MATSUMOTO Yotato 松本洋太郎

… Alternative Names

Researcher Number	90420041
Other IDs
Affiliation (Current)	2019: 東北大学, 薬学研究科, 講師
Affiliation (based on the past Project Information) *help	2016 – 2019: 東北大学, 薬学研究科, 講師 2017: 東北大学, 大学院薬学研究科, 講師 2013: 帝京大学, 薬学部, 講師 2012 – 2013: 東京大学, 分子細胞生物学研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Chemical pharmacy Except Principal Investigator Tumor diagnostics / Basic Section 50020:Tumor diagnostics and therapeutics-related / Drug development chemistry / Medical pharmacy / Medical Physics and Radiological Technology
Keywords	Principal Investigator ニコチンアミドアデニンジヌクレオチド / サイクリックADPリボース / 量子化学計算 / 安定同位体 / 位置選択性 / 芳香族求核置換反応 / ターゲットメタボロミクス / 構造最適化 / 反応機構解析 / 遷移構造 … More Except Principal Investigator メタボロミクス / 変異ロドプシン / 膜タンパク質 / CD73 / フォールディング異常症 / 酵素阻害剤 / 蛋白質相互作用 / 修飾核酸 / 網膜色素変性症 / 免疫制御 / トラフィッキング / がん免疫 / LC/MS / がん細胞 / 放射線耐性 / マルチテンプレート / 生理活性物質 / ＣＤ３９ / ニーマン・ピック病Ｃ型 / ＣＤ７３ / 蛋白変性症 / 核内受容体リガンド / プロテオミクス / アデノシン / 脂肪酸合成酵素 / 腫瘍マーカー Less

CD39ーCD73－アデノシンカスケードを制御する分子の探索と創薬への展開Ongoing
- Principal Investigator
  
  富岡佳久
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Tohoku University
NAD関連代謝物の包括的評価を目指したcADPRの高感度定量系の構築Principal InvestigatorOngoing
- Principal Investigator
  
  松本洋太郎
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Tohoku University
修飾核酸を標的とした新規がん免疫病態診断マーカー探索と個別化がん免疫療法への応用Ongoing
- Principal Investigator
  
  TOMIOKA Yoshihisa
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Tohoku University
Elucidation of the mechanism of radioresistance in cancer cells using trans-omics approach and development of clinical biomarkers for radiotherapy.
- Principal Investigator
  
  Kanemitsu Yoshitomi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
  Medical Physics and Radiological Technology
- Research Institution
  Tohoku University
A Theoretical Study of p-Deficient System Aromatic Nucleophlic Substitution (SNAr)Principal Investigator
- Principal Investigator
  
  MATSUMOTO Yotaro
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Teikyo University
  The University of Tokyo
Chemical control of protein dramatype
- Principal Investigator
  
  HASHIMOTO Yuichi
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Drug development chemistry
- Research Institution
  The University of Tokyo

All 2018 2017 2014 2013 2012

All Journal Article Presentation

[Journal Article] The Disease-modifying Drug Candidate, SAK3 Improves Cognitive Impairment and Inhibits Amyloid beta Deposition in App Knock-in Mice2018
- Author(s)
  Izumi H, Shinoda Y, Saito T, Saido TC, Sato K, Yabuki Y, Matsumoto Y, Kanemitsu Y, Tomioka Y, Abolhassani N, Nakabeppu Y, Fukunaga K.
- Journal Title
  
  Neuroscience
  
  Volume: 377 Pages: 87-97
- DOI
  10.1016/j.neuroscience.2018.02.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15456, KAKENHI-PROJECT-17H01391, KAKENHI-PROJECT-16J02855, KAKENHI-PROJECT-16K20909
[Journal Article] Evaluation of the impact of gut microbiota on uremic solute accumulation by a CE-TOFMS?based metabolomics approach2017
- Author(s)
  †Mishima, E., †Fukuda, S. (†equally contributed), Mukawa, C., Yuri, A., Kanemitsu, Y., Matsumoto, Y., Akiyama, Y., Fukuda, NN., Tsukamoto, H., Asaji, K., Shima, H., Kikuchi, K., Suzuki, T., Tomioka, Y., Soga, T., Ito, S., Abe, T.
- Journal Title
  
  Kidney international
  
  Volume: 92 Pages: 634-645
- DOI
  10.1016/j.kint.2017.02.011
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H04901, KAKENHI-PROJECT-16K19474, KAKENHI-PROJECT-16K20909
[Journal Article] An inhibitory epitope of human Toll-like receptor 4 resides on leucine-rich repeat 13 and is recognized by a monoclonal antibody2017
- Author(s)
  Tsukamoto Hiroki、Yamagata Yuki、Ukai Ippo、Takeuchi Shino、Okubo Misaki、Kobayashi Yohei、Kozakai Sao、Kubota Kanae、Mumasaki Muneo、Kanemitsu Yoshitomi、Matsumoto Yotaro、Tomioka Yoshihisa
- Journal Title
  
  FEBS Letters
  
  Volume: 591 Pages: 2406-2416
- DOI
  10.1002/1873-3468.12768
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K20909
[Journal Article] Simultaneous quantitative analysis of uremic toxins by LC-MS/MS with a reversed-phase/cation-exchange/anion-exchange tri-modal mixed-mode column2017
- Author(s)
  Kanemitsu Yoshitomi、Asaji Kei、Matsumoto Yotaro、Tsukamoto Hiroki、Saigusa Daisuke、Mukawa Chikahisa、Tachikawa Tatsuki、Abe Takaaki、Tomioka Yoshihisa
- Journal Title
  
  Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences
  
  Volume: 1068-1069 Pages: 1-8
- DOI
  10.1016/j.jchromb.2017.10.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K20909
[Journal Article] Rapid and selective simultaneous quantitative analysis of modified nucleosides using multi-column liquid chromatography-tandem mass spectrometry2017
- Author(s)
  4.Jinno D, Kanemitsu Y, Saitoh K, Nankumo S, Tsukamoto H, Matsumoto Y, Abe T, Tomioka Y
- Journal Title
  
  J Anal Sci Technol
  
  Volume: 8 Pages: 1-9
- DOI
  10.1186/s40543-017-0110-4
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H04704, KAKENHI-PROJECT-26460058
[Journal Article] Design and synthesis of silicon-containing steroid sulfatase inhibitors possessing pro-estrogen antagonistic character2014
- Author(s)
  Daisuke Kajita　他４名
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 22 Pages: 2244-2252
- DOI
  10.1016/j.bmc.2014.02.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249006, KAKENHI-PROJECT-24790004
[Journal Article] Development of novel silicon-containing inverse agonists of retinoic acid receptor-related orphan receptors2014
- Author(s)
  Hirozumi Toyama　他５名
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 22 Pages: 1948-1959
- DOI
  10.1016/j.bmc.2014.01.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249006, KAKENHI-PROJECT-24790004
[Journal Article] Organosilicon Compounds as Adult T-Cell Leukemia Cell Proliferation Inhibitors2013
- Author(s)
  Nakamura, M., Matsumoto, Y., Toyama, M., Baba, M. and Hashimoto, Y.
- Journal Title
  
  Chem. Pharm. Bull.
  
  Volume: 61 Issue: 2 Pages: 237-241
- DOI
  10.1248/cpb.c12-00839
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790004
[Journal Article] Amidocuprates for directed ortho cupration: structural study, mechanistic investigation, and chemical requirements.2012
- Author(s)
  Shinsuke Komagawa
- Journal Title
  
  Angew Chem Int Ed Engl.
  
  Volume: 51 Pages: 12081-12085
- DOI
  10.1002/anie.201204923
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J01857, KAKENHI-PROJECT-24790004
[Journal Article] Specific inhibitors of puromycin-sensitive aminopeptidase with a 3- (halogenated phenyl)-2,4(1H,3H)-quinazolinedione skeleton.2012
- Author(s)
  Matsumoto, Y., Noguchi-Yachide, T., Nakamura, M., Mita, Y., Numadate, A. and Hashimoto, Y.
- Journal Title
  
  Heterocycles
  
  Volume: 86 Pages: 1449-1463
- DOI
  10.3987/com-12-s(n)109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J10146, KAKENHI-PROJECT-21790107, KAKENHI-PROJECT-22249006, KAKENHI-PROJECT-24790004
[Presentation] 多層オミクス手法による放射線耐性化関連分子の探索2018
- Author(s)
  富岡佳久、金光祥臣、松本洋太郎、桑原義和、福本　学、塚本宏樹
- Organizer
  第3回治療耐性がん細胞研究協議会セミナー
- Data Source
  KAKENHI-PROJECT-16K20909
[Presentation] LC-HDMS および IMS を用いたヒト肝癌組織メタボロミクスによる新規バイオマーカーの同定2017
- Author(s)
  永井滉士、三枝大輔、山崎貴広、金光祥臣、塚本宏樹、池田均、矢冨裕、松本洋太郎、富岡佳久
- Organizer
  第56回日本薬学会東北支部大会
- Data Source
  KAKENHI-PROJECT-16K20909
[Presentation] ミックスドモード ODS カラムを用いた LC-MS/MS による尿毒症物質一斉定量系の構築2017
- Author(s)
  金光祥臣、淺地圭、松本洋太郎、塚本宏樹、三枝大輔、阿部高明、富岡佳久
- Organizer
  第56回日本薬学会東北支部大会
- Data Source
  KAKENHI-PROJECT-16K20909
[Presentation] 膠芽腫幹細胞を標的とした sirtuin2 阻害剤の創製研究2014
- Author(s)
  境　太希，若井　信彦，松本　洋太郎，林　寛敦，石川　稔，杉田　和幸，北尾　彰朗，秋山　徹，橋本　祐一
- Organizer
  日本薬学会第134回年会（熊本）
- Place of Presentation
  熊本市総合体育館
- Data Source
  KAKENHI-PROJECT-24790004
[Presentation] 膠芽腫幹細胞を標的としたsirtuin2 阻害剤の創製研究2014
- Author(s)
  境太希、若井信彦、松本洋太郎、林寛敦、石川稔、杉田和幸、北尾彰朗、秋山徹、橋本祐一
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-22249006
[Presentation] 新規 ROR 転写抑制リガンドの創製とケイ素導入による活性の向上2014
- Author(s)
  外山　大純，中村　雅陽，中村　政彦，松本　洋太郎，中込　まどか，橋本　祐一
- Organizer
  日本薬学会第134回年会（熊本）
- Place of Presentation
  熊本市総合体育館
- Data Source
  KAKENHI-PROJECT-24790004
[Presentation] 含ケイ素抗エストロゲン様活性物質の創製2014
- Author(s)
  梶田　大資，中村　雅陽，松本　洋太郎，橋本　祐一
- Organizer
  日本薬学会第134回年会（熊本）
- Place of Presentation
  熊本市総合体育館
- Data Source
  KAKENHI-PROJECT-24790004
[Presentation] サリドマイド由来エストロゲン受容体リガンドの創製2012
- Author(s)
  谷内出友美、杉田和幸、松本洋太郎、橋本祐一
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22249006

1. TOMIOKA Yoshihisa (00282062)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
2. TSUKAMOTO Hiroki (70423605)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
3. HASHIMOTO Yuichi (90164798)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. ISHIKAWA Minoru (70526839)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. AOYAMA Hiroshi (40374699)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SUGITA Kazuyuki (60542090)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. KOBAYASHI Hisayoshi (80225531)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. YACHIDE Tomomi (20401284)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. MISAWA Takashi (40709820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. Kanemitsu Yoshitomi (30752943)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
11. FUKUMOTO Manabu (60156809)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. KUWAHARA Yoshikazu (00392225)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 福田真嗣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 三島英換

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 矢吹悌

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 中別府雄作

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MATSUMOTO Yotato 松本 洋太郎

MATSUMOTO Yotaro 松本 洋太郎

Research Projects

Research Products

Co-Researchers

CD39ーCD73－アデノシンカスケードを制御する分子の探索と創薬への展開Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

NAD関連代謝物の包括的評価を目指したcADPRの高感度定量系の構築Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

修飾核酸を標的とした新規がん免疫病態診断マーカー探索と個別化がん免疫療法への応用Ongoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the mechanism of radioresistance in cancer cells using trans-omics approach and development of clinical biomarkers for radiotherapy.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A Theoretical Study of p-Deficient System Aromatic Nucleophlic Substitution (SNAr)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Chemical control of protein dramatype

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The Disease-modifying Drug Candidate, SAK3 Improves Cognitive Impairment and Inhibits Amyloid beta Deposition in App Knock-in Mice2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evaluation of the impact of gut microbiota on uremic solute accumulation by a CE-TOFMS?based metabolomics approach2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] An inhibitory epitope of human Toll-like receptor 4 resides on leucine-rich repeat 13 and is recognized by a monoclonal antibody2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Simultaneous quantitative analysis of uremic toxins by LC-MS/MS with a reversed-phase/cation-exchange/anion-exchange tri-modal mixed-mode column2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Rapid and selective simultaneous quantitative analysis of modified nucleosides using multi-column liquid chromatography-tandem mass spectrometry2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Design and synthesis of silicon-containing steroid sulfatase inhibitors possessing pro-estrogen antagonistic character2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of novel silicon-containing inverse agonists of retinoic acid receptor-related orphan receptors2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Organosilicon Compounds as Adult T-Cell Leukemia Cell Proliferation Inhibitors2013

Author(s)

Journal Title

DOI

MATSUMOTO Yotato 松本洋太郎

MATSUMOTO Yotaro 松本洋太郎