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SAKAI Shin-ichiro  坂井 進一郎

ORCIDConnect your ORCID iD *help
Researcher Number 20009161
External Links
Affiliation (based on the past Project Information) *help 1998: 千葉大学, 薬学部, 名誉教授
1995 – 1996: Chiba University Emenritus Professor, 名誉教授
1986 – 1994: 千葉大学, 薬学部, 教授
1986: 千葉大, 薬学部, 教授
Review Section/Research Field
Principal Investigator
Chemical pharmacy
Except Principal Investigator
Bioorganic chemistry / Chemical pharmacy
Keywords
Principal Investigator
インド-ルアルカロイド / 構造決定 / Raumaclines / Aspidosperma quebracho blanco / 化学変換 / Indole Alkaloids / Mitragyna speciosa / インドールアルカロイド / 植物組織培養 / Rauwolfia serpentina … More / 生物変換 / Aspidochibine / Raumacline / アジマリン / Aspidasperma queblacho blanco / Aspidosperma gmbir / Plant Tissue Cultures / Structure Elucidation / Rauwolfia serpentina Benth / Biotransformation of ajmaline / Aspidochibine. / ゲルセミウム / 生合成的化学合成 / 生合成模擬反応 / 化学変換反応 / Gelsemium / Biomimetic Synthesis / タイ薬用植物 / Mitragynine / 鎮痛活性 / セロトニン受容体 / オピオイド受容体 / Caチャンネル / 平滑筋収縮作用 / アルカロイド化学合成 / オピオイド作用 / Hunteria zeylanica / Rauwolfia sumatorana / アルカロイドの化学合成 / Thai medicinal plant / indole alkaloid / mitragynine / analgesic effect / serotonin receptor / opioid receptor / Ca channel / タイ / 薬用植物 / キョウチクトウ科 / アカネ科 / マチン科 / キク科 / 配糖体 / 弥用植物 / オキシインドールアルカロイド / タイ産薬用植物 / アルカロイド / 生合成機構 / Thailand / Medicinal plant / Apocynaceae / Rubiaceae / Loganiaceae / Compositae / Indole alkaloid … More
Except Principal Investigator
アルカロイド / インドールアルカロイド / HHPA / 発がん / 発がんプロモーター / テレオシジン / フォルボール / 構造活性相関 / インドラクタム / レチノイン酸 / オカダ酸 / オレアノール酸 / 発がん阻害物質 / Okadaic acid / phorbol esterレセプター / Teleocidin / TPA / aplysiatpxin / 発癌プロモーターprotein Kinase C / okadaic acid / dinophysistoxin-1(35-methylokadaic acid) / C-H-ras / (-)indolactam-V / LM-5、LM-6 / protein kinase C / 新薬開発 / 天然資源 / 合成医薬品 / 薬効評価 / 薬効発現機構 / 薬物の安全性 / 薬学教育 / 天然薬用資源 / 薬理学的研究 / 体内動態 / 安全性 / new drug development / natural resources / synthetic drug / pharmaceutical / evaluation / mechanism of drug action / drug safety / pharmacy education / 熱帯薬用植物 / 医薬品開発 / 薬用植物成分 / 薬理作用 / 生理活性物質 / 抗微生物活性 / 医薬品製剤 / 医薬品開発の基礎研究 / 有効成分の分離方法 / 薬用植物成分の化学構造 / 生物活性物質の探索 / Tropical and medical plants / Development of medicines / Compounds of medical plants / Pharmacological effect / Biological active substance / Antimicrobial activity / Pharmaceuticals / Alkaloid / 植物細胞培養 / 細胞融合 / 再分化 / キョウチクトウ科 / アカネ科 / アントラキノン / 二次代謝 / 融合細胞 / Rauwolfia serpentina / Rhazya stricta / Ophiorrhiza spp. / Plant cell culture / Cell fusion / Differentiation / Apocynaceae / Rubiaceae / Indole alkaloid / Anthraquinone / Secondary metabolism / タイ伝承民間薬 / 鎮痛性植物塩基 / ミトラガイナ属アルカロイド / アルカロイドの化学合成 / アルカロイドの化学変換 / ミトラガイナ属植物 / アルカロイド合成 / 化学変換反応 / インドールアルカロイドの化学構造 / インドールアルカロイドの合成 / Thai Traditional Medicine / Analgesic Alkaloid / Mitragyna speciosa / Chemical Constituent / Indole Alaloid / Mitragynine / Chemical Synthesis / ミトラガイナ スペシオーサ / インドール / イソキノリン / 海洋天然物 / 構造決定 / 全合成 / オピオイド / 抗腫瘍活性 / ミトラガイニン / オピオイド受容体 / 化学合成 / Mitragyna spociosa / indole / isoquinoline / marine natural product / structure elucidation / total synthesis / opioid / antitumor activity / 番傘村 / 皮膚がん / 発がんプロモ-タ- / Umbrella Village / Skin Cancer / Tumor Promoter Less
  • Research Projects

    (14 results)
  • Co-Researchers

    (120 People)
  •  Medicinal Chemistry on Alkaloids from Plants in Malaya Area

    • Principal Investigator
      KUBO Akinori
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A).
    • Research Field
      Chemical pharmacy
    • Research Institution
      MEIJI PHARMACEUTICAL UNIVERSITY
  •  Medicinal Chemistry on Indole Alkaloids from Thai Medicinal PlantsPrincipal Investigator

    • Principal Investigator
      SAKAI Shin-ichiro
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Chiba University
  •  Investigation and synthetic studies of bioactive Mitragyna alkaloids.

    • Principal Investigator
      TAKAYAMA Hiromitsu
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Bioorganic chemistry
    • Research Institution
      Chiba University
  •  Basic study on development of medicines from tropical plants

    • Principal Investigator
      HIROSE Seiyu
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Chiba University
  •  Formation of Alkaloid's by Function of Cultured Plant Cells

    • Principal Investigator
      AIMI Norio
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Chiba University
  •  Chemical Study on the Indole Alkaloids from Plant Tissue CulturesPrincipal Investigator

    • Principal Investigator
      SAKAI Shin-ichiro
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Chiba University
  •  General Studies on the Development of Novel Materials and their Evaluation as new Drugs

    • Principal Investigator
      SUZUKI Tokuji
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Chiba University
  •  Synthetic Studies on the Gelsemium Alkaloids Based on the Biogenetic SpeculationPrincipal Investigator

    • Principal Investigator
      SAKAI Shin-ichiro
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Chiba University
  •  新しい発癌プロモーター及び抑制物質の探索とその特性に関する研究

    • Principal Investigator
      FUJIKI Hirota
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  新しい発癌プロモーター及び抑制物質の探索とその特性に関する研究

    • Principal Investigator
      藤木 博太
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  タイ国の環境発癌プロモーターと人癌との関係

    • Principal Investigator
      藤木 博太
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Overseas Scientific Research
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  Human skin cancer in relation to environmental tumor promoters in Thailand

    • Principal Investigator
      FUJIKI Hirota
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for Overseas Scientific Survey.
    • Research Institution
      National Cancer Center Research Institute
  •  発がんプロモーターの構造と有機化学研究

    • Principal Investigator
      首藤 紘一
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  Studies on the constituents of Thai medicinal plantsPrincipal Investigator

    • Principal Investigator
      SAKAI Shin-ichiro
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Chiba University
  • 1.  TAKAYAMA Hiromitsu (90171561)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 2.  AIMI Norio (30009170)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 3.  FUJIKI Hirota (60124426)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  PONGLUX Dhavadee
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  WATANABE Kazuo (80019124)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  KITAJIMA Mariko (60195261)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  首藤 紘一 (50012612)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  小清水 弘一 (90026518)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  JAMARI F.
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 10.  KNAUS
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 11.  FRIESEN
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 12.  NOUJAIM
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 13.  LOCOCK
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 14.  TAM
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 15.  PASUTTO
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 16.  BIGGS
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 17.  MICETICH
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 18.  WIEBE
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 19.  WOLOWYK
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 20.  SAWAI Testuo (70009174)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 21.  SATO Testuo (60092061)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 22.  HIROSE Seiyu (40009163)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 23.  YAMAZAKI Mikio (70089598)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 24.  ISHII Hisashi (70009166)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 25.  HINO Toru (10009160)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 26.  MURAKOSHI Isamu (30009162)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 27.  MIKI Yoshiharu (30028336)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 28.  MATSUSHIMA Taijiro (10012759)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 29.  平田 義正 (10022493)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 30.  武藤 泰敏 (20010069)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 31.  STOCKIGT Joachim
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 32.  PONGLUX D.
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 33.  STOCKIGT J.
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 34.  COUTTS
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 35.  MOSKALYK
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 36.  DHAVADEE Pon
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 37.  SUZUKI Tokuji (40010219)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  UNEMOTO Tsutomu (30089601)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  IMANARI Toshio (20012619)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  IGARASHI Kazuei (60089597)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  ISHII Itsuko (00202929)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 42.  YAMAGUCHI Akihito (60114336)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 43.  YAMAMOTO Keiji (50110341)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 44.  HORIE Shunji (50209285)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 45.  YANO Shingo (90009655)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 46.  WATANABE Hiroshi (10012642)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 47.  KUBO Akinori (60097201)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 48.  SAITO Naoki (80142545)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 49.  太田 敏晴 (50114418)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 50.  板井 昭子 (60012647)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 51.  上村 大輔 (00022731)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 52.  山根 靖弘 (40009155)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 53.  仲井 由宣 (80009159)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 54.  細谷 東一郎 (10019648)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 55.  池上 文雄 (90159608)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 56.  ATMIYANAN Preeya
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 57.  OBITZ Peter
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 58.  TONGROCH Pavich
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 59.  SUTTAJIT Maitree
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 60.  WONGCHAI Vichai
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 61.  ZENK M.H.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 62.  STOECKIGT Joachim
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 63.  ZENK Meinhart H.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 64.  ZENK M.K.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 65.  BIGGS D. F.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 66.  KNAUS E. E.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 67.  LOCOCK R. A.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 68.  PASUTTO F. M.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 69.  FRIESEN A. J. D.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 70.  COUTTS R. T.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 71.  TAM Y. K.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 72.  NOUJAIM A. A.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 73.  WOLOWYK M. W.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 74.  MICETICH R. G.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 75.  MOSKALYK R. E.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 76.  WIEBE L. I.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 77.  COUTIS
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 78.  BAVOVADA Rap
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 79.  SAIFAH Ekari
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 80.  KULVANICH Po
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 81.  NIMMANNIT Ub
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 82.  TANTISIRA Ma
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 83.  TONGROACH Pa
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 84.  PUMMANGURA S
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 85.  LIPIPAN Vimo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 86.  PRAMYOTHIN P
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 87.  PORNPEN Pramyothin
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 88.  RAPEPOL Bavovada
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 89.  UBONTHIP Nimmannit
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 90.  VIMOLMAS Lipipan
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 91.  EKARIN Saifah
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 92.  PUMMANGURA Sunibhond
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 93.  TANTISIRA Mayuree H.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 94.  PAVICHI Tongroach
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 95.  POJ Kulvanich
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 96.  U Nimmannit
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 97.  R Bavovada
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 98.  P Tongroach
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 99.  P Kulvanich
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 100.  M Tantisira
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 101.  S Pummangura
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 102.  P Atmiyanan
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 103.  D Pouglux
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 104.  SAISORN B.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 105.  POUGLUX D.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 106.  TANTISIRA M.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 107.  CARL M Ruyte
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 108.  JOACHIM Stoe
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 109.  PANG Peter K
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 110.  KTPANG Peter
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 111.  JOACHIM Stoc
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 112.  PAVICH Tongr
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 113.  JOACHIM Sto
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 114.  PETER KT Pa
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 115.  DHAVADEE Po
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 116.  PAVICH Tong
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 117.  PETER KT Pan
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 118.  竹宮 聖隆
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 119.  白石 稔
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 120.  廣田 満
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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