Inoue Akira 井上晃

… Alternative Names

INOUE Akira 井上晃

井上晃イノウエアキラ

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Researcher Number	50109857
Other IDs
Affiliation (based on the past Project Information) *help	2022 – 2023: 大阪公立大学, 大学院医学研究科, 研究員 2015 – 2021: 大阪市立大学, 大学院医学研究科, 研究員 2011: 大阪市立大学, 大学院・理学研究科, 研究員 2009 – 2011: Osaka City University, 大学院・医学研究科, 研究員 2006: OSAKA CITY UNIVERSITY, GRADUATE SCHOOL OF MEDICINE, Associate Professor, 大学院医学研究科, 助教授 … More 2005: 大阪市立大学, 大学院・医学系研究科, 助教授 2004 – 2005: 大阪市立大学, 大学院・医学研究科, 助教授 1999 – 2000: 大阪市立大学, 医学部, 助教授 1997: 大阪市立大学, 医学部, 助教授 1993: 大阪市立大学, 医学部, 助教授 Less
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Bio-related chemistry / Chemistry related to living body Except Principal Investigator Basic Section 52030:Psychiatry-related / Basic Section 52050:Embryonic medicine and pediatrics-related / General anatomy (including Histology/Embryology) / Psychiatric science / General anatomy (including Histology/Embryology)
Keywords	Principal Investigator スプライシング制御因子 / S1-1 nuclear body / 活動度の自己調節機構 / 細胞分裂機構とRBM10 / RBM10遺伝子変異と疾病 / splicing regulator / RBM10/S1-1 / RBM10 / 転写制御 / 膵臓ガン患者の延命 … More / 延命を可能にする遺伝子変異 / がん / RBM10のWikipedia改訂 / RBM10の総説執筆 / Wikipediaの全面改訂 / 当該遺伝子の総説執筆 / Splicing 制御 / 原著論文 IJMSに発表 / RBM10 遺伝子総説 / Wikipedia (英語版)全面改訂 / 総説 RBM10 / RBM10異常に由来する疾病群 / RBM10異常と細胞病態 / RBM10標的転写産物の網羅的同定 / X-linked 遺伝子 / 細胞内RBM10レベルの制御機構 / RBM10によるG2/M期arrest / 細胞分裂制御 / RBM10活性の制御機構 / RBM10異常による細胞病態と疾病 / RBM10が関わる細胞内過程 / RBM10標的遺伝子の同定 / 選択的スプライシング / RBM10制御下の遺伝子群 / RBM10/ S1-1 / C2H2 Zn finger / アイソフォーム1と2 / 抗がん剤 / Fas / スプラーシング制御 / S1-1 nuclear body targeting sequence / 核移行配列 / がん危険遺伝子 / アポトーシス関連遺伝子 / スプライシング制御 / S1-1 / プロセシング / RNA / 翻訳制御 / 二元性タンパク質 / 転写後制御 / 転写因子 / ビメンチン中間径繊維 / hnRNP蛋白質 / S1蛋白質 … More Except Principal Investigator RBM10 / nuclear body / PML / 統合失調症 / apoptosis / 細胞死 / p53 / Aplysia / 精神病 / 抗核抗体 / ミクログリア / スプライシング / 感情障害 / クロマチン / 核タンパク質 / 精子形成 / 選択的スプライシング / 男性不妊症 / 精子形成不全 / casein kinase / tumor suppressor gene / protein phosphorylation / tumor cells / 老化シグナル / S1-1 / 核内輸送機能 / 老化細胞 / ヌクレオボディ / カゼインキナーゼ / 癌抑制遺伝子 / ヌクレオボデイ / リン酸化 / 腫瘍細胞 / schizophrenia / NMDA receptor / glutamate / D-serine / グルタミン酸 / NMDA受容体 / D-セリン / functional domain / nuclear translocation / anchoring function / vimentin / cytoskeleton / 核移行反応 / 機能ドメイン解析 / 核内移行反応 / アンカー機能 / ビメンチン / 細胞骨格 / Hsp70 / Heme oxygenase / スーパーオキシドジスムターゼ / スーパーオキシド / 血液循環 / ストレス Less

細胞核ダイナミクスの分子機能に着目した抗核抗体関連精神疾患の解明
- Principal Investigator
  
  山本直樹
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  International University of Health and Welfare
Elucidation of the pathogenesis of azoospermia caused by deficiency of the RNA-binding protein RBM10 and exploration of treatment methods
- Principal Investigator
  
  Kunimoto Hiroyuki
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Osaka Metropolitan University
  Osaka City University
Mutations for life lengthening of pancreatic cancer patients: mechanism and proposed theory for practicePrincipal Investigator
- Principal Investigator
  
  INOUE Akira
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Osaka Metropolitan University
  Osaka City University
Unified elucidation of cell pathology of various diseases stemming from alternative splicing regulator RBM10Principal Investigator
- Principal Investigator
  
  Inoue Akira
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bio-related chemistry
- Research Institution
  Osaka City University
The splicing factor and diseases caused by its anomalyPrincipal Investigator
- Principal Investigator
  
  INOUE Akira
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Osaka City University
A study about the impaired mitochondrial membrane potential and nuclear body formation, and their relationship with the induction of cell senescence and cell death
- Principal Investigator
  
  NISHIO Koji
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  NAGOYA UNIVERSITY
Study on the mechanism of neural D-serine metabolism and application for the pharmacotherapeutics of schizophrenia
- Principal Investigator
  
  YAMAMOTO Naoki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Tokyo Medical and Dental University
NUCLEAR PROTEIN-ANCHORING FUNCTION OF CYTOSKELETON AND ITS ANTI-APOPTOTIC EFFECTS AGAINST P53-DEPENDENT APOPTOSIS.
- Principal Investigator
  
  NISHIO Koji
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  NAGOYA UNIVERSITY
細胞内mRNA局在化における細胞骨格会合性のパラダイムPrincipal Investigator
- Principal Investigator
  
  井上晃
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka City University
ストレス蛋白発現における活性酵素の役割
- Principal Investigator
  
  井上正康
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka City University

All 2023 2021 2020 2019 2017 2016 2011 2005

All Journal Article Presentation Book

[Book] RBM102021
- Author(s)
  Akira Inoue
- Total Pages
  18
- Publisher
  Wikipedia
- Data Source
  KAKENHI-PROJECT-19K08378
[Journal Article] 精神疾患の新規薬物標的としての細胞核転写後調節機構.2023
- Author(s)
  山本直樹, 中谷善彦, 井上晃, 西川徹
- Journal Title
  
  細胞
  
  Volume: 55 Pages: 835-839
- Data Source
  KAKENHI-PROJECT-21K07557
[Journal Article] RBM10: Structure, functions, and associated diseases2021
- Author(s)
  Inoue Akira
- Journal Title
  
  Gene
  
  Volume: 783 Pages: 145463-145463
- DOI
  10.1016/j.gene.2021.145463
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08327, KAKENHI-PROJECT-19K08378
[Journal Article] Sequestration of RBM10 in Nuclear Bodies: Targeting Sequences and Biological Significance2021
- Author(s)
  Wang Ling-Yu、Xiao Sheng-Jun、Kunimoto Hiroyuki、Tokunaga Kazuaki、Kojima Hirotada、Kimura Masatsugu、Yamamoto Takahiro、Yamamoto Naoki、Zhao Hong、Nishio Koji、Tani Tokio、Nakajima Koichi、Sunami Kishiko、Inoue Akira
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 19 Pages: 10526-10526
- DOI
  10.3390/ijms221910526
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08327, KAKENHI-PROJECT-19K08378, KAKENHI-PROJECT-21K06174, KAKENHI-PROJECT-21K07557
[Journal Article] RBM10 regulates centriole duplication in HepG2 cells by ectopically assembling PLK4‐STIL complexes in the nucleus2020
- Author(s)
  Kunimoto Hiroyuki、Inoue Akira、Kojima Hirotada、Yang Junhao、Zhao Hong、Tsuruta Daisuke、Nakajima Koichi
- Journal Title
  
  Genes to Cells
  
  Volume: 25(2) Issue: 2 Pages: 100-110
- DOI
  10.1111/gtc.12741
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08327, KAKENHI-PROJECT-19K08378
[Journal Article] Targeting of RBM10 to S1-1 Nuclear Bodies: Targeting Sequences and its Biological Significance2019
- Author(s)
  L.-Y. Wang, S.-J. Xiao, H. Kunimoto, K. Tokunaga, H. Kojima, M. Kimura, T. Yamamoto, N.Yamamoto, Z. Hong, K. Nishio, H Yamane, T. Tani, K. Nakajima, H. Iguchi, and A. Inoue
- Journal Title
  
  bioRkiv
  
  Volume: -
- DOI
  10.1101/516831
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K05569
[Journal Article] Phospho-Ser727 of STAT3 regulates STAT3 activity by enhancing dephosphory-lation of phospho-Tyr705 largely through TC452011
- Author(s)
  Ryohei Wakahara, Hiroyuki Kunimoto, Kanae Tanino, Hirotada Kojima, Akira Inoue, Haruo Shintaku and Koichi Nakajima
- Journal Title
  
  Genes to Cells
  
  Volume: 17 Issue: 2 Pages: 132-145
- DOI
  10.1111/j.1365-2443.2011.01575.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21550162, KAKENHI-PROJECT-21590316, KAKENHI-PROJECT-21590317
[Journal Article] Association of hnRNP S1 proteins with vimentin intermediate filaments in migrating cells.2005
- Author(s)
  Akira Inoue
- Journal Title
  
  Journal of Cell Science 118
  
  Pages: 2303-2311
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590159
[Journal Article] Association of hnRNP S1 proteins with vimentin intermediate filaments in migrating cells.2005
- Author(s)
  akira Inoue
- Journal Title
  
  Journal of Cell Science 118
  
  Pages: 2303-2311
- Data Source
  KAKENHI-PROJECT-17590159
[Journal Article] Association of hnRNP S1 proteins with vimentin intermediate filaments in migrating cells.2005
- Author(s)
  Inoue A et al.
- Journal Title
  
  J Cell Sci 118
  
  Pages: 2303-2311
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591125
[Presentation] 細胞核RNAスプライシング制御因子RBM10の中枢神経系及び末梢組織における発現と機能2023
- Author(s)
  山本直樹、中谷善彦、樫村剛、熊谷望海、須藤千晴、塙雄大、生井莉奈子、黒川信、國本浩之、井上晃
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-19K08327
[Presentation] 細胞核RNAスプライシング制御因子RBM10の中枢神経系及び末梢神経組織における発現と機能2023
- Author(s)
  山本直樹, 中谷善彦, 樫村剛, 熊谷望海, 須藤千晴, 塙裕大, 生井莉奈子, 黒川信, 國本浩之, 井上晃
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-21K07557
[Presentation] RBM10はHepG2において中心小体複製に関わる新規の調節因子である2019
- Author(s)
  國本浩之, 井上晃, 趙虹, 中嶋弘一
- Organizer
  第42回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K08327
[Presentation] RBM10はHepG2において中心小体複製に関わる新規の調節因子である.2019
- Author(s)
  國本浩之, 井上晃, 趙虹, 中嶋弘一
- Organizer
  第42回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K08378
[Presentation] RBM10による中心小体形成の制御機序について2017
- Author(s)
  國本浩之、趙虹、井上晃、中嶋弘一
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-15K05569
[Presentation] RBM10の活動度を制御する自己調節機構： S1-1 NB-targeting2017
- Author(s)
  井上晃, 國本浩之, 王凌宇, 肖勝軍, 小島裕正, 山本隆博, 山本直樹, 木村政継, 徳永和明, 谷時雄, 中嶋弘一, 井口広義
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-15K05569
[Presentation] RBM10過剰発現による増殖抑制機序の解析2016
- Author(s)
  國本浩之、趙虹、井上晃、中嶋弘一
- Organizer
  第39回日本分子生物学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜）
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-15K05569

1. NAKAJIMA Koichi (00227787)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
2. YAMAMOTO Naoki (70312296)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
3. Kunimoto Hiroyuki (80372853)

# of Collaborated Projects: 4 results

# of Collaborated Products: 10 results
4. KOJIMA Hirotada (40336772)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. NISHIO Koji (60252235)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. TATSUMI Hitoshi (20171720)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TONE Shigenobu (70211399)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. HONDA Takashi (20165608)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KASHIWA Atsushi (10301227)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 井上正康 (80040278)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 佐藤英介 (60211942)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 高橋研一 (40089959)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 濱崎考史 (40619798)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Inoue Akira 井上 晃

INOUE Akira 井上 晃

井上 晃 イノウエ アキラ

Research Projects

Research Products

Co-Researchers

細胞核ダイナミクスの分子機能に着目した抗核抗体関連精神疾患の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the pathogenesis of azoospermia caused by deficiency of the RNA-binding protein RBM10 and exploration of treatment methods

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mutations for life lengthening of pancreatic cancer patients: mechanism and proposed theory for practicePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Unified elucidation of cell pathology of various diseases stemming from alternative splicing regulator RBM10Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The splicing factor and diseases caused by its anomalyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A study about the impaired mitochondrial membrane potential and nuclear body formation, and their relationship with the induction of cell senescence and cell death

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the mechanism of neural D-serine metabolism and application for the pharmacotherapeutics of schizophrenia

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

NUCLEAR PROTEIN-ANCHORING FUNCTION OF CYTOSKELETON AND ITS ANTI-APOPTOTIC EFFECTS AGAINST P53-DEPENDENT APOPTOSIS.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

細胞内mRNA局在化における細胞骨格会合性のパラダイムPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

ストレス蛋白発現における活性酵素の役割

Principal Investigator

Project Period (FY)

Research Category

Research Institution

[Book] RBM102021

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] 精神疾患の新規薬物標的としての細胞核転写後調節機構.2023

Author(s)

Journal Title

Data Source

[Journal Article] RBM10: Structure, functions, and associated diseases2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sequestration of RBM10 in Nuclear Bodies: Targeting Sequences and Biological Significance2021

Author(s)

Inoue Akira 井上晃

INOUE Akira 井上晃

井上晃イノウエアキラ