• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

OBA Toshiharu  大羽 利治

ORCIDConnect your ORCID iD *help
… Alternative Names

大羽 利治  オオバ トシハル

Less
Researcher Number 50008330
Other IDs
Affiliation (based on the past Project Information) *help 2014: 中部大学, 応用生物学部, 教授
2007: Nagoya City University, Graduate School of Medical Sciences, Departments of Cell Physiology, Associate professor
2005 – 2006: 名古屋市立大学, 医学部, 助教授
1996 – 2001: 名古屋市立大学, 医学部, 助教授
1992: 名古屋市立大学, 医学部, 助教授
1988 – 1990: 名古屋市立大学, 医学部, 助教授
Review Section/Research Field
Principal Investigator
General physiology / Neurophysiology and muscle physiology
Except Principal Investigator
General pharmacology / Pediatrics
Keywords
Principal Investigator
筋小胞体 / single channel current / Caチャネル蛋白質 / システイン残基 / SH基 / 活性酸素 / Voltage Sensor / Sulfhydryl Group / Ca Channel Protein / Fluorescence Dye … More / Transverse Tubule / Skeletal Muscle / ETH1001 / Ca電極 / 骨格筋単収縮 / 膜電位 / RH160 / 蛍光強度 / 二重マニト-ル間隙法 / 骨格筋膜電位 / PH160 / 膜電位センサ- / Caチャンネル蛋白質 / シアニン系蛍光色素 / 横行小管 / 骨格筋 / redox potential / cysteine residue / Ryanodine receptor / 酸化還元電位 / チャネル活性 / グルタンチオン / アデニンヌクレオチド / シングルチャネル活性 / 酸化・還元電位 / シングルチャネル電流 / リアノジン受容体 / redox response / cysteineresidue / Ca channel protein / Streptavidin / Ca チャネル / 骨格筋繊維 / ストレプトアビジン / ビオチン / L型Ca^<2+>チャネル / 骨格筋skinned fiber / チャネル修飾剤 / チャネル電流 / 酸化・還元 / 酸化剤 / カタラーゼ / カルシウムチャネル電流 / 筋小胞体カルシウム遊離チャネル / 筋の局所的損傷 / 情報伝達 / SH基の酸化・還元 / Caチャネル / 骨格筋横行小管 … More
Except Principal Investigator
カルシウムイオン / 筋小胞体 / リアノジン受容体 / sarcoplasmic reticulum / calcium ion / ryanodine receptor / heart failure / cardiac hypertrophy / 細胞内Ca2+ / カルモジュリン / 細胞内カルシウム / 心不全 / 心肥大 / Animal model / Action potential / Membrane potential / Skeletal muscle / Myopathy / Creatine kinase / Ionized calcium / Calcium / クレアチンキナーゼ / モデル動物 / 活動電位 / 膜電位 / 骨格筋 / ミオパチー / クレアチン キナーゼ / カルシウム / S4-S5リンカー / 不整脈 / 興奮収縮連関 / 人工アミノ酸 / 相互作用 / カルシウムチャネル Less
  • Research Projects

    (8 results)
  • Research Products

    (8 results)
  • Co-Researchers

    (9 People)
  •  Elucidation of regulatory mechanisms of type 2 ryanodine receptors by introducing artificial amino acids

    • Principal Investigator
      MURAYAMA Takashi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Juntendo University
  •  Molecular mechanisms underlying abnormal functions in RyR2 complex in cardiac hypertrophy/heart failure

    • Principal Investigator
      MURAYAMA Takashi
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Juntendo University
  •  DO CYSTEINES LOCATED NEAR THE CHANNEL PORE OF THE RYANODINE RECEPTOR FUNCTION AS TARGET AMINO ACID FOR REACTIVE OXYGEN SPECIES?Principal Investigator

    • Principal Investigator
      OBA Toshiharu
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      NAGOYA GITY UNIVERSITY
  •  Study on the genetic mechanism underlying "hypocalcemic myopathy" using an animal model

    • Principal Investigator
      ISHIKAWA Tatsuya
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Nagoya City University
  •  CYSTEIN CONFORMATIONAL CHANGES ARE ASSOCIATED WITH INACTIVATION OF L-TYPE CALCIUM CHANNELPrincipal Investigator

    • Principal Investigator
      OBA Toshiharu
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General physiology
    • Research Institution
      Nagoya City University
  •  活性酸素が生理条件下で筋損傷を発現する可能性に関するチャネル分子レベルでの研究Principal Investigator

    • Principal Investigator
      大羽 利治
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Nagoya City University
  •  骨格筋興奮-収縮連関と膜電位センサーの酸化還元反応の関与に関する電気生理学的研究Principal Investigator

    • Principal Investigator
      大羽 利治
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Institution
      Nagoya City University
  •  Coupling of Action Potential of T-Tubule with Ca^<2+> Release form Sarcoplasmic Reticulum in Skeletal MusclePrincipal Investigator

    • Principal Investigator
      OBA Toshiharu
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Neurophysiology and muscle physiology
    • Research Institution
      Nagoya City University

All 2014 2008 2007 2006

All Journal Article Presentation

  • [Journal Article] Multifunctional GFP Tag2014

    • Author(s)
      Murayama T, Kobayashi T
    • Journal Title

      Methods Mol Biol

      Volume: 1177 Pages: 151-161

    • DOI

      10.1007/978-1-4939-1034-2_12

    • ISBN
      9781493910335, 9781493910342
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590330
  • [Journal Article] Cellular redox state protects acetaldehyde-induced alteration in cardiomyocyte function by modifying Ca^<2+> release from sarcoplasmic reticulum2008

    • Author(s)
      Oba, T
    • Journal Title

      Am J Physiol Heart Circ Physiol 294

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590227
  • [Journal Article] Cellular redox state protects acetaldchyde-induced alteration in cardiomyocyte function by modifying Ca2+ release from sarcoplasmic reticulum2008

    • Author(s)
      Oba, Toshiharu
    • Journal Title

      Am.J.Physiol.Heart Circ.Physiol. 294

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590227
  • [Journal Article] Cellular redox state protects acetaldehyde-induced alteration in cardiomyocyte function by modifying Ca2+release from sarcoplasmic reticulum2008

    • Author(s)
      Oba, Toshiharu
    • Journal Title

      Am.J.Physiol.Heart Circ.Physiol. 294

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590227
  • [Presentation] Generation of the GFP-tagged type 1 ryanodine receptor mutants by transposon-based random insertion approach2008

    • Author(s)
      Murayama, T, Kashiyama, T, Oyamada, H, Kobayashi, T, Kurebayashi, N, Sakurai, T
    • Organizer
      Biophysical Society 52nd Annual Meeting
    • Place of Presentation
      Long Beach, CA
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590227
  • [Presentation] 1型リアノジン受容体ドメイン間相互作用により賦活されたチャネル活性に対する酸化の効果2007

    • Author(s)
      大羽 利治
    • Organizer
      第84回日本生理学会大会
    • Place of Presentation
      大阪
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590227
  • [Presentation] Role of a cytoplasmic loop between M7b and M8 transmembrane helices of RyR1 in Ca^<2+> channel gating2007

    • Author(s)
      Murayama, T, Oyamada, H, Oba, T, Oguchi, K, Kurebayashi, N
    • Organizer
      Biophysical Society 51st Annual Meeting
    • Place of Presentation
      Baltimore, MD
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590227
  • [Presentation] Postulated role of interdomain interactions within the type 1 ryanodine receptor in dysfunction of Ca^<2+> release channel in malignant hyperthermia2006

    • Author(s)
      Murayama, T, Oyamada, H, Kurebayashi, N, Oba, T, Hara, H, Wakebe, K, Ikemoto, N, Ogawa, Y
    • Organizer
      Biophysical Society 50th Annual Meeting
    • Place of Presentation
      Salt Laky City, UT
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590227
  • 1.  HOZUMI Tetsh (10080102)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  MURAYAMA Takashi (10230012)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 3.  KUREBAYASHI Nagomi (50133335)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  SAKAMOTO Kensaku (50240685)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  MIURA Yutaka (90285198)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  ISHIKAWA Tatsuya (80080117)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  FUJIMOTO Shinji (60238615)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  中郡 昭人 (50236824)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  国広 なごみ
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi