MIZUMOTO Shuji 水本秀二

Researcher Number	40443973
Other IDs	https://orcid.org/0000-0002-4641-1505
External Links
Affiliation (Current)	2025: 名城大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 名城大学, 薬学部, 准教授 2013 – 2018: 名城大学, 薬学部, 助教 2012: 北海道大学, 大学院・先端生命科学研究院, 博士研究員 2011 – 2012: 北海道大学, 先端生命科学研究科(研究院), 博士研究員 2010: 北海道大学, 大学院・先端生命科学研究院, 学術研究員
Review Section/Research Field	Principal Investigator Biological pharmacy / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related Except Principal Investigator Biological pharmacy / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Basic Section 53050:Dermatology-related / Basic Section 42020:Veterinary medical science-related / Basic Section 52050:Embryonic medicine and pediatrics-related
Keywords	Principal Investigator プロテオグリカン / グリコサミノグリカン / コンドロイチン硫酸 / 遺伝病 / デルマタン硫酸 / ノックアウトマウス / エーラス・ダンロス症候群 / ヘパラン硫酸 / ヌクレオチダーゼ / 糖転移酵素 … More / UDP / CANT1 / CSGALNACT1 / B3GAT3 / ゼブラフィッシュ / B3GALT6 / RNA-seq / CHST14 / 偽性捻曲性骨異形成症 / 前頭骨幹端異形成症 / 耳口蓋指症候群 / 粘液腫性心臓弁膜ジストロフィー / フィラミン / 遺伝性骨・皮膚疾患 / ゴルジ体 / ゴルジン / 皮膚弛緩症 / 骨系統疾患 / 脊椎肋骨異骨症 / 結合組織疾患 / LFNG / 免疫不全症 / 骨異形成性老人性皮膚症 / 脊椎骨端骨幹端異形成症 / GORAB / Golgin / 糖尿病 / てんかん / 老化 / 骨・皮膚疾患 / アルツハイマー病 / 癌 / RAGE / ニュージーランド / ドイツ / 変形性関節症 / 骨形成 / ダンロス症候群/糖転移酵素/硫酸基転移酵素 / 皮膚/遺伝病/脊椎骨端異形成症/ エーラス / コンドロイチン硫酸/デルマタン硫酸/骨 … More Except Principal Investigator コンドロイチン硫酸 / グリコサミノグリカン / ヘパラン硫酸 / デルマタン硫酸 / 筋拘縮型エーラス・ダンロス症候群 / 癌 / プロテオグリカン / ノックアウトマウス / 生合成 / Chst14遺伝子欠損マウス / 筋拘縮型エーラス・ダンロス症候群(mcEDS) / 疾患モデル動物 / ヒアルロン酸 / ヒアルロニダーゼ / オリゴ糖 / RAGE / 転移 / 加水分解酵素 / 遺伝病 / 創傷治癒 / マルチオミクス / 遺伝性疾患 / ゲノム編集 / 骨系統疾患 / 軟骨 / 遺伝子欠損マウス / 糖ヌクレオチド輸送体 / キシロース転移酵素 / EXTL3 / 糖転移酵素 / へパラン硫酸 / 包括的病態解析 / iPS細胞 / マウスモデル / 皮膚病変 / 筋拘縮型エーラスダンロス症候群(mcEDS) / エーラスダンロス症候群 / エーラス・ダンロス症候群 / Chst14 / 糖尿病 / 老化 / アルツハイマー病 / 低分子化合物 / 糖鎖創薬 / 基質特異性 / プロテオミクス / ルイス肺癌細胞 / 計科学 / 肝再生 / basic FGF / 肝細胞増殖因子 / プレイオトロフィン / 増殖因子 / 単クローン抗体 / 脳 / デルマタン硫酸エピメラーゼ / 計算科学 / 細胞増殖因子 / 神経突起 Less

糖ヌクレオチド輸送体が司る骨格形成メカニズムの解明
- Principal Investigator
  
  古市達哉
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Iwate University
Biochemical and multi-omics analysis of hereditary disorders caused by deficiency of glycosaminoglycan biosynthesis
- Principal Investigator
  
  山田修平
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Meijo University
Pathogenic mechanisms of hereditary neurological, immune, skeletal disorders caused by mutations in UDP metabolic enzymePrincipal Investigator
- Principal Investigator
  
  水本秀二
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Meijo University
筋拘縮型エーラス・ダンロス症候群の創傷治癒過程におけるデルマタン硫酸の役割
- Principal Investigator
  
  吉沢隆浩
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Shinshu University
Elucidation of the pathogenetic mechanisms of congenital diseases caused by the mutations in biosynthetic enzymes of heparan sulfate
- Principal Investigator
  
  Yamada Shuhei
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Meijo University
Crosstalk of proteoglycan and filamin and their genetic disordersPrincipal Investigator
- Principal Investigator
  
  Shuji Mizumoto
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Meijo University
Development and analysis of an animal model of Musculocontractral Ehlers-Danlos syndrome
- Principal Investigator
  
  Yoshizawa Takahiro
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Shinshu University
Integrated understanding of dermatan sulfate through uncovering pathophysiology of musculocontractural Ehlers-Danlos syndrome
- Principal Investigator
  
  Kosho Tomoki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Shinshu University
Mechanism of biosynthesis of glycosaminoglycan by Golgin, and its hereditary bone and skin disordersPrincipal Investigator
- Principal Investigator
  
  Mizumoto Shuji
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Meijo University
Function as well as regulation on expression of a novel hyaluronidase in cancer and inflammation
- Principal Investigator
  
  Yamada Shuhei
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Meijo University
Drug discovery of innovative small molecules with inhibition of RAGE-GAG interaction
- Principal Investigator
  
  KAZUYUKI Sugahara
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
Roles of chondroitin sulfate interacting with RAGE involved in tumor and Alzheimer's diseasePrincipal Investigator
- Principal Investigator
  
  Shiji Mizumoto
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Meijo University
Structural and functional studies on the novel hyaluronidase trying for its clinical application
- Principal Investigator
  
  YAMADA Shuhei
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Meijo University
Molecular mechanism for roles of chondroitin sulfate in tumor metastasis
- Principal Investigator
  
  SUGAHARA Kazuyuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
Pathogenic mechanisms of the bone diseases caused by defect in chondroitin sulfate biosynthesisPrincipal Investigator
- Principal Investigator
  
  MIZUMOTO Shuji
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
Molecular mechanism of proteoglycan signalings
- Principal Investigator
  
  SUGAHARA Kazuyuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University

[Book] 糖鎖生物学 (生命現象と糖鎖情報)2020
- Author(s)
  水本秀二、山田修平
- Total Pages
  306
- Publisher
  名古屋大学出版会
- Data Source
  KAKENHI-PROJECT-19H03616
[Book] コラム11：プロテオグリカンと病気、pp. 268-272、「糖鎖生物学 (生命現象と糖鎖情報)」、編集：北島健、佐藤ちひろ、門松健治、加藤晃一2020
- Author(s)
  水本秀二、山田修平
- Total Pages
  296
- Publisher
  名古屋大学出版会
- ISBN
  9784815809812
- Data Source
  KAKENHI-PROJECT-19K07054
[Book] Encyclopedia of Polymeric Nanomaterials2015
- Author(s)
  Kazuyuki Sugahara, Shuji Mizumoto, Shuhei Yamada
- Total Pages
  2500
- Publisher
  Springer-Verlag
- Data Source
  KAKENHI-PROJECT-25860037
[Book] Encyclopedia of Polymeric Nanomaterials2015
- Author(s)
  Kazuyuki Sugahara, Shuji Mizumoto, and Shuhei Yamada
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-24590071
[Book] ヘパラン硫酸 In 糖鎖の新機能開発・応用ハンドブック～創薬・医療からヘルスケアまで～2015
- Author(s)
  水本秀二、菅原一幸
- Publisher
  エヌ・ティー・エス
- Data Source
  KAKENHI-PROJECT-25860037
[Book] Encyclopedia of Polymeric Nanomaterials2015
- Author(s)
  Kazuyuki Sugahara, Shuji Mizumoto, and Shuhei Yamada
- Total Pages
  2672
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-15K07951
[Book] Chondroitin Sulfate In Encyclopedia of Polymeric Nanomaterials2015
- Author(s)
  Kazuyuki Sugahara, Shuji Mizumoto, Shuhei Yamada
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-25860037
[Book] グリコサミノグリカン・プロテオグリカンの分解 In 糖鎖の新機能開発・応用ハンドブック～創薬・医療からヘルスケアまで～2015
- Author(s)
  山田修平、水本秀二、菅原一幸
- Publisher
  エヌ・ティー・エス
- Data Source
  KAKENHI-PROJECT-25860037
[Book] Carbohydrate (N-acetyl-D-galactosamine 4-O) sulfotransferase 14 (CHST14) In Handbook of Glycosyltransferases and Related Gene2014
- Author(s)
  Tomoki Kosho, Shuji Mizumoto, Kazuyuki Sugahara
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-25860037
[Book] 「ISCSM2011 Chondroitin sulfate E-type structure at tumor cell surface is involved in experimental metastasis (Chapter 3)」, Advances in Experimental Medicine and Biology "Biochemical Roles of Eukaryotic Cell Surface Macromolecules", (P. R. Sudhakaran and A. Surolia, eds)2012
- Author(s)
  Kazuyuki Sugahara, Shuji Mizumoto
- Publisher
  Springer, New York
- Data Source
  KAKENHI-PROJECT-23390016
[Book] 「Bone and Skin Disorders Caused by a Disturbance in the Bioynthesis of Chondroitin Sulfate and Dermatan Sulfate 」, Extracellular matrix : Pathobiology and signaling , (N. Karamanos ed.)2012
- Author(s)
  Shuji Mizumoto, Kazuyuki Sugahara
- Publisher
  Walter De Gruyter, Berlin, Germany
- Data Source
  KAKENHI-PROJECT-23390016
[Book] Bone and Skin Disorders Caused by a Disturbance in the Bioynthesis of Chondroitin Sulfate and Dermatan Sulfate in Extracellular matrix: Pathobiology and signaling2012
- Author(s)
  Shuji MIZUMOTO and Kazuyuki SUGAHARA
- Publisher
  Walter De Gruyter, Berlin, Germany
- Data Source
  KAKENHI-PROJECT-23790066
[Book] Walter De Gruyter, Berlin, Germany2012
- Author(s)
  Shuji MIZUMOTO and Kazuyuki SUGAHARA、Bone and Skin Disorders Caused by a Disturbance in the Bioynthesis of Chondroitin Sulfate and Dermatan Sulfate
- Publisher
  Extracellular matrix: Pathobiology and signaling, (N. Karamanos ed.)
- Data Source
  KAKENHI-PROJECT-23790066
[Journal Article] Collagen Network Formation in In Vitro Models of Musculocontractural Ehlers Danlos Syndrome2023
- Author(s)
  Ayana Hashimoto, Takuya Hirose, Kohei Hashimoto, Shuji Mizumoto, Yuko Nitahara-Kasahara, Shota Saka, Takahiro Yoshizawa, Takashi Okada, Shuhei Yamada, Tomoki Kosh, Takafumi Watanabe, Shinji Miyata, and Yoshihiro Nomura
- Journal Title
  
  Genes
  
  Volume: 14 Issue: 2 Pages: 308-308
- DOI
  10.3390/genes14020308
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K05508, KAKENHI-PROJECT-19K08745, KAKENHI-PROJECT-22K06921
[Journal Article] Mice lacking nucleotide sugar transporter SLC35A3 exhibit lethal chondrodysplasia with vertebral anomalies and impaired glycosaminoglycan biosynthesis2023
- Author(s)
  Saito S, Mizumoto S, Yonekura T, Yamashita R, Nakano K, Okubo T, Yamada S, Okamura T, Furuichi T.
- Journal Title
  
  PLoS One
  
  Volume: 18 Issue: 4 Pages: e0284292-e0284292
- DOI
  10.1371/journal.pone.0284292
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K05932, KAKENHI-PROJECT-23K06142, KAKENHI-PROJECT-21K06552
[Journal Article] Myopathy associated with dermatan sulfate-deficient decorin and myostatin in musculocontractural Ehlers-Danlos syndrome: a mouse model investigation2021
- Author(s)
  Yuko Nitahara-Kasahara, Guillermo Posadas-Herrera, Shuji Mizumoto, Aki Nakamura-Takahashi, Yukiko U. Inoue, Takayoshi Inoue, Yoshihiro Nomura, Shin’ichi Takeda, Shuhei Yamada, Tomoki Kosho, Takashi Okada
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 9 Pages: 695021-695021
- DOI
  10.3389/fcell.2021.695021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07054, KAKENHI-PUBLICLY-19H04922, KAKENHI-PROJECT-19H03616, KAKENHI-PROJECT-20K06467
[Journal Article] A new mouse model of Ehlers-Danlos syndrome generated using CRISPR/Cas9-mediated genomic editing.2021
- Author(s)
  Yuko Nitahara-Kasahara, Shuji Mizumoto, et al.
- Journal Title
  
  Disease Models & Mechanisms
  
  Volume: 14 Issue: 12
- DOI
  10.1242/dmm.048963
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07054, KAKENHI-PUBLICLY-19H04922, KAKENHI-PROJECT-19H03616, KAKENHI-PROJECT-19K08745, KAKENHI-PROJECT-20K06467
[Journal Article] Systematic investigation of the skin in Chst14－/－ mice: a model for skin fragility in musculocontractural Ehlers-Danlos syndrome caused by CHST14 variants (mcEDS-CHST14)2021
- Author(s)
  Takuya Hirose*, Shuji Mizumoto*, Ayana Hashimoto, Yuki Takahashi, Takahiro Yoshizawa, Yuko Nitahara-Kasahara, Naoki Takahashi, Jun Nakayama, Kazushige Takehana, Takashi Okada, Yoshihiro Nomura, Shuhei Yamada, Tomoki Kosho, Takafumi Watanabe (*equal contribution)
- Journal Title
  
  Glycobiology
  
  Volume: 31 Issue: 2 Pages: 137-150
- DOI
  10.1093/glycob/cwaa058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07054, KAKENHI-PROJECT-19K08745, KAKENHI-PROJECT-19H03616
[Journal Article] An Overview of in vivo Functions of Chondroitin Sulfate and Dermatan Sulfate Revealed by Their Deficient Mice2021
- Author(s)
  Shuji Mizumoto, Shuhei Yamada
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 9 Pages: 764781-764781
- DOI
  10.3389/fcell.2021.764781
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07054, KAKENHI-PROJECT-19H03616
[Journal Article] Congenital Disorders of Deficiency in Glycosaminoglycan Biosynthesis2021
- Author(s)
  Shuji Mizumoto, Shuhei Yamada
- Journal Title
  
  Frontiers in Genetics
  
  Volume: 12 Pages: 717535-717535
- DOI
  10.3389/fgene.2021.717535
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07054, KAKENHI-PROJECT-19H03616, KAKENHI-PROJECT-21K06552
[Journal Article] Novel insight into glycosaminoglycan biosynthesis based on gene expression profiles2021
- Author(s)
  Yi-Fan Huang, Shuji Mizumoto, Morihisa Fujita
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 9 Pages: 709018-709018
- DOI
  10.3389/fcell.2021.709018
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07054
[Journal Article] Memories of Professor Kazuyuki Sugahara2021
- Author(s)
  Shuji Mizumoto
- Journal Title
  
  Trends in Glycoscience and Glycotechnology
  
  Volume: 33 Issue: 192 Pages: E49-E50
- DOI
  10.4052/tigg.2102.7E
- NAID
  130008002900
- ISSN
  0915-7352, 1883-2113
- Year and Date
  2021-03-25
- Language
  English
- Open Access
- Data Source
  KAKENHI-PROJECT-19K07054
[Journal Article] CSGALNACT1-congenital disorder of glycosylation: A mild skeletal dysplasia with advanced bone age2020
- Author(s)
  Shuji Mizumoto, Andreas R. Janecke, Azita Sadeghpour, Gundula Povysil, Marie T. McDonald, Sheila Unger, Susanne Greber-Platzer, Kristen L. Deak, Task Force for Neonatal Genomics, Nicholas Katsanis, Andrea Superti-Furga, Erica E. Davis, Shuhei Yamada, Julia Vodopiutz
- Journal Title
  
  Human Mutation
  
  Volume: 41 Issue: 3 Pages: 655-667
- DOI
  10.1002/humu.23952
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07054
[Journal Article] Delineation of musculocontractural Ehlers?Danlos Syndrome caused by dermatan sulfate epimerase deficiency2020
- Author(s)
  Lautrup Charlotte K.、Teik Keng W.、Unzaki Ai、Mizumoto Shuji、Syx Delfien、Sin Heng H.、Nielsen Irene K.、Markholt Sara、Yamada Shuhei、Malfait Fransiska、Matsumoto Naomichi、Miyake Noriko、Kosho Tomoki
- Journal Title
  
  Molecular Genetics & Genomic Medicine
  
  Volume: 8 Issue: 5
- DOI
  10.1002/mgg3.1197
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-19H03616, KAKENHI-PROJECT-19H03621, KAKENHI-PROJECT-19K07054
[Journal Article] b3galt6 knock-out zebrafish recapitulate β3GalT6-deficiency disorders in human and reveal a trisaccharide proteoglycan linkage region2020
- Author(s)
  Sarah Delbaere, Adelbert De Clercq, Shuji Mizumoto, Fredrik Noborn, Jan Willem Bek, Lien Alluyn, Charlotte Gistelinck, Delfien Syx, Phil L. Salmon, Paul J. Coucke, Goran Larson, Shuhei Yamada, Andy Willaert, Fransiska Malfait
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 8 Pages: 597857-597857
- DOI
  10.3389/fcell.2020.597857
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07054
[Journal Article] Congenital Disorders Caused by Defects in Anabolism of Glycosaminoglycans2020
- Author(s)
  Shuji Mizumoto, Shuhei Yamada
- Journal Title
  
  Trends in Glycoscience and Glycotechnology
  
  Volume: 32 Issue: 186 Pages: E45-E51
- DOI
  10.4052/tigg.1759.1E
- NAID
  130007815517
- ISSN
  0915-7352, 1883-2113
- Year and Date
  2020-03-25
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07054, KAKENHI-PROJECT-19H03616, KAKENHI-PROJECT-18K06670
[Journal Article] Congenital Disorders Caused by Defects in Catabolism of Glycosaminoglycans2020
- Author(s)
  Shuhei Yamada, Shuji Mizumoto
- Journal Title
  
  Trends in Glycoscience and Glycotechnology
  
  Volume: 32 Issue: 188 Pages: E127-E133
- DOI
  10.4052/tigg.1968.1E
- NAID
  130007879857
- ISSN
  0915-7352, 1883-2113
- Year and Date
  2020-07-25
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07054, KAKENHI-PROJECT-19H03616, KAKENHI-PROJECT-18K06670
[Journal Article] Pseudodiastrophic dysplasia expands the known phenotypic spectrum of defects in proteoglycan biosynthesis2020
- Author(s)
  Alicia B. Byrne, Shuji Mizumoto, Peer Arts, Patrick Yap, Jinghua Feng, Andreas W. Schreiber, Milena Babic, Sarah L. King-Smith, Christopher P. Barnett, Lynette Moore, Kazuyuki Sugahara, Hatice Mutlu-Albayrak, Gen Nishimura, Jan E. Liebelt, Shuhei Yamada, Ravi Savarirayan, Hamish S. Scott
- Journal Title
  
  Journal of Medical Genetics
  
  Volume: 57 Issue: 7 Pages: 454-460
- DOI
  10.1136/jmedgenet-2019-106700
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07054
[Journal Article] Recent Advances in the Pathophysiology of Musculocontractural Ehlers-Danlos Syndrome2019
- Author(s)
  Tomoki Kosho, Shuji Mizumoto, Takafumi Watanabe, Takahiro Yoshizawa, Noriko Miyake, Shuhei Yamada
- Journal Title
  
  Genes
  
  Volume: 11 Issue: 1 Pages: 43-43
- DOI
  10.3390/genes11010043
- NAID
  120006901092
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07054, KAKENHI-PROJECT-19K08745, KAKENHI-PROJECT-19H03616, KAKENHI-PROJECT-16K19396
[Journal Article] Functional Analysis of Dermatan Sulfate and Chondroitin Sulfate2019
- Author(s)
  Shuji Mizumoto
- Journal Title
  
  Trends in Glycoscience and Glycotechnology
  
  Volume: 31 Issue: 181 Pages: SE98-SE99
- DOI
  10.4052/tigg.1946.2SE
- NAID
  130007683650
- ISSN
  0915-7352, 1883-2113
- Year and Date
  2019-07-25
- Language
  English
- Data Source
  KAKENHI-PROJECT-19K07054
[Journal Article] コンドロイチン/デルマタン硫酸の生合成不全による遺伝性の骨・皮膚疾患と肺がん転移の分子メカニズム2019
- Author(s)
  水本秀二
- Journal Title
  
  薬学雑誌
  
  Volume: 139 Pages: 1495-1500
- NAID
  130007754062
- Data Source
  KAKENHI-PROJECT-19H03616
[Journal Article] Hyaluronidase-4 is produced by mast cells and can cleave serglycin chondroitin sulfate chains into lower molecular weight forms2019
- Author(s)
  Brooke L. Farrugia, Shuji Mizumoto, Megan S. Lord, Robert L. O’Grady, Rhiannon P. Kuchel, Shuhei Yamada, John M. Whitelock
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 294 Issue: 30 Pages: 11458-11472
- DOI
  10.1074/jbc.ra119.008647
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07054
[Journal Article] Structural alteration of glycosaminoglycan side chains and spatial disorganization of collagen networks in the skin of patients with mcEDS-CHST142019
- Author(s)
  Takuya Hirose, Naoki Takahashi, Prasarn Tangkawattana, Jun Minaguchi, Shuji Mizumoto, Shuhei Yamada, Noriko Miyake, Shujiro Hayashi, Atsushi Hatamochi, Jun Nakayama, Tomomi Yamaguchi, Ayana Hashimoto, Yoshihiro Nomura, Kazushige Takehana, Tomoki Kosho, and Takafumi Watanabe
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - General Subjects
  
  Volume: 1863 Issue: 3 Pages: 623-631
- DOI
  10.1016/j.bbagen.2018.12.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08251
[Journal Article] Hereditary Skeletal and Skin Disorders Caused by Defects in the Biosynthesis of Chondroitin/Dermatan Sulfate, and Molecular Mechanisms of Pulmonary Metastasis2019
- Author(s)
  水本秀二
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 139 Issue: 12 Pages: 1495-1500
- DOI
  10.1248/yakushi.19-00140
- NAID
  130007754062
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2019-12-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07054
[Journal Article] Roles of two types of heparan sulfate clusters in Wnt distribution and signaling in Xenopus2018
- Author(s)
  Yusuke Mii, Takayoshi Yamamoto, Ritsuko Takada, Shuji Mizumoto, Makoto Matsuyama, Shuhei Yamada, Shinji Takada, and Masanori Taira
- Journal Title
  
  Nature Communications
  
  Volume: 8 Issue: 1 Pages: 1973-1973
- DOI
  10.1038/s41467-017-02076-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08251, KAKENHI-PROJECT-17K19418, KAKENHI-PLANNED-24111002, KAKENHI-PROJECT-15K07951, KAKENHI-PUBLICLY-17H05782, KAKENHI-PROJECT-25251026, KAKENHI-PROJECT-15K14532
[Journal Article] Defect in dermatan sulfate in urine of patients with Ehlers-Danlos syndrome caused by a CHST14/D4ST1 deficiency2018
- Author(s)
  Shuji Mizumoto, Tomoki Kosho, Atsushi Hatamochi, Tomoko Honda, Tomomi Yamaguchi, Nobuhiko Okamoto, Noriko Miyake, Shuhei Yamada, and Kazuyuki Sugahara
- Journal Title
  
  Clinical Biochemistry
  
  Volume: 50 Issue: 12 Pages: 670-677
- DOI
  10.1016/j.clinbiochem.2017.02.018
- NAID
  120006398760
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08251, KAKENHI-PROJECT-15K07951
[Journal Article] Vascular abnormalities in the placenta of Chst14-/- fetuses: implications in the pathophysiology of perinatal lethality of the murine model and vascular lesions in human CHST14/D4ST1 deficiency2018
- Author(s)
  Takahiro Yoshizawa, Shuji Mizumoto, Yuki Takahashi, Shin Shimada, Kazuyuki Sugahara, Jun Nakayama, Shin’ichi Takeda, Yoshihiro Nomura, Yuko Nitahara-Kasahara, Takashi Okada, Kiyoshi Matsumoto, Shuhei Yamada, and Tomoki Kosho
- Journal Title
  
  Glycobiology
  
  Volume: 28 Issue: 2 Pages: 80-89
- DOI
  10.1093/glycob/cwx099
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08251, KAKENHI-PROJECT-16K19396, KAKENHI-PROJECT-15K07951
[Journal Article] Defects in Biosynthesis of Glycosaminoglycans Cause Hereditary Bone, Skin, Heart, Immune, and Neurological Disorders2018
- Author(s)
  Shuji Mizumoto
- Journal Title
  
  Trends in Glycoscience and Glycotechnology
  
  Volume: 30 Issue: 174 Pages: E67-E89
- DOI
  10.4052/tigg.1812.2E
- NAID
  130006744135
- ISSN
  0915-7352, 1883-2113
- Year and Date
  2018-05-25
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08251
[Journal Article] Screening of known disease genes in congenital scoliosis.2018
- Author(s)
  Takeda K, Kou I, Mizumoto S, Yamada S, Kawakami N, Nakajima M, Otomo N, Ogura Y, Miyake N, Matsumoto N, Kotani T, Sudo H, Yonezawa I, Uno K, Taneichi H, Watanabe K, Shigematsu H, Sugawara R, Taniguchi Y, Minami S, Nakamura M, Matsumoto M; Japan Early Onset Scoliosis Research Group, Watanabe K, Ikegawa S.
- Journal Title
  
  Molecular Genetics & Genomic Medicine
  
  Volume: - Issue: 6 Pages: 966-974
- DOI
  10.1002/mgg3.466
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10986, KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-16K08251
[Journal Article] Identification of novel LFNG mutations in spondylocostal dysostosis.2018
- Author(s)
  Otomo N, Mizumoto S, Lu HF, Takeda K, Campos-Xavier B, Mittaz-Crettol L, Guo L, Takikawa K, Nakamura M, Yamada S, Matsumoto M, Watanabe K, Ikegawa S.
- Journal Title
  
  Journal of human genetics
  
  Volume: - Issue: 3 Pages: 261-264
- DOI
  10.1038/s10038-018-0548-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10986, KAKENHI-PROJECT-16K08251, KAKENHI-PROJECT-17K16709
[Journal Article] The reduction of heparan sulphate in the glomerular basement membrane does not augment urinary albumin excretion2018
- Author(s)
  Satoshi Aoki, Akiko Saito-Hakoda, Takeo Yoshikawa, Kyoko Shimizu, Kiyomi Kisu, Susumu Suzuki, Kiyoshi Takagi, Shuji Mizumoto, Shuhei Yamada, Toin H. van Kuppevelt, Atsushi Yokoyama, Taiji Matsusaka, Hiroshi Sato, Sadayoshi Ito, and Akira Sugawara
- Journal Title
  
  Nephrology Dialysis Transplantation
  
  Volume: 33 Issue: 1 Pages: 26-33
- DOI
  10.1093/ndt/gfx218
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08251, KAKENHI-PROJECT-16K08606, KAKENHI-PROJECT-16K08645, KAKENHI-PROJECT-15K07951, KAKENHI-PROJECT-15K09420, KAKENHI-PROJECT-16K15492, KAKENHI-PROJECT-16H03252
[Journal Article] Impaired proteoglycan glycosylation, elevated TGF-β signaling, and abnormal osteoblast differentiation as the basis for bone fragility in a mouse model for gerodermia osteodysplastica2018
- Author(s)
  Wing Lee Chan, Magdalena Steiner, Tomasz Witkos, Johannes Egerer, Bjorn Busse, Shuji Mizumoto, 他17名
- Journal Title
  
  PLoS Genetics
  
  Volume: 14 Issue: 3 Pages: e1007242-e1007242
- DOI
  10.1371/journal.pgen.1007242
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08251
[Journal Article] Chondroitin sulfate N-acetylgalactosaminyltransferase-1 (CSGalNAcT-1) deficiency results in a mild skeletal dysplasia and joint laxity.2017
- Author(s)
  Julia Vodopiutz, Shuji Mizumoto, Ekkehard Lausch, Antonio Rossi, Sheila Unger, Nikolaus Janocha, Rainer Seidl, Susanne Greber-Platzer, Shuhei Yamada, Thomas Muller, Bernd Jilma, Rudolf Ganger, Andrea Superti-Furga, Shiro Ikegawa, Kazuyuki Sugahara, Andreas R. Janecke.
- Journal Title
  
  Human Mutation
  
  Volume: 38 Issue: 1 Pages: 34-38
- DOI
  10.1002/humu.23070
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07951, KAKENHI-PROJECT-16K08251
[Journal Article] Proteoglycan linkeropathies caused by defect in glycosaminoglycan-protein linker region2017
- Author(s)
  水本秀二
- Journal Title
  
  生化学
  
  Volume: 89 Issue: 2 Pages: 259-263
- DOI
  10.14952/SEIKAGAKU.2017.890259
- NAID
  40021203361
- ISSN
  0037-1017
- Year and Date
  2017-04-25
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08251
[Journal Article] Identification of biallelic EXTL3 mutations in a novel type of spondylo-epi-metaphyseal dysplasia2017
- Author(s)
  *Long Guo, *Nursel H Elcioglu, *Shuji Mizumoto, Zheng Wang, Bilge Noyan, Hatice M Albayrak, Shuhei Yamada, Naomichi Matsumoto, Noriko Miyake, Gen Nishimura, Shiro Ikegawa (equal contribution)
- Journal Title
  
  Journal of Human Genetics
  
  Volume: － Issue: 8 Pages: 797-801
- DOI
  10.1038/jhg.2017.38
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08251, KAKENHI-PROJECT-17K16710, KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-16H05357, KAKENHI-PROJECT-15K07951
[Journal Article] Pathophysiological Significance of Dermatan Sulfate Proteoglycans Revealed by Human Genetic Disorders2017
- Author(s)
  Shuji Mizumoto, Tomoki Kosho, Shuhei Yamada, Kazuyuki Sugahara
- Journal Title
  
  Pharmaceuticals
  
  Volume: 10 Issue: 2 Pages: 34-34
- DOI
  10.3390/ph10020034
- NAID
  120006335578
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K08251
[Journal Article] Structural analysis of chondroitin and dermatan sulfate in Receptor for Advanced Glycation End-products (RAGE) knockout mice2016
- Author(s)
  Shuji Mizumoto, Shuhei Yamada, Kazuyuki Sugahara
- Journal Title
  
  Bulletin of Research Institute of Meijo University
  
  Volume: 21 Pages: 209-212
- NAID
  40020904531
- Data Source
  KAKENHI-PROJECT-16K08251
[Journal Article] Functional validation of novel compound heterozygous variants in B3GAT3 resulting in severe osteopenia and fractures: expanding the disease phenotype.2016
- Author(s)
  *Florian Job, *Shuji Mizumoto, Laurie Smith, Natario Couser, Ashley Brazil, Howard Saal, Melanie Patterson, Margaret I. Gibson, Sarah Soden, Neil Miller, Isabelle Thiffault, Carol Saunders, Shuhei Yamada, Katrin Hoffmann, Kazuyuki Sugahara, Emily Farrow. (*equal contribution)
- Journal Title
  
  BMC Medical Genetics
  
  Volume: 17 Issue: 1 Pages: 86-86
- DOI
  10.1186/s12881-016-0344-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07951, KAKENHI-PROJECT-16K08251
[Journal Article] Molecular interactions between chondroitin-dermatan sulfate and growth factors/receptors/matrix proteins2016
- Author(s)
  Shuji Mizumoto, Shuhei Yamada, Kazuyuki Sugahara
- Journal Title
  
  Curr. Opin. Struct. Biol.
  
  Volume: 34 Pages: 35-42
- DOI
  10.1016/j.sbi.2015.06.004
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K07951, KAKENHI-PUBLICLY-26110719, KAKENHI-PROJECT-25860037
[Journal Article] Pivotal Role of Carbohydrate Sulfotransferase 15 in Fibrosis and Mucosal Healing in Mouse Colitis2016
- Author(s)
  Suzuki K, Arumugam S, Yokoyama J, Kawauchi Y, Honda Y, Sato H, Aoyagi Y, Terai S, Okazaki K, Suzuki Y, Mizumoto S, Sugahara K, Atreya R, Neurath MF, Watanabe K, Hashiguchi T, Yoneyama H, Asakura H: .
- Journal Title
  
  PloS one
  
  Volume: 11 Issue: 7 Pages: 1-17
- DOI
  10.1371/journal.pone.0158967
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293175, KAKENHI-PROJECT-15K08966, KAKENHI-PROJECT-16K08251
[Journal Article] Mutations in biosynthetic enzymes for the protein linker region of chondroitin/dermatan/heparan sulfate cause skeletal and skin dysplasias2015
- Author(s)
  Shuji Mizumoto, Shuhei Yamada, Kazuyuki Sugahara
- Journal Title
  
  BioMed Res. Int.
  
  Volume: 2015 Pages: 861752-861752
- DOI
  10.1155/2015/861752
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K07951, KAKENHI-PUBLICLY-26110719, KAKENHI-PROJECT-25860037
[Journal Article] Skeletal dysplasia in a consanguineous clan from the island of Nias/Indonesia is caused by a novel mutation in B3GAT3.2015
- Author(s)
  Birgit S. Budde, Shuji Mizumoto, Ryo Kogawa, Christian Becker, Janine Altmuller, Holger Thiele, Franz Ruschendorf, Mohammad R. Toliat, Gerrit Kaleschke, Johannes M. Hammerle, Wolffang Hohne, Kazuyuki Sugahara, Peter Nurnberg, Ingo Kennerknecht.
- Journal Title
  
  Human Genetics
  
  Volume: in press Issue: 7 Pages: 691-704
- DOI
  10.1007/s00439-015-1549-2
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670018, KAKENHI-PUBLICLY-26110719, KAKENHI-PROJECT-25860037
[Journal Article] Receptor protein tyrosine phosphatase beta/zeta is a functional binding partner for vascular endothelial growth factor.2015
- Author(s)
  Marina Koutsioumpa, Evangelia Poimenidi, Evangelia Pantazaka, Christina Theodoropoulou, Angeliki Skoura, Vasileios Megalooikonomou, Nelly Kieffer, Jose Courty, Shuji Mizumoto, Kazuyuki Sugahara, and Evangelia Papadimitriou.
- Journal Title
  
  Molecular Cancer
  
  Volume: 14 Issue: 1 Pages: 19-19
- DOI
  10.1186/s12943-015-0287-3
- NAID
  120005906915
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670018, KAKENHI-PUBLICLY-26110719, KAKENHI-PROJECT-25860037
[Journal Article] Human genetic disorders and knockout mice deficient in glycosaminoglycan2014
- Author(s)
  Shuji Mizumoto, Shuhei Yamada, and Kazuyuki Sugahara
- Journal Title
  
  BioMed Research International
  
  Volume: 2014 Pages: 495764-495764
- DOI
  10.1155/2014/495764
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590071, KAKENHI-PROJECT-25860037, KAKENHI-PUBLICLY-26110719
[Journal Article] Sulfation patterns of exogenous chondroitin sulfate affect chondrogenic differentiation of ATDC5 cells2014
- Author(s)
  Daisuke Kawamura, Tadanao Funakoshi, Shuji Mizumoto, Kazuyuki Sugahara, and Norimasa Iwasaki
- Journal Title
  
  Journal of Orthopaedic Science
  
  Volume: 19 Issue: 6 Pages: 1028-1035
- DOI
  10.1007/s00776-014-0643-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25860037, KAKENHI-PUBLICLY-26110719
[Journal Article] Effects of sesamin on the biosynthesis of chondroitin sulfate proteoglycans in human articular chondrocytes in primary culture2014
- Author(s)
  Peraphan Pothacharoen, Sumet Najarus, Jongkolnee Settakorn, Shuji Mizumoto, Kazuyuki Sugahara, and Prachya Kongtawelert
- Journal Title
  
  Glycoconjugate Journal
  
  Volume: 31 Issue: 3 Pages: 221-230
- DOI
  10.1007/s10719-013-9514-6
- NAID
  120005600748
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860037
[Journal Article] Human genetic disorders caused by defective genes encoding biosynthetic enzymes for sulfated glycosaminoglycans2013
- Author(s)
  Shuji Mizumoto, Shiro Ikegawa, andKazuyuki Sugahara
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 288 Issue: 16 Pages: 10953-10961
- DOI
  10.1074/jbc.r112.437038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790066, KAKENHI-PROJECT-25860037
[Journal Article] Expression of N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase involved in chondroitin sulfate synthesis is responsible for pulmonary metastasis2013
- Author(s)
  Shuji Mizumoto, Moto Watanabe, Shuhei Yamada, Kazuyuki Sugahara
- Journal Title
  
  BioMed Research International
  
  Volume: 2013 Pages: 656319-656319
- NAID
  120005906914
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] Loss of dermatan sulfate epimerase (DSE) function results in musculocontractural Ehlers-Danlos syndrome2013
- Author(s)
  Thomas Muller, Shuji Mizumoto, Indrajit Suresh, Yoshie Komatsu, Julia Vodopiutz, Munis Dundar, Volker Straub, Arno Lingenhel, Andreas Melmer, Silvia Lechner, Johannes Zschocke, Kazuyuki Sugahara, Andreas R Janecke
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 22 Issue: 18 Pages: 3761-3772
- DOI
  10.1093/hmg/ddt227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790066, KAKENHI-PROJECT-25860037
[Journal Article] Glycosaminoglycans are functional ligands for Receptor for Advanced Glycation End-products (RAGE) in tumors2013
- Author(s)
  Mizumoto, S., and Sugahara, K.
- Journal Title
  
  FEBS Journal
  
  Volume: 280 Issue: 10 Pages: 2462-2470
- DOI
  10.1111/febs.12156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016, KAKENHI-PROJECT-23790066, KAKENHI-PROJECT-25670018, KAKENHI-PROJECT-25860037
[Journal Article] Glycosaminoglycans are functional ligands for Receptor for Advanced Glycation End-products (RAGE) in tumors2013
- Author(s)
  Shuji Mizumoto, Kazuyuki Sugahara
- Journal Title
  
  FEBS Journal
  
  Volume: 280(10) Pages: 2462-2470
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] Interaction of chondroitin sulfate and dermatan sulfate from various biological sources with heparin-binding growth factors and cytokines2013
- Author(s)
  Shuji Mizumoto, Duriya Fongmoon, Kazuyuki Sugahara
- Journal Title
  
  Glycoconjugate Journal
  
  Volume: in press Issue: 6 Pages: 619-632
- DOI
  10.1007/s10719-012-9463-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790066, KAKENHI-PUBLICLY-24110501, KAKENHI-PROJECT-25860037
[Journal Article] Clinical and radiographic features of the autosomal recessive form of brachyolmia caused by PAPSS2 mutations2013
- Author(s)
  Aritoshi Iida*, Pelin Ozlem Simsek-Kiper*, Shuji Mizumoto*, Touma Hoshino, Nursel Elcioglu, Eva Horemuzova, Stefan Geiberger, Gozde Yesil, Hulya Kayserili, Gulen Eda Unite, Koray Boduroglu, Shigehiko Watanabe, Hirofumi Ohashi, Yasemin Alanay, Kazuyuki Sugahara, Gen Nishimura, Shiro Ikegawa (*equal contribution)
- Journal Title
  
  Human Mutation
  
  Volume: 34 Issue: 10 Pages: 1381-1386
- DOI
  10.1002/humu.22377
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860037
[Journal Article] Novel highly sulfated hexasaccharide sequences isolated from chondroitin sulfate of shark fin cartilage: Insights into the sugar sequences with bioactivities2013
- Author(s)
  Shuji Mizumoto, Saori Murakoshi, Kittiwan Kalayanamitra, Sarama Sathyaseelan Deepa, Shigeyuki Fukui, Prachya Kongtawelert, Shuhei Yamada, and Kazuyuki Sugahara
- Journal Title
  
  Glycobiology
  
  Volume: 23 Issue: 2 Pages: 155-168
- DOI
  10.1093/glycob/cws137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790066, KAKENHI-PUBLICLY-24110501
[Journal Article] Reduction of Chondroitin 4-<i>O</i>-Sulfotransferase-1 Expression Causes Costello Syndrome2013
- Author(s)
  Shuji Mizumoto
- Journal Title
  
  Trends in Glycoscience and Glycotechnology
  
  Volume: 25 Issue: 142 Pages: 87-89
- DOI
  10.4052/tigg.25.87
- NAID
  10031190623
- ISSN
  0915-7352, 1883-2113
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790066, KAKENHI-PROJECT-25860037
[Journal Article] Mutations in B3GALT6 which Encodes a Glycosaminoglycan Linker Region Enzyme Cause a Spectrum of Skeletal and Connective Tissue Disorders2013
- Author(s)
  Masahiro Nakajima, Shuji Mizumoto et al.
- Journal Title
  
  American Journal of Human Genetics
  
  Volume: in press Issue: 6 Pages: 927-934
- DOI
  10.1016/j.ajhg.2013.04.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790066, KAKENHI-PROJECT-24592230, KAKENHI-PROJECT-25293235, KAKENHI-PROJECT-25860037, KAKENHI-PROJECT-25860915
[Journal Article] Expression of N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase involved in chondroitin sulfate synthesis is responsible for pulmonary metastasis2013
- Author(s)
  Mizumoto, S., Watanabe, M., Yamada, S., and Sugahara, K.
- Journal Title
  
  BioMed Research International
  
  Volume: 2013 Pages: 656319-656319
- DOI
  10.1155/2013/656319
- NAID
  120005906914
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016, KAKENHI-PROJECT-23790066
[Journal Article] Bone ana skin disorders caused by a disturbance in the bioynthesis of chondroitin sulfate and dermatan sulfate2012
- Author(s)
  Mizumoto, S., Sugahara, K.
- Journal Title
  
  Extracellular matrix : Pathobiology and signaling
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] Receptor for Advanced Glycation End Products (RAGE) Functions as a Receptor for Specific Sulfated Glycosaminoglycans, and Anti-RAGE Antibody or The Sulfated Glycosaminoglycans Delivered in vivo Inhibit Pulmonary Metastasis of Tumor Cells2012
- Author(s)
  Shuji Mizumoto, Jun Takahashi, Kazuyuki Sugahara
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 287(23) Pages: 18985-18994
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] Hyaluronidases have strong hydrolytic activity toward chondroitin 4-sulfate comparable to that for hyaluronan2012
- Author(s)
  Tomoko Honda, Tomoyuki Kaneiwa, Shuji Mizumoto, Kazuyuki Sugahara, and Shuhei Yamada
- Journal Title
  
  Biomolecules
  
  Volume: 2 Issue: 4 Pages: 549-563
- DOI
  10.3390/biom2040549
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590071
[Journal Article] Chondroitin sulfate E-type structure at tumor cell surface is involved in experimental metastasis2012
- Author(s)
  Kazuyuki SUGAHRA, Shuji MIZUMOTO
- Journal Title
  
  Advances in Experimental Medicine and Biology
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] Glycosaminoglycan chain analysis and characterization (Glycosylation/Epimerization)2012
- Author(s)
  Shuji Mizumoto and Kazuyuki Sugahara
- Journal Title
  
  Methods in Molecular Biology, (Proteoglycans: Methods and Protocols)
  
  Volume: 836 Pages: 99-115
- DOI
  10.1007/978-1-61779-498-8_7
- ISBN
  9781617794971, 9781617794988
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790066
[Journal Article] Receptor for Advanced Glycation End Products (RAGE) Functions as a Receptor for Specific Sulfated Glycosaminoglycans, and Anti-RAGE Antibody or The Sulfated Glycosaminoglycans Delivered in vivo Inhibit Pulmonary Metastasis of Tumor Cells2012
- Author(s)
  Shuji MIZUMOTO, Jun TAKAHASHI, Kazuyuki SUGAHARA
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] Identification of amino acid residues required for the substrate specificity of human and mouse chondroitin sulfate hydrolase (conventional hyaluronidase-4)2012
- Author(s)
  Tomoyuki Kaneiwa, Anzu Miyazaki, Ryo Kogawa, Shuji Mizumoto, Kazuyuki Sugahara, and Shuhei Yamada
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 287 Issue: 50 Pages: 42119-42128
- DOI
  10.1074/jbc.m112.360693
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590071
[Journal Article] Receptor for Advanced Glycation End Products (RAGE) Functions as a Receptor for Specific Sulfated Glycosaminoglycans, and Anti-RAGE Antibody or The Sulfated Glycosaminoglycans Delivered in vivo Inhibit Pulmonary Metastasis of Tumor Cells2012
- Author(s)
  Mizumoto, S., Takahashi, J., and Sugahara, K.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 287 Issue: 23 Pages: 18985-18994
- DOI
  10.1074/jbc.m111.313437
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016, KAKENHI-PROJECT-23790066
[Journal Article] ISCSM2011 Chondroitin sulfate E-type structure at tumor cell surface is involved in experimental metastasis2012
- Author(s)
  Sugahara, K., and Mizumoto, S.
- Journal Title
  
  Advances in Experimental Medicine and Biology
  
  Volume: 749 Pages: 33-45
- DOI
  10.1007/978-1-4614-3381-1_3
- ISBN
  9781461433804, 9781461433811
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016, KAKENHI-PROJECT-23790066
[Journal Article] Faulty initiation of proteoglycan synthesis causes cardiac and joint defects2011
- Author(s)
  Baasanjav, S., Al-Gazali, L., Hashiguchi, T., Mizumoto, S., Fischer, B., Horn, D., Seelow, D., Ali, B.R., Aziz, S.A.A., Langer, R., Saleh,A.A.H., Becker, C., Nunberg,G., Cantagrel, V., Gleeson, J.G., Gomez, D., Michel, J-.B., Stricker, S., Lindner, T.H., Nunberg, P., Sugahara, K., Mundlos, S., Hoffmann, K.
- Journal Title
  
  American Journal of Human Genetics
  
  Volume: 89 Issue: 1 Pages: 15-27
- DOI
  10.1016/j.ajhg.2011.05.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016, KAKENHI-PROJECT-23790066
[Journal Article] Involvement of HNK-1 Sulfotransferase in the Biosynthesis of Chondroitin Sulfate and the GlcUA(3-O-sulfate)-Gal-Gal-Xyl Tetrasaccharide Found in α-Thrombomodulin from Human Urine2011
- Author(s)
  Taishi Hashiguchi, Shuji Mizumoto, Yuko Nishimura, Jun-ichi Tamura, Shuhei Yamada, Kazuyuki Sugahara
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 286(38) Pages: 33003-33011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] Dermatan sulfate epimerase 2 is the predominant isozyme in the formation of the chondroitin sulfate/dermatan sulfate hybrid structure in postnatal developing mouse brain.2011
- Author(s)
  Akatsu C., Mizumoto S., Kaneiwa T., Maccarana M., Malmstrom A., Yamada S., Sugahara K.
- Journal Title
  
  Glycobiology 21(5)
  
  Pages: 565-574
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Involvement of HNK-1 sulfotransferase in the biosynthesis of chondro itin sulfate and the GlcA(3-O-sulfate)-Gal-Gal-Xyl tetrasaccharide found in α-thrombomodulin from human urine2011
- Author(s)
  Taishi Hashiguchi
- Journal Title
  
  J.Biol.Chem
  
  Volume: 286 Issue: 38 Pages: 33003-33011
- DOI
  10.1074/jbc.m111.279174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590057, KAKENHI-PROJECT-23390016, KAKENHI-PROJECT-23790066
[Journal Article] Demonstration of the hepatocyte growth factor signaling pathway in the in vitro neuritogenic activity of chondroitin sulfate from ray fish cartilage2011
- Author(s)
  Taishi Hashiguchi
- Journal Title
  
  Bionchim.Biophys.Acta
  
  Volume: 1810 Issue: 4 Pages: 406-413
- DOI
  10.1016/j.bbagen.2011.01.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590057, KAKENHI-PROJECT-23390016
[Journal Article] Demonstration of the Hepatocyte Growth Factor Signaling Pathway in the in vitro Neuritogenic Activity of Chondroitin Sulfate from Ray Fish Cartilage.2011
- Author(s)
  Hashiguchi Y., Kobayashi T., Fongmoon D., Shetty A.K., Mizumoto S., Miyamoto N., Nakamura T., Yamada S., Sugahara K.
- Journal Title
  
  Biochim.Biophys.Acta 1810(4)
  
  Pages: 406-413
- NAID
  120002934270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Faulty initiation of proteoglycan synthesis causes cardiac and joint defects.2011
- Author(s)
  Baasanjav S., Al-Gazali L., Hashiguchi T., Mizumoto S., Fischer B., Horn D., Seelow D., Ali B.R., Aziz S.A.A., Langer R., Saleh A.A.H., Becker C., Nurnberg G., Cantagrel V., Gleeson J.G., Gomez D., Michel J.-B., Stricker S., Lindner T.H., Nurnberg P., Sugahara K., Mundlos S., Hoffmann K.
- Journal Title
  
  Am.J.Hum.Genet. (in press.)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Disorder of Biosynthesis of Dermatan Sulfate Causes a New Type of Ehlers-Danlos Syndrome2011
- Author(s)
  Kazuyuki Sugahara and Shuji Mizumoto
- Journal Title
  
  Trends in Glycoscience and Glycotechnology
  
  Volume: 23 Issue: 132 Pages: 197-199
- DOI
  10.4052/tigg.23.197
- NAID
  10030388941
- ISSN
  0915-7352, 1883-2113
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790066
[Journal Article] Demonstration of the hepatocyte growth factor signaling pathway in the in vitro neuritogenic activity of chondroitin sulfate from ray fish cartilage2011
- Author(s)
  Taishi Hashiguchi, Takanari Kobayashi, Duriya Fongmoon, Ajaya Kumar Shetty, Shuji Mizumoto, Nobuyuki Miyamoto, Toshikazu Nakamura, Shuhei Yamada, Kazuyuki Sugahara
- Journal Title
  
  Biochimica et Biophysica Acta (General Subjects)
  
  Volume: 1810(4) Pages: 406-413
- NAID
  120002934270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] Faulty initiation of proteoglycan synthesis causes cardiac and joint defects2011
- Author(s)
  Sevjidmaa Baasanjav, Lihadh Al-Gazali, Taishi Hashiguchi, Shuji Mizumoto, Bjoern Fischer, Denise Horn, Dominik Seelow, Bassam R. Ali, Samir A.A. Aziz, Ruth Langer, Ahmed A.H. Saleh, Christian Becker, Gudrun Nürnberg, Vincent Cantagrel, Joseph G. Gleeson, Delphine Gomez, Jean-Baptiste Michel, Sigmar Stricker, Tom H. Lindner, Peter Nürnberg, Kazuyuki Sugahara, Stefan Mundlos, Katrin Hoffmann
- Journal Title
  
  American Journal of Human Genetics
  
  Volume: 89(1) Pages: 15-27
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] Dermatan sulfate epimerase 2 is the predominant isozyme in the formation of the chondroitin sulfate/dermatan sulfate hybrid structure in postnatal developing mouse brain2011
- Author(s)
  Chizuru Akatsu, Shuji Mizumoto, Tomoyuki Kaneiwa, Marco Maccarana, Anders Malmström, Shuhei Yamada, Kazuyuki Sugahara
- Journal Title
  
  Glycobiology
  
  Volume: 21(5) Pages: 565-574
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] Dermatan sulfate epimerase 2 is the predominant isozyme in the formation of the chondroitin sulfate/dermatan sulfate hybrid structure in postnatal developing mouse brain2011
- Author(s)
  Akatsu, C., Mizumoto, S., Kaneiwa, T., Maccarana, M., Malmstrom,. A., Yamada, S., Sugahara, K.
- Journal Title
  
  Glycobiology
  
  Volume: 21 Issue: 5 Pages: 565-574
- DOI
  10.1093/glycob/cwq208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] Analysis of the structure and neuritogenic activity of chondroitin sulfate/dermatan sulfate hybrid chains from porcine fetal membranes.2010
- Author(s)
  Hashiguchi T., Mizumoto S., Yamada S., Sugahara K.
- Journal Title
  
  Glycoconjugate J. 27(1)
  
  Pages: 49-60
- NAID
  120004043734
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Synthesis of the glycosaminoglycan-protein linkage tetraosyl peptide moieties of betaglycan, which serve as a hexosamine acceptor for enzymatic glycosyl transfer.2010
- Author(s)
  Tamura J., Nakamura-Yamamoto T., Nishimura Y., Mizumoto S., Takahashi J., Sugahara K.
- Journal Title
  
  Carbohydr.Res. 345(15)
  
  Pages: 2115-2123
- NAID
  120002548780
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Loss-of-function mutations of CHST14 in a new type of Ehlers-Danlos syndrome.2010
- Author(s)
  Miyake N., Kosho T., Mizumoto S., Furuichi T., Hatamochi A., Nagashima Y., Arai E., Takahashi K., Kawamura R., Wakui K., Takahashi J., Kato H., Yasui H., Ishida T., Ohashi H., Nishimura G., Shiina M., Saitsu H., Tsurusaki Y., Doi H., Fukushima Y., Ikegawa S., Yamada S., Sugahara K., Matsumoto N.
- Journal Title
  
  Hum.Mutat.(Equal contribution) 31(8)
  
  Pages: 966-974
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Chondroitin 4-O-sulfotransferase-1 is required for somitic muscle development and motor axon guidance in zebrafish.2009
- Author(s)
  Shuji Mizumoto
- Journal Title
  
  Biochem. J. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Chondroitin Hydrolase in Caenorhabditis elegans.2009
- Author(s)
  Yamada S., Mizumoto S., Sugahara K.
- Journal Title
  
  Trends Glycosci.Glycotechnol. 21(119)
  
  Pages: 149-162
- NAID
  10026976542
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Chondroitin 4-O-sulfotransferase-1 is required for somitic muscle development and motor axon guidance in zebrafish2009
- Author(s)
  Mizumoto S., Mikami T., Yasunaga D., Kobayashi N., Yamauchi H., Miyake A., Itoh N., Kitagawa H., Sugahara K.
- Journal Title
  
  Biochem.J.(Equal contribution) 419(2)
  
  Pages: 387-399
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Important role of heparan sulfate in postnatal islet growth and insulin secretion.2009
- Author(s)
  Takahashi I., Noguchi N., Nata K., Yamada S., Kaneiwa T., Mizumoto S., Ikeda T., Sugihara K., Asano M., Yoshikawa T., Yamauchi A., Shervani N. J., Uruno A., Kato I., Unno M., Sugahara K., Takasawa S., Okamoto H., Sugawara A.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 383(1)
  
  Pages: 113-118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] グリコサミノグリカン-生体シグナル分子相互作用2009
- Author(s)
  水本秀二
- Journal Title
  
  遺伝子医学MOOK (別冊)
  
  Pages: 223-230
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Chondroitin 4-O-sulfotransferase-1 is required for somitic muscle development and motor axon guidance in zebrafish.2009
- Author(s)
  Shuji Mizumoto
- Journal Title
  
  Biochem. J. 419
  
  Pages: 387-399
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Isolation and characterization of a novel chondroitin sulfate from squid liver integument rich in N-acetylgalactosamine(4,6-O-disulfate) and glucuronate(3-O-sulfate) residues.2009
- Author(s)
  Shetty A.K., Kobayashi T., Mizumoto S., Narumi M., Kudo Y., Yamada S., Sugahara K.
- Journal Title
  
  Carbohydr.Res.(Equal contribution) 344(12)
  
  Pages: 1526-1532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] グリコサミノグリカン合成の微調節メカニズム2008
- Author(s)
  水本秀二
- Journal Title
  
  蛋白質核酸酵素 53
  
  Pages: 1448-1455
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Patent] グリコサミノグリカン分解促進剤2009
- Inventor(s)
  菅原一幸, 山田修平, 水本秀二, 金岩知之
- Industrial Property Rights Holder
  北海道大学
- Industrial Property Number
  2009-238490
- Filing Date
  2009-10-15
- Data Source
  KAKENHI-PROJECT-20390019
[Patent] グリコサミノグリカン分解促進剤2009
- Inventor(s)
  菅原一幸、山田修平、水本秀二、金岩知之
- Industrial Property Rights Holder
  北海道大学
- Industrial Property Number
  2009-238490
- Filing Date
  2009-10-15
- Data Source
  KAKENHI-PROJECT-20390019
[Presentation] グリコサミノグリカン生合成に関わるキシロース転移酵素の遺伝性疾患を発症する変異型の酵素活性測定2024
- Author(s)
  野原若菜、清益慎也、山田修平、水本秀二
- Organizer
  日本薬学会第144回年会
- Data Source
  KAKENHI-PROJECT-21K06552
[Presentation] Hereditary bone disorders caused by reduced activity of xylosyltransferases involved in glycosaminoglycan biosynthesis2023
- Author(s)
  Shuhei Yamada, Asaka Takayasu, Shinya Kiyomasu, Shuji Mizumoto
- Organizer
  The 26th International Glycoconjugate Symposium (Glyco26)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06552
[Presentation] 筋拘縮型エーラス・ダンロス症候群（mcEDS）の疾患モデルマウスを用いた包括的骨病態解析2023
- Author(s)
  高橋有希、吉沢隆浩、水本秀二、小野史子、嶋田新、上原将志、渡邉敬文、山田修平、高橋淳、古庄知己
- Organizer
  第70回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-23K07780
[Presentation] 脳のグルタミン酸作動性神経特異的にヘパラン硫酸生合成酵素Extl3を欠損させたマウスにおける脳機能解析2023
- Author(s)
  沼崎礼奈、三河範花、髙羽里佳、衣斐大祐、水本秀二、平松正行、菅原明、山田修平
- Organizer
  糖鎖科学中部拠点　第18回若手の力フォーラム
- Data Source
  KAKENHI-PROJECT-21K06552
[Presentation] ウリジン二リン酸(UDP)によるUDP-グルクロン酸デカルボキシラーゼ、キシロース転移酵素およびグルクロン酸転移酵素活性への影響2023
- Author(s)
  水本秀二、髙安麻香、古川憲司、山田修平
- Organizer
  糖鎖科学中部拠点　第19回若手の力フォーラム
- Data Source
  KAKENHI-PROJECT-23K06142
[Presentation] Effect of uridine diphosphate on the enzymatic activities of UDP-GlcA decarboxylase, xylosyltransferase, and glucuronyltransferase2023
- Author(s)
  Shuji Mizumoto, Asaka Takayasu, Kenji Furukawa, and Shuhei Yamada
- Organizer
  2023 Annual Meeting of Society for Glycobiology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06142
[Presentation] Analysis of T cell differentiation in mice lacking heparan sulfate biosynthetic enzyme Extl32023
- Author(s)
  Chiaki Asaoka, Natsu Yamazaki, Shuji Mizumoto, Tadashi Yamashita, Akira Sugawara, Shuhei Yamada
- Organizer
  The 26th International Glycoconjugate Symposium (Glyco26)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06142
[Presentation] デビュクオア骨異形成症や脊椎・眼症候群を引き起こすキシロース転移酵素のアミノ酸置換による酵素活性への影響2023
- Author(s)
  水本秀二、清益慎也、山田修平
- Organizer
  日本薬学会第143回年会
- Data Source
  KAKENHI-PROJECT-21K06552
[Presentation] グルタミン酸作動性神経特異的にヘパラン硫酸(HS)合成酵素EXTL3を欠損させたマウス脳におけるHS、Extl3の発現解析2023
- Author(s)
  沼崎礼奈、髙羽里佳、衣斐大祐、水本秀二、平松正行、菅原明、山田修平
- Organizer
  第69回日本薬学会東海支部総会・大会
- Data Source
  KAKENHI-PROJECT-21K06552
[Presentation] 遺伝性骨疾患を引き起こすキシロース転移酵素の変異による酵素活性への影響2023
- Author(s)
  水本秀二、清益慎也、山田修平
- Organizer
  糖鎖科学中部拠点　第18回若手の力フォーラム
- Data Source
  KAKENHI-PROJECT-21K06552
[Presentation] Chst14 KOマウスを用いた筋拘縮型エーラス・ダンロス症候群の病態解明2023
- Author(s)
  吉沢隆浩、高橋有希、嶋田新、小野史子、岳鳳鳴、水本秀二、山中仁木、山田修平、古庄知己
- Organizer
  信州実験動物研究会第40回研究発表会
- Data Source
  KAKENHI-PROJECT-19K08745
[Presentation] Effect of uridine diphosphate on the enzymatic activities of glycosaminoglycan biosynthetic enzymes, xylosyl- and glucuronyl-transferases2023
- Author(s)
  Asaka Takayasu, Shuhei Yamada, Shuji Mizumoto
- Organizer
  The 26th International Glycoconjugate Symposium (Glyco26)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06552
[Presentation] Analyses of hereditary disorders caused by defects in biosynthesis of chondroitin/dermatan/heparan sulfate2023
- Author(s)
  Shuji Mizumoto
- Organizer
  89th Harden Conference - Proteoglycans: Matrix Master Regulators 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06142
[Presentation] 筋拘縮型エーラス・ダンロス症候群モデルマウスにおける大腸の解析2023
- Author(s)
  小野史子、吉沢隆浩、高橋有希、水本秀二、古庄知己
- Organizer
  第70回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-23K07780
[Presentation] Effect of uridine diphosphate on the enzymatic activities of UDP-GlcA decarboxylase, xylosyltransferase, and glucuronyltransferase20232023
- Author(s)
  Shuji Mizumoto, Asaka Takayasu, Kenji Furukawa, Shuhei Yamada
- Organizer
  Annual Meeting of Society for Glycobiology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06552
[Presentation] ラット骨格筋細胞株L6のライセートを用いたマトリグリカン分解活性の検出2023
- Author(s)
  今井恵美、水本秀二、山田修平
- Organizer
  糖鎖科学中部拠点　第19回若手の力フォーラム
- Data Source
  KAKENHI-PROJECT-23K06142
[Presentation] Pathophysiological investigation on skeletal manifestations of Musculocontractural Ehlers Danlos Syndrome2023
- Author(s)
  Yuki Takahashi, Takahiro Yoshizawa, Fumiko Ono, Shuji Mizumoto, Shuhei Yamada, Tomoki Kosho
- Organizer
  Human Genetics Asia 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07780
[Presentation] グルタミン酸作動性神経特異的にヘパラン硫酸生合成酵素Extl3を完全欠損させたマウスの解析2023
- Author(s)
  荻堂百佳、髙羽里佳、衣斐大祐、水本秀二、平松正行、菅原　明、山田修平
- Organizer
  第55回日本結合組織学術大会
- Data Source
  KAKENHI-PROJECT-21K06552
[Presentation] Hereditary Bone Disorders Caused by Reduced Activity of Xylosyltransferases Involved in Glycosaminoglycan Biosynthesis2023
- Author(s)
  Shuhei Yamada, Asaka Takayasu, Shinya Kiyomasu, Shuji Mizumoto
- Organizer
  The 26th International Glycoconjugate Symposium (Glyco26)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06142
[Presentation] 糸球体たこ足細胞特異的にヘパラン硫酸生合成酵素EXTL3を欠損させたマウスにおけるヘパラン硫酸の解析2023
- Author(s)
  石垣凜空馬、村松　尚、水本秀二、松阪泰二、菅原　明、山田修平
- Organizer
  第69回日本薬学会東海支部総会・大会
- Data Source
  KAKENHI-PROJECT-21K06552
[Presentation] Effect of Uridine Diphosphate on the Enzymatic Activities of Glycosaminoglycan Biosynthetic Enzymes, Xylosyl- and Glucuronyl-transferases2023
- Author(s)
  Asaka Takayasu, Shuhei Yamada, Shuji Mizumoto
- Organizer
  The 26th International Glycoconjugate Symposium (Glyco26)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06142
[Presentation] T細胞特異的にヘパラン硫酸生合成酵素Extl3を欠損させたマウスにおけるT細胞分化の解析2023
- Author(s)
  浅岡千晶、山﨑奈都、水本秀二、山下匡、菅原明、山田修平
- Organizer
  糖鎖科学中部拠点　第18回若手の力フォーラム
- Data Source
  KAKENHI-PROJECT-21K06552
[Presentation] ウリジン二リン酸(UDP)によるUDP-グルクロン酸デカルボキシラーゼ、キシロース転移酵素およびグルクロン酸転移酵素活性への影響2023
- Author(s)
  水本秀二、髙安麻香、古川憲司、山田修平
- Organizer
  糖鎖科学中部拠点　第19回若手の力フォーラム
- Data Source
  KAKENHI-PROJECT-21K06552
[Presentation] Analysis of T cell differentiation in mice lacking heparan sulfate biosynthetic enzyme Extl32023
- Author(s)
  Chiaki Asaoka, Natsu Yamazaki, Shuji Mizumoto, Tadashi Yamashita, Akira Sugawara, Shuhei Yamada
- Organizer
  The 26th International Glycoconjugate Symposium (Glyco26)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06552
[Presentation] グリコサミノグリカン生合成に関わるキシロース転移酵素の遺伝性疾患を引き起こす変異が及ぼす酵素活性への影響2022
- Author(s)
  清益慎也、花立妃子、伊藤有美、山田修平、水本秀二
- Organizer
  日本薬学会第142回年会
- Data Source
  KAKENHI-PROJECT-21K06552
[Presentation] ヘパラン硫酸生合成酵素EXTL3をT細胞特異的に欠損させたマウスの解析2022
- Author(s)
  山﨑奈都、大橋礼、大橋里帆、水本秀二、山下匡、菅原明、山田修平
- Organizer
  日本薬学会第142回年会
- Data Source
  KAKENHI-PROJECT-21K06552
[Presentation] β3ガラクトース転移酵素6 (b3galt6) のゼブラフィッシュ変異体におけるコンドロイチン/デルマタン/ヘパラン硫酸の定量解析2022
- Author(s)
  水本秀二、Sarah Delbaere, Adelbert De Clercq, Fredrik Noborn, Jan Willem Bek, Lien Alluyn, Charlotte Gistelinck, Delfien Syx, Phil L. Salmon, Paul J. Coucke, Goran Larson, 山田修平, Andy Willaert, Fransiska Malfait
- Organizer
  日本薬学会第142回年会、名古屋、3/28
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] 筋拘縮型エーラス・ダンロス症候群(mcEDS)疾患モデルマウスを用いた骨病態解明への取り組み2022
- Author(s)
  高橋有希、吉沢隆浩、水本秀二、山田修平、古庄知己
- Organizer
  日本人類遺伝学会第67回大会
- Data Source
  KAKENHI-PROJECT-19K08745
[Presentation] 筋拘縮型エーラス・ダンロス症候群モデルマウスにおける大腸の解析2022
- Author(s)
  小野史子、吉沢隆浩、高橋有希、水本秀二、古庄知己
- Organizer
  第3回日本エーラス・ダンロス症候群(EDS)研究会
- Data Source
  KAKENHI-PROJECT-19K08745
[Presentation] グリコサミノグリカン生合成に関わるキシロース転移酵素の遺伝性疾患を引き起こす変異が及ぼす酵素活性への影響2022
- Author(s)
  清益慎也、花立妃子、伊藤有美、山田修平、水本秀二
- Organizer
  日本薬学会第142回年会、名古屋、3/28
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] プロテオグリカン糖側鎖の生合成不全に起因する遺伝性の骨・関節・皮膚疾患2022
- Author(s)
  水本秀二
- Organizer
  名城大学総合研究所難治性疾患発症メカニズム研究センター第3回セミナー
- Data Source
  KAKENHI-PROJECT-19H03616
[Presentation] グリコサミノグリカン生合成に関わるキシロース転移酵素1および2の遺伝性疾患を引き起こす変異が及ぼす酵素活性への影響2022
- Author(s)
  清益慎也、花立妃子、伊藤有美、山田修平、水本秀二
- Organizer
  糖鎖科学中部拠点　第17回若手の力フォーラム
- Data Source
  KAKENHI-PROJECT-21K06552
[Presentation] グリコサミノグリカン生合成に関わるキシロース転移酵素1および2の遺伝性疾患を引き起こす変異が及ぼす酵素活性への影響2022
- Author(s)
  清益慎也、花立妃子、伊藤有美、山田修平、水本秀二
- Organizer
  糖鎖科学中部拠点　第17回若手の力フォーラム、岐阜、1/13
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] T細胞特異的EXTL3欠損マウスにおけるT細胞分化の遅延2022
- Author(s)
  山﨑奈都、大橋礼、大橋里帆、水本秀二、山下匡、菅原明、山田修平
- Organizer
  第86回日本生化学会中部支部例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-21K06552
[Presentation] グリコサミノグリカンの結合領域四糖の生合成に関わるb3galt6をノックアウトしたゼブラフィッシュの機能解析2022
- Author(s)
  水本秀二、Sarah Delbaere、Adelbert De Clercq、Fredrik Noborn、Jan Willem Bek、Lien Alluyn、Charlotte Gistelinck、Delfien Syx、Phil L. Salmon、Paul J. Coucke、Goran Larson、山田修平、Andy Willaert、Fransiska Malfait
- Organizer
  糖鎖科学中部拠点　第17回若手の力フォーラム
- Data Source
  KAKENHI-PROJECT-21K06552
[Presentation] 興奮性神経特異的にヘパラン硫酸生合成酵素Extl3を欠損させたマウスの解析2022
- Author(s)
  三河範花、小林素子、石崎愛弓、髙羽里佳、衣斐大祐、水本秀二、平松正行、菅原明、山田修平
- Organizer
  第54回日本結合組織学術大会
- Data Source
  KAKENHI-PROJECT-21K06552
[Presentation] グリコサミノグリカンの結合領域四糖の生合成に関わるb3galt6をノックアウトしたゼブラフィッシュの機能解析2022
- Author(s)
  水本秀二, Sarah Delbaere, Adelbert De Clercq, Fredrik Noborn, Jan Willem Bek, Lien Alluyn, Charlotte Gistelinck, Delfien Syx, Phil L. Salmon, Paul J. Coucke, Goran Larson, 山田修平, Andy Willaert, Fransiska Malfait
- Organizer
  糖鎖科学中部拠点　第17回若手の力フォーラム、岐阜、1/13
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] 遺伝性の骨系統疾患を引き起こす変異型キシロース転移酵素の酵素活性への影響2022
- Author(s)
  水本秀二、清益慎也、山田修平
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06552
[Presentation] β3ガラクトース転移酵素6 (b3galt6) のゼブラフィッシュ変異体におけるコンドロイチン/デルマタン/ヘパラン硫酸の定量解析2022
- Author(s)
  水本秀二、Sarah Delbaere、Adelbert De Clercq、Fredrik Noborn、Jan Willem Bek、Lien Alluyn、Charlotte Gistelinck、Delfien Syx、Phil L. Salmon、Paul J. Coucke、Goran Larson、山田修平、Andy Willaert、Fransiska Malfait
- Organizer
  日本薬学会第142回年会
- Data Source
  KAKENHI-PROJECT-21K06552
[Presentation] Chst14 KOマウスを用いた筋拘縮型エーラス・ダンロス症候群の皮膚病態の解析と治療法探索2022
- Author(s)
  吉沢隆浩、高橋有希、小野史子、嶋田新、岳鳳鳴、水本秀二、山田修平、古庄知己
- Organizer
  第3回日本エーラス・ダンロス症候群(EDS)研究会
- Data Source
  KAKENHI-PROJECT-19K08745
[Presentation] ヘパラン硫酸生合成酵素Extl3を興奮性神経特異的に欠損させたマウスにおける認知機能と不安様行動の解析2022
- Author(s)
  三河範花、髙羽里佳、小林素子、石崎愛弓、衣斐大祐、水本秀二、平松正行、菅原明、山田修平
- Organizer
  日本薬学会第142回年会
- Data Source
  KAKENHI-PROJECT-21K06552
[Presentation] 疾患モデルマウスを用いた筋拘縮型エーラス・ダンロス症候群の包括的骨病変解析2022
- Author(s)
  高橋有希、吉沢隆浩、水本秀二、上原将志、渡邉敬文、小野史子、嶋田新、山田修平、高橋淳、古庄知己
- Organizer
  第3回日本エーラス・ダンロス症候群(EDS)研究会
- Data Source
  KAKENHI-PROJECT-19K08745
[Presentation] グリコサミノグリカンの結合領域四糖の生合成に関わるb3galt6をノックアウトしたゼブラフィッシュにおけるコンドロイチン/デルマタン/ヘパラン硫酸の定量解析2021
- Author(s)
  Sarah Delbaere、Adelbert De Clercq、水本秀二、Fredrik Noborn、Jan Willem Bek、Lien Alluyn、Charlotte Gistelinck、Delfien Syx、Phil L. Salmon、Paul J. Coucke、Goran Larson、山田修平、Andy Willaert、Fransiska Malfait
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06552
[Presentation] コンドロイチン/デルマタン/ヘパラン硫酸の結合領域四糖の生合成に関わるb3galt6のゼブラフィッシュ変異体におけるグリコサミノグリカンの定量2021
- Author(s)
  水本秀二、Sarah Delbaere，Adelbert De Clercq，Fredrik Noborn, Jan Willem Bek，Lien Alluyn，Charlotte Gistelinck，Delfien Syx，Phil L. Salmon，Paul J. Coucke，Goran Larson，山田修平，Andy Willaert，Fransiska Malfait
- Organizer
  第40回日本糖質学会年会、鹿児島、10/28
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] カルシウム活性型ヌクレオチダーゼ1(CANT1)とβ3グルクロン酸転移酵素3(B3GAT3)の機能喪失型変異は偽性捻曲性骨異形成症を引き起こす2021
- Author(s)
  水本秀二、Alicia B Byrne、Peer Arts、Patrick Yap、Jinghua Feng、Andreas W Schreiber、Milena Babic、Sarah L King-Smith、Christopher P Barnett、Lynette Moore、菅原一幸、Hatice Mutlu-Albayrak、西村玄、Jan E Liebelt、山田修平、Ravi Savarirayan、Hamish S Scott
- Organizer
  日本薬学会第141回年会、広島、3/27
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] グリコサミノグリカンの生合成に関わるb3galt6をノックアウトしたゼブラフィッシュにおけるグリコサミノグリカンの定量解析2021
- Author(s)
  Sarah Delbaere、Adelbert De Clercq、水本秀二、Fredrik Noborn、Jan Willem Bek、Lien Alluyn、Charlotte Gistelinck、Delfien Syx、Phil L. Salmon、Paul J. Coucke、Goran Larson、山田修平、Andy Willaert、Fransiska Malfait
- Organizer
  第85回日本生化学会中部支部例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-21K06552
[Presentation] グリコサミノグリカンの結合領域四糖の生合成に関わるb3galt6をノックアウトしたゼブラフィッシュにおけるコンドロイチン/デルマタン/ヘパラン硫酸の定量解析2021
- Author(s)
  Sarah Delbaere，Adelbert De Clercq，水本秀二、Fredrik Noborn, Jan Willem Bek，Lien Alluyn，Charlotte Gistelinck，Delfien Syx，Phil L. Salmon，Paul J. Coucke，Goan Larson，山田修平，Andy Willaert，Fransiska Malfait
- Organizer
  第94回日本生化学会大会、横浜、11/3
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] コンドロイチン/デルマタン/ヘパラン硫酸の結合領域四糖の生合成に関わるb3galt6のゼブラフィッシュ変異体におけるグリコサミノグリカンの定量2021
- Author(s)
  水本秀二、Sarah Delbaere、Adelbert De Clercq、Fredrik Noborn、Jan Willem Bek、Lien Alluyn、Charlotte Gistelinck、Delfien Syx、Phil L. Salmon、Paul J. Coucke、Goran Larson、山田修平、Andy Willaert、Fransiska Malfait
- Organizer
  第40回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-21K06552
[Presentation] 前脳領域の興奮性神経特異的Extl3欠損マウスの認知機能解析2021
- Author(s)
  小林素子、石崎愛弓、髙羽里佳、衣斐大祐、水本秀二、平松正行、菅原明、山田修平
- Organizer
  第67回日本薬学会東海支部総会・大会
- Data Source
  KAKENHI-PROJECT-21K06552
[Presentation] グリコサミノグリカンの結合領域四糖(GlcA-Gal-Gal-Xyl)の生合成に関わるb3galt6を欠損したゼブラフィッシュにおけるグリコサミノグリカンの定量解析2021
- Author(s)
  Sarah Delbaere、Adelbert De Clercq、水本秀二、Fredrik Noborn、Jan Willem Bek、Lien Alluyn、Charlotte Gistelinck、Delfien Syx、Phil L. Salmon、Paul J. Coucke、Goran Larson、山田修平、Andy Willaert、Fransiska Malfait
- Organizer
  第53回日本結合組織学術大会
- Data Source
  KAKENHI-PROJECT-21K06552
[Presentation] 1歳齢の疾患モデルマウス(Chst14-/-)を用いた筋拘縮型エーラス・ダンロス症候群(mcEDS)の骨病変の解析2021
- Author(s)
  高橋有希、吉沢隆浩、水本秀二、山田修平、古庄知己
- Organizer
  日本人類遺伝学会第66回大会
- Data Source
  KAKENHI-PROJECT-19H03616
[Presentation] グリコサミノグリカンの生合成に関わるキシロース転移酵素の活性低下が引き起こす遺伝性骨系統疾患2021
- Author(s)
  花立妃子、伊藤有美、山田修平、水本秀二
- Organizer
  第53回日本結合組織学術大会
- Data Source
  KAKENHI-PROJECT-21K06552
[Presentation] Pathogenic variants in uridine diphosphate nucleotidase (CANT1) or glucuronyltransferase (B3GAT3) causes a pseudodiastrophic dysplasia2021
- Author(s)
  Shuji Mizumoto, Alicia B Byrne, Kazuyuki Sugahara, Shuhei Yamada, Hamish S Scott
- Organizer
  2021 ASBMB Annual Meeting, Athens, 4/29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] T細胞特異的Extl3欠損マウスの作製とその解析2021
- Author(s)
  大橋礼、大橋里帆、水本秀二、山下匡、菅原明、山田修平
- Organizer
  第67回日本薬学会東海支部総会・大会
- Data Source
  KAKENHI-PROJECT-21K06552
[Presentation] 脊椎異形成型エーラス・ダンロス症候群のゼブラフィッシュモデル2021
- Author(s)
  水本秀二, Sarah Delbaere, Adelbert De Clercq, Fredrik Noborn, Jan Willem Bek, Lien Alluyn, Charlotte Gistelinck, Delfien Syx, Phil L. Salmon, Paul J. Coucke, Goran Larson, 山田修平, Andy Willaert, Fransiska Malfait
- Organizer
  第2回日本エーラス・ダンロス研究会、栃木、12/11
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] 糖鎖の生合成異常による遺伝性の骨・関節・皮膚疾患2021
- Author(s)
  水本秀二
- Organizer
  名城大学リサーチフェア2021 シンポジウム「難病の治療・予防を目指した病因・病態のメカニズム解明　～難治性疾患発症メカニズム研究センターの活動～」
- Data Source
  KAKENHI-PROJECT-19H03616
[Presentation] ウリジン二リン酸ヌクレオチダーゼあるいはグルクロン酸転移酵素-Iの変異による偽性捻曲性骨異形成症2021
- Author(s)
  水本秀二、Alicia B Byrne、Peer Arts、Patrick Yap、Jinghua Feng、Andreas W Schreiber、Milena Babic、Sarah L King-Smith、Christopher P Barnett、Lynette Moore、菅原一幸、Hatice Mutlu-Albayrak、西村玄、Jan E Liebelt、山田修平、Ravi Savarirayan、Hamish S Scott
- Organizer
  糖鎖科学中部拠点　第16回若手の力フォーラム、名古屋、1/22
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] グリコサミノグリカンの生合成に関わるキシロース転移酵素の活性低下が引き起こす遺伝性骨系統疾患2021
- Author(s)
  花立妃子、伊藤有美、山田修平、水本秀二
- Organizer
  第53回日本結合組織学術大会、東京、6/26
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] 前脳領域の興奮性神経特異的Extl3欠損マウスの作製とその行動観察2021
- Author(s)
  石崎愛弓、小林素子、髙羽里佳、衣斐大祐、水本秀二、平松正行、菅原明、山田修平
- Organizer
  第67回日本薬学会東海支部総会・大会
- Data Source
  KAKENHI-PROJECT-21K06552
[Presentation] グリコサミノグリカンの結合領域四糖の生合成に関わるb3galt6をノックアウトしたゼブラフィッシュにおける骨・皮膚・筋肉の解析2021
- Author(s)
  Sarah Delbaere、Adelbert De Clercq、水本秀二、Fredrik Noborn、Jan Willem Bek、Lien Alluyn、Charlotte Gistelinck、Delfien Syx、Phil L. Salmon、Paul J. Coucke、Goran Larson、山田修平、Andy Willaert、Fransiska Malfait
- Organizer
  第44回日本分子生物学会大会
- Data Source
  KAKENHI-PROJECT-21K06552
[Presentation] グリコサミノグリカンの生合成に関わるb3galt6をノックアウトしたゼブラフィッシュにおけるグリコサミノグリカンの定量解析2021
- Author(s)
  Sarah Delbaere，Adelbert De Clercq，水本秀二，Fredrik Noborn, Jan Willem Bek，Lien Alluyn，Charlotte Gistelinck，Delfien Syx，Phil L. Salmon，Paul J. Coucke，Goran Larson，山田修平，Andy Willaert，Fransiska Malfait
- Organizer
  第85回日本生化学会中部支部例会・シンポジウム、静岡、5/22
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] 1歳齢の疾患モデルマウス(Chst14-/-)を用いた筋拘縮型エーラス・ダンロス症候群(mcEDS)の骨病変の解析2021
- Author(s)
  高橋有希、吉沢隆浩、水本秀二、山田修平、古庄知己
- Organizer
  日本人類遺伝学会第66回大会
- Data Source
  KAKENHI-PROJECT-19K08745
[Presentation] 疾患モデルマウスを用いた筋拘縮型エーラス・ダンロス症候群（mcEDS）の骨病変解析2021
- Author(s)
  高橋有希、吉沢隆浩、水本秀二、山田修平、古庄知己
- Organizer
  第2回日本エーラス・ダンロス研究会
- Data Source
  KAKENHI-PROJECT-19H03616
[Presentation] グリコサミノグリカンの結合領域四糖(GlcA-Gal-Gal-Xyl)の生合成に関わるb3galt6を欠損したゼブラフィッシュにおけるグリコサミノグリカンの定量解析2021
- Author(s)
  Sarah Delbaere，Adelbert De Clercq，水本秀二，Fredrik Noborn, Jan Willem Bek，Lien Alluyn，Charlotte Gistelinck，Delfien Syx，Phil L. Salmon，Paul J. Coucke，Goran Larson，山田修平，Andy Willaert，Fransiska Malfait
- Organizer
  第53回日本結合組織学術大会、東京、6/26
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] グリコサミノグリカンの結合領域四糖の生合成に関わるb3galt6をノックアウトしたゼブラフィッシュにおける骨・皮膚・筋肉の解析2021
- Author(s)
  Sarah Delbaere，Adelbert De Clercq，水本秀二、Fredrik Noborn, Jan Willem Bek，Lien Alluyn，Charlotte Gistelinck，Delfien Syx，Phil L. Salmon，Paul J. Coucke，Goran Larson，山田修平，Andy Willaert，Fransiska Malfait
- Organizer
  第44回日本分子生物学会大会、横浜、12/1
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] 筋拘縮型エーラスダンロス症候群の疾患モデル動物としてのChst14遺伝子欠損マウスの解析(Analysis of Chst14 Knockout Mice as an Animal Model of Musculocontractural Ehlers-Danlos Syndrome)2020
- Author(s)
  吉沢隆浩、嶋田新、高橋有希、水本秀二、山田修平、山中仁木、古庄知己、松本清司
- Organizer
  第67回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-19K08745
[Presentation] グリコサミノグリカンの生合成異常による遺伝性の骨・皮膚疾患2020
- Author(s)
  水本秀二
- Organizer
  第52回日本結合組織学術大会、大府、9/19
- Invited
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] 遺伝性の骨系統疾患を引き起こすキシロース転移酵素のアミノ酸変異による酵素活性への影響2020
- Author(s)
  伊藤有美, 山田修平, 水本秀二
- Organizer
  日本薬学会第140回年会、京都、3/26
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] グリコサミノグリカンの生合成異常による遺伝性の骨・皮膚疾患2020
- Author(s)
  水本秀二
- Organizer
  第52回日本結合組織学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03616
[Presentation] 筋拘縮型エーラス・ダンロス症候群(mcEDS)の皮膚症状の疾患モデルマウスの開発2020
- Author(s)
  吉沢隆浩、高橋有希、岳鳳鳴、水本秀二、山田修平、古庄知己
- Organizer
  第1回日本エーラス・ダンロス研究会
- Data Source
  KAKENHI-PROJECT-19H03616
[Presentation] 筋拘縮型エーラス・ダンロス症候群（mcEDS）の疾患モデルマウス（Chst14-/-）を用いた骨の表現型解析2020
- Author(s)
  高橋有希、吉沢隆浩、水本秀二、山田修平、古庄知己
- Organizer
  第1回日本エーラス・ダンロス研究
- Data Source
  KAKENHI-PROJECT-19H03616
[Presentation] The role of glycosaminoglycans and their degrading enzymes in inflammatory cell homeostasis2020
- Author(s)
  Brooke L. Farrugia, Shuji Mizumoto, Megan S. Lord, Shuhei Yamada, and John M. Whitelock
- Organizer
  12th Pan Pacific Connective Tissue Societies Symposium 2020, Melbourne (Australia), 11/26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] A skeletal dysplasia with advanced bone age is caused by pathogenic variants in CSGALNACT12020
- Author(s)
  Shuji Mizumoto, Andreas R. Janecke, Azita Sadeghpour, Gundula Povysil, Marie T. McDonald, Sheila Unger, Susanne Greber-Platzer, Nicholas Katsanis, Andrea Superti-Furga, Kazuyuki Sugahara, Erica E. Davis, Shuhei Yamada, Julia Vodopiutz
- Organizer
  12th Pan Pacific Connective Tissue Societies Symposium 2020, Melbourne (Australia), 11/24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] コンドロイチン硫酸修飾デコリンを用いた筋拘縮型エーラス・ダンロス症候群の診断法の開発2020
- Author(s)
  山田和夫、Gong Ao、古庄知己、水本秀二、山田修平、竹下治男、松本健一
- Organizer
  第1回日本エーラス・ダンロス研究
- Data Source
  KAKENHI-PROJECT-19H03616
[Presentation] デルマタン硫酸の生合成異常によるエーラス・ダンロス症候群における糖鎖生化学的解析2020
- Author(s)
  水本秀二、山田修平
- Organizer
  第１回日本エーラス・ダンロス研究会、松本、12/12
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] CSGALNACT1の機能喪失型の変異は骨異形成症を引き起こす2020
- Author(s)
  水本秀二, Andreas R. Janecke, Azita Sadeghpour, Gundula Povysil, Marie T. McDonald, Sheila Unger, Susanne Greber-Platzer, Nicholas Katsanis, Andrea Superti-Furga, 菅原一幸, Erica E. Davis, 山田修平, Julia Vodopiutz
- Organizer
  日本薬学会第140回年会、京都、3/28
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] 偽性捻曲性骨異形成症はグルクロン酸転移酵素-Iおよびウリジン二リン酸ヌクレオチダーゼの変異によって発症する2020
- Author(s)
  水本秀二, Alicia B Byrne, Peer Arts, Patrick Yap, Jinghua Feng, Andreas W Schreiber, Milena Babic, Sarah L King-Smith, Christopher P Barnett, Lynette Moore, 菅原一幸, Hatice Mutlu-Albayrak, Gen Nishimura, Jan E Liebelt, 山田修平, Ravi Savarirayan, Hamish S Scott
- Organizer
  第93回日本生化学会大会、横浜、9/14
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] グルクロン酸転移酵素-Iおよびウリジン二リン酸ヌクレオチダーゼの変異による偽性捻曲性骨異形成症2020
- Author(s)
  水本秀二, Alicia B Byrne, Peer Arts, Patrick Yap, Jinghua Feng, Andreas W Schreiber, Milena Babic, Sarah L King-Smith, Christopher P Barnett, Lynette Moore, 菅原一幸, Hatice Mutlu-Albayrak, Gen Nishimura, Jan E Liebelt, 山田修平, Ravi Savarirayan, Hamish S Scott
- Organizer
  第84回日本生化学会中部支部例会・シンポジウム、名古屋、5/24
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] A pseudodiastrophic dysplasia is caused by pathogenic variants in calcium-activated nucleotidase-1 and glucuronyltransferase-I2020
- Author(s)
  Shuji Mizumoto, Alicia B Byrne, Kazuyuki Sugahara, Shuhei Yamada, Hamish S Scott
- Organizer
  2020 Annual Meeting of the Society for Glycobiology, U.S.A., 11/9
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] Pathogenic variants in glucuronyltransferase-I and calcium-activated nucleotidase-1 cause pseudodiastrophic dysplasia2020
- Author(s)
  Shuji Mizumoto, Alicia B Byrne, Peer Arts, Patrick Yap, Jinghua Feng, Andreas W Schreiber, Milena Babic, Sarah L King-Smith, Christopher P Barnett, Lynette Moore, Kazuyuki Sugahara, Hatice Mutlu-Albayrak, Gen Nishimura, Jan E Liebelt, Shuhei Yamada, Ravi Savarirayan, Hamish S Scott
- Organizer
  12th International Symposium on Glycosyltransferases (GlycoT2020), Boston (U.S.A.), 6/21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] CRISPR/Cas9を用いて作成した筋拘縮型エーラス・ダンロス症候群モデルマウスの表現型2020
- Author(s)
  笠原優子、積田奈々、水本秀二、井上（上野）由紀子、井上高良、髙橋（中村）有希、吉沢隆浩、髙橋有希、宮田真路、山田修平、武田伸一、渡邉淳、野村義宏、古庄知己、岡田尚巳
- Organizer
  第1回日本エーラス・ダンロス研究
- Data Source
  KAKENHI-PROJECT-19H03616
[Presentation] コンドロイチン修飾デコリンを用いた筋拘縮型エーラス・ダンロス症候群の診断法の開発2020
- Author(s)
  山田和夫、Ao Gong、古庄知己、水本秀二、山田修平、竹下治男、松本健一
- Organizer
  第52回日本結合組織学術大会
- Data Source
  KAKENHI-PROJECT-19H03616
[Presentation] 筋拘縮型エーラス・ダンロス症候群（mcEDS）の疾患モデルマウス (Chst14-/-) を用いた骨の表現型解析2020
- Author(s)
  高橋有希、吉沢隆浩、水本秀二、山田修平、古庄知己
- Organizer
  第52回日本結合組織学術大会
- Data Source
  KAKENHI-PROJECT-19H03616
[Presentation] 疾患モデルマウス（Chst14-/-）を用いた筋拘縮型エーラス・ダンロス症候群（mcEDS）の骨病変の解析2020
- Author(s)
  高橋有希、吉沢隆浩、水本秀二、山田修平、古庄知己
- Organizer
  日本人類遺伝学会第65回大会
- Data Source
  KAKENHI-PROJECT-19H03616
[Presentation] UDPヌクレオチダーゼおよびGlcAT-Iの変異は偽性捻曲性骨異形成症を発症する2020
- Author(s)
  水本秀二、Alicia B Byrne、Peer Arts、Patrick Yap、Jinghua Feng、Andreas W Schreiber、Milena Babic、Sarah L King-Smith、Christopher P Barnett、Lynette Moore、菅原一幸、Hatice Mutlu-Albayrak、西村玄、Jan E Liebelt、山田修平、Ravi Savarirayan、Hamish S Scott
- Organizer
  第39回日本糖質学会年会、東京、11/21
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] 筋拘縮型エーラスダンロス症候群の疾患モデル動物としてのChst14遺伝子欠損マウスの解析2020
- Author(s)
  吉沢隆浩、嶋田新、高橋有希、水本秀二、山田修平、山中仁木、古庄知己、松本清司
- Organizer
  第67回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-19H03616
[Presentation] Biallelic loss-of-function mutations in CSGALNACT1 cause a skeletal dysplasia with advanced bone age2019
- Author(s)
  Shuji Mizumoto, Andreas R. Janecke, Azita Sadeghpour, Gundula Povysil, Marie T. McDonald, Sheila Unger, Susanne Greber-Platzer, Task Force for Neonatal Genomics, Nicholas Katsanis, Andrea Superti-Furga, Kazuyuki Sugahara, Erica E. Davis, Shuhei Yamada, Julia Vodopiutz
- Organizer
  43rd Human Genetics Society of Australasia Annual Scientific Meeting (HGSA2019), Wellington, New Zealand, 8/4
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] Chst14遺伝子欠損マウスを用いた筋拘縮型エーラスダンロス症候群(mcEDS)の血管・皮膚症状の病態解析2019
- Author(s)
  吉沢隆浩、嶋田新、高橋有希、水本秀二、山田修平、古庄知己
- Organizer
  日本人類遺伝学会第64回大会、長崎、11/8
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] Proteoglycan defect-related EDS2019
- Author(s)
  Shuji Mizumoto
- Organizer
  Scientific Meeting on The Rare Types of Ehlers-Danlos Syndromes, Tokyo, 11/19
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] プロテオグリカン糖側鎖の生合成不全に起因する遺伝性の骨・関節・皮膚・心臓・免疫・神経疾患2019
- Author(s)
  水本秀二
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03616
[Presentation] Clinical, biochemical, and pathological investigation of a patient with musculocontractural Ehlers-Danlos syndrome caused by a novel pathogenic variant in DSE2019
- Author(s)
  Mari Minatogawa, Shuji Mizumoto, Takuya Hirose, Tomomi Yamaguchi, Keiko Wakui, Takafumi Watanabe, Shuhei Yamada, Tomoki Kosho
- Organizer
  American Society of Human Genetics (ASHG) 2019, Huston, U.S.A., 10/16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] 脊椎骨端骨幹端異形成症患者のリンパ芽球様細胞株の産生するヘパラン硫酸の解析2019
- Author(s)
  佐藤亨、水本秀二、大橋博文、逆井悦子、Nursel H Elcioglu、三宅紀子、松本直通、池川志郎、山田修平
- Organizer
  第38回日本糖質学会年会、名古屋、8/20
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] 新規DSE変異による筋拘縮型エーラスダンロス症候群の日本人第1例における臨床的・糖鎖医学的・病理学的特徴2019
- Author(s)
  湊川真理、水本秀二、広瀬拓哉、山口智美、長江千愛、瀧正志、涌井敬子、渡邉敬文、山田修平、古庄知己
- Organizer
  日本人類遺伝学会第64回大会、長崎、11/8
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] Loss of galactosyltransferase II, encoded by b3galt6, causes musculoskeletal abnormalities in a zebrafish model for spondylodysplastic Ehlers-Danlos syndrome and reveals the presence of a trisaccharide proteoglycan linker region2019
- Author(s)
  Sarah Delbaere, Shuji Mizumoto, Shuhei Yamada, Fredrik Noborn, Goran Larson, Jan Willem Bek, Phil L. Salmon, Paul Coucke, Andy Willaert, Fransiska Malfait
- Organizer
  11th international Conference on Proteoglyans, Kanazawa, 10/2
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] Lunatic Fringe (LFNG)の機能喪失変異による脊椎肋骨異骨症2019
- Author(s)
  水本秀二, 武田和樹, 大伴直央, 山田修平, 池川志郎
- Organizer
  日本生化学会中部支部第82回例会・シンポジウム、名古屋、5/25
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] CRISPR/Cas9-mediated development and characterization of knockout mice for musculocontractural type Ehlers-Danlos Syndrome caused by mutations in CHST14 (mcEDS-CHST14).2019
- Author(s)
  Nitahara-Kasahara Y, Tsumita N, Mizumoto S, Inoue Y, Inoue T, Yoshizawa T, Takahashi Y, Guillermo PH, Oda Y, Nakamura-Takahashi A, Hashimoto A, Nomura Y, Takeda S, Watanabe A, Kosho T, Okada T
- Organizer
  Scientific Meeting on The Rare Types of Ehlers-Danlos Syndromes
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03616
[Presentation] Analysis of heparan sulfate produced by lymphoblastoid cell lines in patients with spondylo-epi-metaphyseal dysplasia2019
- Author(s)
  Toru Sato, Shuji Mizumoto, Hirofumi Ohashi, Etsuko Sakasai, Nursel H Elcioglu, Noriko Miyake, Naomichi Matsumoto, Shiro Ikegawa, Shuhei Yamada
- Organizer
  11th international Conference on Proteoglyans, Kanazawa, 9/30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] Chst14遺伝子欠損マウスを用いた筋拘縮型エーラスダンロス症候群(mcEDS)の血管・皮膚症状の病態解析2019
- Author(s)
  吉沢隆浩、嶋田新、高橋有希、水本秀二、山田修平、古庄知己
- Organizer
  日本人類遺伝学会第64回大会
- Data Source
  KAKENHI-PROJECT-19H03616
[Presentation] Human mast cells produce hyaluronidase 1 and 4, that cleaves chondroitin sulfate chains that decorate serglycin2019
- Author(s)
  Brooke Farrugia, Shuji Mizumoto, Megan Lord, Shuhei Yamada, John Whitelock
- Organizer
  11th international Conference on Proteoglyans, Kanazawa, 9/30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] Paternal Isodisomy and Blended Phenotypes: A Pediatric Case with Mosaic Trisomy 8 and a Homozygous CSGALNACT1 Missense Variant2019
- Author(s)
  Azita Sadeghpour, J. K. Holsclaw, M. T. McDonald, W. B. Gallentine, J. Vodopiutz, A. R. Janecke, S. Yamada, S. Mizumoto, E. E. Davis , N. Katsanis, Task Force for Neonatal Genomics
- Organizer
  American College of Medical Genetics and Genomics (ACMG) Annual Clinical Genetics Meeting, Seattle, U.S.A., 4/6
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] Skin and Vascular Abnormalities in Chst14 Gene-Deleted Mice, an Animal Model of Musculocontractual Ehlers-Danlos Syndrome2019
- Author(s)
  Yoshizawa T, Mizumoto S, Takahashi Y, Shimada S, Sugahara K, Nakayama J, Takeda S, Nomura Y, Nitahara-Kasahara Y, Okada T, Matsumoto K, Yamada S, Kosho T
- Organizer
  Scientific Meeting on The Rare Types of Ehlers-Danlos Syndromes
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03616
[Presentation] Two types of heparan sulfate clusters differently regulate Wnt distribution and signaling in Xenopus embryos2019
- Author(s)
  Yusuke Mii, Takayoshi Yamamoto, Ritsuko Takada, Shuji Mizumoto, Makoto Matsuyama, Shuhei Yamada, Masanori Taira, Shinji Takada
- Organizer
  11th international Conference on Proteoglyans, Kanazawa, 10/1
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] プロテオグリカン糖側鎖の生合成不全に起因する遺伝性の骨・関節・皮膚・心臓・免疫・神経疾患2019
- Author(s)
  水本秀二
- Organizer
  第92回日本生化学会大会、横浜、9/18
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] Human mast cells produce the mammalian chondroitinase, hyaluronidase 42019
- Author(s)
  Brooke L. Farrugia, Shuji Mizumoto, Megan S. Lord, Shuhei Yamada, and John M. Whitelock
- Organizer
  9th EMBRN International Mast Cell and Basophil Meeting / A Marcus Wallenberg symposium, Uppsala, Sweden, 6/17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] コンドロイチン硫酸の生合成を担うCSGALNACT1の変異は骨異形成症を発症する2019
- Author(s)
  水本秀二, Andreas R. Janecke, Azita Sadeghpour, Gundula Povysil, Marie T. McDonald, Sheila Unger, Susanne Greber-Platzer, Nicholas Katsanis, Andrea Superti-Furga, 菅原一幸, Erica E. Davis, 山田修平, Julia Vodopiutz
- Organizer
  第38回日本糖質学会年会、名古屋、8/21
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] Skin and Vascular Abnormalities in Chst14 Gene-Deleted Mice, an Animal Model of Musculocontractual Ehlers-Danlos Syndrome2019
- Author(s)
  Takahiro Yoshizawa, Shuji Mizumoto, Yuki Takahashi, Shin Shimada, Kazuyuki Sugahara, Jun Nakayama, Shin’ichi Takeda, Yoshihiro Nomura, Yuko Nitahara-Kasahara, Takashi Okada, Kiyoshi Matsumoto, Shuhei Yamada, Tomoki Kosho
- Organizer
  The Ehlers-Danlos Society , Scientific Meeting on the Rarer Types of Ehlers-Danlos Syndromes 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08745
[Presentation] Chst14遺伝子欠損マウスを用いた筋拘縮型エーラスダンロス症候群(mcEDS)の血管・皮膚症状の病態解析(Skin and Vascular Abnormalities in Chst14 Knockout Mice, an Animal Model of Musculocontractural Ehlers-Danlos Syndrome)2019
- Author(s)
  吉沢隆浩、嶋田新、高橋有希、水本秀二、山田修平、古庄知己
- Organizer
  日本人類遺伝学会 , 日本人類遺伝学会第64回大会
- Data Source
  KAKENHI-PROJECT-19K08745
[Presentation] Clinical, biochemical, and pathological investigation of a patient with musculocontractural Ehlers-Danlos syndrome caused by a novel pathogenic variant in DSE2019
- Author(s)
  Minatogawa M, Mizumoto S, Hirose T, Yamaguchi T, Wakui K, Watanabe T, Yamada S, Kosho T.
- Organizer
  American Society of Human Genetics, Annual Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03616
[Presentation] A skeletal dysplasia with joint laxity and advanced bone age is caused by loss-of-function mutations in CSGALNACT12019
- Author(s)
  Shuji Mizumoto, Andreas R. Janecke, Azita Sadeghpour, Erica E. Davis, Kazuyuki Sugahara, Shuhei Yamada, Julia Vodopiutz
- Organizer
  11th international Conference on Proteoglyans, Kanazawa, 9/30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] Loss of galactosyltransferase II, encoded by b3galt6, causes musculoskeletal abnormalities in a zebrafish model for spondylodysplastic Ehlers-Danlos syndrome and reveals the presence of a trisaccharide proteoglycan linker region2019
- Author(s)
  Sarah Delbaere, Shuji Mizumoto, Shuhei Yamada, Fredrik Noborn, Goran Larson, Jan Willem Bek, Phil L. Salmon, Paul Coucke, Andy Willaert, Fransiska Malfait
- Organizer
  Proteoglycans Future Leaders Symposium 2019, Kanazawa, 9/29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] Defects in biosynthesis of glycosaminoglycan side chains of proteoglycans cause hereditary bone, skin, heart, and immune disorders2019
- Author(s)
  Mizumoto S
- Organizer
  Proteoglycans Future Leaders Symposium 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03616
[Presentation] Defects in biosynthesis of glycosaminoglycan side chains of proteoglycans cause hereditary bone, skin, heart, and immune disorders2019
- Author(s)
  Shuji Mizumoto
- Organizer
  Proteoglycans Future Leaders Symposium 2019, Kanazawa, 9/29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] Two types of heparan sulfate clusters differently regulate Wnt distribution and signaling in Xenopus embryos2019
- Author(s)
  Yusuke Mii, Takayoshi Yamamoto, Ritsuko Takada, Shuji Mizumoto, Makoto Matsuyama, Shuhei Yamada, Masanori Taira, Shinji Takada
- Organizer
  Proteoglycans Future Leaders Symposium 2019, Kanazawa, 9/29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07054
[Presentation] Proteoglycan defect-related EDS2019
- Author(s)
  Mizumoto S
- Organizer
  Scientific Meeting on The Rare Types of Ehlers-Danlos Syndromes
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03616
[Presentation] リンパ芽球様細胞株の産生するグリコサミノグリカンの解析2018
- Author(s)
  篠田はるか、持永磨奈美、伊藤有沙、水本秀二、逆井悦子、大橋博文、山田修平
- Organizer
  第64回日本薬学会東海支部総会・大会、名古屋、6/30
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] ナノ液体クロマトグラフィータンデム質量分析法を用いたエーラス・ダンロス症候群の診断法の開発2018
- Author(s)
  山田和夫、渡辺淳、古庄知己、水本秀二、山田修平、竹下治男、松本健一
- Organizer
  第50回日本結合組織学会学術大会、福岡、6/30
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] ヘパラン硫酸の生合成を担うEXTL3の変異は免疫不全を伴う脊椎骨端骨幹端異形成症を引き起こす2018
- Author(s)
  水本秀二, Long Guo, Nursel H Elcioglu, Zheng Wang, Bilge Noyan, Hatice M Albayrak, 松本直通, 三宅紀子, 西村玄, 山田修平, 池川志郎
- Organizer
  糖鎖科学中部拠点　第15回若手の力フォーラム、静岡、9/6
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] 平成30年度日本薬学会東海支部学術奨励賞受賞講演「グリコサミノグリカンの生合成異常による骨・皮膚疾患の糖鎖解析と癌転移における役割」2018
- Author(s)
  水本秀二
- Organizer
  第64回日本薬学会東海支部総会・大会、名古屋、6/30
- Invited
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] 骨・関節疾患におけるコンドロイチン硫酸/デルマタン硫酸の役割2018
- Author(s)
  水本秀二
- Organizer
  日本薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2018、静岡、11/4
- Invited
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] Pathophysiological investigation of musculocontractural EDS caused by mutations in CHST14 using knock-out mice2018
- Author(s)
  Takahiro Yoshizawa, Shuji Mizumoto, Yuki Takahashi, Shin Shimada, Kazuyuki Sugahara, Jun Nakayama, Shin’ichi Takeda, Yoshihiro Nomura, Yuko Nitahara-Kasahara, Takashi Okada, Kiyoshi Matsumoto, Shuhei Yamada, Tomoki Kosho
- Organizer
  The International Symposium on the Ehlers-Danlos Syndromes (EDS2018),Ghent, Belgium, 9/28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] A mouse model for gerodermia osteodysplastica, Gorab-null mice, shows a reduction in glycosaminoglycans2018
- Author(s)
  Wing Lee Chan, Magdalena Steiner Tomasz Witkos, Johannes Egerer, Bjorn Busse, Shuji Mizumoto, et al.
- Organizer
  第91回日本生化学会大会、京都、9/24
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] Structural alteration of glycosaminoglycan side chains and spatial disorganization of collagen networks in the skin of patients with musculocontractural Ehlers-Danlos syndrome caused by CHST14/D4ST1 deficiency2018
- Author(s)
  Tomoki Kosho, Takuya Hirose, Naoki Takahashi, Prasarn Tangkawattana, Jun Minaguchi, Shuji Mizumoto Shuhei Yamada; Noriko Miyake, Atsushi Hatamochi, Jun Nakayama, Tomomi Yamaguchi, Kazushige Takehana
- Organizer
  American Society of Human Genetics (ASHG) 2018, San Diego, USA, 10/19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] Structural studies on heparan sulfate produced by the lymphoblastoid cell lines prepared from a patient with a mutation in EXTL3 and embryonic cells from Extl3-deficient mice2018
- Author(s)
  Shuhei Yamada, Shuji Mizumoto, Hirofumi Ohashi, Etsuko Sakasai, Nursel H Elcioglu, Noriko Miyake, Naomichi Matsumoto, Daisuke Ibi, Akira Sugawara, and Shiro Ikegawa
- Organizer
  Gordon Research Conference on Proteoglycans 2018, Andover, Poster, USA, 7/8-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] ヘパラン硫酸生合成酵素であるEXTL3の変異は免疫異常を伴う新たなタイプの脊椎骨端骨幹端異形成症を引き起こす2018
- Author(s)
  Long Guo, Nursel H Elcioglu, Shuji Mizumoto, Zheng Wang, Bilge Noyan, Hatice M Albayrak, Shuhei Yamada, Naomichi Matsumoto, Noriko Miyake, Gen Nishimura1, Shiro Ikegawa
- Organizer
  日本生化学会中部支部第82回例会・シンポジウム、岐阜、5/19
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] McEDS-CHST14患者におけるデコリン糖鎖変異のI型コラーゲン細線維形成に及ぼす影響2018
- Author(s)
  橋本綾菜、野村義宏、広瀬拓哉、竹花一成、美名口順、水本秀二、山田修平、古庄知己、笠原優子、岡田尚巳
- Organizer
  第50回日本結合組織学会学術大会、福岡、6/29
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] The mammalian chondroitinase, hyaluronidase 4, is produced by human mast cells: its role in modulating the structure of chondroitin sulfate and regulating tissue remodeling2018
- Author(s)
  Brooke L. Farrugia, Shuji Mizumoto, Megan S. Lord, James Melrose, Shuhei Yamada, Bruce Caterson, and John M. Whitelock
- Organizer
  Gordon Research Conference on Proteoglycans 2018, , Andover, Poster, USA, 7/8-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] ルイス肺がん細胞の腫瘍形成におけるRAGE欠損の影響2018
- Author(s)
  鈴木麻未、幸村省吾、水本秀二、菅原一幸、山田修平
- Organizer
  第64回日本薬学会東海支部総会・大会、名古屋、6/30
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] A novel type of spondylo-epi-metaphyseal dysplasia with immuno-deficiency caused by mutation in EXTL3 encoding a glycosyltransferase responsible for biosynthesis of heparan sulfate2018
- Author(s)
  Shuji Mizumoto, Long Guo, Nursel H Elcioglu, Zheng Wang, Bilge Noyan, Hatice M Albayrak, Naomichi Matsumoto, Noriko Miyake, Gen Nishimura, Shuhei Yamada, and Shiro Ikegawa
- Organizer
  The 11th International Symposium on Glycosyltransferases, Qingdao, China, 6/19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] 免疫異常を伴う脊椎骨端骨幹端異形成症はヘパラン硫酸の生合成を担うEXTL3の変異により引き起こされる2018
- Author(s)
  水本秀二, Long Guo, Nursel H Elcioglu, Zheng Wang, Bilge Noyan, Hatice M Albayrak,松本直通, 三宅紀子, 西村玄, 山田修平, 池川志郎
- Organizer
  第37回日本糖質学会年会、仙台、8/30
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] Musculocontractural Ehlers-Danlos syndrome caused by a CHST14 deficiency results in defect in urinary dermatan sulfate2018
- Author(s)
  Shuji Mizumoto, Tomoki Kosho, Atsushi Hatamochi, Tomoko Honda, Tomomi Yamaguchi, Nobuhiko Okamoto, Noriko Miyake, Kazuyuki Sugahara, Shuhei Yamada
- Organizer
  The International Symposium on the Ehlers-Danlos Syndromes (EDS2018),Ghent, Belgium, 9/27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] The mammalian chondroitinase, hyaluronidase 4, is produced by human mast cells and generates chondroitin sulfate cleavage neo-epitopes2018
- Author(s)
  Brooke Farrugia, Megan Lord, Shuji Mizumoto, Shuhei Yamada, Bruce Caterson, John Whitelock
- Organizer
  The AWTRS/MEPSA/ASDR Cutaneous Biology Meeting 2018, Brisbane, Australia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] Human mast cells produce the mammalian chondroitinase, hyaluronidase 4, and generate unique chondroitin sulphate structures2018
- Author(s)
  Brooke L. Farrugia, Shuji Mizumoto, Megan S. Lord, Shuhei Yamada, Bruce Caterson, and John M. Whitelock
- Organizer
  Matrix Biology Society of Australia and New Zealand, Annual Meeting 2018, Auckland, New Zealand, 12/6
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] 発生段階の異なるマウス脳におけるグリコサミノグリカン分解酵素の発現解析2017
- Author(s)
  禰津瑠里子、三輪一貴、水本秀二、山田修平
- Organizer
  第36回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] ヒアルロニダーゼ1および４の基質認識に関与するアミノ酸残基の解析2017
- Author(s)
  白水仁子、小林智恵里、稲葉史恵、安部優貴子、水本秀二、山田修平
- Organizer
  第36回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] Ehlers-Danlos syndrome caused by mutations in CHST14/D4ST1 results in defect of urinary dermatan sulfate2017
- Author(s)
  Shuji Mizumoto, ◯Shuhei Yamada, Tomoki Kosho, Atsushi Hatamochi, Tomoko Honda, Tomomi Yamaguchi, Nobuhiko Okamoto, Noriko Miyake, and Kazuyuki Sugahara
- Organizer
  7 Lakes Proteoglycans Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] Delineation of musculocontractural Ehles-Danlos syndrome caused by dermatan sulfate epimerase deficiency (mcEDS-DSE): report of additional patients and comprehensive review of reported cases2017
- Author(s)
  〇A. Unzaki, CK. Lautrup, K. Wee Teik, S. Mizumoto, H. Hock Sin, IK. Nielsen, S. Markholt, S. Yamda, N. Matsumoto, N. Miyake, and T. Kosho
- Organizer
  American Society of Human Genetics 2017 Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] マウス脳の各発達過程におけるヒアルロン酸代謝関連酵素の発現の定量的解析2017
- Author(s)
  山田修平、三輪一貴、水本秀二
- Organizer
  平成28年度　新学術領域「神経糖鎖生物学」最終シンポジウム
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] CRISPR/Cas9を用いたMusculocontractural Ehlers-Danlos Syndrome-CHST14ノックアウトマウスの作製と病態解析2017
- Author(s)
  〇笠原（仁田原）優子、島津苑子、増田千明、積田奈々、水本秀二、井上(上野) 由紀子、井上高良、吉沢隆浩、高橋有希、池上良、中山淳、武田伸一、渡邉淳、古庄知己、岡田尚巳
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）、第40回日本分子生物学会年会、第90回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] The mammalian chondroitinase, hyaluronidase 4, is produced by human mast cells and generates CS cleavage neo-epitopes2017
- Author(s)
  Brooke L. Farrugia, Shuji Mizumoto, Megan S. Lord, Shuhei Yamada, Bruce Caterson, John M. Whitelock
- Organizer
  7 Lakes Proteoglycan Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] ヒアルロニダーゼ1および４の基質認識に関与するアミノ酸残基の解析2017
- Author(s)
  小林智恵里、白水仁子、稲葉史恵、安部優貴子、水本秀二、山田修平
- Organizer
  第63回日本薬学会東海支部総会・大会
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] 中枢神経系におけるコンドロイチン硫酸/ヒアルロン酸の分解機構に関する研究2017
- Author(s)
  永井冴、藤井貴夢、水本秀二、山田修平
- Organizer
  平成28年度　新学術領域「神経糖鎖生物学」最終シンポジウム
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] Development of diagnostic method of Ehlers-Danlos syndrome using nano-LC/MS/MS2017
- Author(s)
  ◯山田和夫、渡辺淳、古庄知己、水本秀二、山田修平、竹下治男、松本健一
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）、第40回日本分子生物学会年会、第90回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] コンドロイチン硫酸およびヘパリンはヒストンにより誘発された致死性血栓症を軽減する2017
- Author(s)
  ○長野文彦、水野智博、水本秀二、高橋和男、坪井直毅、丸山彰一、山田修平、永松正
- Organizer
  第63 回日本薬学会東海支部総会・大会
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] 発達段階の脳におけるコンドロイチン硫酸/ヒアルロン酸分解酵素の発現解析2017
- Author(s)
  山田修平、三輪一貴、水本秀二
- Organizer
  第49回日本結合組織学会学術大会
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] ルイス肺がん細胞による腫瘍形成におけるRAGE の役割に関する研究2017
- Author(s)
  ○幸村省吾、鈴木麻未、水本秀二、菅原一幸、山田修平
- Organizer
  第63 回日本薬学会東海支部総会・大会
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] 脊髄損傷モデルマウスへのヒアルロニダーゼの投与2017
- Author(s)
  直井友弥、柴本秀太、水本秀二、勝又優子、森岡　幸、武内恒成、山田修平
- Organizer
  第63回日本薬学会東海支部総会・大会
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] コンドロイチン硫酸は細胞外ヒストンによる血管内皮障害を介した臓器障害を抑制する2017
- Author(s)
  ○長野文彦、水野智博、水本秀二、吉岡憲吾、高橋和男、坪井直毅、丸山彰一、山田修平、永松正
- Organizer
  日本医療薬学会第１回フレッシャーズカンファレンス
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] The mammalian chondroitinase, hyaluronidase 4, is produced by human mast cells and generates CS cleavage neo-epitopes2017
- Author(s)
  〇Brooke L. Farrugia, Shuji Mizumoto, Megan S. Lord, Shuhei Yamada, Bruce Caterson, and John M. Whitelock
- Organizer
  7 Lakes Proteoglycans Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] デルマタン硫酸エピメラーゼ欠損によるmusculocontractural Ehlers-Danlos Syndromeの既報告3例と新規3例における臨床像の検討2017
- Author(s)
  〇運﨑愛、Charlotte Kvist Lautrup、Keng Wee Teik、水本秀二、Heng Hock Sin、Irene Kibaek Nielsen、Sara Markholt、山田修平、松本直通、三宅紀子、古庄知己
- Organizer
  日本人類遺伝学会第62回大会
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] コンドロイチン硫酸を特異的に加水分解するヒアルロニダーゼ４の細胞内局在の解析2017
- Author(s)
  牧野冴紀、水本秀二、山田修平
- Organizer
  第36回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] Integrated neuroglycobiology for proteoglycans and chondroitin sulfate-binding proteins2017
- Author(s)
  ◯Shuji Mizumoto, Yusuke Yoshikawa, Shuhei Yamada, Kosei Takeuchi, Yoshiaki Nakayama, Akira Kurosaka, Keiichiro Matsushima, Nobuyuki Miyamoto, Wataru Takada, Hirofumi Kodera, Naomichi Matsumoto, Hirotomo Saitsu, Gunnar Dick, James W. Fawcett, Jessica C. F. Kwok, and Kazuyuki Sugahara
- Organizer
  平成28年度　新学術領域「神経糖鎖生物学」最終シンポジウム
- Place of Presentation
  JPタワー名古屋(名古屋)
- Year and Date
  2017-03-03
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] デルマタン4-O-硫酸基転移酵素-1の欠損によるエーラス・ダンロス症候群患者由来の尿中デルマタン硫酸の定量解析2016
- Author(s)
  ◯水本秀二、古庄知己、籏持淳、本田智子、山田修平、菅原一幸
- Organizer
  日本薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2016
- Place of Presentation
  長良川国際会議場・岐阜都ホテル(岐阜)
- Year and Date
  2016-10-30
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] マウス脳におけるコンドロイチン硫酸とヒアルロン酸の分解活性の検出2016
- Author(s)
  石川輝、水本秀二、山田修平
- Organizer
  第62回日本薬学会東海支部総会大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] コンドロイチン硫酸に特異的な加水分解酵素であるHYAL4の酵母（Pichia pastoris）での発現および精製2016
- Author(s)
  柴本秀太、杉田真千子、水本秀二、菅原一幸、山田修平
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] コンドロイチン硫酸を特異的に加水分解するヒアルロニダーゼ４の細胞内局在の解析2016
- Author(s)
  三輪茜音、水本秀二、山田修平
- Organizer
  第62回日本薬学会東海支部総会大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] Quantification of dermatan sulfate from urine in Ehlers-Danlos syndrome caused by carbohydrate sulfotransferase 14 (CHST14)/dermatan 4-O-sulfotransferase-1 (D4ST1) deficiency2016
- Author(s)
  ◯Shuji Mizumoto, Tomoki Kosho, Atsushi Hatamochi, Tomoko Honda, Shuhei Yamada, and Kazuyuki Sugahara
- Organizer
  XXVIII International Carbohydrate (ICS2016)
- Place of Presentation
  Marriott Hotel (New Orleans, USA)
- Year and Date
  2016-07-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] ヒアルロニダーゼ1および4におけるコンドロイチン硫酸およびヒアルロン酸の認識に関わるアミノ酸残基の解析2016
- Author(s)
  山田修平、安倍優貴子、山極健太郎、水本秀二
- Organizer
  第48回日本結合組織学会学術大会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] デルマタン硫酸の生合成不全によるエーラス・ダンロス症候群の糖鎖生物学的研究2016
- Author(s)
  水本秀二, 古庄知己, 本田智子,中島正宏, Thomas Muller, 三宅紀子, 籏持淳, 松本直通, Andreas R Janecke, 池川志郎, 菅原一幸, ○山田修平
- Organizer
  第35回日本糖質学会年会
- Place of Presentation
  高知市文化プラザ（高知）
- Year and Date
  2016-09-03
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] 多発性骨折と骨粗鬆症はグリコサミノグリカンの生合成に関わる糖転移酵素の変異によって引き起こされる2016
- Author(s)
  ◯水本秀二, Florian Job, Laurie Smith, Natario Couser, Ashley Brazil, Howard Saul, Melanie Patterson, Margaret I. Gibson, Sarah Soden, Neil Miller, Isabelle Thiffault, Carol Saunders, 山田修平, Katrin Hoffman, 菅原一幸, Emily Farrow
- Organizer
  糖鎖科学中部拠点第13回若手の力フォーラム
- Place of Presentation
  岐阜大学(岐阜）
- Year and Date
  2016-11-26
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] エーラス・ダンロス症候群患者由来の尿中デルマタン硫酸の定量2016
- Author(s)
  ◯水本秀二, 古庄知己, 籏持淳, 本田智子, 山田修平, 菅原一幸
- Organizer
  第８０回日本生化学会中部支部例会・シンポジウム
- Place of Presentation
  三重大学講堂（津）
- Year and Date
  2016-05-21
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] グリコサミノグリカンの生合成に関わる糖転移酵素の変異による多発性骨折と骨粗鬆症2016
- Author(s)
  ◯水本秀二, Florian Job, Laurie Smith, Natario Couser, Ashley Brazil, Howard Saul, Melanie Patterson, Margaret I. Gibson, Sarah Soden, Neil Miller, Isabelle Thiffault, Carol Saunders, 山田修平, Katrin Hoffman, 菅原一幸, Emily Farrow
- Organizer
  第８９回日本生化学会大会
- Place of Presentation
  仙台国際センター・東北大学川内北キャンパス (仙台)
- Year and Date
  2016-09-27
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] 脳・神経系におけるコンドロイチン硫酸/ヒアルロン酸分解機構に関する研究2016
- Author(s)
  山田修平、永井冴、三輪一貴、水本秀二
- Organizer
  第48回日本結合組織学会学術大会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] Multiple fractures and severe osteoporosis caused by mutations in a glycosyltransferase responsible for biosynthesis of glycosaminoglycans2016
- Author(s)
  ◯Shuji Mizumoto, Florian Job, Laurie Smith, Natario Couser, Ashley Brazil, Howard Saul, Melanie Patterson, Margaret I. Gibson, Sarah Soden, Neil Miller, Isabelle Thiffault, Carol Saunders, Shuhei Yamada, Katrin Hoffman, Kazuyuki Sugahara, Emily Farrow
- Organizer
  The 10th International Symposium on Glycosyltransferases (GlycoT2016)
- Place of Presentation
  The Hospital for Sick Children (Tronto, Canada)
- Year and Date
  2016-06-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] Studies on the mechanism of degradation of chondroitin sulfate/hyaluronan in central nervous system2016
- Author(s)
  Shuhei Yamada, Sae Nagai, Shuji Mizumoto
- Organizer
  XXVIII International Carbohydrate Symposium
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] Detection of the degradation activities of chondroitin sulfate and hyaluronan in mouse brain as well as cultured cell lines2016
- Author(s)
  ◯Shuji Mizumoto, Tomomasa Yamanaka, Sae Nagai, and Shuhei Yamada
- Organizer
  The 3rd International Symposium on Glyco-Neuroscience
- Place of Presentation
  淡路夢舞台国際会議場（淡路）
- Year and Date
  2016-01-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25860037
[Presentation] デルマタン4-O-硫酸基転移酵素-1欠損に基づくエーラスダンロス症候群モデルマウスの作製および病態解析2016
- Author(s)
  ◯笠原優子、積田奈々、増田千明、島田苑子、水本秀二、井上由起子、井上高良、吉沢隆浩、中山淳、高橋有希、武田伸一、古庄知己、岡田尚巳
- Organizer
  第８９回日本生化学会大会
- Place of Presentation
  仙台国際センター・東北大学川内北キャンパス (仙台)
- Year and Date
  2016-09-26
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] Quantitative analysis of the expression of hyaluronan-chondroitin sulfate-degrading enzymes in the mouse brain during development.2016
- Author(s)
  Kazutaka Miwa, Shuji Mizumoto, Shuhei Yamada
- Organizer
  XXVIII International Carbohydrate Symposium
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] Investigation of the amino acid residues in hyaluronidases-1 and -4 responsible for their substrate recognition2016
- Author(s)
  Yukiko Abe, Kentaro Yamagiwa, Shuji Mizumoto, Shuhei Yamada
- Organizer
  XXVIII International Carbohydrate Symposium
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] 第19回日本糖質学会奨励賞受賞講演：グリコサミノグリカンの生合成異常による骨・皮膚疾患の糖鎖解析と癌転移における役割2016
- Author(s)
  ◯水本秀二
- Organizer
  第35回日本糖質学会年会
- Place of Presentation
  高知市文化プラザ（高知）
- Year and Date
  2016-09-01
- Invited
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] 発生段階の異なるマウス脳におけるヒアルロニダーゼファミリーメンバーの発現解析2015
- Author(s)
  三谷真夕、水本秀二、山田修平
- Organizer
  第34回日本糖質学会年会
- Place of Presentation
  東京
- Year and Date
  2015-08-02
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] 低身長を特徴とする遺伝性骨疾患はグリコサミノグリカンの生合成に関わるグルクロン酸転移酵素-Iの変異によって引き起こされる2015
- Author(s)
  ◯水本秀二、Birgit S. Budde、古川諒、Peter Nurnberg、Ingo Kennerknecht、菅原一幸
- Organizer
  糖鎖科学中部拠点　第１２回若手の力フォーラム
- Place of Presentation
  名城大学（名古屋）
- Year and Date
  2015-11-28
- Data Source
  KAKENHI-PROJECT-25860037
[Presentation] Loss-of-function mutation of glucuronyltransferase-I causes skeletal dysplasia in a consanguineous clan from the island of Nias/Indonesia2015
- Author(s)
  ◯Shuji Mizumoto, Birgit S. Budde, Ryo Kogawa, Christian Becker, Janine Altmuller, Holger Thiele, Franz Ruschendorf, Mohammad R. Toliat, Gerrit Kaleschke, Johannes M. Hammerle, Wolffang Hahne, Kazuyuki Sugahara, Peter Nurnberg, Ingo Kennerknecht
- Organizer
  9th International Conference on Proteoglycans and 10th Pan-Pacific Connective Tissue Societies Symposium
- Place of Presentation
  Ewha Womans University (Seoul, Korea)
- Year and Date
  2015-08-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25860037
[Presentation] グリコサミノグリカンの生合成に関わるグルクロン酸転移酵素-Iの新規変異による骨疾患の糖鎖生物学的研究2015
- Author(s)
  ○水本秀二, Birgit S. Budde, 古川諒, Christian Becker, Janine Altmuller, Holger Thiele, Franz Ruschendorf, Mohammad R. Toliat, Gerrit Kaleschke, Johannes M. Hammerle, Wolffang Hohne, 菅原一幸, Peter Nurnberg, Ingo Kennerknecht
- Organizer
  第34回日本糖質学会年会
- Place of Presentation
  東京大学（東京）
- Year and Date
  2015-07-31
- Data Source
  KAKENHI-PROJECT-25860037
[Presentation] グリコサミノグリカンの生合成に関わるグルクロン酸転移酵素-Iの変異によるインドネシアのニアス島で見つかった骨疾患2015
- Author(s)
  ◯Shuji Mizumoto, Birgit S. Budde, Ryo Kogawa, Christian Becker, Janine Altmuller, Holger Thiele, Franz Ruschendorf, Mohammad R. Toliat, Gerrit Kaleschke, Johannes M. Hammerle, Wolffang Hohne, Kazuyuki Sugahara, Peter Nurnberg, Ingo Kennerknecht
- Organizer
  第３８回日本分子生物学会年会・第８８回日本生化学会大会・合同大会
- Place of Presentation
  神戸ポートアイランド（神戸）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25860037
[Presentation] ヒアルロニダーゼ1および4におけるコンドロイチン硫酸およびヒアルロン酸の認識に関わるアミノ酸残基の解析2015
- Author(s)
  安倍優貴子、山極健太郎、岩月遥奈、水本秀二、山田修平
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] ヒトの癌細胞株や癌組織におけるヒアルロニダーゼ4の発現解析2015
- Author(s)
  西島大樹、水本秀二、山田修平
- Organizer
  第61回日本薬学会東海支部大会
- Place of Presentation
  名古屋
- Year and Date
  2015-07-04
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] Investigation of the Amino Acid Residue Responsible for Diferrent Substrate Specificity of Hyaluronidases-1 and -42015
- Author(s)
  Kentaro Yamagiwa, Haruna Iwatsuki, Yukiko Abe, Shuji Mizumoto, and Shuhei Yamada
- Organizer
  9th International Conference on Proteoglycans and 10th Pan-Pacific Connective Tissue Societies Symposium
- Place of Presentation
  Seoul, Korea
- Year and Date
  2015-08-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] ヒアルロニダーゼ1と4の基質認識の違いに関与するアミノ酸残基の解析2015
- Author(s)
  山極健太郎、岩月遥奈、安倍優貴子、水本秀二、山田修平
- Organizer
  第34回日本糖質学会年会
- Place of Presentation
  東京
- Year and Date
  2015-08-02
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] コンドロイチン・デルマタン・ヘパラン硫酸の生合成に関わるグルクロン酸転移酵素-Iの変異(P140L)による骨疾患の糖鎖生物学的研究2015
- Author(s)
  ○水本秀二, Birgit S. Budde, 古川諒, Christian Becker, Janine Altmuller, Holger Thiele, Franz Ruschendorf, Mohammad R. Toliat, Gerrit Kaleschke, Johannes M. Hammerle, Wolffang Hohne, 菅原一幸, Peter Nurnberg, Ingo Kennerknecht
- Organizer
  第７９回日本生化学会中部支部例会
- Place of Presentation
  信州大学松本キャンパス（松本）
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-25860037
[Presentation] 酵母（Pichia pastoris）を用いたヒアルロニダーゼ４の発現及び精製2015
- Author(s)
  杉田真千子、柴本秀太、水本秀二、菅原一幸、山田修平
- Organizer
  第34回日本糖質学会年会
- Place of Presentation
  東京
- Year and Date
  2015-08-02
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] Quantitative Analysis of the Expression of Hyaluronidases in the Mouse Brain during Development2015
- Author(s)
  Mayu Mitani, Shuji Mizumoto, Shuhei Yamada
- Organizer
  9th International Conference on Proteoglycans and 10th Pan-Pacific Connective Tissue Societies Symposium
- Place of Presentation
  Seoul, Korea
- Year and Date
  2015-08-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] Cellular localization of chondroitin sulfate hydrolase, hyaluronidase－42015
- Author(s)
  Yumiko Nomura, Shuji Mizumoto, and Shuhei Yamada
- Organizer
  9th International Conference on Proteoglycans and 10th Pan-Pacific Connective Tissue Societies Symposium
- Place of Presentation
  Seoul, Korea
- Year and Date
  2015-08-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] Development of novel monoclonal antibodies against chondroitin sulfate, and their application to glycobiology and glycopathology2014
- Author(s)
  Peraphan Pothacharoen, Duriya Fongmoon, Shuji Mizumoto, Kazuyuki Sugahara,、Prachya Kongtawelert
- Organizer
  6th Asian Community of Glycoscience and Glycotechnology (ACGG)
- Place of Presentation
  University of Hyderabad(インド)
- Year and Date
  2014-12-08
- Data Source
  KAKENHI-PROJECT-25670018
[Presentation] Spondyloepimetaphyseal dysplasia and Ehlers-Danlos syndrome caused by mutations of glycosaminoglycan biosynthetic enzymes, GalT-II and DS-epimerase2014
- Author(s)
  Shuji Mizumoto, Masahiro Nakajima, Thomas Muller Noriko Miyake, Ryo Kogawa, Yoshie Komatsu, Naomichi Matsumoto, Andreas R Janecke, Shiro Ikegawa, Kazuyuki Sugahara
- Organizer
  Joint Meeting of the Society for Glycobiology and the Japanese Society of Carbohydrate Research
- Place of Presentation
  Hilton Hotel (Hawaii, USA)
- Year and Date
  2014-11-19
- Data Source
  KAKENHI-PROJECT-25860037
[Presentation] 発生段階の異なるマウス脳におけるヒアルロニダーゼファミリーメンバーの発現解析2014
- Author(s)
  大岩友香、水本秀二、小島良二、永松正、山田修平
- Organizer
  第60回日本薬学会東海支部総会
- Place of Presentation
  鈴鹿医療大学（鈴鹿）
- Year and Date
  2014-07-05
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Mechanism of glycosaminoglycan -mediated tumor metastasis2014
- Author(s)
  Kazuyuki Sugahara, Shuji Mizumoto
- Organizer
  The 27th International Carbohydrate Symposium
- Place of Presentation
  Indian Institute of Science (India)
- Year and Date
  2014-01-15
- Invited
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] プロテオグリカン糖側鎖の生合成異常による遺伝性の骨・皮膚疾患2014
- Author(s)
  水本秀二
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都国際会議場(京都)
- Year and Date
  2014-10-16
- Data Source
  KAKENHI-PROJECT-25860037
[Presentation] コンドロイチン硫酸特異的加水分解酵素ヒアルロニダーゼ-4の細胞内局在の解析2014
- Author(s)
  森本千夏、野村優美子、水本秀二、山田修平
- Organizer
  第60回日本薬学会東海支部総会
- Place of Presentation
  鈴鹿医療大学（鈴鹿）
- Year and Date
  2014-07-05
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] PAPS合成酵素2の変異は常染色体劣性型短脊柱症を引き起こす2014
- Author(s)
  水本秀二, 飯田有俊, Pelin Ozlem Simsek-Kiper, 星野冬馬, Nursel Elcioglu, Eva Horemuzova, Stefan Geiberger, Gozde Yesil, Hulya Kayserili, Gulen Eda Utine, Koray Boduroglu, 渡邉成彦, 大橋博文, Yasemin Alanay, 西村玄, 池川志郎, 菅原一幸
- Organizer
  第33回日本糖質学会年会
- Place of Presentation
  名古屋大学（名古屋）
- Year and Date
  2014-08-11
- Data Source
  KAKENHI-PROJECT-25860037
[Presentation] Integrated neuroglycobiology for proteoglycans and chondroitin sulfate-binding proteins2014
- Author(s)
  Kazuyuki Sugahara, Shuji Mizumoto, Yusuke Yoshikawa, Shuhei Yamada, Kosei Takeuchi, Yoshiaki Nakayama, Akira Kurosaka, Keiichiro Matsushima, Nobuyuki Miyamoto, Wataru Takada, Hirofumi Kodera, Naomichi Matsumoto, Hirotomo Saitsu, Gunnar Dick, James W. Fawcett, Jessica C. F. Kwok
- Organizer
  International Symposium on Glyco-Neuroscience
- Place of Presentation
  Awaji
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Effects of Sesamin on the Biosynthesis of Chondroitin Sulfate Proteoglycans in Human Articular Chondrocytes in Primary Culture2014
- Author(s)
  Peraphan Pothacharoen, Sumet Najarus, Jongkolnee Settakorn, Shuji Mizumoto, Kazuyuki Sugahara, Prachya Kongtawelert
- Organizer
  Joint Meeting of the Society for Glycobiology and the Japanese Society of Carbohydrate Research
- Place of Presentation
  Hawai Hotel Hilton(米国)
- Year and Date
  2014-11-20
- Data Source
  KAKENHI-PROJECT-25670018
[Presentation] コンドロイチン硫酸代謝におけるヒアルロニダーゼの役割2014
- Author(s)
  山田修平、本田智子、金岩知之、水本秀二、菅原一幸
- Organizer
  第46回日本結合組織学会学術大会第61回マトリックス研究会大会合同学術集会
- Place of Presentation
  ウインク愛知（名古屋）
- Year and Date
  2014-06-06
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] グリコサミノグリカンの生合成異常による遺伝性の骨・皮膚疾患2014
- Author(s)
  水本秀二
- Organizer
  第22回PGフォーラム(第４６回日本結合組織学会学術大会・第６１回マトリックス研究会大会・合同学術大会)
- Place of Presentation
  ウインク愛知(名古屋)
- Year and Date
  2014-06-07
- Invited
- Data Source
  KAKENHI-PROJECT-25860037
[Presentation] ヒトヒアルロニダーゼの基質認識に必要なアミノ酸残基の解析2014
- Author(s)
  岩月遥奈、水本秀二、金岩知之、菅原一幸、山田修平
- Organizer
  第60回日本薬学会東海支部総会
- Place of Presentation
  鈴鹿医療大学（鈴鹿）
- Year and Date
  2014-07-05
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Effects of Sesamin on the Biosynthesis of Chondroitin Sulfate Proteoglycans in Human Articular Chondrocytes in Primary Culture2014
- Author(s)
  Peraphan Pothacharoen, Sumet Najarus, Jongkolnee Settakorn, Shuji Mizumoto, Kazuyuki Sugahara, Prachya Kongtawelert
- Organizer
  Gordon Conference on Proteoglycans
- Place of Presentation
  Proctor Academy(米国)
- Year and Date
  2014-07-07
- Data Source
  KAKENHI-PROJECT-25670018
[Presentation] Expression Analysis of Hyaluronidases in the Mouse Brain during Development2014
- Author(s)
  Yuka Oiwa, Shuji Mizumoto, Ryoji Kojima, Tadashi Nagamatsu, Shuhei Yamada
- Organizer
  oint Meeting of the Society for Glycobiology and the Japanese Society of Carbohydrate Research “Integrating Glycoscience from Biology and Chemistry to Medicine”
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2014-11-18
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Mass preparation of oligosaccharides with intestinal absorption capacity by hydrolysis of chondroitin sulfate polysaccharides with subcritical water microreaction system2013
- Author(s)
  Kazuyuki Sugahara, Shuhei Yamada, Shuji Mizumoto, Keiichiro Matsushima, Haruo Ura, and Nobuyuki Miyamoto
- Organizer
  The 13th International Conference on Functional and Medical Foods with Bioactive Compounds : Science and Practical Applications/The First International Symposium of Academic Society for Functional Foods and Bioactive Compounds
- Place of Presentation
  The Kyoto Prefectural University (Kyoto)
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Mass Preparation of Oligosaccharides with Intestinal Absorption Capacity by Hydrolysis of Chondroitin Sulfate Polysaccharides with Subcritical Water Microreaction System2013
- Author(s)
  Kazuyuki Sugahara, Shuhei Yamada, Shuji Mizumoto, Keiichiro Matsushima, Haruo Ura, and Nobuyuki Miyamoto
- Organizer
  13th International Conference of FFC and 1st International Symposium of Academic Society for Functional Foods and Bioactive Compounds
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] マイクロ化学プロセスによる新規糖鎖食品の開発2013
- Author(s)
  松嶋景一郎、浦晴雄、宮本宣之、菅原一幸、山田修平、水本秀二
- Organizer
  北海道立総合研究機構　技術移転フォーラム2013
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Novel highly sulfated hexasaccharide sequences isolated from chondroitin sulfate of shark fin cartilage: Insights into the sugar sequences involved in brain development2013
- Author(s)
  Kazuyuki Sugahara, Shuji Mizumoto, Kittiwan Kalayanamitra, Shuhei Yamada, and Prachya Kongtawelert
- Organizer
  8th International Conference on Proteoglycans
- Place of Presentation
  Frankfurt, Germany
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Development of novel monoclonal antibodies against chondroitin sulfate, and their application to glycobiology and glycopathology2013
- Author(s)
  Peraphan Pothacharoen, Duriya Fongmoon, Shuji Mizumoto, Kazuyuki Sugahara,Prachya Kongtawlert
- Organizer
  The 5th annual conference for Asian Communications of Glycobiology and Glycotechnology
- Place of Presentation
  Khon Kaen University (タイ国)
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Receptor for Advanced Glycation End-products (RAGE) Functions as Receptor for Sulfated Glycosaminoglycans (GAGs) : Anti-RAGE Antibody or Sulfated GAGs Inhibit Lung Metastasis of Tumor Cells2013
- Author(s)
  Kazuyuki Sugahara, Jun Takahashi, Shuji Mizumoto
- Organizer
  22nd International Symposium on Glycoconjugates
- Place of Presentation
  Dalian Institute of Chemical Phisics, Chinese Academy of Sciences (China)
- Year and Date
  2013-06-28
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Development of novel monoclonal antibodies against chondroitin sulfate, and their application to glycobiology and glycopathology2013
- Author(s)
  Peraphan Pothacharoen, Duriya Fongmoon, Shuji Mizumoto, Kazuyuki Sugahara, Prachya Kongtawlert
- Organizer
  The 5th annual conference for Asian Communications of Glycobiology and Glycotechnology
- Place of Presentation
  Khon Kaen University (Thailand.)
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] ヒトとマウスにおけるコンドロイチン硫酸加水分解酵素の基質特異性の違いに関わるアミノ酸残基の同定2013
- Author(s)
  山田修平、金岩知之、宮崎杏、古川諒、水本秀二、菅原一幸
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Development of novel monoclonal antibodies against chondroitin sulfate, and their application to glycobiology and glycopathology2013
- Author(s)
  Peraphan Pothacharoen, Duriya Fongmoon, Shuji Mizumoto, Kazuyuki Sugahara,Prachya Kongtawlert
- Organizer
  The 5th annual conference for Asian Communications of Glycobiology and Glycotechnology
- Place of Presentation
  Khon Kaen University(タイ国)
- Data Source
  KAKENHI-PROJECT-25670018
[Presentation] ヒアルロニダーゼはコンドロイチン4-硫酸に対しヒアルロン酸と同程度の強い加水分解活性をもつ2013
- Author(s)
  山田修平、本田智子、金岩知之、水本秀二、菅原一幸
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] RAGEは癌細胞の肺転移に関わるコンドロイチン硫酸の受容体として機能する2012
- Author(s)
  水本秀二,高橋潤, 菅原一幸
- Organizer
  第31回日本糖質学会年会
- Place of Presentation
  鹿児島市民文化ホール、(口頭発表)and Kazuyuki Sugahara、
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] コンドロイチン硫酸特異的加水分解酵素ヒアルロニダーゼ-4の酵素活性に必要なアミノ酸残基の同定2012
- Author(s)
  山田修平、金岩知之、宮崎杏、水本秀二、菅原一幸
- Organizer
  第５８回日本薬学会東海支部総会・大会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Receptor for Advanced Glycation End-products (RAGE) functions as areceptor for glycosaminoglycans involved in pulmonary metastasis2012
- Author(s)
  Shuji MIZUMOTO, Jun TAKAHASHI,Kazuyuki SUGAHARA
- Organizer
  The 10th International Symposium for Future Drug Discovery and Medical Care
- Place of Presentation
  Hokkaido Univ.、(Poster& Short talk)
- Year and Date
  2012-10-03
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] コンドロイチン硫酸特異的加水分解酵素ヒアルロニダーゼ-4の酵素活性に必要なアミノ酸残基の同定2012
- Author(s)
  金岩知之、宮崎杏、水本秀二、菅原一幸、山田修平
- Organizer
  第49回日本生化学会北海道支部例会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] ヒアルロニダーゼの本来の基質はヒアルロン酸ではなくコンドロイチン硫酸2012
- Author(s)
  山田修平、本田智子、金岩知之、水本秀二、菅原一幸
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Receptor for Advanced Glycation End Products (RAGE)は癌細胞の肺転移に関わるコンドロイチン硫酸の受容体として機能する2012
- Author(s)
  水本秀二, 高橋潤, 菅原一幸
- Organizer
  日本薬学会北海道支部第138回例会
- Place of Presentation
  札幌コンベンションセンター(札幌市)
- Year and Date
  2012-06-16
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] コンドロイチン硫酸に特異的な加水分解酵素に関する研究2012
- Author(s)
  山田修平，金岩知之，宮崎杏，古川諒，水本秀二，菅原一幸
- Organizer
  第31回日本糖質学会年会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Receptor for Advanced Glycation End products (RAGE)は肺転移に関わるがん細胞表面のグリコサミノグリカン受容体として機能する2012
- Author(s)
  ○高橋潤, 水本秀二 , 菅原一幸
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場(福岡)
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] がん細胞の肺転移に関わる硫酸化グリコサミノグリカンの受容体の同定2012
- Author(s)
  高橋潤, 水本秀二, 菅原一幸
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] ヒトヒアルロニダーゼはコンドロイチン硫酸Aをヒアルロン酸と同程度の速度で加水分解する2012
- Author(s)
  本田智子、金岩知之、水本秀二、菅原一幸、山田修平
- Organizer
  第49回日本生化学会北海道支部例会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Novel highly sulfated hexasaccharide sequences isolated from chondroitin sulfate of shark fin cartilage: Insights into the sugar sequences involved in brain development2012
- Author(s)
  Shuji Mizumoto, Saori Murakoshi,Kittiwan Kalayanamitra, Sarama Sathyaseelan Deepa, Shigeyuki Fukui, Prachya Kongtawelert, Shuhei Yamada, and Kazuyuki Sugahara
- Organizer
  2012年度包括型脳科学研究推進支援ネットワーク・夏のワークショップ
- Place of Presentation
  仙台国際センター、(ポスター発表)
- Year and Date
  2012-07-26
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] グルクロン酸転移酵素-I の変異によって引き起こされる新規ラーセン様症候群2012
- Author(s)
  水本秀二, Sevjidmaa Baasanjav, Lihadh Al-Gazali, 橋口太志, Bjoern Fischer, Denise Horn, Dominik Seelow, Bassam R. Ali, Samir A.A. Aziz, Ruth Langer, Ahmed A.H. Saleh, Christian Becker, Gudrun Nürnberg, Vincent Cantagrel, Joseph G. Gleeson, Delphine Gomez, Jean-Baptiste Michel, Sigmar Stricker, Tom H. Lindner, Peter Nürnberg, Stefan Mundlos, Katrin Hoffmann, 菅原一幸
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] グルクロン酸転移酵素-Iの変異によって引き起こされる新規ラーセン様症候群2012
- Author(s)
  ◯水本秀二, Baasanjav S, Al-Gazali L, 橋口太志, Mundlos S, Hoffmann K, 菅原一幸 et al.
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学(札幌市)
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] グルクロン酸転移酵素-Iの変異によって引き起こされる新規ラーセン様症候群2012
- Author(s)
  水本秀二, Sevjidmaa Baasanjav, Lihadh Al-Gazali, 橋口太志, Bjoern Fischer, Denise Horn, Dominik Seelow, Bassam R.Ali, Samir A.A.Aziz, Ruth Langer, Ahmed A.H.Saleh, Christian Becker, Gudrun Nurnberg, Vincent Cantagrel, Joseph G.Gleeson, Delphine Gomez, Jean-Baptiste Michel, Sigmar Stricker, Tom H.Lindner, Peter Nurnberg, Stefan Mundlos, Katrin Hoffmann, 菅原一幸
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] グルクロン酸転移酵素-Iの変異によって引き起こされる新規ラーセン様症候群2012
- Author(s)
  水本秀二,Sevjidmaa Baasanjav,LihadhAl-Gazali,橋口太志,他19名
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学、(口頭発表)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] がんの肺転移に関わるグリコサミノグリカン受容体(RAGE)の同定2012
- Author(s)
  高橋潤, 水本秀二, 菅原一幸
- Organizer
  第49回日本生化学会北海道支部例会
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2012-07-20
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] ○高橋潤, 水本秀二 , 菅原一幸2012
- Author(s)
  ○高橋潤, 水本秀二 , 菅原一幸
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学(札幌市)
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] Receptor for Advanced Glycation End-products (RAGE) functions as a receptor for glycosaminoglycans involved in pulmonary metastasis2012
- Author(s)
  Shuji Mizumoto, Jun Takahashi, Kazuyuki Sugahara
- Organizer
  The 10th International Symposium for Future Drug Discovery and Medical Care
- Place of Presentation
  Hokkaido Univ. (Sapporo)
- Year and Date
  2012-10-03
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] サメヒレ軟骨コンドロイチン硫酸由来の新規な六糖配列の単離2012
- Author(s)
  水本秀二,村越早織,Kittiwan Kalayanamitra, Sarama Sathyaseelan Deepa, 福井成行, Prachya Kongtawelert, 山田修平, 菅原一幸
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場およびマリンメッセ福岡、(ポスター発表)
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] Receptor for Advanced Glycation End Products (RAGE)は癌細胞の肺転移に関わるコンドロイチン硫酸の受容体として機能する2012
- Author(s)
  水本秀二,高橋潤,菅原一幸
- Organizer
  日本薬学会北海道支部第138回例会
- Place of Presentation
  札幌コンベンションセンター、(口頭発表)
- Year and Date
  2012-06-16
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] ヒトヒアルロニダーゼのコンドロイチン４硫酸に対する高い加水分解活性2012
- Author(s)
  本田智子、金岩知之、水本秀二、菅原一幸、山田修平
- Organizer
  第31回日本糖質学会年会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] RAGEは癌細胞の肺転移に関わるコンドロイチン硫酸の受容体として機能する2012
- Author(s)
  水本秀二, 高橋潤, 菅原一幸
- Organizer
  第31回日本糖質学会年会
- Place of Presentation
  鹿児島市民ホール(鹿児島市)
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Receptor for Advanced Glycation End products (RAGE)は肺転移に関わるがん細胞表面のグリコサミノグリカン受容体として機能する2012
- Author(s)
  高橋潤, 水本秀二, 菅原一幸
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場(福岡市)
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] ルイス肺癌細胞表面上のコンドロイチン硫酸E構造の発現低下による転移抑制2011
- Author(s)
  水本秀二、渡邊基夫、山田修平、菅原一幸
- Organizer
  日本薬学会北海道支部第136回例会
- Place of Presentation
  札幌コンベンションセンター(札幌市)
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] コンドロイチン硫酸E構造の発現調節によるルイス肺癌細胞の転移抑制2011
- Author(s)
  水本秀二、渡邊基夫、山田修平、菅原一幸
- Organizer
  日本薬学会北海道支部第136例会
- Place of Presentation
  札幌コンベンションセンター、(口頭発表)
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] A deficiency of glycosaminoglycans causes cardiac and joint disorders2011
- Author(s)
  Sevjidmaa Baasanjav, Lihadh Al-Gazali, Taishi Hashiguchi, Shuji Mizumoto, Bjoern Fischer, Denise Horn, Dominik Seelow, Bassam R.Ali, Samir A.A.Aziz, Ruth Langer, Ahmed A.H.Saleh, Christian Becker, Gudrun Nurnberg, Vincent Cantagrel, Joseph G.Gleeson, Delphine Gomez, Jean-Baptiste Michel, Sigmar Stricker, Tom H.Lindner, Peter Nurnberg, Kazuyuki Sugahara, Stefan Mundlos, Katrin Hoffmann
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都府)
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Loss-of-function mutation of glucuronyltransferase-I causes Larsen-like syndrome2011
- Author(s)
  S.Baasanjav, L.Al-Gazali, T.Hashiguchi, 〇S.Mizumoto, B.Fischer, D.Horn, D.Seelow, B.R.Ali, S.A.A.Aziz, R.Langer, A.A.H.Saleh, C.Becker, G.Nurnberg, V.Cantagrel, J.G.Gleeson, D.Gomez, J.-B.Michel, S.Stricker, T.H.Lindner, P.Nurnberg, K.Sugahara, S.Mundlos, K.Hoffmann
- Organizer
  7th International Conference on Proteoglycans
- Place of Presentation
  QSTATION (Australia)
- Year and Date
  2011-10-18
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Loss-of-function mutation of glucuronyltransferase-I causes Larsen-like syndrome2011
- Author(s)
  S. Baasanjav, L. Al-Gazali, T. Hashiguchi, S. Mizumoto, 他19名
- Organizer
  7th International Conference on Proteoglycans
- Place of Presentation
  Q Station(Australia)、(Poster presentation)
- Year and Date
  2011-10-18
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] Involvement of HNK-1 Sulfotransferase in the Biosynthesis of Chondroitin Sulfate and the GlcUA(3-O-sulfate)-Gal-Gal-Xyl Tetrasaccharide Found in a-Thrombomodulin from Human Urine2011
- Author(s)
  T. Hashiguchi, S. Mizumoto, Y. Nishimura, J. Tamura, ○S. Yamada, K. Sugahara
- Organizer
  7th International Conference on Proteoglycans
- Place of Presentation
  Q STATION (Australia)
- Year and Date
  2011-10-18
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Loss-of-function mutations of dermatan 4-O-sulfotransferase-1 cause a new type of Ehlers-Danlos syndrome2011
- Author(s)
  Shuji Mizumoto, Noriko Miyake, Tomoki Kosho, Shuhei Yamada, Kazuyuki Sugahara, and Naomichi Matsumoto
- Organizer
  The 9th International Symposium for Future Drug Discovery and Medical Care
- Place of Presentation
  Hokkaido Univ、(Poster)
- Year and Date
  2011-09-30
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] Analysis of the expression pattern of dermatan sulfate epimerase-2, which is involved in the bipolar disorder, in the mouse brain during postnatal development2011
- Author(s)
  Chizuru Akatsu, Shuji Mizumoto, Tomoyuki Kaneiwa, Marco Maccarana, Anders Malmström, Shuhei Yamada, ○Kazuyuki Sugahara
- Organizer
  The 9th International Symposium for Future Drug Discovery and Medical Care
- Place of Presentation
  Hokkaido Univ. (Sapporo)
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Involvement of HNK-1 Sulfotransferase in the Biosynthesis of Chondroitin Sulfate and the GlcUA(3-0-sulfate)-Gal-Gal-Xyl Tetrasaccharide Found in a-Thrombomodulin from Human Urine2011
- Author(s)
  T.Hashiguchi, S.Mizumoto, Y.Nishimura, J.Tamura, 〇S.Yamada, K.Sugahara
- Organizer
  7th International Conference on Proteoglycans
- Place of Presentation
  QSTATION (Australia)
- Year and Date
  2011-10-18
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Characterization of a receptor for glycosaminoglycans that mediate experimental lung metastasis2011
- Author(s)
  K.Sugahara, S.Mizumoto, J.Takahashi
- Organizer
  7th International Conference on Proteoglycans
- Place of Presentation
  QSTATION (Australia)(招待講演)
- Year and Date
  2011-10-18
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] A deficiency of glycosaminoglycans causes cardiac and joint disorders2011
- Author(s)
  Sevjidmaa Baasanjav, Lihadh Al-Gazali, Taishi Hashiguchi, ○ Shuji Mizumoto, Bjoern Fischer, Denise Horn, Dominik Seelow, Bassam R. Ali, Samir A.A. Aziz, Ruth Langer, Ahmed A.H. Saleh, Christian Becker, Gudrun Nürnberg, Vincent Cantagrel, Joseph G. Gleeson, Delphine Gomez, Jean-Baptiste Michel, Sigmar Stricker, Tom H. Lindner, Peter Nürnberg, Kazuyuki Sugahara, Stefan Mundlos, Katrin Hoffmann
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都市)
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Loss-of-function mutation of glucuronyltransferase-I causes Larsen-like syndrome2011
- Author(s)
  Baasanjav S, Al-Gazali L, Hashiguchi T, ○Mizumoto S, Sugahara K, Mundlos S, Hoffmann K. et al.
- Organizer
  7th International Conference on Proteoglycans
- Place of Presentation
  Q Station (Australia)
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] コンドロイチン硫酸/デルマタン硫酸の生合成に関わる酵素の欠損による骨・皮膚疾患2011
- Author(s)
  水本秀二,三宅紀子,古庄知己, Mirjam H.H. van Roij, Beyhan Tuysuz,Stefan Mundlos, Stephen P. Robertson, 山田修平, 松本直通, 菅原一幸
- Organizer
  第30回日本糖質学会年会
- Place of Presentation
  長岡リリックホール、(口頭発表)
- Year and Date
  2011-07-11
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] コンドロイチン硫酸/デルマタン硫酸の生合成に関わる酵素の欠損による骨・皮膚疾患2011
- Author(s)
  ○水本秀二, 三宅紀子, 古庄知己, Mirjam H.H. van Roij, Beyhan Tuysuz, Stefan Mundlos, Stephen P. Robertson, 山田修平, 松本直通, 菅原一幸
- Organizer
  第30回日本糖質学会年会
- Place of Presentation
  長岡リリックホール(新潟県)
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] A deficiency of glycosaminoglycans causes cardiac and joint disorders2011
- Author(s)
  Baasanjav S, Al-Gazali L, Hashiguchi T, ○Mizumoto S, Sugahara K, Mundlos S, Hoffmann K. et al.
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都府)
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] Loss-of-function mutations of dermatan 4-O-sulfotransferase-1 cause a new type of Ehlers-Danlos syndrome2011
- Author(s)
  ◯Shuji Mizumoto, Noriko Miyake, Tomoki Kosho, Shuhei Yamada, Kazuyuki Sugahara, and Naomichi Matsumoto
- Organizer
  The 9th International Symposium for Future Drug Discovery and Medical Care
- Place of Presentation
  Hokkaido Univ. (Sapporo)
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] ルイス肺癌細胞表面上のコンドロイチン硫酸E構造の発現低下による転移抑制2011
- Author(s)
  渡邊基夫、水本秀二、山田修平、菅原一幸
- Organizer
  第30回日本糖質学会年会
- Place of Presentation
  長岡リリックホール(新潟県)
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Loss-of-function mutation of glucuronyltransferase-I causes Larsen-like syndrome2011
- Author(s)
  S. Baasanjav, L. Al-Gazali, T. Hashiguchi, ○S. Mizumoto, B. Fischer, D. Horn, D. Seelow, B. R. Ali, S.A.A. Aziz, R. Langer, A. A.H. Saleh, C. Becker, G. Nürnberg, V. Cantagrel, J. G. Gleeson, D. Gomez, J.-B. Michel, S. Stricker, T. H. Lindner, P. Nürnberg, K. Sugahara, S. Mundlos, K. Hoffmann
- Organizer
  7th International Conference on Proteoglycans
- Place of Presentation
  Q STATION (Australia)
- Year and Date
  2011-10-18
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] ルイス肺癌細胞表面上のコンドロイチン硫酸E 構造の発現低下による転移抑制2011
- Author(s)
  水本秀二, 渡邊基夫, 山田修平, 菅原一幸
- Organizer
  日本薬学会北海道支部第136回例会
- Place of Presentation
  札幌コンベンションセンター(札幌市)
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] ルイス肺癌細胞表面上のコンドロイチン硫酸E 構造の発現低下による転移抑制2011
- Author(s)
  渡邊基夫, 水本秀二, 山田修平, ○菅原一幸
- Organizer
  第30回日本糖質学会年会
- Place of Presentation
  長岡リリックホール(長岡市)
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] A deficiency of glycosaminoglycans causes cardiac and joint disorders2011
- Author(s)
  Sevjidmaa Baasanjav, Lihadh Al-Gazali, Taishi Hashiguchi, Shuji Mizumoto , 他19名
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館、(口頭&ポスター発表)
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] デルマタン4-O-硫酸基転移酵素-1の変異は新しいタイプのエーラス・ダンロス症候群を引き起こす2010
- Author(s)
  水本秀二
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-20390019
[Presentation] The E-type structure of chondroitin sulfate on tumor cell surfaces is involved in lung and liver metastases.2010
- Author(s)
  Kazuyuki Sugahara, Fuchuan Li, Sengottuvelan Murugan, Basappa, Taishi Hashiguchi, Shuji Mizumoto, Shuhei Yamada, Kayoko Oguri, Minoru Okayama, Kazuki N.Sugahara, Chun Man Lee, Masayuki Miyasaka, Gerdy B.ten Dam, Toin H.van Kuppevelt
- Organizer
  Asian Communications of Glycobiology and Glycotechnology (ACGG)
- Place of Presentation
  Taipei
- Year and Date
  2010-10-27
- Data Source
  KAKENHI-PROJECT-20390019
[Presentation] コンドロイチン4-0-硫酸基転移酵素-1の欠損によるコンドロイチン硫酸-コアタンパク質結合領域の硫酸化修飾構造に及ぼす影響2010
- Author(s)
  水本秀二
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-20390019
[Presentation] Spondyloepiphyseal dysplasia is caused by multiple mutations in the chondroitin 6-O-sulfotransferase-1 gene2010
- Author(s)
  Shuji Mizumoto
- Organizer
  The 25^<th> International Carbohydrate Symposium (ICS2010)
- Place of Presentation
  Chiba
- Year and Date
  2010-08-03
- Data Source
  KAKENHI-PROJECT-20390019
[Presentation] サメヒレコンドロイチン硫酸由来のコンドロイチナーゼACIに抵抗性を示す新規な六糖の単離と構造解析2009
- Author(s)
  水本秀二
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-20390019
[Presentation] Cell surface chondroitin sulfate E type structure of mouse tumor cell lines is involved in the experimental metastasis to the lung and liver.2009
- Author(s)
  Kazuyuki Sugahara, Shuhei Yamada, Sengottuvelan Murugan, Fuchuan Li, Basappa, Taishi Hashiguchi, Shuji Mizumoto, Kayoko Oguri, Minoru Okayama, Kazuki N. Sugahara, Chun Man Lee, Masayuki Miyasaka, Gerdy B.ten Dam, Toin H.van Kuppevelt
- Organizer
  6th international Conference on Proteoglycan
- Place of Presentation
  Aix-les-Bains, France
- Data Source
  KAKENHI-PROJECT-20390019
[Presentation] Novel CS-E-Binding Proteins in Mouse Brain That May Be Involved in the Neurite Outgrowth Promoting Mechanism through Chondroitin Sulfate E-Type
- Author(s)
  Kazuyuki Sugahara, Shuji Mizumoto, Yusuke Yoshikawa, Shuhei Yamada, and Kosei Takeuchi
- Organizer
  Gordon Research Conference on Proteoglycans 2014
- Place of Presentation
  Andover, USA
- Year and Date
  2014-07-07 – 2014-07-10
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Mass preparation of oligosaccharides with intestinal absorption capacity by hydrolysis of chondroitin sulfate polysaccharides with subcritical water microreaction system
- Author(s)
  Kazuyuki Sugahara, Shuhei Yamada, Shuji Mizumoto, Keiichiro Matsushima, Haruo Ura, and Nobuyuki Miyamoto
- Organizer
  The 13th International Conference on Functional and Medical Foods with Bioactive Compounds: Science and Practical Applications”
- Place of Presentation
  The Kyoto Prefectural University of Medicine (京都)
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Novel highly sulfated hexasaccharide sequences isolated from chondroitin sulfate of shark fin cartilage: Insights into the sugar sequences involved in brain development
- Author(s)
  ○Shuji Mizumoto, Saori Murakoshi, Kittiwan Kalayanamitra, Sarama Sathyaseelan Deepa, Shigeyuki Fuku5, Prachya Kongtawelert, Shuhei Yamada, and Kazuyuki Sugahara
- Organizer
  2012年度　包括型脳科学研究推進支援ネットワーク・夏のワークショップ
- Place of Presentation
  仙台国際センター(仙台)
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] グリコサミノグリカンの生合成に関わる酵素の新規変異による脊椎骨端骨幹端異形成症とエーラス・ダンロス症候群の糖鎖生物学的研究
- Author(s)
  ○水本秀二, 中島正宏, Thomas Muller, 三宅紀子, Indrajit Suresh, 古川諒, 小松由枝, 松本直通, Andreas R Janecke, 池川志郎, 菅原一幸
- Organizer
  第32回日本糖質学会年会
- Place of Presentation
  大阪国際交流センター（大阪）
- Data Source
  KAKENHI-PROJECT-25860037
[Presentation] コンドロイチン硫酸/デルマタン硫酸の生合成に関わる酵素の変異による骨・皮膚疾患の糖鎖生物学的研究
- Author(s)
  ○水本秀二, 中島正宏, Thomas Muller, 三宅紀子, Indrajit Suresh, 古川諒, 小松由枝, 松本直通, Andreas R Janecke, 池川志郎, 菅原一幸
- Organizer
  日本生化学会北海道支部支部例会第50回記念大会
- Place of Presentation
  北海道大学医学部(札幌)
- Data Source
  KAKENHI-PROJECT-25860037
[Presentation] PAPS合成酵素2の変異によって引き起こされる常染色体劣性型短脊柱症
- Author(s)
  ○水本秀二, 飯田有俊, Pelin Ozlem Simsek-Kiper, 星野冬馬, Nursel Elcioglu, Eva Horemuzova, Stefan Geiberger, Gozde Yesil, Hulya Kayserili, Gulen Eda Utine, Koray Boduroglu, 渡邉成彦, 大橋博文, Yasemin Alanay, 西村玄, 池川志郎, 菅原一幸
- Organizer
  日本薬学会第134回年会
- Place of Presentation
  熊本大学工学部(熊本)
- Data Source
  KAKENHI-PROJECT-25860037
[Presentation] Receptor for Advanced Glycation End Products (RAGE)は癌細胞の肺転移に関わるコンドロイチン硫酸の受容体として機能する
- Author(s)
  ○水本秀二, 高橋潤, 菅原一幸
- Organizer
  日本薬学会北海道支部第138回例会
- Place of Presentation
  札幌コンベンションセンター(札幌)
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] Receptor for Advanced Glycation End-products (RAGE) functions as a receptor for glycosaminoglycans involved in pulmonary metastasis
- Author(s)
  ◯Shuji MIZUMOTO, Jun TAKAHASHI, Kazuyuki SUGAHARA
- Organizer
  The 10th International Symposium for Future Drug Discovery and Medical Care
- Place of Presentation
  Hokaido Univ. (Sapporo)
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Receptor for Advanced Glycation End-products (RAGE) functions as a receptor for glycosaminoglycans involved in pulmonary metastasis
- Author(s)
  ◯Shuji MIZUMOTO, Jun TAKAHASHI, Kazuyuki SUGAHARA
- Organizer
  The 10th International Symposium for Future Drug Discovery and Medical Care
- Place of Presentation
  Hokkaido Univ.(Sapporo)
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] Receptor for Advanced Glycation End Products (RAGE)は癌細胞の肺転移に関わるコンドロイチン硫酸の受容体として機能する
- Author(s)
  ○水本秀二、高橋潤、菅原一幸
- Organizer
  日本薬学会北海道支部第138回例会
- Place of Presentation
  札幌コンベンションセンター(札幌市)
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] RAGEは癌細胞の肺転移に関わるコンドロイチン硫酸の受容体として機能する
- Author(s)
  ○水本秀二, 高橋潤, 菅原一幸
- Organizer
  第31回日本糖質学会年会
- Place of Presentation
  鹿児島市民文化ホール(鹿児島)
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] Receptor for Advanced Glycation End-products (RAGE) Functions as Receptor for Sulfated Glycosaminoglycans (GAGs): Anti-RAGE Antibody or Sulfated GAGs Inhibit Lung Metastasis of Tumor Cells
- Author(s)
  Kazuyuki SUGAHARA, Jun TAKAHASHI, Shuji MIZUMOTO
- Organizer
  22nd International Symposium on Glycoconjugates
- Place of Presentation
  Dalian Institute of Chemical Phisics, Chinese Academy of Sciences(中国)
- Data Source
  KAKENHI-PROJECT-25670018
[Presentation] がんの肺転移に関わるグリコサミノグリカン受容体(RAGE)の同定
- Author(s)
  ○高橋潤、水本秀二、菅原一幸
- Organizer
  第49 回日本生化学会北海道支部例会
- Place of Presentation
  北海道大学(札幌市）
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] サメヒレ軟骨コンドロイチン硫酸由来の新規な六糖配列の単離
- Author(s)
  ◯水本秀二, 村越早織, Kittiwan Kalayanamitra, Sarama Sathyaseelan Deepa, 福井成行, Prachya Kongtawelert, 山田修平, 菅原一幸
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場(福岡)
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] Mechanism of glycosaminoglycan-mediated tumor metastasis
- Author(s)
  Kazuyuki Sugahara and Shuji Mizumoto
- Organizer
  The 27th International Carbohydrate Symposium
- Place of Presentation
  Indial Institute of Science (インド)
- Invited
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Receptor for Advanced Glycation End-products (RAGE) Functions as Receptor for Sulfated Glycosaminoglycans (GAGs): Anti-RAGE Antibody or Sulfated GAGs Inhibit Lung Metastasis of Tumor Cells
- Author(s)
  Kazuyuki SUGAHARA, Jun TAKAHASHI, Shuji MIZUMOTO
- Organizer
  22nd International Symposium on Glycoconjugates
- Place of Presentation
  Dalian Institute of Chemical Phisics, Chinese Academy of Sciences(中国)
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Expression Analysis of Hyaluronidases in the Mouse Brain during Development
- Author(s)
  Yuka Oiwa, Shuji Mizumoto, Ryoji Kojima, Tadashi Nagamatsu, Shuhei Yamada
- Organizer
  Joint Meeting of the Society for Glycobiology and the Japanese Society of Carbohydrate Research “Glycans in Neuroscience”
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2014-11-16 – 2014-11-18
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Mass preparation of oligosaccharides with intestinal absorption capacity by hydrolysis of chondroitin sulfate polysaccharides with subcritical water microreaction system
- Author(s)
  Kazuyuki Sugahara, Shuhei Yamada, Shuji Mizumoto, Keiichiro Matsushima, Haruo Ura, Nobuyuki Miyamoto
- Organizer
  he 13th International Conference on Functional and Medical Foods with Bioactive Compounds
- Place of Presentation
  The Kyoto Prefectural University of Medicine(京都)
- Data Source
  KAKENHI-PROJECT-25670018
[Presentation] Mechanism of glycosaminoglycan-mediated tumor metastasis
- Author(s)
  Kazuyuki Sugahara and Shuji Mizumoto
- Organizer
  The 27th International Carbohydrate Symposium
- Place of Presentation
  Indial Institute of Science(インド)
- Invited
- Data Source
  KAKENHI-PROJECT-25670018
[Presentation] RAGEは癌細胞の肺転移に関わるコンドロイチン硫酸の受容体として機能する
- Author(s)
  ○ 水本秀二, 高橋潤, 菅原一幸
- Organizer
  第３１回日本糖質学会年会
- Place of Presentation
  鹿児島市民ホール(鹿児島市）
- Data Source
  KAKENHI-PROJECT-23390016

1. YAMADA Shuhei (70240017)

# of Collaborated Projects: 10 results

# of Collaborated Products: 174 results
2. SUGAHARA Kazuyuki (60154449)

# of Collaborated Projects: 8 results

# of Collaborated Products: 161 results
3. KOSHO Tomoki (90276311)

# of Collaborated Projects: 6 results

# of Collaborated Products: 50 results
4. YOSHIZAWA TAKAHIRO (40713392)

# of Collaborated Projects: 5 results

# of Collaborated Products: 27 results
5. MIYAKE Noriko (40523494)

# of Collaborated Projects: 4 results

# of Collaborated Products: 21 results
6. IKEGAWA Shiro (30272496)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
7. MATSUMOTO Naomichi (80325638)

# of Collaborated Projects: 3 results

# of Collaborated Products: 22 results
8. 岳鳳鳴 (20532865)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. Janecke Andreas

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
10. YAMASHITA Tadashi (30220338)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 角田佳充 (00314360)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 岡田尚巳 (00326828)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 野村義宏 (10228372)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
14. 松本健一 (30202328)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
15. 上原将志 (30748108)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 渡邉敬文 (50598216)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
17. 高橋淳 (60345741)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
18. 宮田真路 (60533792)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. 高野亨子 (70392420)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 笠原優子 (90391911)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
21. 山口智美 (90802835)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 林正徳 (20624703)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 古市達哉 (30392103)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
24. 岡村匡史 (00333790)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. BASAPPA

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. YIP George W.C.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. STEFAN Mundlos

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
28. LIHADH Al-gazali

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
29. KATRIN Hoffmann

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. ANDREAS Janecke

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
31. Nürnberg Peter

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. Kennerknecht Ingo

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
33. Vodopiutz Julia

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. Kornak Uwe

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. WATANABE Kota

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
36. 岡田尚已

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
37. 武田和樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
38. 寺井崇二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MIZUMOTO Shuji 水本 秀二

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Pathogenic mechanisms of hereditary neurological, immune, skeletal disorders caused by mutations in UDP metabolic enzymePrincipal Investigator

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Crosstalk of proteoglycan and filamin and their genetic disordersPrincipal Investigator

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Mechanism of biosynthesis of glycosaminoglycan by Golgin, and its hereditary bone and skin disordersPrincipal Investigator

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Roles of chondroitin sulfate interacting with RAGE involved in tumor and Alzheimer's diseasePrincipal Investigator

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Pathogenic mechanisms of the bone diseases caused by defect in chondroitin sulfate biosynthesisPrincipal Investigator

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MIZUMOTO Shuji 水本秀二