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kusumoto yutaka  楠本 豊

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Kusumoto Yutaka  楠本 豊

KUSUMOTO Yutaka  楠本 豊

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Researcher Number 40252689
Other IDs
Affiliation (Current) 2025: 大阪大谷大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help 2018 – 2024: 大阪大谷大学, 薬学部, 准教授
2016: 大阪大谷大学, 薬学部, 准教授
2000: 朝日大, 歯学部, 講師
1999: 朝日大学, 歯学部, 講師
1998: 朝日大学, 歯学部, 助手
1993 – 1997: Osaka University Faculty of Dentistry, Instructor, 歯学部, 助手
Review Section/Research Field
Principal Investigator
Conservative dentistry / Basic Section 57080:Social dentistry-related / Morphological basic dentistry
Except Principal Investigator
Conservative dentistry / Medium-sized Section 42:Veterinary medical science, animal science, and related fields / Basic Section 49030:Experimental pathology-related / Basic Section 57080:Social dentistry-related / Medium-sized Section 50:Oncology and related fields / Dermatology
Keywords
Principal Investigator
歯周病 / 歯周病原性細菌 / Porphyromonas gingivalis / ヒト歯肉上皮細胞 / 制御性T細胞 / IgE陽性B細胞 / 制御性T細胞 / 舌下免疫療法 / 長期生存型IgE産生細胞 / 皮膚感作 … More / I型アレルギー反応 / 免疫細胞クラスター / 口腔免疫応答 / 舌下免疫 / クラスター / 樹状細胞 / 口腔粘膜免疫 / 菌体表層成分 / 炎症細胞浸潤 / ケモカイン / 歯周炎 / RT-PCR / mRNA / 炎症性サイトカイン / 歯肉上皮細胞 / Polymerase Chain Reaction / 歯周治療 / Polymerase Chain Reaction(PCR) … More
Except Principal Investigator
歯周病 / 細胞周期 / 細胞動態 / 白血病幹細胞 / 免疫 / IgA / 腸管 / 乳腺 / KikGRマウス / IGF-I / CGF / PCR / CD44 / 歯肉線維芽細胞 / CD45R / T細胞 / B細胞 / 血清抗体価 / Porphyromonas gingivalis / 単細胞遺伝子発現解析 / 細胞移動 / In situ光ラベリング / 急性骨髄性白血病 / 唾液IgA抗体 / AID / 顎下唾液腺 / CD11c-YFPマウス / Iμ-Cα transcripts / IgAクラススイッチング / マウス舌下唾液腺 / 遺伝子改変マウス / 唾液分泌型IgA抗体 / 経鼻投与 / ケモカインレセプター / CD4陽性T細胞 / IgA陽性B細胞 / マウス唾液腺 / 樹状細胞 / NALT / クラスタリング / 形質細胞 / 急性転化 / 慢性骨髄性白血病 / KikGR / CCR10 / CCL28 / 生殖サイクル / 生体イメージング / 微生物 / 移行抗体 / 母子移行免疫 / 乳汁IgA / 母子移行型ワクチン / 腸内微生物 / パイエル板 / 抗体(IgA) / 乳汁 / ケモカイン / 接触性皮膚炎 / 細胞遊走 / シングルセル解析 / 免疫抑制 / 炎症性皮膚疾患 / 制御性T細胞 / Periodontal Ligament Cell / Heparin Binding IGF-I like Molecule / Growth Factor / Cementum / Periodontal Regeneration / Periodontitis / 不死化細胞株 / IGF-I前駆体 / 歯根膜由来細胞 / ヘパリン親和性IGF-I様増殖因子 / 増殖因子 / セメント質 / 歯周組織再生 / Genomic polymerase chain reaction / Effect of treatment / Periodontopathic bacteria / New quinolones / Local drug delivery system / Topical chemotherapeutic agent / Adult periodontitis / Periodontal treatment / genomic Polymerase Chain Reaction / 治療効果 / 歯周病関連細菌 / ニューキノロン系抗菌剤 / local drug delivery system / 局所化学療法 / 成人性歯周炎 / 歯周治療 / GINGIVAL FIBROBLAST / GINGIVAL EPITHELIAL CELL / SERUM ANTIBODY / PERIODONTOPATHIC BACTERIA / CYTOKINES / DIAGNOSIS / PERIODONTITIS / 炎症 / ELISA / 分子生物学的診断 / RT-PCR / mRNA / 歯肉上皮細胞 / 歯周病原性細菌 / PCR法 / サイトカイン / 病態診断 / Clonel Cell Line / Differentiation / Periodontal Ligament Cells / Regeneration / Wound Healing / Periodontal Disease / 創傷治療 / bFGFレセプター / bFGF / 細胞株 / 細胞分化 / 歯根膜細胞 / 組織再生 / 創傷治癒 / VLA integrin / gingival fibroblast / cell adhesion molecule / Autologous mixed lymphocyte reaction / T cells / periodontal disease / 多クロ-ン性B細胞活性化 / 歯周炎 / 自己反応性T細胞 / インテグリン / T細胞クローン / VLA-4 / 細胞接着分子 / 自己リンパ球混合培養反応 / 歯周疾患 / シグナル伝達 / LPSレセプター / LPS低応答性 / lipopolysaccharide (LPS) / 抗原特異的T細胞 / 線毛抗原 Less
  • Research Projects

    (20 results)
  • Research Products

    (14 results)
  • Co-Researchers

    (36 People)
  •  Clustering of plasma cells for a comprehensive understanding of immune function in the mammary glands

    • Principal Investigator
      野地 智法
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 42:Veterinary medical science, animal science, and related fields
    • Research Institution
      Tohoku University
  •  舌下免疫で誘導される制御性T細胞の組織間移動によるI型アレルギー抑制機序の解明Principal Investigator

    • Principal Investigator
      楠本 豊
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57080:Social dentistry-related
    • Research Institution
      Osaka Ohtani University
  •  Identification of novel therapeutic target molecules based on correlation between leukemia stem cell heterogeneity and in vivo dynamics

    • Principal Investigator
      戸村 道夫
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Osaka Ohtani University
  •  Elucidation of in vivo kinetics of leukemia cell differentiation and proliferation in blast crisis

    • Principal Investigator
      戸村 道夫
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 50:Oncology and related fields
    • Research Institution
      Osaka Ohtani University
  •  Dynamic in vivo fluorescence imaging analysis of Immunocytes relevant to salivary IgA production.

    • Principal Investigator
      KATAOKA Kosuke
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 57080:Social dentistry-related
    • Research Institution
      The University of Tokushima
  •  Role of Immune Cell Clusters in Sublingual Mucosal Tissue in Oral Immune ResponsesPrincipal Investigator

    • Principal Investigator
      Kusumoto Yutaka
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57080:Social dentistry-related
    • Research Institution
      Osaka Ohtani University
  •  Elucidation of reproductive cycle-specific immunological and microbiological dynamics using bioimaging

    • Principal Investigator
      Nochi Tomonori
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 42:Veterinary medical science, animal science, and related fields
    • Research Institution
      Tohoku University
  •  Establishment of skin inflammation drug to accumulate high-functional regulatory T cells by single-cell gene expression analysis

    • Principal Investigator
      Ikebuchi Ryoyo
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Dermatology
    • Research Institution
      Osaka Ohtani University
  •  歯周病原因子のヒト歯肉上皮細胞活性化機構に関する分子細胞生物学的研究Principal Investigator

    • Principal Investigator
      楠本 豊
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Asahi University
  •  歯周炎病巣における上皮層直下粘膜固有層への炎症細胞浸潤に対する歯肉上皮細胞の役割Principal Investigator

    • Principal Investigator
      楠本 豊
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Conservative dentistry
    • Research Institution
      Asahi University
      Osaka University
  •  Establishment of molecular biological diagnostic strategies for periodontal diseases

    • Principal Investigator
      OKADA Hiroshi
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Conservative dentistry
    • Research Institution
      Osaka University
  •  The development of controlled release-drug utilizing new quinolones for perlodontitis

    • Principal Investigator
      OKADA Hiroshi
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Conservative dentistry
    • Research Institution
      Osaka University
  •  Characteristic Growth Factor Actions Involved in Periodontal Regeneration

    • Principal Investigator
      MURAKAMI Shinya
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Conservative dentistry
    • Research Institution
      Osaka University
  •  Porhyromonas gingivalis LPSによるB細胞活性化機構の解析

    • Principal Investigator
      島内 英俊
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Conservative dentistry
    • Research Institution
      Osaka University
  •  歯周病原性細菌による歯肉上皮細胞の活性化Principal Investigator

    • Principal Investigator
      楠本 豊
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Conservative dentistry
    • Research Institution
      Osaka University
  •  歯周病患者における抗原特異的T細胞機能の解析

    • Principal Investigator
      SHIMAUCHI Hidetoshi
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Conservative dentistry
    • Research Institution
      Osaka University
  •  歯周病原性細菌の微量検出法による歯周治療効果の評価Principal Investigator

    • Principal Investigator
      楠本 豊
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Conservative dentistry
    • Research Institution
      Osaka University
  •  Study for the Differentiation Mechanisms of Periodontal Ligament Cells

    • Principal Investigator
      MIKI Yasuo
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Conservative dentistry
    • Research Institution
      Osaka University
  •  歯肉溝における歯周病原性細菌の微量検出ならびにその存否と病態の関連について(歯周治療後の再定着について)Principal Investigator

    • Principal Investigator
      楠本 豊
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Conservative dentistry
    • Research Institution
      Osaka University
  •  Immunoregulatory Mechanisms in Adult Periodontitis

    • Principal Investigator
      OKADA Hiroshi
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Conservative dentistry
    • Research Institution
      Osaka University

All 2024 2023 2022 2021 2019 2018 2016 2015

All Journal Article Presentation

  • [Journal Article] The gut microbiota induces Peyer’s-patch-dependent secretion of maternal IgA into milk2021

    • Author(s)
      Usami Katsuki、Niimi Kanae、Matsuo Ayumi、Suyama Yoshihisa、Sakai Yoshifumi、Sato Shintaro、Fujihashi Kohtaro、Kiyono Hiroshi、Uchino Saeka、Furukawa Mutsumi、Islam Jahidul、etc
    • Journal Title

      Cell Reports

      Volume: 36 Issue: 10 Pages: 109655-109655

    • DOI

      10.1016/j.celrep.2021.109655

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K15478, KAKENHI-PROJECT-18H02326, KAKENHI-PROJECT-18H03969, KAKENHI-PROJECT-19H03702, KAKENHI-PROJECT-20H03856, KAKENHI-PROJECT-20K20495, KAKENHI-PROJECT-21K19176, KAKENHI-PROJECT-21H02340
  • [Presentation] 3D-visualization of sublingual immune cell clusters with sensory neurons2024

    • Author(s)
      Mayuko Hashimoto, Tetsushi Hoshida, Yutaka Kusumoto, Atsushi Miyawaki, Michio Tomura
    • Organizer
      第52回 日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K10327
  • [Presentation] KikGRマウス骨髄キメラマウスを用いた舌下免疫細胞クラスター構成細胞の解析2023

    • Author(s)
      野村真理恵、岩佐悠紀、水内龍、坂本響哉、神谷幸香、田中優斗、橋本茉由子、楠本豊、戸村道夫
    • Organizer
      第73回 日本薬学会関西支部総会・大会
    • Data Source
      KAKENHI-PROJECT-22K10327
  • [Presentation] テープストリッピング法によりアレルゲン投与したマウス骨髄における長期生存型IgE産生細胞の検出2023

    • Author(s)
      水内龍、野村真理恵、神谷幸香、坂本響哉、岩佐悠紀、大馬崎香綸、岡村亘起、橋本茉由子、楠本豊、戸村道夫
    • Organizer
      第73回 日本薬学会関西支部総会・大会
    • Data Source
      KAKENHI-PROJECT-22K10327
  • [Presentation] Detailed analysis of dendritic cells (DCs) and T cell subsets comprising sublingual clusters DC - T cell clusters (SDTCs)2022

    • Author(s)
      Kusumoto Y., Kaisho T., Hemmi H.,Moriya T., Tomura M.
    • Organizer
      第14回寄生虫感染免疫研究会
    • Data Source
      KAKENHI-PROJECT-18K09930
  • [Presentation] 特異的光ラベルによる舌下免疫細胞クラスター構成細胞の解析2022

    • Author(s)
      楠本 豊、片岡宏介
    • Organizer
      第64回 歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-22K10327
  • [Presentation] 舌下粘膜に存在する免疫細胞クラスターの構成細胞の解析2022

    • Author(s)
      田中優斗、熊谷僚斗、坂本響哉、橋本茉由子、楠本豊、戸村道夫
    • Organizer
      第72回 日本薬学会関西支部総会・大会
    • Data Source
      KAKENHI-PROJECT-22K10327
  • [Presentation] Detection of migration of IgE+ cells from draining Lymph node after skin sensitization.2022

    • Author(s)
      Mayuko Hashimoto, Yutaka Kusumoto, Takahiro Adachi, Michio Tomura
    • Organizer
      第51回 日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K10327
  • [Presentation] Sublingual dendritic cell(DC)-T cell clusters and distribution of DCs in the oral cavity2021

    • Author(s)
      Kusumoto Y., Kaisho T., Hemmi H., Katakai T., Honda T., Kikuta J., Kataoka K., Moriya T., Ishii M., Kabashima K., Tomura M.
    • Organizer
      第50回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K09930
  • [Presentation] DC-cluster formation in sublingual mucosa by sublingual immunization2019

    • Author(s)
      楠本豊、片岡宏介
    • Organizer
      第61回 歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-18K09930
  • [Presentation] 舌下面への抗原投与による舌下粘膜における樹状細胞クラスターの形成誘導2019

    • Author(s)
      岡田尚子、楠本豊、小川大将、有村綾菜、重春舞、山元純哉、西村実紗、西居亜希子、守屋大樹、戸村道夫
    • Organizer
      第69回 日本薬学会関西支部総会・大会
    • Data Source
      KAKENHI-PROJECT-18K09930
  • [Presentation] 口腔粘膜における樹状細胞とそのクラスターの分布2018

    • Author(s)
      楠本 豊、片岡宏介
    • Organizer
      第60回 歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-18K09930
  • [Presentation] Single-cell Gene & Protein Expression Analysis Revealed Unique Functional Subsets of Regulatory T Cells2016

    • Author(s)
      Ryoyo IKEBUCHI, Shunsuke TERAGUCHI, Alexis VANDENBON, Yasutaka NAKANISHI, Taiki MORIYA, Hiromi OKUYAMA, Yutaka KUSUMOTO, Tetsuya HONDA, Michio TOMURA
    • Organizer
      International Conference on Single Cell Research 2016
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2016-11-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19687
  • [Presentation] Single-cell gene expression analysis revealed that CD43+ CCR5+ Treg cells are a main subset of Il10 gene-expressing cells in contact hyper sensitivity model2015

    • Author(s)
      IKEBUCHI Ryoyo, NAKANISHI Yasutaka, MORIYA Taiki, OKUYAMA Hiromi, KUSUMOTO Yutaka, HONDA Tetsuya, TOMURA Michio
    • Organizer
      第44回日本免疫学会学術集会
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2015-11-18
    • Data Source
      KAKENHI-PROJECT-15K19687
  • 1.  TOMURA Michio (30314321)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 10 results
  • 2.  SHIMAUCHI Hidetoshi (70187425)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 3.  MURAKAMI Shinya (70239490)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 4.  OKADA Hiroshi (40038865)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 5.  SHIMABUKURO Yoshio (50231361)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 6.  MORIYA Taiki (30759759)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 5 results
  • 7.  MIKI Yasuo (80165993)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  KATAOKA Kosuke (50283792)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 9.  KITAMURA Masahiro (10243247)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  NOZAKI Takenori (30263304)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  Nochi Tomonori (10708001)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  北澤 春樹 (10204885)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  米山 裕 (10220774)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  岩崎 正幸 (70790913)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  橋本 茉由子 (60943628)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 16.  IKEZAWA Kazuhiro (80294114)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  Ikebuchi Ryoyo (00747529)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 18.  TERAGUCHI Shunsuke (00467276)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 19.  NAKAYAMA Takashi (60319663)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  MATSUO Kazuhiko (70615921)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  伊藤 博夫 (40213079)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  原田 泰 (10181025)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  木村 重信 (10177917)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  佐保 輝之 (10263295)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  Alexis Vandenbon (60570140)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  麻生 久 (50241625)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  渡邊 康一 (80261494)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  古川 睦実 (80914267)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  安達 貴弘 (50222625)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 30.  土居 貴士 (20388375)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  河村 佳穂里 (20737019)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  三宅 達郎 (40200141)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  橋井 佳子 (60343258)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  MINAMI Shinzaburo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  イスラム ジャヒドゥル
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 36.  VANDENBON ALEXIS
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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