• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Okamoto Yoshitaka  岡本 美孝

ORCIDConnect your ORCID iD *help
… Alternative Names

OKAMOTO Yoshitaka  岡本 美孝

Less
Researcher Number 40169157
Other IDs
External Links
Affiliation (Current) 2025: 千葉大学, 大学院医学研究院, 名誉教授
Affiliation (based on the past Project Information) *help 2016 – 2018: 千葉大学, 大学院医学研究院, 教授
2016: 千葉大学, 医学系研究科, 教授
2012 – 2015: 千葉大学, 医学(系)研究科(研究院), 教授
2014: 千葉大学, 医学研究科, 教授
2014: 千葉大学, 大学院医学研究院, 教授 … More
2011: 千葉大学, 医学系研究科, 教授
2010 – 2011: 千葉大学, 医学, 教授
2007 – 2011: Chiba University, Graduate School of Medicine, Department of Otolaryngology, Professor
2006: Chiba University, Graduate School of Medicine, Professor, 大学院医学研究院, 教授
2002 – 2005: Chiba University, Graduate School of Medicine, Professor, 大学院・医学研究院, 教授
1996 – 2001: Yamanashi Medical University Professor, 医学部, 教授
1993 – 1995: 秋田大学, 医学部, 講師 Less
Review Section/Research Field
Principal Investigator
Otorhinolaryngology / Otorhinolaryngology
Except Principal Investigator
Otorhinolaryngology / Otorhinolaryngology / Production engineering/Processing studies / アレルギー
Keywords
Principal Investigator
nasal allergy / ウイルス / NKT細胞 / 鼻アレルギー / virus / RSウイルス / サイトカイン / 頭頸部癌 / Th2細胞 / Th2サイトカイン … More / アレルギー性鼻炎 / upper respiratory infection / Th2 cell / Th1 cell / cedar pollinosis / allergic rhintis / 鼻粘膜過敏性 / 気道感染 / 上気道感染 / Th1細胞 / スギ花粉症 / polymerase chain reaction / tissve culture / bacteria / Acute otitis media / 中耳炎動物モデル / 核酸増殖法 / ウイルス中和抗体 / 肺炎球菌 / 核酸増幅 / 組織培養 / 気道アレルギー / 細菌 / 急性中耳炎 / transgenic mice / recombinant vacvina virus / respiratory syncytial virus / Th2 cytokine / Th1 cytokine / 感染実験 / ワクチニアウイルス / 鼻アレルギーモデルマウス / IL-10 / 鼻腔免疫 / 抗体投与 / 鼻腔粘膜 / 腸管免疫 / 受動免疫 / トランスジェニックマウス / Th1サイトカイン / chronic sinusitis / cell adhesion molecule / cytokine / nasal mucosa / F糖蛋白 / G糖蛋白 / マウス / トシル酸スプラタスト / ヒト鼻アレルギー / ハウスダスト / 慢性炎症 / アレルギー / 細胞接着分子 / 鼻・副鼻腔 / アジュバンド療法 / 先進医療 / アジュバント療法 / 細胞障害性T細胞 / 悪性黒色腫 / 扁平上皮癌 / 癌免疫療法 / 抗原提示細胞 / 粘膜投与 / 免疫療法 / Th2 細胞 / Th2 サイトカイン / NKT 細胞 / 好酸球性副鼻腔炎 … More
Except Principal Investigator
サイトカイン / メタマテリアル・表面プラズモン / IgE / IL-12 / toll like receptor / Th2 / IgA / NALT / RSウイルス / トランスレーショナル・リサーチ / mesothelin / メソテリン / 標的分子 / 免疫療法 / 唾液腺癌 / キメラ抗原受容体 / ナノマイクロ加工 / 鼻アレルギー / アレルギー / 光線力学治療 / アレルギー性鼻炎 / アミノレブリン酸 / 光線力学的治療 / メタマテラル・表面プラズモン / NKT細胞 / 免疫細胞療法 / がん免疫療法 / 唾液腺がん / がん免疫 / EXiLE / 舌下免疫療法 / ルシフェラーゼ / バイオマーカー / IgG / EXiLE法 / アレルゲン舌下免疫療法 / TNF-alpha / delta T cell / gamma / peptidoglycan / lipopolysaccharide / intestinal microflora / cord blood / TLR2 / CD14 / TLR4 / 自然免疫 / プロバイオティクス / TNF-α / γδT細胞 / ペプチドグリカン / リポポリサッカライド / 腸内細菌 / 臍帯血 / chemokine / cytokine / eosinophil / genotype analyses / preventive medicine / nasal mucosal hyperresponsiveness / IL-4受容体α鎖 / 遺伝子多型 / スギ花粉症 / ケモカイン / 好酸球 / 遺伝子多型解析 / 予防医学 / 鼻過敏症 / RS virus infection / Th l / cell transfer / CD4+T cell / Mast cell / Eosinophil infiltration / Nasal hypersensitivity / Nasal allergy / アレルギーモデルマウス / RSウイルス感染 / Th1 / 細胞移入 / CD4陽性T細胞 / 肥満細胞 / 好酸球浸潤 / 鼻粘膜知覚過敏性 / RS virue / Streptococcus pneumoniae / Haemophilus influenzae / Mucosal immune system / vaccine / Intranasal immunization / P6 / CD4^+T細胞 / マウス / 中耳粘膜 / 鼻粘膜 / 肺炎球菌 / インフルエンザ菌 / 経鼻免疫 / ワクチン / goblet cell / mucus / airway secretion / nitric oxide / 鼻粘膜上皮杯細胞 / 鼻粘膜上皮 / 鼻汁分泌 / 杯細胞 / 一酸化窒素 / Mucosal immunity / Respiratory syncytial virus / Adhesion molecule / Cytokine / Otitis media effusion / PCR法 / 腸管免疫 / 細胞接着分子 / 滲出性中耳炎 / 癌免疫 / マタマテリアル・表面プラズモン / 表面プラズモン / メタマテリアル / ナノ・マイクロ加工 / 記憶免疫 / Th2細胞 / 花粉症 / Th2 細胞 / メモリーT細胞 / 免疫記憶 / 免疫学 / アレルギー・ぜんそく / ぜんそく / 嗅上皮 / BDNF / アデノウイルスベクター Less
  • Research Projects

    (22 results)
  • Research Products

    (97 results)
  • Co-Researchers

    (49 People)
  •  Study of the mechanism and therapeutic biomarkers for sublingual immunotherapy by using the EXiLE method

    • Principal Investigator
      Nakamura Ryosuke
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      National Institute of Health Sciences
  •  Adoptive Immunotherapy using the Lymphocytes transduced with Chmeric Antigen Receptor against Salivary Gland Tumor

    • Principal Investigator
      KUNII Naoki
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Chiba University
  •  Development of photodynamic therapy for the allergic rhinitis

    • Principal Investigator
      SUZUKI TAKESHI
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Chiba University
  •  Plasmonic nanostructures realizing miniaturized infrared spectrometric image-array-sensor for endoscopy

    • Principal Investigator
      Delaunay Jean-Jacques
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Production engineering/Processing studies
    • Research Institution
      The University of Tokyo
  •  light confinement in plasmonic nanocavities for use as biosensor

    • Principal Investigator
      DELAUNAY Jean-Jacques
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Production engineering/Processing studies
    • Research Institution
      The University of Tokyo
  •  Adoptive Immunotherapy using the Lymphocytes transduced with Chimeric Antigen Receptor against Salivary Gland Tumor

    • Principal Investigator
      KUNII Naoki
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Chiba University
  •  Development of adjuvant therapy for head and neck cancer by activation of NKT cells via nasal mucosaPrincipal Investigator

    • Principal Investigator
      Okamoto Yoshitaka
    • Project Period (FY)
      2012 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Chiba University
  •  Breath test sensors for disease screening

    • Principal Investigator
      J-J Delaunay
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Production engineering/Processing studies
    • Research Institution
      The University of Tokyo
  •  Adjuvant cellular immnunotherapy for head and neck cancerPrincipal Investigator

    • Principal Investigator
      OKAMOTO Yoshitaka
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Chiba University
  •  Role of NKT cells in the eosinophilic diseases in upper respiratory tract and approachfor a new treatmentPrincipal Investigator

    • Principal Investigator
      OKAMOTO Yoshitaka
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Chiba University
  •  Seasonal changes in antigen-specific T-helper clone sizes and their memory functions in patients with Japanese cedar pollinosis

    • Principal Investigator
      HORIGUCHI Shigetoshi
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Chiba University
  •  Role of infectious diseases in allergic rhinitisPrincipal Investigator

    • Principal Investigator
      OKAMOTO Yoshitaka
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Chiba University
  •  Function of innate-immune cells in cord blood and development of allergy

    • Principal Investigator
      SHIMOJO Naoki
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      アレルギー
    • Research Institution
      Chiba University
  •  アデノウイルスベクターを用いた神経伸長因子遺伝子導入による鼻粘膜嗅上皮の再生

    • Principal Investigator
      SUZUKI Homare
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Chiba University
  •  Aiming toward effective preventive medicine against Japanese cedar pollinosis : -----Epidemiology, patient investigation, and integrated research including genotype analyses-

    • Principal Investigator
      TERADA Nobuhisa
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Chiba University
  •  Influence of viral infection on the devefepmeat of acute otitis media and approach for treatmentPrincipal Investigator

    • Principal Investigator
      OKAMOTO Yoshitaka
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      CHIBA UNIVERSITY
      山梨医科大学
  •  The mechanism of development of nasal hypersensitivity: Role of T cell and approach to treatment

    • Principal Investigator
      MATSUZAKI Zensei
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Yamanashi Medical University
  •  The mucosal immune system of the upper respiratory tract and development of nasal vaccine for upper respiratory tract infection

    • Principal Investigator
      MOGI Goro
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Oita Medical University
  •  The role of cytokines in varal infection and in allergy in the respiratory tract was evaluated.Principal Investigator

    • Principal Investigator
      OKAMOTO Yoshitaka
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Yamanashi Medical University
  •  The effect of NO in the sesretion from nasal epithelial goblet cells.

    • Principal Investigator
      KAMIJO Atsushi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Yamanashi Medical University
  •  Expression of cytokines and cell adhesion molecules in nasal inflammatory diseases.Principal Investigator

    • Principal Investigator
      OKAMOTO Yoshitaka
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Yamanashi Medical University
      Akita University
  •  The study of the pathogenesis of otitis media with effusion and the role of viral infection.

    • Principal Investigator
      ITO Eiko, SARASHINA Norio
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      AKITA UNIVERSITY

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2005 Other

All Journal Article Presentation Book Other

  • [Book] アレルギー疾患のすべて2016

    • Author(s)
      岡本美孝
    • Total Pages
      367
    • Publisher
      日本医師会
    • Data Source
      KAKENHI-PROJECT-16H05483
  • [Journal Article] Pathogenicity of memory Th2 cells is linked to stage of allergic rhinitis2018

    • Author(s)
      Iinuma T.、Okamoto Y.、Morimoto Y.、Arai T.、Sakurai T.、Yonekura S.、Sakurai D.、Hirahara K.、Nakayama T.
    • Journal Title

      Allergy

      Volume: 73 Issue: 2 Pages: 479-489

    • DOI

      10.1111/all.13295

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08876, KAKENHI-PROJECT-16H05483
  • [Journal Article] An analysis of factors related to the effect of sublingual immunotherapy on Japanese cedar pollen induced allergic rhinitis2018

    • Author(s)
      Yonekura S, Okamoto Y, Sakurai D, Okubo K, Gotoh M, Kaneko S, Konno A.
    • Journal Title

      Allergol. Int.

      Volume: 67 Issue: 2 Pages: 201-208

    • DOI

      10.1016/j.alit.2017.07.005

    • NAID

      130006721780

    • ISSN
      1323-8930, 1440-1592
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K10778, KAKENHI-PROJECT-16H05483
  • [Journal Article] Identification of specifically reduced Th2 cell subsets in allergic rhinitis patients after sublingual immunotherapy2018

    • Author(s)
      1.Ihara F, Saurai D, Yonekura S, Iinuma T, Matsuura A, Morimoto Y, Arai T, Suzuki S, Katayama K, Nakayama T, Okamoto Y
    • Journal Title

      Allergy

      Volume: 73 Issue: 9 Pages: 1823-1832

    • DOI

      10.1111/all.13436

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05483
  • [Journal Article] Immunosuppressive property of submandibular lymph nodes in patients with head and neck tumors: differential distribution of regulatory T cells2018

    • Author(s)
      Sakurai D, Uchida R, Ihara F, Kunii N, Nakagawa T, Chazono H, Hanazawa T, Motohashi S, Okamoto Y
    • Journal Title

      BMC Research Notes

      Volume: 11 Issue: 1 Pages: 479-479

    • DOI

      10.1186/s13104-018-3587-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05483, KAKENHI-PROJECT-17K11376, KAKENHI-PROJECT-17K16892, KAKENHI-PROJECT-18H02892
  • [Journal Article] Deep sequencing-based microRNA expression signatures in head and neck squamous cell carcinoma: dual strands of pre-miR-150 as antitumor miRNAs.2017

    • Author(s)
      Koshizuka K, Hanazawa T, Fukumoto I, Kikkawa N, Okamoto Y, Seki N.
    • Journal Title

      Oncotarget

      Volume: 印刷中 Issue: 18 Pages: 30288-30304

    • DOI

      10.18632/oncotarget.16327

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-16K11224, KAKENHI-PROJECT-17K11375, KAKENHI-PROJECT-17K16893, KAKENHI-PROJECT-15K10801, KAKENHI-PROJECT-16K20229
  • [Journal Article] Definitive carbon-ion radiotherapy for locally advanced parotid gland carcinomas.2017

    • Author(s)
      Koto M, Hasegawa A, Takagi R, Ikawa H, Naganawa K, Mizoe JE, Jingu K, Tsujii H, Tsuji H, Kamada T, Okamoto Y.
    • Journal Title

      Head Neck.

      Volume: 39 Issue: 4 Pages: 724-729

    • DOI

      10.1002/hed.24671

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249081
  • [Journal Article] House dust mite sublingual tablet is effective and safe in patients with allergic rhinitis.2017

    • Author(s)
      Okamoto Y, Fujieda S, Okano M, Yoshida Y, Kakudo S, Masuyama K.
    • Journal Title

      Allergy

      Volume: 72 Issue: 3 Pages: 435-443

    • DOI

      10.1111/all.12996

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05483, KAKENHI-PROJECT-26293368, KAKENHI-PROJECT-15H04987
  • [Journal Article] Dual-receptor (EGFR and c-MET) inhibition by tumor-suppressive miR-1 and miR-206 in head and neck squamous cell carcinoma.2017

    • Author(s)
      Koshizuka K, Hanazawa T, Fukumoto I, Kikkawa N, Matsushita R, Mataki H, Mizuno K, Okamoto Y, Seki N.
    • Journal Title

      Journal of Human Genetics

      Volume: 62 Issue: 1 Pages: 113-121

    • DOI

      10.1038/jhg.2016.47

    • NAID

      40021036343

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-26462596, KAKENHI-PROJECT-15K10800, KAKENHI-PROJECT-15K10801, KAKENHI-PROJECT-16K11224
  • [Journal Article] The microRNA signatures: aberrantly expressed microRNAs in head and neck squamous cell carcinoma.2017

    • Author(s)
      Keiichi Koshizuka, Toyoyuki Hanazawa, Ichiro Fukumoto, Naoko Kikkawa, Yoshitaka Okamoto, Naohiko Seki.
    • Journal Title

      Journal of Human Genetics

      Volume: 62 Issue: 1 Pages: 3-13

    • DOI

      10.1038/jhg.2016.105

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-15K10800
  • [Journal Article] Invariant NKT cells are resistant to circulating CD15(+) myeloid-derived suppressor cells in patients with head and neck cancer.2016

    • Author(s)
      Horinaka A, Sakurai D, Ihara F, Makita Y, Kunii N, Motohashi S, Nakayama T, Okamoto Y.
    • Journal Title

      Cancer Sci.

      Volume: 107 Issue: 3 Pages: 207-16

    • DOI

      10.1111/cas.12866

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-15K20181
  • [Journal Article] Carbon ion radiotherapy for locally advanced squamous cell carcinoma of the external auditory canal and middle ear.2016

    • Author(s)
      Koto M, Hasegawa A, Takagi R, Sasahara G, Ikawa H, Mizoe JE, Jingu K, Tsujii H, Kamada T, Okamoto Y
    • Journal Title

      Head Neck.

      Volume: 38(4) Issue: 4 Pages: 512-6

    • DOI

      10.1002/hed.23905

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249081
  • [Journal Article] Three Cases of Neck Swelling after FNAC (fine-needle aspiration cytology)2016

    • Author(s)
      大塚雄一郎, 根本俊光, 國井直樹, 花澤豊行, 岡本美孝
    • Journal Title

      Nippon Jibiinkoka Gakkai Kaiho

      Volume: 119 Issue: 9 Pages: 1225-1230

    • DOI

      10.3950/jibiinkoka.119.1225

    • NAID

      130005420700

    • ISSN
      0030-6622, 1883-0854
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K20181
  • [Journal Article] Evaluation of the safety and efficacy of carbon ion radiotherapy for locally advanced adenoid cystic carcinoma of the tongue base.2016

    • Author(s)
      Koto M, Hasegawa A, Takagi R, Ikawa H, Naganawa K, Mizoe JE, Jingu K, Tsujii H, Tsuji H, Kamada T, Okamoto Y
    • Journal Title

      Head Neck.

      Volume: 印刷中 Issue: S1

    • DOI

      10.1002/hed.24397

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-26860970
  • [Journal Article] Basal cell adenoma of the parotid gland; MR features and differentiation from pleomorphic adenoma.2016

    • Author(s)
      Mukai H, Motoori K, Horikoshi T, Takishima H, Nagai Y, Okamoto Y, Uno T.
    • Journal Title

      Dentomaxillofac Radiol.

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249081
  • [Journal Article] Long-term outcomes after carbon-ion radiotherapy for oral mucosal malignant melanoma.2016

    • Author(s)
      Nakagawa K, Koto M, Takagi R, Hasegawa A, Ikawa H, Schimozato K, Kamada T, Okamoto Y.
    • Journal Title

      Journal of Medical Case Reports

      Volume: 10:284 Pages: 1-4

    • NAID

      130007397897

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249081
  • [Journal Article] Different Results of IgE Binding- and Crosslinking-Based Allergy Tests Caused by Allergen Immobilization2016

    • Author(s)
      Okamoto-Uchida Y, Nakamura R, Matsuzawa Y, Soma M, Kawakami H, Ishii-Watabe A, Nishimaki-Mogami T, Teshima R, Saito Y.
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 39 Issue: 10 Pages: 1662-1666

    • DOI

      10.1248/bpb.b16-00389

    • NAID

      130005598496

    • ISSN
      0918-6158, 1347-5215
    • URL

      https://pure.teikyo.jp/en/publications/6abb146a-da62-491b-b3e9-a4e794d6f491

    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05483, KAKENHI-PROJECT-15K19168
  • [Journal Article] Th2 cells in health and disease.2016

    • Author(s)
      Nakayama T, Hirahara K, Onodera A, Endo Y, Hosokawa H, Shinoda K, Tumes DJ, Okamoto Y.
    • Journal Title

      Annu Rev Immunol.

      Volume: 35 Issue: 1 Pages: 53-84

    • DOI

      10.1146/annurev-immunol-051116-052350

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05483, KAKENHI-PROJECT-17K08876, KAKENHI-PUBLICLY-16H01352, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-16H06224, KAKENHI-PROJECT-15K08522
  • [Journal Article] A Case of Oropharyngeal Squamous Cell Carcinoma who Developed Sigmoid Colon Perforation after Cetuximab Treatment2016

    • Author(s)
      浜崎佐和子, 國井直樹, 蒔田勇治, 有本昇平, 木谷令, 鈴木猛司, 山崎一樹, 米倉修二, 茶薗英明, 櫻井大樹, 花澤豊行, 岡本美孝
    • Journal Title

      Practica Oto-Rhino-Laryngologica

      Volume: 109 Issue: 11 Pages: 803-808

    • DOI

      10.5631/jibirin.109.803

    • NAID

      130005268091

    • ISSN
      0032-6313, 1884-4545
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K20181
  • [Journal Article] The tumor-suppressive microRNA-23b/27b cluster regulates the MET oncogene in oral squamous cell carcinoma.2016

    • Author(s)
      Fukumoto I, Koshizuka K, Hanazawa T, Kikkawa N, Matsushita R, Kurozumi A, Kato M, Okato A, Okamoto Y, Seki N.
    • Journal Title

      Int J Oncol.

      Volume: 49(3) Issue: 3 Pages: 1119-29

    • DOI

      10.3892/ijo.2016.3602

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-26462596, KAKENHI-PROJECT-15K10800, KAKENHI-PROJECT-15K10801, KAKENHI-PROJECT-16K11224
  • [Journal Article] Basal cell adenoma of the parotid gland; MR features and differentiation from pleomorphic adenoma.2016

    • Author(s)
      Mukai H, Motoori K, Horikoshi T, Takishima H, Nagai Y, Okamoto Y, Uno T.
    • Journal Title

      Dentomaxillofac Radiol.

      Volume: 45(4) Pages: 20150322-20150322

    • Data Source
      KAKENHI-PROJECT-24249081
  • [Journal Article] Initial experience of radiotherapy plus cetuximab for Japanese head and neck cancer patients.2015

    • Author(s)
      Kurokawa M, Watanabe Nemoto M, Harada R, Kobayashi H, Horikoshi T, Kanazawa A, Togasaki G, Abe Y, Chazono H, Hanazawa T, Okamoto Y, Uno T.
    • Journal Title

      J Radiat Res.

      Volume: 56(5) Issue: 5 Pages: 849-55

    • DOI

      10.1093/jrr/rrv038

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249081
  • [Journal Article] The Interleukin-33-p38 Kinase Axis Confers Memory T Helper 2 Cell Pathogenicity in the Airway.2015

    • Author(s)
      Endo, Y., Hirahara, K., Iinuma, T., Shinoda, K., Tumes, D. J., Asou, H. K., Matsugae, N., Obata-Ninomiya, K., Yamamoto, H., Motohashi, S., Oboki, K, Nakae, S., Saito, H., Okamoto, Y., and Nakayama, T.
    • Journal Title

      Immunity

      Volume: 42(2) Issue: 2 Pages: 294-308

    • DOI

      10.1016/j.immuni.2015.01.016

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-24591475, KAKENHI-PROJECT-25893032, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-26870172
  • [Journal Article] Feasibility of carbon ion radiotherapy for locally advanced sinonasal adenocarcinoma.2014

    • Author(s)
      Koto M, Hasegawa A, Takagi R, Sasahara G, Ikawa H, Mizoe JE, Jingu K, Tsujii H, Kamada T, Okamoto Y,Organizing Committee for the Working Group for Head-and-Neck Cancer.
    • Journal Title

      Radiother Oncol.

      Volume: 113(1) Issue: 1 Pages: 60-5

    • DOI

      10.1016/j.radonc.2014.09.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249081
  • [Journal Article] microRNA-504 inhibits cancer cell proliferation via targeting CDK6 in hypopharyngeal squamous cell carcinoma.2014

    • Author(s)
      Kikkawa N, Kinoshita T, Nohata N, Hanazawa T, Yamamoto N, Fukumoto I, Chiyomaru T, Enokida H, Nakagawa M, Okamoto Y, Seki N.
    • Journal Title

      Int J Oncol.

      Volume: 44(6) Issue: 6 Pages: 2085-92

    • DOI

      10.3892/ijo.2014.2349

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-24592590, KAKENHI-PROJECT-25861528
  • [Journal Article] Effects of the dose-volume relationship on and risk factors for maxillary osteoradionecrosis after carbon ion radiotherapy.2014

    • Author(s)
      Sasahara G, Koto M, Ikawa H, Hasegawa A, Takagi R, Okamoto Y, Kamada T.
    • Journal Title

      Radiat Oncol.

      Volume: 9(1) Issue: 1 Pages: 92-92

    • DOI

      10.1186/1748-717x-9-92

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249081
  • [Journal Article] NKT cells as an ideal target for anti-tumor immunotherapy2013

    • Author(s)
      Fujii S, Shimizu K, Okamoto Y, Kunii N, Nakayama T, Motohashi S, Taniguchi M
    • Journal Title

      Front. Immunol

      Volume: 4 Pages: 409-409

    • DOI

      10.3389/fimmu.2013.00409

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23380186, KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-24592083, KAKENHI-PROJECT-23229005
  • [Journal Article] Tumour-suppressive microRNA-29s inhibit cancer cell migration and invasion by targeting laminin-integrin signalling in head and neck squamous cell carcinoma.2013

    • Author(s)
      Kinoshita T, Nohata N, Hanazawa T, Kikkawa N, Yamamoto N, Yoshino H, Itesako T, Enokida H, Nakagawa M, Okamoto Y, Seki N.
    • Journal Title

      Br J Cancer

      Volume: 109 Issue: 10 Pages: 2636-2645

    • DOI

      10.1038/bjc.2013.607

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592505, KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-24592590, KAKENHI-PROJECT-25670694, KAKENHI-PROJECT-25861528
  • [Journal Article] Tumour-suppressive microRNA-874 contributes to cell proliferation through targeting of histone deacetylase 1 in head and neck squamous cell carcinoma.2013

    • Author(s)
      Nohata N, Hanazawa T, Kinoshita T, Inamine A, Kikkawa N, Itesako T, Yoshino H, Enokida H, Nakagawa M, Okamoto Y, Seki N.
    • Journal Title

      Br J Cancer

      Volume: 108 Issue: 8 Pages: 1648-1658

    • DOI

      10.1038/bjc.2013.122

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592505, KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-24592575, KAKENHI-PROJECT-25861528
  • [Journal Article] Tumor suppressive microRNA-133a regulates novel targets: Moesin contributes to cancer cell proliferation and invasion in head and neck squamous cell carcinoma.2012

    • Author(s)
      Kinoshita T, Nohata N, Fuse M, Hanazawa T, Kikkawa N, Fujimura L, Takano H, Yamada Y, Yoshino H, Enokida H, Nakagawa M, Okamoto Y, Seki N.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 418 Pages: 1821-1830

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249081
  • [Journal Article] Actin-related protein 2/3 complex subunit 5 (ARPC5) contributes to cell migration and invasion and is directly regulated by tumor-suppressive microRNA-133a in head and neck squamous cell carcinoma.2012

    • Author(s)
      Kinoshita T, Nohata N, Watanabe-Takano H, Yoshino H, Hidaka H, Fujimura L, Fuse M, Yamasaki T, Enokida H, Nakagawa M, Hanazawa T, Okamoto Y, Seki N.
    • Journal Title

      Int J Oncol.

      Volume: 40 Pages: 1770-1778

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249081
  • [Journal Article] Plectin promotes migration and invasion of cancer cells and is a novel probnostic marker for head and neck squamous cell carcinoma.2012

    • Author(s)
      Katada K,Tomonaga T, Satoh M, Matsushita K, Tonoike Y, Kodera Y, Hanazawa T, Nomura F, Okamoto Y.
    • Journal Title

      Journal of Proteomics.

      Volume: 75 Pages: 1803-1815

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249081
  • [Journal Article] Afibrin glue is a candidate scafford for long-term therapeutic protein expression in spontaneously differentiated adipocytes in vitro.2012

    • Author(s)
      Aoyagi Y,Kuroda M,Asada S,Tanio M,Aso M,Okamoto Y,Saito Y,Bujo H.
    • Journal Title

      Experimental Cell Reseach

      Volume: 318 Pages: 1090-1112

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249081
  • [Journal Article] Migration and immunological reaction after the administration of α-GalCer-pulsed- antigen-presenting cells into the submucosa of patients with head and neck cancer2011

    • Author(s)
      Kurosaki, M., Horiguchi, S., Yamasaki, K., Uchida, Y., Motohashi, S., Nakayama, T., Sugimoto, A., Okamoto, Y
    • Journal Title

      Cancer Immunology and Immunotherapy

      Volume: 60 Pages: 207-215

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390458
  • [Journal Article] Anti-tumor immune responses induced by iNKT cell-based immunotherapy for lung cancer and head and neck cancer2011

    • Author(s)
      Motohashi S, Okamoto Y, Yoshino I, Nakayama T
    • Journal Title

      Clinical Immunology

      Volume: 140 Pages: 167-176

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390458
  • [Journal Article] Nasal submucosal administration of antigen-presenting cells induces effective immunological responses in cancer immunotherapy2011

    • Author(s)
      Okamoto Y, Fujikawa A, Kurosaki M, Yamasaki K, Sakurai D, Horiguchi S, Nakayama T
    • Journal Title

      Advances in Oto-Rhino-Laryngology

      Volume: 72 Pages: 149-152

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390458
  • [Journal Article] Nasal submucosal administration of antigen-presenting cells induces effective immunological responses in cancer immunotherapy2011

    • Author(s)
      Okamoto Y
    • Journal Title

      Oto-Rhino-Laryngology

      Volume: 72 Pages: 149-152

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390458
  • [Journal Article] Induction of NKT cell-specific immune responses in cancer tissues after NKT cell-targeted adoptive immunotherapy2011

    • Author(s)
      Yamasaki, K., Horiguchi, S., Kurosaki, M., Kunii, N., Nagato, K., Hanaoka, H., Shimizu, N., Ueno, N., Yamamoto, S., Taniguchi, M., Motohashi, S., Nakayama, T., Okamoto, Y
    • Journal Title

      Clinical Immunology

      Volume: 138 Pages: 255-265

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390458
  • [Journal Article] The effect of radiotherapy on NKT cells in patients with advanced head and neck cancer2010

    • Author(s)
      Kobayashi, K., Tanaka, Y., Horiguchi, S., Yamamoto, S., Nakayama, T., Sugimoto, A., Okamoto, Y
    • Journal Title

      Cancer Immunology and Immunotherapy

      Volume: 59 Pages: 1503-1509

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390458
  • [Journal Article] 気管食道科からみたone airway,one disease2009

    • Author(s)
      岡本美孝
    • Journal Title

      気管食道科学会会報 60

      Pages: 153-154

    • Data Source
      KAKENHI-PROJECT-19591956
  • [Journal Article] 上気道の粘膜:基礎から臨床へ-鼻アレルギー・頭頸部癌の免疫治療への展開2009

    • Author(s)
      岡本美孝
    • Journal Title

      耳鼻咽喉科・頭頸部外科 81

      Pages: 887-896

    • Data Source
      KAKENHI-PROJECT-21390458
  • [Journal Article] Combination Therapy of In vitro Expanded Natural Killer T Cells and α-Galactosylceramide-pulsed Antigen Presenting Cells in Patients with Recurrent Head and Neck Carcinoma2009

    • Author(s)
      Kumii, N., Horiguchi, S., Motohashi, S., Yamamoto, H., Ueno, N., Yamamoto, S., Sakurai, D., Taniguchi, M., Nakayama, T., Okamoto, Y
    • Journal Title

      Cancer Science

      Volume: 100 Pages: 1092-1098

    • NAID

      10025146740

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390458
  • [Journal Article] Mucosal malignant melanoma of the head and neck treated by carbon ion radiotherapy2009

    • Author(s)
      Yanagi T, Mizoe JE, Hasegawa A, Takagi R, Bessho H, Onda T, Kamada T, Okamoto Y, Tsujii H
    • Journal Title

      International Journal of Radiation Oncology

      Volume: 74 Pages: 15-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390458
  • [Journal Article] Seasonal changes in antigen-specific T-helper clone sizes in patients with Japanese cedar pollinosis : a 2-year study2008

    • Author(s)
      Horiguchi S, Tanaka Y, Uchida T, Chazono H, Okawa T, Sakurai D, Okamoto Y.
    • Journal Title

      Clin Exp Allergy 38(3)

      Pages: 405-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591957
  • [Journal Article] Lowered effectiveness of immunotherapy for cypress pollinosis by using Japanese cedar pollen extract2008

    • Author(s)
      Horiguchi S, Okamoto Y, Yonekura S, Okawa T, Kunii N, Yamamoto H, Sakurai D, Hanazawa T.
    • Journal Title

      Arerugi 57(5)

      Pages: 558-61

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591957
  • [Journal Article] A randomized controlled trial of sublingual immunotherapy for Japanese cedar pollinosis2008

    • Author(s)
      Horiguchi S, Okamoto Y, Yonekura S, Okawa T, Yamamoto H, Kunii N, Sakurai D, Fujimura T, Nakazawa K, Yasueda H.
    • Journal Title

      Int Arch Allergy Immunol. 146(1)

      Pages: 76-84

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591957
  • [Journal Article] Detection of natural killer T cells in the sinus mucosa from asthmatics with chronic sinusitis2007

    • Author(s)
      Yamamoto H, Okamoto Y, Horiguchi S, Kunii N, Yonekura S, Nakayama T.
    • Journal Title

      Allergy 62

      Pages: 1451-1455

    • Data Source
      KAKENHI-PROJECT-19591956
  • [Journal Article] 上気道の急性感染症と慢性感染症との違い2005

    • Author(s)
      岡本 美孝
    • Journal Title

      JOHNS 21

      Pages: 148-150

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591776
  • [Journal Article] Influence of viral infection on the development of nasal hypersensitivity2005

    • Author(s)
      Y.Okamoto, Z.Matsuzaki, T.Matsuoka, S.Endo, H.Yamamoto, H.Chazono, S.Horiguchi, T.Hanazawa
    • Journal Title

      Clinical and Experimental Allergy 35

      Pages: 679-684

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591776
  • [Journal Article] The different characteristics observed between acute and chronic infectious diseases in the upper respiratory infection.2005

    • Author(s)
      Y.Okamoto.
    • Journal Title

      JOHNS 21

      Pages: 148-150

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591776
  • [Journal Article] Influence of viral infection on the development of nasal hypersensitivity.2005

    • Author(s)
      Yoshitaka Okamoto
    • Journal Title

      Clinical and Experimental Allergy 37

      Pages: 674-684

    • Data Source
      KAKENHI-PROJECT-17591776
  • [Journal Article] Present situation of cedar pollinosis in Japan and its immune responses

    • Author(s)
      Okamoto Y, Horiguchi S, YamamotoH, YonekuraS, Hanazawa T.
    • Journal Title

      Allergology International (in press)

    • NAID

      10025109444

    • Data Source
      KAKENHI-PROJECT-19591956
  • [Journal Article] Present situation of cedar pollinosis in Japan and its immune responses

    • Author(s)
      Okamoto Y.
    • Journal Title

      Allergology International (In press)

    • NAID

      10025109444

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591956
  • [Journal Article] 気管食道科とone airway,onedisease

    • Author(s)
      岡本美孝
    • Journal Title

      気管食道科学会会報 (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591956
  • [Presentation] スギ花粉症の舌下免疫療法の奏効性は血清中IgEの架橋能と相関する2019

    • Author(s)
      中村亮介, 秋山晴代, 櫻井大樹, 松澤由美子, 斎藤嘉朗, 岡本美孝
    • Organizer
      日本薬学会第139年会
    • Data Source
      KAKENHI-PROJECT-16H05483
  • [Presentation] セツキシマブによる牛肉アレルギー患者血清中IgE架橋活性の解析2018

    • Author(s)
      中村亮介, 岡本(内田)好海, 千貫祐子, 斎藤嘉朗, 森田栄伸
    • Organizer
      第67回日本アレルギー学会学術大会
    • Data Source
      KAKENHI-PROJECT-16H05483
  • [Presentation] Crosslinking ability of the serum IgE correlates to the effectiveness of allergen immunotherapy for Japanese cedar pollen2018

    • Author(s)
      Nakamura R, Akiyama H, Sakurai D, Matsuzawa Y, Saito Y, Okamoto Y
    • Organizer
      WISC 2018
    • Data Source
      KAKENHI-PROJECT-16H05483
  • [Presentation] 舌下免疫療法実施時における血清中中和抗体活性のin vitro評価法の開発2018

    • Author(s)
      秋山晴代, 中村亮介, 櫻井大樹, 平野吉彬, 根来孝治, 岡本美孝
    • Organizer
      第67回日本アレルギー学会学術大会
    • Data Source
      KAKENHI-PROJECT-16H05483
  • [Presentation] Different responses of basophils to allergen between sensitized-asymptomatic subjects and patients with allergic rhinitis.2017

    • Author(s)
      Okamoto Y, Yonekura S, Arai T, Sakurai D.
    • Organizer
      AAAAI2017
    • Place of Presentation
      アトランタ
    • Year and Date
      2017-03-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05483
  • [Presentation] 頭頸部扁平上皮癌患者における制御性T細胞の機能的分画と臨床的意義2016

    • Author(s)
      伊原史英, 堀中敦史, 蒔田勇治, 國井直樹, 櫻井大樹, 岡本美孝
    • Organizer
      日本頭頸部癌学会
    • Place of Presentation
      ソニックシティ(埼玉県・さいたま市)
    • Year and Date
      2016-06-09
    • Data Source
      KAKENHI-PROJECT-15K20181
  • [Presentation] The functional subsets of regulatory T cells correlate with clinical outcome .2016

    • Author(s)
      Ihara F, Sakurai D, Motohashi S, Kunii N, Okamoto Y.
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-24249081
  • [Presentation] The functional subsets of regulatory T cells correlate with clinical outcome and invariant NKT cells suppression in head and neck cancer patients.2016

    • Author(s)
      Ihara F, Sakurai D, Kunii N, Motohashi S, Okamoto Y.
    • Organizer
      第45回日本免疫学会学術集会
    • Place of Presentation
      沖縄コンベンションセンター(沖縄県宜野湾市)
    • Year and Date
      2016-12-05
    • Data Source
      KAKENHI-PROJECT-24249081
  • [Presentation] A randomized double-blind phase II trial evaluating adjuvant therapy for advanced oro- and hypo-pharyngeal cancer using the injection of alpha-GalCer-loaded DCs into the nasal submucosa.2016

    • Author(s)
      Kunii N, Makita Y, Ihara F, Sakurai D, Motohashi S, Nakayama T, Okamoto Y.
    • Organizer
      第20回日本がん免疫学会総会
    • Place of Presentation
      大阪国際交流センター(大阪府大阪市)
    • Year and Date
      2016-07-27
    • Data Source
      KAKENHI-PROJECT-24249081
  • [Presentation] 制御性T細胞の機能的分類と臨床経過との関連2016

    • Author(s)
      伊原史英, 櫻井大樹, 本橋新一郎, 國井直樹, 岡本美孝
    • Organizer
      日本癌学会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15K20181
  • [Presentation] 中咽頭癌におけるエピゲノム変化とHPV感染の検討2016

    • Author(s)
      中川拓也, 松坂恵介, 高根希世子, 福世真樹, 太田聡, 中谷行雄, 國井直樹, 櫻井大樹, 花澤豊行, 岡本美孝, 金田篤志
    • Organizer
      日本癌学会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15K20181
  • [Presentation] 中下咽頭癌CR例に対するiNKT細胞アジュバント療法の有効性に関するランダム化試験2016

    • Author(s)
      國井直樹, 山崎一樹, 茶薗英明, 花澤豊行, 岡本美孝
    • Organizer
      日本口腔咽頭科学会
    • Place of Presentation
      松江テルサ(島根県・松江市)
    • Year and Date
      2016-09-08
    • Data Source
      KAKENHI-PROJECT-15K20181
  • [Presentation] Current concepts on immune mechanisms of sublingual immunotherapy2016

    • Author(s)
      Okamoto Y.
    • Organizer
      18th Asian Research Symposium of Rhinology
    • Place of Presentation
      クアラルンプール
    • Year and Date
      2016-05-26
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05483
  • [Presentation] Efficacy and safety of S-524101 in mono-sensitized and poly-sensitized patients with allergic rhinitis in Japan Phase 2/3 study2016

    • Author(s)
      Okamoto Y, Fujieda S, Masuyaka K, Okano M, Kakudo M.
    • Organizer
      EAACI2016
    • Place of Presentation
      ウィーン
    • Year and Date
      2016-06-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05483
  • [Presentation] A Randomized Double-blind Phase II Trial Evaluating Adjuvant Therapy for Advanced Oro- and Hypo-pharyngeal Cancer using the Injection of aGalCer-loaded DCs into the Nasal Submucosa.2016

    • Author(s)
      Naoki Kunii, Yuji Makita, Fumie Ihara, Daiju Sakurai, Shinichiro Motohashi, Toshinori Nakayama, Yoshitaka Okamoto.
    • Organizer
      第20回日本がん免疫学会総会
    • Place of Presentation
      大阪国際交流センター(大阪府大阪市)
    • Year and Date
      2016-07-27
    • Data Source
      KAKENHI-PROJECT-24249081
  • [Presentation] Analysis of regulatory T cells in peripheral blood of the patients with Head and Neck cancer and their inhibitory role on NKT cells2015

    • Author(s)
      Ihara, F., Sakurai, D., Motohashi, S., and Okamoto, Y.
    • Organizer
      International Conference of Cancer Immunotherapy and Macrophages 2015
    • Place of Presentation
      Ito Hall, Ito International Research Center, The University of Tokyo
    • Year and Date
      2015-07-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24249081
  • [Presentation] 標準治療後の進行期中・下咽頭癌症例に対するαGalCerパルス樹状細胞療法の有効性に関するランダム二重盲検試験2015

    • Author(s)
      國井直樹、蒔田勇治、伊原史英、内田亮介、佐々原剛、藤川陽、櫻井大樹、岡本美孝
    • Organizer
      日本耳鼻咽喉科免疫アレルギー学会
    • Place of Presentation
      東武レバントホテル(東京都墨田区)
    • Year and Date
      2015-02-27
    • Data Source
      KAKENHI-PROJECT-24249081
  • [Presentation] 標準治療後の進行期中・下咽頭癌症例に対するαGalCerパルス樹状細胞療法の有効性に関するランダム化二重盲検試験2015

    • Author(s)
      國井直樹、蒔田勇治、伊原史英、内田亮介、佐々原剛、藤川陽、櫻井大樹、岡本美孝
    • Organizer
      日本耳鼻咽喉科免疫アレルギー学会
    • Place of Presentation
      東武レバントホテル(東京都墨田区)
    • Year and Date
      2015-02-27
    • Data Source
      KAKENHI-PROJECT-25861526
  • [Presentation] Antigen Specific Immunotherapy Based on Chimeric Antigen Receptor Expressing T Cells Targeted to Salivary Gland Tumor2015

    • Author(s)
      Kunii, N., Makita, Y., Ihara, F., Uchida, R., Fujikawa, A., Motohashi, S., Nakayama, T., and Okamoto, Y.
    • Organizer
      International Conference of Cancer Immunotherapy and Macrophages 2015
    • Place of Presentation
      Ito Hall, Ito International Research Center, The University of Tokyo
    • Year and Date
      2015-07-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24249081
  • [Presentation] Antigen Specific Immunotherapy Based on Chimeric Antigen Receptor Expressing T Cells Targeted to Salivary Gland Tumor2014

    • Author(s)
      Kunii, N., Makita, Y., Ihara, F., Uchida, R., Fujikawa, A., Sakurai, D., Motohashi, S., Nakayama, T. and Okamoto, Y.
    • Organizer
      第43回日本免疫学会学術集会
    • Place of Presentation
      国立京都国際会館(京都府京都市左京区)
    • Year and Date
      2014-12-11
    • Data Source
      KAKENHI-PROJECT-24249081
  • [Presentation] 唾液腺癌に対する抗原特異的T細胞の細胞傷害活性は活性化NKT細胞によって相乗的に増強する2014

    • Author(s)
      蒔田勇治、國井直樹、岡本美孝
    • Organizer
      日本唾液腺学会学術集会
    • Place of Presentation
      文京学院大学(東京都文京区)
    • Year and Date
      2014-12-06
    • Data Source
      KAKENHI-PROJECT-25861526
  • [Presentation] The Antigen Specific Immunotherapy Based on the Chimeric Antigen Receptor Expressing T cells Targeted to Salivary Gland Tumor2014

    • Author(s)
      Naoki KUNII, Yuji MAKITA, Fumie IHARA, Ryosuke UCHIDA, Akira FUJIKAWA, Daiju Sakurai, Shinichiro MOTOHASHI, Toshinori NAKAYAMA and Yoshitaka OKAMOTO
    • Organizer
      日本免疫学会
    • Place of Presentation
      国立京都国際会館(京都市左京区)
    • Year and Date
      2014-12-11
    • Data Source
      KAKENHI-PROJECT-25861526
  • [Presentation] 唾液腺癌に対する抗原特異的T細胞の細胞傷害活性は活性化NKT細胞によって相乗的に増強する2014

    • Author(s)
      蒔田勇治、國井直樹、岡本美孝
    • Organizer
      日本唾液腺学会学術集会
    • Place of Presentation
      文教学院大学(東京都文京区)
    • Year and Date
      2014-12-06
    • Data Source
      KAKENHI-PROJECT-24249081
  • [Presentation] 骨髄系免疫抑制細胞の頭頸部腫瘍における検討2014

    • Author(s)
      堀中 敦史、本橋 新一郎、岡本 美孝
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-09-25
    • Data Source
      KAKENHI-PROJECT-24249081
  • [Presentation] NKT細胞免疫系をターゲットにしたがんの免疫細胞治療ー10年間の臨床研究の成果と今後の展望ー2013

    • Author(s)
      中山俊憲、本橋新一郎、國井直樹、岡本美孝
    • Organizer
      第17回日本がん免疫学会総会
    • Place of Presentation
      ANAクラウンプラザホテル宇部
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249081
  • [Presentation] Phase I/II clinical study of α-galactosylceramide-pulsed antigen presenting cells as adjuvant immunotherapy for patients with head and neck mucosal malignant melanoma after carbon ion radiotherapy.2013

    • Author(s)
      Fujikawa, A., Kunii, N., Horinaka, A., Makita, Y., Uchida, R., Ihara, F., Motohashi, S., Okamoto, Y., and Nakayama, T.
    • Organizer
      第42回日本免疫学会総会学術集会
    • Place of Presentation
      幕張メッセ
    • Data Source
      KAKENHI-PROJECT-24249081
  • [Presentation] NKT cell-targeting therapy for lung cancer and head and neck cancer.2013

    • Author(s)
      Motohashi, S., Kunii, N., Taniguchi, M., Yoshino, I., Okamoto, Y., and Nakayama, T.
    • Organizer
      7th International symposium on CD1 and NKT cells
    • Place of Presentation
      Tours France
    • Data Source
      KAKENHI-PROJECT-24249081
  • [Presentation] 炭素イオン線治療後の頭頸部粘膜悪性黒色腫患者に対するaガラクトシルセラミドパルス抗原提示細胞を用いたアジュバント免疫治療に関する第I/II相臨床研究2013

    • Author(s)
      藤川陽,國井直樹,櫻井大樹,長谷川安都佐,鎌田正,溝江純悦,岡本美孝,本橋新一郎,中山俊憲
    • Organizer
      第17回日本がん免疫学会総会
    • Place of Presentation
      ANAクラウンプラザホテル宇部
    • Data Source
      KAKENHI-PROJECT-24249081
  • [Presentation] 新しい頭頸部癌治療の展望:自然免疫系(NKT細胞)を利用した細胞免疫療法2011

    • Author(s)
      山崎一樹, 茶薗英明, 堀口茂俊, 花澤豊行, 岡本美孝
    • Organizer
      第35回日本頭頸部癌学会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-06-09
    • Data Source
      KAKENHI-PROJECT-21390458
  • [Presentation] NKT cell-based immunotherapy for cancer:Nasal sumucosal administration of antigen-presenting cells may induce effective anti-tumor immune responses2010

    • Author(s)
      岡本美孝
    • Organizer
      第4回千葉大学Global COEシンポジウム
    • Place of Presentation
      千葉
    • Year and Date
      2010-08-20
    • Data Source
      KAKENHI-PROJECT-21390458
  • [Presentation] Phase II study of Activated NKT Cells and α-GalCer-pulsed DCs in Patients with recurrent and operable Head and Neck Carcinoma2010

    • Author(s)
      Yamasaki K, Katada K, Kikkawa N, Yonekura S, Okamoto Y
    • Organizer
      13th KJ Joint Meeting of Otorhinolaryngology Head & Neck Surgery
    • Place of Presentation
      Seoul/ Kore
    • Year and Date
      2010-09-10
    • Data Source
      KAKENHI-PROJECT-21390458
  • [Presentation] Nasal submucosal administration of antigen-presenting cells indued effective immunological response in cancer immunotherap2010

    • Author(s)
      岡本美孝, 藤川陽, 稲嶺絢子
    • Organizer
      第7回国際上気道粘膜・扁桃学会
    • Place of Presentation
      旭川
    • Data Source
      KAKENHI-PROJECT-21390458
  • [Presentation] Nasal submucosal administration of antigen-presenting cells indued effective immunological response in cancer immunotherapy2010

    • Author(s)
      岡本美孝
    • Organizer
      第7回国際上気道粘膜・扁桃学会
    • Place of Presentation
      旭川
    • Data Source
      KAKENHI-PROJECT-21390458
  • [Presentation] 頭頸部扁平上皮癌に対する活性化NKT細胞とα-GalCerパルス抗原提示細胞投与による第二相臨床試験2010

    • Author(s)
      山崎一樹, 堀口茂俊, 藤川陽, 佐々原剛, 米倉修二, 花澤豊行, 岡本美孝
    • Organizer
      第111回日本耳鼻咽喉科学会総会・学術講演会
    • Place of Presentation
      仙台
    • Year and Date
      2010-05-21
    • Data Source
      KAKENHI-PROJECT-21390458
  • [Presentation] 気管食道科とone airway, one disease2008

    • Author(s)
      岡本美孝
    • Organizer
      第60回日本気管食道科学会総会
    • Place of Presentation
      熊本市
    • Year and Date
      2008-11-04
    • Data Source
      KAKENHI-PROJECT-19591956
  • [Presentation] 気管食道科とone airway,onedisease2008

    • Author(s)
      岡本美孝
    • Organizer
      気管食道科学会総会
    • Place of Presentation
      熊本市
    • Year and Date
      2008-11-04
    • Data Source
      KAKENHI-PROJECT-19591956
  • [Presentation] Allergic rhinitis in Japan and it's immune responses2007

    • Author(s)
      Okamoto Y.
    • Organizer
      第57回日本アレルギー学会秋季学術大会プレコングレスカンファランス
    • Place of Presentation
      横浜市
    • Year and Date
      2007-10-31
    • Data Source
      KAKENHI-PROJECT-19591956
  • [Presentation] 慢性副鼻腔炎の病態形成に及ぼす喘息合併の意義2007

    • Author(s)
      山本陛三朗. 堀口茂俊. 岡本美孝
    • Organizer
      第57 回日本アレルギー学会秋季学術大会
    • Place of Presentation
      横浜市
    • Year and Date
      2007-11-01
    • Data Source
      KAKENHI-PROJECT-19591956
  • [Presentation] ユビキチン化抵抗性LATによるT細胞のエフェクター機能の強化

    • Author(s)
      國井直樹、櫻井大樹、岡本美孝
    • Organizer
      第31回日本耳鼻咽喉科免疫アレルギー学会
    • Place of Presentation
      倉敷市芸文館(岡山県)
    • Data Source
      KAKENHI-PROJECT-24249081
  • [Presentation] Enhanced function of redirected human T cells expressing LAT thatis

    • Author(s)
      Naoki Kunii, Shinichiro Motohashi, Kaoru Nagato, Yoshitaka Okamoto, Toshinori Nakayama
    • Organizer
      第16回日本癌免疫学会
    • Place of Presentation
      北海道大学学術交流会館
    • Data Source
      KAKENHI-PROJECT-24249081
  • [Presentation] Enhanced function of primary human T cells electroporated with RNA for LAT that is resistant to ubiquitylation

    • Author(s)
      KUNII Naoki, MOTOHASHI Shinichiro, OKAMOTO Yoshitaka, NAKAYAMA Toshinori
    • Organizer
      第41回日本免疫学会学術集会
    • Place of Presentation
      神戸国際会議場(兵庫県)
    • Data Source
      KAKENHI-PROJECT-24249081
  • [Presentation] ユビキチン化抵抗性LATによるT細胞の機能増強

    • Author(s)
      國井直樹、本橋新一郎、岡本美孝、中山俊憲
    • Organizer
      第71回日本癌学会
    • Place of Presentation
      ロイトン札幌(北海道
    • Data Source
      KAKENHI-PROJECT-24249081
  • []

  • 1.  HORIGUCHI Shigetoshi (30293468)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 14 results
  • 2.  MATSUZAKI Zensei (90283217)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  J-J Delaunay (80376516)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  HANAZAWA Toyoyuki (90272327)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 5.  KUNII Naoki (00456047)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 7 results
  • 6.  ITO Eiko (90006734)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  KAMIJO Atsushi (90252022)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  SUZUKI Homare (10344988)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  TERADA Nobuhisa (70197797)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  SAKURAI Daijyu (10375636)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 10 results
  • 11.  Tabata Hitoshi (00263319)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  MAKITA Yuji (90706722)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 13.  SARASHINA Norio (70235448)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  OKAWA Toru (40344981)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  YAMASAKI Kazuki (00422238)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 16.  NAGATO Keisuke (50546231)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  YANAGIMOTO Shintaro (30463889)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  MATSUOKA Tomokazu (30313810)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  MIZUKOSHI Akihito (00283218)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  TERAKAWA Susumu (50014246)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  MOGI Goro (20035190)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  KIYONO Hiroshi (10271032)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  SUZUKI Masashi (60211314)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  KURONO Yuichi (80153427)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  KAWAUCHI Hideyuki (50161279)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  OGINO Jun (00177156)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  SHIMOJO Naoki (40221303)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  Nakamura Ryosuke (50333357)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 29.  Suzuki Yuji (80222066)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  SUZUKI TAKESHI (20422230)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  YONEKURA Syuji (20400939)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  OKUMA Yusuke (50745825)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  MORIMOTO Yuki (40802575)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  白澤 浩 (00216194)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  関 直彦 (50345013)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 36.  本橋 新一郎 (60345022)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 17 results
  • 37.  福本 一郎 (70748764)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 38.  藤川 茂紀 (60333332)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  前田 悦男 (60644599)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  菊島 一仁 (70242659)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  長田 久夫 (30233505)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 42.  秋山 晴代 (50420229)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 43.  岡本 好海 (40716792)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 12 results
  • 44.  三田 吉郎 (40323472)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 45.  CARL H. June
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 46.  June Carl H.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 47.  FUJII Shinーichiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 48.  平原 潔
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 49.  清水 佳奈子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi