Shiina Isamu 椎名勇

… Alternative Names

SHIINA Isamu 椎名勇

SHIMA Isamu 椎名勇

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Researcher Number	40246690
Other IDs
External Links
Affiliation (Current)	2025: 東京理科大学, 理学部第一部応用化学科, 教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 東京理科大学, 理学部第一部応用化学科, 教授 2017 – 2021: 東京理科大学, 理学部第一部応用化学科, 教授 2010 – 2014: 東京理科大学, 理学部, 教授 2007 – 2008: Tokyo University of Science, 理学部, 教授 2005 – 2006: 東京理科大学, 理学部, 助教授 … More 2003: Tokyo University of Science, Faculty of Science, Associate Professor, 理学部, 助教授 1999 – 2002: 東京理科大学, 理学部, 講師 1998: 総合研究所, 講師 1997 – 1998: 東京理科大学, 総合研究所, 講師 1993 – 1996: 東京理科大学, 総合研究所, 助手 Less
Review Section/Research Field	Principal Investigator Organic chemistry / Organic chemistry / Science and Engineering / Science and Engineering / Synthetic chemistry Except Principal Investigator Basic Section 52040:Radiological sciences-related / 物質変換 / Organic chemistry / Synthetic chemistry / Clinical oncology
Keywords	Principal Investigator 不斉全合成 / 有機合成化学 / MNBA / 不斉アルドール反応 / 有機化学 / ラクトン化 / アルドール反応 / タキソール / アルコール / カルボン酸 … More / 動的速度論光学分割 / 速度論的光学分割 / 不斉合成 / 2-メチル-6-ニトロ安息香酸無水物 / 中員環ラクトン / オクタラクチン / 立体選択的合成法 / 高速縮合反応 / 2-エピボトチノリド / ボトチノリド / ヨウ化サマリウム / 抗がん剤 / 全合成 / 抗癌剤 / タキソ-ル / エステル / マクロライド / 混合酸無水物 / 安息香酸無水物 / ルイス酸触媒 / エステル合成 / Mixed-anhydride / Lactonization / Asymmetric Aldol Reaction / Asymmetric Total Synthesis / 8-Membered Ring Lactone / Cytotoxic Activity / Octalactins / アンチ-ヒドロキシメチルユニット / 二価スズのトリフラート / 光学活性ジアミン / 鎖状ポリオキシ化合物 / オクタラクチンA / 高速ラクトン化 / アンチユニット / 8員環ラクトン / MNBAラクトン化 / 置換安息香酸無水物 / 立体選択的脱官能基化 / 非天然型類縁体 / 抗腫瘍活性 / 不斉配位子 / 軸不斉 / 求核性塩基 / 光学分割 / 求核性塩基触媒 / 不斉触媒 / ディールス・アルダー反応 / マイケル反応 / ビニリデンアセタート / エノール化 / 2-アリールプロピオン酸 / ビニリデンアシラート / 縮合反応 / 光学活性カルボン酸 / 光学活性アルコール / 不斉エステル化 / 脱水縮合 / ラソフォキシフェン / ドロキシフェン / イドキシフェン / 疑似ホルモン型治療薬 / ワンポット連結反応 / 不飽和型求核剤 / 芳香族求電子剤 / 4, 4-ジアリールー1-ブテン類 / 四塩化ハフニウム / アニソール / シンナミルシラン / 芳香族アルデヒド / シリルエーテル / Friedel-Crafis反応 / 3成分連結反応 / ワッカー型酸化 / 第四級不斉炭素 / 消炎漢方薬 / イリドイド / バーゲリニンF / クライゼン転移 / アスタコラクチン / 天然薬理活性ラクトン / アンチマイシン / 置換安息香酸無水物法 / 9員環ジラクトン / 分子内カップリング / 7員環ラクトン / 三環性分子 / 5-エピメリリアニン / 還元的カップリング / ジチアンカップリング / ペンタエリトリトール / ペルオキシデメチルメリリアニン / リュウマチ / セスキテルペン / トウシキミ / メリリアニン / 中員環 / ラクトン / 2-メチル6-ニトロ安息香酸無水物 / 中員環ラクトン形成反応 / 農薬 / 植物生長阻害活性 / 9員環ラクトン / α,β-エポキシケトン / 類縁体合成 / ビスアルドール反応 / オキセリン / CDOP / DPTC / フェニルイソセリン / 19-ヒドロキシタキソール / α,α-ジクロロエチルケトン / 8員環環化反応 / α-モノクロロエチルケトン / アルキル化 / 1,1-ジクロロエチルリチウム / タキソール類縁体 / タキサン系化合物 / バッカチンIII / 8員環状化合物 / D-パントラクトン / L-セリン / 分子内ピナコール反応 / 分子内アルドール反応 / マイケル付加反応 / 炭素八員環 / シロキ酸 / 酸水物 / マクロラクトン / 触媒 / ルイス酸 … More Except Principal Investigator 抗炎症剤 / 分子標的創薬 / p53 / 放射線防護剤 / 連続的反応 / プロトン酸 / トリチル塩 / チオグリコシド / 糖鎖合成 / グリコシル化反応 / ルイス酸 / 放射線併用抗腫瘍薬 / 抗炎症作用 / 正常組織防護 / 細胞死 / α-glycoside / bromo sugar / glycosyl phosphite / glycosyl phosphonium salt / O-linked mucin glycosyl amino acid / one-pot sequential glycosylation / β-selective mannosylation / thioformimidate / 枝分かれ型糖鎖 / F1α抗原 / シアロシド合成 / 糖質化学 / α-グリコシド / グリコシルホスフィナイト糖 / ワンポット連続的グリコシル化 / β-選択的マンノシル化学反応 / αグリコシド / ブロモ糖 / グリコシルホスフィナイト / グリコシルホスホニウム塩 / ムチン型糖鎖 / ワンポット連続的反応 / β選択的マンノシル化反応 / チオホルムイミデート / N-(Ethylthio)phthalimide / Trifluoromethanesulfonic acid / Trityl tetrakis(pentafluorophenyl)borate / Thioglycoside / One-pot sequential syntheses / Trisaccharides / Glycosylation / ワンポット合成 / チオカルバモイル基 / 2-デオキシピラノシド / N-ブロモコハク酸イミド / N-ヨ-ドコハク酸イミド / N-ヨードコハク酸イミド / ワンポット3糖合成反応 / Samarium(II)Iodide / 19-Hydroxy Taxol / 18-Hydroxy Taxol / 8-Membered Ring Enone / Aldol Reaction / D-Pantolactone / Anti-tumor Agent / Taxol / 分子内アルドール型反応 / ワッカー型酸化反応 / 二塩化パラジウム / α、β-エポキシケトン / 連続的アルドール反応 / 低原子価チタン / 二価スズのトリフラート / 19-ヒドロキシタキソール / 18-ヒドロキシタキソール / Knoevenagel反応 / ホウ素エノラート / 銅-亜鉛合金 / ヨウ化ナトリウム / アルドール反応 / 8員環化合物 / サマリウムエノラート / ビスアルドール / 分子内Knoevenagel反応 / D-パントラクトン / 8員環状化合物 / タキソール類縁体 / 不斉全合成 / タキソール / bening synthesis / aqueous reaction / scandium trifluoromethanesulfonate / Lewis asic / polymer-supported catalysts / aldol reaction / hafnium (IV) triflate / Friedel-Crafts acylation / アミノケトン / キノリン / Fries転位 / Friedel-Craftsアシル化 / スカンジウムトリフラート / ランタノイドトルフラート / 高分子触媒 / マイクロカプセル / Friedel-Craftsアシル化反応 / ハフニウム化合物 / 界面活性剤 / ランタノイド / 情報システム / 分子薬理学 / 分子標的薬 / がん治療 Less

Development of Combination Radiation Therapy Drugs to Improve Cancer Control Rates by Regulating DNA Damage Response Molecules
- Principal Investigator
  
  森田明典
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  The University of Tokushima
Development of radioprotectors that selectively protect normal tissues
- Principal Investigator
  
  MORITA Akinori
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  The University of Tokushima
Development of asymmetric dehydration condensation reaction with kinetic or dynamic kinetic resolution of enantiomers and effective synthesis of non-natural amino acidsPrincipal Investigator
- Principal Investigator
  
  Shiina Isamu
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Organic chemistry
- Research Institution
  Tokyo University of Science
ビニリデンジアセタート類の触媒活性化を利用した新規合成反応の開発Principal Investigator
- Principal Investigator
  
  椎名勇
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Tokyo University of Science
Development of C2-Symmetric Pyridine N-Oxides as New Nucleophilic Catalysts and Application for the Asymmetric SynthesisPrincipal Investigator
- Principal Investigator
  
  SHIINA Isamu
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Organic chemistry
- Research Institution
  Tokyo University of Science
Discovery of innovative molecular targeted drugs based on Cancer Cell Informatics
- Principal Investigator
  
  YAMORI Takao
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Clinical oncology
- Research Institution
  Japanese Foundation For Cancer Research
Design of the Nonenzymatic Effective Dehydration Condensation Reaction and its Application to the Synthesis of Biologically Active MoleculesPrincipal Investigator
- Principal Investigator
  
  SHIINA Isamu
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Synthetic chemistry
- Research Institution
  Tokyo University of Science
芳香族求電子剤ならびに2種の不飽和型求核剤を用いるワンポット3成分連結反応の開発Principal Investigator
- Principal Investigator
  
  椎名勇
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Tokyo University of Science
高速縮合反応を基盤技術とする薬理活性天然中員環化合物の不斉全合成Principal Investigator
- Principal Investigator
  
  椎名勇
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Tokyo University of Science
新規中員環形成法を基盤技術とする植物成長阻害活性物質ボトチノリド類の不斉合成研究Principal Investigator
- Principal Investigator
  
  椎名勇
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Tokyo University of Science
Asymmetric Total Synthesis of Medium-sized Lactones Using Rapid CyclizationPrincipal Investigator
- Principal Investigator
  
  SHIINA Isamu
- Project Period (FY)
  2005 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Organic chemistry
- Research Institution
  Tokyo University of Science
タキソール類縁抗がん活性化合物の有効な合成法の確立Principal Investigator
- Principal Investigator
  
  椎名勇
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Organic chemistry
- Research Institution
  Tokyo University of Science
Study for stereoselective synthesis of oligosaccharides by new glycosylation methods
- Principal Investigator
  
  MUKAIYAMA Teruaki
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  物質変換
- Research Institution
  The Kitasato Institute
  Tokyo University of Science
Asymmetric Total Synthesis of Octalactins A, B and Their AnaloguesPrincipal Investigator
- Principal Investigator
  
  SHIINA Isamu
- Project Period (FY)
  2000 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Organic chemistry
- Research Institution
  Tokyo University of Science
抗がん剤タキソールおよびその類縁体の効率的不斉全合成Principal Investigator
- Principal Investigator
  
  椎名勇
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Organic chemistry
- Research Institution
  Tokyo University of Science
Asymmetric Synthesis of Anti-tumor Agent Taxol and Its Analogues
- Principal Investigator
  
  TERUAKI Mukaiyama
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Organic chemistry
- Research Institution
  Tokyo University of Science
A New and Stereoselective Glycosylation and Synthesis of Origosuccaride
- Principal Investigator
  
  MUKAIYAMA Teruaki
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  物質変換
- Research Institution
  Science University of Tokyo
抗癌剤タキソールならびにタキソール類縁体の化学的不斉全合成Principal Investigator
- Principal Investigator
  
  椎名勇
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Organic chemistry
- Research Institution
  Tokyo University of Science
抗腫瘍活性化合物タキソ-ルの不斉全合成Principal Investigator
- Principal Investigator
  
  椎名勇
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Organic chemistry
- Research Institution
  Tokyo University of Science
Development of Synthetic Reactions Using New Types of Lewix Acid Catalysts
- Principal Investigator
  
  KOBAYASHI Shu
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Synthetic chemistry
- Research Institution
  The University of Tokyo
  Tokyo University of Science
ルイス酸触媒を用いる効率的縮合反応の開発Principal Investigator
- Principal Investigator
  
  椎名勇
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Organic chemistry
- Research Institution
  Tokyo University of Science
金属触媒を用いる新しい脱水縮合反応の開発研究Principal Investigator
- Principal Investigator
  
  椎名勇
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Organic chemistry
- Research Institution
  Tokyo University of Science
ルイス酸触媒を用いる効率的エステル生成法および中・大環状ラクトン合成法の開発研究Principal Investigator
- Principal Investigator
  
  椎名勇
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Organic chemistry
- Research Institution
  Tokyo University of Science

[Book] エステル・アミドって何？　ラクトンって何？　－理科大発！ MNBAを用いた世界最速合成法の開発－2019
- Author(s)
  椎名　勇
- Total Pages
  6
- Publisher
  理大科学フォーラム
- Data Source
  KAKENHI-PROJECT-17H03024
[Book] 有機合成法実験ハンドブック2015
- Author(s)
  椎名　勇他
- Total Pages
  1000
- Publisher
  丸善
- Data Source
  KAKENHI-PROJECT-22350044
[Book] 「医薬品の不純物を有効成分に変化させる方法の開発（純度は2倍、効果は3～4倍！）」科研費NEWS 2012年度VOL.42013
- Author(s)
  椎名　勇
- Total Pages
  2
- Publisher
  文部科学省・独立行政法人日本学術振興会
- Data Source
  KAKENHI-PROJECT-22350044
[Book] Natural Lactones and Lactams: Synthesis, Occurrence and Biological Activity2013
- Author(s)
  Isamu Shiina, Kenya Nakata
- Total Pages
  376
- Publisher
  Wiley-VCH Verlag GmbH & Co. KGaA
- Data Source
  KAKENHI-PROJECT-23655045
[Book] Natural Lactones and Lactams: Synthesis, Occurrence and Biological Activity2013
- Author(s)
  Isamu Shiina, Kenya Nakata
- Total Pages
  376
- Publisher
  Wiley-VCH Verlag GmbH & Co. KGaA
- Data Source
  KAKENHI-PROJECT-22350044
[Book] トップドラッグから学ぶ創薬化学2012
- Author(s)
  椎名　勇
- Total Pages
  199
- Publisher
  東京化学同人
- Data Source
  KAKENHI-PROJECT-23655045
[Book] 「天然物合成で活躍した反応」(No.98)椎名ラクトン化2011
- Author(s)
  椎名勇
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-22350044
[Book] Various Synthetic Methods Using Aromatic Carboxylic Anhydrides2011
- Author(s)
  Isamu Shiina
- Publisher
  TCI MAIL Int. Ed
- Data Source
  KAKENHI-PROJECT-23655045
[Book] 「トップドラッグから学ぶ創薬化学」(No.2)アルドール反応2011
- Author(s)
  椎名勇
- Publisher
  東京化学同人
- Data Source
  KAKENHI-PUBLICLY-23105544
[Book] 天然物合成で活躍した反応2011
- Author(s)
  椎名　勇
- Total Pages
  209
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-23655045
[Book] 「使える!有機合成反応実践ガイド241」(No.127)置換安息香酸無水物を用いる脱水縮合反応2010
- Author(s)
  椎名勇
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-22350044
[Book] New Acid Catalysis for Modern Organic Chemistry2008
- Author(s)
  Isamu SHIINA
- Publisher
  Wiley-VCH
- Data Source
  KAKENHI-PROJECT-17350023
[Book] New Acid Catalysis for Modern Organic Chemistry(2)2008
- Author(s)
  Isamu SHIINA and Hiroki HUKUI
- Publisher
  Wiley-VCH
- Data Source
  KAKENHI-PROJECT-17350023
[Book] Electronic Encyclopedia of Reagents for Organic Synthesis(10)2008
- Author(s)
  Isamu SHIINA
- Publisher
  2-Methyl-6-nitrobenzoic Anhydride (MNBA)
- Data Source
  KAKENHI-PROJECT-17350023
[Book] New Acid Catalysis for Modern Organic Chemistry2008
- Author(s)
  Isamu SHIINA
- Publisher
  Wiley-VCH
- Data Source
  KAKENHI-PROJECT-19020065
[Journal Article] A Novel RNA Synthesis Inhibitor, STK160830, Has Negligible DNA-Intercalating Activity for Triggering A p53 Response, and Can Inhibit p53-Dependent Apoptosis2021
- Author(s)
  Morita Akinori、Ochi Shintaro、Satoh Hidetoshi、Ujita Shohei、Matsushita Yosuke、Tada Kasumi、Toyoda Mihiro、Nishiyama Yuichi、Mizuno Kosuke、Deguchi Yuichi、Suzuki Keiji、Tanaka Yoshimasa、Ueda Hiroshi、Inaba Toshiya、Hosoi Yoshio、Aoki Shin
- Journal Title
  
  Life
  
  Volume: 11 Issue: 10 Pages: 1087-1087
- DOI
  10.3390/life11101087
- NAID
  120007164908
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03604, KAKENHI-PROJECT-21H02948, KAKENHI-PROJECT-20K05712, KAKENHI-PROJECT-21K07644
[Journal Article] Evaluation of sodium orthovanadate as a radioprotective agent under total-body irradiation and partial-body irradiation conditions in mice2021
- Author(s)
  Nishiyama Yuichi、Morita Akinori、Wang Bing、Sakai Takuma、Ramadhani Dwi、Satoh Hidetoshi、Tanaka Kaoru、Sasatani Megumi、Ochi Shintaro、Tominaga Masahide、Ikushima Hitoshi、Ueno Junji、Nenoi Mitsuru、Aoki Shin
- Journal Title
  
  International Journal of Radiation Biology
  
  Volume: 97 Issue: 9 Pages: 1241-1251
- DOI
  10.1080/09553002.2021.1941377
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03604, KAKENHI-PROJECT-20K05712, KAKENHI-PROJECT-21K07644
[Journal Article] Kinetic Resolution of Racemic 2‐Hydroxyarylketones by Asymmetric Esterification: Investigation of the Influence of the Co‐Base on the Selectivity2020
- Author(s)
  Murata Takatsugu、Futami Kengo、Ishikawa Ryo、Ono Keisuke、Nakata Kenya、Shiina Isamu
- Journal Title
  
  Asian Journal of Organic Chemistry
  
  Volume: 9 Issue: 2 Pages: 202-205
- DOI
  10.1002/ajoc.201900702
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03024
[Journal Article] Total Synthesis of the Antitumor Depsipeptide FE399 and its S-Benzyl Derivative: A Macrolactamization Approach2020
- Author(s)
  Tonoi Takayuki、Ikeda Miyuki、Sato Teruyuki、Inohana Takehiko、Kawahara Ryo、Murata Takatsugu、Shiina Isamu
- Journal Title
  
  ChemRxiv
  
  Volume: 4 Pages: 1-16
- DOI
  10.26434/chemrxiv.12017796
- Open Access
- Data Source
  KAKENHI-PROJECT-17H03024
[Journal Article] Total Synthesis and Antimicrobial Evaluation of 23-Demethyleushearilide and Extensive Antimicrobial Evaluation of All Synthetic Stereoisomers of (16Z,20E)-Eushearilide and (16E,20E)-Eushearilide2019
- Author(s)
  Tonoi Takayuki、Inohana Takehiko、Sato Teruyuki、Noda Yuuki、Ikeda Miyuki、Akutsu Miku、Murata Takatsugu、Maekawa Yutaro、Tanaka Anna、Seki Rio、Ohkusu Misako、Kamei Katsuhiko、Ishiwada Naruhiko、Shiina Isamu
- Journal Title
  
  Molecules
  
  Volume: 24 Issue: 19 Pages: 3437-3437
- DOI
  10.3390/molecules24193437
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03024
[Journal Article] Silylative Kinetic Resolution of Racemic 2,2‐Dialkyl 5‐ and 6‐Membered Cyclic Benzylic Alcohol Derivatives Catalyzed by Chiral Guanidine, (R)‐N‐Methylbenzoguanidine2019
- Author(s)
  Yoshimatsu Shuhei、Nakata Kenya
- Journal Title
  
  Advanced Synthesis & Catalysis
  
  Volume: 361 Issue: 20 Pages: 4679-4684
- DOI
  10.1002/adsc.201900761
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03024
[Journal Article] Novel Ridaifen-B Structure Analog Induces Apoptosis and Autophagy Depending on Pyrrolidine Side Chain2019
- Author(s)
  Iwasawa Takumi、Shinomiya Takahisa、Ota Nozomi、Shibata Natsumi、Nakata Kenya、Shiina Isamu、Nagahara Yukitoshi
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 42 Issue: 3 Pages: 401-410
- DOI
  10.1248/bpb.b18-00643
- NAID
  130007605974
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2019-03-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03024
[Journal Article] N822K- or V560G-mutated KIT activation preferentially occurs in lipid rafts of the Golgi apparatus in leukemia cells.2019
- Author(s)
  Obata Y, Hara Y, Shiina I, Murata T, Tasaki Y, Suzuki K, Ito K, Tsugawa S, Yamawaki K, Takahashi T, Okamoto K, Nishida T, Abe R.
- Journal Title
  
  Cell Commun. Signal.
  
  Volume: 4 Issue: 1 Pages: 114-114
- DOI
  10.1186/s12964-019-0426-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07208, KAKENHI-PROJECT-19H03722, KAKENHI-PROJECT-17H03024
[Journal Article] Diastereo-/Enantioselective Diels-Alder Synthesis of 14β-Hydroxysteroid Scaffolds: A Combined Experimental and DFT Study2019
- Author(s)
  Shiina Isamu、Miesch Michel、Peter Clovis、Geoffroy Philippe、Murata Takatsugu、Tonoi Takayuki
- Journal Title
  
  HETEROCYCLES
  
  Volume: 99 Issue: 2 Pages: 1251-1251
- DOI
  10.3987/com-18-s(f)99
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03024
[Journal Article] Ridaifen-F conjugated with cell-penetrating peptides inhibits intracellular proteasome activities and induces drug-resistant cell death.2018
- Author(s)
  Tanaka, M., Zhu, Y., Shionyu, M., Ota, N., Shibata, N., Watanabe, C., Mizusawa, A., Sasaki, R., Mizukami, T., Shiina, I., Hasegawa, M.
- Journal Title
  
  European Journal of Medicinal Chemistry
  
  Volume: 146 Pages: 636-650
- DOI
  10.1016/j.ejmech.2018.01.045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08329, KAKENHI-PROJECT-15K00411, KAKENHI-PROJECT-17H03024
[Journal Article] Asymmetric Total Synthesis of (+)-Coprophilin2018
- Author(s)
  Shiina Isamu、Umezaki Yuma、Murata Takatsugu、Suzuki Kyohei、Tonoi Takayuki
- Journal Title
  
  Synthesis
  
  Volume: 50 Issue: 06 Pages: 1301-1306
- DOI
  10.1055/s-0036-1591866
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03024
[Journal Article] Kinetic Resolution of Racemic 2-Hydroxyamides Using a Diphenylacetyl Component as an Acyl Source and a Chiral Acyl-Transfer Catalyst2018
- Author(s)
  Murata Takatsugu、Kawanishi Tatsuya、Sekiguchi Akihiro、Ishikawa Ryo、Ono Keisuke、Nakata Kenya、Shiina Isamu
- Journal Title
  
  Molecules
  
  Volume: 23 Issue: 8 Pages: 2003-2021
- DOI
  10.3390/molecules23082003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03024
[Journal Article] Total Synthesis of Violaceoid A and (-)- and (+)-Violaceoid B2018
- Author(s)
  Murata Takatsugu、Kuboki Teppei、Ishikawa Ryo、Saito Takahiro、Taguchi Shotaro、Takeuchi Kazuma、Hatano Emiko、Shimonaka Motoyuki、Shiina Isamu
- Journal Title
  
  Journal of Natural Products
  
  Volume: 81 Issue: 11 Pages: 2364-2370
- DOI
  10.1021/acs.jnatprod.8b00215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03024
[Journal Article] Oncogenic Kit signalling on the Golgi is suppressed by blocking secretory trafficking with M-COPA in gastrointestinal stromal tumours.2018
- Author(s)
  Obata Y, Horikawa K, Shiina I, Takahashi T, Murata T, Tasaki Y, Suzuki K, Yonekura K, Esumi H, Nishida T, Abe R
- Journal Title
  
  Cancer Lett.
  
  Volume: 415 Pages: 1-10
- DOI
  10.1016/j.canlet.2017.11.032
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05419, KAKENHI-PROJECT-15K06843, KAKENHI-PROJECT-16K14619, KAKENHI-PROJECT-16K18427, KAKENHI-PROJECT-17H03024
[Journal Article] Anti-proliferative effect of ridaifen-B on hepatoma cells2018
- Author(s)
  Hasegawa Go、Akatsuka Kotomi、Hiruma Keita、Suda Kayako、Yokoe Yumiko、Mizusawa Akihito、Ota Nozomi、Shibata Natsumi、Tsuchiya Kaho、Hayashi Moyuru、Shiina Isamu、Shimonaka Motoyuki
- Journal Title
  
  Biomedical Reports
  
  Volume: 9 Pages: 175-180
- DOI
  10.3892/br.2018.1112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03024
[Journal Article] Total Synthesis and Antimicrobial Activities of All Stereoisomers of (16Z,20E)-Eushearilide and (16E,20E)-Eushearilide2018
- Author(s)
  Tonoi Takayuki、Inohana Takehiko、Sato Teruyuki、Yoshida Tomoki、Shiina Isamu
- Journal Title
  
  The Journal of Organic Chemistry
  
  Volume: 83 Issue: 15 Pages: 7886-7899
- DOI
  10.1021/acs.joc.8b00774
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03024
[Journal Article] Targeting the Golgi apparatus to overcome acquired resistance of non-small cell lung cancer cells to EGFR tyrosine kinase inhibitors2017
- Author(s)
  Yoshimi Ohashi, Mutsumi Okamura, Ryohei Katayama, Siyang Fang, Saki Tsutsui, Akinobu Akatsuka, Mingde Shan, Hyeong-Wook Choi, Naoya Fujita, Kentaro Yoshimatsu, Isamu Shiina, Takao Yamori, and Shingo Dan
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 2 Pages: 1641-1655
- DOI
  10.18632/oncotarget.22895
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-17H06324, KAKENHI-PROJECT-16H05105, KAKENHI-PROJECT-17K07230, KAKENHI-PROJECT-17H03024
[Journal Article] Total Synthesis of (3R,16E,20E,23R)-(-)-Eushearilide and Structural Determination of Naturally Occurring Eushearilide2015
- Author(s)
  T. Tonoi, R. Kawahara, Y. Yoshinaga, T. Inohana, K. Fujimori, I. Shiina
- Journal Title
  
  Tetrahedron Letters
  
  Volume: 56 Issue: 11 Pages: 1356-1359
- DOI
  10.1016/j.tetlet.2015.01.181
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-22350044
[Journal Article] Development of Kinetic Resolution of Racemic Alcohols and Carboxylic Acids Accompanied with Dehydration Condensation2014
- Author(s)
  椎名　勇, 中田健也
- Journal Title
  
  Journal of Synthetic Organic Chemistry, Japan
  
  Volume: 72 Issue: 8 Pages: 919-928
- DOI
  10.5059/yukigoseikyokaishi.72.919
- NAID
  130004691492
- ISSN
  0037-9980, 1883-6526
- Language
  Japanese
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-22350044
[Journal Article] A Novel Tamoxifen Derivative, Ridaifen-F, Is a Nonpeptidic Small-molecule Proteasome Inhibitor2014
- Author(s)
  Makoto Hasegawa, Yukari Yasuda, Makoto Tanaka, Kenya Nakata, Eri Umeda, Yanwen Wang, Chihiro Watanabe, Shoko Uetake,Tatsuki Kunoh, Masafumi Shionyu, Ryuzo Sasaki, Isamu Shiina, Tamio Mizukami
- Journal Title
  
  European Journal of Medicinal Chemistry
  
  Volume: 71 Pages: 290-305
- DOI
  10.1016/j.ejmech.2013.11.009
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-22350044, KAKENHI-PROJECT-24510317
[Journal Article] M-COPA, a Golgi Disruptor, Inhibits Cell Surface Expression of MET Protein and Exhibits Antitumor Activity Against MET-addicted Cancers2014
- Author(s)
  Yoshimi Ohashi, Mutsumi Okamura, Asaka Hirosawa, Akinobu Akatsuka, Isamu Shiina, Kentarou Yoshimatsu, Takao Yamori, Shingo Dan
- Journal Title
  
  European Journal of Cancer
  
  Volume: 50, Supplement 6 Pages: 185-186
- DOI
  10.1016/s0959-8049(14)70700-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22350044
[Journal Article] Asymmetric Mukaiyama Aldol Reactions Using Chiral Diamine-Coordinated Sn(II) Triflate: Development and Application to Natural Product Synthesis2014
- Author(s)
  I. Shiina
- Journal Title
  
  The Chemical Record
  
  Volume: 14 Issue: 1 Pages: 144-183
- DOI
  10.1002/tcr.201300022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22350044, KAKENHI-PROJECT-23655045
[Journal Article] An Adventurous Synthetic Journey with MNBA from Its Reaction Chemistry to the Total Synthesis of Natural Products2014
- Author(s)
  I. Shiina
- Journal Title
  
  Bull. Chem. Soc. Jpn.
  
  Volume: 87 Issue: 2 Pages: 196-233
- DOI
  10.1246/bcsj.20130216
- NAID
  130004153271
- ISSN
  0009-2673, 1348-0634
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22350044
[Journal Article] Total Synthesis of the Proposed Structure of Astakolactin2014
- Author(s)
  T. Tonoi, K. Mameda, M. Fujishiro, Y. Yoshinaga, I. Shiina
- Journal Title
  
  Beilstein Journal of Organic Chemistry
  
  Volume: 10 Pages: 2421-2427
- DOI
  10.3762/bjoc.10.252
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-22350044
[Journal Article] 脱水縮合を伴う速度論的光学分割反応の開発2014
- Author(s)
  中田健也、椎名　勇
- Journal Title
  
  有機合成化学協会誌
  
  Volume: 72
- NAID
  130004691492
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23655045
[Journal Article] Novel tamoxifen derivative Ridaifen-B induces Bcl-2 independent autophagy without estrogen receptor involvement.2013
- Author(s)
  Takeyoshi M, Sakemoto S, Shiina I, Nakata K, Fujimori K, Wang Y, Umeda E, Watanabe C, Uetake S, Yamori T, Dan S, Yoshimi Y, Shinomiya T, Ikekita M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092
[Journal Article] Search for Novel Anti-tumor Agents from Ridaifens Using JFCR39, a Panel of Human Cancer Cell Lines.2013
- Author(s)
  Guo WZ, Wang Y, Umeda E, Shiina I, Dan S, Yamori T.
- Journal Title
  
  Biol Pharm Bull.
  
  Volume: in press
- NAID
  130003361461
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092
[Journal Article] Kinetic Resolution of Racemic α-Hydroxyphosphonates by Asymmetric Esterification Using Achiral Carboxylic Acids with Pivalic Anhydride and a Chiral Acyl-Transfer Catalyst2013
- Author(s)
  I. Shiina, K. Ono, T. Nakahara
- Journal Title
  
  Chemical Communications
  
  Volume: 49 Issue: 91 Pages: 10700-10702
- DOI
  10.1039/c3cc44293d
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22350044
[Journal Article] Novel tamoxifen derivative Ridaifen-B induces Bcl-2 independent autophagy without estrogen receptor involvement2013
- Author(s)
  Nagahara Y, Takeyoshi M, Sakemoto S, Shiina I, Nakata K, Fujimori K, Wang Y, Umeda E, Watanabe C, Uetake S, Yamori T, Dan S, Yoshimi Y, Shinomiya T, Ikekita M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 435(4) Issue: 4 Pages: 657-63
- DOI
  10.1016/j.bbrc.2013.05.040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092
[Journal Article] Kinetic Resolution of Racemic α-Hydroxyphosphonates by Asymmetric Esterification Using Achiral Carboxylic Acids with Pivalic Anhydride and a Chiral Acyl-Transfer Catalyst2013
- Author(s)
  Isamu Shiina, Keisuke Ono, Takayoshi Nakahara
- Journal Title
  
  Chemical Communications
  
  Volume: 49 Pages: 10700-10702
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23655045
[Journal Article] Total synthesis of AMF-26, an antitumor agent for inhibition of the Golgi system, targeting ADP-ribosylation factor 12013
- Author(s)
  Shiina I, Umezaki Y, Ohashi Y, Yamazaki Y, Dan S, Yamori T
- Journal Title
  
  J Med Chem
  
  Volume: 56(1) Issue: 1 Pages: 150-159
- DOI
  10.1021/jm301695c
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092, KAKENHI-PROJECT-23655045
[Journal Article] Fine Structures in Vibrational Circular Dichroism Spectra of Chiral Molecules with Rotatable Hydroxyl Groups and Their Application in the Analysis of Local Intermolecular Interactions2013
- Author(s)
  K. Konno, I. Shiina, H. Yui
- Journal Title
  
  Journal of Molecular Structure
  
  Volume: 1035 Pages: 260-266
- DOI
  10.1016/j.molstruc.2012.11.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22350044, KAKENHI-PROJECT-22685009, KAKENHI-PROJECT-23655045
[Journal Article] Search for Novel Anti-tumor Agents from Ridaifens Using JFCR39, a Panel of Human Cancer Cell Lines2013
- Author(s)
  Guo WZ, Wang Y, Umeda E, Shiina I, Dan S, Yamori T
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 36 Issue: 6 Pages: 1008-1016
- DOI
  10.1248/bpb.b13-00129
- NAID
  130003361461
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092
[Journal Article] Development of a gene expression database and related analysis programs for evaluation of anticancer compounds.2013
- Author(s)
  Ushijima M, Mashima T, Tomida A, Dan S, Saito S, Furuno A, Tsukahara S, Seimiya H, Yamori T, Matsuura M.
- Journal Title
  
  Cancer Sci.
  
  Volume: 104(3) Issue: 3 Pages: 360-368
- DOI
  10.1111/cas.12071
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092, KAKENHI-PROJECT-22300341, KAKENHI-PROJECT-23501319, KAKENHI-PROJECT-23701067, KAKENHI-PROJECT-24240042, KAKENHI-PROJECT-24650626, KAKENHI-PROJECT-24650639, KAKENHI-PROJECT-25290060, KAKENHI-PROJECT-25290061, KAKENHI-PROJECT-221S0001, KAKENHI-PUBLICLY-23117527
[Journal Article] Kinetic Resolution of Racemic 2-Hydroxy-γ-butyrolactones by Asymmetric Esterification Using Diphenylacetic Acid with Pivalic Anhydride and a Chiral Acyl-Transfer Catalyst2013
- Author(s)
  K. Nakata, K. Gotoh, K. Ono, K. Futami, I. Shiina
- Journal Title
  
  Organic Letters
  
  Volume: 15 Issue: 6 Pages: 1170-1173
- DOI
  10.1021/ol303453j
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22350044, KAKENHI-PROJECT-23655045
[Journal Article] An Enantiodivergent Synthesis of (+)- and (-)-Centrolobines via the Asymmetric Esterification Catalyzed by (R)-(+)-N-Methylbenzoguanidine ((R)-NMBG)2013
- Author(s)
  Kenya Nakata, Tatsuya Tokumaru, Hidetoshi Iwamoto, Yutaka Nishigaichi, Isamu Shiina
- Journal Title
  
  Asian Journal of Organic Chemistry
  
  Volume: 2 Pages: 920-922
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23655045
[Journal Article] Kinetic Resolution of Racemic 2-Hydroxy-・-butyrolactones by Asymmetric Esterification Using Diphenylacetic Acid with Pivalic Anhydride and a Chiral Acyl-Transfer Catalyst2013
- Author(s)
  Kenya Nakata, Kouya Gotoh, Keisuke Ono, Kengo Futami, Isamu Shiina
- Journal Title
  
  Organic Letters
  
  Volume: 15 Pages: 1170-1173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23655045
[Journal Article] Kinetic Resolution of Racemic Secondary Benzylic Alcohols by the Enantioselective Esterification Using 3-PCA with Chiral Acyl-transfer Catalysts2012
- Author(s)
  I. Shiina, K. Nakata, K. Ono, T. Mukaiyama
- Journal Title
  
  Helvetica Chimica Acta
  
  Volume: 95 Issue: 10 Pages: 1891-1911
- DOI
  10.1002/hlca.201200434
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23655045
[Journal Article] MNBA-Mediated β-Lactone Formation: Mechanistic Studies and Application for the Asymmetric Total Synthesis of Tetrahydrolipstatin2012
- Author(s)
  I. Shiina, Y. Umezaki, N. Kuroda, T. Iizumi, S. Nagai, T. Katoh
- Journal Title
  
  J. Org. Chem
  
  Volume: 77 Issue: 11 Pages: 4885-4901
- DOI
  10.1021/jo300139r
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22350044
[Journal Article] A New Method for Production of Chiral 2-Aryloxypropanoic Acids Using Effective Kinetic Resolution of Racemic 2-Aryloxycarboxylic Acids2012
- Author(s)
  A. Tengeiji, K. Nakata, K. Ono, I. Shiina
- Journal Title
  
  Heterocycles
  
  Volume: 86 Issue: 2 Pages: 1227-1252
- DOI
  10.3987/com-12-s(n)79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22350044, KAKENHI-PROJECT-23655045, KAKENHI-PUBLICLY-23105544
[Journal Article] A New Method for Production of Chiral 2-Aryl-2-fluorpropanoic Acids Using an Effective Kinetic Resolution of Racemic 2-Aryl-2-fluoropropanic Acids2012
- Author(s)
  A. Tengeiji, I. Shiina
- Journal Title
  
  Molecules
  
  Volume: 17 Issue: 6 Pages: 7356-7378
- DOI
  10.3390/molecules17067356
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22350044, KAKENHI-PROJECT-23655045, KAKENHI-PUBLICLY-23105544
[Journal Article] Benzylic Alcohols by the Enantioselective Esterification Using 3-PCA with Chiral Acyl-transfer Catalysts2012
- Author(s)
  Isamu Shiina, Kenya Nakata, Keisuke Ono, Teruaki Mukaiyama
- Journal Title
  
  Helvetica Chimica Acta
  
  Volume: 95 Pages: 1891-1911
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23655045
[Journal Article] Non-Enzymatic Dynamic Kinetic Resolution of Racemic α-Arylalkanoic Acids: an Advanced Asymmetric Synthesis of Chiral Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)2012
- Author(s)
  I. Shiina, K. Ono, K. Nakata
- Journal Title
  
  Catalysis - Science & Technology
  
  Volume: 2 Issue: 11 Pages: 2200-2205
- DOI
  10.1039/c2cy20329d
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22350044, KAKENHI-PUBLICLY-23105544
[Journal Article] Ridaifen-G Induced Caspase-independent Atypical Cell Death2011
- Author(s)
  Anlifeire. A.; Hatori. H.; Morita, A.; Shiina, I.; Nakata, K.; Tosaki, Y.; Wang, Y.; Ikekita, M.; Li, G.
- Journal Title
  
  Chin.J.Cell Biol.
  
  Volume: 33 Pages: 635-644
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22350044
[Journal Article] A Convenient Method for the Kinetic Resolution of Racemic 2-Hydroxyalkanoates Using Diphenylacetic Anhydride (DPHAA) and a Chiral Acyl-Transfer Catalyst2011
- Author(s)
  Nakata, K.; Sekiguchi, A.; Shiina, I.
- Journal Title
  
  Tetrahedron: Asymmetry
  
  Volume: 22 Pages: 1610-1619
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23655045
[Journal Article] (R)-(+)-N-Methylbenzoguanidine ((R)-NMBG) Catalyzed Kinetic Resolution of Racemic Secondary Benzylic Alcohols with Free Carboxylic Acids by Asymmetric Esterification2011
- Author(s)
  Nakata, K.; Shiina, I.
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 9 Pages: 7092-7096
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23655045
[Journal Article] (R)-(+)-N-Methylbenzoguanidine ((R)-NMBG) Catalyzed Kinetic Resolution of Racemic Secondary Benzylic Alcohols with Free Carboxylic Acids by Asymmetric2011
- Author(s)
  Nakata, K.; Shiina, I.
- Journal Title
  
  Org.Biomol.Chem.
  
  Volume: 9 Pages: 7092-7096
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23105544
[Journal Article] Kinetic Resolution of the Racemic 1-(Aryloxazol-2-yl)carbinols with Achiral Carboxylic Acids by Asymmetric Esterification : A New Method for the Preparation of Chiral 1, 2-Amino Alcohols2011
- Author(s)
  Kenya Nakata, Keisuke Ono, Isamu Shiina
- Journal Title
  
  Heterocycles
  
  Volume: 82 Pages: 1171-1180
- NAID
  40018702708
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23655045
[Journal Article] Kinetic Resolution of the Racemic I-Heteroarylcarbinols by the Asymmetric Esterification Using Diphenylacetic Acid with Pivalic Anhydride and a Chiral Acyl-Transfer Catalyst2011
- Author(s)
  Shiina, I.: Ono, K.; Nakata, K.
- Journal Title
  
  Chem.Lett.
  
  Volume: 40 Pages: 147-149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22350044
[Journal Article] A Convenient Method for the Kinetic Resolution of Racemic 2-Hydroxyalkanoates Using Diphenylacetic Anhydride (DPHAA) and Chiral Acyl-transfer Catalyst2011
- Author(s)
  Kenya Nakata, Akihiro Sekiguchi, Isamu Shiina
- Journal Title
  
  Tetrahedron : Asymmetry
  
  Volume: 22 Pages: 1610-1619
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23655045
[Journal Article] Kinetic Resolution of the Racemic I-(Aryloxazol-2-yl) carbinols with Achiral Carboxylic Acids by Asymmetric Esterification : A New Method for the Preparation of Chiral 1,2-Amino Alcohols2011
- Author(s)
  Nakata, K.; Ono, K.; Shiina, I.
- Journal Title
  
  Heterocycles
  
  Volume: 82 Pages: 1171-1180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22350044
[Journal Article] Kinetic Resolution of the Racemic 1-(Aryloxazol-2-yl)carbinols with Achiral Carboxylic Acids by Asymmetric Esterification: A New Method for the Preparation of Chiral 1,2-Amino Alcohols2011
- Author(s)
  Nakata, K.; Ono, K.; Shiina, I.
- Journal Title
  
  Heterocycles
  
  Volume: 82 Pages: 1171-1180
- NAID
  40018702708
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23655045
[Journal Article] A Convenient Method for the Kinetic Resolution of Racemic 2-Hydroxyalkanoates Using Diphenylacetic Anhydride (DPHAA) and a Chiral2011
- Author(s)
  Nakata, K.; Sekiguchi, A.; Shiina, I.
- Journal Title
  
  Tetrahedron : Asymmetry
  
  Volume: 22 Pages: 1610-1619
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23105544
[Journal Article] (R)-(+)-N-Methylbenzoguanidine ((R)-NMBG) Catalyzed Kinetic Resolution of Racemic Secondary Benzylic Alcohols with Free Carboxylic Acids by Asymmetric Esterification2011
- Author(s)
  Kenya Nakata, Isamu Shiina
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 9 Pages: 7092-7096
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23655045
[Journal Article] Kinetic Resolution of the Racemic 1-Heteroarylcarbinols by the Asymmetric Esterification Using Diphenylacetic Acid with Pivalic Anhydride and a Chiral Acyl-Transfer Catalyst2011
- Author(s)
  Shiina, I.; Ono, K.; Nakata, K.
- Journal Title
  
  Chem. Lett.
  
  Volume: 40 Pages: 147-149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23655045
[Journal Article] Various Synthetic Method Using Aromatic Carboxylic Anhydrides2011
- Author(s)
  Shiina, I.
- Journal Title
  
  TCI MAIL
  
  Volume: 144 Pages: 2-15
- Data Source
  KAKENHI-PROJECT-23655045
[Journal Article] An Effective Kinetic Resolution of Racemic Secondary Benzylic Alcohols Using 3-Pyridinecarboxylic Anhydride and a Chiral Acyl-Transfer Catalyst in the Absence of Tertiary Amine2010
- Author(s)
  Nakata, K.; Shiina, I.
- Journal Title
  
  Heterocycles
  
  Volume: 80 Pages: 169-175
- NAID
  40016900094
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22350044
[Journal Article] Kinetic Resolution of Racemic a-Arylalkanoic Acids with Achiral Alcohols via the Asymmetric Esterification Using Carboxylic Anhydrides and Acyl-Transfer Catalysts2010
- Author(s)
  Shiina, I.; Nakata, K.; Ono, K.; Onda, Y.; Itagaki, M.
- Journal Title
  
  J.Am.Chem.Soc.
  
  Volume: 132 Pages: 11629-11641
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22350044
[Journal Article] Kinetic Resolution of the Racemic 2-Hydroxyalkanoates Using the Enantioselective Mixed-Anhydride Method with Pivalic Anhydride and a Chiral Acyl-Transfer Catalyst2010
- Author(s)
  Shiina, I.; Nakata, K.; Ono, K.; Sugimoto, M.; Sekiguchi, A.
- Journal Title
  
  Chem.Eur.J.
  
  Volume: 16 Pages: 167-172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22350044
[Journal Article] Total Synthesis and the Confirmation of the Revised Structures of Botcinins A and B2009
- Author(s)
  Hiroki FUKUI, Keisuke TSUJI, Yuma UMEZAKI, andIsamu SHIINA
- Journal Title
  
  Heterocycles 79
  
  Pages: 403-410
- Data Source
  KAKENHI-PROJECT-17350023
[Journal Article] Chemistry and Structural Determination of Botcinolides2009
- Author(s)
  Botcinins, and Botcinic Acids, Isamu SHIINA and Hiroki FUKUI
- Journal Title
  
  Chemical Communications
  
  Pages: 385-400
- Data Source
  KAKENHI-PROJECT-17350023
[Journal Article] Synthesis and Pharmacological Evaluation of the Novel pseudo-Symmetrical Tamoxifen Derivatives as Anti-tumor Agents2008
- Author(s)
  Isamu SHIINA
- Journal Title
  
  Biochemical Pharmacology 75
  
  Pages: 1014-1026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19020065
[Journal Article] Total Synthesis of 2-Hydroxytetracosanolide and 2-Hydroxy-24-oxooctacosanolide Using anEffective Lactonization2008
- Author(s)
  Isamu SHIINA, Akane SASAKI, Takaaki KIKUCHI, and Hiroki FUKUI
- Journal Title
  
  Chemistry-an Asian Journal 3
  
  Pages: 462-472
- Data Source
  KAKENHI-PROJECT-17350023
[Journal Article] Total Synthesis of 2-Hydroxytetracosanolide and 2-Hydroxy-24-oxooctacosanolide Using an Effective Lactonization2008
- Author(s)
  椎名勇
- Journal Title
  
  Chemistry-an Asian Journal 3
  
  Pages: 462-472
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18032074
[Journal Article] Synthesis and Pharmacological Evaluation of the Novel pseudo-Symmetrical Tamoxifen Derivatives as Anti-tumor Agents2008
- Author(s)
  椎名勇
- Journal Title
  
  Biochemical Pharmacology 75
  
  Pages: 1014-1026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17350023
[Journal Article] Total Synthesis of 2-Hydroxytetracosanolide and 2-Hydroxy-24-oxooctacosanolide Using an Effective Lactonization2008
- Author(s)
  Isamu SHIINA
- Journal Title
  
  Chemistry-an Asian Journal 2
  
  Pages: 462-472
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17350023
[Journal Article] Total Synthesis of 2-Hydroxytetracosanolide and 2-Hydroxy-24-oxooctacosanolide Using an Effective Lactonization2008
- Author(s)
  椎名勇
- Journal Title
  
  Chemistry-an Asian Journal 3
  
  Pages: 462-472
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17350023
[Journal Article] Asymmetric Total Synthesis of Botcinins C, D, and F2008
- Author(s)
  Hiroki FUKUI and Isamu SHIINA
- Journal Title
  
  Organic Letters 10
  
  Pages: 3153-3156
- Data Source
  KAKENHI-PROJECT-17350023
[Journal Article] Synthesis and Pharmacological Evaluation of the Novel pseudo-Symmetrical Tamoxifen Derivatives as Anti-tumor Agents2008
- Author(s)
  椎名勇
- Journal Title
  
  Biochemical Pharmacology 75
  
  Pages: 1014-1026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19020065
[Journal Article] 4-(Dimethylamino)pyridine N-oxide (DMAPO) : an Effective Nucleophilic Catalyst in the Peptide Coupling Reaction Using 2-Methyl-6-nitrabenzoic Anhydride2008
- Author(s)
  椎名勇
- Journal Title
  
  Chemistry-an Asian Journal 3
  
  Pages: 454-461
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18032074
[Journal Article] Asymmetric Total Synthesis of Botcinic Acid and Its Derivatives : Synthetic Revision ofthe Structure of Botcinolides2008
- Author(s)
  Hiroki FUKUI, Seiichi HITOMI, Ryo-suke SUZUKI, TatsuhikoIKEDA, Yuma UMEZAKI, Keisuke TSUJI, andIsamu SHIINA
- Journal Title
  
  Tetrahedron Letters 49
  
  Pages: 6514-6517
- Data Source
  KAKENHI-PROJECT-17350023
[Journal Article] Synthesis of Lactones Using Substituted Benzoic Anhydride as a Coupling Reagent2007
- Author(s)
  Isamu SHIINA, Hiroki FUKUI, and Akane SASAKI
- Journal Title
  
  Nature Protocols 2
  
  Pages: 2312-2317
- Data Source
  KAKENHI-PROJECT-17350023
[Journal Article] Synthesis of Lactones Using Substituted Benzoic Anhydride as a Coupling Reagent2007
- Author(s)
  Isamu SHIINA
- Journal Title
  
  Nature Protocols 2(印刷中)
- Data Source
  KAKENHI-PROJECT-18032074
[Journal Article] Synthesis of Lactones Using Substituted Benzoic Anhydride as a Coupling Reagent2007
- Author(s)
  椎名勇
- Journal Title
  
  Nature Protocols 2
  
  Pages: 2312-2317
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18032074
[Journal Article] Total Synthesis of Natural 8- and 9- Membered Lactones : Recent Advancements inMedium-Sized Ring Formation2007
- Author(s)
  Isamu SHIINA
- Journal Title
  
  Chemical Reviews 107
  
  Pages: 239-273
- Data Source
  KAKENHI-PROJECT-17350023
[Journal Article] Total Synthesis of Natural 8- and 9-Membered Lactones : Recent Advancement in Medium-sized Ring Formation2007
- Author(s)
  Isamu SHIINA
- Journal Title
  
  Chemical Reviews 107
  
  Pages: 239-273
- Data Source
  KAKENHI-PROJECT-18032074
[Journal Article] Synthesis of the New pseudo-Symmetrical Tamoxifen Derivatives and Their Anti-tumor Activity2007
- Author(s)
  椎名勇
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters 17
  
  Pages: 2421-2424
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17350023
[Journal Article] Total Synthesis of Natural 8- and 9-Membered Lactones : Recent Advancement in Medium-sized Ring Formation2007
- Author(s)
  Isamu SHIINA
- Journal Title
  
  Chemical Reviews 107
  
  Pages: 239-273
- Data Source
  KAKENHI-PROJECT-17350023
[Journal Article] An Expeditious Synthesis of Tamoxifen, A Representative SERM (Selective Estrogen Receptor Modulator), via the Three-Component Coupling Reaction among Aromatic Aldehyde, Cinnamyltrimethylsilane avd β-Chlorophenetole2007
- Author(s)
  椎名勇
- Journal Title
  
  Bioorganic & Medicinal Chemistry 15
  
  Pages: 7599-7617
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19020065
[Journal Article] Synthesis of Lactones Using Substituted Benzoic Anhydride as a Coupling Reagent2007
- Author(s)
  椎名勇
- Journal Title
  
  Nature Protocols 2
  
  Pages: 2312-2317
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17350023
[Journal Article] The First Asymmetric Esterification of Free Carboxylic Acids with Racemic Alcohols Using Benzoic Anhydrides and Tetramisole Derivatives: An Application to the Kinetic Resolution of Secondary Benzylic Alcohols2007
- Author(s)
  椎名勇
- Journal Title
  
  Tetrahedron Letters 48
  
  Pages: 8314-8317
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17350023
[Journal Article] Synthesis of the New pseudo-Symmetrical Tamoxifen Derivatives and Their Anti-tumor Activity2007
- Author(s)
  Isamu SHIINA
- Journal Title
  
  Bioorganic ＆ Medicinal Chemistry Letters 17
  
  Pages: 2421-2424
- Data Source
  KAKENHI-PROJECT-18032074
[Journal Article] An Expeditious Synthesis of Tamoxifen, A Representative SERM (Selective Estrogen Receptor Modulator), via the Three-Component Coupling Reaction among Aromatic Aldehyde, Cinnamyltrimethylsilane and β-Chlorophenetole2007
- Author(s)
  椎名勇
- Journal Title
  
  Bioorganic & Medicinal Chemistry 15
  
  Pages: 7599-7617
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17350023
[Journal Article] Synthesis of the New pseudo-Symmetrical Tamoxifen Derivatives and Their Anti-tumor Activity2007
- Author(s)
  椎名勇
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters 17
  
  Pages: 2421-2424
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19020065
[Journal Article] Synthesis of Lactones Using Substituted Benzoic Anhydride as a Coupling Reagent2007
- Author(s)
  Isamu SHIINA
- Journal Title
  
  Nature Protocols 2(印刷中)
- Data Source
  KAKENHI-PROJECT-17350023
[Journal Article] Synthesis of the New pseudo-Symmetrical Tamoxifen Derivatives and Their Anti-tumor Activity2007
- Author(s)
  Isamu SHIINA
- Journal Title
  
  Bioorganic ＆ Medicinal Chemistry Letters 17
  
  Pages: 2421-2424
- Data Source
  KAKENHI-PROJECT-17350023
[Journal Article] The First Total Synthesis of (-) and (+)-2-Hydroxy-24-oxooctacosanolide Using an Effective Lactonization2006
- Author(s)
  Isamu SHIINA
- Journal Title
  
  Organic Letters 8
  
  Pages: 4955-4958
- Data Source
  KAKENHI-PROJECT-17350023
[Journal Article] The First Total Synthesis of(-)and(+)-2-Hydroxy-24-oxooctacosanolide Using anEffective Lactonization2006
- Author(s)
  Isamu SHIINA, Takaaki KIKUCHI, and Akane SASAKI
- Journal Title
  
  Organic Letters 8
  
  Pages: 4955-4958
- Data Source
  KAKENHI-PROJECT-17350023
[Journal Article] Stereoselective Total Synthesis of the Proposed Structure of 2-Epibotcinolide2006
- Author(s)
  Isamu SHIINA
- Journal Title
  
  Organic Letters 8
  
  Pages: 5279-5282
- Data Source
  KAKENHI-PROJECT-17350023
[Journal Article] Computational Study on the Reaction Mechanism of the Key Thermal [4+4] Cycloaddition Reaction in the Biosynthesis of Epoxytwinol A2006
- Author(s)
  Isamu SHIINA
- Journal Title
  
  Organic Letters 8
  
  Pages: 1041-1044
- Data Source
  KAKENHI-PROJECT-18032074
[Journal Article] 1-Methoxy-2-methylseleno-1-(trimethylsiloxy)propene2006
- Author(s)
  Isamu SHIINA
- Journal Title
  
  Electronic Encyclopedia of Reagents for Organic Synthesis 8
  
  Pages: 1-12
- Data Source
  KAKENHI-PROJECT-17350023
[Journal Article] Synthesis of (9E)-Isoambrettolide, a Macrocyclic Musk Compound, Using the Effective Lactonization Promoted by Symmetric Benzoic Anhydrides with Basic Catalysts2006
- Author(s)
  Isamu SHIINA
- Journal Title
  
  Tetrahedron 62
  
  Pages: 7934-7939
- Data Source
  KAKENHI-PROJECT-17350023
[Journal Article] 置換安息香酸無水物を用いる実用的縮合反応2006
- Author(s)
  椎名勇
- Journal Title
  
  ケミカルエンジニアリング 51
  
  Pages: 702-706
- Data Source
  KAKENHI-PROJECT-18032074
[Journal Article] Computational Study on the Reaction Mechanism of the Key Thermal [4+4] Cycloaddition Reaction in the Biosynthesis of Epoxytwinol A2006
- Author(s)
  Isamu SHIINA
- Journal Title
  
  Organic Letters 8
  
  Pages: 1041-1044
- Data Source
  KAKENHI-PROJECT-17350023
[Journal Article] Stereoselective Total Synthesis of the Proposed Structure of 2-Epibotcinolide2006
- Author(s)
  Isamu SHIINA, Yu-ji TAKASUNA, Ryo-suke SUZUKI,Hiromi OSHIUMI, Yuri KOMIYAMA, SeiichiHITOMI, and Hiroki FUKUI
- Journal Title
  
  Organic Letters 8
  
  Pages: 5279-5282
- Data Source
  KAKENHI-PROJECT-17350023
[Journal Article] Stereoselective Total Synthesis of the Proposed Structure of 2-Epibotcinolide2006
- Author(s)
  Isamu SHIINA
- Journal Title
  
  Organic Letters 8
  
  Pages: 5279-5282
- Data Source
  KAKENHI-PROJECT-18032074
[Journal Article] Computational Study on the Reaction Mechanism of the Key Thermal [4+4] Cycloaddition Reaction in the Biosynthesis of Epoxytwinol A2006
- Author(s)
  Isamu SHIINA
- Journal Title
  
  Organic Letters 8(印刷中)
- Data Source
  KAKENHI-PROJECT-17350023
[Journal Article] The First Total Synthesis of (-) and (+)-2-Hydroxy-24-oxooctacosanolide Using an Effective Lactonization2006
- Author(s)
  Isamu SHIINA
- Journal Title
  
  Organic Letters 8
  
  Pages: 4955-4958
- Data Source
  KAKENHI-PROJECT-18032074
[Journal Article] 1-Methoxy-2-methylseleno-1-(trimethylsiloxy)propene2006
- Author(s)
  Isamu SHIINA
- Journal Title
  
  Electronic Encyclopedia of Reagents for Organic Synthesis 8
  
  Pages: 1-12
- Data Source
  KAKENHI-PROJECT-18032074
[Journal Article] Synthesis of (9E)-Isoambrettolide, a Macrocyclic Musk Compound, Using the Effective Lactonization Promoted by SymmetricBenzoic Anhydrides with Basic Catalysts2006
- Author(s)
  Isamu SHIINA and Minako HASHIZUME
- Journal Title
  
  Tetrahedron 62
  
  Pages: 7934-7939
- Data Source
  KAKENHI-PROJECT-17350023
[Journal Article] 置換安息香酸無水物を用いる実用的縮合反応2006
- Author(s)
  椎名勇
- Journal Title
  
  ケミカルエンジニアリング 51
  
  Pages: 702-706
- Data Source
  KAKENHI-PROJECT-17350023
[Journal Article] Asymmetric Synthesis of 8 or 9-Membered Ring Natural Compounds Using a Rapid Lactonization to Form a Medium-sized Framework2006
- Author(s)
  Isamu SHIINA
- Journal Title
  
  Journal of the Mexican Chemical Society 50
  
  Pages: 262-262
- Data Source
  KAKENHI-PROJECT-17350023
[Journal Article] Synthesis of (9E)-Isoambrettolide, a Macrocyclic Musk Compound, Using the Effective Lactonization Promoted by Symmetric Benzoic Anhydrides with Basic Catalysts2006
- Author(s)
  Isamu SHIINA
- Journal Title
  
  Tetrahedron 62
  
  Pages: 7934-7939
- Data Source
  KAKENHI-PROJECT-18032074
[Journal Article] Computational Study on the Reaction Mechanism of the Key Thermal [4+4] Cycloaddition Reaction in the Biosynthesis of Epoxytwinol A2006
- Author(s)
  Isamu SHIINA
- Journal Title
  
  Organic Letters 8(印刷中)
- Data Source
  KAKENHI-PROJECT-17035079
[Journal Article] Asymmetric Synthesis of 8- or 9-Membered Ring Natural Compounds Using a Rapid Lactonization to Form a Medium-sized Framework2006
- Author(s)
  Isamu SHIINA
- Journal Title
  
  Journal of the Mexican Chemical Society 50
  
  Pages: 262-262
- Data Source
  KAKENHI-PROJECT-18032074
[Journal Article] 置換安息香酸無水物を用いる大員環および中員環ラクトン類の高速合成反応の開発2005
- Author(s)
  椎名勇
- Journal Title
  
  有機合成化学協会誌 63
  
  Pages: 2-17
- NAID
  10014102095
- Data Source
  KAKENHI-PROJECT-17350023
[Journal Article] Total Synthesis of Buergerinin F via Effective Construction of the Asymmetric Quaternary Carbons Using Enantioselective Aldol Reaction2005
- Author(s)
  Isamu SHIINA
- Journal Title
  
  Chemical Communications 2005
  
  Pages: 4062-4064
- Data Source
  KAKENHI-PROJECT-17035079
[Journal Article] 置換安息香酸無水物を用いる大員環および中員環ラクトン類の高速合成反応の開発2005
- Author(s)
  椎名勇
- Journal Title
  
  有機合成化学協会誌 63
  
  Pages: 2-17
- NAID
  10014102095
- Data Source
  KAKENHI-PROJECT-17035079
[Journal Article] Total Synthesis of Buergerinin F via Effective Construction of the Asymmetric Quaternary Carbons Using Enantioselective Aldol Reaction2005
- Author(s)
  Isamu SHIINA
- Journal Title
  
  Chemical Communications 2005
  
  Pages: 4062-4064
- Data Source
  KAKENHI-PROJECT-17350023
[Journal Article] Enantioselective Total Synthesis of Octalactin A Using Asymmetric Aldol Reactions and a Rapid Lactonization to form a Medium-sized Ring2005
- Author(s)
  Isamu SHIINA
- Journal Title
  
  Chemistry - a European Journal 11
  
  Pages: 6601-6608
- Data Source
  KAKENHI-PROJECT-17035079
[Journal Article] Enantioselective Synthesis of the Optically Active α-Methylene-β-hydroxy Esters, Equivalent Compounds to Morita-Baylis-Hillman Adducts, Using Successive Asymmetric Aldol Reaction and Oxidative Deselenization2005
- Author(s)
  Isamu SHIINA
- Journal Title
  
  Journal of Organic Chemistry 70
  
  Pages: 8103-8106
- Data Source
  KAKENHI-PROJECT-17035079
[Journal Article] Enantioselective Total Synthesis of Octalactin A Using Asymmetric Aldol Reactions and a Rapid Lactonization to form a Medium-sized Ring2005
- Author(s)
  Isamu SHIINA
- Journal Title
  
  Chemistry-a European Journal 11
  
  Pages: 6601-6608
- Data Source
  KAKENHI-PROJECT-17350023
[Journal Article] Enantioselective Synthesis of the Optically Active α-Methylene-β-hydroxy Esters, Equivalent Compounds to Morita-Baylis-Hillman Adducts, Using Successive Asymmetric Aldol Reaction and Oxidative Deselenization2005
- Author(s)
  Isamu SHIINA
- Journal Title
  
  Journal of Organic Chemistry 70
  
  Pages: 8103-8106
- Data Source
  KAKENHI-PROJECT-17350023
[Journal Article] Chemistry and Structural Determination of Botcinolides, Botcinins, and Botcinic Acids
- Author(s)
  Isamu SHIINA
- Journal Title
  
  Chemical Communications 2009
  
  Pages: 385-400
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17350023
[Patent] 安息香酸誘導体及び脱水縮合剤、並びにエステル及びラクトンの製造方法2018
- Inventor(s)
  椎名　勇
- Industrial Property Rights Holder
  椎名　勇
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-17H03024
[Patent] 『新規化合物及びその製造方法並びに抗がん剤』2012
- Inventor(s)
  (がん研究会)矢守隆夫、(東京理科大)椎名勇
- Industrial Property Rights Holder
  学校法人東京理科大学、公益財団法人がん研究会
- Industrial Property Number
  2012-087973
- Filing Date
  2012-04-06
- Data Source
  KAKENHI-PROJECT-22240092
[Patent] 『新規化合物及びその製造方法並びに抗がん剤』2012
- Inventor(s)
  (がん研)矢守隆夫、(東京理科大)椎名勇、中田健也、(東京電機大)長原礼宗
- Industrial Property Rights Holder
  学校法人東京理科大学、学校法人東京電機大学、公益財団法人がん研究会
- Industrial Property Number
  2012-104763
- Filing Date
  2012-05-06
- Data Source
  KAKENHI-PROJECT-22240092
[Patent] 光学活性2-ヒドロキシエステルの製造方法2010
- Inventor(s)
  椎名　勇，中田健也
- Industrial Property Rights Holder
  椎名　勇，中田健也
- Industrial Property Rights Type
  特許
- Filing Date
  2010-09-16
- Acquisition Date
  2014-09-05
- Overseas
- Data Source
  KAKENHI-PROJECT-22350044
[Patent] 特許2006
- Inventor(s)
  椎名勇, 佐野義之
- Industrial Property Rights Holder
  東京理科大学
- Industrial Property Number
  2006-018079
- Filing Date
  2006-01-26
- Data Source
  KAKENHI-PROJECT-17035079
[Patent] 特許2006
- Inventor(s)
  椎名勇, 佐野義之
- Industrial Property Rights Holder
  東京理科大学
- Industrial Property Number
  2006-018079
- Filing Date
  2006-01-26
- Data Source
  KAKENHI-PROJECT-17350023
[Patent] 特許2005
- Inventor(s)
  椎名勇
- Industrial Property Rights Holder
  東京理科大学
- Industrial Property Number
  2005-061558
- Filing Date
  2005-03-04
- Data Source
  KAKENHI-PROJECT-17350023
[Patent] 特許2005
- Inventor(s)
  椎名勇
- Industrial Property Rights Holder
  東京理科大学
- Industrial Property Number
  2005-061558
- Filing Date
  2005-03-04
- Data Source
  KAKENHI-PROJECT-17035079
[Presentation] 炎症誘発性プラットフォームを標的とする放射線防護剤の開発2023
- Author(s)
  森田明典、谷本大河、東優一、西山祐一、昌子紡己、村田貴嗣、小向杏佳、金井昭教、國井大誓、坂井卓磨、貞富凌、王冰、下川卓志、中田健也、武村直紀、齊藤達哉、稲葉俊哉、椎名勇
- Organizer
  第60回日本放射線腫瘍学会生物部会学術大会
- Data Source
  KAKENHI-PROJECT-23K27550
[Presentation] 抗炎症作用を有する新規化合物の放射線防護剤としての活性評価2021
- Author(s)
  谷本大河, 森田明典, 西山祐一, 村田貴嗣, 酒井杏樹, 金井昭教, 東優一, 越智進太郎, 國井大誓, 坂井卓磨, 貞富凌, 王冰, 下川卓志, 中田健也, 齊藤達哉, 稲葉俊哉, 椎名勇
- Organizer
  第58回生物部会学術大会・第49回放射線による制癌シンポジウム
- Data Source
  KAKENHI-PROJECT-19H03604
[Presentation] A novel immunomodulatory compound that prevents sub-total body irradiation-induced intestinal death2021
- Author(s)
  Taiga Tanimoto, Akinori Morita, Yuichi Nishiyama, Takatsugu Murata, Anjyu Sakai, Akinori Kanai, Yuichi Higashi, Taisei Kunii, Takuma Sakai, Ryo Sadatomi, Bing Wang, Takashi Shimokawa, Kenya Nakata, Naoki Takemura, Tatsuya Saitoh, Toshiya Inaba and Isamu Shiina
- Organizer
  The 64th Annual Meeting of the Japan Radiation Research Society
- Data Source
  KAKENHI-PROJECT-19H03604
[Presentation] 抗炎症作用を有する新規化合物の腸炎制御剤としての活性評価2021
- Author(s)
  東優一, 森田明典, 西山祐一, 村田貴嗣, 酒井杏樹, 金井昭教, 谷本大河, 坂井卓磨, 中田健也, 武村直紀, 齊藤達哉, 稲葉俊哉, 椎名勇
- Organizer
  第29回日本Cell Death学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03604
[Presentation] 二置換ナフタレン構造を有するジプロピオン酸を用いた動的速度論的光学分割法の開発2020
- Author(s)
  村田　貴嗣、高間　愛実、中田　健也、椎名　勇
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-17H03024
[Presentation] 不斉エステル化反応を用いたラセミ2-ヒドロキシ（アリール）ケトン類の速度論的光学分割ならびに遷移構造解析2020
- Author(s)
  村田　貴嗣、中田　健也、椎名　勇
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-17H03024
[Presentation] アリールジプロピオン酸類の動的速度論的光学分割法の開発研究2019
- Author(s)
  村田貴嗣、高間愛実、中田健也、椎名　勇
- Organizer
  日本化学会第99春季年会
- Data Source
  KAKENHI-PROJECT-17H03024
[Presentation] Mechanism of action of p53-regulating anti-cell death compound discovered by chemical library screening.2019
- Author(s)
  Ochi Shintaro, Satoh Hidetoshi, Ujita Shohei, Tada kasumi, Yosuke Matsushita, MiIzuno Kosuke, Deguchi Yuichi, Suzuki Keiji, Tanaka Yoshimasa, Ueda Hiroshi, Inaba Toshiya, Hosoi Yoshio, Aoki Shin and Akinori Morita
- Organizer
  he 62th Annual Meeting of the Japan Radiation Research Society
- Data Source
  KAKENHI-PROJECT-19H03604
[Presentation] MNBAを用いるω-アミノカルボン酸のマクロラクタム化反応2019
- Author(s)
  椎名　勇、野田有希、殿井貴之
- Organizer
  日本化学会第99春季年会
- Data Source
  KAKENHI-PROJECT-17H03024
[Presentation] ラセミ2-ヒドロキシケトンおよびその等価体の速度論光学分割2014
- Author(s)
  張キ・中原貴佳・石川凌・中田健也・椎名勇
- Organizer
  日本化学会第94春季年会
- Place of Presentation
  名古屋大学東山キャンパス
- Year and Date
  2014-03-27
- Data Source
  KAKENHI-PROJECT-23655045
[Presentation] ラセミ体のアミノ酸を光学活性なアミノ酸エステルへと変換する新規手法の発明2014
- Author(s)
  椎名　勇
- Organizer
  BioJapan 2014 World Business Forum
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-10-16
- Invited
- Data Source
  KAKENHI-PROJECT-22350044
[Presentation] ラセミカルボン酸の動的速度論的光学分割反応による光学活性含窒素化合物の合成2014
- Author(s)
  椎名　勇
- Organizer
  東京理科大学総合研究機構フォーラム2014
- Place of Presentation
  東京理科大学
- Year and Date
  2014-11-23
- Invited
- Data Source
  KAKENHI-PROJECT-22350044
[Presentation] 新規ゴルジ体機能阻害活性物質M-COPAの不斉全合成2014
- Author(s)
  椎名　勇
- Organizer
  文部科学省がん化学療法基盤支援活動第3回シンポジウム
- Place of Presentation
  万国津梁館（沖縄県名護市）
- Year and Date
  2014-05-12
- Invited
- Data Source
  KAKENHI-PROJECT-22350044
[Presentation] コプロフィリン誘導体（抗がん剤）の不斉全合成2014
- Author(s)
  椎名　勇
- Organizer
  京都大学大学院理学研究科特別講演会
- Place of Presentation
  京都大学
- Year and Date
  2014-10-30
- Invited
- Data Source
  KAKENHI-PROJECT-22350044
[Presentation] カルボン酸無水物を用いた高速脱水縮合反応の開発2014
- Author(s)
  椎名　勇
- Organizer
  京都大学大学院理学研究科特別講演会
- Place of Presentation
  京都大学
- Year and Date
  2014-10-29
- Invited
- Data Source
  KAKENHI-PROJECT-22350044
[Presentation] エリスロマイシン（抗菌剤）の合成研究2014
- Author(s)
  椎名　勇
- Organizer
  京都大学大学院理学研究科特別講演会
- Place of Presentation
  京都大学
- Year and Date
  2014-10-30
- Invited
- Data Source
  KAKENHI-PROJECT-22350044
[Presentation] ボトシニンおよびボトシノリド類（植物成長阻害剤）の不斉全合成2014
- Author(s)
  椎名　勇
- Organizer
  京都大学大学院理学研究科特別講演会
- Place of Presentation
  京都大学
- Year and Date
  2014-10-29
- Invited
- Data Source
  KAKENHI-PROJECT-22350044
[Presentation] テトラヒドロリプスタチン（抗肥満剤）の不斉全合成2014
- Author(s)
  椎名　勇
- Organizer
  京都大学大学院理学研究科特別講演会
- Place of Presentation
  京都大学
- Year and Date
  2014-10-30
- Invited
- Data Source
  KAKENHI-PROJECT-22350044
[Presentation] エポキシキノール類（血管新生阻害剤）の化学2014
- Author(s)
  椎名　勇
- Organizer
  京都大学大学院理学研究科特別講演会
- Place of Presentation
  京都大学
- Year and Date
  2014-10-29
- Invited
- Data Source
  KAKENHI-PROJECT-22350044
[Presentation] ラセミアミノ酸保護体の動的速度論光学分割による光学活性アミノ酸の合成2014
- Author(s)
  天花寺厚・中原貴佳・椎名勇
- Organizer
  日本化学会第94春季年会
- Place of Presentation
  名古屋大学東山キャンパス
- Year and Date
  2014-03-27
- Data Source
  KAKENHI-PROJECT-23655045
[Presentation] 不斉エステル化反応の開発2014
- Author(s)
  椎名　勇
- Organizer
  京都大学大学院理学研究科特別講演会
- Place of Presentation
  京都大学
- Year and Date
  2014-10-30
- Invited
- Data Source
  KAKENHI-PROJECT-22350044
[Presentation] カルボン酸エステル等価体を用いる不斉アルドール反応2014
- Author(s)
  椎名　勇
- Organizer
  京都大学大学院理学研究科特別講演会
- Place of Presentation
  京都大学
- Year and Date
  2014-10-29
- Invited
- Data Source
  KAKENHI-PROJECT-22350044
[Presentation] 計算化学によるトランスアシル化触媒(反応)の機能評価-抗肥満剤の合成を例として, 有機分子触媒による未来型分子変換2013
- Author(s)
  椎名勇
- Organizer
  第2回有機分子触媒
- Place of Presentation
  ラフォーレ倶楽部伊東温泉湯の庭
- Year and Date
  2013-09-14
- Data Source
  KAKENHI-PROJECT-23655045
[Presentation] 高選択的な脱水縮合反応の開発ならびに薬理活性化合物の不斉合成研究2013
- Author(s)
  椎名　勇
- Organizer
  平成24年度「日本化学会（第30回）学術賞」受賞講演
- Place of Presentation
  立命館大学びわこ・くさつキャンパス
- Year and Date
  2013-03-23
- Invited
- Data Source
  KAKENHI-PUBLICLY-23105544
[Presentation] Non-Enzymatic Dynamic Kinetic Resolution of Racemic 2-Arylalkanoic Acids Using Chiral Acyl-Transfer Catalysts2013
- Author(s)
  Isamu Shiina
- Organizer
  International Symposium on Homogeneous Chemical Reactivity
- Place of Presentation
  Ibaraki University
- Year and Date
  2013-06-14
- Data Source
  KAKENHI-PROJECT-23655045
[Presentation] ラセミ-2-アリール-2-フルオロプロピオン酸類の速度論的光学分割2013
- Author(s)
  天花寺厚・小野圭輔・中田健也・椎名勇
- Organizer
  日本化学会第93春季年会
- Place of Presentation
  立命館大学びわこ・くさつキャンパス
- Year and Date
  2013-03-24
- Data Source
  KAKENHI-PROJECT-23655045
[Presentation] ラセミ-2-アミノ-2-アリール酢酸類の静的および動的速度論光学分割反応の開発2013
- Author(s)
  中田健也・川西達也・小野圭輔・椎名勇
- Organizer
  日本化学会第93春季年会
- Place of Presentation
  立命館大学びわこ・くさつキャンパス
- Year and Date
  2013-03-24
- Data Source
  KAKENHI-PROJECT-23655045
[Presentation] 環状ラセミ-2-ヒドロキシカルボン酸誘導体の速度論的光学分割2013
- Author(s)
  中田健也・北島寛能・椎名勇
- Organizer
  日本化学会第93春季年会
- Place of Presentation
  立命館大学びわこ・くさつキャンパス
- Year and Date
  2013-03-24
- Data Source
  KAKENHI-PROJECT-23655045
[Presentation] ラセミ-2-ヒドロキシリン酸エステル類の速度論的光学分割2013
- Author(s)
  小野圭輔・椎名勇
- Organizer
  日本化学会第93春季年会
- Place of Presentation
  立命館大学びわこ・くさつキャンパス
- Year and Date
  2013-03-25
- Data Source
  KAKENHI-PROJECT-23655045
[Presentation] 高選択的な脱水縮合反応の開発ならびに薬理活性化合物の不斉合成研究2013
- Author(s)
  椎名勇
- Organizer
  日本化学会第93春季年会平成24年度日本化学会学術賞
- Place of Presentation
  立命館大学びわこ・くさつキャンパス
- Year and Date
  2013-03-24
- Data Source
  KAKENHI-PROJECT-23655045
[Presentation] ラセミ-2-ヒドロキシオキシムおよびその等価体の速度論的光学分割2013
- Author(s)
  中田健也・二見賢吾・張キ・中原貴佳・小野圭輔・椎名勇
- Organizer
  日本化学会第93春季年会
- Place of Presentation
  立命館大学びわこ・くさつキャンパス
- Year and Date
  2013-03-25
- Data Source
  KAKENHI-PROJECT-23655045
[Presentation] ニコチン酸無水物を用いたラセミ第2級アルコールの速度論的光学分割法の開発2013
- Author(s)
  中田健也・小野圭輔・椎名勇
- Organizer
  日本化学会第93春季年会
- Place of Presentation
  立命館大学びわこ・くさつキャンパス
- Year and Date
  2013-03-24
- Data Source
  KAKENHI-PROJECT-23655045
[Presentation] ラセミ-2-アリールプロピオン酸類の動的速度論光学分割の反応メカニズム解析2013
- Author(s)
  小野圭輔・天花寺厚・中田健也・椎名勇
- Organizer
  日本化学会第93春季年会
- Place of Presentation
  立命館大学びわこ・くさつキャンパス
- Year and Date
  2013-03-24
- Data Source
  KAKENHI-PROJECT-23655045
[Presentation] A New Method for Production of Chiral 2-Aryloxypropanoic Acids Using Effective Kinetic Resolution of Racemic 2-Aryloxycarboxylic Acids2012
- Author(s)
  Atsushi Tengeiji, Kenya Nakata, Keisuke Ono, Isamu Shiina
- Organizer
  11th Symposium on Chemical Approaches to Chirality
- Place of Presentation
  Tokyo University of Science
- Year and Date
  2012-09-26
- Data Source
  KAKENHI-PROJECT-23655045
[Presentation] ゴルジ体阻害活性を有する新奇双環性化合物の不斉全合成2012
- Author(s)
  椎名　勇
- Organizer
  「Cancer Cell Informaticsによる創薬研究会」第２回研究会(招待講演)
- Place of Presentation
  公益財団法人がん研究会
- Data Source
  KAKENHI-PROJECT-23655045
[Presentation] Non-Enzymatic Dynamic Kinetic Resolution of Racemic α-Arylalkanoic Acids2012
- Author(s)
  Isamu Shiina
- Organizer
  11th Symposium on Chemical Approaches to Chirality
- Place of Presentation
  Tokyo University of Science
- Year and Date
  2012-09-26
- Invited
- Data Source
  KAKENHI-PUBLICLY-23105544
[Presentation] 触媒的不斉縮合反応－計算科学による活性化剤の設計と展開2012
- Author(s)
  椎名　勇
- Organizer
  日本化学会関東支部講演会「進化する有機分子触媒－その最先端と展望－」
- Place of Presentation
  日本化学会７階ホール
- Year and Date
  2012-08-31
- Invited
- Data Source
  KAKENHI-PUBLICLY-23105544
[Presentation] JFCR39パネルを用いたリダイフェン類からの新規抗がん剤の探索2012
- Author(s)
  郭文智、椎名勇、旦慎吾、矢守隆夫
- Organizer
  第71回日本癌学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] ラセミ-2-アリールプロピオン酸類の活性化による動的速度論光学分割2012
- Author(s)
  椎名勇
- Organizer
  文部科学省科学研究費補助金新学術領域研究「直截的物質変換法をめざした分子活性化法の開発」第2回公開シンポジウム
- Place of Presentation
  京都大学桂キャンパス
- Year and Date
  2012-01-20
- Data Source
  KAKENHI-PUBLICLY-23105544
[Presentation] 触媒的不斉縮合反応 - 計算科学による活性化剤の設計と展開2012
- Author(s)
  椎名勇
- Organizer
  日本化学会関東支部講演会「進化する有機分子触媒-その最先端と展望-
- Place of Presentation
  日本化学会7階ホール
- Year and Date
  2012-08-31
- Data Source
  KAKENHI-PROJECT-23655045
[Presentation] ラセミ- 2-アリールプロピオン酸類の立体反転を伴う動的な速度論的光学分割法の開発2012
- Author(s)
  小野圭輔・中田健也・椎名勇
- Organizer
  日本化学会第92春季年会
- Place of Presentation
  慶応大学日吉キャンパス
- Year and Date
  2012-03-26
- Data Source
  KAKENHI-PROJECT-23655045
[Presentation] Non-Enzymatic Dynamic Kinetic Resolution of Racemic α-Arylalkanoic Acids2012
- Author(s)
  Isamu Shiina
- Organizer
  11th Symposium on Chemical Approaches to Chirality
- Place of Presentation
  Tokyo University of Science
- Year and Date
  2012-09-26
- Data Source
  KAKENHI-PROJECT-23655045
[Presentation] 不斉エステル化反応によるラセミ-2-アリールプロピオン酸類の動的速度論光学分割法の開発2012
- Author(s)
  小野圭輔・中田健也・椎名勇
- Organizer
  第102回有機合成シンポジウム
- Place of Presentation
  早稲田大学国際会議場
- Year and Date
  2012-11-09
- Data Source
  KAKENHI-PROJECT-23655045
[Presentation] ラセミ-2-アリールオキシプロピオン酸類の速度論的光学分割2012
- Author(s)
  天花寺厚・中田健也・小野圭輔・椎名勇
- Organizer
  日本化学会第92春季年会
- Place of Presentation
  慶応大学日吉キャンパス
- Year and Date
  2012-03-26
- Data Source
  KAKENHI-PROJECT-23655045
[Presentation] リダイフェン合成展開による創薬戦略2012
- Author(s)
  椎名　勇
- Organizer
  文部科学省がん支援・化学療法基盤支援活動　第２回シンポジウム(招待講演)
- Place of Presentation
  慶応大学日吉キャンパス
- Data Source
  KAKENHI-PROJECT-23655045
[Presentation] Dynamic Kinetic Resolution of 2-Arylpropanoic Acids via the Asymmetric Esterification2012
- Author(s)
  Keisuke Ono, Kenya Nakata, Isamu Shiina
- Organizer
  244th American Chemical Society National Meeting
- Place of Presentation
  Pennsylvania Convention Center, Philadelphia, PA
- Year and Date
  2012-08-19
- Data Source
  KAKENHI-PROJECT-23655045
[Presentation] 不斉エステル化反応によるラセミ2-アリールプロピオン酸類の速度論的光学分割2011
- Author(s)
  小野圭輔・中田健也・椎名勇
- Organizer
  第99回有機合成シンポジウム
- Place of Presentation
  慶応義塾大学薬学部
- Year and Date
  2011-06-15
- Data Source
  KAKENHI-PROJECT-23655045
[Presentation] ラセミ2-アリールプロピオン酸類の静的および動的速度論分割反応の開発2011
- Author(s)
  椎名　勇
- Organizer
  第４回有機触媒シンポジウム(招待講演)
- Place of Presentation
  東京理科大学
- Data Source
  KAKENHI-PROJECT-23655045
[Presentation] ラセミ2-アリールプロピオン酸類の静的および動的速度論分割反応の開発2011
- Author(s)
  椎名勇
- Organizer
  第4回有機触媒シンポジウム
- Place of Presentation
  東京理科大学神楽坂キャンパス
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-22350044
[Presentation] 人工不斉触媒を用いた静的および動的速度論分割反応の開発2011
- Author(s)
  椎名勇
- Organizer
  埼玉大学大学院理工学研究科講演会
- Place of Presentation
  埼玉大学工学部
- Year and Date
  2011-06-13
- Data Source
  KAKENHI-PROJECT-23655045
[Presentation] ラセミ2-アリールプロピオン酸類の静的および動的速度論分割反応の開発2011
- Author(s)
  椎名勇
- Organizer
  第4回有機触媒シンポジウム
- Place of Presentation
  東京理科大学神楽坂キャンパス
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-23655045
[Presentation] 不斉エステル化によるラセミアルコールおよびラセミカルボン酸の速度論的光学分割2010
- Author(s)
  椎名勇
- Organizer
  第4回日本化学会関東支部大会
- Place of Presentation
  筑波大学筑波キャンパス(招待講演)
- Year and Date
  2010-08-30
- Data Source
  KAKENHI-PROJECT-22350044
[Presentation] ペルオキシボトシニンDの不斉全合成2009
- Author(s)
  椎名勇(他2名)
- Organizer
  日本化学会第89春季年会
- Year and Date
  2009-03-30
- Data Source
  KAKENHI-PROJECT-17350023
[Presentation] ボトシニンAおよびBの不斉全合成2009
- Author(s)
  椎名勇(他3名)
- Organizer
  日本化学会第89春季年会
- Year and Date
  2009-03-30
- Data Source
  KAKENHI-PROJECT-17350023
[Presentation] ボトシニンD類縁体の合成ならびに抗菌活性2009
- Author(s)
  椎名勇(他2名)
- Organizer
  日本化学会第89春季年会
- Year and Date
  2009-03-30
- Data Source
  KAKENHI-PROJECT-17350023
[Presentation] アスタコラクチンの全合成研究2009
- Author(s)
  椎名勇(他2名)
- Organizer
  日本化学会第89春季年会
- Year and Date
  2009-03-28
- Data Source
  KAKENHI-PROJECT-17350023
[Presentation] ペルオキシボトシニン類の不斉合成研究2008
- Author(s)
  椎名勇(他2名)
- Organizer
  日本化学会第88春季年会
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-17350023
[Presentation] ボトシニン酸およびボトシニンEの全合成研究2008
- Author(s)
  椎名勇(他2名)
- Organizer
  日本化学会第88春季年会
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-17350023
[Presentation] 天然8員環状化合物アスタコラクチンの合成研究2008
- Author(s)
  椎名勇(他1名)
- Organizer
  日本化学会第88春季年会
- Year and Date
  2008-03-29
- Data Source
  KAKENHI-PROJECT-17350023
[Presentation] 2-エピボトシノリドおよびボトシニンC, D, Fの不斉全合成2008
- Author(s)
  椎名勇(他7名)
- Organizer
  日本化学会第88春季年会
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-17350023
[Presentation] ボトチノリド類修正構造の不斉合成研究2007
- Author(s)
  椎名勇(他4名)
- Organizer
  日本化学会第87春季年会
- Year and Date
  2007-03-25
- Data Source
  KAKENHI-PROJECT-17350023
[Presentation] 2-エピボトチノリド提案構造の不斉合成2007
- Author(s)
  椎名勇(他4名)
- Organizer
  日本化学会第87春季年会
- Year and Date
  2007-03-25
- Data Source
  KAKENHI-PROJECT-17350023
[Presentation] ボトチノリド類の側鎖の不斉合成ならびに9員環ラクトン部とのカップリング反応2006
- Author(s)
  椎名勇(他3名)
- Organizer
  日本化学会第86春季年会
- Year and Date
  2006-03-30
- Data Source
  KAKENHI-PROJECT-17350023
[Presentation] MNBAを用いた高速ラクトン形成法によるボトチノリド類の合成研究2006
- Author(s)
  椎名勇(他4名)
- Organizer
  日本化学会第86春季年会
- Year and Date
  2006-03-30
- Data Source
  KAKENHI-PROJECT-17350023
[Presentation] 計算化学によるトランスアシル化触媒（反応）の機能評価－抗肥満剤の合成を例として
- Author(s)
  椎名　勇
- Organizer
  有機分子触媒による未来型分子変換第２回有機分子触媒　若手セミナー招待講演
- Place of Presentation
  ラフォーレ倶楽部　伊東温泉　湯の庭
- Invited
- Data Source
  KAKENHI-PROJECT-23655045
[Presentation] Non-Enzymatic Dynamic Kinetic Resolution of Racemic 2-Arylalkanoic Acids Using Chiral Acyl-Transfer Catalysts
- Author(s)
  Isamu Shiina
- Organizer
  International Symposium on Homogeneous Chemical Reactivity
- Place of Presentation
  Ibaraki University
- Invited
- Data Source
  KAKENHI-PROJECT-22350044
[Presentation] ビシクロ[5.3.0]骨格を含む多置換ラクトン類の不斉全合成
- Author(s)
  椎名　勇
- Organizer
  第47回天然物化学談話会
- Place of Presentation
  阿蘇プラザホテル
- Invited
- Data Source
  KAKENHI-PROJECT-22350044
[Presentation] 高選択的な脱水縮合反応の開発ならびに薬理活性化合物の不斉合成研究
- Author(s)
  椎名　勇
- Organizer
  平成24年度「日本化学会（第30回）学術賞」受賞講演
- Place of Presentation
  立命館大学びわこ・くさつキャンパス
- Invited
- Data Source
  KAKENHI-PROJECT-23655045
[Presentation] 触媒的不斉縮合反応－計算科学による活性化剤の設計と展開
- Author(s)
  椎名　勇
- Organizer
  日本化学会関東支部講演会「進化する有機分子触媒－その最先端と展望－」
- Place of Presentation
  日本化学会７階ホール
- Invited
- Data Source
  KAKENHI-PROJECT-23655045
[Presentation] 触媒的不斉縮合反応－計算科学による活性化剤の設計と展開
- Author(s)
  椎名　勇
- Organizer
  日本化学会関東支部講演会「進化する有機分子触媒－その最先端と展望－」
- Place of Presentation
  日本化学会７階ホール
- Invited
- Data Source
  KAKENHI-PROJECT-22350044
[Presentation] 抗腫瘍活性化合物リダイフェン－合成・創薬展開からメカニズム解析まで
- Author(s)
  椎名　勇
- Organizer
  BioJapan 2013 World Business Forum
- Place of Presentation
  パシフィコ横浜
- Invited
- Data Source
  KAKENHI-PROJECT-23655045
[Presentation] Non-Enzymatic Dynamic Kinetic Resolution of Racemic α-Arylalkanoic Acids
- Author(s)
  Isamu Shiina
- Organizer
  11th Symposium on Chemical Approaches to Chirality
- Place of Presentation
  Tokyo University of Science
- Invited
- Data Source
  KAKENHI-PROJECT-22350044
[Presentation] 計算化学によるトランスアシル化触媒（反応）の機能評価－抗肥満剤の合成を例として
- Author(s)
  椎名勇
- Organizer
  有機分子触媒による未来型分子変換第２回有機分子触媒　若手セミナー招待講演
- Place of Presentation
  ラフォーレ倶楽部　伊東温泉　湯の庭
- Invited
- Data Source
  KAKENHI-PROJECT-22350044
[Presentation] 抗腫瘍活性化合物リダイフェン－合成・創薬展開からメカニズム解析まで
- Author(s)
  椎名勇
- Organizer
  BioJapan 2013 World Business Forum
- Place of Presentation
  パシフィコ横浜
- Invited
- Data Source
  KAKENHI-PROJECT-22350044
[Presentation] 高選択的な脱水縮合反応の開発ならびに薬理活性化合物の不斉合成研究
- Author(s)
  椎名　勇
- Organizer
  平成24年度「日本化学会（第30回）学術賞」受賞講演
- Place of Presentation
  立命館大学びわこ・くさつキャンパス
- Invited
- Data Source
  KAKENHI-PROJECT-22350044

1. TERUAKI Mukaiyama (60016003)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. MORITA Akinori (90334234)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
3. 青木伸 (00222472)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. 王冰 (10300914)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
5. 下川卓志 (20608137)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. 笹谷めぐみ (80423052)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. YAMORI Takao (60200854)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
8. DAN Shingo (70332202)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
9. KAWADA Manabu (20300808)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. NAKAMURA Hiroyuki (30274434)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KOJIMA Naoto (90420413)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. HIRONO Syuichi (30146328)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KOBAYASHI Shu (50195781)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. MANABE Kei (00251439)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. MATSUO Jun-ichi (50328580)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 中田健也 (00434019)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
17. 真板宣夫 (00404046)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 金井昭教 (60549567)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. YAMAMOTO Yoshihiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. HASEGAWA Makoto

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. TOYOSHIMA Megumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 小幡裕希

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
23. 西田俊朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 藤田直也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shiina Isamu 椎名 勇

SHIINA Isamu 椎名 勇

SHIMA Isamu 椎名 勇

Research Projects

Research Products

Co-Researchers

Development of Combination Radiation Therapy Drugs to Improve Cancer Control Rates by Regulating DNA Damage Response Molecules

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Development of radioprotectors that selectively protect normal tissues

Principal Investigator

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Development of asymmetric dehydration condensation reaction with kinetic or dynamic kinetic resolution of enantiomers and effective synthesis of non-natural amino acidsPrincipal Investigator

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ビニリデンジアセタート類の触媒活性化を利用した新規合成反応の開発Principal Investigator

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Development of C2-Symmetric Pyridine N-Oxides as New Nucleophilic Catalysts and Application for the Asymmetric SynthesisPrincipal Investigator

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Discovery of innovative molecular targeted drugs based on Cancer Cell Informatics

Principal Investigator

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Design of the Nonenzymatic Effective Dehydration Condensation Reaction and its Application to the Synthesis of Biologically Active MoleculesPrincipal Investigator

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芳香族求電子剤ならびに2種の不飽和型求核剤を用いるワンポット3成分連結反応の開発Principal Investigator

Principal Investigator

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Research Institution

高速縮合反応を基盤技術とする薬理活性天然中員環化合物の不斉全合成Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

新規中員環形成法を基盤技術とする植物成長阻害活性物質ボトチノリド類の不斉合成研究Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Asymmetric Total Synthesis of Medium-sized Lactones Using Rapid CyclizationPrincipal Investigator

Principal Investigator

Project Period (FY)

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タキソール類縁抗がん活性化合物の有効な合成法の確立Principal Investigator

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Study for stereoselective synthesis of oligosaccharides by new glycosylation methods

Principal Investigator

Shiina Isamu 椎名勇

SHIINA Isamu 椎名勇

SHIMA Isamu 椎名勇

[Book] エステル・アミドって何？　ラクトンって何？　－理科大発！ MNBAを用いた世界最速合成法の開発－2019