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ITAI AKIKO
板井 昭子
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Alternative Names
板井 昭子 イタイ アキコ
ITAI Akiko 板井 昭子
坂井 昭子 イタイ アキコ
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Researcher Number
60012647
External Links
Affiliation (Current)
2022: 株式会社医薬分子設計研究所, その他部局等, その他
Affiliation (based on the past Project Information)
*help
2014 – 2016: 株式会社医薬分子設計研究所, その他部局等, その他
1996 – 1999: 北里研究所, 部長研究員
1995: (社)北里研究所, 生物機能研究所, 部長研究員
1995: The Kitasato Institute, Center for Biological Function, Senior Research Scientist, 生物機能研究所, 部長研究員
1994: 東京大学, 薬学部, 客員教授
…
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1994: 東京大学, 薬学部, 教授
1993: 東京大学, 薬学部, 助教授
1990 – 1993: 東京大学, 薬学部, 客員助教授
1990 – 1991: Univ. Tokyo, Fac. Pharm. Sci., Assoc. Prof., 薬学部, 助教授
1986 – 1989: 東京大学, 薬学部, 助手
1986: 東大, 薬学部, 助手
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Review Section/Research Field
Principal Investigator
Chemical pharmacy
/
Physical pharmacy
/
医薬分子機能学
Except Principal Investigator
広領域
/
医薬分子機能学
/
Morphological basic dentistry
/
寄生虫学(含医用動物学)
/
Physical pharmacy
Keywords
Principal Investigator
酵素阻害剤 / コンピュータ薬物設計 / 分子設計 / 構造活性相関 / リ-ド創製 / ジヒドロ葉酸還元酵素 / computer drug design / コンピュータ・グラフィックス / コンピュ-タ・プログラム / コンピュータ分子設計
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More
/ 薬物一受容体相互作用 / マラリア / ドラッグデザイン / ドッキング・スタディ / 分子重ね合わせ / lead generation / コンピュータ / 発がんプロモーター / 薬物ー受容体相互作用 / リード創製 / マラリア治療薬 / 蛋白質モデリング / デノボリガンド設計 / ドッキングスタデイ / コンピュータ・プログラム / コンピュータ・シミュレーション / 生理活性化合物 / 薬物-受容体相互作用 / コンピュ-タ / 薬物設計 / 分子間相互作用 / 受容体-薬物相互作用 / コンピュ-タ・ソフトウェア / protein structure / drug-receptor interaction / dihydrofolate reductase / morphine / 医薬リ-ド / リガンド設計 / 3次元構造データベース / 自動ドッキング / 自動構築法 / 3次元データベース / 受容体の立体構造 / drug design / drug lead / drug design software / de novo ligand design / ソフトウェア / コンピュータ・グラフィックスソフトウェア / ソフトウェア開発 / structure-activity relationaships / computer graphics / softwares / molecular superposition
…
More
Except Principal Investigator
ブレオマイシン / DNA切断 / 酸素活性化 / コレシストキニン / ドラッグデザイン / 受容体 / 構造活性相関 / 予測高次構造 / HBcAg dimer / HBsAg inner dimer / B型肝炎ウィルス / アミノ酸配列 / 熱帯熱マラリア / P.falciparum / 3SPACE digitizer / エスペラミシン / T細胞 / シアロシルグリセロリピド / ジメチルホスフィニル基 / 癌細胞障害性マクロファ-ジ / レクチン / 0ージメチルホスフィニル基 / 複合系の分子機能 / アルツハイマ-型痴呆 / 抗生物質 / インタ-カレ-ション / 癌細胞認識分子 / 医薬創製 / 受容体リガンド / 口腔扁平上皮癌 / NF-κB / IκBキナーゼβ / IMD-056 / NF-kB / IkBキナーゼb / IMD-0560 / IkBキナーゼβ / 発がん / 発がんプロモーター / テレオシジン / フォルボール / インドラクタム / レチノイン酸 / オカダ酸 / オレアノール酸 / 発がん阻害物質 / 正二十面体 / 糖鎖 / ジアシル型フオスフアチジルコリン / 分子充填モデル / 峡谷称構造 / 原子差標 / 表面抗原 / preーS1領域 / preーS2領域 / コア抗原 / HBsAG outer dimer / ユア抗原 / 三次元構造予測 / 2分子会合体 / 小型球形粒子 / Dane粒子 / HBsAg outer dimer / inter-subunit disulphide bond / packing arrangement / aspaagine-linked sugar chain / sandwiched lipid / MARUZEN model / 不斉空間 / キラルリチウムアミド / 不斉脱プロトン化 / 不斉アルキル化 / 不斉プロトン化 / 不斉記憶 / 不斉付加 / 選択的グリコシル化 / 不斉α-アルキル化反応 / グリコシル化反応 / キラルホスフィンアミド / 不斉共役付加反応 / イミン / キレーション制御反応 / グリコシル化 / 有機銅 / 不斉アリル化 / ADAM & EVE / 立体選択的グリコシル化反応 / 有機リチウム / 立体選択的アリル化 / 生体高分子 / asymmetric space / chiral lithium amide / asymmetric deprotonation / asymmetric alkylation / asymmetric protonation / chiral memory / asymmetric addition / stereoselective glycosidation / ジヒドロ葉酸還元酵素 / 人工合成遺伝子 / レコンビナント蛋白質 / 葉酸拮抗剤 / 人口合成遺伝子 / Drug design / DHFR / Synthetic gene / Recombinant protein / Antifolate / マラリア / 抗マラリア薬 / スクリーニング / アンチセンス / 熱帯熱 / 原虫 / 標的分子 / ミトコンドリア / ATPase / マラリア治療薬 / スクリーニンヅ / インターネット / Malaria / Anti-malaria drug / Screening / antisense / tropical fever / protozoa / Plasmodium falciparum / target molecule / 蛋白質 / 一次構造 / 二次構造 / 高次構造 / 立体的表示 / HBsAg蛋白 / HGS分子模型 / マイクロコンピュータ / 磁気式原子座標測定装置 / AMBERプログラム / 原子座標合理化 / 三次元グラフィックス / 統計的分析 / 経験法測 / HGS精密分子構造模型 / 磁気的原子座標測定装置 / 三次元コンピュータ・グラフィックス / protein / amino acid sequence / secondary structure / quaternary structure / HBsAg protein / HGS plastic molecular modol / microcomputer / AMBER program / atomic coordinato rofinomont / コンピュータ薬物設計 / リード・ジェネレーション / コンピュータ・プログラム / Computer drug design / lead generation
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Research Projects
(
21
results)
Research Products
(
1
results)
Co-Researchers
(
42
People)
Project Start Year (Newest)
Project Start Year (Oldest)
Investigation of the molecular basis of the inhibitory effect of novel NF-kB inhibitor on bone invasion by OSCC for clinical trial
Principal Investigator
Matsuo Kou
Project Period (FY)
2014 – 2016
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Morphological basic dentistry
Research Institution
Kyushu Dental College
Development of Anti-malarial Drug and it's Molecular Target
Principal Investigator
WATAYA Yusuke
Project Period (FY)
1996 – 1999
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (A)
Research Institution
Okayama University
マラリアのジヒドロ葉酸還元酵素の構造解析と超分子形成に基づく選択的阻害剤の研究
Principal Investigator
Principal Investigator
板井 昭子
Project Period (FY)
1995
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Kitasato Institute
マラリアのジヒドロ葉酸還元酵素の構造解析と超分子形成に基づく選択的阻害剤の研究
Principal Investigator
Principal Investigator
板井 昭子
Project Period (FY)
1994
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
The University of Tokyo
Development of New Methoda for Lead Discovery Using Computer
Principal Investigator
Principal Investigator
ITAI Akiko
Project Period (FY)
1994 – 1995
Research Category
Grant-in-Aid for Developmental Scientific Research (B)
Research Field
医薬分子機能学
Research Institution
The Kitasato Institute
The University of Tokyo
医薬創製理論構築のための基盤的研究-探索・設計・評価
Principal Investigator
広部 雅昭
Project Period (FY)
1993
Research Category
Grant-in-Aid for Co-operative Research (B)
Research Field
医薬分子機能学
Research Institution
The University of Tokyo
Construction of Asymmetric Space
Principal Investigator
KOGA Kenji
Project Period (FY)
1993 – 1995
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
The University of Tokyo
Development of Novel Antimalarials
Principal Investigator
HORII Toshihiro
Project Period (FY)
1993 – 1995
Research Category
Grant-in-Aid for Developmental Scientific Research (B)
Research Field
寄生虫学(含医用動物学)
Research Institution
Osaka University
酵素の立体構造に基づく酵素阻害剤の論理的設研法の研究
Principal Investigator
Principal Investigator
板井 昭子
Project Period (FY)
1992
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Physical pharmacy
Research Institution
The University of Tokyo
複合系の分子機能
Principal Investigator
植木 正彬
Project Period (FY)
1991
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Tokyo University of Science
酵素阻害剤の論理的設計法の確立
Principal Investigator
Principal Investigator
板井 昭子
Project Period (FY)
1991
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Chemical pharmacy
Research Institution
The University of Tokyo
発がんプロモーター及び抗プロモーター化合物のコンピュータ分子設計と構造活性相関
Principal Investigator
Principal Investigator
板井 昭子
Project Period (FY)
1989
Research Category
Grant-in-Aid for Cancer Research
Research Institution
The University of Tokyo
複合系の分子機能
Principal Investigator
大野 雅二
Project Period (FY)
1989
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
The University of Tokyo
複合系の分子機能
Principal Investigator
大野 雅二
Project Period (FY)
1989 – 1991
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
The University of Tokyo
Refinement of Predicted Higher-Ordered Structure of Hepatitis B Surface Antigen Protein
Principal Investigator
NAGANO Kozo
Project Period (FY)
1989 – 1990
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
広領域
Research Institution
University of Tokyo
Development of computer system for generating drug structures based on drug-receptor interaction
Principal Investigator
Principal Investigator
ITAI Akiko
Project Period (FY)
1989 – 1991
Research Category
Grant-in-Aid for Developmental Scientific Research
Research Field
Chemical pharmacy
Research Institution
University of Tokyo
コンピュータを用いた酵素阻害剤の論理的分子設計に関する研究
Principal Investigator
Principal Investigator
板井 昭子
Project Period (FY)
1988
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Chemical pharmacy
Research Institution
The University of Tokyo
Development of computer drug design softwares for purpose of lead generation
Principal Investigator
IITAKA Yoichi
Project Period (FY)
1987 – 1988
Research Category
Grant-in-Aid for Developmental Scientific Research
Research Field
Physical pharmacy
Research Institution
Teikyo University
The University of Tokyo
発がんプロモーターの構造と有機化学研究
Principal Investigator
SHUDO Koichi
Project Period (FY)
1986
Research Category
Grant-in-Aid for Cancer Research
Research Institution
The University of Tokyo
How to Display Three-dimensional Structures of Proteins by Predictive Methods
Principal Investigator
NAGANO Kozo
Project Period (FY)
1986 – 1987
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
広領域
Research Institution
University of Tokyo
Development of new methods and softwares for drug design using computer graphics
Principal Investigator
Principal Investigator
ITAI Akiko
Project Period (FY)
1986 – 1988
Research Category
Grant-in-Aid for Developmental Scientific Research
Research Field
Chemical pharmacy
Research Institution
University of Tokyo
All
2014
All
Journal Article
[Journal Article] The novel IκB kinase β inhibitor IMD-0560 prevents bone invasion by oral squamous cell carcinoma.
2014
Author(s)
Tada Y, Kokabu S, Sugiyama G, Nakatomi C, Aoki K, Fukushima H, Osawa K, Sugamori Y, Ohya K, Okamoto M, Fujikawa T, Itai A, Matsuo K, Watanabe S, Jimi E.
Journal Title
Oncotarget
Volume
: 5
Pages
: 12317-12330
Peer Reviewed / Acknowledgement Compliant / Open Access
Data Source
KAKENHI-PROJECT-26462792
# of Projects (Dsc)
# of Projects (Asc)
1.
TOMIOKA Nobuo
(20202202)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
2.
斎藤 昭一
(80231330)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
3.
SHUDO Koichi
(50012612)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
4.
杉浦 幸雄
(40025698)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
5.
植木 正彬
(30084304)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
6.
NAGANO Kozo
(30012636)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
7.
IITAKA Yoichi
(90012591)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
8.
大野 雅二
(00111550)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
9.
大沢 利昭
(40012603)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
10.
Matsuo Kou
(70238971)
# of Collaborated Projects:
1 results
# of Collaborated Products:
1 results
11.
KOGA Kenji
(10012600)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
12.
NAKAMURA Eiichi
(00134809)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
13.
TOMIOKA Kiyoshi
(50114575)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
14.
MUKAIYAMA Teruaki
(60016003)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
15.
FUJI Kaoru
(20027056)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
16.
HORII Toshihiro
(80142305)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
17.
TAI Kumiko
(00187907)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
18.
MITAMURA Toshihide
(80268846)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
19.
MORIMATSU Katsumi
(70263308)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
20.
ENDO Yasuyuki
(80126002)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
21.
IWAI Yuzuru
(70099977)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
22.
WATAYA Yusuke
(90127598)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
23.
KITA Kiyoshi
(90134444)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
24.
MATSUDA Akira
(90157313)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
25.
SEKIMIZU Kazuhisa
(90126095)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
26.
KIMURA Masatsugu
(60195378)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
27.
豊島 聰
(40092283)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
28.
小林 進
(70101102)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
29.
広部 雅昭
(20012594)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
30.
高野 達哉
(40124995)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
31.
柴崎 正勝
(30112767)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
32.
野村 靖幸
(00034041)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
33.
北川 勲
(20028830)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
34.
自見 英治郎
(40276598)
# of Collaborated Projects:
1 results
# of Collaborated Products:
1 results
35.
藤川 智行
(30451074)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
36.
太田 敏晴
(50114418)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
37.
小清水 弘一
(90026518)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
38.
坂井 進一郎
(20009161)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
39.
平田 義正
(10022493)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
40.
杉山 智彦
(90252709)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
41.
MORIYAMA Yoshiuori
(10150658)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
42.
張ヶ谷 泰二
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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