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Soma Toshihiro  相馬 俊裕

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… Alternative Names

相馬 俊裕  ソウマ トシヒロ

SOMA Toshihiro  相馬 俊裕

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Researcher Number 40273619
Affiliation (Current) 2025: 兵庫医科大学, 医学部, 非常勤講師
Affiliation (based on the past Project Information) *help 2018 – 2019: 兵庫医科大学, 医学部, 非常勤講師
2016 – 2017: 兵庫医科大学, 医学部, 准教授
2014: 兵庫医科大学, 医学部, 准教授
2013: 兵庫医科大学, 血液内科学, 准教授
2006: 独立行政法人国立病院機構大阪南医療センター, 臨床検査部, 部長 … More
2005: 独立行政法人国立病院機構(大阪南医療センター臨床研究部), 臨床検査部, 部長
2004: National Hospital Organization, Osaka Minami Medical Center, Clinical Research Institute, Department of Clinical Laboratory, Director, 大阪南医療センター・臨床検査部, 部長
2004: 独立行政法人国立病院機構大阪南医療センター, 臨床検査部, 部長
2003: 独立行政法人国立病院機構大阪南医療センター, 臨床研究部・免疫循環調節室, 室長
1999 – 2001: 大阪大学, 医学系研究科, 助手
2000: 阪大, 医学(系)研究科, 助手
1996 – 1998: Osaka Univ.Med.School, Dept.of Med.III,Assistant prof., 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Hematology / Biomedical engineering/Biological material science
Except Principal Investigator
Hematology / Tumor therapeutics / Laboratory animal science / Pathological medical chemistry / Neuroscience in general / Neurology / Human pathology
Keywords
Principal Investigator
臍帯血 / 造血幹細胞 / Scid / NOD / nonwoven fabrics / three-dimensional culture / cord blood / reactor / porous membrane / co-culture … More / bone marrow transplantation / hematopoietic cells / 不織布 / 三次元培養 / リアクター / 多孔性膜 / 共培養 / 骨髄移植 / 造血細胞 / EX VIVO expantion, / Cord Blood, / Hematopoietic stem cell, / 可溶性IL-6受容体 / 造血前駆細胞 / 体外増幅 / 支持細胞 / 異種移植 … More
Except Principal Investigator
WT1 / 白血病 / WT1遺伝子 / leukemia / 間葉系幹細胞 / ウイルムス腫瘍遺伝子 / 骨髄移植 / 免疫療法 / minimal residual disease / WT1 gene / 微小残存白血病 / oncogene / tumor suppressor gene / 造血幹細胞 / leukemogenesis / apoptosis / 微小残存病変 / MRD / WT1アッセイ / 血栓性微小血管障害 / エクソソーム / 免疫抑制 / 血管内皮細胞 / 乾癬様皮膚炎 / 乾癬 / 移植後血栓性微小血管障害 / 移植片対宿主病 / 造血幹細胞移植 / ヒト化マウス / 間葉系細胞 / 多発性骨髄腫 / 生着促進 / 骨髄内移植 / 骨髄内臍帯血移植 / 臍帯血移植 / clinical trial / immunotherapy / 臨床試験 / 癌ワクチン / bone marrow transplantation / キメラ遺伝子 / 微少残存腫瘍 / Lung cancer / 肺癌 / The WT1 gene / WWドメイン / アポトーシス / Leukemia / hematopoietic stem cell / 微小残存腫瘍 / hematopoietic progenitor cells / 32D cells / M期 / G_2 / Stat3 / 32D細胞 / がん遺伝子 / がん抑制遺伝子 / Wilms tumor gene / 血管分化 / 神経分化 / ペリサイト / 虚血 / 脳梗塞 / 多能性幹細胞 / 神経幹細胞 / 血管新生 / 神経再生 / NIRS / シルデナフィル / CD34 / ジストロフィン異常症 / ホスホジエステラーゼ5阻害剤 / 末梢血血管内皮前駆細胞: / ホスホジエステラーゼ5阻害剤 / 末梢血血管内皮前駆細胞 / 微小循環障害 / Duchenne型筋ジストロフィー / 予後因子 / 免疫組織化学 / 悪性リンパ腫 / 骨髄異形成症候群 / MDS / AML / signal transduction / Leukemogenesis / real time PCR / WT1 assay / ドナーリンパ球輸注 / 化学療法 / 微少残存病変 Less
  • Research Projects

    (24 results)
  • Research Products

    (11 results)
  • Co-Researchers

    (37 People)
  •  An immunotherapy model for hematopoietic malignancies (multiple myeloma) using humanized mice

    • Principal Investigator
      Yoshihara Satoshi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory animal science
    • Research Institution
      Hyogo Medical University
  •  Use of amnion-derived mesenchymal stem cells for treatment of immune dysfunction after hematopoietic stem cell transplantation

    • Principal Investigator
      Fujimori Yoshihiro
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor therapeutics
    • Research Institution
      Hyogo Medical University
  •  Novel therapeutic strategy by intrabone marrow co-transplantation of cord blood and cord-derived mesenchymal stem cells

    • Principal Investigator
      OKADA Masaya
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor therapeutics
    • Research Institution
      Hyogo Medical University
  •  Examination of angiogenic potential of brain-derived injury-induced neural stem cells

    • Principal Investigator
      NAKAGOMI Takayuki
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neuroscience in general
    • Research Institution
      Hyogo Medical University
  •  Development of biomarker and the new therapeutic method for Duchenne muscular dystrophy

    • Principal Investigator
      SAITO Toshio
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Toneyama National Hospital
  •  悪性リンパ腫予後因子の免疫組織化学的評価システムの構築に関する研究

    • Principal Investigator
      中塚 伸一
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Human pathology
    • Research Institution
      National Hospital Organization Osaka-Minami Medical Center
  •  Low-cost ex-vivo expansion system for hematopoietic progenitor cells employing a membrane-separated coculture system of hematopoietic cells and stromal cell line.Principal Investigator

    • Principal Investigator
      SOMA Toshihiro, 吉田 敏臣
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      National Hospital Organization, Osaka Minami Medical Center, Clinical Research Institute
      Osaka University
  •  Immunotherapy against leukemia targeting WT1 product

    • Principal Investigator
      OKA Yoshihiro
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Osaka University
  •  白血病の原因遺伝子ろしてのWT1遺伝子の分子生物学的機能の解析

    • Principal Investigator
      小川 啓恭
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Osaka University
  •  WT1アッセイを用いた、白血病と骨髄異形成症候群の治療の個別化

    • Principal Investigator
      杉山 治夫
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Osaka University
  •  性差による競合的ヒト/マウス異種移植実験系を用いた人造血幹細胞の動態解析Principal Investigator

    • Principal Investigator
      相馬 俊裕
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Osaka University
  •  The role of the tumor suppressor gene WT1 in human leukemogenesis.

    • Principal Investigator
      SUGIYAMA Haruo
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Hematology
    • Research Institution
      Osaka University
  •  Oncogenic role of the Wilms' tumor gene in tumorigenesis of lung cancer

    • Principal Investigator
      OJI Yusuke
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Osaka University
  •  Individualized therapy of patients with leukemia based on WT1 assay.

    • Principal Investigator
      HIROYASU Ogawa
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Osaka University
  •  白血病の遺伝子診断と白血病治療の個別化

    • Principal Investigator
      杉山 治夫
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Field
      Hematology
    • Research Institution
      Osaka University
  •  白血病の原因遺伝子としてのWT1遺伝子の分子生物学的機能の解析

    • Principal Investigator
      小川 啓恭
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Osaka University
  •  WT1アッセイを用いた、白血病と骨髄異形成症候群の治療の個別化

    • Principal Investigator
      杉山 治夫
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Osaka University
  •  微小残存白血病細胞の新しい検出法の確立による白血病の個性化した治療法の開発

    • Principal Investigator
      杉山 治夫
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Analysis of roles of tumor suppressor gene WT1 in human leukemogenesis.

    • Principal Investigator
      SUGIYAMA Haruo
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Osaka University
  •  Wilms tumor gene(WT1)expression in leukemic and normal hematopoietic stem cells.

    • Principal Investigator
      OGAWA Hiroyasu
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Osaka University
  •  DEVELOPMENT OF QUANTITATIVE ASSAY SYSTEM OF HUMAN HEMATOPOIETIC STEM CELL USING NOD/SCID MOUSE AND STROMA CELL LINE MS5Principal Investigator

    • Principal Investigator
      SOMA Toshihiro
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Osaka University
  •  微少残存白血病細胞の新しい検出法の確立による白血病の新しい治療法の開発

    • Principal Investigator
      SUGIYAMA Haruo
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  レトロウイルスによる遺伝子導入を用いたヒト成人血液幹細胞増幅条件の探求Principal Investigator

    • Principal Investigator
      相馬 俊裕
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Osaka University
  •  Role of the tumor suppressor gene WT1 in human leukemogenesis.

    • Principal Investigator
      SUGIYAMA Haruo
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Osaka University

All 2019 2018 2017 2012

All Journal Article Presentation

  • [Journal Article] Safety and efficacy of amnion-derived mesenchymal stem cells (AM01) in patients with steroid-refractory acute graft-versus-host disease after allogeneic haematopoietic stem cell transplantation: a study protocol for a phase I/II Japanese trial2019

    • Author(s)
      Yamahara K、Hamada A、Soma T、Okamoto R、Okada M、Yoshihara S、Yoshihara K、Ikegame K、Tamaki H、Kaida K、Inoue T、Ohsugi Y、Nishikawa H、Hayashi H、Ito Y、Iijima H、Ohnishi S、Hashimoto D、Isoe T、Teshima T、Ogawa H、Sato N、Fujimori Y
    • Journal Title

      BMJ Open

      Volume: 9 Issue: 7 Pages: e026403-e026403

    • DOI

      10.1136/bmjopen-2018-026403

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07142, KAKENHI-PROJECT-17K07228
  • [Journal Article] Low incidence of HHV‐6 reactivation in haploidentical hematopoietic stem cell transplantation with corticosteroid as graft‐vs‐host disease prophylaxis compared with cord blood transplantation2019

    • Author(s)
      Tamaki Hiroya、Ikegame Kazuhiro、Yoshihara Satoshi、Kaida Katsuji、Yoshihara Kyoko、Inoue Takayuki、Kato Ruri、Nakata Jun、Fujioka Tatsuya、Soma Toshihiro、Okada Masaya、Ogawa Hiroyasu
    • Journal Title

      Transplant Infectious Disease

      Volume: - Issue: 3

    • DOI

      10.1111/tid.13073

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K07185, KAKENHI-PROJECT-16K09882, KAKENHI-PROJECT-17K07142
  • [Journal Article] 急性GVHD・クローン病に対する羊膜由来間葉系幹細胞の医師主導治験 -兵庫医科大学発・初認定ベンチャーによる開発をめざして-2018

    • Author(s)
      山原 研一, 濱田 彰子, 大西 俊介, 相馬 俊裕, 岡本 里香, 中村 志郎, 岡田 昌也, 吉原 哲, 吉原 享子, 橋本 大吾, 磯江 敏幸, 豊嶋 崇徳, 佐藤 典宏, 藤盛 好啓
    • Journal Title

      兵庫医科大学医学会雑誌

      Volume: 43 Pages: 41-45

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K07185
  • [Presentation] 生物由来原料基準を満たす国産ウシ血小板溶解物「NeoSERA」を原材料とする羊膜由来間葉系幹細胞の細胞製剤化2019

    • Author(s)
      山原研一, 浜田彰子, 黒田将子, 池本純子, 吉原享子, 吉原哲, 岡田昌也, 橋本大吾, 相馬俊裕, 豊嶋崇徳, 藤盛好啓
    • Organizer
      第67回日本輸血・細胞治療学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K07142
  • [Presentation] Bovine platelet lysate-derived serum NeoSERA is safe, less ethical and powerful alternative to fetal bovine serum for the culture of mesenchymal stem cells.2019

    • Author(s)
      Yamahara K, Sudo T, Hamada A, Yoshihara K, Yoshihara S, Okada M, Soma T, Ohnishi S, Fujimori Y
    • Organizer
      International Society for Stem Cell Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07228
  • [Presentation] 当院におけるテムセルHS注の運用2018

    • Author(s)
      池本純子、杉山寛貴、原田由紀、大塚真哉、小野本仁美、入江玲子、 奥田典子、村田理恵、前田和宏、吉原享子、吉原哲、岡田昌也、 山原研一、相馬俊裕、藤盛好啓
    • Organizer
      第40回日本造血細胞移植学会総会
    • Data Source
      KAKENHI-PROJECT-17K07142
  • [Presentation] Adult bovine-derived leukocyte and platelet-rich plasma (L-PRP) is safe, less ethical, economical and powerful alternative to fetal bovine serum for the culture of mesenchymal stem cells.2017

    • Author(s)
      Yamahara K, Sudo T, Hamada A, Kuroda S, Yoshihara K, Yoshihara S, Okada M,Soma T, Onishi S, Fujimori Y.
    • Organizer
      International Society of Stem Cell Research (ISSCR) 2017 Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07228
  • [Presentation] Frailty score-based treatment strategy for transplant-ineligible elderly myeloma patients2017

    • Author(s)
      吉原享子、吉原哲、池本純子、岡田昌也、山原研一、相馬俊裕、藤盛好啓
    • Organizer
      第79回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K07142
  • [Presentation] 当院におけるテムセルHS注の管理体制の構築2017

    • Author(s)
      杉山 寛貴, 原田 由紀, 大塚 真哉, 小野本 仁美, 入江 玲子, 奥田 典子, 村田 理恵, 前田 和宏, 池本 純子, 吉原 享子, 吉原 哲, 山原 研一, 相馬 俊裕, 藤盛 好啓
    • Organizer
      第65回日本輸血・細胞治療学会総会
    • Data Source
      KAKENHI-PROJECT-17K07142
  • [Presentation] 神経筋疾患の血管新生マーカー2012

    • Author(s)
      齊藤利雄,田浦映恵,相馬俊裕,松村剛,猪山昭徳,木村紀久,藤村晴俊,佐古田三郎
    • Organizer
      第53回日本神経学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2012-05-25
    • Data Source
      KAKENHI-PROJECT-23591290
  • [Presentation] Circulating CD34-positive cells in muscular dystrophy2012

    • Author(s)
      Saito T, Kikuchi-Taura A, Soma T, Iyama A, Kimura N, Matsumura T, Fujimura H, Sakoda S
    • Organizer
      The 11th Annual Asian and Oceanian Myology Center (AOMC) Scientific Meeting
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-23591290
  • 1.  OKA Yoshihiro (20273691)
    # of Collaborated Projects: 15 results
    # of Collaborated Products: 0 results
  • 2.  OGAWA Hiroyasu (80194447)
    # of Collaborated Projects: 14 results
    # of Collaborated Products: 0 results
  • 3.  OJI Yusuke (20294100)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 0 results
  • 4.  SUGIYAMA Haruo (70162906)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 5.  TATEKAWA Toyoshi
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 6.  MIYAKE Seigo (60294097)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 7.  OKADA Masaya (00309452)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 8.  Yoshihara Satoshi (90461037)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 9.  山上 保 (60416253)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  SAITO Toshio (60538776)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  OHIRA Yoshinobu (50185378)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  FUJIMURA Harutoshi (20263246)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 13.  MATSUMURA Tsuyoshi (30549366)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 14.  SAKODA Saburo (00178625)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 15.  TAURA Akie (80644533)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 16.  TADA Satoru (70626530)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  YAMADERA Misaki (90649906)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  NAKAGOMI Takayuki (80434950)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  MATSUYAMA Tomohiro (10219529)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  TAGUCHI Akihiko (10359276)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  TAKAGI Mutsumi (20263212)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  Fujimori Yoshihiro (20229058)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 23.  中塚 伸一 (90303940)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  青笹 克之 (30115985)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  川上 学 (50372610)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  玉置 広哉 (70416254)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  藤田 茂樹 (10379175)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  吉田 敏臣 (00029290)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  池亀 和博 (20372609)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 30.  吉原 享子 (80595265)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 31.  谷 慶彦
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  MENSSEN H.D.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  MARGOLIS Dav
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  坪井 昭博
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  AKIHIRO Tsuboi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  平山 文也
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  SOAITO Toshio
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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