OHTA Tomihisa 太田富久

Researcher Number	50108560
Other IDs	https://orcid.org/0000-0002-2117-6588
External Links
Affiliation (based on the past Project Information) *help	2012: 金沢大学, 薬学系, 教授 2008 – 2010: Kanazawa University, 薬学系, 教授 2003 – 2004: 金沢大学, 薬学部, 教授 1999 – 2000: 金沢大学, 薬学部, 教授 1994 – 1996: 東北大学, 薬学部, 助教授 … More 1990: 東北大学, 薬学部, 講師 1990: Pharmaceutical Inst., Instructor, Assistant Prof., 薬学部・助手, 講師 1989: 東北大学, 薬学部, 助手 Less
Review Section/Research Field	Principal Investigator 医薬分子機能学 / Chemical pharmacy / Chemical pharmacy Except Principal Investigator Chemical pharmacy / Chemical pharmacy
Keywords	Principal Investigator 担子菌 / scabronine / NGF / diterpenoid / Sarcodon scabrosus / PC-12 / Basidiomycetes / neurotrophic gactor / nerve growth factor / 菌類 … More / アストロサイトーマ / 子嚢菌 / ジテルペノイド / ケロウジ / PC-12細胞 / 神経栄養因子 / 神経成長因子 / Alkaloid / Amino Acid / Phosphodiesterase / Monoamine oxidase / Enzyme inhibition / Mushroom / Brazilian plant / Anti tumor / 天然物 / 微生物 / 植物 / NMR / 生物活性 / 天然資源 / グルタミンデカルボキシラーゼ / 中枢毒性 / 細胞毒性 / アルカロイド / アミノ酸 / ホスホジエステラーゼ / モノアミンオキシダーゼ / 酵素阻害 / ブラジル植物 / 抗腫瘍活性 / スフィンゴ糖脂質 / ペプチドグリカン / 脳症 / スギヒラタケ / 生物活性物質 … More Except Principal Investigator 天然物 / exciton chirality / biaryls / natural products / chiral / method for assignment of absolute configuration / molecular mechanics calculation / asymmetry / circular dichroism / 2級アルコール / アミン / 絶対配置 / 励起子カイラリティー / ビアリール / キラル / 絶対配置決定法 / 分子力場計算 / 不斉 / 円二色性 / ION CHANNEL FORMATION / GP120-CD4 BINDING INHIBITION / MICROTUBULE ASSEMBLY INHIBITION / ANTITUMOR ACTIVITY / IMMUNOSUPPRESSIVE ACTIVITY / BIOFUNCTIONAL CONTROL / MICROORGANISM PRODUCT / DRUG DEVELOPMENTAL RESEARCH / イオン輸送 / 抗微小管活性 / 不完全菌 / 放線菌 / 担子菌 / 子のう菌 / 不斉合成 / イオンチャネル形成機構 / 緑膿菌薬剤耐性阻害活性 / gp120-CD4結合阻害活性 / 微小管機能制御活性 / 微生物由来薬品開発 / 生体機能制御活性 / イオンチャンネル形成 / GP120-CD4結合阻害 / 微小管重合阻害 / 抗腫瘍活性 / 免疫抑制活性 / 生体機能制御 / 微生物生産物 / 医薬品開発研究 / glutamate / calmodulin / 5-lipoxygenase / Basidiomycetes / cytotoxic substances / anti-cancer / 5-リポキシゲネ-ス / グルタミン酸 / カルモジュリン / 5ーリポキシゲネ-ス / 担子菌産物 / 細胞毒性物質 / 抗腫瘍性化合物 / 消化管 / 冬虫夏草属 / アジュバント / 免疫調節 / 蛋白質 / 糖鎖 / 菌類 / 薬学 / ペプチド / 消化管免疫 / 分子構造 / 多糖 / アミノ酸 / 経口免疫 / 免疫アジュバント / 構造 / 糖タンパク / 冬虫夏草 / 人工培養 / 野外採取 / 持続的供給 / 新分子 / 環境保全 / 資源化 / 未利用菌類 Less

Identification of active ingredients of culture fluid from entomogenous fungi that modulate ileal immune responses in murine Peyer's patch cells.
- Principal Investigator
  
  TAKANO Fumihide
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Nihon Pharmaceutical University
  Kanazawa University
Study of encephalopathy inducing constituent in Pleurocybella porrigensPrincipal Investigator
- Principal Investigator
  
  OHTA Tomihisa
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kanazawa University
Development of method for assignment of absolute configuration based on an induced axial chirality and its application to natural products
- Principal Investigator
  
  HOSOI Shinzo
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyushu University of Health and Welfare
未利用菌類の資源化による新分子の発見と環境保全型物質生産
- Principal Investigator
  
  石橋正己
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Chiba University
Investigation of nerve growth factor promotor from fungiPrincipal Investigator
- Principal Investigator
  
  OHTA Tomihisa
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  医薬分子機能学
- Research Institution
  Kanazawa University
DEVELOPMENTAL RESEARCH TO UTILIZE MICROORGANISM PRODUCTS HAVING POTENCY OF BIOFUNCTIONAL CONTROL FOR DRUG MATERIALS
- Principal Investigator
  
  YAMAZAKI Mikio
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Chemical pharmacy
- Research Institution
  CHIBA UNIVERSITY
Investigation of Medicinal Lead Compounds from Natural ResourcePrincipal Investigator
- Principal Investigator
  
  OHTA Tomihisa
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  TOHOKU UNIVERSITY
Isolation of New Medicinal Active Substances from the Source of Mushroom
- Principal Investigator
  
  NOZOE Shigeo
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Tohoku University

All 2012 2011 2010 2009 2008 2004 2001

All Journal Article Presentation Patent

[Journal Article] Anti-inflammatory and Anti-melanogenic Proanthocyanidin Oligomers from Peanut Skin2012
- Author(s)
  T. Tatsuno, M. Jinno, Y. Arima, T. Kawabata, T. Hasegawa, N. Yahagi, F. Takano, T. Ohta
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 35 Issue: 6 Pages: 909-916
- DOI
  10.1248/bpb.35.909
- NAID
  130001872173
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590004
[Journal Article] Garlic extract and its selected organosulphur constituents promote ileal immune responses ex vivo2012
- Author(s)
  N. Ota, F. Takano, S. Muroga, T. Kawabata, Y. Ishigaki, N. Yahagi, T. Ohta
- Journal Title
  
  Journal of Functional Foods
  
  Volume: 4(1) Pages: 243-252
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590004
[Journal Article] Stilbenoids from the melinjo (Gnetum gnemon L.) fruit modulate cytokine production in murine Peyer's patch cells ex vivo2011
- Author(s)
  H. Kato, M. Samizo, R. Kawabata, F. Takano, T. Ohta
- Journal Title
  
  Planta Medica
  
  Volume: 77(10) Issue: 10 Pages: 1027-1034
- DOI
  10.1055/s-0030-1250742
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590004
[Journal Article] Capsicum extract and its constituents modulated the production of immunoglobulins in Peyer's patch cells ex vivo2010
- Author(s)
  M. Yamaguchi, N. Yahagi, H. Kato, F. Takano and T. Ohta
- Journal Title
  
  Journal of Functional Foods
  
  Volume: 2(4) Pages: 255-262
- URL
  http://dx.doi.org/10.1016/j.jff.2010.09.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590004
[Journal Article] Isolation of N-acetyhlneuraminic acid and N-glycolylneuraminic acid from Pleurocybella porrigens2009
- Author(s)
  T.Takata, T.Hasegawa, T.Tatsuno, J.Date, Y.Ishigaki, Y.Nakamura, N.Tomosugid, F.Takano, T.Ohta
- Journal Title
  
  J.Health Science 55(3)
  
  Pages: 373-379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590004
[Journal Article]2009
- Author(s)
  T.Takata, T.Hasegawa, T.Tatsuno, J.Date, Y.Ishigaki, Y.Nakamura, N.Tomosugid, F.Takano, T.Ohta
- Journal Title
  
  J.Health Science 55
  
  Pages: 373-379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590004
[Journal Article] Advanced Method for Assignment of Absolute Configuration Utilizing an Induced CD and Computational Technique : Its Application to Natural Products Possessing a Secondary Alcohol2004
- Author(s)
  S.Hosoi, J.Serata, F.Kiuchi, A.Sakushima, T.Ohta
- Journal Title
  
  Journal of Natural Products 67・9
  
  Pages: 1568-1570
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590004
[Journal Article] Advanced Method for Assignment of Absolute Configuration Utilizing an Induced CD and Computational Technique : Its Application to Natural Products Possessing a Secondary Alcohol2004
- Author(s)
  Shinzo Hosoi, Jun Serata, Fumiyuki Kiuchi, Akiyo Sakushima, Tomihisa Ohta
- Journal Title
  
  Journal of Natural Products 67-9
  
  Pages: 1568-1570
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590004
[Patent] ビアリール型化合物,CD発色剤及び絶対配置決定法2001
- Inventor(s)
  太田富久, 細井信造
- Industrial Property Rights Holder
  金沢大学長
- Patent Publication Number
  2003-002871
- Filing Date
  2001-06-21
- Acquisition Date
  2003-01-08
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590004
[Presentation] N-glycoryl neuraminic acid from edible/toxic mushroom pleurocy bella porrigens2008
- Author(s)
  J. Date, T. Takata, T. Tatsuno, Y. Ishigaki. F. Takano, T. Ohta
- Organizer
  The 4^<th> KSP-JSP-CCTNM Joint Symposium on Pharmacognosy, 2008
- Place of Presentation
  Gangneung, Korea
- Year and Date
  2008-06-18
- Data Source
  KAKENHI-PROJECT-20590004
[Presentation] N-glycoryl neuraminic acid from edible/toxic mushroom Pleurocybella porrigens2008
- Author(s)
  J.Date, T.Takata, T.Tatsuno, Y.Ishigaki, F.Takano, T.Ohta
- Organizer
  The 4^<th> ASP-JSP-CCTNM Joint Symposium on Pharmacognosy
- Place of Presentation
  KAIST(Kore)
- Year and Date
  2008-06-18
- Data Source
  KAKENHI-PROJECT-20590004

1. NOZOE Shigeo (50013305)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. TAKANO Fumihide (20236251)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. ISHIGAKI Yasuhito (20232275)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. TAKAHASHI Akira (00216699)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. FUSHIYA Shinji (80108563)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KUSANO Genjiro (90004598)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KONDO Yoshikazu (30004584)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. YAMAZAKI Mikio (70089598)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. NAGAO Yoshimitsu (40027074)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. NAKAGAWA Akira (60050548)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TANAKA Haruo (40118823)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. IWASAKI Shigeo (00013326)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. HOSOI Shinzo (60209236)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. SAKUSHIMA Akiyo (40094833)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. KIUCHI Fumiyuki (60161402)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. 石橋正己 (90212927)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 小鹿一 (50152492)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 大島吉輝 (00111302)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 飯田彰 (40202816)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 貫名学 (20113970)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 浪越通夫 (30189196)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. YAHAGI Nobuo

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

OHTA Tomihisa 太田 富久

Research Projects

Research Products

Co-Researchers

Identification of active ingredients of culture fluid from entomogenous fungi that modulate ileal immune responses in murine Peyer's patch cells.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of encephalopathy inducing constituent in Pleurocybella porrigensPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of method for assignment of absolute configuration based on an induced axial chirality and its application to natural products

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

未利用菌類の資源化による新分子の発見と環境保全型物質生産

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of nerve growth factor promotor from fungiPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

DEVELOPMENTAL RESEARCH TO UTILIZE MICROORGANISM PRODUCTS HAVING POTENCY OF BIOFUNCTIONAL CONTROL FOR DRUG MATERIALS

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of Medicinal Lead Compounds from Natural ResourcePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Isolation of New Medicinal Active Substances from the Source of Mushroom

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Anti-inflammatory and Anti-melanogenic Proanthocyanidin Oligomers from Peanut Skin2012

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Garlic extract and its selected organosulphur constituents promote ileal immune responses ex vivo2012

Author(s)

Journal Title

Data Source

[Journal Article] Stilbenoids from the melinjo (Gnetum gnemon L.) fruit modulate cytokine production in murine Peyer's patch cells ex vivo2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Capsicum extract and its constituents modulated the production of immunoglobulins in Peyer's patch cells ex vivo2010

Author(s)

Journal Title

URL

Data Source

[Journal Article] Isolation of N-acetyhlneuraminic acid and N-glycolylneuraminic acid from Pleurocybella porrigens2009

Author(s)

Journal Title

Data Source

[Journal Article]2009

Author(s)

OHTA Tomihisa 太田富久