Aoyama Hiroshi 青山洋史

… Alternative Names

AOYAMA Hiroshi 青山洋史

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Researcher Number	40374699
Other IDs
Affiliation (Current)	2025: 東京薬科大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2015 – 2017: 東京薬科大学, 薬学部, 准教授 2013: 東京大学, 分子細胞生物学研究所, 助教 2012 – 2013: 東京薬科大学, 薬学部, 准教授 2007 – 2009: The University of Tokyo, 分子細胞生物学研究所, 助教
Review Section/Research Field	Principal Investigator Drug development chemistry / Chemical pharmacy Except Principal Investigator Drug development chemistry
Keywords	Principal Investigator ホスホン酸エステル / 血液凝固 / 酵素阻害 / セリンプロテアーゼ / トロンビン / 非競合阻害剤 / ホスホネート / セリンプロテアーゼ阻害剤 / PTP / 虚血性疾患 … More / C型肝炎 / ミトコンドリア / 虚血・再灌流障害 / ダントロレン / フォールディング / HCV / 虚血／再灌流障害 / アミノ酸 / 有機合成 / 光親和性標識 / 有機化学 / タンパク質 / 生理活性 … More Except Principal Investigator 酵素阻害剤 / 核内受容体リガンド / 生理活性物質 / プロテアーゼ / ホスホニル化反応 / 脱炭酸 / プロリン / ジペプチドイソスター / ホスホプロリン / ジペプチド / 錯体形成 / トリアゾキノリン類 / プロテアーゼ阻害剤 / ミミック / 光学分割 / 結合定数 / 阻害形式 / 酵素選択性 / バイオイソスター / 生物活性 / ホスフィン酸 / ホスホン酸 / 変異ロドプシン / 網膜色素変性症 / ニーマン・ピック病Ｃ型 / 膜タンパク質 / 蛋白質相互作用 / マルチテンプレート / 蛋白変性症 / フォールディング異常症 / トラフィッキング / PPAR / ジフェニルペンタン / 抗アンドロゲン / 肝臓X受容体 / 構造活性相関 / 生物応答調節 / 化合部物ライブラリー / ケミカルジェネティクス / 抗ウイルス剤 / ロドプシン / 構造展開 / 細胞内局在 / サリドマイド / テンプレート / 核内受容体 / フォールディング / 生物応答調節剤創製法 / 医薬分子機能学 Less

Basic pharmaceutical study of relationship between phosphorus atom introduction and non-competition of inhibitorPrincipal Investigator
- Principal Investigator
  
  Aoyama Hiroshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Tokyo University of Pharmacy and Life Science
Application of phosphate mimetics to development of biologically active compounds
- Principal Investigator
  
  Yokomatsu Tsutomu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Tokyo University of Pharmacy and Life Science
Basic medicinal chemistry based on behavioral structure-building regulation of proteinPrincipal Investigator
- Principal Investigator
  
  AOYAMA hiroshi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Tokyo University of Pharmacy and Life Science
Chemical control of protein dramatype
- Principal Investigator
  
  HASHIMOTO Yuichi
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Drug development chemistry
- Research Institution
  The University of Tokyo
Biological response modification based on multi-template and dramatype approaches.
- Principal Investigator
  
  HASHIMOTO Yuichi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  The University of Tokyo
Basic medicinal chemistry in novel biologically active compounds based on behavioral regulation of proteinPrincipal Investigator
- Principal Investigator
  
  AOYAMA Hiroshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  The University of Tokyo

All 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Patent

[Journal Article] A novel and facile route for the synthesis of medetomidine as the α2-adrenoceptor agonist2017
- Author(s)
  Kaboudin Babak、Haghighat Hamideh、Aieni Samira、Behrouzi Leila、Kazemi Foad、Kato Jun-ya、Aoyama Hiroshi、Yokomatsu Tsutomu
- Journal Title
  
  Journal of the Iranian Chemical Society
  
  Volume: 14 Issue: 8 Pages: 1735-1739
- DOI
  10.1007/s13738-017-1114-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08033
[Journal Article] Synthesis of 5-aminobenzoimidazo[1,2-a]quinoline derivatives through one-pot two-step cascade reaction2016
- Author(s)
  J. Kato, Y. Ito, R. Ijuin, H. Aoyama, and T. Yokomatsu
- Journal Title
  
  Heterocycles
  
  Volume: xx
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460155
[Journal Article] Discovery of non-competitive thrombin inhibitor derived from competitive tryptase inhibitor skeleton: Shift in molecular recognition resulted from skeletal conversion of carboxylate into phosphonate2015
- Author(s)
  Hiroshi Aoyama, Ryosuke Ijuin, Jun-ya Kato, Sarasa Urushiyama, Masashi Tetsuhashi, Yuichi Hashimoto, Tsutomu Yokomatsu
- Journal Title
  
  Bioorganic and Medicinal Chemistry Letters
  
  Volume: 25 Issue: 17 Pages: 3676-3680
- DOI
  10.1016/j.bmcl.2015.06.039
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08033, KAKENHI-PROJECT-25460155
[Journal Article] A Catalyst-free, Three-component Decarboxylative Coupling of Amino Acids with Aldehydes and H-dialkylphosphites for the Synthesis of α-Aminophosphonates2013
- Author(s)
  Babak Kaboudin, Leila Karami, Jun-ya Kato, Hiroshi Aoyama, and Tsutomu Yokomatsu
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: 54 Issue: 36 Pages: 4872-4875
- DOI
  10.1016/j.tetlet.2013.06.129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460155
[Journal Article] A Novel and Simple Method for the Preparation of (R)- and (S)-Pyrrolidine-2-phosphonic Acids: Phosphonic Acid Analogues of Proline2013
- Author(s)
  Babak Kaboudin, Jun-ya Kato, Hiroshi Aoyama, and Tsutomu Yokomatsu
- Journal Title
  
  Tetrahedron: Asymmetry
  
  Volume: 24 Issue: 24 Pages: 1562-1566
- DOI
  10.1016/j.tetasy.2013.10.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460155
[Journal Article] Novel Strategy for Synthesis of Substituted Benzimidazo[1,2-a]quinolines2013
- Author(s)
  Jun-ya Kato, Yutaro Ito, Ryosuke Ijuin, Hiroshi Aoyama, Tsutomu Yokomatsu
- Journal Title
  
  Organic Letters
  
  Volume: 15 Issue: 14 Pages: 3794-3797
- DOI
  10.1021/ol4017723
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790119, KAKENHI-PROJECT-25460147
[Journal Article] Design, synthesis, and biological evaluation of novel transrepression-selective liver X receptor (LXR) ligands with 5,11-dihydro-5-methyl-11-methylene-6H-dibenz[b,e]-azepin-6-one skeleton.2012
- Author(s)
  Atsushi Aoyama
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 55 Issue: 17 Pages: 7360-7377
- DOI
  10.1021/jm3002394
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790107, KAKENHI-PROJECT-22249006
[Journal Article] Small-molecular inhibitors of Ca2+-induced mitochondrial permeability transition (MPT) derived from muscle relaxant dantrolene.2012
- Author(s)
  Shinpei Murasawa
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 20 Issue: 21 Pages: 6384-6393
- DOI
  10.1016/j.bmc.2012.08.062
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790107, KAKENHI-PROJECT-22249006, KAKENHI-PROJECT-24790119
[Journal Article] Fused heterocyclic amide compounds as anti-hepatitis C virus agents2011
- Author(s)
  Hiroshi Aoyama, Masahiko Nakamura
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 19 Issue: 8 Pages: 2675-2687
- DOI
  10.1016/j.bmc.2011.03.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J09835, KAKENHI-PROJECT-22249006
[Journal Article] Nitrogen-containing fused-heteroaromatic compounds as a anti-bovine diarrhea virus (BVDV) agents.2010
- Author(s)
  Aoyama H, Baba M, Hashimoto Y
- Journal Title
  
  Curr. Bioactive Comp. 6(2)
  
  Pages: 118-128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390028
[Journal Article] Structural development studies of anti-hepatitis virus C virus agents2010
- Author(s)
  M.Nakamura, A.Aoyama, M.T.M.Salim, M.Okamoto, M.Baba, M.Baba, H.Miyachi, Y.Hashimoto, H.Aoyama
- Journal Title
  
  Bioorg. Med. Chem
  
  Volume: 18 Issue: 7 Pages: 2402-2411
- DOI
  10.1016/j.bmc.2010.02.057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249006
[Journal Article] Polymethylated γ-carbolines with potent anti-bovine viral diarrhea virus(BVDV)activity.2009
- Author(s)
  Hiroshi Aoyama, 他6名
- Journal Title
  
  Heterocycles 77
  
  Pages: 779-785
- NAID
  40016454317
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390028
[Journal Article] Liver X receptor(LXR)modulators with dibenz[b,f][1,4]oxazepin-11-one,(Z)-dibenz[b,f]azocin-6-one, and 11, 12-dihydrodibenz[b,f]azocin-6-one skeleton.2009
- Author(s)
  Atsushi Aoyama, 他4名
- Journal Title
  
  Heterocycles 78
  
  Pages: 2209-2216
- NAID
  40016702610
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390028
[Journal Article] Polymethylated γ-carbolines with potent anti-bovine viral diarrhea virus (BVDV) activity.2009
- Author(s)
  Hiroshi Aoyama, 他6名
- Journal Title
  
  Heterocycles 77(2)
  
  Pages: 779-785
- NAID
  40016454317
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390028
[Journal Article] Demonstration of Direct Binding of cIAP1 Degradation-promoting Bestatin Analogs to BIR3 Domain : Synthesis and Application of Fluorescent Bestatin Ester Analogs2008
- Author(s)
  Shinichi Sato, Hiroshi Aoyama, Hiroyuki Miyachi, Mikihiko Naito, Yuichi Hashimoto
- Journal Title
  
  Bioorg. Med. Chem. Lett 18
  
  Pages: 3354-3358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790007
[Journal Article] LXR antagonists with a 5-substituted phenanthridin-6-one skeleton: Synthesis and LXR transrepression activities of conformationally restricted carba-To901317 analogs.2008
- Author(s)
  Atsushi Aoyama, 他5名
- Journal Title
  
  Heterocycles 76(1)
  
  Pages: 137-142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390028
[Journal Article] Degradation-promoters of cellular inhibitor of apoptosis protein 1 based on bestatin and actinonin.2008
- Author(s)
  Sato S, Tetsuhashi M, Sekine K, Miyachi H, Naito M, Hashimoto Y, Aoyama H
- Journal Title
  
  Bioorg. Med. Chem. 16(8)
  
  Pages: 4685-4698
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390028
[Journal Article] Degradation-promoters of Cellular Inhibitor of Apoptosis Protein 1 Based on Bestatin and Actinonin2008
- Author(s)
  Shinichi Sato, Masashi Tetsuhashi, Keiko Sekine, Hiroyuki Miyachi, Mikihiko Naito, Yuichi Hashimoto, Hiroshi Aoyama
- Journal Title
  
  Bioorg. Med. Chem 16
  
  Pages: 4685-4698
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790007
[Journal Article] Demonstration of direct binding of cIAP1 degradationpromoting bestatin analogs to BIR3 domain : synthesis and application of fluorescent bestatin ester analogs2008
- Author(s)
  S. Sato, H. Aoyama et.al.
- Journal Title
  
  Bioorg. Med. Chem. Lett 18
  
  Pages: 3354-3358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790007
[Journal Article] Degradationpromoters of Cellular Inhibitor of Apoptosis Protein 1 Based on B estatin and Actinonin2008
- Author(s)
  S. Sato, H. Aoyama et.al.
- Journal Title
  
  Bioorg. Med. Chem 16
  
  Pages: 4685-4698
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790007
[Journal Article] Fusarielin A as an Anti-angiogenic and Anti-proliferative Agent : Basic Biological Characterization2008
- Author(s)
  Haruka Fujimoto, Hiroshi Aoyama, Tomomi Noguchi-Yachide, Yuichi Hashimoto, Hisayoshi Kobayashi
- Journal Title
  
  Chem. Pharm. Bull 56
  
  Pages: 298-304
- NAID
  110006622632
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790007
[Journal Article] Co-existence of alpha-glucosidase-inhibitory activity and liver X receptor-regulatory activities and their separation by structural development.2008
- Author(s)
  Dodo K, Aoyama H, Noguchi-Yachide T, Makishima M, Miyachi H, Hashimoto Y
- Journal Title
  
  Bioorg. Med. Chem. 16(8)
  
  Pages: 4272-4285
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390028
[Journal Article] Development of tubulin-polymerization inhibitors based on thalidomide skeleton2007
- Author(s)
  H. Aoyama, 他6名
- Journal Title
  
  Chelnica1 & Pharmaceutical Bullietin 55
  
  Pages: 944-949
- NAID
  110006278705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390028
[Journal Article] Development of Tubulin-polymerization Inhibitors Based on the Thalidomide Skeleton2007
- Author(s)
  Hiroshi Aoyama, Tomomi Noguchi, Takashi Misawa, Takanori Nakamura, Hiroyuki Miyachi, Yuichi Hashimoto, Hisayoshi Kobayashi
- Journal Title
  
  Chem. Pharm. Bull 55
  
  Pages: 944-949
- NAID
  110006278705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790007
[Journal Article] Development of Tubulin-Polymerization Inhibitors Based on the Thalidomide Skeleton2007
- Author(s)
  Hiroshi Aoyama
- Journal Title
  
  Chem. Phann. Bull. 55
  
  Pages: 944-949
- NAID
  110006278705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790007
[Patent] C型肝炎治療剤2010
- Inventor(s)
  馬場昌範, 橋本祐一, 青山洋史, 中村政彦, 浦田泰生
- Industrial Property Rights Holder
  国立大学法人鹿児島大学
- Industrial Property Number
  2010-020502
- Filing Date
  2010-02-01
- Data Source
  KAKENHI-PROJECT-19390028
[Patent] ジフェニルメタン誘導体を有効成分とする抗ウイルス剤2009
- Inventor(s)
  馬場昌範, 岡本実佳, 後藤志典, モハメドタハ, アーメドサリム, 橋本祐一, 青山洋史, 細田信之介
- Industrial Property Rights Holder
  国立大学法人鹿児島大学
- Filing Date
  2009-03-13
- Data Source
  KAKENHI-PROJECT-19390028
[Patent] 三環性化合物2008
- Inventor(s)
  宮地弘幸, 橋本祐一, 青山惇
- Industrial Property Rights Holder
  国立大学法人東京大学
- Industrial Property Number
  2008-050690
- Filing Date
  2008-02-29
- Data Source
  KAKENHI-PROJECT-19390028
[Patent] 新規ヒドロキサム酸誘導体2007
- Inventor(s)
  青山洋史他4名
- Industrial Property Rights Holder
  東京大学
- Industrial Property Number
  2007-266460
- Filing Date
  2007-10-12
- Overseas
- Data Source
  KAKENHI-PROJECT-19790007
[Presentation] Synthesis of a-Aminophosphonates from a;-Amino Acids by Catalyst-free Three-component Decarboxylative Coupling Reactions2014
- Author(s)
  B． Kaboudin, L． Karami, J． Kato，H．Aoyama, and T. Yokomatsu
- Organizer
  20th International Conference on Phosphorus Chemistry
- Place of Presentation
  Ｄｏｕｂｌｉｎｅ，　Ｉｒｅｌａｎｄ
- Data Source
  KAKENHI-PROJECT-25460155
[Presentation] 免疫調節作用選択的な肝臓Ｘ受容体（ＬＸＲ）リガンドの創製2012
- Author(s)
  青山惇　他９名
- Organizer
  日本レチノイド研究会第23回学術集会
- Place of Presentation
  米子（鳥取県）
- Data Source
  KAKENHI-PROJECT-22249006
[Presentation] 疫調節作用選択的な肝臓X受容体(LXR)リガンドの創製2012
- Author(s)
  青山惇、梅田(遠藤)香織、岸田健治、大金賢司、谷内出(野口)友美、青山洋史、石川稔、宮地弘幸、槇島誠、橋本祐一
- Organizer
  日本レチノイド研究会第23回学術集会
- Place of Presentation
  米子
- Data Source
  KAKENHI-PROJECT-22249006
[Presentation] Liver X Receptor (LXR)リガンドの構造展開によるTransrepression作用選択的リガンドの創製2012
- Author(s)
  青山惇, 他6名
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-22249006
[Presentation] LXRリガンドの構造展開による選択的IL-6産生抑制剤の創製2011
- Author(s)
  青山惇, 他4名
- Organizer
  日本レチノイド研究会第22回学術集会
- Place of Presentation
  東京
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PROJECT-22249006
[Presentation] LXRを介した抗炎症作用を有する選択的リガンドの創製2010
- Author(s)
  青山惇, 他6名
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-19390028
[Presentation] フタルイミド骨格を基盤としたトリプターゼ阻害剤の創製2009
- Author(s)
  鉄橋正士、橋本祐一、青山洋史
- Organizer
  第28回メディシナルケミストリーシンポジウム
- Place of Presentation
  東京
- Year and Date
  2009-11-26
- Data Source
  KAKENHI-PROJECT-19390028
[Presentation] 3,3-diindolylmethane (DIM)誘導体におけるHL-60細胞分化促進活性2009
- Author(s)
  谷内出友美、鉄橋正士、青山洋史、橋本祐一
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-19390028
[Presentation] 配座固定を基盤とした核内受容体LXRの新規リガンド創製2009
- Author(s)
  青山惇、他7名
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-19390028
[Presentation] Fusarielin Aの生物活性とその分子基盤2008
- Author(s)
  藤本悠、青山洋史、谷内出(野口)友美、橋本祐一、小林久芳
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19790007
[Presentation] タンパク質寿命制御に立脚した新規アポトーシス誘導剤創製研究2008
- Author(s)
  佐藤伸一、青山洋史、鉄橋正士、宮地弘幸、内藤幹彦、橋本祐一
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19790007
[Presentation] 配座固定を基盤とした核内受容体LXRの新規アンタゴニスト創製2008
- Author(s)
  青山惇、他7名
- Organizer
  第34回反応と合成の進歩シンポジウム
- Place of Presentation
  京都
- Year and Date
  2008-11-04
- Data Source
  KAKENHI-PROJECT-19390028
[Presentation] 配座固定を基盤とした核内受容体LXRの新規リガンド創製2008
- Author(s)
  青山惇、他7名
- Organizer
  第27回メディシナルケミストリーシンポジウム
- Place of Presentation
  大阪
- Year and Date
  2008-11-26
- Data Source
  KAKENHI-PROJECT-19390028
[Presentation] 抗BVDV活性を指標とした3環性γ-カルボリン類縁体による抗ウイルス効果2008
- Author(s)
  青山洋史、他8名
- Organizer
  第52回日本薬学会関東支部大会
- Place of Presentation
  東京
- Year and Date
  2008-10-04
- Data Source
  KAKENHI-PROJECT-19390028
[Presentation] cIAP1減少を介した新規アポトーシス誘導剤創製研究2007
- Author(s)
  佐藤伸一、青山洋史、棚谷綾、内藤幹彦、宮地弘幸、橋本祐一
- Organizer
  第26回メディシナルケミストリーシンポジウム
- Place of Presentation
  相模原
- Year and Date
  2007-11-28
- Data Source
  KAKENHI-PROJECT-19790007
[Presentation] Fusarielin Aの生物活性とその分子基盤2007
- Author(s)
  藤本悠、青山洋史、谷内出(野口)友美、橋本祐一、小林久芳
- Organizer
  第49回天然有機化合物討論会
- Place of Presentation
  札幌
- Year and Date
  2007-09-19
- Data Source
  KAKENHI-PROJECT-19790007
[Presentation] cIAP1減少を介した新規アポトーシス誘導剤の合成研究2007
- Author(s)
  佐藤伸一、青山洋史、内藤幹彦、宮地弘幸、橋本祐一、棚谷綾
- Organizer
  第33回反応と合成の進歩シンポジウム
- Place of Presentation
  長崎
- Year and Date
  2007-11-05
- Data Source
  KAKENHI-PROJECT-19790007
[Presentation] 多置換[1,2,4]トリアゾロ[1,5-a]キノリン類の新規合成法の開発
- Author(s)
  加藤淳也、成瀬央、伊集院良祐、青山洋史、横松力
- Organizer
  第44回複素環討論会
- Place of Presentation
  札幌市
- Year and Date
  2014-09-10 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25460155
[Presentation] Synthesis of a-Aminophosphonates from a-Amino Acids by Catalyst-free Three-component Decarboxylative Coupling Reactions
- Author(s)
  B. Kaboudin, L. Karami, J. Kato, H. Aoyama, and T. Yokomatsu
- Organizer
  20th International Conference on Phosphorus Chemistry
- Place of Presentation
  Dublin, Ireland
- Year and Date
  2014-06-28 – 2014-07-02
- Data Source
  KAKENHI-PROJECT-25460155

1. NOGUCHI Tomomi (20401284)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
2. HASHIMOTO Yuichi (90164798)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
3. KOBAYASHI Hisayoshi (80225531)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. ISHIKAWA Minoru (70526839)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. SUGITA Kazuyuki (60542090)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MATSUMOTO Yotaro (90420041)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MISAWA Takashi (40709820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Yokomatsu Tsutomu (70158369)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
9. 伊集院良祐 (40442925)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. KABOUDIN Babak

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results

Aoyama Hiroshi 青山 洋史

AOYAMA Hiroshi 青山 洋史

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Basic pharmaceutical study of relationship between phosphorus atom introduction and non-competition of inhibitorPrincipal Investigator

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Application of phosphate mimetics to development of biologically active compounds

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Basic medicinal chemistry based on behavioral structure-building regulation of proteinPrincipal Investigator

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Chemical control of protein dramatype

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Biological response modification based on multi-template and dramatype approaches.

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Basic medicinal chemistry in novel biologically active compounds based on behavioral regulation of proteinPrincipal Investigator

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[Journal Article] A novel and facile route for the synthesis of medetomidine as the α2-adrenoceptor agonist2017

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[Journal Article] Synthesis of 5-aminobenzoimidazo[1,2-a]quinoline derivatives through one-pot two-step cascade reaction2016

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[Journal Article] Discovery of non-competitive thrombin inhibitor derived from competitive tryptase inhibitor skeleton: Shift in molecular recognition resulted from skeletal conversion of carboxylate into phosphonate2015

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[Journal Article] A Catalyst-free, Three-component Decarboxylative Coupling of Amino Acids with Aldehydes and H-dialkylphosphites for the Synthesis of α-Aminophosphonates2013

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[Journal Article] A Novel and Simple Method for the Preparation of (R)- and (S)-Pyrrolidine-2-phosphonic Acids: Phosphonic Acid Analogues of Proline2013

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[Journal Article] Novel Strategy for Synthesis of Substituted Benzimidazo[1,2-a]quinolines2013

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[Journal Article] Design, synthesis, and biological evaluation of novel transrepression-selective liver X receptor (LXR) ligands with 5,11-dihydro-5-methyl-11-methylene-6H-dibenz[b,e]-azepin-6-one skeleton.2012

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[Journal Article] Small-molecular inhibitors of Ca2+-induced mitochondrial permeability transition (MPT) derived from muscle relaxant dantrolene.2012

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Aoyama Hiroshi 青山洋史

AOYAMA Hiroshi 青山洋史