HASHINO Ei 橋野恵衣

Researcher Number	90614553
Affiliation (based on the past Project Information) *help	2016 – 2018: 大阪大学, 歯学研究科, 招へい教員 2017: 大阪大学, 歯学部附属病院, 特任助教 2015: 大阪大学, 歯学研究科(研究院), 招へい教員 2015: 大阪大学, 歯学研究科(研究院), 研究員 2014: 大阪大学, 歯学部附属病院, 特任助教 … More 2013 – 2014: 大阪大学, 歯学部附属病院, 助教 2012: 大阪大学, 歯学部附属病院, 特任助教 2011: 大阪大学, 歯学部附属病院, 医員 Less
Review Section/Research Field	Principal Investigator Social dentistry Except Principal Investigator Social dentistry
Keywords	Principal Investigator メタボローム解析 / 歯周病予防剤 / マイクロビオーム / タガトース / 歯周病 / 希少糖 / プロテオーム解析 / 歯周病原性バイオフィルム / Filifactor alocis / Porphyromonas gingivalis / バイオフィルム / 歯周病細菌 / 糖アルコール … More Except Principal Investigator … More 歯周病 / PCR / 歯周病細菌 / 検出システム / 口腔微生物 / 予防歯科学 / 細菌感染 / 歯学 / メタボローム研究 / 生活習慣 / 細胞内侵入 / 発症リスク / 予測歯科 / 細胞内感染 / S. gordonii / F. nucleatum / メンブレントラフィック / バイオフィルム / P. gingivalis / 歯周炎 / メタボロミクス / 口腔細菌 / アメリカ合衆国 / 国際情報交換 / ポリアミン / メタボローム / パラアミノ安息香酸 / Porphyromonas gingivalis / 歯周病原性菌 / バイオフイルム Less

Evaluation of the probiotic effect of tagatose on periodontal inflammation.Principal Investigator
- Principal Investigator
  
  EI HASHINO
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Social dentistry
- Research Institution
  Osaka University
Establishment of the periodontitis onset risk rating system for the realization of predictive dentistry
- Principal Investigator
  
  Amano Atsuo
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Social dentistry
- Research Institution
  Osaka University
Development of fast detection system for oral microorganism which aims clinical application in infectious oral deiseases
- Principal Investigator
  
  Nagata Hideki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Social dentistry
- Research Institution
  Osaka University
Molecular basis of phenotype alteration between planktonic and biofilm in Porphyromonas gingivalis
- Principal Investigator
  
  KUBONIWA Masae
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Social dentistry
- Research Institution
  Osaka University
Effects of polyols on periodontopathic biofilm developmentPrincipal Investigator
- Principal Investigator
  
  HASHINO Ei
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Social dentistry
- Research Institution
  Osaka University

All 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] Distinct signatures of dental plaque metabolic byproducts dictated by periodontal inflammatory status.2017
- Author(s)
  Sakanaka A, Kuboniwa M*, Hashino E, Bamba T, Fukusaki E, Amano A
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 42818-42818
- DOI
  10.1038/srep42818
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05057, KAKENHI-PROJECT-16J07311, KAKENHI-PROJECT-26505007, KAKENHI-PROJECT-15K15773, KAKENHI-PROJECT-15K20642, KAKENHI-PROJECT-26253094, KAKENHI-PROJECT-16K15853
[Journal Article] Prediction of periodontal inflammation via metabolic profiling of saliva2016
- Author(s)
  Kuboniwa M*, Sakanaka A, Hashino E, Bamba T, Fukusaki E, Amano A
- Journal Title
  
  Journal of Dental Research
  
  Volume: 95 Issue: 12 Pages: 1381-1386
- DOI
  10.1177/0022034516661142
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26253094, KAKENHI-PROJECT-15H05057, KAKENHI-PROJECT-16J07311, KAKENHI-PROJECT-15K15773, KAKENHI-PROJECT-16K15853, KAKENHI-PROJECT-15K20642
[Journal Article] Arginine-ornithine antiporter ArcD in Streptococcus gordonii controls arginine metabolism and biofilm development with Fusobacterium nucleatum by ornithine cross-feeding.2015
- Author(s)
  Sakanaka A, Kuboniwa M, Takeuchi H, Hashino E, Amano A
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 290 Issue: 35 Pages: 21185-21198
- DOI
  10.1074/jbc.m115.644401
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15773, KAKENHI-PROJECT-15K20360, KAKENHI-PROJECT-15K20642, KAKENHI-PROJECT-26253094, KAKENHI-PROJECT-15H05057, KAKENHI-PROJECT-15J05275
[Journal Article] Erythritol alters microstructures and metabolomic profiles of biofilm composed of Streptococcus gordonii and Porphyromonas gingivalis2013
- Author(s)
  Hashino E, Kuboniwa M, Alghamdi S, Yamaguchi M, Yamamoto R, Cho H, Amano A
- Journal Title
  
  Molecular Oral Microbiology
  
  Volume: 28(6) Issue: 6 Pages: 435-451
- DOI
  10.1111/omi.12037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390477, KAKENHI-PROJECT-24593150, KAKENHI-PROJECT-24659933
[Presentation] Detecting Transition from Periodontal Health to Disease: A Salivary Metabolomics Perspective2017
- Author(s)
  1.坂中哲人, 橋野恵衣, 久保庭雅恵
- Organizer
  第4回「疾患における代謝産物の解析および代謝制御に基づく革新的医療基盤技術の創出」研究領域AMED-CREST・さきがけ合同領域会議
- Data Source
  KAKENHI-PROJECT-15K20642
[Presentation] 歯周病重篤度評価における唾液代謝物カダベリンの有用性2016
- Author(s)
  坂中哲人, 久保庭雅恵, 橋野恵衣, 天野敦雄
- Organizer
  第27回近畿・中国・四国口腔衛生学会・総会
- Place of Presentation
  大阪大学（大阪府吹田市）
- Year and Date
  2016-10-02
- Data Source
  KAKENHI-PROJECT-15K20642
[Presentation] Salivary microbially-derived metabolic signatures are linked to periodontal inflammatory status2016
- Author(s)
  Sakanaka A, Kuboniwa M, Hashino E, Fukusaki E, Amano A
- Organizer
  94th IADR General Meeting
- Place of Presentation
  COEX Convention & Exhibition Center, Seoul, Korea
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253094
[Presentation] Relationship between tongue coating and salivary metabolome2016
- Author(s)
  Sakanaka A, Kuboniwa M, Hashino E, Amano A
- Organizer
  12th International Conference of Asian Academy of Preventive Dentistry
- Place of Presentation
  東京都千代田区東京医科歯科大学
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253094
[Presentation] Relationship between tongue coating and salivary metabolome.2016
- Author(s)
  Sakanaka A, Kuboniwa M, Hashino E, Amano A
- Organizer
  12th International Conference of Asian Academy of Preventive Dentistry
- Place of Presentation
  東京医科歯科大学（東京都文京区）
- Year and Date
  2016-05-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20642
[Presentation] Salivary microbially-derived metabolic signatures are linked to periodontal inflammatory status.2016
- Author(s)
  Sakanaka A, Kuboniwa M, Hashino E, Fukusaki E, Amano A
- Organizer
  94th IADR General Meeting
- Place of Presentation
  Seoul, Korea
- Year and Date
  2016-06-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20642
[Presentation] 唾液メタボローム解析を用いた歯周組織由来の慢性炎症重症度評価モデルの構築2015
- Author(s)
  橋野恵衣、久保庭雅恵、坂中哲人、関根伸一、永田英樹、天野敦雄
- Organizer
  第64回日本口腔衛生学会・総会
- Place of Presentation
  つくば国際会議場（茨城県つくば市）
- Year and Date
  2015-05-27
- Data Source
  KAKENHI-PROJECT-15K20642
[Presentation] A putative arginine-ornithine antiporter ArcD in Streptococcus gordonii controls de novo arginine biosynthesis, low pH tolerance and biofilm formation2014
- Author(s)
  Sakanaka A, Kuboniwa M, Takeuchi H, Hashino E, Amano A
- Organizer
  EMBO meeting
- Place of Presentation
  Paris (France)
- Year and Date
  2014-09-04
- Data Source
  KAKENHI-PROJECT-24593150
[Presentation] Effect of arginine metabolic pathways on periodontopathic biofilms formation2014
- Author(s)
  Hashino E, Kuboniwa M, Sakanaka A, Amano A
- Organizer
  Metabolomics 2014
- Place of Presentation
  Tsuruoka (Japan)
- Year and Date
  2014-06-25
- Data Source
  KAKENHI-PROJECT-24593150
[Presentation] A putative arginine-ornithine antiporter ArcD in Streptococcus gordonii controls de novo arginine biosynthesis, low pH tolerance and biofilm formation2014
- Author(s)
  Sakanaka A, Kuboniwa M, Takeuchi H, Hashino E, Amano A
- Organizer
  EMBO meeting
- Place of Presentation
  パリ（フランス）
- Year and Date
  2014-09-04
- Data Source
  KAKENHI-PROJECT-26253094
[Presentation] 口腔清掃状態の唾液メタボロームへの影響2014
- Author(s)
  坂中哲人、久保庭雅恵、橋野恵衣、天野敦雄
- Organizer
  第63回口腔衛生学会
- Place of Presentation
  熊本市民会館崇城大学ホール／熊本市国際交流会館（熊本県・熊本市）
- Year and Date
  2014-05-30
- Data Source
  KAKENHI-PROJECT-24593150
[Presentation] PotDがStreptococcus gordoniiの酸性環境中でのバイオフィルム形成に及ぼす影響2014
- Author(s)
  坂中哲人、久保庭雅恵、竹内洋輝、橋野恵衣、天野敦雄
- Organizer
  第25回近畿・中国・四国口腔衛生学会
- Place of Presentation
  兵庫県歯科医師会館（兵庫県・神戸市）
- Year and Date
  2014-10-05
- Data Source
  KAKENHI-PROJECT-24593150
[Presentation] PotDがStreptococcus gordoniiの酸性環境中でのバイオフィルム形成に及ぼす影響2014
- Author(s)
  坂中哲人、久保庭雅恵、竹内洋輝、橋野恵衣、天野敦雄
- Organizer
  第25回近畿・中国・四国口腔衛生学会
- Place of Presentation
  兵庫県歯科医師会館（兵庫県神戸市）
- Year and Date
  2014-10-05
- Data Source
  KAKENHI-PROJECT-26253094
[Presentation] Metabolome profiles of polyol-treated Filifactor alocis.2013
- Author(s)
  Hashino, E.
- Organizer
  2nd meeting of IADR-Asia Pacific Region
- Place of Presentation
  Bangkok, Thailand
- Data Source
  KAKENHI-PROJECT-24593150
[Presentation] Metabolome profiles of polyol-treated Filifactor alocis2013
- Author(s)
  Ei Hashino
- Organizer
  2nd Meeting of the International Association of Dental Research-Asia Pacific Region
- Place of Presentation
  Bangkok, Thailand
- Data Source
  KAKENHI-PROJECT-23890112
[Presentation] Metabolome profiles of polyols-treated Filifactor alocis2013
- Author(s)
  Hashino E, Kuboniwa M, Alghamdi A S, Amano A
- Organizer
  2nd Meeting of the International Association of Dental Research-Asia Pacific Region
- Place of Presentation
  Bangkok, Thailand
- Data Source
  KAKENHI-PROJECT-23890112
[Presentation] Porphyromonas gingivalis biofilm dispersion triggered by exogenous polyamines.2012
- Author(s)
  Kuboniwa M, Tomio A, Alghamdi A S, Hashino E, Bamba T, Fukusaki E, Amano A
- Organizer
  Biofilms 5
- Place of Presentation
  Paris, France
- Data Source
  KAKENHI-PROJECT-23890112
[Presentation] 歯肉由来 iPS 細部を利用した樹状細胞は抗原特異的な抗体産生を誘導する2012
- Author(s)
  関根伸一, 橋野恵衣, 永田英樹, 天野敦雄
- Organizer
  第61回日本口腔衛生学会・総会
- Place of Presentation
  横須賀
- Year and Date
  2012-05-27
- Data Source
  KAKENHI-PROJECT-23890112
[Presentation] Alteration of Streptococcus gordonii metabolomic profiles under sorbitol stress.2012
- Author(s)
  Hashino E, Kuboniwa M, Sekine S, Alghamdi A S, Amano A
- Organizer
  The 10th International Conference of Asian Academy of Preventive Dentistry
- Place of Presentation
  Ulaambaatar, Mongolia
- Data Source
  KAKENHI-PROJECT-23890112
[Presentation] テルペノイド骨格生合成阻害剤が口腔バイオフィルムに及ぼす影響.2012
- Author(s)
  Alghamdi A S, 久保庭雅恵, 橋野恵衣, 天野敦雄
- Organizer
  第23回近畿・中国・四国口腔衛生学会総会
- Place of Presentation
  大津
- Year and Date
  2012-10-07
- Data Source
  KAKENHI-PROJECT-23890112
[Presentation] Effects of polyamines on single species biofilms of Porphyromonas gingivalis and Streptococcus gordonii2012
- Author(s)
  Alghamdi A S, 久保庭雅恵, 橋野恵衣, 冨尾紋子, 馬場健史, 福崎英一郎, 天野敦雄
- Organizer
  第54回歯科基礎医学会学術大会
- Place of Presentation
  郡山
- Year and Date
  2012-09-14
- Data Source
  KAKENHI-PROJECT-23890112
[Presentation] Porphyromonas gingivalis GAPDH はStreptococcus oralis GAPDH に特異的に結合する2011
- Author(s)
  前田和彦,久保庭雅恵,小島美樹,黒田裕美子,橋野恵衣,東江正裕,永田英樹
- Organizer
  第60回日本口腔衛生学会・総会
- Place of Presentation
  千葉
- Year and Date
  2011-10-09
- Data Source
  KAKENHI-PROJECT-23890112
[Presentation] パラアミノ安息香酸によるPorphyromonas gingivalis の菌体内メタボロームプロファイルの変化2011
- Author(s)
  久保庭雅恵,Alghamdi Samar,橋野恵衣,天野敦雄
- Organizer
  第53回歯科基礎医学会学術大会・総会
- Place of Presentation
  岐阜
- Year and Date
  2011-10-02
- Data Source
  KAKENHI-PROJECT-23890112
[Presentation] メタボロミクス解析によるエリスリトール存在下でのPorphyromonas gingivalis代謝プロファイルの検討2011
- Author(s)
  橋野恵衣
- Organizer
  第60回日本口腔衛生学会・総会
- Place of Presentation
  日本大学松戸歯学部(千葉県)
- Year and Date
  2011-10-10
- Data Source
  KAKENHI-PROJECT-23890112
[Presentation] Metabolome profiles in Porphyromonas gingivalis under erythritol stress2011
- Author(s)
  Ei Hashino
- Organizer
  59th Annual Meeting of Japanese Association for Dental Research
- Place of Presentation
  Hiroshima (Japan)
- Year and Date
  2011-10-08
- Data Source
  KAKENHI-PROJECT-23890112
[Presentation] Metabolome profiles in Streptococcus gordonii co-cultured with Porphyromonas gingivalis2011
- Author(s)
  Kuboniwa M, Kuroda Y, Hashino E, Alghamdi S, Hackett M, Lamont RJ, Amano A
- Organizer
  International Union of Microbiological Societies 2011 Congress
- Place of Presentation
  Sapporo, Japan
- Year and Date
  2011-09-10
- Data Source
  KAKENHI-PROJECT-23890112
[Presentation] Erythritol alters metabolome profiles in periodontopathic biofilm-forming microbes2011
- Author(s)
  Hashino E
- Organizer
  The Second Osaka Mahidol Chulalongkorn Joint Symposium
- Place of Presentation
  Bangkok, Thailand
- Year and Date
  2011-10-25
- Data Source
  KAKENHI-PROJECT-23890112
[Presentation] Metabolome profiles in Porphyromonas gingivalisstimulated with exogenous para-aminobenzoate2011
- Author(s)
  Kuboniwa M, Alghamdi S, Hashino E, Lamont RJ, Amano A
- Organizer
  7th International Conference of the Metabolomics Society
- Place of Presentation
  Caines, Australia
- Year and Date
  2011-06-29
- Data Source
  KAKENHI-PROJECT-23890112
[Presentation] Erythritol alters metabolome profiles in periodontopathic biofilm-forming microbes2011
- Author(s)
  Ei Hashino
- Organizer
  The Second Osaka Mahidol Chulalongkorn Joint Symposium
- Place of Presentation
  Bangkok (Thailand)(招待講演)
- Year and Date
  2011-10-25
- Data Source
  KAKENHI-PROJECT-23890112
[Presentation] メタボロミクス解析によるエリスリトール存在下でのPorphyromonas gingivalis代謝プロファイルの検討2011
- Author(s)
  橋野恵衣,久保庭雅恵,黒田裕美子,前田和彦,小島美樹,永田英樹,天野敦雄
- Organizer
  第60回日本口腔衛生学会・総会
- Place of Presentation
  千葉
- Year and Date
  2011-10-10
- Data Source
  KAKENHI-PROJECT-23890112
[Presentation] Metabolome profiles in Porphyromonas gingivalis under erythritol stress2011
- Author(s)
  Hashino E, Kuboniwa M, Amano A
- Organizer
  59th Annual Meeting of Japanese Association for Dental Research
- Place of Presentation
  Hiroshima, Japan
- Year and Date
  2011-10-08
- Data Source
  KAKENHI-PROJECT-23890112
[Presentation] Alteration of Streptococcus gordonii metabolomic profiles under sorbitol stress.
- Author(s)
  Hashino E
- Organizer
  10th International Conference of Asian Academy of Preventive Dentistry
- Place of Presentation
  Ulaanbaatar, Mongolia
- Data Source
  KAKENHI-PROJECT-24593150
[Presentation] マイクロチップPCRとキャピラリー電気泳動システムを用いた即時細菌検査システムの開発
- Author(s)
  関根伸一，泉井秀介，橋野恵衣，永田英樹，天野敦雄
- Organizer
  第64回日本口腔衛生学会・総会
- Place of Presentation
  つくば国際会議場
- Year and Date
  2015-05-27 – 2015-05-29
- Data Source
  KAKENHI-PROJECT-26670903
[Presentation] Alteration of Streptococcus gordonii metabolomic profiles under sorbitol stress
- Author(s)
  Ei Hashino
- Organizer
  10th International Conference of Asian Academy of Preventive Dentistry
- Place of Presentation
  Ulaanbaatar, Mongolia
- Data Source
  KAKENHI-PROJECT-23890112

1. KUBONIWA Masae (00303983)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
2. OJIMA Miki (20263303)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. AMANO Atsuo (50193024)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
4. FURUTA Nobumichi (50452446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. Nagata Hideki (50260641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 竹内洋輝 (40572186)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 関根伸一 (70506344)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 前田和彦 (00346165)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SAKANAKA Akito

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HASHINO Ei 橋野 恵衣

Research Projects

Research Products

Co-Researchers

Evaluation of the probiotic effect of tagatose on periodontal inflammation.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of the periodontitis onset risk rating system for the realization of predictive dentistry

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of fast detection system for oral microorganism which aims clinical application in infectious oral deiseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular basis of phenotype alteration between planktonic and biofilm in Porphyromonas gingivalis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effects of polyols on periodontopathic biofilm developmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Distinct signatures of dental plaque metabolic byproducts dictated by periodontal inflammatory status.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prediction of periodontal inflammation via metabolic profiling of saliva2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Arginine-ornithine antiporter ArcD in Streptococcus gordonii controls arginine metabolism and biofilm development with Fusobacterium nucleatum by ornithine cross-feeding.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Erythritol alters microstructures and metabolomic profiles of biofilm composed of Streptococcus gordonii and Porphyromonas gingivalis2013

Author(s)

Journal Title

DOI

Data Source

[Presentation] Detecting Transition from Periodontal Health to Disease: A Salivary Metabolomics Perspective2017

Author(s)

Organizer

Data Source

[Presentation] 歯周病重篤度評価における唾液代謝物カダベリンの有用性2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Salivary microbially-derived metabolic signatures are linked to periodontal inflammatory status2016

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Relationship between tongue coating and salivary metabolome2016

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Relationship between tongue coating and salivary metabolome.2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

HASHINO Ei 橋野恵衣