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Takeuchi Hiroki  竹内 洋輝

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TAKEUCHI HIROKI  竹内 洋輝

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Researcher Number 40572186
Other IDs
Affiliation (Current) 2020: 大阪大学, 歯学部附属病院, 講師
Affiliation (based on the past Project Information) *help 2018 – 2020: 大阪大学, 歯学研究科, 助教
2017: 大阪大学, 歯学研究科(研究院), 助教
2016: 大阪大学, 歯学研究科, 助教
2015: 大阪大学, 歯学研究科(研究院), 助教
2015: 大阪大学, 歯学研究科(研究院), 特任助教
2013 – 2014: 大阪大学, 歯学部附属病院, 医員
Review Section/Research Field
Principal Investigator
Morphological basic dentistry / Pathobiological dentistry/Dental radiology / Basic Section 57020:Oral pathobiological science-related
Except Principal Investigator
Social dentistry / Basic Section 57080:Social dentistry-related / Medium-sized Section 57:Oral science and related fields
Keywords
Principal Investigator
歯学 / 歯周病 / Porphyromonas gingivalis / 分子生物学 / 組織工学 / 細菌学
Except Principal Investigator
歯周病 / P. gingivalis / メンブレントラフィック / 歯学 … More / メタボロミクス / Porphyromonas gingivalis / メタボローム解析 / 歯周炎 / バイオフィルム / F. nucleatum / S. gordonii / 細胞内感染 / 予測歯科 / 発症リスク / 細胞内侵入 / 生活習慣 / メタボローム研究 / 細菌感染 / バイオフイルム / ディスバイオーシス / Porphyromonas gingivitis / Streptococcus gordonii / Fusobacterium nucleatum / プロテオミクス / 細菌 / 微生物 / 発現制御 / 口腔細菌叢 / エコロジカルシフト / バクテリオファージ / 細胞内寄生 / Rab14 / RalA / VAMP2 / VAMP2 / 細菌の細胞侵入 / 唾液 / 歯肉溝浸出液 / 動的ネットワークバイオマーカー / 生活習慣病 / 細胞内定着 / 細胞内輸送 / ポリアミン / 組織内定着 Less
  • Research Projects

    (9 results)
  • Research Products

    (34 results)
  • Co-Researchers

    (13 People)
  •  Detection of adult lifestyle-related presymptomatic disease by a dynamic network marker derived from oral specimensOngoing

    • Principal Investigator
      久保庭 雅恵
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 57080:Social dentistry-related
    • Research Institution
      Osaka University
  •  歯周病の発症につながる歯肉上皮バリア責任遺伝子の解析Principal InvestigatorOngoing

    • Principal Investigator
      竹内 洋輝
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57020:Oral pathobiological science-related
    • Research Institution
      Osaka University
  •  Molecular basis of colonization of periodontal pathogen into periodontal tissuesOngoing

    • Principal Investigator
      天野 敦雄
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 57:Oral science and related fields
    • Research Institution
      Osaka University
  •  The destructive mechanisms of epihthelial barrier funtion by peirodontal bacteria in membrane trafficPrincipal Investigator

    • Principal Investigator
      Takeuchi Hiroki
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Osaka University
  •  Proposal of novel etiology of periodontal infection: Intratissue infection

    • Principal Investigator
      Amano Atsuo
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Social dentistry
    • Research Institution
      Osaka University
  •  Mechanism analysis for evasion of periodontal pathogen from host innate immunityPrincipal Investigator

    • Principal Investigator
      Takeuchi Hiroki
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Osaka University
  •  Development of a novel method to prevent an ecological shift in oral polymicrobial biofilms by using bacteriophage therapy.

    • Principal Investigator
      KUBONIWA Masae
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Social dentistry
    • Research Institution
      Osaka University
  •  Establishment of the periodontitis onset risk rating system for the realization of predictive dentistry

    • Principal Investigator
      Amano Atsuo
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Social dentistry
    • Research Institution
      Osaka University
  •  Analysis of intracellular localization of periodontal pathogen in gingival epithelial cellsPrincipal Investigator

    • Principal Investigator
      TAKEUCHI HIROKI
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Osaka University

All 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

  • [Journal Article] Association between mastication-related factors and the prevalence of dementia in Korean elderly women visiting senior centres2019

    • Author(s)
      Takeuchi Hiroki、Sasaki Naoko、Yamaga Shunsuke、Kuboniwa Masae、Matsusaki Michiya、Amano Atsuo
    • Journal Title

      PLOS Pathogens

      Volume: 15

    • DOI

      10.1371/journal.ppat.1008124

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K10085, KAKENHI-PROJECT-17H00864, KAKENHI-PROJECT-18H04068, KAKENHI-PROJECT-20K20393
  • [Journal Article] dhesion and invasion of gingival epithelial cells by Porphyromonas gulae2019

    • Author(s)
      Hiroaki Inaba, Ryota Nomura, Yukio Kato, Hiroki Takeuchi, Atsuo Amano, Fumitoshi Asai, Kazuhiko Nakano, Richard J. Lamont, Michiyo Matsumoto-Nakano
    • Journal Title

      PLoS One

      Volume: 14

    • DOI

      10.1371/journal.pone.0213309

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11612, KAKENHI-PROJECT-19K10085, KAKENHI-PROJECT-18H04068, KAKENHI-PROJECT-20K20393
  • [Journal Article] Dual lifestyle of Porphyromonas gingivalis in biofilm and gingival cells.2016

    • Author(s)
      Sakanaka A, Takeuchi H, Kuboniwa M, Amano A*
    • Journal Title

      Microbial Pathogenesis

      Volume: 94 Pages: 42-47

    • DOI

      10.1016/j.micpath.2015.10.003

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26253094, KAKENHI-PROJECT-15H05057, KAKENHI-PROJECT-16J07311, KAKENHI-PROJECT-25293426, KAKENHI-PROJECT-15K15773, KAKENHI-PROJECT-16K15853
  • [Journal Article] Intracellular periodontal pathogen exploits recycling pathway to exit from infected cells.2016

    • Author(s)
      Takeuchi H, Takada A, Kuboniwa M, Amano A。
    • Journal Title

      Cellular Microbiology

      Volume: in press Pages: 928-948

    • DOI

      10.1111/cmi.12551

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15J05275, KAKENHI-PROJECT-26253094, KAKENHI-PROJECT-15H05057, KAKENHI-PROJECT-15K15773, KAKENHI-PROJECT-15K20360, KAKENHI-PROJECT-16K15853
  • [Journal Article] Arginine-Ornithine Antiporter ArcD Controls Arginine Metabolism and Interspecies Biofilm Development of Streptococcus gordonii.2015

    • Author(s)
      Sakanaka A, Kuboniwa M, Takeuchi H, Hashino E, Amano A
    • Journal Title

      Journal of Biological Chemistry

      Volume: 290 Pages: 21185-21198

    • DOI

      10.1074/jbc.m115.644401

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K15773, KAKENHI-PROJECT-15K20360, KAKENHI-PROJECT-15K20642, KAKENHI-PROJECT-26253094, KAKENHI-PROJECT-15H05057, KAKENHI-PROJECT-15J05275
  • [Journal Article] 歯周病の発症と全身疾患:21世紀の新展開2015

    • Author(s)
      天野敦雄,竹内洋輝,久保庭雅恵
    • Journal Title

      日本臨床腸内微生物学会誌

      Volume: 17 Pages: 26-32

    • Data Source
      KAKENHI-PROJECT-26253094
  • [Journal Article] 歯周病の発症と全身疾患:21世紀の新展開.2015

    • Author(s)
      天野敦雄、竹内洋輝、久保庭雅恵
    • Journal Title

      日本臨床腸内微生物学会誌

      Volume: 17 Pages: 26-32

    • Data Source
      KAKENHI-PROJECT-15H05057
  • [Journal Article] Transcellular invasive mechanisms of Porphyromonas gingivalis in host-parasite interactions.2014

    • Author(s)
      Amano A, Kuboniwa M, Takeuchi H.
    • Journal Title

      Journal of Oral Biosciences

      Volume: 56

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25893120
  • [Journal Article] Transcellular invasive mechanisms of Porphyromonas gingivalis in host-parasite interactions2014

    • Author(s)
      Amano A, Kuboniwa M, Takeuchi H
    • Journal Title

      Journal of Oral Bioscience

      Volume: 56 Pages: 58-62

    • DOI

      10.1016/j.job.2014.02.001

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24593150, KAKENHI-PROJECT-26253094
  • [Journal Article] The periodontal pathogen Porphyromonas gingivalis exits from gingival epithelial cell via recycling pathways2014

    • Author(s)
      Takeuchi H, Amano A
    • Journal Title

      Journal of Osaka University Dental Society

      Volume: 59 Pages: 13-15

    • NAID

      120005602792

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26253094
  • [Journal Article] Transcellular invasive mechanisms of Porphyromonas gingivalis in host-parasite interactions2014

    • Author(s)
      Atsuo Amano, Masae Kuboniwa, Hiroki Takeuchi
    • Journal Title

      Journal of Oral Biosciences

      Volume: 56 Pages: 58-62

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25893120
  • [Presentation] Porphyromonas gingivalis induces penetration of lipopolysaccharide and peptidoglycan through the gingival epithelial cell monolayer via degradation of junctional adhesion molecule 12019

    • Author(s)
      Takeuchi H, Amano A
    • Organizer
      4th Meeting of the IADR Asia Pacific Region
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H04068
  • [Presentation] Porphyromonas gingivalis に感染した歯肉上皮細胞におけるJAM1 タンパク質の分解2019

    • Author(s)
      竹内洋輝、天野敦雄
    • Organizer
      第60回歯科基礎医学会
    • Data Source
      KAKENHI-PROJECT-17K17083
  • [Presentation] 毛細血管網を有する歯周病菌感染組織モデル構築と感染防御機構の解明2019

    • Author(s)
      佐々木尚子,竹内洋輝,北野史朗,入江新司,天野敦雄,松崎典弥
    • Organizer
      第41回日本バイオマテリアル学会
    • Data Source
      KAKENHI-PROJECT-18H04068
  • [Presentation] Porphyromonas gingivalis induces penetration of lipopolysaccharide and peptidoglycan through gingival epithelial cell monolayer via degradation of junctional adhesion molecule 1.2019

    • Author(s)
      Takeuchi H, Amano A.
    • Organizer
      4th Meeting of the International Association for Dental Research, Asia Pacific Region
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K10085
  • [Presentation] Porphyromonas gingivalisに感染した歯肉上皮細胞における CXADR タンパク質の分解2019

    • Author(s)
      山賀 俊介,竹内 洋輝,天野 敦雄
    • Organizer
      近畿・中国・四国口腔衛生学会総会
    • Data Source
      KAKENHI-PROJECT-18H04068
  • [Presentation] Leukocyte adhesion deficiency-1 責任遺伝子のノックダウンによる歯肉上皮細胞の形態学的解析2019

    • Author(s)
      山賀俊介、竹内洋輝、天野敦雄
    • Organizer
      2018年度近畿・中国・四国口腔衛生学会
    • Data Source
      KAKENHI-PROJECT-17K17083
  • [Presentation] Leukocyte adhesion deficiency-1 責任遺伝子のノックダウンによる歯肉上皮細胞の形態学的解析2018

    • Author(s)
      山賀俊介、竹内洋輝、天野敦雄
    • Organizer
      第29回近畿・中国・四国口腔衛生学会総会
    • Data Source
      KAKENHI-PROJECT-18H04068
  • [Presentation] 歯周病を随伴する遺伝疾患の細胞モデルの作成2018

    • Author(s)
      竹内洋輝、山賀俊介、天野敦雄
    • Organizer
      第67回日本口腔衛生学会・総会、2018年5月20日,札幌市
    • Data Source
      KAKENHI-PROJECT-18H04068
  • [Presentation] Porphyromonas gingivalis に感染した歯肉上皮細胞におけるJAM1タンパクの分解2018

    • Author(s)
      竹内洋輝,天野敦雄
    • Organizer
      第60回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-18H04068
  • [Presentation] Involvement of Rab4A-relative factors in intracellular trafficking of Porphyromonas gingivalis in gingival epithelial cells2017

    • Author(s)
      Takeuchi H, Amano A
    • Organizer
      PG Melbourne 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26253094
  • [Presentation] Involvement of Rab4A-relative factors in intracellular trafficking of Porphyromonas gingivalis in gingival epithelial cells2017

    • Author(s)
      Hiroki Takeuchi, Atsuo Amano
    • Organizer
      Pg Melbourne 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K17083
  • [Presentation] Involvement of Rab4A-relative factors in intracellular trafficking of Porphyromonas gingivalis in gingival epithelial cells2017

    • Author(s)
      Takeuchi H, Amano A
    • Organizer
      PG Melbourne 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15853
  • [Presentation] 歯肉上皮細胞に侵入したPorphyromonas gingivalis の細胞内動態の解析2016

    • Author(s)
      竹内洋輝, 目絵理子,天野敦雄
    • Organizer
      第27 回近畿・中国・四国口腔衛生学会
    • Place of Presentation
      大阪大学(大阪府吹田市)
    • Year and Date
      2016-10-02
    • Data Source
      KAKENHI-PROJECT-15K20360
  • [Presentation] 歯肉上皮細胞に侵入したPorphyromonas gingivalis の細胞内動態の解析2015

    • Author(s)
      竹内 洋輝, 天野 敦雄
    • Organizer
      第26 回近畿・中国・四国口腔衛生学会
    • Place of Presentation
      山口県歯科医師会館(山口県山口市)
    • Year and Date
      2015-09-27
    • Data Source
      KAKENHI-PROJECT-15K20360
  • [Presentation] PotDがStreptococcus gordoniiの酸性環境中でのバイオフィルム形成に及ぼす影響2014

    • Author(s)
      坂中哲人、久保庭雅恵、竹内洋輝、橋野恵衣、天野敦雄
    • Organizer
      第25回近畿・中国・四国口腔衛生学会
    • Place of Presentation
      兵庫県歯科医師会館(兵庫県神戸市)
    • Year and Date
      2014-10-05
    • Data Source
      KAKENHI-PROJECT-26253094
  • [Presentation] Involvement of Rab4A and VAMP2 in intracellular Porphyromonas gingivalis in gingival epithelial cells2014

    • Author(s)
      Takeuchi H, Amano A
    • Organizer
      62nd Annual Meeting of Japanese Association for Dental Research
    • Place of Presentation
      KKRホテル大阪(大阪府大阪市)
    • Year and Date
      2014-12-05
    • Data Source
      KAKENHI-PROJECT-26253094
  • [Presentation] Involvement of VAMP2 in intracellular localization of Porphyromonas gingivalis2014

    • Author(s)
      Takeuchi H, Takada A, Amano A
    • Organizer
      International Association for Dental Research General Session & Exhibition
    • Place of Presentation
      ケープタウン(南アフリカ)
    • Year and Date
      2014-06-28
    • Data Source
      KAKENHI-PROJECT-26253094
  • [Presentation] Exit of intracellular Porphyromonas gingivalis from gingival epithelial cells is mediated by endocytic recycling pathway2014

    • Author(s)
      Hiroki Takeuchi
    • Organizer
      The 116th Meeting of the Osaka University Dental Society
    • Place of Presentation
      Osaka, Japan
    • Year and Date
      2014-07-04
    • Data Source
      KAKENHI-PROJECT-25893120
  • [Presentation] Involvement of VAMP2 in intracellular localization of Porphyromonas gingivalis in recycling endosomes2014

    • Author(s)
      Takeuchi H, Amano A
    • Organizer
      第56回 歯科基礎医学会学術大会・総会
    • Place of Presentation
      福岡国際会議場(福岡県福岡市)
    • Year and Date
      2014-06-27
    • Data Source
      KAKENHI-PROJECT-26253094
  • [Presentation] A putative arginine-ornithine antiporter ArcD in Streptococcus gordonii controls de novo arginine biosynthesis, low pH tolerance and biofilm formation2014

    • Author(s)
      Sakanaka A, Kuboniwa M, Takeuchi H, Hashino E, Amano A
    • Organizer
      EMBO meeting
    • Place of Presentation
      パリ(フランス)
    • Year and Date
      2014-09-04
    • Data Source
      KAKENHI-PROJECT-26253094
  • [Presentation] Involvement of VAMP2 in intracellular localization of Porphyromonas gingivalis

    • Author(s)
      Hiroki Takeuchi, Akihiko Takada, Atsuo Amano
    • Organizer
      2014 International Association for Dental Research General Session & Exibition
    • Place of Presentation
      Cape Town, South Africa
    • Year and Date
      2014-06-25 – 2014-06-28
    • Data Source
      KAKENHI-PROJECT-25893120
  • [Presentation] Involvement of Rab4A and VAMP2 in intracellular Porphyromonas gingivalis in gingival epithelial cells

    • Author(s)
      Hiroki Takeuchi, Atsuo Amano
    • Organizer
      The 62nd Annual Meeting of Japanese Association for Dental Research
    • Place of Presentation
      Osaka, Japan
    • Year and Date
      2014-12-04 – 2014-12-05
    • Data Source
      KAKENHI-PROJECT-25893120
  • [Presentation] Involvement of VAMP2 in Porphyromonas gingivalis in recycling endosomes

    • Author(s)
      Hiroki Takeuchi, Atsuo Amano
    • Organizer
      The 56th Annual Meeting of Japanese Association for Oral Biology
    • Place of Presentation
      Fukuoka, Japan
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-25893120
  • 1.  Amano Atsuo (50193024)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 22 results
  • 2.  KUBONIWA Masae (00303983)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 9 results
  • 3.  SAKANAKA Akito (90815557)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 4.  小島 美樹 (20263303)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  橋野 恵衣 (90614553)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 6.  関根 伸一 (70506344)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  永田 英樹 (50260641)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  野崎 一徳 (40379110)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  玉川 裕夫 (50127255)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  松崎 典弥
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  佐々木 東
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  仲野 道代
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  稲葉 裕明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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