Journal Title
  
  J Cell Physiol
  
  Volume: 227 Pages: 618-629
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390070
[Journal Article] c-Abl tyrosine kinase regulates serum-induced nuclear export of diacylglycerol kinase αby phosphorylation at Tyr2182012
- Author(s)
  Matsubara, T., Ikeda, M., Kiso, Y., Sakuma, M., Yoshino, K-I., Sakane, F., Merida, I., Saito, N. and Shirai, Y
- Journal Title
  
  J. Biol. Chem
  
  Volume: 287 Pages: 5507-5517
- Data Source
  KAKENHI-PROJECT-23659137
[Journal Article] c-Abl tyrosine kinase regulates serum-induced nuclear export of diacylglycerol kinase α by phosphorylation at Tyr2182012
- Author(s)
  Matsubara, T., Ikeda, M., Kiso, Y., Sakuma, M., Yoshino, K-I., Sakane, F., Merida, I., Saito, N., Shirai, Y.
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 287 Pages: 5507-5517
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390070
[Journal Article] c-Abl tyros ine kinase regulates serum-induced nuclear export of diacylglycerol kinase α by phosphorylation at Tyr2182012
- Author(s)
  Matsubara T, Ikeda M, Kiso Y, Sakuma M, Yoshino K-I, Sakane F, Merida I, Saito N, Shirai Y
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 287 Pages: 5507-5517
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23113511
[Journal Article] Nuclear Choline Acetyltransferase Activates Transcription of a High-affinity Choline Transporter2011
- Author(s)
  Matsuo, A., Bellier, J-P, Nishimura, M., Yasuhara, O., Saito, N. and Kimura, H
- Journal Title
  
  J. Biol. Chem
  
  Volume: 286 Pages: 5836-5845
- Data Source
  KAKENHI-PROJECT-23659137
[Journal Article] Nuclear Choline Acetyltransferase Activates Transcription of a High-affinity Choline Transporter2011
- Author(s)
  Matsuo, A., Bellier, J-P, Nishimura, M., Yasuhara, O., Saito, N. and Kimura, H.
- Journal Title
  
  J. Biol. Chem
  
  Volume: 286 Pages: 5836-5845
- Data Source
  KAKENHI-PROJECT-21390070
[Journal Article] Streptococcus mutans diacylglycerol kinase homologue : a potential target for anti-caries chemotherapy2011
- Author(s)
  Shibata, Y., Kawada-Matsuo, M., Shirai, Y, Saito, N., Li.D., Yamashita, Y.
- Journal Title
  
  J.Med.Microbiol.
  
  Volume: 60 Pages: 625-630
- NAID
  120004951599
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390070
[Journal Article] Cooperation of p40phox with p47phox for Nox2 activation during FcγR-mediated phagocytosis --Mechanism for acquisition of p40phox PI(3)P binding--2011
- Author(s)
  Ueyama, T., Nakakita, J., Kobayashi, T., Kobayashi, T., Son, J-h., Sakaguchi, H., Leto, T., and Saito, N
- Journal Title
  
  J. Biol. Chem
  
  Volume: 286 Pages: 40693-40705
- Data Source
  KAKENHI-PROJECT-23659137
[Journal Article] Direct binding of RalA to PKCh and its crucial role in morphological change during keratinocytes differentiation2011
- Author(s)
  Shirai Y, Morioka S, Sakuma M, Yoshino K, Otsuji C, Sakai N, Kashiwagi K, Chida K, Shirakawa R, Horiuchi H, Nishigori C, Ueyama T, Saito N
- Journal Title
  
  Mol.Biol.Cell
  
  Volume: 22 Pages: 1340-1352
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23113511
[Journal Article] c-Abl tyrosine kinase regulates serum-induced nuclear export of diacylglycerol kinase α by phosphorylation at Tyr2182011
- Author(s)
  Matsubara, M., Ikeda, M., Kiso, Y., Sakuma, M., Sakane, F., Merida, I, Saito, N., Shirai, Y.
- Journal Title
  
  J.Biol.Chem
  
  Volume: 287 Issue: 8 Pages: 5507-5517
- DOI
  10.1074/jbc.m111.296897
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570139, KAKENHI-PROJECT-23659137, KAKENHI-PUBLICLY-23113511
[Journal Article] Elucidation of the Molecular Mechanism and Exploration of Novel Therapeutics for Spinocerebellar Ataxia Caused by Mutant Protein Kinase Cγ.2011
- Author(s)
  Seki, T., Adachi, N., Abe-Seki, N., Shimahara, T., Takahashi, H., Yamamoto, K., Saito, N. and Sakai, N．
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 116 Pages: 239-247
- NAID
  10029894921
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659137
[Journal Article] Streptococcus mutans diacylglycerol kinase homologue : a potential target for anti-caries chemotherapy2011
- Author(s)
  Shibata, Y., Kawada-Matsuo, M., Shirai, Y., Saito, N., Li. D., and Yamashita, Y.
- Journal Title
  
  J. Med. Microbiol
  
  Volume: 60 Pages: 625-630
- NAID
  120004951599
- Data Source
  KAKENHI-PROJECT-21390070
[Journal Article] Elucidation of the Molecular Mechanism and Exploration of Novel Therapeutics for Spinocerebellar Ataxia Caused by Mutant Protein Kinase Cγ2011
- Author(s)
  Seki, T., Adachi, N., Abe-Seki, N., Shimahara, T., Takahashi, H., Yamamoto, K., Saito, N. and Sakai, N
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 116 Pages: 239-247
- NAID
  10029894921
- Data Source
  KAKENHI-PROJECT-23659137
[Journal Article] Elucidation of the Molecular Mechanism and Exploration of Novel Therapeutics for Spinocerebellar Ataxia Caused by Mutant Protein Kinase Cγ2011
- Author(s)
  Seki, T., Adachi, N., Abe-Seki, N., Shimahara, T., Takahashi, H., Yamamoto, K., Saito, N. and Sakai, N.
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 116 Pages: 239-247
- NAID
  10029894921
- Data Source
  KAKENHI-PROJECT-21390070
[Journal Article] Molecular pathophysiology of neurodegenerative disease caused by PKC mutations.2011
- Author(s)
  Sakai, N., Saito, N. and Seki, T.
- Journal Title
  
  World J. Biological Psychiatry
  
  Volume: 12 Pages: 95-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659137
[Journal Article] Molecular pathophysiology of neurodegenerative disease caused by γPKC mutations2011
- Author(s)
  Sakai, N., Saito, N., Seki, T.
- Journal Title
  
  World J.Biological Psychiatry
  
  Volume: 12 Pages: 95-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390070
[Journal Article] Cooperation of p40phox with p47phox for Nox2 activation during Fc{lower case gamma} R-mediated phagocytosis--Mechanism for acquisition of p40phox PI(3)P binding--2011
- Author(s)
  Ueyama, T., Nakakita, J., Kobayashi, T., Kobayashi, T.,-hyun Son, J-h., Sakaguchi, H., Leto, T., Saito, N.
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 286 Pages: 40693-40705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390070
[Journal Article] Direct binding of RalA to PKCη and its crucial role in morphological change during keratinocytes differentiation2011
- Author(s)
  Shirai, Y., Morioka, S., Sakuma, M., Yoshino, K., Otsuji, C., Sakai, N., Kashiwagi, K., Chida, K., Shirakawa, R., Horiuchi, H., Nishigori, C., Ueyama, T., Saito, N.
- Journal Title
  
  Mol.Biol.Cell
  
  Volume: 22 Pages: 1340-1352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390070
[Journal Article] Nuclear Choline Acetyltransferase Activates Transcription of a High-affinity Choline Transporter2011
- Author(s)
  Matsuo, A., Bellier, J-P, Nishimura, M., Yasuhara, O., Saito, N., Kimura, H.
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 286 Pages: 5836-5845
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390070
[Journal Article] Streptococcus mutans diacylglycerol kinase homologue:a potential target for anti-caries chemotherapy2011
- Author(s)
  Shibata, Y., Kawada-Matsuo, M., Shirai, Y., Saito, N.,Li. D., and Yamashita, Y
- Journal Title
  
  J. Med. Microbiol
  
  Volume: 60 Pages: 625-630
- Data Source
  KAKENHI-PROJECT-23659137
[Journal Article] Direct binding of RalA to PKCh and its crucial role in morphological change during keratinocytes differentiation2011
- Author(s)
  Shirai, Y., Morioka, S., Sakuma, M., Yoshino, K., Otsuji, C., Sakai, N., Kashiwagi, K., Chida, K., Shirakawa, R., Horiuchi, H., Nishigori, C., Ueyama, T., Saito, N.
- Journal Title
  
  Mol. Biol. Cell
  
  Volume: 22 Pages: 1340-1352
- Data Source
  KAKENHI-PROJECT-21390070
[Journal Article] Cooperation of p40phox with p47phox for Nox2 activation during FcgR-mediated phagocytosis--Mechanism for acquisition of p40phox PI(3)P binding--2011
- Author(s)
  Ueyama T, Nakakita J, Nakamura T, Kobayashi T, Kobayashi T, Son J-h, Sakuma M, Sakaguchi H, Leto T, Saito N
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 286 Pages: 40693-40705
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23113511
[Journal Article] Establishment of a novel fluorescence-based method to evaluate chaperone-mediate autophagy in a singlz neuron2011
- Author(s)
  Seki, T., Ki Y., Tanaka, S., Dohi, E., Onji, T., Yamamoto, K., Seki T, Yoshino KI, Tanaka S, Dohi E, Onji T, Yamamoto K, Hide, I., Sakai, N. et al.
- Journal Title
  
  PLoS ONE
  
  Volume: 7 Issue: 2 Pages: e31232-e31232
- DOI
  10.1371/journal.pone.0031232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590281, KAKENHI-PROJECT-21591086, KAKENHI-PROJECT-22390049, KAKENHI-PROJECT-23659137, KAKENHI-PROJECT-23700450, KAKENHI-PROJECT-24590321, KAKENHI-PROJECT-24591264, KAKENHI-PROJECT-24659117, KAKENHI-PUBLICLY-23113511
[Journal Article] Cooperation of p40phox with p47phox for Nox2 activation during Fc{lower case gamma} R-mediated phagocytosis-Mechanism for acquisition of p40phox PI(3) P binding-2011
- Author(s)
  Ueyama, T., Nakakita, J., Kobayashi, T., Kobayashi, T., Son, J-h., Sakaguchi, H., Leto, T., and Saito, N.
- Journal Title
  
  J. Biol. Chem
  
  Volume: 286 Pages: 40693-40705
- Data Source
  KAKENHI-PROJECT-21390070
[Journal Article] Molecular pathophysiology of neurodegenerative disease caused by γPKC mutations2011
- Author(s)
  Sakai, N., Saito, N. and Seki, T
- Journal Title
  
  World J. Biological Psychiatry
  
  Volume: 12(S1) Pages: 95-98
- Data Source
  KAKENHI-PROJECT-23659137
[Journal Article] Direct binding of RalA to PKC and its crucial role in morphological change during keratinocytes differentiation.2011
- Author(s)
  Shirai, Y., Morioka, S., Sakuma, M., Yoshino, K., Otsuji, C., Sakai, N., Kashiwagi, K., Chida, K., Shirakawa, R., Horiuchi, H., Nishigori, C., Ueyama, T., Saito, N.
- Journal Title
  
  Mol. Biol. Cell
  
  Volume: 22 Pages: 1340-1352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659137
[Journal Article] Nuclear Choline Acetyltransferase Activates Transcription of a High-affinity Choline Transporter2011
- Author(s)
  Matsuo, A., Bellier, J-P, Nishimura, M., Yasuhara, O., Saito, N., Kimura, H.
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 286 Pages: 5836-5845
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23113511
[Journal Article] Direct binding of RalA to PKCη and its crucial role in morphological change during keratinocytes differentiation2011
- Author(s)
  Shirai, Y., Morioka, S., Sakuma, M., Yoshino, K., Otsuji, C., Sakai, N., Kashiwagi, K., Chida, K., Shirakawa, R., Horiuchi, H., Nishigori, C., Ueyama, T., Saito, N
- Journal Title
  
  Mol. Biol. Cell
  
  Volume: 22 Pages: 1340-1352
- Data Source
  KAKENHI-PROJECT-23659137
[Journal Article] Streptococcus mutans diacylglycerol kinase homologue:a potential target for anti-caries chemotherapy.2011
- Author(s)
  Shibata, Y., Kawada-Matsuo, M., Shirai, Y., Saito, N., Li. D., and Yamashita, Y.
- Journal Title
  
  J. Med. Microbiol.
  
  Volume: 60 Pages: 625-630
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659137
[Journal Article] Molecular pathophysiology of neurodegenerative disease caused byγPKC mutations2011
- Author(s)
  Sakai, N., Saito, N. and Seki, T.
- Journal Title
  
  World J. Biological Psychiatry
  
  Volume: 12(S1) Pages: 95-98
- Data Source
  KAKENHI-PROJECT-21390070
[Journal Article] Cooperation of p40phox with p47phox for Nox2 activation during Fc{lower case gamma}R-mediated phagocytosis --Mechanism for acquisition of p40phox PI(3)P binding--"2011
- Author(s)
  Ueyama, T., Nakakita, J., Kobayashi, T., Kobayashi, T., -hyun Son, J-h., Sakaguchi, H., Leto, T., and Saito, N
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 286 Pages: 40693-40705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659137
[Journal Article] Nuclear Choline Acetyltransferase Activates Transcription of a High-affinity Choline Transporter.2011
- Author(s)
  Matsuo, A., Bellier, J-P, Nishimura, M., Yasuhara, O., Saito, N. and Kimura, H.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 286 Pages: 5836-5845
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659137
[Journal Article] Potential Antitumor Activity of a Low Molecular Weight Protein Fraction(MLP-Fraction) from Grifola frondosa through Enhancement of Cytokine Production2010
- Author(s)
  Kodama, N., Mizuno, S., Nanba, H. and Saito, N.
- Journal Title
  
  Journal of Medicinal Food
  
  Volume: 13 Pages: 20-30
- Data Source
  KAKENHI-PROJECT-21390070
[Journal Article] A critical role of conventional protein kinase C in morphological changes of rodent mast cells2010
- Author(s)
  Yanase Y., Hide, I., Mihara, S., Shirai, Y., Saito, N., Nakata, Y., Hide, M., and Sakai, N.
- Journal Title
  
  Immunol. Cell. Biol
  
  Volume: 89(1) Pages: 149-59
- Data Source
  KAKENHI-PROJECT-21390070
[Journal Article] Stimulatory effects of the soy phytoestrogen genistein on noradrenalin transporter and serotonin transporter activity2010
- Author(s)
  Toyohira, Y., Ueno, S., Tsutsui, M., Itho, H., Sakai, N., Saito, N., Takahashi, K., and Yanagihara, N.
- Journal Title
  
  Mol. Nutr. Food Res
  
  Volume: 54 Pages: 516-524
- Data Source
  KAKENHI-PROJECT-21390070
[Journal Article] PKC-induced phosphorylation of Orai1 regulates intracellular Ca2+ level via store operated Ca2+ channel2010
- Author(s)
  Kawasaki, T., Ueyama, T., Lange, I., Feske, S. Saito, N.
- Journal Title
  
  J. Biol. Chem
  
  Volume: 285(33) Pages: 25720-30
- Data Source
  KAKENHI-PROJECT-21390070
[Journal Article] Mutant protein kinase C gamma that causes spinocerebellar ataxia type 14(SCA14) is selectively degraded by autophagy2010
- Author(s)
  Yamamoto, K., Seki, T., Adachi, N., Takahashi, T., Tanaka, S., Hide, I., Saito, N., Sakai, N.
- Journal Title
  
  Genes to Cells
  
  Volume: 15 Pages: 425-38
- Data Source
  KAKENHI-PROJECT-21390070
[Journal Article] Essential role of diacylglycerol kinase beta(DGKb) in neurite spine formation, contributing to cognitive function including spatial and long-term memory2010
- Author(s)
  Shirai, Y., Kozuki, T., Kakefuda, K., Moriguchi, S., Oyagi, A., Horie, K., Shimazawa, M., Fukunaga, K., Takeda, J., Saito, N., Hara, H.
- Journal Title
  
  PLoS One
  
  Volume: 5(7)
- Data Source
  KAKENHI-PROJECT-21390070
[Journal Article] Diacylglycerol kinaseβknockout mice exhibit lithium-sensitive behavioral abnormalities2010
- Author(s)
  Kakefuda K., Oyagi A., Ishisaka M., Tsuruma K., Shimazawa M., Yokota K., Shirai Y., Horie K., Saito N., Takeda J. and Hara H.
- Journal Title
  
  PLoS One
  
  Volume: 5(10)
- Data Source
  KAKENHI-PROJECT-21390070
[Journal Article] The effect of trehalose on the properties of mutantγPKC, which causes spinocerebellar ataxia type 14(SCA14), in neuronal cell lines and cultured Purkinje cells2010
- Author(s)
  Seki, T., Abe-Seki, N., Kikawada, T., Takahashi, H., Yamamoto, K., Adachi, N., Tanaka, S., Hide, I., Saito, N., and Sakai, N.
- Journal Title
  
  J. Biol. Chem
  
  Volume: 285 Pages: 33252-33264
- Data Source
  KAKENHI-PROJECT-21390070
[Journal Article] Supression mechanisms of flavonoids on aryl hydrocarbon receptor-mediated signal transduction2010
- Author(s)
  Mukai, R., Shirai, Y., Saito, N., Fukuda, I., Nishiumi, S., Yoshida, K., Ashida, H.
- Journal Title
  
  Arch. Biochem. Biophys
  
  Volume: 501 Pages: 134-141
- Data Source
  KAKENHI-PROJECT-21390070
[Journal Article] Duox maturation factors form cell surface complexes with Duox affecting the specificitv of reactive oxvaen species generation2009
- Author(s)
  Morand S, Ueyama T, Tsujibe S, Saito N, Korzeniowska A, Leto TL
- Journal Title
  
  FASEB Journal 23
  
  Pages: 1205-1218
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20056022
[Journal Article] Kinase activity of the dgk gene product is involved 1 in the virulence of Streptococcus mutans Microbiology2009
- Author(s)
  Shibata, Y., van der Ploeg, JR., Kozuki, T., Shirai, Y., Saito, N., Kawada, M., Takeshita, T., and Yamashita, Y.
- Journal Title
  
  155
  
  Pages: 557-565
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390064
[Journal Article] Mutant γPKC found in spinocerebellar ataxia type 14 induces aggregate-independent maldevelopment of dendrites in primary cultured Purkinje cells2009
- Author(s)
  Seki, T. ; Shimahara ; T., Yamamoto ; K., Abe ; N., Amano, T. ; Adachi ; N., Takahashi, H. ; Kashiwagi, K. ; Saito, N., Sakai, N.
- Journal Title
  
  Neurobiology of Disease 33
  
  Pages: 260-273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390064
[Journal Article] Ca^<2+> oscillation induced by P2Y2 receptor activation and its regulation by a neuron-specific subtype of PKC (βPKC)2008
- Author(s)
  Ashida, N., Ueyama, T., Rikitake, K., Shirai, Y. Eto, M., Kondoh, T., Kohmura, E., and Saito, N.
- Journal Title
  
  Neurosci. Lett 446
  
  Pages: 123-128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390064
[Journal Article] Identification of SF-1/Ad4BP gene expression modulators by large scale gain and loss of function studies2008
- Author(s)
  Sakai, N., Terami, H., Suzuki, S., Haga, M.,Nomoto, K., Tsuchida, N., Morohashi, KI.,Saito, N., Asada, M., Hashimoto, M.,Harada, D., Asahara, H., Ishikawa, T.,Shimada, F., Sakurada, K.
- Journal Title
  
  J. Endocrinol 198
  
  Pages: 489-497
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390064
[Journal Article] Reactive oxygen species derived from NOX1/NADPH oxidase enhance inflammatory pain2008
- Author(s)
  Ibi, M., Matsuno, K., Shiba, D., Katsuyama, M., Iwata, K., Kakehi, T., Nakagawa, T., Sango, K., Shirai, Y., Yokoyama, T., Kaneko, S., Saito N.,and Yabe-Nishimura, C.
- Journal Title
  
  J. Neurosci 28
  
  Pages: 9486-9494
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390064
[Journal Article] Sequential binding of cytosolic phox proteins to phagosomes through regulated adaptor proteins : evaluation using the novel monomeric Kusabira-Green system and live imaqinq of phaaocytosis2008
- Author(s)
  Kusakabe T, Karasawa S, Kawasaki T, Shimizu A, Son J, LetoT L, Miyawaki A, Saito N
- Journal Title
  
  J of Immunology 181
  
  Pages: 629-640
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20056022
[Journal Article] Sequential Binding of Cytosolic Phox Complex to Phagosomes through Regulated Adaptor Proteins : Evaluation Using the Novel Monomeric Kusabira-Green System and Live Imaging of Phagocytosis2008
- Author(s)
  Ueyama, T., Kusakabe, T., Karasawa, S., Kawasaki, T., Shimizu, A., Son J-H, Shirai, Y., Leto, TL., Miyawaki, A., and Saito N.
- Journal Title
  
  J. Immunol 181
  
  Pages: 629-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390064
[Journal Article] Diacylglycerol kinase β accumulates on the perisynaptic site of medium spiny neurons in the striatum2008
- Author(s)
  Hozumi,Y., Fukaya, M., Adachi, N., Saito, N., Otani, K., Kondo, K., Watanabe, M., and Goto, K.
- Journal Title
  
  Eur. J. Neurosci 28
  
  Pages: 2409-2422
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390064
[Journal Article] Enzymological analysis of mutant protein kinase C gamma causing spinocerebellar ataxia type 14 and dysfunction in Ca^<2+> homeostasis2008
- Author(s)
  Adachi N, Kobayashi T, Takahashi H, Kawasaki T, Shirai Y, Ueyama T, Matsuda T, Seki T, Sakai N, Saito N
- Journal Title
  
  J of Biological Chemistry 283
  
  Pages: 19854-19863
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20056022
[Journal Article] Metabotropic glutamate receptor subtype-1 is essential for in vivo growth of melanoma2008
- Author(s)
  Ohtani, Y., Harada, T., Funasaka, Y., Nakao, K., Takahara, C., Abdel-Daim, M., Sakai, N., Saito, N., Nishigori, C. and Aiba, A.
- Journal Title
  
  Oncogene 27
  
  Pages: 7162-7170
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390064
[Journal Article] Regulation of Clathrin Dependent Endocytosis by Diacylglycerol kinaseδ2008
- Author(s)
  Kawasaki, T., Kobayashi, T., Ueyama, T., Shirai, Y. and Saito, N.
- Journal Title
  
  -Importance of Kinase Activity and Binding to AP2α-Biochem. J 409
  
  Pages: 471-479
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390064
[Journal Article] Ca^<2+> oscillation induced by P2Y2 receptor activation and its regulation by a neuron-spacific subtype of PKC (γPKC)2008
- Author(s)
  Ashida N, Ueyama T, Rikitake K, Shirai Y, Eto M, Kondoh T, Kohmura E, Saito N
- Journal Title
  
  Neuroscience Letters 446
  
  Pages: 123-128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20056022
[Journal Article] Immunogold electron microscopic demonstration of distinct submembranous localization of the activated γPKC depending on the stimulation2008
- Author(s)
  Oyasu, M., Fujimiya, M., Kashiwagi, K., Ohmori, S., Imaeda, H. and Saito, N.
- Journal Title
  
  J. Histochem. Cytochem 56
  
  Pages: 253-265
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390064
[Journal Article] Synthesis Conformational Analysis, and Biological Evaluation of 1-Hexyl-indolactam-V10 as a Selective Activator for Novel Protein Kinase C Isozymes2008
- Author(s)
  Yanagita, RC, Nakagawa, Y., Yamanaka, N., Kashiwagi, K., Saito, N. and Irie, K.
- Journal Title
  
  J. Med. Chem 51
  
  Pages: 46-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390064
[Journal Article] Lck-dependent tyrosine phosphorylation of DGK alpha regulates its membrane association in T cells2008
- Author(s)
  Merino, E. Avila-Flores, A., Shirai, Y., Moraga, I., Saito, N. and Merida, I.
- Journal Title
  
  J. Immunol 180
  
  Pages: 5805-5815
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390064
[Journal Article] Minireview : Protein kinase Cε-function in neurons2008
- Author(s)
  Shirai, Y., Adachi, N. and Saito, N.
- Journal Title
  
  FEBS J 275
  
  Pages: 3988-3994
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390064
[Journal Article] Enzymological analysis of mutant protein kinase Cγ causing spinocerebellar ataxia type 14 and its dysfunction in Ca^<2+> homeostasis2008
- Author(s)
  Adachi, N., Kobayashi, T., Takahashi, H., Kawasaki, T., Shirai, Y., Ueyama, T., Matsuda, T., Seki, T., Sakai, N. and Saito N.
- Journal Title
  
  J. Biol. Chem 283
  
  Pages: 19854-19863
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390064
[Journal Article] A novel PIP2 binding of εPKC and its contribution to the neurite induction ability2007
- Author(s)
  Shirai, Y., Murakami, T., Kuramasu, M., Iijima L., and Saito, N.
- Journal Title
  
  J. Neurochem 102
  
  Pages: 1635-1644
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390064
[Journal Article] Aggregate Formation of Mutant Protein Kinase C Gamma Found in Spinocerebellar Ataxia Type 14 Impairs Ubiquitin Proteasome System and Induces Endoplasmic Reticulum Stress Eur2007
- Author(s)
  Seki, T., Takahashi, T., Adachi, N., Shimahara, T., Abe, N., Saito, N. and Sakai N.
- Journal Title
  
  J. Neurosci 26
  
  Pages: 3126-3140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390064
[Journal Article] Design and synthesis of 8-octyl-benzolactam-V9, the selective activator for PKCε and η.2006
- Author(s)
  Y.Nakagawa, K.Irie, R.C.Yanagita, H.Ohigashi, K.-i.Tsuda, K.Kashiwagi, N.Saito
- Journal Title
  
  J. Med. Chem. 49 (9)
  
  Pages: 2681-2688
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15208012
[Journal Article] Rat choline acetyltransferase of the peripheral type differs from that of the common type in intracellular translocation.2005
- Author(s)
  Matsuo A., Belliera JP., Hisano T., Aimi Y., Yasuhara O., Tooyama I., Saito N., Kimura H.
- Journal Title
  
  Neurochemistry International 46・5
  
  Pages: 423-433
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15500257
[Journal Article] Phosphorylation of PKC activation loop plays an important role in receptor-mediated translocation of PKC.2005
- Author(s)
  Seki, T., Matsubayashi, H., Amano, T., Shirai, Y., Saito, N., Sakai, N.
- Journal Title
  
  Genes to Cells 10・3
  
  Pages: 225-239
- Data Source
  KAKENHI-PROJECT-15500257
[Journal Article] Effects of different anti-tau antibodies on tau fibrillogenesis : RTA-1 and RTA-2 counteract tau aggregation.2005
- Author(s)
  Taniguchi, T., Sumida, M., Hiraoka, S., Tomoo, K., Kakehi, T., Minoura, K., Sugiyama, S., Inaka, K., Ishida, T., Saito, N., Tanaka, C.
- Journal Title
  
  FEBS Letters 579
  
  Pages: 1399-1404
- Data Source
  KAKENHI-PROJECT-16659065
[Journal Article] Rat choline acetyltransferase of the peripheral type differs from that of the common type in intracellular translocation.2005
- Author(s)
  Matsuo A., Belliera JP., Hisano T., Aimi Y., Yasuhara O., Tooyama I., Saito N., Kimura H.
- Journal Title
  
  Neurochem Int. 46
  
  Pages: 423-433
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15500257
[Journal Article] Effects of different anti-tau antibodies on tau fibrillogenesis : RTA-1 and RTA-2 counteract tau aggregation2005
- Author(s)
  Taniguchi, T., Sumida, M., Hiraoka, S., Tomoo, K., Kakehi, T., Minoura, K., Sugiyama, S., Inaka, K., Ishida, T., Saito.N., Tanaka C.
- Journal Title
  
  FEBS Letter 579・6
  
  Pages: 1399-1404
- Data Source
  KAKENHI-PROJECT-15500257
[Journal Article] Ceramide-induced apoptosis by translocation, phosphorylation and activation of protein kinase C δ in the Golgi complex2004
- Author(s)
  Kajimoto T, Shirai Y, Sakai N, Yamamoto T, Matsuzaki H, Kikkawa U, Saito N
- Journal Title
  
  J.Biol.Chem 279
  
  Pages: 12668-12676
- Data Source
  KAKENHI-PROJECT-15570115
[Journal Article] Down-regulation of Melanogenesis by Phospholipase D2 through Ubiquitin Proteasome-mediated Degradation of Tyrosinase.2004
- Author(s)
  Kageyama, A., Oka, M., Okada, T., Nakamura, S., Ueyama, T., Saito, N., Hearing, VJ, Ichihashi, M., Nishigori, C.
- Journal Title
  
  Journal of Biological Chemistry 279・26
  
  Pages: 27774-277780
- Data Source
  KAKENHI-PROJECT-15500257
[Journal Article] Phospholipase A_2 products retain a neuron specific γ isoform of PKC on the plasma membrane through the C1 domain- a molecular mechanism for sustained enzyme activity2004
- Author(s)
  Yagi K, Shirai Y, Hirai M, Sakai N, Saito N
- Journal Title
  
  Neurochem Inter 45
  
  Pages: 39-47
- Data Source
  KAKENHI-PROJECT-15570115
[Journal Article] Activation and translocation of PKCδ is necessary for VEGF-induced ERK activation through KDR in HEK293T cells2004
- Author(s)
  Kuriyama M, Taniguchi T, Shirai Y, Sasaki A, Yoshimura A, Saito N
- Journal Title
  
  Biochem.Biophys.Res.Comm. 325
  
  Pages: 843-851
- Data Source
  KAKENHI-PROJECT-15570115
[Journal Article] Superoxide (O2-) production at phagosomal cup/phagosome through betaI PKC during FcγR-mediated phagocytosis in microglia.2004
- Author(s)
  Ueyama, T,.Lennartz, M.R., Noda, Y., Kobayashi, T., Shirai, Y., Rikitake, K., Hayashi, S., Sakai, N., Seguchi, H., Sawada, M., Sumimoto, H., Saito.N.
- Journal Title
  
  Journal of Immunology 173・7
  
  Pages: 4582-4589
- Data Source
  KAKENHI-PROJECT-15500257
[Journal Article] Activation and translocation of PKCdelta is necessary for VEGF-induced ERK activation through KDR in HEK293T cells.2004
- Author(s)
  Kuriyama, M., Taniguchi, T., Shirai, Y., Sasaki, A., Yoshimura, A., Saito, N.
- Journal Title
  
  Biochem Biophys Res Commun 325
  
  Pages: 843-851
- Data Source
  KAKENHI-PROJECT-16659065
[Journal Article] Synthesis and phorbol ester binding of the cysteine-rich domains of diacylglycerol kinase (DGK) isozymes; DGKγ and DGKβ are new targets of tumor-promoting phorbol esters.2003
- Author(s)
  M.Shindo, K.Irie, A.Masuda, H.Ohigashi, Y.Shirai, K.Miyasaka, N.Saito
- Journal Title
  
  J. Biol. Chem. 278 (20)
  
  Pages: 18448-18454
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15208012
[Journal Article] A Simple Analog of Tumor-promoting Aplysiatoxin Is an Antineoplastic Agent rather than a Tumor Promoter : Development of a Synthetically Accessible PKC Activator with Bryostatin-like Activity
- Author(s)
  Yu Nakagawa, Y. Yanagita, RC, Hamada, N. Murakami, A. Takahashi, H. Saito, N. Nagai, H. and Irie, K.
- Journal Title
  
  J Am. Chem. Soc (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390064
[Journal Article] Increased seizure susceptibility in a mouse with diacylglycerol kinase β2 deficiency
- Author(s)
  Ishisaka, M., Tsuruma, K., Shimazawa, M., Shirai, Y.,Saito, N., and Hara, H
- Journal Title
  
  Neuroscience & Medicine
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] Cysteine String Protein alpha (CSPa)Ser34特異的リン酸化抗体の作製と機能解析2019
- Author(s)
  白藤俊彦, 上山健彦, 足立直子, 齋藤尚亮
- Organizer
  第60回日本組織細胞化学会総会
- Data Source
  KAKENHI-PROJECT-18K06700
[Presentation] The molecular mechanism of hearing loss caused by a novel DIA1 mutant (R1204X)2017
- Author(s)
  Yuzuru Ninoyu, Shin-ichiro Kitajiri, Takushi Miyoshi, Dean Thumkeo, Hirofumi Sakaguchi, Naoki Watanabe, Shin-ichi Usami, Naoaki Saito, Takehiko Ueyama
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎新聞文化ホール（長崎県・長崎市）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-26460340
[Presentation] Protein kinase C and its involvement in neuronal diseases2016
- Author(s)
  Naoaki Saito
- Organizer
  Neuroscience Network in Kobe シンポジウム
- Place of Presentation
  神戸大学（兵庫県・神戸市）
- Year and Date
  2016-02-19
- Invited
- Data Source
  KAKENHI-PROJECT-25293060
[Presentation] Protein kinase C and its involvement in neuronal diseases2016
- Author(s)
  Naoaki Saito
- Organizer
  Neuroscience Network in Kobe シンポジウム
- Place of Presentation
  神戸大学（兵庫県・神戸市）
- Year and Date
  2016-02-19
- Invited
- Data Source
  KAKENHI-PROJECT-26670124
[Presentation] 脊髄小脳変性症14型におけるPKCのアミロイド様構造体の形成と疾患への関与2015
- Author(s)
  足立直子、高橋英之、白藤俊彦、上山健彦、Michele, Vendruscolo., 入江一浩、平井宏和、酒井規雄、齋藤尚亮
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸国際会議場（兵庫県・神戸市）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-25293060
[Presentation] 脊髄小脳変性症14型におけるPKCのアミロイド様構造体の形成と疾患への関与2015
- Author(s)
  足立直子、高橋英之、白藤俊彦、上山健彦、Michele, Vendruscolo., 入江一浩、平井宏和、酒井規雄、齋藤尚亮
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸国際会議場（兵庫県・神戸市）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-26670124
[Presentation] Cde-42 is required for maintenance of stereocilia and apical junctional complexes in cochlear hair cells2014
- Author(s)
  Ueyama, T. and Saito, N.
- Organizer
  Joint Workshop between University Catholic Louvain and Kobe University
- Place of Presentation
  Brussels, Belgium
- Data Source
  KAKENHI-PROJECT-25293060
[Presentation] 内耳有毛細胞特異的Cdc42ノックアウトマウスは聴毛及び頂側細胞間接着時のアクチン代謝障害により緩徐進行性の高度難聴を呈する2014
- Author(s)
  中村　高志、上山　健彦、坂口　博史、後藤　明弘、森岡　繁文、米村　重信、久　郁男、松田　道行、饗庭　篤、齋藤　尚亮
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター、仙台
- Data Source
  KAKENHI-PUBLICLY-25113715
[Presentation] A protein kinase Cgamma knockout mice as a Parkinsonian model: Involvement of Pak -Interacting Exchange Factorbeta2014
- Author(s)
  齋藤尚亮
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25293060
[Presentation] A protein kinase Cgamma knockout mice as a Parkinsonian model: Involvement of Pak -Interacting Exchange Factorbeta.2014
- Author(s)
  齋藤尚亮
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター、仙台
- Data Source
  KAKENHI-PUBLICLY-25113715
[Presentation] Protein kinase C and its involvement in neurodegenerative disease.2014
- Author(s)
  Naoaki Saito
- Organizer
  Symposium on Membrane Biology
- Place of Presentation
  Seattle, WA, USA
- Invited
- Data Source
  KAKENHI-PUBLICLY-25113715
[Presentation] Cde-42 is required for maintenance of stereocilia and apical junctional complexes in cochlear hair cells.2014
- Author(s)
  Ueyama, T. and Saito, N
- Organizer
  Joint Workshop between University Catholic Louvain and Kobe University
- Place of Presentation
  Brussels, Belgium
- Data Source
  KAKENHI-PUBLICLY-25113715
[Presentation] Protein kinase C and its involvement in neurodegenerative disease2014
- Author(s)
  Naoaki Saito
- Organizer
  Symposium on Membrane Biology
- Place of Presentation
  Seattle WA, USA
- Invited
- Data Source
  KAKENHI-PROJECT-25293060
[Presentation] Both C1 domain and basic amino acid cluster at C-terminus are important for branching and neurite induction of DGKbeta2013
- Author(s)
  Shirai,Y., Takuya,K., Kouzuki,T., Ueda,S., Yamanoue,M., Sakane,F. and Saito,N
- Organizer
  Neuro 2013
- Place of Presentation
  京都国際会館、京都
- Data Source
  KAKENHI-PUBLICLY-25113715
[Presentation] Duox の活性酸素産生機構2013
- Author(s)
  佐久間恵、上山健彦、ヒン田猛、齋藤尚亮
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡(口頭発表・日本語)
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] Both C1 domain and basic amino acid cluster at C-terminus are important for branching and neurite induction of DGK2013
- Author(s)
  Shirai,Y., Takuya,K., Kouzuki,T., Ueda,S., Yamanoue,M., Sakane,F. and Saito,N.
- Organizer
  Neuro 2013
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25293060
[Presentation] Duoxの活性酸素産生機構2013
- Author(s)
  佐久間　恵、上山　健彦、濵田　猛、齋藤　尚亮
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Year and Date
  2013-03-21
- Data Source
  KAKENHI-PUBLICLY-23113511
[Presentation] 黒質線条体系におけるPKCγの基質の解析：β2PIXリン酸化のドパミン遊離への役割2013
- Author(s)
  白藤俊彦、上山健彦、吉野健一、足立直子、高橋英之、香田健、平松直樹、吾郷由希夫、松田敏夫、酒井　規雄、齋藤　尚亮
- Organizer
  第124回日本薬理学会近畿部会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25293060
[Presentation] 黒質線条体系における PKCγの基質の解析:ドパミン遊離におけるβPIX リン酸化の役割2013
- Author(s)
  白藤俊彦、上山健彦、吉野健一、足立直子、高橋英之、吾郷由希夫、松田敏夫、齋藤尚亮
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡(口頭発表・日本語)
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] Duoxの活性酸素産生機構2013
- Author(s)
  佐久間　恵、上山　健彦、濵田　猛、齋藤　尚亮
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] 中枢神経損傷とRho family GTPases (CNS injury and Rho family GTPases)2012
- Author(s)
  上山健彦、齋藤尚亮
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都(口頭発表、英語)
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] 創薬ターゲットとしてのジアシルグリセロールキナーゼ2012
- Author(s)
  白井康仁、齋藤尚亮
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  (京都府)国立京都国際会館(口頭発表、日本語)
- Year and Date
  2012-03-15
- Data Source
  KAKENHI-PROJECT-21390070
[Presentation] 無血清時における核内 DGKalpha の生理機能2012
- Author(s)
  木曽裕子、白井康仁、佐久間恵、池田もも、齋藤尚亮
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都(ポスター発表、日本語)
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] 黒質線条体系における PKCγの基質の解析2012
- Author(s)
  白藤俊彦、吉野健一、足立直子、高橋英之、香田健、梨子田哲明、吾郷由希夫、松田敏夫、齋藤尚亮
- Organizer
  第121回日本薬理学会近畿部会
- Place of Presentation
  徳島(口頭発表・日本語)
- Year and Date
  2012-06-29
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] Involvment of PKCgamma in neurodegenerative disease2012
- Author(s)
  Saito, N., Takahashi, H., Shirafuji, T., Adachi, N., Danno, S., Ueyama, T., Seki, T. and Sakai,N
- Organizer
  14th International congress of histochemistry and cytochemistry
- Place of Presentation
  京都(ポスター・英語)
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] DGKbeta による神経突起伸張機構の解析2012
- Author(s)
  加野拓也、上田修司、山之上稔、齋藤尚亮、白井康仁
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡(ポスター発表・日本語)
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] Involvment of PKCgamma in neurodegenerative disease2012
- Author(s)
  Saito, N., Takahashi, H., Shirafuji, T., Adachi, N., Danno, S., Ueyama, T.,
- Organizer
  14th International congress of histochemistry and cytochemistry
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] ジアシルグリセロールキナーゼのヒスタミン分泌制御における役割2012
- Author(s)
  佐久間恵、白井康仁、上山健彦、齋藤尚亮
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都(ポスター発表、日本語)
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] Role of PKCα-mediated cofilin phosphorylation in the degranulation from RBL-2H3 mast cells2012
- Author(s)
  Sakuma, M., Shirai, Y., Yoshino, K., Kuramasu, M., Nakamura, T., Mizuno, K., Hide,I., Nakata,Y.and Saito,N
- Organizer
  22th IUBMB & 37th FEBS
- Place of Presentation
  スペイン(ポスター発表・英語)
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] Involvment of PKCgamma in neurodegenerative disease2012
- Author(s)
  Saito, N., Takahashi, H., Shirafuji, T., Adachi, N., Danno, S., Ueyama, T.,
- Organizer
  14th International congress of histochemistry and cytochemistry
- Place of Presentation
  Kyoto
- Year and Date
  2012-08-26
- Data Source
  KAKENHI-PUBLICLY-23113511
[Presentation] 細胞内シグナル分子の可視化と細胞機能2012
- Author(s)
  齋藤尚亮
- Organizer
  第89回日本生理学大会
- Place of Presentation
  松本(招待講演・日本語)
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] Glial functions of Rho-family small GTPases during cerebellar development and after CNS injury2012
- Author(s)
  Ueyama,T., Kondoh T., Kohta M., Kohmura,E., Hayashibe,M., Nakamura,T., Sakahara,M., Kassai,H., Nakao,K., Aiba,A. and Saito,N.
- Organizer
  14th International congress of histochemistry and cytochemistry
- Place of Presentation
  京都(ポスター・英語)
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] 創薬ターゲットとしてのジアシルグリセロールキナーゼ2012
- Author(s)
  白井康仁、齋藤尚亮
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都(口頭発表、英語)
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] 細胞内シグナル分子の可視化と細胞機能2012
- Author(s)
  齋藤尚亮
- Organizer
  第89回日本生理学大会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PUBLICLY-23113511
[Presentation] 中枢神経損傷とRho family GTPases2012
- Author(s)
  上山健彦、齋藤尚亮
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  (京都府)国立京都国際会館
- Year and Date
  2012-03-15
- Data Source
  KAKENHI-PROJECT-21390070
[Presentation] 細胞内シグナルの可視化と細胞機能2012
- Author(s)
  齋藤尚亮
- Organizer
  第89日本生理学会大会
- Place of Presentation
  (長野県)松本文化会館
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-21390070
[Presentation] 細胞内シグナル分子の可視化と細胞機能2012
- Author(s)
  齋藤尚亮
- Organizer
  第89回日本生理学大会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-21390070
[Presentation] 異なるチロシンリン酸化によるジアシルグリセロールキナーゼ alpha の局在調節機構2011
- Author(s)
  白井康仁、池田もも、佐久間恵、木曽裕子、齋藤尚亮
- Organizer
  第119回日本薬理学会近畿部会
- Place of Presentation
  名古屋(口頭発表・日本語)
- Year and Date
  2011-07-08
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] Novel phosphorylation site(s) of cofilin by PKCα and its negative role in the degranulation from RBL-2H3 mast cells2011
- Author(s)
  Sakuma,M., Shirai,Y., Yoshino K., Kuramasu,M., Nakamura,T., Mizuno,K., Hide,I., Nakata,Y. and Saito,N
- Organizer
  he American society for cell biology
- Place of Presentation
  デンバー(ポスター発表・英語)
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] Novel phosphorylation site(s) of cofilin by PKCalpha and its negative role in the degranulation from RBL-2H3 mast cells.2011
- Author(s)
  Sakuma,M., Shirai,Y., Yoshino K., Kuramasu, M., Nakamura,T., Mizuno,K., Hide,I., Nakata,Y. and Saito,N.
- Organizer
  The American society for cell biology.
- Place of Presentation
  Denver, USA
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] Nuclear choline acetyltransferase activates transcription of a high-affinity choline transporter2011
- Author(s)
  Matsuo,A., J.P.Bellier., Nishimura,M., Yasuhara,O., Saito,N. and Kimura,H
- Organizer
  8th IBRO worrd congress of neuroscience
- Place of Presentation
  Italy(ポスター発表・英語)
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] Novel phosphorylation site(s) of cofilin by PKCα and its negative role in the degranulation from RBL-2H3 mast cells2011
- Author(s)
  Sakuma, M., Shirai, Y., Yoshino K., Kuramasu, M., Nakamura, T., Mizuno, K., Hide, I., Nakata, Y., Saito, N.
- Organizer
  The American society for cell biology
- Place of Presentation
  デンバー、米国
- Data Source
  KAKENHI-PROJECT-21390070
[Presentation] Novel phosphorylation site(s) of cofilin by PKCalpha contributes to proper termination of histamine release2011
- Author(s)
  佐久間恵、白井康仁、吉野健一、倉増真帆、中村朋文、水野健作、秀和泉、仲田義啓、齋藤尚亮
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都(口頭発表、日本語)
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] プロテインキナーゼCのトランスロケーションと酵素活性に対するプロポフェノールの効果2011
- Author(s)
  宮原岳史、関貴弘、秀和泉、田中茂、齋藤尚亮、入船正浩、酒井規雄
- Organizer
  第120回日本薬理学会近畿部会
- Place of Presentation
  京都(ポスター発表・日本語)
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] 部位特異的KOマウスを用いた低分子量Gタンパク質の組織学的機能解析2011
- Author(s)
  上山健彦、齋藤尚亮
- Organizer
  日本組織細胞化学会年会
- Place of Presentation
  金沢(招待講演、日本語)
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] PKCgノックアウトは黒質線条体ドパミン神経系の異常をもたらす2010
- Author(s)
  白藤俊彦、足立直子、高橋英之、香田健、梨子田哲明、吾郷由希夫、松田敏夫、齋藤尚亮
- Organizer
  第118回日本薬理学会近畿部会
- Place of Presentation
  大阪
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-21390070
[Presentation] Visualization of PKC targeting and its involvement in the pathogenesis of spinocerebellar ataxia2010
- Author(s)
  Saito, N.
- Organizer
  第51回日本組織細胞化学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21390070
[Presentation] PKC targeting and its involvement in the pathogenesis of spinocerebellar ataxia2010
- Author(s)
  Saito, N.
- Organizer
  14^<th> International congress of Endocrinology
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-21390070
[Presentation] Molecular pathophysiology of spinocerebellar ataxia type14(SCA14), a hereditary neurodegenerative disease caused byγPKC mutations2009
- Author(s)
  Sakai, N., Seki, T., Adachi, N., Takahashi, H. and Saito, N.
- Organizer
  Japan-Taiwan joint symposium on Cell Sygnaling and Gene Regulation
- Place of Presentation
  Kobe, Japan
- Data Source
  KAKENHI-PROJECT-21390070
[Presentation] 気分障害と神経特異的ジアシルグリセロール2009
- Author(s)
  白井康仁、齋藤尚亮
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390064
[Presentation] マウス初代培養表皮細胞におけるRac3のRac1代償機能2009
- Author(s)
  清水彩、上山健彦、坂原瑞穂、饗場篤、齋藤尚亮
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-19390064
[Presentation] 神経特異的ジアシルグリセロールキナーゼDGKβの機能解析2009
- Author(s)
  上月健、白井康仁、掛札賢一、大八木篤、堀江恭二、嶋澤雅光、福永浩司、竹田潤二、齋藤尚亮、原英彰
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390064
[Presentation] 神経特異的ジアシルグリセロールキナーゼDGKβの機能解析2008
- Author(s)
  白井康仁、上月健、掛札賢一、大八木篤、堀江恭二、嶋澤雅光、竹田潤二、齋藤尚亮、原英彰
- Organizer
  BMB2008(第31回日本分子生物学会年会・第81回日本生化学大会合同大会)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19390064
[Presentation] Sequential binding of cytosolic phox complex to phagosomes through regulated adaptor proteins : evaluation using the novel monomeric Kusabira-Green (mKG) system and live imaging of phagocytosis2008
- Author(s)
  Ueyama T, Kusakabe T, Karasawa S, Kawasaki T, Shimizu A, Son J, Leto TL, Miyawaki A, Saito N
- Organizer
  Gordon Research Conferences (NADPH oxidase)
- Place of Presentation
  Colby-Sawyer College, Laconia, NH, USA
- Data Source
  KAKENHI-PROJECT-20056022
[Presentation] Sequential binding of cytosolic phox complex to phagosomes through regulated adaptor proteins : evaluation using the novel monomeric Kusabira-Green(mKG)system and liveimaging of phagocytosis2008
- Author(s)
  Ueyama,T., Kusakabe,T., Karasawa,S., Kawasaki,T., Shimizu,A., Son, Jeong-hyun., Leto,L.Thomas., Miyawaki,A., Saito,N.
- Organizer
  Gordon Research Conference
- Place of Presentation
  ボストン
- Data Source
  KAKENHI-PROJECT-19390064
[Presentation] Recessive embryonic lethality in mutant mice carrying a gene trap in intron 3 of RKIP-1 gene(92)2008
- Author(s)
  Uo,M., Ohmori,S., Nakao,K., Saito,N.
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390064
[Presentation] Differential regulation of dual oxidase 1 by dual activator 1 splicing variants2008
- Author(s)
  Tsujibe,S., Ueyama,T., Shirai,Y., Leto L. Thomas., Saito,N.
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390064
[Presentation] Live imaging of PKC signaling and its implication in neuronal disease2007
- Author(s)
  Naoaki Saito
- Organizer
  14^<th> Congress of Ca2+ binding proteins & Ca2+ function in health & disease
- Place of Presentation
  La Palma Spain
- Data Source
  KAKENHI-PROJECT-19390064
[Presentation] DG-PKCシグナル系の可視化とその異常による疾患2007
- Author(s)
  斎藤尚亮, 他
- Organizer
  第49回日本脂質生化学会
- Place of Presentation
  北海道大学
- Year and Date
  2007-06-06
- Data Source
  KAKENHI-PROJECT-19390064
[Presentation] 緑色蛍光蛋白(GFP)発現バイオ試料の半導体レーザ超短パルス光源による2光子イメージング2007
- Author(s)
  佐藤綾耶、高島啓次郎、郭亨長、牟禮勝仁、横山弘之、坪川宏、齋藤尚亮
- Organizer
  第68回日本応用物理学会学術講演会
- Place of Presentation
  北海道
- Data Source
  KAKENHI-PROJECT-19390064
[Presentation] Clarification of regulatory mechanism of Orail(SOCs)by PKC2007
- Author(s)
  Kawasaki,T., Ueyama,T., Shirai,Y., Saito, N.
- Organizer
  14^<th> Congress of Ca2+ binding proteins & Ca2+ function in health & disease
- Place of Presentation
  La Palma Spain
- Data Source
  KAKENHI-PROJECT-19390064
[Presentation] 脊髄小脳失調症14型における変異PKCγのC1Aとキナーゼドメインを介した分子間相互作用・凝集体形成傾向の重要性2007
- Author(s)
  高橋英之、足立直子、杉本卓弥、中北順也、関貴弘、入江一浩、酒井規雄、齋藤尚亮
- Organizer
  第112回日本薬理学会近畿部会
- Place of Presentation
  千里ライフサイエンスセンター(大阪)
- Year and Date
  2007-11-16
- Data Source
  KAKENHI-PROJECT-19390064
[Presentation] 核内脂質シグナル及び核移行蛋白質の可視化システムを用いた細胞周期機構の解明-DGK の核-細胞質間移行機構と核内における機能に着目して-2007
- Author(s)
  白井康仁、松原岳大、齋藤尚亮
- Organizer
  第49回日本脂質生化学会
- Place of Presentation
  北海道
- Data Source
  KAKENHI-PROJECT-19390064
[Presentation] Enzymological properties of PKCγ mutants found in spinocerebellar ataxia 14(SCA14) and its involvement in neuronal death2007
- Author(s)
  Saito,N., Adachi,N., Takahashi,H., Kobayashi,T., Seki,T. Sakai,N.
- Organizer
  International symposium on cell signaling and gene regulation
- Place of Presentation
  Taiwan
- Data Source
  KAKENHI-PROJECT-19390064
[Presentation] D核内脂質シグナル及び核移行蛋白質の可視化システムを用いた細胞周期機構の解明-DGKの核-細胞質間移行機構と核内における機能に着目して2007
- Author(s)
  白井康仁、松原岳大、齋藤尚亮
- Organizer
  第49回日本脂質生化学会
- Place of Presentation
  北海道
- Data Source
  KAKENHI-PROJECT-19390064
[Presentation] ヒトケラチノサイトにおけるTNF-αによるNGF 分泌促進作用とそのシグナル2007
- Author(s)
  伝達機能, 高岡幸二、白井康仁、齋藤尚亮
- Organizer
  第111回日本薬理学会近畿部会
- Place of Presentation
  名古屋
- Year and Date
  2007-06-15
- Data Source
  KAKENHI-PROJECT-19390064
[Presentation] Live imaging of PKC signaling and its implication in neuronal disease2007
- Author(s)
  Naoaki Saito, et al.
- Organizer
  14^<th> Congress of Ca^<2+> binding proteins & Ca^<2+> function in health & disease
- Place of Presentation
  La Palma, Spain
- Year and Date
  2007-10-18
- Data Source
  KAKENHI-PROJECT-19390064
[Presentation] Enzymological properties of PKCγ mutants found in spinocerebellar ataxia 14(SCA14) and its involvement in neuronal death2007
- Author(s)
  Saito, N., et al.
- Organizer
  International symposium on cell signaling and gene regulation
- Place of Presentation
  Tainan, Taiwan
- Year and Date
  2007-11-18
- Data Source
  KAKENHI-PROJECT-19390064
[Presentation] DG-PKCシグナル系の可視化とその異常による疾患2007
- Author(s)
  齋藤尚亮, 他
- Organizer
  第49回日本脂質生化学会
- Place of Presentation
  北海道大学
- Year and Date
  2007-06-06
- Data Source
  KAKENHI-PROJECT-18053016
[Presentation] c-Ab1, a tyrosine kinase involved in chronic myeloid leukemia, regulates nucleo-cytoplasmic shuttling of DGKαand cell cycle2007
- Author(s)
  Shirai,Y., Matsubara,T., Saito, N.
- Organizer
  FASEB Summer Research Conferences
- Place of Presentation
  Indian Wells CA
- Data Source
  KAKENHI-PROJECT-19390064
[Presentation] Live Imaging of PKC signaling and its implication in meuronal disease.2007
- Author(s)
  Naoaki Saito, et. al.
- Organizer
  14^th Congress of Ca^2+ bingding proteins & Ca^2+ function in health & disease.
- Place of Presentation
  LA palma, Spain
- Year and Date
  2007-10-18
- Data Source
  KAKENHI-PROJECT-18053016
[Presentation] Dysfunction of intracellular Ca2+ regulation in SCA142007
- Author(s)
  Adachi,N., Kobayashi,T., Seki,T., Sakai,N., Saito, N.
- Organizer
  14^<th> Congress of Ca2+ binding proteins & Ca2+ function in health & disease
- Place of Presentation
  La Palma Spain
- Data Source
  KAKENHI-PROJECT-19390064
[Presentation] A regulated adaptor function of p40phox : Intramolecular interaction (PX-PB1 domain)within p40phox2007
- Author(s)
  Ueyama,T., Tatsuno,T., Kawasaki,T., Thomas L.Leto., Saito, N.
- Organizer
  Gordon Research Conference
- Place of Presentation
  ロードアイランド
- Data Source
  KAKENHI-PROJECT-19390064
[Presentation] Enzymological properites of PKCγ mutants found in spinocerebellar ataxia 14(SCA14) and its involvement in neuronal death.2007
- Author(s)
  Saito, N., et. al.
- Organizer
  lnternational symopsium on cell signaling and gene regulation.
- Place of Presentation
  Tainan, Taiwan
- Year and Date
  2007-11-18
- Data Source
  KAKENHI-PROJECT-18053016
[Presentation] DG-PKCシグナル系の可視化とその異常による疾患2007
- Author(s)
  齋藤尚亮、白井康仁、松原岳大、足立直子、高橋英之、酒井規雄
- Organizer
  第49回日本脂質生化学会
- Place of Presentation
  北海道
- Data Source
  KAKENHI-PROJECT-19390064
[Presentation] P2Y受容体を介するγPKCのオシレーション機構の解明2006
- Author(s)
  芦田典明、上山健彦、力武恭子、白井康仁、衛藤三佳、近藤威、甲村英二、齋藤尚亮
- Organizer
  第113回日本薬理学会近畿部会
- Place of Presentation
  岡山
- Year and Date
  2006-06-20
- Data Source
  KAKENHI-PROJECT-19390064
[Presentation] RalAはηPKCによるケラチノサイトの扁平化に必須である。2006
- Author(s)
  白井康仁、盛岡祥子、大辻千裕、吉野健一、酒井規雄、上山健彦、齋藤尚亮
- Organizer
  第113回日本薬理学会近畿部会
- Place of Presentation
  岡山
- Year and Date
  2006-06-20
- Data Source
  KAKENHI-PROJECT-19390064
[Presentation] ・Maintenance of stereocillia and apical junctional complexes by Cdc42 in cochlear hair cells.
- Author(s)
  Ueyama, T., Sakaguchi,H., Nakamura, T., Goto, A., Morioka, S., Fritzsch, B., Hisa, Y., Matsuda, M., Aiba, A. and Saito, N.
- Organizer
  Society for Neuroscience
- Place of Presentation
  Washington DC, USA
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-26670124
[Presentation] Cdc42 is required for maintenance of stereocilia and apical junctional complexes in cochlear hair cells.
- Author(s)
  Ueyama, T., Sakaguchi, H., Goto, A., Hisa, Y., Matsuda, M., Aiba, A. and Saito, N.
- Organizer
  The 37th Naito Conference
- Place of Presentation
  北海道ニセコ
- Year and Date
  2014-07-15 – 2014-07-18
- Data Source
  KAKENHI-PUBLICLY-25113715
[Presentation] Cdc42 is required for maintenance of stereocilia and apical junctional complexes in cochlear hair cells.
- Author(s)
  Ueyama, T., Sakaguchi, H., Goto, A., Hisa, Y., Matsuda, M., Aiba, A. and Saito, N.
- Organizer
  The 37th Naito Conference,
- Place of Presentation
  北海道ニセコ
- Year and Date
  2014-07-15 – 2014-07-18
- Data Source
  KAKENHI-PROJECT-26670124
[Presentation] 細胞内シグナルの可視化と細胞機能
- Author(s)
  齋藤尚亮
- Organizer
  第８９日本生理学会大会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] 内耳有毛細胞におけるRhoファミリー低分子量G蛋白質の役割
- Author(s)
  上山健彦、齋藤尚亮
- Organizer
  日本組織細胞化学会
- Place of Presentation
  松本
- Year and Date
  2014-09-27 – 2014-09-28
- Data Source
  KAKENHI-PUBLICLY-25113715
[Presentation] 創薬ターゲットとしてのジアシルグリセロールキナーゼ
- Author(s)
  白井康仁、齋藤尚亮
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] 中枢神経損傷とRho family GTPases
- Author(s)
  上山健彦、齋藤尚亮
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23659137
[Presentation] Cdc42 is required for maintenance of stereocilia and apical junctional complexes in cochlear hair cells.
- Author(s)
  Ueyama, T., Sakaguchi, H., Goto, A., Hisa, Y., Matsuda, M., Aiba, A. and Saito, N.
- Organizer
  The 37th Naito Conference
- Place of Presentation
  北海道ニセコ
- Year and Date
  2014-07-15 – 2014-07-18
- Data Source
  KAKENHI-PROJECT-25293060

1. SHIRAI Yasuhito (60263399)

# of Collaborated Projects: 18 results

# of Collaborated Products: 40 results
2. UEYAMA Takehiko (80346254)

# of Collaborated Projects: 12 results

# of Collaborated Products: 53 results
3. SAKAI Norio (70263407)

# of Collaborated Projects: 9 results

# of Collaborated Products: 5 results
4. TANAKA Chikako (20025571)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
5. KUNO Takayoshi (50144564)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
6. TANIYAMA Kohtaro (70030898)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
7. NISHIZUKA Yasutomi (10025546)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. ADACHI Naoko (70604510)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
9. SHUNTOH Hisato (70206259)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
10. 柏木香保里 (10372666)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
11. IRIE Kazuhiro (00168535)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
12. TANIGUCHI Taizo (70346253)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
13. KUSUNOKI Masato (50192026)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. SHIRAFUJI Toshihiko (30595765)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
15. ASAOKA Yoshinori (20222565)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. KISHIMOTO Akira (60127363)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KONDO Hisatake (20004723)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. SENBA Emika (00135691)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. YONEDA Yoshihiro (80191667)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. FUJIMOTO Toyoshi (50115929)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. ABE Hiroshi (40151104)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. KONDOH Takeshi (50273769)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. NAGASHIMA Tatsuya (80201680)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. TAMAKI Norihiko (10030941)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. NISHIZAKI Tomoyuki (00221474)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. YAJIMA Yukio (10068489)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. MATSUYAMA Shogo (80243319)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. SANO Akira (30178800)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. OHIGASHI Hajime (80026583)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
30. MATSUO Akinori (20324585)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
31. AIMI Yoshinari (20231756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
32. 米澤一仁 (70283900)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 吉川潮 (40150354)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 小野功貴 (10243297)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 深見泰夫 (00156746)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 向井秀幸 (80252758)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 横山光宏 (40135794)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 米原伸 (00124503)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. 福井泰久 (00181248)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. 山村博平 (90030882)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. 井上圭三 (30072937)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. 淀井淳司 (80108993)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. 天野託 (10294547)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
44. 松林弘明 (60165850)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
45. 山形要人 (20263262)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
46. 柴田洋三郎 (90037482)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
47. 石川春律 (90010058)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
48. 穀内隆 (30178248)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
49. 坂口博史 (00515223)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
50. KAKU Mika

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
51. UEDA Chie

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
52. KASE Hiroshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
53. USAMI Shin-ichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
54. NISHIO Shinya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
55. HISHIKAWA Yoshitaka

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
56. TANAKA SHIGERU

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
57. KOBAYASHI Takeshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
58. 秀和泉

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
59. チョウジョウフナランツオツク

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
60. 鈴木倫毅

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
61. 東田千尋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
62. 戸田達史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SAITO Naoaki 齋藤 尚亮

斉藤 尚亮 サイトウ ナオアキ

齋藤 尚亮 サイトウ ナオアキ

斎藤 尚亮

Research Projects

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Elucidation of amyloid formation mechanism in Spinocerebellar ataxia and its application to drug therapyPrincipal Investigator

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Elucidation of a new differentiation mechanism of beige adipocytes and its application for drug designPrincipal Investigator

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聴・平衡覚器官のイメージング解析～１分子から個体レベルまで～Principal Investigator

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Determination of PKC substrate involved in neurodegenerative diseases and its application for drug designPrincipal Investigator

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聴・平衡覚器官のイメージング解析～１分子から個体レベルまで～Principal Investigator

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Roles of p40phox in Crohn disease and its application for drug developmentPrincipal Investigator

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Production and analysis of model animals for neurodegenerative diseases caused by dysfunction of PKC and their use for drug designPrincipal Investigator

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Mechanism and treatment for the disease caused by the impairment of PKC signalingPrincipal Investigator

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性ホルモンの神経保護作用におけるグリア・ニューロン内情報伝達クロストーク機構Principal Investigator

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SAITO Naoaki 齋藤尚亮

斉藤尚亮サイトウナオアキ

齋藤尚亮サイトウナオアキ

斎藤尚亮