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Toshima Takeo  戸島 剛男

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TOSHIMA Takeo  戸島 剛男

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Researcher Number 40608965
Affiliation (Current) 2025: 九州大学, 大学病院, 講師
Affiliation (based on the past Project Information) *help 2025: 九州大学, 大学病院, 講師
2023: 九州大学, 大学病院, 講師
2020 – 2022: 九州大学, 大学病院, 助教
2019: 九州大学, 大学病院, 医員
2018: 九州大学, 医学研究院, 共同研究員 … More
2017: 九州大学, 大学病院, 助教
2016: 九州大学, 医学研究院, 共同研究員
2014 – 2015: 九州大学, 医学(系)研究科(研究院), 研究員
2013: 九州大学, 医学(系)研究科(研究院), 共同研究員
2012: 九州大学, 大学病院, 医員 Less
Review Section/Research Field
Principal Investigator
Digestive surgery / Basic Section 55020:Digestive surgery-related
Except Principal Investigator
Basic Section 55020:Digestive surgery-related / Basic Section 55010:General surgery and pediatric surgery-related / Digestive surgery
Keywords
Principal Investigator
オートファジー / 肝再生 / 肝移植 / 肝切除 / 肝臓 / 老化 / NET-CAGE / シングルセル解析 / GEX-ATAC / シングルセル解析 NET-CAGE … More / エンハンサー / 全ゲノムシークエンス / 膵癌 / 肝癌 / メタボローム解析 / 肝細胞代謝 / 代謝 / 肝細胞 / 脂肪肝 / 肝障害 … More
Except Principal Investigator
肝細胞癌 / 肝移植 / 生体肝移植 / 人工肝臓 / iPS細胞 / 肝不全 / VETC / capicua / オートファジー / 複合免疫療法 / 癌微小環境 / spatial transcriptome / metabolism / microenviroment / pancreatic cancer / ミトコンドリア / がん代謝 / 膵癌微小環境 / 薬剤耐性 / 再発機序 / HCC / ラット / 肝臓 / 肝細胞移植 / ドナー / グラフト / iPS-Heps / Scaffold / 大量培養 / 急性肝不全 / scaffold / 線維芽細胞 / EMT / マイクロアレイ解析 / Normal fibroblast / 網羅的解析 / Exsome / CAF / miR-150-3p / miRNA / 癌関連線維芽細胞 / エクソソーム / 分子機序 / 肝性脳症 / 門脈圧亢進症 / 肝硬変 / メタボローム解析 / 便移植 / 胆汁酸 / 短鎖脂肪酸 / 腸内細菌叢 / マイトファジー / 肝癌 / 類洞様血管構造 / 膵癌 / 再発 / HLA-Class II / HLA / HBVワクチン / ワクチン / B型肝炎ウイルス / 肝切除術 / ATP / 細胞老化 / 肝機能 / 肝切除 / 肝再生 / 肝臓外科学 Less
  • Research Projects

    (17 results)
  • Research Products

    (78 results)
  • Co-Researchers

    (33 People)
  •  肝移植後免疫抑制状態での肝癌再発を創出するがん免疫微小環境の革新的解明Principal Investigator

    • Principal Investigator
      戸島 剛男
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kyushu University
  •  生体肝移植後長期予後を目指した革新的なグラフト質的評価法の樹立

    • Principal Investigator
      萱島 寛人
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kyushu University
  •  Elucidation of the mechanism of metastasis and acquisition of malignancy in postoperative recurrence of hepatocellular carcinoma and construction of an innovative treatment strategy

    • Principal Investigator
      吉屋 匠平
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kyushu University
  •  膵がん微小環境を構築する細胞社会において免疫寛容に寄与するがん代謝機構の解明

    • Principal Investigator
      細田 清孝
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kyushu University
  •  免疫微小環境を標的とした高悪性度肝細胞癌に対する統合的治療戦略の開発

    • Principal Investigator
      古川 賢英
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Jikei University School of Medicine
  •  New treatment methods for liver failure by human iPS cells

    • Principal Investigator
      吉住 朋晴
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Kyushu University
  •  時・空間的シングルセル解析による膵がん細胞の悪性度獲得機構の解明と治療標的の同定Principal Investigator

    • Principal Investigator
      戸島 剛男
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kyushu University
  •  Development of the innovative treatment using self iPS cell for acute liver failure

    • Principal Investigator
      HARADA Noboru
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kyushu University
  •  Prevention of HBV recurrence by HBV vaccination based on SNP and allele of HLA class II

    • Principal Investigator
      YOSHIZUMI Tomoharu
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Kyushu University
  •  肝移植後肝細胞癌再発に対する機序解明と革新的治療戦略の構築

    • Principal Investigator
      吉屋 匠平
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kyushu University
  •  Autophagy and mitophagy in advanced hepatocellular carcinoma

    • Principal Investigator
      Ikegami Toru
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Jikei University School of Medicine
      Kyushu University
  •  Elucidation of the molecular mechanism of hepatic encephalopathy and development of innovative treatment by intestinal bacterial flora profiling

    • Principal Investigator
      soejima yuji
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Shinshu University
      Kyushu University
  •  New strategy of hepatocellular carcinoma treatment using exosomes exocrimned by cancer associated fibroblast

    • Principal Investigator
      HARADA Noboru
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kyushu University
  •  肝細胞の代謝制御におけるオートファジーの意義-KO細胞の網羅的メタボローム解析Principal Investigator

    • Principal Investigator
      戸島 剛男
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  Role of autophagy and Sirt-1 signal in liver regenerationPrincipal Investigator

    • Principal Investigator
      Toshima Takeo
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  Impact of autophagy in liver regenerationPrincipal Investigator

    • Principal Investigator
      TOSHIMA Takeo
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  The biological role of autophagy in liver regeneration in pathological condition.

    • Principal Investigator
      SHIRABE Ken
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University

All 2024 2023 2022 2020 2018 2017 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation Book

  • [Book] がんの新しいバイオマーカー2011

    • Author(s)
      戸島剛男、調憲
    • Total Pages
      365
    • Publisher
      技術情報協会
    • Data Source
      KAKENHI-PROJECT-22659245
  • [Journal Article] Tumor suppressive role of the epigenetic master regulator BRD3 in colorectal cancer.2024

    • Author(s)
      Hashimoto M, Masuda T, Nakano Y, Tobo T, Saito H, Koike K, Takahashi J, Abe T, Ando Y, Ozato Y, Hosoda K, Higuchi S, Hisamatsu Y, Toshima T, Yonemura Y, Hata T, Uemura M, Eguchi H, Doki Y, Mori M, Mimori K.
    • Journal Title

      Cancer Sci.

      Volume: - Issue: 6 Pages: 7538-7548

    • DOI

      10.1111/cas.16129

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08826, KAKENHI-PROJECT-22K08894, KAKENHI-PROJECT-22K09006, KAKENHI-PROJECT-23K08215, KAKENHI-PROJECT-21K07179, KAKENHI-PROJECT-23K24164
  • [Journal Article] Spatial and single-cell colocalisation analysis reveals MDK-mediated immunosuppressive environment with regulatory T cells in colorectal carcinogenesis2024

    • Author(s)
      Hashimoto Masahiro、Kojima Yasuhiro et. al.
    • Journal Title

      eBioMedicine

      Volume: 103 Pages: 105102-105102

    • DOI

      10.1016/j.ebiom.2024.105102

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K16991, KAKENHI-PROJECT-22K08894, KAKENHI-PROJECT-22K09006, KAKENHI-PROJECT-23K06662, KAKENHI-PROJECT-23K08215, KAKENHI-PROJECT-21K07179, KAKENHI-PLANNED-23H04938, KAKENHI-PROJECT-23K24164, KAKENHI-PROJECT-23K24941
  • [Journal Article] Implementable assay for monitoring minimum residual disease after radical treatment for colorectal cancer.2024

    • Author(s)
      Nakano T, Takao S, Dairaku K, Uno N, Low SA, Hashimoto M, Tsuda Y, Hisamatsu Y, Toshima T, Yonemura Y, Masuda T, Eto K, Ikegami T, Fukunaga Y, Niida A, Nagayama S, Mimori K.
    • Journal Title

      Cancer Sci.

      Volume: - Issue: 6 Pages: 1989-2001

    • DOI

      10.1111/cas.16149

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08894, KAKENHI-PROJECT-22K09006, KAKENHI-PROJECT-21K07179, KAKENHI-PROJECT-23K24164
  • [Journal Article] A rare case of liver regenerative and non-neoplastic lesion resembling a well-differentiated hepatocellular carcinoma.2024

    • Author(s)
      Hirose K, Toshima T, Tobo T, Kai S, Hirakawa M, Higuchi S, Ofuchi T, Hosoda K, Yonemura Y, Hisamatsu Y, Masuda T, Aishima S, Mimori K.
    • Journal Title

      Surg Case Rep.

      Volume: 10(1) Issue: 1 Pages: 30-30

    • DOI

      10.1186/s40792-024-01820-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08894, KAKENHI-PROJECT-22K09006, KAKENHI-PROJECT-21K07179, KAKENHI-PROJECT-23K24164
  • [Journal Article] What Are Risk Factors for Graft Loss in Patients Who Underwent Simultaneous Splenectomy During Living-donor Liver Transplantation?2024

    • Author(s)
      Toshima T, Harada N, Itoh S, Tomiyama T, Toshida K, Morita K, Nagao Y, Kurihara T, Tomino T, Kosai-Fujimoto Y, Mimori K, Yoshizumi T.
    • Journal Title

      Transplantation.

      Volume: -

    • DOI

      10.1097/tp.0000000000004952

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K08894, KAKENHI-PROJECT-23K11920
  • [Journal Article] Subclonal accumulation of immune escape mechanisms in microsatellite instability-high colorectal cancers2023

    • Author(s)
      Kobayashi Y, Niida A, Nagayama S, Saeki K, (中略), Mizuno S, Kawazu M, Kohsaka S, Ueno T, Mano H, Ishihara S, Uemura M, Mori M, Doki Y, Eguchi H, Oshima M, Suzuki Y, Shibata T, Mimori K.
    • Journal Title

      Br J Cancer

      Volume: 129 Issue: 7 Pages: 1105-1118

    • DOI

      10.1038/s41416-023-02395-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07153, KAKENHI-PROJECT-21K12117, KAKENHI-PROJECT-22K08894, KAKENHI-PROJECT-22K09006, KAKENHI-PROJECT-23K06662, KAKENHI-PROJECT-23K08128, KAKENHI-PROJECT-21K07179, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-21H02772, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-23K24164
  • [Journal Article] Successful multidisciplinary treatment with complete response to atezolizumab plus bevacizumab in a 90-year-old patient with hepatocellular carcinoma recurrence.2023

    • Author(s)
      Hosoda K, Toshima T, Takahashi J, Yonemura Y, Hisamatsu Y, Hirose K, Masuda T, Motomura Y, Abe T, Ando Y, Dairaku K, Nakano Y, Hashimoto M, Hiraki Y, Soejima Y, Yoshizumi T, Mimori K.
    • Journal Title

      Int Cancer Conf J.

      Volume: 12(4) Issue: 4 Pages: 274-278

    • DOI

      10.1007/s13691-023-00618-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K07774, KAKENHI-PROJECT-22K08826, KAKENHI-PROJECT-22K08894, KAKENHI-PROJECT-23K08215, KAKENHI-PROJECT-21K07179, KAKENHI-PROJECT-23K24164
  • [Journal Article] Spatial and single-cell transcriptomics decipher the cellular environment containing HLA-G+ cancer cells and SPP1+ macrophages in colorectal cancer2023

    • Author(s)
      Ozato Y, Mimori K(28番目),他26名
    • Journal Title

      Cell Reports

      Volume: 42 Issue: 1 Pages: 111929-111929

    • DOI

      10.1016/j.celrep.2022.111929

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08908, KAKENHI-PROJECT-22K19464, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-20H04281, KAKENHI-PROJECT-19K07659, KAKENHI-PROJECT-20K21832, KAKENHI-PUBLICLY-22H04839, KAKENHI-PROJECT-23K24164, KAKENHI-PROJECT-22K08894, KAKENHI-PROJECT-22K09006, KAKENHI-PROJECT-23K06662, KAKENHI-PROJECT-23K08128, KAKENHI-PROJECT-21K07179
  • [Journal Article] PRKRIP1, A Splicing Complex Factor, Is a Marker of Poor Prognosis in Colorectal Cancer.2022

    • Author(s)
      Ozato Y, Masuda T, Kobayashi Y, Takao S, Hisamatu Y, Toshima T, Yonemura Y, Uemura M, Eguchi H, Doki Y, Mori M, Mimori K.
    • Journal Title

      Anticancer Res.

      Volume: 42(10) Issue: 10 Pages: 4701-4706

    • DOI

      10.21873/anticanres.15974

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K07179, KAKENHI-PROJECT-22K08894, KAKENHI-PROJECT-22K09006, KAKENHI-PROJECT-20K09056, KAKENHI-PROJECT-23K24164
  • [Journal Article] Molecular and clinicopathological differences between depressed and protruded T2 colorectal cancer.2022

    • Author(s)
      Mochizuki K, Kudo SE, Kato K, Kudo K, Ogawa Y, Kouyama Y, Takashina Y, Ichimasa K, Tobo T, Toshima T, Hisamatsu Y, Yonemura Y, Masuda T, Miyachi H, Ishida F, Nemoto T, Mimori K.
    • Journal Title

      PLoS One.

      Volume: 17(10) Issue: 10 Pages: 17-17

    • DOI

      10.1371/journal.pone.0273566

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07179, KAKENHI-PROJECT-22K08894, KAKENHI-PROJECT-22K09006, KAKENHI-PROJECT-22K15979, KAKENHI-PROJECT-23K24164
  • [Journal Article] Identification of serum microRNAs as potential diagnostic biomarkers for detecting precancerous lesions of gastric cancer.2022

    • Author(s)
      Otsu H, Nambara S, Hu Q, Hisamatsu Y, Toshima T, Takeishi K, Yonemura Y, Masuda T, Oki E, Mimori K.
    • Journal Title

      Ann Gastroenterol Surg.

      Volume: 7(1) Issue: 1 Pages: 63-70

    • DOI

      10.1002/ags3.12610

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08894, KAKENHI-PROJECT-23K24164
  • [Journal Article] Predictor of outcome after living donor liver transplantation for patients with hepatocellular carcinoma beyond the Japan criteria2020

    • Author(s)
      Yonemura Y, Yoshizumi T, Inokuchi S, Kosai-Fujimoto Y, Harada N, Itoh S, Toshima T, Takeishi K, Yoshiya S, Mori M.
    • Journal Title

      Ann Gastroenterol Surg

      Volume: 4 Issue: 4 Pages: 413-421

    • DOI

      10.1002/ags3.12335

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08542
  • [Journal Article] Impact of Immune Response on Outcomes in Hepatocellular Carcinoma: Association with Vascular Formation2020

    • Author(s)
      Itoh Shinji、Yoshizumi Tomoharu、Yugawa Kyohei、Imai Daisuke、Yoshiya Shohei、Takeishi Kazuki、Toshima Takeo、Harada Noboru、Ikegami Toru、Soejima Yuji、Kohashi Kenichi、Oda Yoshinao、Mori Masaki
    • Journal Title

      Hepatology

      Volume: - Issue: 6 Pages: 1987-1999

    • DOI

      10.1002/hep.31206

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09198, KAKENHI-PROJECT-18K08647
  • [Journal Article] Prognostic Impact of Osteopenia in Patients Who Underwent Living Donor Liver Transplantation for Hepatocellular Carcinoma.2020

    • Author(s)
      Toshima T, Yoshizumi T, Kosai-Fujimoto Y, Inokuchi S, Yoshiya S, Takeishi K, et al.
    • Journal Title

      World J Surg.

      Volume: 44 Issue: 1 Pages: 258-267

    • DOI

      10.1007/s00268-019-05206-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K08542
  • [Journal Article] Lymphocyte-to-Monocyte Ratio Is a Predictor of Survival After Liver Transplantation for Hepatocellular Carcinoma.2018

    • Author(s)
      Mano Y, Yoshizumi T, Yugawa K, Ohira M, Motomura T, Toshima T, Itoh S, Harada N, Ikegami T, Soejima Y, Maehara Y.
    • Journal Title

      Liver Transpl.

      Volume: 24 Issue: 11 Pages: 1603-1611

    • DOI

      10.1002/lt.25204

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K08647
  • [Journal Article] 肝再生とオートファジー2016

    • Author(s)
      戸島剛男、吉住朋晴、森田和豊、内山英昭、本村貴志、伊藤心二、原田昇、播本憲史、池上徹、副島雄二、調憲、前原喜彦
    • Journal Title

      肝胆膵

      Volume: 73 Pages: 1-8

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16K10577
  • [Journal Article] A novel serum marker, glycosylated Wisteria floribunda agglutinin-positive Mac-2 binding protein (WFA+-M2BP), for assessing liver fibrosis.2015

    • Author(s)
      Toshima T, Shirabe K, Ikegami T, et al.
    • Journal Title

      Journal of Gastroenterology

      Volume: 50 Issue: 1 Pages: 76-84

    • DOI

      10.1007/s00535-014-0946-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26861083, KAKENHI-PROJECT-15K10167
  • [Journal Article] Suppression of autophagy during liver regeneration impairs energy charge and hepatocyte senescence in mice.2014

    • Author(s)
      Toshima T1, Shirabe K, Fukuhara T, Ikegami T, Yoshizumi T, Soejima Y, Ikeda T, Okano S, Maehara Y.
    • Journal Title

      Hepatology.

      Volume: 印刷中 Issue: 1 Pages: 25-25

    • DOI

      10.1002/hep.27140

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23591989, KAKENHI-PROJECT-24791433, KAKENHI-PROJECT-26670583, KAKENHI-PROJECT-26861083
  • [Journal Article] Application of Postoperative MELD Scoring System for Evaluating Liver Graft Function After Living Donor Liver Transplantation.2014

    • Author(s)
      Toshima T, Ikegami T, Kimura K, et al.
    • Journal Title

      Transplant Proceedings

      Volume: 46 Issue: 1 Pages: 81-86

    • DOI

      10.1016/j.transproceed.2013.09.034

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26861083
  • [Journal Article] Suppression of autophagy during liver regeneration impairs energy charge and hepatocyte senescence in mice2014

    • Author(s)
      Toshima T, Shirabe K, Fukuhara T, Ikegami T, Yoshizumi T, Soejima Y, Ikeda T, Okano S, Maehara Y
    • Journal Title

      Hepatology

    • Data Source
      KAKENHI-PROJECT-24791433
  • [Journal Article] Autophagy enhances hepatocellular carcinoma progression by activation of mitochondrialβ-oxidation2014

    • Author(s)
      Toshima T, Shirabe K, Matsumoto Y, Yoshiya S, Ikegami T, Yoshizumi T, Soejima Y, Ikeda T, Maehara Y.
    • Journal Title

      J Gastroenterol

      Volume: 49(5) Issue: 5 Pages: 907-16

    • DOI

      10.1007/s00535-013-0835-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23591989, KAKENHI-PROJECT-24592004, KAKENHI-PROJECT-24791433, KAKENHI-PROJECT-26861083
  • [Journal Article] Strategies for successful left-lobe living donor liver transplantation in 250 consecutive adult cases in a single center2013

    • Author(s)
      Ikegami T, Shirabe K, Toshima T, et al.
    • Journal Title

      J Am Coll Surg

      Volume: 216 Pages: 353-62

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791433
  • [Journal Article] Autophagy Enhances Hepatocellular Carcinoma Progression by Activation of Mitochondrial β-oxidation2013

    • Author(s)
      Toshima T, Shirabe K, Yoshiya S, Mano Y, Motomura T, Ikegami, T; Yoshizumi, T; Maehara, Y.
    • Journal Title

      J Gastroenterol

      Volume: (in press)

    • Data Source
      KAKENHI-PROJECT-22659245
  • [Journal Article] A high MELD score, combined with the presence of hepatitis C, is associated with a poor prognosis in living donor liver transplantation2013

    • Author(s)
      Ikegami T, Shirabe K, Toshima T, et al.
    • Journal Title

      Surg Today

      Volume: 23 Pages: 705-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791433
  • [Journal Article] Efficacy of splenectomy in preventing anemia in patients with recurrent hepatitis C following liver transplantation is not dependent on inosine triphosphate pyrophosphatase genotype2012

    • Author(s)
      Motomura T, Koga E, Toshima T, et al.
    • Journal Title

      Hepatol Res

      Volume: 42 Pages: 288-95

    • NAID

      10031144238

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791433
  • [Journal Article] Neutrophil-lymphocyte ratio reflects hepatocellular carcinoma recurrence after liver transplantation via inflammatory microenvironment2012

    • Author(s)
      Motomura T, Shirabe K, Toshima T, et al.
    • Journal Title

      J Hepatol

      Volume: 58 Pages: 58-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791433
  • [Journal Article] One-step reconstruction of the right inferior hepatic veins using auto-venous grafts in living donor liver transplantation2012

    • Author(s)
      Ikegami T, Shirabe K, Toshima T, et al.
    • Journal Title

      Surg Today

      Volume: 18 Pages: 353-62

    • NAID

      10031183388

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791433
  • [Journal Article] The Causes, Risk Factors, and Outcomes of Early Relaparotomy After Living-Donor Liver Transplantation2012

    • Author(s)
      Yoshiya S, Shirabe K, Toshima T, et al.
    • Journal Title

      Transplantation

      Volume: 94 Pages: 947-52

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791433
  • [Journal Article] Diacylglycerol kinase alpha enhances hepatocellular carcinoma progression by activation of Ras-Raf-MEK-ERK pathway2012

    • Author(s)
      Takeishi K, Taketomi A, Toshima T, et al.
    • Journal Title

      J Hepatol

      Volume: 57 Pages: 77-83

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791433
  • [Journal Article] Factors linked to longterm survival of patients with hepatocellular carcinoma accompanied by tumour thrombus in the major portal vein after surgical resection2012

    • Author(s)
      Matono R, Yoshiya S, Toshima T, et al.
    • Journal Title

      HPB (Oxford)

      Volume: 14 Pages: 247-53

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791433
  • [Journal Article] Role of tumor-associated macrophages in the progression of hepatocellular carcinoma2012

    • Author(s)
      Shirabe K, Mano Y, Toshima T, et al.
    • Journal Title

      Surg Today

      Volume: 42 Pages: 1-7

    • NAID

      10030230041

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791433
  • [Journal Article] Poor prognostic factors after repeat hepatectomy for recurrent hepatocellular carcinoma in the modern era2012

    • Author(s)
      Tsujita E, Yamashita Y, Toshima T, et al.
    • Journal Title

      Am Surg

      Volume: 78 Pages: 419-25

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791433
  • [Journal Article] Outcome of hepatectomy for hepatocellular carcinoma in patients with renal dysfunction2012

    • Author(s)
      Toshima T, Shirabe K, Yoshiya S, et al.
    • Journal Title

      HPB (Oxford)

      Volume: 14 Pages: 317-24

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791433
  • [Journal Article] The long-term outcomes of patients with hepatocellular carcinoma after living donor liver transplantation: a comparison of right and left lobe grafts2012

    • Author(s)
      Taketomi A, Shirabe K, Toshima T, et al.
    • Journal Title

      Surg Today

      Volume: 42 Pages: 559-64

    • NAID

      10030622094

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791433
  • [Journal Article] Neither MICA Nor DEPDC5 Genetic Polymorphisms Correlate with Hepatocellular Carcinoma Recurrence following Hepatectomy2012

    • Author(s)
      Motomura T, Ono Y, Toshima T, et al.
    • Journal Title

      HPB Surg

      Volume: 12 Pages: 185496-185496

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791433
  • [Journal Article] En bloc stapling division of the gastroesophageal vessels controlling portal hemodynamic status in living donor liver transplantation2012

    • Author(s)
      Ikegami T, Shirabe K, Toshima T, et al.
    • Journal Title

      J Am Coll Surg

      Volume: 214

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791433
  • [Journal Article] Granulocyte colony-stimulating-factor-producing hepatocellular carcinoma with extensive sarcomatous changes: report of a case2012

    • Author(s)
      Kohno M, Shirabe K, Toshima T, et al.
    • Journal Title

      Surg Today

      Volume: 43 Pages: 439-45

    • NAID

      10031168034

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791433
  • [Journal Article] Total resection of the right hepatic vein drainage area with the aid of three-dimensional computed tomography2012

    • Author(s)
      Taketomi A, Takeishi K, Toshima T, et al.
    • Journal Title

      Surg Today

      Volume: 42 Pages: 46-51

    • NAID

      10030230298

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791433
  • [Journal Article] V5-drainage-preserved right lobe grafts improve graft congestion for living donor liver transplantation2012

    • Author(s)
      Toshima T, Taketomi A, Ikegami T, et al.
    • Journal Title

      Transplantation

      Volume: 93 Pages: 929-35

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791433
  • [Presentation] 肝細胞癌新規ドライバー遺伝子候補Tumor Necrosis Factor Superfamily Member 4(TNFSF4)の同定と臨床的意義2023

    • Author(s)
      巽孝成、増田隆明、本村有史、安東由貴、阿部正、大楽勝司、中野祐輔、橋本雅弘、平木嘉樹、細田清孝 、廣瀬 皓介、米村祐輔、戸島剛男、久松雄一、庄雅之、三森功士
    • Organizer
      第123回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-23K08215
  • [Presentation] 高齢患者に対する生体肝移植術の適応基準と治療成績2023

    • Author(s)
      萱島寛人、原田 昇、戸島 剛、吉屋匠平、長尾吉泰、伊藤心二、吉住朋晴
    • Organizer
      第123回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-23K08174
  • [Presentation] Up-regulated LRRN2 expression as a marker for graft quality in LDLT2023

    • Author(s)
      Tomiyama T, Toshima T, Harada N, Itoh S, Nagao Y, Yoshiya S, Yoshizumi T
    • Organizer
      International Liver Transplantation Society(ILTS) 2023 Annual Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K08174
  • [Presentation] 肝細胞癌新規ドライバー遺伝子Transmembrane Protein 206の同定と作用機序の解明2023

    • Author(s)
      細田 清孝、増田 隆明、斉藤 秀幸、池原 智彦、米村 祐輔、戸島 剛男、久松 雄一、廣瀬 皓介、副島 雄二、三森 功士
    • Organizer
      第78回日本消化器外科学会
    • Data Source
      KAKENHI-PROJECT-23K08215
  • [Presentation] 肝細胞癌染色体コピー数解析による新規ドライバー遺伝子候補Chromosome 1 Open ReadingFrame 112の同定2023

    • Author(s)
      池原 智彦、増田 隆明、細田 清孝、安東 由貴、米村 祐輔、戸島 剛男、久松 雄一、廣瀬 皓介、副島 雄二、三森 功士
    • Organizer
      第78回日本消化器外科学会
    • Data Source
      KAKENHI-PROJECT-23K08215
  • [Presentation] バイオマーカーとなり得る解糖系関連遺伝子の探索2022

    • Author(s)
      斉藤 秀幸, 細田 清孝, 大楽 勝司, 中野 祐輔, 橋本 雅弘, 平木 嘉樹, 阿部 正, 安東 由貴, 本村 有史, 久松 雄一, 戸島 剛男, 米村 祐輔, 増田 隆明, 佐伯 浩司, 三森 功士
    • Organizer
      第42回日本分子腫瘍マーカー研究会
    • Data Source
      KAKENHI-PROJECT-22K08894
  • [Presentation] がんの進展・浸潤に関与する新たな分子生物学的マーカーの開発 エンハンサー活性とDNAコピー数増幅から探る癌進展の新規分子マーカー2022

    • Author(s)
      斉藤 秀幸, 中野 祐輔, 阿部 正, 高橋 純一, 小池 健輔, 酒井 真, 小川 博臣, 宗田 真, 久松 雄一, 戸島 剛男, 米村 祐輔, 増田 隆明, 調 憲, 佐伯 浩司, 三森 功士
    • Organizer
      第60回日本癌治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K08894
  • [Presentation] エンハンサー機能亢進による食道癌の新たながん進展機構2022

    • Author(s)
      斉藤 秀幸, 中野 貴文, 高橋 純一, 久松 雄一, 戸島 剛男, 米村 祐輔, 増田 隆明, 調 憲, 佐伯 浩司, 三森 功士
    • Organizer
      第77回日本消化器外科学会総会
    • Data Source
      KAKENHI-PROJECT-22K08894
  • [Presentation] 網羅的ハブ遺伝子解析に基づく肝細胞癌におけるハブ遺伝子MFSD10発現の臨床的意義2022

    • Author(s)
      高橋 純一, 増田 隆明, 橋本 雅弘, 中野 祐輔, 大楽 勝司, 阿部 正, 斉藤 秀幸, 大里 祐樹, 安東 由貴, 中野 貴文, 久松 雄一, 戸島 剛男, 米村 祐輔, 吉住 朋晴, 三森 功士
    • Organizer
      第112回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-22K08894
  • [Presentation] 大腸癌における新規ドライバー遺伝子候補Zinc finger protein 282(ZNF282)の同定とその臨床学的意義2022

    • Author(s)
      阿部 正(九州大学病院別府病院 外科), 増田 隆明, 細田 清孝, 大樂 勝司, 橋本 雅弘, 中野 祐輔, 平木 嘉樹, 安東 由貴, 本村 有史, 高橋 純一, 久松 雄一, 戸島 剛男, 米村 祐輔, 衛藤 謙, 池上 徹, 三森 功士
    • Organizer
      第81回日本癌学会総会
    • Data Source
      KAKENHI-PROJECT-22K08894
  • [Presentation] 肝細胞癌新規ドライバー遺伝子Tumor Necrosis Factor Superfamily Member 4の同定と作用機序の解明2022

    • Author(s)
      細田 清孝, 増田 隆明, 斉藤 秀幸, 安東 由貴, 阿部 正, 大樂 勝司, 中野 祐輔, 橋本 雅弘, 平木 嘉樹, 米村 祐輔, 戸島 剛男, 久松 雄一, 高橋 純一, 副島 雄二, 三森 功士
    • Organizer
      第81回日本癌学会総会
    • Data Source
      KAKENHI-PROJECT-22K08894
  • [Presentation] HBIGフリーによる生体肝移植後HBV再活性化予防法の成績2020

    • Author(s)
      吉住朋晴、池上 徹、原田 昇、伊藤心二、武石一樹、戸島剛男、吉屋匠平、 森 正樹
    • Organizer
      第56回日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-18K08542
  • [Presentation] 肝癌微小環境における癌関連線維芽細胞由来エクソソームの意義2020

    • Author(s)
      湯川 恭平, 吉住 朋晴, 間野 洋平, 伊勢田 憲史, 冨山 貴央, 森永 哲成, 小斎 侑希子, 井口 詔一, 吉屋 匠平, 武石 一樹, 戸島 剛男, 長尾 吉泰, 伊藤 心二, 原田 昇, 池上 徹, 森 正樹
    • Organizer
      第120回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-18K08647
  • [Presentation] 骨密度低下(オステオペニア)が生体肝移植後の予後に与える影響について2020

    • Author(s)
      戸島 剛男, 吉住 朋晴, 井口 詔1, 小斉 侑希子, 吉屋 匠平, 武石 一樹, 伊藤 心二, 原田 昇, 池上 徹, 森 正樹.
    • Organizer
      第75回日本消化器外科学会総会
    • Data Source
      KAKENHI-PROJECT-18K08647
  • [Presentation] 肝癌増殖におけるオートファジーアダプター蛋白質optineurin発現の意義2020

    • Author(s)
      井口 詔一, 吉住 朋晴, 戸島 剛男, 伊勢田 憲史, 冨山 貴央, 森永 哲成, 湯川 恭平, 小斉 侑希子, 吉屋 匠平, 武石 一樹, 伊藤 心二, 原田 昇, 池上 徹, 森 正樹
    • Organizer
      第120回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-18K08647
  • [Presentation] 酸化ストレス応答因子Nrf2の肝細胞癌における発現の臨床的および生物学的意義2017

    • Author(s)
      下川雅弘、吉住朋晴、伊藤心二、間野洋平、本村貴志、戸島剛男、原田昇、播本憲史、池上徹、副島雄二、前原喜彦
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K10577
  • [Presentation] 肝癌増殖におけるオートファジーの活性化によるエネルギー再構築の重要性2017

    • Author(s)
      戸島剛男、吉住朋晴、副島雄二、池上 徹、播本憲史、原田 昇、 伊藤心二、間野洋平、本村貴志、大平将史、下川雅弘、藤本侑希子、 坂田一仁、井口詔一、川崎淳司、湯川恭平、泉 琢磨、前原喜彦
    • Organizer
      第28回日本消化器癌発生学会総会
    • Data Source
      KAKENHI-PROJECT-16K10577
  • [Presentation] 肝再生におけるオートファジー の生物学的意義2013

    • Author(s)
      戸島剛男
    • Organizer
      日本外科学会定期学術集会
    • Place of Presentation
      福岡
    • Invited
    • Data Source
      KAKENHI-PROJECT-24791433
  • [Presentation] 肝再生における肝再生の意義2013

    • Author(s)
      戸島剛男
    • Organizer
      第113回日本外科学会定期学術集会
    • Place of Presentation
      福岡国際会議場
    • Data Source
      KAKENHI-PROJECT-22659245
  • [Presentation] 肝再生におけるオートファジーの意義2013

    • Author(s)
      戸島剛男、調 憲、吉屋匠平、播本憲史、山下洋市、池上 徹、内山秀昭、吉住朋晴、副島雄二、前原喜彦
    • Organizer
      第113回日本外科学会定期学術集会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-22659245
  • [Presentation] The significance of autophagy in liver regeneration2012

    • Author(s)
      戸島剛男
    • Organizer
      第112回日本外科学会定期学術集会
    • Place of Presentation
      千葉、幕張メッセ
    • Data Source
      KAKENHI-PROJECT-22659245
  • [Presentation] Significance of autophagy in liver regeneration肝再生におけるオートファジーの意義2012

    • Author(s)
      Toshima T.,Shirabe K.,Yoshiya S.,Muto J.,Matono R.,Mano Y.,Morita K.,Kayashima H.,Ikegami T.,Yoshizumi T.,Maehara Y
    • Organizer
      第112回日本外科学会定期学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22659245
  • [Presentation] 肝再生におけるオートファジーの意義2012

    • Author(s)
      戸島剛男
    • Organizer
      第48回日本肝臓学会総会
    • Place of Presentation
      石川
    • Data Source
      KAKENHI-PROJECT-24791433
  • [Presentation] 肝再生におけるオートファジーの生物学的意義2012

    • Author(s)
      戸島剛男、調 憲、吉屋匠平、武藤 純、的野る美、間野洋平、森田和豊、萱島寛人、池上 徹、吉住朋晴、前原喜彦
    • Organizer
      第48回日本肝臓学会総会
    • Place of Presentation
      石川
    • Data Source
      KAKENHI-PROJECT-22659245
  • [Presentation] 肝再生におけるオートファジーの生物学的意義2012

    • Author(s)
      戸島 剛男
    • Organizer
      第48回日本肝臓学会
    • Place of Presentation
      ホテル日航金沢
    • Data Source
      KAKENHI-PROJECT-22659245
  • [Presentation] 肝再生におけるオートファジーの意義2012

    • Author(s)
      戸島剛男
    • Organizer
      第112回日本外科学会定期学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24791433
  • [Presentation] The biological significance of autophagy in hepatocellular carcinoma2011

    • Author(s)
      戸島剛男、調憲
    • Organizer
      The 6^<th> International Society of Gastroenterological carcinogenesis(国際学会)
    • Place of Presentation
      ヒューストン(アメリカ)
    • Year and Date
      2011-01-06
    • Data Source
      KAKENHI-PROJECT-22659245
  • [Presentation] 肝細胞癌におけるオートファジーの意義2011

    • Author(s)
      戸島剛男、調 憲、武冨紹信、福原崇介、吉屋匠平、本村貴志、間野洋平、武藤 純、的野る美、森田和豊、吉住朋晴、池上 徹、前原喜彦
    • Organizer
      第47回日本肝癌研究会
    • Place of Presentation
      静岡
    • Data Source
      KAKENHI-PROJECT-22659245
  • [Presentation] 肝再生におけるオートファジーの意義2011

    • Author(s)
      戸島剛男、調 憲、武冨紹信、本村貴志、間野洋平、武藤 純、的野る美、吉屋匠平、森田和豊、萱島寛人、池上 徹、吉住朋晴、前原喜彦ワークショップ
    • Organizer
      第66回日本消化器外科学会定期学術集会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-22659245
  • [Presentation] The biological significance of autophagy in hepatocellular Carcinoma2011

    • Author(s)
      Toshima T, Shirabe K, Taketomi A, Takeishi K, Yoshimatsu M, Motomura T, Mano Y, Muto J,Ijichi H, Harada N, Uchiyama H, Yoshizumi, T; Maehara, Y.
    • Organizer
      The 6thInternational Society of Gastroenterological Carcinogenesis (ISGC)
    • Place of Presentation
      Kamakura
    • Data Source
      KAKENHI-PROJECT-22659245
  • [Presentation] ワークショップ 演題名:肝再生におけるオートファジーの意義2011

    • Author(s)
      戸島剛男、調 憲、武冨紹信、武石一樹、吉松正憲、本村貴志、間野洋平、武藤 純、的野る美、伊地知秀樹、原田 昇、内山秀昭、吉住朋晴、前原喜彦
    • Organizer
      第111回日本外科学会定期学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22659245
  • [Presentation] 肝細胞癌におけるオートファジーの意義2010

    • Author(s)
      戸島剛男、調憲
    • Organizer
      第48回日本癌治療学会学術集会
    • Place of Presentation
      京都(国立京都国際会館)
    • Year and Date
      2010-10-28
    • Data Source
      KAKENHI-PROJECT-22659245
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    • Author(s)
      戸島剛男、調 憲、武冨紹信、武石一樹、吉松正憲、本村貴志、間野洋平、武藤 純、的野る美、伊地知秀樹、原田 昇、内山秀昭、吉住朋晴、前原喜彦
    • Organizer
      第49回日本癌治療学会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-22659245
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    • Author(s)
      戸島剛男、調憲
    • Organizer
      The 1^<st> JSGE International Topic Conference(国際学会)
    • Place of Presentation
      鎌倉(鎌倉パークホテル)
    • Year and Date
      2010-09-25
    • Data Source
      KAKENHI-PROJECT-22659245
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    • Author(s)
      戸島剛男、調憲
    • Organizer
      第110回日本外科学会 定期学術集会
    • Place of Presentation
      名古屋(名古屋国際会議場)
    • Year and Date
      2010-04-08
    • Data Source
      KAKENHI-PROJECT-22659245
  • [Presentation] 肝再生におけるオートファジーの意義2010

    • Author(s)
      戸島剛男、調憲
    • Organizer
      JDDW2010(日本肝臓学会)
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Year and Date
      2010-10-13
    • Data Source
      KAKENHI-PROJECT-22659245
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    • Author(s)
      戸島剛男、武冨紹信、調 憲、武石一樹、吉松正憲、本村貴志、間野洋平、武藤 純、的野る美、伊地知秀樹、原田 昇、内山秀昭、吉住朋晴、前原喜彦
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-22659245
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    • Author(s)
      戸島剛男
    • Organizer
      平成25年度日本消化器癌発生学会
    • Place of Presentation
      金沢
    • Data Source
      KAKENHI-PROJECT-24791433
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