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YAMAZAKI Mikio  山崎 幹夫

ORCIDConnect your ORCID iD *help
Researcher Number 70089598
External Links
Affiliation (based on the past Project Information) *help 1987 – 1996: Faculty of Pharmaceutical Sciences, Chiba University, 薬学部, 教授
1986: 千葉大, 生物活性研究所, 教授
1986: 千葉大学, 生物活性研究所, 教授
Review Section/Research Field
Principal Investigator
Chemical pharmacy
Except Principal Investigator
Chemical pharmacy / Biological pharmacy
Keywords
Principal Investigator
フミトレモルジンA / 向神経性化合物 / てんかんモデル / 【^3H】-グルタミン酸結合能 / ^3H-グルタミン酸結合能 / ジヒドロフミトレモルジンC / 向神経医薬品素材 / 鎮静効果 / 伝承薬 / 向神経活性 … More / 和漢薬 / 東南アジアの生薬 / ペルー生薬 / ボルネオ生薬 / Neurotropic Drug-Source / Sedation / Traditional Medicine / Neurotropic Effect / Japanese-Chinese Drug / South-Asian Drug / Peruvian Herbal Medicine / 医薬品開発研究 / 微生物生産物 / 生体機能制御 / 免疫抑制活性 / 抗腫瘍活性 / 微小管重合阻害 / GP120-CD4結合阻害 / イオンチャンネル形成 / 生体機能制御活性 / 微生物由来薬品開発 / 微小管機能制御活性 / gp120-CD4結合阻害活性 / 緑膿菌薬剤耐性阻害活性 / イオンチャネル形成機構 / 不斉合成 / 子のう菌 / 担子菌 / 放線菌 / 不完全菌 / 抗微小管活性 / イオン輸送 / DRUG DEVELOPMENTAL RESEARCH / MICROORGANISM PRODUCT / BIOFUNCTIONAL CONTROL / IMMUNOSUPPRESSIVE ACTIVITY / ANTITUMOR ACTIVITY / MICROTUBULE ASSEMBLY INHIBITION / GP120-CD4 BINDING INHIBITION / ION CHANNEL FORMATION / フミトレモルジンA、B関連誘導体 / 興奮性アミノ酸受容体 / てんかん類似症状 / フミトレモルジンC / フミトレモルジンA類似化合物 / フミトレモルジンA,B関連誘導体 / epilepsy model / convulsant / fungal metabolite … More
Except Principal Investigator
化学合成 / 脳機能改善薬 / グルタミン酸受容体 / 海洋生物 / 海洋天然物質 / 生物活性物質 / 海洋医薬素材 / 海洋リ-ド化合物 / トキシコロジ- / ファ-マコロジ- / 生物トキシン / トキシンの産生と制御 / トキシンの化学構造と活性部位 / トキシンの細胞受容体 / 生体機能解析 / 新薬開発 / 天然資源 / 合成医薬品 / 薬効評価 / 薬効発現機構 / 薬物の安全性 / 薬学教育 / 天然薬用資源 / 薬理学的研究 / 体内動態 / 安全性 / new drug development / natural resources / synthetic drug / pharmaceutical / evaluation / mechanism of drug action / drug safety / pharmacy education / βーカルボリン / スフィンゴ脂質 / ユ-ディストミン / 向中枢神経作用物質 / モノアミン酸化酵素 / 子嚢菌 / 胃液分泌中枢性調節 / β-カルボリン / 胃液分泌の中枢性調節 / Cerebral Insufficiency Improving Activity / beta-Carbolines / Eudistomins / Manzamine C / Central Nervous System / Monoamine Oxidase Inhibitors / Gastric Acid Secretion / Fungi / 熱帯薬用植物 / 医薬品開発 / 薬用植物成分 / 薬理作用 / 生理活性物質 / 抗微生物活性 / 医薬品製剤 / アルカロイド / 医薬品開発の基礎研究 / 有効成分の分離方法 / 薬用植物成分の化学構造 / 生物活性物質の探索 / Tropical and medical plants / Development of medicines / Compounds of medical plants / Pharmacological effect / Biological active substance / Antimicrobial activity / Pharmaceuticals / Alkaloid / 医薬資源 / 微生物代謝物 / 生理活性 / 天然資源からの検索 / 活性誘導体 / 生物活性 / 作用機構 / 生合成 / Medicinal Resources / Microbial Products / Bioactivity / Natural Sources / Synthetic Supply / 不斉Pictet-Spengler反応 / 向神経性菌類代謝産物 / 向神経性生薬成分 / GABA受容体 / オピオイド受容体 / 1-置換-テトラヒドロ-β-カルボリン / 不斉Picter-Spengler反応 / 酢酸ライジング抑制活性成分 / 鎮痛作用 / 身体依存性 / MAO阻害活性成分 / インドールアルカロイド / β-カルボリン系菌類代謝産物 / 不斉Pictet-spengler反応 / 向神経性伝承薬 / NO / mitragynine / ニューロステロイド / 痙攣性菌類代謝産物 / 八方向放射状迷路 / グルタミン酸作動性神経 / GABA作動性神経 / 向精神性伝承薬 / 抗痴呆薬 / Asymmetric Pictet-Spengler Reaction / 1-Substituted Tetrahydro-beta-carbolines / Neurotropic Fungal Metabolites / Neurotropic Crude Drug Components / GABA receptor / Glutamate receptor / Opioid receptor / Nootropic Drug / 向真核細胞活性 / 微生物代謝産物 / 向神経性 / 血小板凝集抑制 / 抗腫瘍性 / 抗カビ性 / アクチン / 微小管タンパク活性阻害 / 向真経性 / Effect on eucaryotic cells / microbial products / neurotropic / peletelet aggregation inhibition / antitumor / antifungal Less
  • Research Projects

    (13 results)
  • Co-Researchers

    (101 People)
  •  Studies on the beta-Carboline Derivatives as Lead Compounds of Therapeutics for Brain-Gut and Central Nervous Diseases

    • Principal Investigator
      WATANABE Kazuo
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      Chiba University
  •  DEVELOPMENTAL RESEARCH TO UTILIZE MICROORGANISM PRODUCTS HAVING POTENCY OF BIOFUNCTIONAL CONTROL FOR DRUG MATERIALSPrincipal Investigator

    • Principal Investigator
      YAMAZAKI Mikio
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Chemical pharmacy
    • Research Institution
      CHIBA UNIVERSITY
  •  Basic study on development of medicines from tropical plants

    • Principal Investigator
      HIROSE Seiyu
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Chiba University
  •  STUDY ON THE MICROBIAL METABOLITRES AS THE MEDICINAL RESOURCES

    • Principal Investigator
      IWASAKI Shigeo
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Chemical pharmacy
    • Research Institution
      THE UNIVERSITY OF TOKYO
  •  BASIC STUDY ON TRADITIONAL MEDICINES HAVING SEDATIVE EFFECT FOR SEARCH OF NEUROTROPIC DRUG-MATERIALPrincipal Investigator

    • Principal Investigator
      YAMAZAKI Mikio
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Chemical pharmacy
    • Research Institution
      CHIBA UNIVERSITY
  •  海洋生物由来の新しい医薬素材の開発

    • Principal Investigator
      北川 勲
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Osaka University
  •  General Studies on the Development of Novel Materials and their Evaluation as new Drugs

    • Principal Investigator
      SUZUKI Tokuji
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Chiba University
  •  Survey Investigation of Lead Compounds Towards Cerebral Insufficiency Improving Activity

    • Principal Investigator
      HINO Tohru
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      Chemical pharmacy
    • Research Institution
      Chiba University
  •  化学的刺激てんかんモデルとして有用な神経伝達物質受容体への作用物質の開発Principal Investigator

    • Principal Investigator
      山崎 幹夫
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Chiba University
  •  化学的刺激てんかんモデルとして有用な神経伝達物質物質受容体への作用物質の開発Principal Investigator

    • Principal Investigator
      山崎 幹夫
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Chiba University
  •  Research and development of common model of epilepsy with fumitremorgin-like central nervous stimulative compounds.Principal Investigator

    • Principal Investigator
      YAMAZAKI Mikio
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      Chemical pharmacy
    • Research Institution
      Faculty of Pharmaceutical Sciences, Chiba University
  •  Studies on Macrobial Metabolites Effective to Eucaryotic Cells

    • Principal Investigator
      IWASAKI Shigeo, 奥田 重信
    • Project Period (FY)
      1985 – 1987
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Chemical pharmacy
    • Research Institution
      The University of Tokyo
  •  「生物トキシンの基礎的研究とその医学生物学への応用」研究成果のとりまとめ

    • Principal Investigator
      加藤 巌
    • Project Period (FY)
      1983 – 1986
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Chiba University
  • 1.  HINO Toru (10009160)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 2.  WATANABE Kazuo (80019124)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  NAKAGAWA Masao (40009171)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  SUZUKI Shigetoshi (90092064)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  IWASAKI Shigeo (00013326)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  NOZOE Shigeo (50013305)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  JAMARI F.
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  KNAUS
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  FRIESEN
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 10.  NOUJAIM
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 11.  LOCOCK
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 12.  TAM
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 13.  PASUTTO
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 14.  BIGGS
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 15.  MICETICH
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 16.  WIEBE
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 17.  WOLOWYK
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 18.  SAWAI Testuo (70009174)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 19.  FUJITA Tetsuro (40027024)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 20.  SATO Testuo (60092061)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 21.  HIROSE Seiyu (40009163)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 22.  ISHII Hisashi (70009166)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 23.  SAKAI Shin-ichiro (20009161)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 24.  MURAKOSHI Isamu (30009162)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 25.  COUTTS
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 26.  MOSKALYK
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 27.  SUZUKI Tokuji (40010219)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  UNEMOTO Tsutomu (30089601)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  IMANARI Toshio (20012619)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  IGARASHI Kazuei (60089597)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  ISHII Itsuko (00202929)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  YAMAGUCHI Akihito (60114336)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  YAMAMOTO Keiji (50110341)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  OKUYAMA Emi (50204152)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  FUJIMOTO Haruhiro (50089603)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  NAGAO Yoshimitsu (40027074)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  NAKAGAWA Akira (60050548)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  TANAKA Haruo (40118823)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  OHTA Tomihisa (50108560)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  YANO Shingo (90009655)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  NAKAMURA Shoshiro (40013304)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 42.  MIKAMI Yuzuru (40092100)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 43.  北川 勲 (20028830)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 44.  伏谷 伸宏 (70012010)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 45.  高野 誠一 (20004559)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 46.  安元 健 (20011885)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 47.  柿澤 寛 (50015492)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 48.  加藤 巌 (40012702)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 49.  内田 驍 (40029781)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 50.  三論谷 俊夫 (60029759)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 51.  竹田 美文 (30029772)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 52.  新井 正 (30009419)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 53.  山根 靖弘 (40009155)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 54.  仲井 由宣 (80009159)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 55.  細谷 東一郎 (10019648)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 56.  佐藤 良博 (20050726)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 57.  奥田 重信 (30013296)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 58.  ATMIYANAN Preeya
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 59.  PONGLUX Dhavadee
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 60.  BIGGS D. F.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 61.  KNAUS E. E.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 62.  LOCOCK R. A.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 63.  PASUTTO F. M.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 64.  FRIESEN A. J. D.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 65.  COUTTS R. T.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 66.  TAM Y. K.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 67.  NOUJAIM A. A.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 68.  WOLOWYK M. W.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 69.  MICETICH R. G.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 70.  MOSKALYK R. E.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 71.  WIEBE L. I.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 72.  COUTIS
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 73.  BAVOVADA Rap
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 74.  SAIFAH Ekari
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 75.  KULVANICH Po
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 76.  NIMMANNIT Ub
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 77.  TANTISIRA Ma
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 78.  TONGROACH Pa
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 79.  PUMMANGURA S
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 80.  LIPIPAN Vimo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 81.  PRAMYOTHIN P
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 82.  PORNPEN Pramyothin
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 83.  RAPEPOL Bavovada
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 84.  UBONTHIP Nimmannit
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 85.  VIMOLMAS Lipipan
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 86.  EKARIN Saifah
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 87.  PUMMANGURA Sunibhond
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 88.  TANTISIRA Mayuree H.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 89.  PAVICHI Tongroach
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 90.  POJ Kulvanich
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 91.  U Nimmannit
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 92.  R Bavovada
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 93.  P Tongroach
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 94.  P Kulvanich
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 95.  M Tantisira
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 96.  S Pummangura
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 97.  P Atmiyanan
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 98.  D Pouglux
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 99.  SAISORN B.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 100.  POUGLUX D.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 101.  TANTISIRA M.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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