Sakamoto Michiie 坂元亨宇

… Alternative Names

SAKAMOTO Michiie 坂元亨宇

坂元亨宇サカモトミチイエ

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Researcher Number	40221270
Other IDs
Affiliation (Current)	2025: 国際医療福祉大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2014 – 2016: 慶應義塾大学, 医学部, 教授 2003 – 2011: 慶應義塾大学, 医学部, 教授 2001: National Cancer Center Research Institure, Pathology Division, Chief, 研究所・病理部, 部長 2000: 国立がんセンター, 研究所病理部, 部長 1999: 国立がんセンター, 研究所・病理部, 部長 … More 1999: National Cancer Center Research Institute East, Pathology Division, Chief, 支所・臨床病理部, 部長 1998: National Cancer Center Reaearch Institute East, Section Head, 病理部, 室長 1997 – 1998: 国立がんセンター, 研究所病理部, 室長 1997: 国立がんセンター, 研究所・病理部, 室長 1996: 国立がんセンター研究所, 病理部, 室長 1993 – 1995: 国立がんセンター研究所, 病理部, 研究員 1990: 国立がんセンター研究所, 病理部, 研究員 Less
Review Section/Research Field	Principal Investigator Human pathology / Human pathology / Biological Sciences Except Principal Investigator Human pathology / Gastroenterology
Keywords	Principal Investigator 肝細胞癌 / 肝転移 / 大腸癌 / Cortactin / HSP70 / CO-029 / 遺伝子発現解析 / c-Src / 細胞運動性 / 転移 … More / 浸潤 / インテグリン / Rho / 細胞運動 / 肝内転移 / 肝細胞がん / Intrahepatic metastasis / Gene expression profile / Hepatitis C virus / Early hepatocellular carcinoma / Multistep carcinogenesis / Hepatocellular carcinoma / Akt / HMGI / 転移モデル / B型肝炎ウイルス / 腺腫様過形成 / 前癌状態 / 多中心性発癌 / C型肝炎ウイルス / 早期肝細胞癌 / 多段階発癌 / gene expression analysis / Rho kinase / integrin / cell motility / invasion and metastasis / hepatocellular carcinoma / カドヘリン / tetraspanin / VDUP1 / DRH1 / Rhoキナーゼ / 浸潤転移 / 癌 / ERK / サブクラス / シグナル伝達 / 病理学 / 組織幹細胞 / リンパ節転移 / G蛋白共役型受容体 / 腺腫 / GPR49/LGR5 / 結節性 / GPR49/L / 肝癌 / 幹細胞 / 細胞増殖 / LGR5 / GPR49 / CD74 / 悪性度 / 予後因子 / Schwann細胞 / synuclein-Y / プロテオーム / 遺伝子発現プロファイル / 移植モデル / 神経浸潤 / 浸潤性膵管がん / 早期肝細胞がん / 多段階発がん / SCIDマウス / p160ROCK / LPA / 線維芽細胞 / 大腸がん / パキシリン / チロシンリン酸化 / 接着斑 / 索状浸潤 / 接着関連糖鎖 / budding像 / Eカドヘリン / ビメンチン / 高転移性細胞株 / 経門脈性転移 … More Except Principal Investigator シグナル伝達 / c-erbB-2 / チロシンリン酸化 / Tyrosine phosphorylation / Invasion / Cell adhesion system / Signal transduction / Growth factor receptor / β-catenin / 細胞接着因子 / がん浸潤 / 細胞接着分子 / 増殖因子受容体 / βカテニン / signal transduction / tyrosine phosphorylation / integrin / catenin / cadherin / invasion and metastasis / cell adhesion / DNAメチル化 / カドヘリン・カテニン / 多段階発がん / がん間質相互作用 / インテグリン / カテニン / カドヘリン / 浸潤・転移 / 細胞接着 / 肝線維化 / 健康寿命 / 発がん / 脂肪性肝炎 / SOD1ノックアウトマウス / SOD K / 多方向性分化細胞 / 胆管細胞癌 / 四塩化炭素 / DEN / レスベラトロール / 高カロリー(高脂肪)食 / 酸化ストレス / Oマウス / SODK / 免疫組織化学 / 肝細胞癌 / 癌胎児性変化 / テネイシン / フィブロネクチン / RNAスプライシング Less

Establishing the molecular pathology-based subclassification of hepatocellular carcinoma.Principal Investigator
- Principal Investigator
  
  SAKAMOTO Michiie
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Keio University
Expression and functional analyses of G protein-coupled receptor GPR49/LGR5 in human tissues and diseasesPrincipal Investigator
- Principal Investigator
  
  SAKAMOTO Michiie
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Keio University
The role of anti-oxidative enzyme SOD1 on the development of hepatocellular carcinoma from steatohepatitis
- Principal Investigator
  
  SAITO Hidetsugu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
Development of individualized diagnosis for cancer of digestive organPrincipal Investigator
- Principal Investigator
  
  SAKAMOTO Michiie
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
Molecular mechanisms of progression and metastasis of hepatocellular carcinoma and their application on diagnosis and therapy.Principal Investigator
- Principal Investigator
  
  SAKAMOTO Michiie
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Keio University
Molecular mechanisms of intrahepatic metastasis of hepatocellular carcinoma and application for diagnosis and treatmentPrincipal Investigator
- Principal Investigator
  
  SAKAMOTO Michiie
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  NATIONAL CANCER CENTER
肝細胞がんの肝内転移機構の解析Principal Investigator
- Principal Investigator
  
  坂元亨宇
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Human pathology
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
ELUDICATION OF ASSOCIATION AND SIGNAL TRANSDUCTION PATHWAY BETWEEN BETA-KATENIN AND GROWTH FACTOR RECEPTOR AT THE CANCER INVASION
- Principal Investigator
  
  OCHIAI Atsushi
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
ヒト大腸がんの肝転移形成に及ぼす間質反応の意義Principal Investigator
- Principal Investigator
  
  坂元亨宇
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Human pathology
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
ヒト大腸癌浸潤先進部における"Tumor budding"の解析-肝転移機構の解明に向けて-Principal Investigator
- Principal Investigator
  
  坂元亨宇
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Human pathology
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
Intercellular interaction and signal transduction in cancer morphogenesis
- Principal Investigator
  
  HIROHASHI Setsuo
- Project Period (FY)
  1995 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Human pathology
- Research Institution
  National Cancer Center Research Institute
ヒト大腸癌の肝転移機構の解析Principal Investigator
- Principal Investigator
  
  坂元亨宇
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Human pathology
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
ヒト肝細胞がんの経門脈性転移機構の解析Principal Investigator
- Principal Investigator
  
  坂元亨宇
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Human pathology
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
ヒト癌における組織特異的alternative splicingの脱制御の検証
- Principal Investigator
  
  関口清俊
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Fujita Health University

All 2017 2016 2015 2014 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Patent

[Journal Article] Pathological Findings of Nonalcoholic Steatohepatitis and Nonalcoholic Fatty Liver Disease.2017
- Author(s)
  Sakamoto M, Tsujikawa H, Effendi K, Ojima H, Harada K, Zen Y, Kondo F, Nakano M, Kage M, Sumida Y, Hashimoto E, Yamada G, Okanoue T, Koike K.
- Journal Title
  
  Pathology International
  
  Volume: 67 Issue: 1 Pages: 1-7
- DOI
  10.1111/pin.12485
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293081, KAKENHI-PROJECT-26460416
[Journal Article] Serum Wisteria Floribunda Agglutinin-Positive Sialylated Mucin 1 as a Marker of Progenitor/Biliary Features in Hepatocellular Carcinoma.2017
- Author(s)
  Tamaki N, Kuno A, Matsuda A, Tsujikawa H, Yamazaki K, Yasui Y, Tsuchiya K, Nakanishi H, Itakura J, Korenaga M, Mizokami M, Kurosaki M, Sakamoto M, Narimatsu H, Izumi N.
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 244-244
- DOI
  10.1038/s41598-017-00357-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293081, KAKENHI-PROJECT-15K21667, KAKENHI-PROJECT-16K09388
[Journal Article] Early hepatocellular carcinoma with high-grade atypia in small vaguely nodular lesions.2016
- Author(s)
  Ojima H, Masugi Y, Tsujikawa H, Emoto K, Fujii-Nishimura Y, Hatano M, Kawaida M, Itano O, Kitagawa Y, Sakamoto M.
- Journal Title
  
  Cancer Sci.
  
  Volume: 107 Issue: 4 Pages: 543-50
- DOI
  10.1111/cas.12893
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293081
[Journal Article] Elastin Fiber Accumulation in Liver Correlates with the Development of Hepatocellular Carcinoma.2016
- Author(s)
  Yasui Y, Abe T, Kurosaki M, Higuchi M, Komiyama Y, Yoshida T, Hayashi T, Kuwabara K, Takaura K, Nakakuki N, Takada H, Tamaki N, Suzuki S, Nakanishi H, Tsuchiya K, Itakura J, Takahashi Y, Hashiguchi A, Sakamoto M, Izumi N.
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 4 Pages: e0154558-e0154558
- DOI
  10.1371/journal.pone.0154558
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293081
[Journal Article] Comprehensive Immune Profiling of Lung Adenocarcinomas Reveals Four Immunosubtypes with Plasma Cell Subtype a Negative Indicator.2016
- Author(s)
  Kurebayashi Y, Emoto K, Hayashi Y, Kamiyama I, Ohtsuka T, Asamura H, Sakamoto M.
- Journal Title
  
  Cancer Immunol Res.
  
  Volume: 4(3) Issue: 3 Pages: 234-237
- DOI
  10.1158/2326-6066.cir-15-0214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462184, KAKENHI-PROJECT-26293081
[Journal Article] Immunohistochemical molecular analysis indicates hepatocellular carcinoma subgroups that reflect tumor aggressiveness.2016
- Author(s)
  Tsujikawa H, Masugi Y, Yamazaki K, Itano O, Kitagawa Y, Sakamoto M.
- Journal Title
  
  Hum Pathol.
  
  Volume: 50 Pages: 24-33
- DOI
  10.1016/j.humpath.2015.10.014
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293081
[Journal Article] Molecular pathology and malignancy of hepatocellular carcinoma2016
- Author(s)
  Kawaida M, Tsujikawa H, Sakamoto M.
- Journal Title
  
  Nippon Shokakibyo Gakkai Zasshi
  
  Volume: 113 Issue: 5 Pages: 761-766
- DOI
  10.11405/nisshoshi.113.761
- NAID
  130005150382
- ISSN
  0446-6586, 1349-7693
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293081
[Journal Article] Overexpression of adenylate cyclase-associated protein 2 is a novel prognostic marker in malignant melanoma.2015
- Author(s)
  Masugi Y, Tanese K, Emoto K, Yamazaki K, Effendi K, Funakoshi T, Mori M, Sakamoto M.
- Journal Title
  
  Pathol Int.
  
  Volume: 65 Issue: 12 Pages: 627-34
- DOI
  10.1111/pin.12351
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293081
[Journal Article] OATP1B3 expression is strongly associated with Wnt/β-catenin signalling and represents the transporter of gadoxetic acid in hepatocellular carcinoma.2014
- Author(s)
  Ueno A, Masugi Y, Yamazaki K, Komuta M, Effendi K, Tanami Y, Tsujikawa H, Tanimoto A, Okuda S, Itano O, Kitagawa Y, Kuribayashi S, Sakamoto M.
- Journal Title
  
  Journal of Hepatology
  
  Volume: 61 Issue: 5 Pages: 1080-1087
- DOI
  10.1016/j.jhep.2014.06.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293081
[Journal Article] Identification by Differential Tissue Proteome Analysis of Talin-1 as a Novel Molecular Marker of Progression of Hepatocellular Carcinoma2011
- Author(s)
  Kanamori H, Kawakami T, Effendi K, Yamazaki K, Mori T, Ebinuma H, Masugi Y, Du W, Nagasaka K, Ogiwara A, Kyono Y, Tanabe M, Saito H, Hibi T, Sakamoto M
- Journal Title
  
  Oncology
  
  Volume: 80 Pages: 406-415
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390108
[Journal Article] Bmi-1 gene is upregulated in early-stage hepatocellular carcinoma and correlates with ATP-binding cassette transporter B1 (ABCB1) expression.2010
- Author(s)
  Effendi K, Mori T, Komuta M, Masugi Y, Du W, Sakamoto M
- Journal Title
  
  Cancer Sci (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Overexpression of leucine-rich repeat-containing G protein-coupled receptor 5 in colorectal cancer2010
- Author(s)
  Uchida K, Yamazaki K, Fukuma M, Yamada T, Hayashida T, Hasegawa H, Kitajima M, Kitagawa Y, Sakamoto M.
- Journal Title
  
  Cancer Sci (in press)
- NAID
  10026595102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390108
[Journal Article] Endothelin-2 is upregulated in basal cell carcinoma under control of Hedgehog signaling pathway2010
- Author(s)
  Tanese K, Fukuma M, Ishiko A, Sakamoto M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 391 Pages: 486-491
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390108
[Journal Article] Bmi-1 gene is upregulated in early-stage hepatocellular carcinoma and correlates with ATP-binding cassette transporter B1 (ABCB1) expression.2010
- Author(s)
  Effendi K, Mori T, Komuta M, Masugi Y, Du W, Sakamoto M.
- Journal Title
  
  Cancer Sci (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Endothelin-2 is upregulated in basal cell carcinoma under control of Hedgehog signaling pathway2010
- Author(s)
  Tanese K, Fukuma M, Ishiko A, Sakamoto M.
- Journal Title
  
  Biochem Biophys Res Commun. 391
  
  Pages: 486-491
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390108
[Journal Article] Endothelin-2 is upregulated in basal cell carcinoma under control of Hedgehog signaling pathway.2010
- Author(s)
  Tanese K, Fukuma M, Ishiko A, Sakamoto M
- Journal Title
  
  Biochem Biophys Res Commun 391
  
  Pages: 486-491
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Overexpression of leucine-rich repeat-containing G protein-coupled receptor 5 in colorectal cancer.2010
- Author(s)
  Uchida H, Sakamoto M, et al
- Journal Title
  
  Cancer Sci
  
  Volume: 101 Pages: 1731-1737
- NAID
  10026595102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390108
[Journal Article] Molecular diagnosis of multistage hepatocarcinogenesis.2010
- Author(s)
  Sakamoto M, et al.
- Journal Title
  
  Jpn J Clin Oncol.
  
  Volume: 40 Pages: 891-896
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390108
[Journal Article] Molecular diagnosis of multistage hepatocarcinogenesis2010
- Author(s)
  Sakamoto M, Effendi K, Masugi Y
- Journal Title
  
  Jpn J Clin Oncol
  
  Volume: 40(9) Pages: 891-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390108
[Journal Article] Endothelin-2 is upregulated in basal cell carcinoma under control of Hedgehog signaling pathway.2010
- Author(s)
  Tanese K, Fukuma M, Ishiko A, Sakamoto M.
- Journal Title
  
  Biochem Biophys Res Commun. 391
  
  Pages: 486-491
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Overexpression of leucine-rich repeat-containing G protein-coupled receptor 5 in colorectal cancer2010
- Author(s)
  Uchida H, Yamazaki K, Fukuma M, Yamada T, Hayashida T, Hasegawa H, Kitajima M, Kitagawa Y, Sakamoto M
- Journal Title
  
  Cancer Sci
  
  Volume: 101(7) Pages: 1731-7
- NAID
  10026595102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390108
[Journal Article] Intraductal carcinoma component as a favorable prognostic factor in biliary tract carcinoma.2009
- Author(s)
  Ojima H, Kanai Y, Iwasaki M, Hiraoka N, Shimada K, Sano T, Sakamoto Y, Esaki M, Kosuge T, Sakamoto M, Hirohashi S.
- Journal Title
  
  Cancer Sci. 100(1)
  
  Pages: 62-70
- NAID
  10025141316
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Construction of human monoclonal single-chain Fv antibodies against small-cell lung cancer by phage display libraries derived from cell-immunized SCID mice engrafted with human peripheral blood lymphocytes.2009
- Author(s)
  Douguchi J, Hashiguchi A, Sakamoto M
- Journal Title
  
  Proteomics Clin Appl 3
  
  Pages: 1265-1272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Synuclein-gamma is closely involved in perineural invasion and distant metastasis in mouse models and is a novel prognostic factor in pancreatic cancer.2009
- Author(s)
  Hibi T, Mori T, Fukuma M, Yamazaki K, Hashiguchi A, Yamada T, Tanabe M, Aiura K, Kawakami T, Ogiwara A, Kosuge T, Kitajima M, Kitagawa Y, Sakamoto M.
- Journal Title
  
  Clin Cancer Res 15(8)
  
  Pages: 2864-2871
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Construction of human monoclonal single-chain Fvantibodies against small-cell lung cancer by phagedisplay libraries derived from cell-immunized SCID mice engrafted with human peripheral blood lymphocytes.2009
- Author(s)
  Douguchi J, Hashiguchi A, Sakamoto M.
- Journal Title
  
  Proteomics Clin Appl 3
  
  Pages: 1265-1272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Adenylate cyclase-associated protein 1 overexpressed in pancreatic cancers is involved in cancer cell motility.2009
- Author(s)
  Yamazaki K, Takamura M, Masugi Y, Mori T, Du W, Hibi T, Hiraoka N, Ohta T, Ohki M, Hirohashi S, Sakamoto M.
- Journal Title
  
  Lab Invest. 89(4)
  
  Pages: 425-432
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Synuclein-y is closely involved in perineural invasion and distant metastasis in mouse models and is a novel prognostic factor in pancreatic cancer2009
- Author(s)
  Hibi T, Mori T, Fukuma M, Yamazaki K, Hashiguchi A, Yamada T, Tanabe M, Aiura K, Kawakami T, Ogiwara A, Kosuge T, Kitajima M, Kitagawa Y. Sakamoto M
- Journal Title
  
  Clin Cancer Res (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Adenylate cyclase-associated protein 1 overexpressed in pancreatic cancers is involved in cancer cell motility.2009
- Author(s)
  Yamazaki K, Takamura M, Masugi Y, Mori T, Du W, Hibi T, Hiraoka N, Ohta T, Ohki M, Hirohashi S, Sakamoto M
- Journal Title
  
  Lab Invest 89(4)
  
  Pages: 425-432
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Early HCC : diagnosis and molecular markers.2009
- Author(s)
  Sakamoto M.
- Journal Title
  
  J Gastroenterol. 44Suppl19
  
  Pages: 108-111
- NAID
  10024364289
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Adenylate cyclase-associated protein 1 overexpressed in pancreatic cancers is involved in cancer cell motility2009
- Author(s)
  Yamazaki K, Takamura M, Masugi Y, Mori T, Du W, Hibi T, Hiraoka N, Ohta T, Ohki M, Hirohashi S, Sakamoto M
- Journal Title
  
  Lab Invest (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Synuclein-gamma is closely involved in perineural invasion and distant metastasis in mouse models and is a novel prognostic factor in pancreatic cancer.2009
- Author(s)
  Hibi T, Mori T, Fukuma M, Yamazaki K, Hashiguchi A, Yamada T, Tanabe M, Aiura K, Kawakami T, Ogiwara A, Kosuge T, Kitajima M, Kitagawa Y, Sakamoto M
- Journal Title
  
  Clin Cancer Res 15(8)
  
  Pages: 2864-2871
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Establishment of an ovarian metastasis model and possible involvement of E-cadherin down-regulation in the metastasis.2008
- Author(s)
  Kuwabara Y, Yamada T, Yamazaki K, Du W, Banno K, Aoki D, Sakamoto M
- Journal Title
  
  Cancer Sci 99
  
  Pages: 1933-1939
- NAID
  10024011784
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Reconstitution of Schwannian Stroma in Neuroblastomas Using Human Bone Marrow Stromal Cells2008
- Author(s)
  Du W, Hozumi N, Sakamoto M, Hata J, Yamada T
- Journal Title
  
  AmJ Pathol 173
  
  Pages: 1153-1164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] G-Protein-Coupled Receptor GPR49 is Up-regulated inBasal Cell Caricinoma and Promotes Cell Proliferation and Tumor Formation2008
- Author(s)
  Tanese K, Fukuma M, Yamada T, Mori T, Yoshikawa T, Watanabe W, Ishiko A, Amagai M, Nihsikawa T, Sakamoto M
- Journal Title
  
  Am J Pathol 173
  
  Pages: 835-843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Histopathological features and prognostic significance of the micropapillary pattern in lung adenocarcinoma.2008
- Author(s)
  Kamiya K, Hayashi Y, Douguchi J, Hashiguchi A, Yamada T, Izumi Y, Watanabe M, Kawamura M, Horinouchi H, Shimada N, Kobayashi K, Sakamoto M
- Journal Title
  
  Mod Pathol 21
  
  Pages: 992-1001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Expression Profile of Early Lung Adenocarcinoma: Identification of MRP3 as a Molecular Marker for Early Progression.2008
- Author(s)
  Hanada S, Maeshima A, Matsuno Y, Ohta T, Ohki M, Yoshida T, Hayashi Y, Yoshizawa Y, Hirohashi S, Sakamoto M
- Journal Title
  
  J Pathol 216
  
  Pages: 75-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Histopathological features and prognostic significance of the micropapillary pattern in lung adenocarcinoma2008
- Author(s)
  Kamiya K, Hayashi Y, Douguchi J, Hashiguchi A, Yamada T, Izumi Y, Watanabe M, Kawamura M, Horinouchi H, Shimada N, Kobayashi K, Sakamoto M
- Journal Title
  
  Mod Pathol 21
  
  Pages: 992-1001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Establishment of an ovarian metastasis model and possible involvement of E-cadherin down-regulation in the metastasis2008
- Author(s)
  Kuwabara Y, Yamada T, Yamazaki K, Du W, Banno K, Aoki D, Sakamoto M
- Journal Title
  
  Cancer Sci 99
  
  Pages: 1933-1939
- NAID
  10024011784
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] G-Protein-Coupled Receptor GPR49 is Up-regulated in Basal Cell Caricinoma and Promotes Cell Proliferation and Tumor Formation.2008
- Author(s)
  Tanese K, Fukuma M, Yamada T, Mori T, Yoshikawa T, Watanabe W, Ishiko A, Amagai M, Nihsikawa T, Sakamoto M
- Journal Title
  
  Am J Pathol 173
  
  Pages: 835-843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Gene therapy of liver timors with human liver-specific nanoparticles2007
- Author(s)
  Iwasaki Y, Ueda M, Yamada T, Kondo A, Seno M, Tanizawa K, Kuroda S, Sakamoto M, Kitajima M
- Journal Title
  
  Cancer Gene Therapy 14
  
  Pages: 74-81
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Specific Expression of Hepatocyte Nuclear Factor。1Bin theOvarian Clear Cell Adenocarcinoma and its Application to Cytological Diagnosis.2007
- Author(s)
  Higashiguchi A, Yamada T, Susumu N, Mori T, SuzukiA, Aoki D, Sakamoto M
- Journal Title
  
  Cancer Sci 98
  
  Pages: 387-391
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Specific Expression of Hepatocyte Nuclear Factor-1 β in the Ovarian Clear Cell Adenocarcinoma and its Application to Cytological Diagnosis2007
- Author(s)
  Higashiguchi A, Yamada T, Susumu N, Mori T, Suzuki A, Aoki D, Sakamoto M
- Journal Title
  
  Cancer Sci 98
  
  Pages: 387-391
- NAID
  10019481758
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Efficient immortalization of primary human cells by p16INK4a-specific short hairpin RNA or Bmi-1, combined with introduction of hTERT.2007
- Author(s)
  Haga K, Ohno S, Yugawa T, Narisawa-Saito M, FujitaM, Sakamoto M, GallowayDA, Kiyono T
- Journal Title
  
  Cancer Sci 98
  
  Pages: 147-154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Specific Expression of Hepatocyte Nuclear Factor-1βin the Ovarian Clear Cell Adenocarcinoma and its Application to Cytological Diagnosis.2007
- Author(s)
  Higashiguchi A, Yamada T, Susumu N, Mori T, Suzuki A, Aoki D, Sakamoto M
- Journal Title
  
  Cancer Sci 98
  
  Pages: 387-391
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Establishment of a novel childhood acute myeloid leukemia cell line, KOPM-88, containing partial tandem duplication of theMLL gene and an in vivo model for childhood acute myeloid leukemia using NOD/SCID mice.2007
- Author(s)
  Hayashi M, Kondoh K, Nakata Y; Kinoshita A, ]Mori T, Takahashi T, Sakamoto M, Yamada T:
- Journal Title
  
  Br J Haematol 137
  
  Pages: 221-232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Gene therapy of liver timors with human liver-specific nanoparticles.2007
- Author(s)
  Iwasaki Y, Ueda M, Yamada T, Kondo A, Seno M, Tanizawa K, Kuroda S, Sakamoto M. Kitaiima M
- Journal Title
  
  Cancer Gene Therapy 14
  
  Pages: 74-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Efficient immortalization of primary human cells by p16INK4a-specific short hairpin RNA or Bmi-1, combined with introduction of hTERT2007
- Author(s)
  Haga K, Ohno S, Yugawa T, Narisawa-Saito M, Fujita M, Sakamoto M, Galloway DA, Kiyono T
- Journal Title
  
  Cancer Sci 98
  
  Pages: 147-154
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Establishment of Perineural Invasion Models and Analysis of Gene Expression Revealed an Invariant Chain (CD74) as a Possible Molecule involved in Perineural Invasion in Pancreatic Cancer2006
- Author(s)
  Koide N, Yamada T, Shibata R, Mori T, Fukuma M, Yamazaki K, Aiura K, Shimazu M, Hirohashi S, Nimura Y, Sakamoto M
- Journal Title
  
  Clin Cancer Res 12(8)
  
  Pages: 2419-2426
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Overexpression of cyclase-associated protein 2 in multistage hepatocarcinogenesis2006
- Author(s)
  Shibata H, Mori T, Du W, Chuma M, Gotoh M, Shimazu M, Ueda M, Hirohashi S, Sakamoto M
- Journal Title
  
  Ciln Cancer Res 12(18)
  
  Pages: 5363-5368
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Establishment of Perineural Invasion Models and Analysis of Gene Expression Revealed an Invariant Chain (CD74) as a Possible Molecule involved in Perineural Invasion in Pancreatic Cancer.2006
- Author(s)
  Koide N, Yamada T, Shibata R, Mori T, Fukuma M, Yamazaki K, Aiura K, Shimazu M, Hirohashi S, Nimura Y, Sakamoto M
- Journal Title
  
  Clin Cancer Res 12(8)
  
  Pages: 2419-2426
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] CT Evalution of the Progression of Hypoattenuating Nodular Lesions in Virus-Related Chronic liver Disease2006
- Author(s)
  Takaysu K, Muramatsu Y, Mizuguchi Y, Okusaka T, Shimada K, Tkayama T, Sakamoto M
- Journal Title
  
  AJR 187
  
  Pages: 454-463
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Overexpression of cyclase-associated protein 2 in multistage hepatocarcinogenesis.2006
- Author(s)
  Shibata R, Mori T, Du W, Chuma M, Gotoh M, Shimazu M, Ueda M, Hirohashi S, Sakamoto M
- Journal Title
  
  Clin Cancer Res 12(18)
  
  Pages: 5363-5368
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Multistep and multicentric development of hepatocellular carcinoma : histological analysis of 980 resected nodules.2005
- Author(s)
  Oikawa T, Ojima H, Yamasaki S, Takayama T, Hirohashi S, Sakamoto M.
- Journal Title
  
  J Hepatol. 42
  
  Pages: 225-229
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390118
[Journal Article] Domain-specific function of ShcC docking protein in neuroblastoma cells.2005
- Author(s)
  Miyake I, Hakomori Y, Misu Y, Nakadate H, Matsuura N, Sakamoto M, Sakai R
- Journal Title
  
  Oncogene 24
  
  Pages: 3206-3215
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Akt Phosphorylation is a risk factor for early disease recurrence and poor prognosis in hepatocellular carcinoma.2005
- Author(s)
  Nakanishi K, Sakamoto M, Yamasaki S, Todo S, Hirohashi S
- Journal Title
  
  Cancer 103
  
  Pages: 307-312
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390118
[Journal Article] Akt Phosphorylation is a risk factor for early disease recurrence and poor prognosis in hepatocellular caricinoma2005
- Author(s)
  Nakanishi K, Sakamoto M, Yamasaki S, Todo S, Hirohashi S
- Journal Title
  
  Cancer 103
  
  Pages: 307-312
- Data Source
  KAKENHI-PROJECT-15390118
[Journal Article] Akt Phosphorylation is a risk factor for early disease recurrence and poor prognosis in hepatocellular caricinoma.2005
- Author(s)
  Nakanishi K, Sakamoto M, Yamasaki S, Todo S, Hirohashi S
- Journal Title
  
  Cancer 103
  
  Pages: 307-312
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390118
[Journal Article] Multistep and multicentric development of hepatocellular carcinoma : histological analysis of 980 resected nodules2005
- Author(s)
  Oikawa T, Ojima H, Yamasaki S, Takayama T, Hirohashi S, Sakamoto M.
- Journal Title
  
  J.Hepatol 42
  
  Pages: 225-229
- Data Source
  KAKENHI-PROJECT-15390118
[Journal Article] Clinical and pathological significance of activation of signal trnansducer and activator of transcription 3 in prostate cancer.2005
- Author(s)
  Horinaga M, Okita H, Nakashima J, Kanao K, Sakamoto M, Murai M
- Journal Title
  
  Urology 66
  
  Pages: 671-675
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Proposal of histological criteria for intraepithelial atypical/proliferative biliary epithelial lesions of the bile duct in hepatolithiasis with respect to cholangiocarcinoma : Preliminary report based on interobserver agreement.2005
- Author(s)
  Yoh Z, Aishima S, Ajioka Y, Haratake J, Kage M, Kondo F, Nimura Y, Sakamoto M, Sasaki M, Shimamatsu K, Wakasa K, Young N.P, Ming F.C, Atomi Y, Nakanuma Y
- Journal Title
  
  Pathol Int 55
  
  Pages: 180-188
- NAID
  10016474999
- Data Source
  KAKENHI-PROJECT-15390118
[Journal Article] Akt Phosphorylation is a risk factor for early disease recurrence and poor prognosis in hepatocellular caricinoma.2005
- Author(s)
  Nakanishi K, Sakamoto M, Yamasaki S, Todo S, Hirohashi S
- Journal Title
  
  Cancer 103
  
  Pages: 307-312
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Multistep and multicentric development of hepatocellular carcinoma : histological analysis of 980 resected nodules.2005
- Author(s)
  Oikawa T, Ojima H, Yamasaki S, Takayama T, Hirohashi S, Sakamoto M.
- Journal Title
  
  J Hepatol 42
  
  Pages: 225-229
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Proposal of histological criteria for intraepithelial atypical/ proliferative biliary epithelial lesions of the bile duct in hepatolithiasis with respect to cholangiocarcinoma : Preliminary report based on interobserver agreement.2005
- Author(s)
  Yoh Z, Aishima S, Ajioka Y, Haratake J, Kage M, Kondo F, Nimura Y, Sakamoto M, Sasaki M, Shimamatsu K, Wakasa K, Young N.P, Ming F.C, Atomi Y, Nakanuma Y
- Journal Title
  
  Pathol Int 55
  
  Pages: 180-188
- NAID
  10016474999
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Multistep and multicentric development of hepatocellular carcinoma : histological analysis of 980 resected nodules.2005
- Author(s)
  Oikawa T, Ojima H, Yamasaki S, Takayama T, Hirohashi S, Sakamoto M
- Journal Title
  
  J. Hepatol. 42
  
  Pages: 225-229
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390118
[Journal Article] Multistep and multicentric development of hepatocellular carcinoma : histological analysis of 980 resected nodules.2005
- Author(s)
  Oikawa T, Ojima H, Yamasaki S, Takayama T, Hirohashi S, Sakamoto M.
- Journal Title
  
  J Hepatol 42
  
  Pages: 225-229
- Data Source
  KAKENHI-PROJECT-15390118
[Journal Article] Multistep and multicentric development of hepatocellular carcinoma: histological analysis of 980 resected nodules.2005
- Author(s)
  Oikawa T, Ojima H, Yamasaki S, Takayama T, Hirohashi S, Sakamoto M
- Journal Title
  
  J Hepatol 42
  
  Pages: 225-229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015042
[Journal Article] Overexpression of cortactin is involved in motility and metastasis of hepatocellular carcinoma.2004
- Author(s)
  Chuma M, Sakamoto M, Yasuda J, Fujii G, Nakanishi K, Tsuchiya A, Ohta T, Asaka M, Hirohashi S
- Journal Title
  
  J Hepatol 41(4)
  
  Pages: 629-636
- Data Source
  KAKENHI-PROJECT-15390118
[Journal Article] Expression profiling in hepatocellular carcinoma with intrahepatic metastasis : identification of high-mobility group I (Y) protein as a molecular marker of hepatocellular carcinoma metastasis.2004
- Author(s)
  Chuma M, Saeki N, Yamamoto Y, Ohta T, Asaka M, Hirohashi S, Sakamoto M.
- Journal Title
  
  Keio J.Med. 53
  
  Pages: 90-97
- NAID
  10013148354
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390118
[Journal Article] Expression profiling in hepatocellular carcinoma with intrahepatic metastasis : identification of high-mobility group I(Y) protein as a molecular marker of hepatocellular carcinoma metastasis.2004
- Author(s)
  Chuma M, Saeki N, Yamamoto Y, Ohta T, Asaka M, Hirohashi S, Sakamoto M
- Journal Title
  
  Keio J.Med 53
  
  Pages: 90-97
- NAID
  10013148354
- Data Source
  KAKENHI-PROJECT-15390118
[Journal Article] Expression profiling in hepatocellular carcinoma with intrahepatic metastasis : identification of high-mobility group I(Y) protein as a molecular marker of hepatocellular carcinoma metastasis.2004
- Author(s)
  Chuma M, Saeki N, Yamamoto Y, Ohta T, Asaka M, Hirohashi S, Sakamoto M
- Journal Title
  
  Keio J. Med. 53
  
  Pages: 90-97
- NAID
  10013148354
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390118
[Journal Article] Overexpression of cortactin is involved in motility and metastasis of hepatocellular carcinoma.2004
- Author(s)
  Chuma M, Sakamoto M, Yasuda J, Fujii G, Nakanishi K, Tsuchiya A, Ohta T, Asaka M, Hirohashi S
- Journal Title
  
  J Hepatol. 41(4)
  
  Pages: 629-36
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390118
[Journal Article] Expression profiling in multistage hepatocarcinogenesis : identification of HSP70 as a molecular marker of early hepatocellular carcinoma.2003
- Author(s)
  Chuma M, Sakamoto M, Yamazaki K, Ohta T, Ohki M, Asaka M, Hirohashi S
- Journal Title
  
  Hepatology 37
  
  Pages: 198-207
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390118
[Journal Article] Possible involvement of tetraspanin CO-029 in hematogenous intrahepatic metastasis of liver cancer cells.2003
- Author(s)
  Kanetaka K, Sakamoto M, Yamamoto Y, Takamura M, Kanematsu T, Hirohashi S
- Journal Title
  
  J. Gastroenterol. Hepatol. 18
  
  Pages: 1309-1314
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390118
[Journal Article] EBP50, a β-catenin-associating protein, enhances Wnt signaling and is over-expressed in hepatocellular carcinoma.2003
- Author(s)
  Shibata T, Chua M, Kokubu A, Sakamoto M, Hirohashi S
- Journal Title
  
  Hepatology 38
  
  Pages: 178-186
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390118
[Journal Article] EBP50, a β-catenin-associating protein, enhances Wnt signaling and is over-expresseed in hepatocellular carcinoma.2003
- Author(s)
  Shibata T, Chuma M, Kokubu A, Sakamoto M, Hirohashi S.
- Journal Title
  
  Hepatology 38
  
  Pages: 178-186
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390118
[Journal Article] Possible involvement of tetraspanin CO-029 in hematogenous intrahepatic metastasis of liver cancer cells.2003
- Author(s)
  Kanetaka K, Sakamoto M, Yamamoto Y, Takamura M, Kanematsu T, Hirohashi S.
- Journal Title
  
  J.Gastroenterol.Hepatol. 18
  
  Pages: 1309-1314
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390118
[Journal Article] Overexpression of orphan G protein-coupled receptor, Gpr49, in human hepatocellular carcinomas with ss-catenin mutations.2003
- Author(s)
  Yamamoto Y, Sakamoto M, Fujii G, Tsuiji H, Kanetaka K, Asaka M, Hirohashi S.
- Journal Title
  
  Hepatology 37
  
  Pages: 528-533
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390118
[Journal Article] Overexpression of orphan G protein-coupled receptor, Gpr49, in human hepatocellular carcinomas with β-catenin mutations.2003
- Author(s)
  Yamamoto Y, Sakamoto M, Fujii G, Tsuiji H, Kanetaka K, Asaka M, Hirohashi S
- Journal Title
  
  Hepatology 37
  
  Pages: 528-533
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390118
[Journal Article] Expression profiling in multistage hepatocarcinogenesis : identification of HSP70 as a molecular marker of early hepatocellular carcinoma.2003
- Author(s)
  Chuma M, Sakamoto M, Yamazaki K, Ohta T, Ohki M, Asaka M, Hirohashi S.
- Journal Title
  
  Hepatology 37
  
  Pages: 198-207
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390118
[Journal Article] Establishment of Perineural Invasion Models and Analysis of Gene Expression Revealed an Invariant Chain (CD74) as a Possible Molecule involved in Perineural Invasion in Pancreatic Cancer
- Author(s)
  Koide N, Yamada T, Shibata R, Mori T, Fukuma M, Yamazaki K, Aiura K, Shimazu M, Hirohashi S, Nimura Y, Sakamoto M.
- Journal Title
  
  Clin Cancer Res (in press)(印刷中)
- Data Source
  KAKENHI-PROJECT-17015042
[Patent] 血中のCAP2の測定方法、肝臓疾患の検出方法及び血中CAP2測定用検出キット2009
- Inventor(s)
  坂元亨宇, 他2名
- Industrial Property Rights Holder
  坂元亨宇, 他2名
- Industrial Property Number
  2009-060966
- Filing Date
  2009-03-13
- Data Source
  KAKENHI-PROJECT-17015042
[Patent] Hedgehogシグナル活性調節剤、細胞増殖調節剤及びその使用方法2006
- Inventor(s)
  坂元亨宇, 他2名
- Industrial Property Rights Holder
  坂元亨宇, 他2名
- Industrial Property Number
  2006-317576
- Filing Date
  2006-11-24
- Data Source
  KAKENHI-PROJECT-17015042
[Presentation] Integtegrative pathologic and molecular approach for HCC diagnosis2011
- Author(s)
  Michiie Sakamoto
- Organizer
  APASL 2^<nd> Hepatocellular Carcinoma Conference
- Place of Presentation
  Jeju, Korea
- Data Source
  KAKENHI-PROJECT-21390108

1. FUKUMA Mariko (60101995)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
2. OCHIAI Atsushi (60183034)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. KANAI Yae (00260315)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. SAITO Hidetsugu (80186949)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. TSUBOTA Kazuo (40163878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. HIROHASHI Setsuo (70129625)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. YAMADA Tesshi (30221659)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TSUDA Hitoshi (70217321)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. NAKANISHI Hiroyuki (10260316)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. FUJII Gen (90321877)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. HASHIGUTI Akinori (50276218)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. DU Wenlin (90348798)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. SHIBATA Rie (00365230)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. 関口清俊 (50187845)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 小山文隆 (40194641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 野口雅之 (00198582)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. TAKANO Kakuko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. YAMAZAKI Ken

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
19. EFFENDI Kathryn

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
20. 前田利長

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 神山育男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sakamoto Michiie 坂元 亨宇

SAKAMOTO Michiie 坂元 亨宇

坂元 亨宇 サカモト ミチイエ

Research Projects

Research Products

Co-Researchers

Establishing the molecular pathology-based subclassification of hepatocellular carcinoma.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Expression and functional analyses of G protein-coupled receptor GPR49/LGR5 in human tissues and diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of anti-oxidative enzyme SOD1 on the development of hepatocellular carcinoma from steatohepatitis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of individualized diagnosis for cancer of digestive organPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms of progression and metastasis of hepatocellular carcinoma and their application on diagnosis and therapy.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanisms of intrahepatic metastasis of hepatocellular carcinoma and application for diagnosis and treatmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

肝細胞がんの肝内転移機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ELUDICATION OF ASSOCIATION AND SIGNAL TRANSDUCTION PATHWAY BETWEEN BETA-KATENIN AND GROWTH FACTOR RECEPTOR AT THE CANCER INVASION

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒト大腸がんの肝転移形成に及ぼす間質反応の意義Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒト大腸癌浸潤先進部における"Tumor budding"の解析-肝転移機構の解明に向けて-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Intercellular interaction and signal transduction in cancer morphogenesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒト大腸癌の肝転移機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒト肝細胞がんの経門脈性転移機構の解析Principal Investigator

Principal Investigator

Sakamoto Michiie 坂元亨宇

SAKAMOTO Michiie 坂元亨宇

坂元亨宇サカモトミチイエ