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Horimoto Katsuhisa  堀本 勝久

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HORIMOTO Katsuhisa  堀本 勝久

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Researcher Number 40238803
External Links
Affiliation (Current) 2022: 国立研究開発法人産業技術総合研究所, 情報・人間工学領域, 招聘研究員
2022: ソシウム株式会社, 研究開発本部, 部門長
Affiliation (based on the past Project Information) *help 2021 – 2022: 国立研究開発法人産業技術総合研究所, 情報・人間工学領域, 招聘研究員
2019 – 2020: 国立研究開発法人産業技術総合研究所, 生命工学領域, 招聘研究員
2017 – 2018: 国立研究開発法人産業技術総合研究所, 生命工学領域, 副研究センター長
2017: 国立研究開発法人産業技術総合研究所, 創薬分子プロファイリング研究センター, 副研究センター長
2016: 国立研究開発法人産業技術総合研究所, 創薬分子プロファイル研究センター, 副センター長 … More
2015: 国立研究開発法人産業技術総合研究所, 創薬分子プロファイリング研究センター, 副研究センター長
2014: 独立行政法人産業技術総合研究所, 創薬分子プロファイリング研究センター, 副センター長
2012 – 2013: 独立行政法人産業技術総合研究所, 生命情報工学研究センター, 研究チーム長
2011: 産業技術総合研究所, 生命情報工学研究センター, 研究チーム長
2009: 産業技術総合研究所, 生命情報工学研究センター, 研究チーム長
2006 – 2009: 独立行政法人産業技術総合研究所, 生命情報工学研究センター, 研究チーム長
2007: 独立行政法人産業技術総合研究所, 生物情報工学研究センター, 研究チーム長
2007: National Institute of Advanced Industrial Science and Technology, 独立行政法人産業技術総合研究所・生命情報工学研究センター, 研究チーム長
2005: 東京大学, 医科学研究所, 特任教授
2003 – 2004: 東京大学, 医科学研究所, 科学技術振興特任教員
2003: 東京大学, 医科学研究所, 科学技術振興特任教員(常勤形態)
2002: 東京大学, 医科学研究所・科学技術振興特任教員(常勤)
2000 – 2001: 佐賀医科大学, 医学部, 助教授 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / 基礎ゲノム科学
Except Principal Investigator
Gastroenterology / Statistical science / 基礎ゲノム科学 / Basic Section 53010:Gastroenterology-related / Medium-sized Section 53:Organ-based internal medicine and related fields / Basic Section 53030:Respiratory medicine-related
Keywords
Principal Investigator
遺伝子配置 / ネットワーク / 遺伝子制御 / ゲノム比較 / ゲノム重複 / 統計解析 / ゲノム / グラフィカル・モデル / 遺伝子制御ネットワーク / ゲノム進化 … More / 環状ゲノム / 遺伝子発現プロファイル / 蛋白質相互作用 / グラフィカル・ガウシアン・モデル / タンパク質相互作用 / Directional Statistics / Spatial Statistics / 線形ゲノム / 細菌ゲノム / 酵母ゲノム / 線形クロモゾーム / 構造比較 / ウェブサイト / 遺伝子制御推定 / 蛋白質相互作用推定 / トリプトファン生合成 / SOS応答 / グラフィカル連鎖モデル / 蛋白質相互作用ネットワーク / オペロン予測 / Path Consistency Algorithm / 計算代数 / 限定記号消去 / 生体生命情報学 / マイクロアレイ / プロテオーム / システム生物学 / ネットワーク解析 / 記号計算 / グラフィカルモデル / 計算機代数 / パラメータ最適化 / 国際研究者交流 / 多国籍 / 統計的因果推定 / 肝がん進展過程 / 統計因果推論 / ゲノム情報 / ゲノム構造比較 / クロモゾーム構造比較 / orthologous遺伝子 / paralogous遺伝子 / paraloous遺伝子 / 空間統計 / クロモゾーム構造 / genome structure comparison / genome duplication / chromosome comparison / gene configuration / orthologous genes / paralogous genes … More
Except Principal Investigator
遺伝子発現 / C型肝炎ウイルス / 治療抵抗性 / IL28B / 肝癌 / 癌 / マイクロアレイ / マルコフ連鎖モンテカルロ法 / トーリックイデアル / グレブナー基底 / 条件つき検定 / 超平面配置 / 条件付き検定 / 次世代シーケンサー / TSS-Seq法 / 転写頻度 / Quality Scores / 配列度数修正 / プロモータ解析 / 組織特異性 / 遺伝子分類 / 転写制御 / 発生の制御 / 細胞学 / 確率モデル / 確立モデル / IFN / C型慢性肝炎 / インターフェロン / 肝内遺伝子発現 / 肝炎 / 自然免疫 / 肝浸潤リンパ球 / C型肝炎 / 肝細胞癌 / ゲノム / 血管内皮 / shear stress / メチル化 / 大腸癌予防薬 / 大腸腺腫 / オルガノイド / SSA/P / 予防薬 / 癌予防 / 腺腫 / Connectivity map解析 / 薬理学 / 非アルコール性脂肪性肝炎 / リン酸化 / プロテインアレイ / 肝微小環境 / 類洞内皮細胞 / Sema6A / 肝再生 / 線維化 / 免疫プレシジョンメディシン / CD4 T細胞 / PD-1阻害薬 / 抗CTLA-4抗体 Less
  • Research Projects

    (19 results)
  • Research Products

    (82 results)
  • Co-Researchers

    (34 People)
  •  Development of immunoprecision medicine for lung cancer using liquid biomarkers

    • Principal Investigator
      各務 博
    • Project Period (FY)
      2022 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Saitama Medical University
  •  肝微小環境の構造理解に基づく新たな代謝性肝疾患治療の確立

    • Principal Investigator
      本多 政夫
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 53:Organ-based internal medicine and related fields
    • Research Institution
      Kanazawa University
  •  Phosphoproteome analysis of the liver tissues with NAFLD/NASH and identification of therapeutic targets.

    • Principal Investigator
      HONDA Masao
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Kanazawa University
  •  Development of chemopreventive agents using Connectivity Map analysis

    • Principal Investigator
      TAKAYAMA Tetsuji
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokushima
  •  Identification of biomarkers to predict HCC development after successful treatment of viral hepatitis

    • Principal Investigator
      HONDA Masao
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Kanazawa University
  •  Establishment of molecular basis for improving the treatment efficacy of chronic hepatitis C and preventing the occurrence of hepatocellular carcinoma.

    • Principal Investigator
      HONDA Masao
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Kanazawa University
  •  Identification of host genes responsible for the treatment response of interferon therapy for the patients with chronic hepatitis C

    • Principal Investigator
      HONDA Masao
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Kanazawa University
  •  グラフィカル・モデルに基づく生命情報からの因果・関連性解析Principal Investigator

    • Principal Investigator
      堀本 勝久
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  Development of method for evaluating the consistency between network model in the cell and the molecular measured dataPrincipal Investigator

    • Principal Investigator
      HORIMOTO Katsuhisa
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      基礎ゲノム科学
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  Probabilistic Models of the Marginal Distribution of Gene Expression

    • Principal Investigator
      HORTON Paul
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      基礎ゲノム科学
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  グラフィカルモデルに基づく相互作用推定法の開発と適用Principal Investigator

    • Principal Investigator
      堀本 勝久
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  Developments of computational algebraic statistics

    • Principal Investigator
      TAKEMURA Akimichi
    • Project Period (FY)
      2006 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Statistical science
    • Research Institution
      The University of Tokyo
  •  グラフィカル・ガウシアン・モデルによる相互作用推定法の拡張とその適用Principal Investigator

    • Principal Investigator
      堀本 勝久
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  グラフィカル・モデリングに基づく相互作用推定法の確立と適用Principal Investigator

    • Principal Investigator
      堀本 勝久
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  グラフィカル・モデリングに基づく相互作用推定法の理論的研究と適用Principal Investigator

    • Principal Investigator
      堀本 勝久
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Macroscopic Genome Structure Comparison Based on Gene LocationsPrincipal Investigator

    • Principal Investigator
      HORIMOTO Katsuhisa
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      基礎ゲノム科学
    • Research Institution
      The University of Tokyo
  •  遺伝子配置情報に基づいた巨視的ゲノム構造比較法の確立と適用Principal Investigator

    • Principal Investigator
      堀本 勝久
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  遺伝子配置情報に基づくゲノム構造比較法の開発と適用Principal Investigator

    • Principal Investigator
      堀本 勝久
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      佐賀医科大学
  •  遺伝子配置情報に基づくゲノム構造比較法の開発Principal Investigator

    • Principal Investigator
      堀本 勝久
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      佐賀医科大学

All 2013 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book

  • [Book] Symbolic Computation in Biology, Math. Comput. Sci2009

    • Author(s)
      Anai, H., Horimoto, K. (eds)
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Book] Bioinformatics for Systems Biology: Second Edition, Introduction to Informatics(In Krawetz, S. (ed))2009

    • Author(s)
      Aburatani, S., Saito, S., Horimoto, K
    • Publisher
      Humana Press
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Book] Algebraic Biology, Lecture Notes in Computer Science2008

    • Author(s)
      Horimoto, K., Regensburger, G., Rosenkranz, M., Yoshida, H. (eds)
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Book] Algebraic Biology, Lecture Notes in Computer Science2007

    • Author(s)
      Anai, H., Horimoto, K., Kutsia, T. (eds)
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Book] Applied statistics for Network Biology: Methods in Systems Biology(F., Dehmer, M., Salvador, A. and Graber, A. (eds))

    • Author(s)
      Saito, S., Horimoto, K. : Network Screening
    • Publisher
      Wiley(in press)
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Journal Article] Gene expression profiling of hepatitis B-and hepatitis C-related hepatocellular carcinoma using graphical Gaussian modeling2013

    • Author(s)
      Ueda T, Honda M, Horimoto K, Aburatani S, Saito S, Yamashita T, Sakai Y, Nakamura M, Takatori H, Sunagozaka H, Kaneko S.
    • Journal Title

      Genomics

      Volume: Apr;101(4) Pages: 238-248

    • DOI

      10.1016/j.ygeno.2013.02.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23701098, KAKENHI-PROJECT-24390187, KAKENHI-PROJECT-24510285, KAKENHI-PROJECT-24701024
  • [Journal Article] Altered Hepatic Gene Expression Profiles Associated with Myocardial Ischemia.2010

    • Author(s)
      Ootsuji, H., Honda, M., Takamura, M., Usui, S., Okajima, M., D, Okada, H., Sakai, Y., Takamura, T., Horimoto, K., Kaneko, S
    • Journal Title

      Circ Cardiovasc Genet 3

      Pages: 68-77

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Journal Article] Period-Phase Map: Two-diemsional Selection of Circadian Rhythm-Related Genes.2009

    • Author(s)
      Morioka, R., Arita, M., Sakamoto, K., Kawaguchi, S., Tei, H., Horimoto, K
    • Journal Title

      IET Sys. Biol 3

      Pages: 487-495

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Journal Article] Detection of network structure changes by graphical chain modeling: a case study of hepatitis C virus-related hepatocellular carcinoma.2009

    • Author(s)
      Saito, S., Honda, M., Kaneko, S., Horimoto, K
    • Journal Title

      Proceedings of 48th IEEE Conference on Decision and Control

      Pages: 5624-5630

    • NAID

      120006655929

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Journal Article] Co-Expressed Gene Assessment Based on the Path Consistency Algorithm: Operon Detention in Escherichia coli. Proceedings of IEEE International Conference on Systems2009

    • Author(s)
      Saito, S., Horimoto, K
    • Journal Title

      Man and Cybernetics

      Pages: 4280-4286

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Journal Article] Differential miRNA expression between hepatitis B and hepatitis C leading disease progression to HCC.2009

    • Author(s)
      Ura, S., Honda, M., Yamashita, T., Ueda, T., Takatori, H., Nishino, R., Sunagozaka, H., Sakai, Y., Horimoto, K., Kaneko, S
    • Journal Title

      Hepatology 49

      Pages: 1098-1112

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Journal Article] Parameter Optimization in the network dynamics including unmeasured variables by the symbolic-numeric approach.2009

    • Author(s)
      Nakatsui, M., Horimoto, K
    • Journal Title

      Proceedings of the Third International Symposium on Optimization and Systems Biology (OSB'09)

      Pages: 245-253

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Journal Article] TRAIL inhibited the cyclic AMP responsible element mediated gene expression.2009

    • Author(s)
      Tokumoto, Y., Horimoto, K., Miyake, J
    • Journal Title

      Biochem. Biophys. Res. Commun 381

      Pages: 533-536

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Journal Article] Symbolic Computation in Biology2009

    • Author(s)
      Hirokazu Anai, Katsuhisa Horimoto (eds)
    • Journal Title

      Math.Comput.Sci. 2

      Pages: 399-556

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18200019
  • [Journal Article] Complementing Networks Using Observed Data.2009

    • Author(s)
      Akutsu, T., Tamura, T., Horimoto, K
    • Journal Title

      Lecture Notes in Artificial Intelligence 5809

      Pages: 126-140

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Journal Article] Analysis of network dynamics including hidden variables by symbolic-numeric approach.2008

    • Author(s)
      Tominaga, D., Tokumoto, Y., Nakatsui, M., Sun, F., Miyake, J., Horimoto, K
    • Journal Title

      Proceedings of the Second International Symposium on Optimization and Systems Biology (OSB'08)

      Pages: 242-248

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Journal Article] Phase Shifts of Circadian Transcripts in Rat Suprachiasmatic Nucleus.2008

    • Author(s)
      Morioka, R., Arita, M., Sakamoto, K., Kawaguchi, S., Tei, H., Horimoto, K
    • Journal Title

      Proceedings of the Second International Symposium on Optimization and Systems Biology (OSB'08)

      Pages: 109-114

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Journal Article] Identification of novel candidate tumour marker genes for intrahepatic cholangiocarcinoma.2008

    • Author(s)
      Nishino, R., Honda, M., Yamashita, T., Takatori, H., Minato, H., Zen, Y., Sasaki, M., Takamura, H., Horimoto, K., Ohta, T., Nakanuma, Y., Kaneko, S
    • Journal Title

      J. Hepatol 49

      Pages: 207-216

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Journal Article] An Algebraic-Numeric Algorithm for the Model Selection in Network Motifs in Escherichia coli.2008

    • Author(s)
      Nakatsui, M., Yoshida, H., Horimoto, K
    • Journal Title

      Proceedings of the Second International Symposium on Optimization and Systems Biology (OSB'08)

      Pages: 257-264

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Journal Article] Time Series Segmentation for Gene Regulatory Process with Time-Window-Extension Technique.2008

    • Author(s)
      Zhang, Z.Y., Horimoto, K., Liu, Z
    • Journal Title

      Proceedings of the Second International Symposium on Optimization and Systems Biology (OSB'08)

      Pages: 198-203

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Journal Article] Inference of Probabilities over a Stochastic IL-System by Quantifier Elimination.2008

    • Author(s)
      Yoshida, H., Horimoto, K., Anai, H
    • Journal Title

      Math. Comput. Sci 1

      Pages: 473-485

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Journal Article] Integer Programming-based Approach to Allocation of Reporter Genes for Cell Array Analysis.2008

    • Author(s)
      Hayashida, M., Sun, F., Aburatani, S., Horimoto, K., Akutsu, T
    • Journal Title

      Int. J. Bioinformatics Research and Applications 4

      Pages: 385-399

    • NAID

      110006402728

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Journal Article] Network evaluation from the consistency of the graph structure with the measured data.2008

    • Author(s)
      Saito, S., Aburatani, S., Horimoto, K
    • Journal Title

      BMC Sys. Biol 2

      Pages: 84-84

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Journal Article] Revealing Disease Related Interactions by Correlation Analysis.2008

    • Author(s)
      Wu, Z.K., Zhang, Z.Y., Zhang, L.W., Horimoto, K
    • Journal Title

      Proceedings of the Second International Symposium on Optimization and Systems Biology (OSB'08)

      Pages: 341-349

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Journal Article] An Algebraic-Numeric Algorithm for the Model Selection in Kinetic Networks.2007

    • Author(s)
      Yoshida, H., Nakagawa, K., Anai, H., Horimoto, K
    • Journal Title

      Proceedings of 10th CASC, LNCS(Springer, Heidelberg) 4770

      Pages: 433-447

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Journal Article] Integer Programming-based Approach to Allocation of Reporter Genes for Cell Array Analysis.2007

    • Author(s)
      Hayashida, M., Sun, F., Aburatani, S., Horimoto, K., Akutsu, T
    • Journal Title

      Proceedings of 10th OSB, Lecture Notes in Operation Research(Publishing Corporation)

      Pages: 288-301

    • NAID

      110006402728

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Journal Article] Inference of Protein-Protein Interactions by Using Co-evolutionary Information.2007

    • Author(s)
      Sato, T., Yamanishi, Y., Horimoto, K., Kanehisa, M., Toh, H
    • Journal Title

      Algebraic Biology, Lecture Notes in Computer Science(In Anai, H., Horimoto, K. and Kutsia, T. (eds)) 4545

      Pages: 322-333

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Journal Article] Derivation of rigorous conditions for high cell-type diversity by algebraic approach.2007

    • Author(s)
      Yoshida, H., Anai, H., Horimoto, K
    • Journal Title

      BioSystems 90

      Pages: 486-495

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Journal Article] Algebraic Biology.2007

    • Author(s)
      Hirokazu Anai, Katsuhisa Horimoto, Temure Kutsia. (eds)
    • Journal Title

      Lecture Notes in Computer Science Springer, Heidelberg

      Pages: 4545-4545

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18200019
  • [Journal Article] Exact parameter determination for Parkinson's disease diagnosis with PET using an algebraic approach.2007

    • Author(s)
      Yoshida, H., Nakagawa, K., Anai, H., Horimoto, K
    • Journal Title

      Algebraic Biology, Lecture Notes in Computer Science(In Anai, H., Horimoto, K., Kutsia, T. (eds)) 4545

      Pages: 110-124

    • Data Source
      KAKENHI-PROJECT-19201039
  • [Journal Article] Gene systems network inferred from expression profiles in hepatocellular carcinogenesis by graphical Gaussian model.2007

    • Author(s)
      Aburatani, S., Sun, F., Saito, S., Honda, M., Kaneko, S., Horimoto, K
    • Journal Title

      EURASIP J. Bioinfo. Systems Biol

      Pages: 47214-47214

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Journal Article] Gene systems network inferred from expression profiles in hepatocellular carcinogenesis by graphical Gaussian model.2007

    • Author(s)
      Sachiyo Aburatani, Fung Sun, Shigeru Saito, Masao Honda, Shuichi Kaneko, Katsuhisa Horimoto.
    • Journal Title

      EURASIP J.ioinfo. Systems Biol. 2007

      Pages: 47214-47214

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18200019
  • [Journal Article] Partial correlation coefficient between distance matrices as a new indicator of protein-protein interactions2006

    • Author(s)
      Sato, T., Yamanishi, Y, Horimoto, K., Kanehisa, M, Toh, H.
    • Journal Title

      Bioinformatics 22

      Pages: 2488-2492

    • Data Source
      KAKENHI-PROJECT-18016008
  • [Journal Article] A Graphical Chain Model for Inferring Regulatory System Networks from Gene Expression Profiles.2006

    • Author(s)
      Sachiyo Aburatani, Shigeru Saito, Hiroyuki Toh, Katsuhisa Horimoto.
    • Journal Title

      Statistical Methodology 3

      Pages: 17-28

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18200019
  • [Journal Article] Symbolic-numeric estimation of parameters in biochemical models by quantifier elimination.2006

    • Author(s)
      Anai, H., Orii, S., Horimoto, K
    • Journal Title

      J. Bioinfo. Comput. Biol. 4

      Pages: 1097-1117

    • Data Source
      KAKENHI-PROJECT-18016008
  • [Journal Article] A graphical chain model for inferring regulatory system networks from gene expression profiles.2006

    • Author(s)
      Aburatani, S., Saito, S., Toh, H., Horimoto, K.
    • Journal Title

      Statistical Methodology 3

      Pages: 17-28

    • Data Source
      KAKENHI-PROJECT-18016008
  • [Journal Article] Comparison between Profile-Profile Methods based on Hidden Markov Models and Multiple Alignments.2005

    • Author(s)
      Sato, M., Horimoto, K.
    • Journal Title

      Proceedings of the 9th World Multi-Conference on Systemics, Cybernetics and Informatics (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15310134
  • [Journal Article] Comparison between Profile-Profile Methods based on Hidden Markov Models and Multiple Alignments.2005

    • Author(s)
      Sato, M., Horimoto, K.
    • Journal Title

      Proceedings of the 9th World Multi-Conference on Systemics, Cybernetics and Informatics (印刷中)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15310134
  • [Journal Article] Parameter Optimization by Using Differential Elimination: a General Approach for Introducing Constraints into Objective Function.

    • Author(s)
      Nakatsui, M., Horimoto, K., Okamoto, M., Tokumoto, Y., Miyake, J
    • Journal Title

      BMC Sys. Biol (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Journal Article] Brute force meets Bruno force in parameter optimization: Introduction of novel constraints for parameter estimation by symbolic computation.

    • Author(s)
      Nakatsu, M., Horimoto, K., Lemaire, F., Urguplu, A., Sedoglavic, A., Boulier, F
    • Journal Title

      IET Sys. Biol (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Journal Article] Derivation of rigorous conditions for high cell-type diversity by algebraic approach.

    • Author(s)
      Yoshida, H., Anai, H., Horimoto, K
    • Journal Title

      BioSystems (in press)

    • Data Source
      KAKENHI-PROJECT-18016008
  • [Journal Article] Gene systems network inferred from expression profiles in hepatocellular carcinogenesis by graphical Gaussian model.

    • Author(s)
      5.Aburatani, S., Sun, F., Saito, S., Honda, M., Kaneko, S., Horimoto, K.
    • Journal Title

      EURASIP J. Bioinfo. Comput. Biol. (in press)

    • Data Source
      KAKENHI-PROJECT-18016008
  • [Presentation] Detection of network structure changes by graphical chain modeling: a case study of hepatitis C virus-related hepatocellular carcinoma.2009

    • Author(s)
      Saito, S., Honda, M., Kaneko, S., Horimoto, K
    • Organizer
      48th IEEE Conference on Decision and Control
    • Place of Presentation
      China
    • Year and Date
      2009-12-17
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Presentation] 代数的アプローチと遺伝的アルゴリズムの組み合わせによる計測不能変数を含むネットワークのパラメータ最適化2009

    • Author(s)
      中津井雅彦、堀本勝久
    • Organizer
      電子情報通信学会
    • Place of Presentation
      キャンパスイノベーションセンター(田町)
    • Year and Date
      2009-08-06
    • Data Source
      KAKENHI-PROJECT-20016028
  • [Presentation] Co-Expressed Gene Assessment Based on the Path Consistency Algorithm: Operon Detention in Escherichia coli.2009

    • Author(s)
      Saito, S., Horimoto, K
    • Organizer
      IEEE International Conference on Systems, Man and Cybernetics
    • Place of Presentation
      USA
    • Year and Date
      2009-10-11
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Presentation] Parameter optimization in network dynamics including unmeasured variables by the symbolic-numeric approach2009

    • Author(s)
      Nakatsui, M., Horimoto, K.
    • Organizer
      The Third International Symposium on Optimizationand Systems Biology
    • Place of Presentation
      Zhangjiajie, Hunan, China
    • Year and Date
      2009-09-20
    • Data Source
      KAKENHI-PROJECT-20016028
  • [Presentation] Parameter optimization in network dynamics including unmeasured variables by the symbolic-numeric approach2009

    • Author(s)
      Nakatsui, M., Horimoto, K.
    • Organizer
      The Third International Symposium on Optimization and Systems Biology
    • Place of Presentation
      Zhangjiajie, Hunan, China
    • Year and Date
      2009-09-20
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Presentation] Parameter Optimization in the network dynamics including unmeasured variables by the symbolic-numeric approach.2009

    • Author(s)
      Nakatsui, M., Horimoto, K
    • Organizer
      The Third International Symposium on Optimization and Systems Biology (OSB'09)
    • Place of Presentation
      China
    • Year and Date
      2009-09-20
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Presentation] Co-Expressed Gene Assessment Based on the Path Consistency Algorithm : Operon Detection in Escherichia coli2009

    • Author(s)
      Saito, S., Horimoto, K.
    • Organizer
      2009 IEEE International Conference on Systems, Man, and Cybernetics
    • Place of Presentation
      San Antonio, Texas, USA.
    • Year and Date
      2009-10-14
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Presentation] Trace of network structure changes by two approaches2009

    • Author(s)
      Horimoto, K.
    • Organizer
      ASI Symposium on Bioinformatics and Data Mining
    • Place of Presentation
      Hong Kong Baptist University
    • Year and Date
      2009-02-26
    • Data Source
      KAKENHI-PROJECT-20016028
  • [Presentation] Co-Expressed Gene Assessment Based on the Path Consistency Algorithm : Operon Detection in Escherichia coli2009

    • Author(s)
      Saito, S., Horimoto, K.
    • Organizer
      2009 IEEE International Conference on Systems, Man, and Cybernetics
    • Place of Presentation
      San Antonio, Texas, USA.
    • Year and Date
      2009-10-14
    • Data Source
      KAKENHI-PROJECT-20016028
  • [Presentation] 代数的アプローチと遺伝的アルゴリズムの組み合わせによる計測不能変数を含むネットワークのパラメータ最適化2009

    • Author(s)
      中津井雅彦、堀本勝久
    • Organizer
      電子情報通信学会
    • Place of Presentation
      キャンパスイノベーションセンター(田町)
    • Year and Date
      2009-08-06
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Presentation] Network Screening-Detection of Activated Pathways from the Data Measured in a Finite Condition2009

    • Author(s)
      Horimoto, K.
    • Organizer
      Computational Systems Biology Workshop
    • Place of Presentation
      Shanghai University
    • Year and Date
      2009-09-19
    • Data Source
      KAKENHI-PROJECT-20016028
  • [Presentation] Detection of network structure changes by graphical chain modeling:a case study of hepatitis C virus-related hepatocellular carcinoma2009

    • Author(s)
      Saito, S., Horimoto, K.
    • Organizer
      Joint 48th IEEE Conference on Decision and Control and 28th Chinese Control Conference
    • Place of Presentation
      Shanghai, China.
    • Year and Date
      2009-12-17
    • Data Source
      KAKENHI-PROJECT-20016028
  • [Presentation] 遺伝子発現プロファイルによるネットワーク構造評価2009

    • Author(s)
      齊藤秀、堀本勝久
    • Organizer
      電子情報通信学会
    • Place of Presentation
      キャンパスイノベーションセンター(田町)
    • Year and Date
      2009-08-06
    • Data Source
      KAKENHI-PROJECT-20016028
  • [Presentation] "Network Screening"-Detection of Activated Pathways from the Data Measured in a Finite Condition2009

    • Author(s)
      Horimoto, K.
    • Organizer
      Computational Systems Biology Workshop
    • Place of Presentation
      Shanghai University
    • Year and Date
      2009-09-19
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Presentation] Detection of network structure changes by graphical chain modeling : a case study of hepatitis C virus-related hepatocellular carcinoma2009

    • Author(s)
      Saito, S., Horimoto, K.
    • Organizer
      Joint 48th IEEE Conference on Decision and Control and 28th Chinese Control Conference
    • Place of Presentation
      Shanghai, China.
    • Year and Date
      2009-12-17
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Presentation] 遺伝子発現プロファイルによるネットワーク構造評価2009

    • Author(s)
      齊藤秀、堀本勝久
    • Organizer
      電子情報通信学会
    • Place of Presentation
      キャンパスイノベーションセンター(田町)
    • Year and Date
      2009-08-06
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Presentation] 進展型疾患のネットワークモデル2008

    • Author(s)
      堀本勝久
    • Organizer
      医療と情報技術の連携イノベーショフォーラム
    • Place of Presentation
      東京大学本郷キャンパス工学部
    • Year and Date
      2008-12-02
    • Data Source
      KAKENHI-PROJECT-20016028
  • [Presentation] An Algebraic-Numeric Algorithm for the Model Selection in Network Motifs in Escherichia coli.2008

    • Author(s)
      Nakatsui, M., Yoshida, H., Horimoto, K
    • Organizer
      The Second International Symposium on Optimization and Systems Biology (OSB'08)
    • Place of Presentation
      China
    • Year and Date
      2008-10-18
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Presentation] Phase Shifts of Circadian Transcripts in Rat Suprachiasmatic Nucleus.2008

    • Author(s)
      Morioka, R., Arita, M., Sakamoto, K., Kawaguchi, S., Tei, H., Horimoto, K
    • Organizer
      The Second International Symposium on Optimization and Systems Biology (OSB'08)
    • Place of Presentation
      China
    • Year and Date
      2008-10-18
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Presentation] 2つアプローチによる時間発展するネットワーク構造変化解析2008

    • Author(s)
      堀本勝久
    • Organizer
      BMB2008(第31回日本分子生物学会年会・第81回日本生化学会大会
    • Place of Presentation
      神戸ポートピアホテル
    • Year and Date
      2008-12-12
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Presentation] Time Series Segmentation for Gene Regulatory Process with Time-Window-Extension Technique.2008

    • Author(s)
      Zhang, Z.Y., Horimoto, K., Liu, Z
    • Organizer
      The Second International Symposium on Optimization and Systems Biology (OSB'08)
    • Place of Presentation
      China
    • Year and Date
      2008-10-18
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Presentation] 2つアプローチによる時間発展するネットワーク構造変化解析2008

    • Author(s)
      堀本勝久
    • Organizer
      BMB2008(第31回日本分子生物学会年会・第81回日本生化学会大会
    • Place of Presentation
      神戸ポートピアホテル
    • Year and Date
      2008-12-12
    • Data Source
      KAKENHI-PROJECT-20016028
  • [Presentation] Analysis of network dynamics including hidden variables by symbolic-numeric approach.2008

    • Author(s)
      Tominaga, D., Tokumoto, Y., Nakatsui, M., Sun, F., Miyake, J., Horimoto, K
    • Organizer
      The Second International Symposium on Optimization and Systems Biology (OSB'08)
    • Place of Presentation
      China
    • Year and Date
      2008-10-18
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Presentation] 進展型疾患のネットワークモデル2008

    • Author(s)
      堀本勝久
    • Organizer
      医療と情報技術の連携イノベーショフォーラム
    • Place of Presentation
      東京大学本郷キャンパス工学部
    • Year and Date
      2008-12-02
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Presentation] Revealing Disease Related Interactions by Correlation Analysis.2008

    • Author(s)
      Wu, Z.K., Zhang, Z.Y., Zhang, L.W., Horimoto, K
    • Organizer
      The Second International Symposium on Optimization and Systems Biology (OSB'08)
    • Place of Presentation
      China
    • Year and Date
      2008-10-18
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Presentation] Network Inference and Evaluation Based on Graphical Model.2008

    • Author(s)
      Horimoto. K.
    • Organizer
      Seminar on Computational Systems Biology
    • Place of Presentation
      Shanghai University
    • Year and Date
      2008-08-13
    • Data Source
      KAKENHI-PROJECT-20016028
  • [Presentation] Network Inference and Evaluation Based on Graphical Model2008

    • Author(s)
      Horimoto, K.
    • Organizer
      Seminar on Computational Systems Biology
    • Place of Presentation
      Shanghai University
    • Year and Date
      2008-08-13
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Presentation] Consistency of causal graph with measured data2007

    • Author(s)
      Horimoto, K.
    • Organizer
      International Conference on Multiple Decision Theory, Statistical Inference and Applications
    • Place of Presentation
      Taiwan Science Academy
    • Data Source
      KAKENHI-PROJECT-18016008
  • [Presentation] Design of Analysis Toolsfor Network Inference and Evaluation2007

    • Author(s)
      Horimoto, K.
    • Organizer
      Systems Biology Workshop
    • Place of Presentation
      英国大使館
    • Data Source
      KAKENHI-PROJECT-18016008
  • [Presentation] Dynamical analysis of biological networks by using reporter gene expreslsions in transfected cell microarray2007

    • Author(s)
      Horimoto, K.
    • Organizer
      DMHF2007
    • Place of Presentation
      九州大学
    • Data Source
      KAKENHI-PROJECT-18016008
  • [Presentation] 代数生物学-記号計算による生命現象解析2007

    • Author(s)
      堀本 勝久
    • Organizer
      Innovative Mathematical Approaches for Systems Biology:System Identification, Analysis, Control and Design
    • Place of Presentation
      九州大学産業技術数理研究センター
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Presentation] Consistency of causal graph with measured data2007

    • Author(s)
      Horimoto, K.
    • Organizer
      International Conference on Multiple Decision Theory, Statistical Inference and Applications
    • Place of Presentation
      Taiwan Science Academy
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Presentation] Exact parameter determination for Parkinson's disease diagnosis with PET using an algebraic approach2007

    • Author(s)
      Yoshida, H., Nakagawa, K., Anai, H., Horimoto, K
    • Organizer
      Algebraic Biology 2007
    • Place of Presentation
      Austria
    • Year and Date
      2007-07-02
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Presentation] 創薬・副作用予測にむけた生命分子ネットワーク解析法の開発2007

    • Author(s)
      堀本 勝久
    • Organizer
      日本バイオインフォマティクス学会, JSBi合同研究会
    • Place of Presentation
      東京大学医科学研究所
    • Data Source
      KAKENHI-PROJECT-18016008
  • [Presentation] 創薬・副作用予測にむけた生命分子ネットワーク解析法の開発2007

    • Author(s)
      堀本 勝久
    • Organizer
      日本バイオインフォマティクス学会, JSBi合同研究会
    • Place of Presentation
      東京大学医科学研究所
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Presentation] An Algebraic-Numeric Algorithm for the Model Selection in Kinetic Networks.2007

    • Author(s)
      Yoshida, H., Nakagawa, K., Anai, H., Horimoto, K
    • Organizer
      10th CASC
    • Place of Presentation
      Germany
    • Year and Date
      2007-09-16
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Presentation] Inference of Protein-Protein Interactions by Using Co-evolutionary Information2007

    • Author(s)
      Sato, T., Yamanishi, Y., Horimoto, K., Kanehisa, M., Toh, H
    • Organizer
      Algebraic Biology 2007
    • Place of Presentation
      Austria
    • Year and Date
      2007-07-02
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Presentation] Dynamical analysis of biological networks by using reporter gene expressions in transfected cell microarray2007

    • Author(s)
      Horimoto, K.
    • Organizer
      DMHF2007
    • Place of Presentation
      九州大学
    • Data Source
      KAKENHI-PROJECT-19201039
  • [Presentation] 代数生物学一記号計算による生命現象解析2007

    • Author(s)
      堀本 勝久
    • Organizer
      Innovative Mathematical Approaches for Systems Biology:System Identification, Analysis, Control and Design
    • Place of Presentation
      九州大学産業技術数理研究センター
    • Data Source
      KAKENHI-PROJECT-18016008
  • [Presentation] Design of Analysis Tools for Network Inference and Evaluation2007

    • Author(s)
      Horimoto, K.
    • Organizer
      Systems Biology Workshop
    • Place of Presentation
      英国大使館
    • Data Source
      KAKENHI-PROJECT-19201039
  • 1.  HONDA Masao (00272980)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 1 results
  • 2.  藤 博幸 (70192656)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 3 results
  • 3.  ABURATANI Sachiyo (10361627)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 8 results
  • 4.  ANAI Hirokazu (20417520)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 10 results
  • 5.  YOSHIDA Hiroshi (60401262)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 10 results
  • 6.  OOSUGI Hidefumi (80350289)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  KAMIYA Hidehiko (50300687)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  SAI Shidou (30186910)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 9.  HIBI Takayuki (80181113)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  SAKAI Yoshio (80401925)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  TAKEMURA Akimichi (10171670)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  AOKI Satoshi (90332618)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  KURIKI Satoshi (90195545)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  SAKATA Toshio (20117352)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  SHIBUYA MASAAKI (20146723)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  NIKI Naoto (10000209)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  HOSHINO Nobuaki (00313627)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  HONDA Toshio (30261754)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 19.  TOMINAGA Daisuke (20357578)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 20.  HORTON Paul (00371071)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  FUKUCHI Satoshi (70360336)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  YAMASHITA Taro (90377432)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  SHIMAKAMI Tetsuro (50436820)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  TAKAYAMA Tetsuji (10284994)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  武藤 倫弘 (30392335)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  岡本 耕一 (60531374)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  六車 直樹 (90325283)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  鍵和田 晴美 (40443204)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  土居 信英 (50327673)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  岡田 光 (50788916)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  各務 博 (30418686)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  解良 恭一 (40400783)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  砂子阪 肇
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 34.  鷹取 元
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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