Nishibori Masahiro 西堀正洋

… Alternative Names

NISHIBORI Masahiro 西堀正洋

西堀正洋ニシボリマサヒロ

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Researcher Number	50135943
Other IDs
Affiliation (Current)	2025: 岡山大学, 医歯薬学総合研究科, 特命教授 2025: 岡山大学, 医歯薬学域, 教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 岡山大学, 医歯薬学総合研究科, 特命教授 2016 – 2020: 岡山大学, 医歯薬学総合研究科, 教授 2015: 岡山大学, 大学院医歯薬学総合研究科, 教授 2011 – 2015: 岡山大学, 医歯(薬)学総合研究科, 教授 2014: 岡山大学, 医歯薬総合研究科, 教授 … More 2013: 岡山大学, 医歯薬学総合研究科, 教授 2005 – 2012: Okayama University, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Professor, 大学院・医歯薬学総合研究科, 教授 2005 – 2006: 岡山大学, 大学院医歯薬学総合研究科, 教授 2003 – 2004: 岡山大学, 大学院・医歯学総合研究科, 教授 1997 – 1998: 岡山大学, 医学部, 助教授 1993 – 1994: 岡山大学, 医学部, 講師 1988 – 1989: 岡山大学, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator General pharmacology / General pharmacology / Applied pharmacology / Basic Section 48030:Pharmacology-related / Infectious disease medicine / Cerebral neurosurgery Except Principal Investigator Applied pharmacology / General pharmacology / Basic Section 50010:Tumor biology-related / General pharmacology … More / Basic Section 55030:Cardiovascular surgery-related / Basic Section 52050:Embryonic medicine and pediatrics-related / Basic Section 55040:Respiratory surgery-related / Basic Section 57030:Conservative dentistry-related / Basic Section 49010:Pathological biochemistry-related / Basic Section 48030:Pharmacology-related / Periodontology / Biological pharmacy / Circulatory organs internal medicine / Digestive surgery / Ophthalmology Less
Keywords	Principal Investigator HMGB1 / 敗血症 / 脳浮腫 / Trypsin / Thrombin / Proteinase / Neuron / Apoptosis / Serine proteinase inhibitor / ARDS … More / HRG / 抗体医薬 / 脳外傷 / 血液脳関門 / ニューロン / プロテアーゼ / 抗HMGB1抗体 / サイトカイン類 / 血管内皮細胞 / トランスロケーション / トランスレーションリサーチ / 蛋白質 / Immunothrombus / トランスレーショナルリサーチ / 薬理学 / polymyxin / sepsis / cytokine / complex / plasma protein / interaction / adhesion molecule / leukocyte / 薬物標的 / プロテオミクス / 細胞接着分子 / 細胞間相互作用 / 白血球 / トリプシン / トロンビン / アポトーシス / セリンプロテアーゼインヒビター / 致死性 / CLPモデル / 多臓器不全 / 好中球 / 組換えタンパク製剤 / 補充療法 / Immunothrombosis / 脳腫瘍 / ミクログリア / 脊髄損傷 / グリチルリチン / 血液-脳関門 / アストログリア細胞 / 脳血管透過性 / 中枢・末梢神経 / LTP / ウエスタンブロット / ヌクレオサイトカイン / 敗血漿 / アストログリア / セルピン / 線維芽細胞 / トランスメンブレン4 / 血小板 / CD63 / Granulophysin … More Except Principal Investigator HMGB1 / 炎症 / HRG / マクロファージ / 抗体医薬 / 血液脳関門 / 脳梗塞 / ヒスタミン / 受容体 / がん / 阻害作用 / 転移 / S100A8/A9 / 虚血再灌流障害 / 歯周病 / 高ヒスチジン糖タンパク / 血管新生 / ホメオダイナミクス / 中和抗体 / PAR-2 / 単球 / 慢性炎症 / 抗HMGB1抗体 / 薬物治療学 / 脳浮腫 / AGE / 接着分子 / RAGE / ミクログリア / 抗体治療 / がん転移抑制タンパク質 / モノクローナル抗体 / HMGB-1 / 脊髄保護 / 脊髄麻痺 / 対麻痺 / 胸部大動脈手術 / 予防法 / 炎症反応 / 脊髄血液関門 / 対麻痺予防 / 大動脈手術 / うさぎ / 脊髄虚血 / 川崎病 / S100A8/A9中和抗 / H R G / 脳転移 / 肺移植 / HMGB１ / 幹細胞 / 創傷治癒 / 低栄養 / 胎盤形成 / 妊娠高血圧 / 血圧 / 妊娠 / 高血圧 / 高ヒスチジン血漿タンパク / 胎盤 / 血管リモデリング / トロホブラスト / 妊娠高血圧症候群 / メディエーター / ニッチ / M2 polarization / 造血幹細胞ニッチ / 脳組織ニッチ / 遺伝子 / 免疫学 / 歯学 / 抗体療法 / 炎症性サイトカイン / 歯周炎 / 好中球 / 歯肉上皮細胞 / サイトカイン / 硬膜外出血 / 脳出血 / 脳血管攣縮 / 硬膜下出血 / 脳内出血 / 遅発性血管攣縮 / 出血性脳卒中 / 生活習慣病 / 遺伝子発現 / 肝 / DAMPs / 血漿タンパク / 敗血症 / 急性炎症 / マクロファージ分化 / 骨髄ニッチ / マクローファージ分化 / 血管内皮細胞 / 組織修復機構 / vessel spas / inflammation / infarction / brain ischemia / macronharee / monocyte / coronary ischemia / counteract antibody / neucleokine / 血管攣縮 / 梗塞 / 脳血管疾患 / 虚血性心疾患 / ヌクレオカイン / plasma / 血漿 / cell-growth / DIC / PAR-1 / trypsin / thrombin / serine-protease / protease-activated-receptor / MAP kinase / PKC / 大腸癌細胞 / プロテアーゼ活性化受容体 / nafamostat mesilate / 肥満細胞 / 大腸癌 / PGE2 / 細胞増殖促進 / 肥満細胞トリプターゼ / プロテアーゼ活性化型受容体 / macrophages / Kupffer cells / Propionibacterium acnes / Lipopolysaccharide / IL-18 / knockout mice / hepatic injury / H2-receptors / histamine / アポトーシス / 細胞間シグナル伝達 / HDC / 肝炎治療 / プロステグランディン / 肝炎 / アドレナリン / プロスタグランディン / H2受容体 / インターロイキン18 / 絶食 / L-ヒスチジン / ヒスタミン作動神経 / ヒスタミン代謝 / 糖尿病 / 終末糖化産物 / 糖尿病網膜症 / 治療 / 加齢黄斑変性 / 神経細胞 / アストロサイト / 神経 / アミロイドβ / アルツハイマー / 血液ー脳関門 / 血液-脳関門 / 霊長類動物 / high mobility group box1 / 高血圧症 / SHR / High mobility group box1 / 抗腫瘍薬 / ヒト抗RAGE抗体 / オータコイド / 活性酸素 / 単球・マクロファージ / B細胞リンパ腫 / μ-受容体 / モルヒネ / 線条体 / 無麻酔無拘束ラット / マイクロダイアリシス法 / 高速液体クロマトグラフィ- / セロトニン / ドパミン / ノルアドレナリン / 神経性取り込み / 脳内モノアミン / Hi受容体拮抗薬 / 抗ヒスタミン薬 Less

S100A8/A9-向転移とHRG-抗転移の細胞間・分子間クロストークの解明
- Principal Investigator
  
  阪口政清
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Okayama University
Development of new therapeutic drug for Kawasaki disease focusing on HMGB1-HRG balance
- Principal Investigator
  
  Baba Kenji
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Okayama University
Verification of preventative effects of monoclonal HMGB1 antibody for spinal cord injury after aortic operation
- Principal Investigator
  
  村岡玄哉
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Kawasaki Medical School
  Okayama University
Therapeutic effects of anti-HMGB1 monoclonal antibody on lung ischemia reperfusion injury in mice
- Principal Investigator
  
  OTANI SHINJI
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Ehime University
  Okayama University
Identification of HRG that is highly inhibitory to S100A8/A9-mediated organ tropic cancer metastasis
- Principal Investigator
  
  Sakaguchi Masakiyo
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Okayama University
Roles of histidine-rich glycoprotein in prevention of hypertensive disorders of pregnancy and in physiological placental development.
- Principal Investigator
  
  Teshigawara Kiyoshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Okayama University
Malnutrition delayed wound healing by HMGB1-related prolonged inflammation
- Principal Investigator
  
  Yamashiro Keisuke
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Kobe Tokiwa Junior College
  Okayama University
Analysis dynamics of HMGB1 as a biosensor molecule and its multiple functionsPrincipal Investigator
- Principal Investigator
  
  Nishibori Masahiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Okayama University
Basic study of the niche function improvement medicine development that targeted a homeodynamics-related mediator
- Principal Investigator
  
  TAKAHASHI Hideo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Kindai University
Functional characterization of histidine-rich glycoprotein (HRG) under the inflammatory conditions.
- Principal Investigator
  
  Teshigawara Kiyoshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Okayama University
Therapeutic Potential of an Anti-High Mobility Group Box1 Monoclonal Antibody in Hemorrhagic stroke
- Principal Investigator
  
  RYU katsuyaku
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Okayama University
Functional analysis of HMGB1 as an inflammatory mediator in periodontitis
- Principal Investigator
  
  YAMASHIRO KEISUKE
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Periodontology
- Research Institution
  Okayama University
Research for homeodynamics regeneration-promoting drug discovery
- Principal Investigator
  
  TAKAHASHI Hideo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kindai University
Mechanism for microthrombus formation on NETosis and development of therapy for ARDS.Principal Investigator
- Principal Investigator
  
  Nishibori Masahiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Okayama University
Novel therapeutic strategy targeting advanced glycation end product
- Principal Investigator
  
  Shiraga Fumio
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Okayama University
A novel pathological mechanism of Alzheimer's disease as a chronic inflammation through RAGE signal activity.
- Principal Investigator
  
  Teshigawara Kiyoshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Okayama University
Drug development for sepsis by regulation of neutrophilsPrincipal Investigator
- Principal Investigator
  
  NISHIBORI MASAHIRO
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Infectious disease medicine
- Research Institution
  Okayama University
Drug development for brain and spinal cord trauma targeting HMGB1Principal Investigator
- Principal Investigator
  
  NISHIBORI Masahiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Okayama University
Basic scientific research for formulating drugs for treatment of hypertension
- Principal Investigator
  
  TAKAHASHI Hideo
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kinki University
Development of monoclonal antibodies therapy for cerebral infarction and cerebral edema in primate animal mode
- Principal Investigator
  
  RYU katsuyaku
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Okayama University
Development oftherapy for acute traumatic brain injuryPrincipal Investigator
- Principal Investigator
  
  NISHIBORI Masahiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Okayama University
The development of broad-spectrum antitumor agents with anti-HMGB1 antibody and clarification of its action mechanism
- Principal Investigator
  
  WAKE HIDENORI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Okayama University
Mechanism for HMGB-or HMGB1-derived peptide-induced increase in BBB permeabilityPrincipal Investigator
- Principal Investigator
  
  NISHIBORI Masahiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Okayama University
Development of monoclonal antibodies therapy for cerebral infarction and cerebral edema
- Principal Investigator
  
  RYU Katsuyaku
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Okayama University
脳浮腫の発生機序解明と創薬標的の同定Principal Investigator
- Principal Investigator
  
  西堀正洋
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied pharmacology
- Research Institution
  Okayama University
A novel anti-HMGB1 Ab therapy for treatment of B-cell lymphoma
- Principal Investigator
  
  TAKAHASHI Hideo
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Okayama University
Development of antibody therapy for brain infarction
- Principal Investigator
  
  RYU Katsuyaku
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Okayama University
虚血性脳障害と学習・記憶過程に共通する原理の探索研究Principal Investigator
- Principal Investigator
  
  西堀正洋
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Okayama University
The Effects of HMGB1 on Ischemia-Reperfusion Injury in the Rat Heart.
- Principal Investigator
  
  TAKAHASHI Hideo
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Okayama University
サイトカイン活性を有する核転写因子、ヌクレオサイトカインの情報伝達と敗血症病態Principal Investigator
- Principal Investigator
  
  西堀正洋
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Applied pharmacology
- Research Institution
  Okayama University
Study on regulation of tissue remodeling by histidine rich plasma factors
- Principal Investigator
  
  MORI Shuji
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Okayama University
Proteomics analysis of plasma protein complex regulating leukocyte interaction.Principal Investigator
- Principal Investigator
  
  NISHIBORI Masahiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  OKAYAMA UNIVERSITY
Inducible histamine protects mice from P.acnes-primed and LPS-induced hepatitis through H2-receptor stimulation
- Principal Investigator
  
  TAKAHASHI Hideo
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  OKAYAMA UNIVERSITY
The analysis of the molecular physiology of the protease-activated receptors in digestive system disease
- Principal Investigator
  
  IWAGAKI Hiromi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Okayama University
A role of a novel brain-derived proteinase inhibitor in the apoptosis in neuronsPrincipal Investigator
- Principal Investigator
  
  NISHIBORI Masahiro
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Okayama University
脳由来の新しいセルピン様蛋白質の構造と機能に関する研究Principal Investigator
- Principal Investigator
  
  西堀正洋
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Okayama University
脳内微量透析法によるオピオイド系とヒスタミン系の相互作用に関する研究
- Principal Investigator
  
  大石了三
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Okayama University
CD63関連遺伝子クローニングとその蛋白機能解析Principal Investigator
- Principal Investigator
  
  西堀正洋
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Okayama University
脳のモノアミン類の神経性取り込みに及ぼす抗ヒスタミン薬の影響に関する研究
- Principal Investigator
  
  佐伯清美
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Okayama University
実験的糖尿病マウスにおける中枢ヒスタミン作動ニューロン機能に関する研究
- Principal Investigator
  
  佐伯清美
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Okayama University

[Book] HMGB1とその受容体型研究の現状と展望2016
- Author(s)
  高橋英夫、西堀正洋
- Total Pages
  9
- Publisher
  日本臨床
- Data Source
  KAKENHI-PROJECT-15K08253
[Journal Article] The plasma protein HRG is an important factor for preventing sepsis and maintaining homeostatic response2024
- Author(s)
  Nishibori Masahiro、Wake Hidenori、Sakaguchi Masakiyo
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 159 Issue: 2 Pages: 107-111
- DOI
  10.1254/fpj.23027
- ISSN
  0015-5691, 1347-8397
- Year and Date
  2024-03-01
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K27439
[Journal Article] Phosphorylated SARM1 is involved in the pathological process of rotenone-induced neurodegeneration2023
- Author(s)
  Murata Hitoshi、Phoo May Tha Zin、Ochi Toshiki、Tomonobu Nahoko、Yamamoto Ken-ichi、Kinoshita Rie、Miyazaki Ikuko、Nishibori Masahiro、Asanuma Masato、Sakaguchi Masakiyo
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 174 Issue: 6 Pages: 533-548
- DOI
  10.1093/jb/mvad068
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14595, KAKENHI-PROJECT-22K06884, KAKENHI-PROJECT-23K06717, KAKENHI-PROJECT-23K06928, KAKENHI-PROJECT-21K07415, KAKENHI-PROJECT-22K20793, KAKENHI-PROJECT-23K27439
[Journal Article] Role of neuron-derived ATP in paclitaxel-induced HMGB1 release from macrophages and peripheral neuropathy2022
- Author(s)
  Domoto Risa、Sekiguchi Fumiko、Kamaguchi Riki、Iemura Maiko、Yamanishi Hiroki、Tsubota Maho、Wang Dengli、Nishibori Masahiro、Kawabata Atsufumi
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 148 Issue: 1 Pages: 156-161
- DOI
  10.1016/j.jphs.2021.11.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03408, KAKENHI-PROJECT-21K06608
[Journal Article] Decreased Levels of Histidine-Rich Glycoprotein and Increased Levels of High-Mobility Group Box 1 are Risk Factors for Refractory Kawasaki Disease2022
- Author(s)
  Namba T, Yashiro M, Fujii Y, Tsuge M, Liu K, Nishibori M, Tsukahara H
- Journal Title
  
  Mod Rheumatol
  
  Volume: - Issue: 3 Pages: 599-607
- DOI
  10.1093/mr/roac040
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07822, KAKENHI-PROJECT-22K07935, KAKENHI-PROJECT-22K07820
[Journal Article] Central high mobility group box-1 induces mechanical hypersensitivity with spinal microglial activation in a mouse model of hemi-Parkinson’s disease2022
- Author(s)
  Sato Fumiaki、Nakamura Yoki、Ma Simeng、Kochi Takahiro、Hisaoka-Nakashima Kazue、Wang Dengli、Liu Keyue、Wake Hidenori、Nishibori Masahiro、Morioka Norimitsu
- Journal Title
  
  Biomedicine & Pharmacotherapy
  
  Volume: 145 Pages: 112479-112479
- DOI
  10.1016/j.biopha.2021.112479
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18476, KAKENHI-PROJECT-19H03408
[Journal Article] Caspase-Dependent HMGB1 Release from Macrophages Participates in Peripheral Neuropathy Caused by Bortezomib, a Proteasome-Inhibiting Chemotherapeutic Agent, in Mice2021
- Author(s)
  Tsubota Maho、Miyazaki Takaya、Ikeda Yuya、Hayashi Yusuke、Aokiba Yui、Tomita Shiori、Sekiguchi Fumiko、Wang Dengli、Nishibori Masahiro、Kawabata Atsufumi
- Journal Title
  
  Cells
  
  Volume: 10 Issue: 10 Pages: 2550-2550
- DOI
  10.3390/cells10102550
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03408, KAKENHI-PROJECT-21K06608
[Journal Article] Combinatrial treatment of anti-High Mobility Group Box-1 monoclonal antibody and epothilone B improves functional recovery after spinal cord contusion injury2021
- Author(s)
  Zhu Yicheng、Uezono Naohiro、Yasui Tetsuro、Nakajo Masahide、Nagai Tatsuya、Wang Dengli、Nishibori Masahiro、Nakashima Kinichi
- Journal Title
  
  Neuroscience Research
  
  Volume: 172 Pages: 13-25
- DOI
  10.1016/j.neures.2021.04.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03408
[Journal Article] Understanding of COVID-19 Pathology: Much More Attention to Plasma Proteins2021
- Author(s)
  Nishibori Masahiro、Stonestreet Barbara S.
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 12 Pages: 656099-656099
- DOI
  10.3389/fimmu.2021.656099
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03408
[Journal Article] High‐mobility group box‐1 and inter‐alpha inhibitor proteins: In vitro binding and co‐localization in cerebral cortex after hypoxic‐ischemic injury2021
- Author(s)
  Hatayama Kazuki、Chen Ray H.、Hanson Jordan、Teshigawara Kiyoshi、Qiu Joseph、Santoso Andre、Disdier Cl?mence、Nakada Sakura、Chen Xiaodi、Nishibori Masahiro、Lim Yow‐Pin、Stonestreet Barbara S.
- Journal Title
  
  The FASEB Journal
  
  Volume: 35 Issue: 3
- DOI
  10.1096/fj.202002109rr
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03408, KAKENHI-PROJECT-19K07401
[Journal Article] Advanced glycation end-products reduce lipopolysaccharide uptake by macrophages2021
- Author(s)
  Kitaura Atsuhiro、Nishinaka Takashi、Hamasaki Shinichi、Hatipoglu Omer Faruk、Wake Hidenori、Nishibori Masahiro、Mori Shuji、Nakao Shinichi、Takahashi Hideo
- Journal Title
  
  PLOS ONE
  
  Volume: 16 Issue: 1 Pages: 0245957-0245957
- DOI
  10.1371/journal.pone.0245957
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06905, KAKENHI-PROJECT-18K15035, KAKENHI-PROJECT-20K17799
[Journal Article] Histidine-Rich Glycoprotein Stimulates Human Neutrophil Phagocytosis and Prolongs Survival through CLEC1A.2021
- Author(s)
  Takahashi Y, Wake H, Sakaguchi M, Yoshii Y, Teshigawara K, Wang D, Nishibori M.
- Journal Title
  
  J Immunol.
  
  Volume: 206(4) Issue: 4 Pages: 737-750
- DOI
  10.4049/jimmunol.2000817
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07401, KAKENHI-PROJECT-16H06277
[Journal Article] Leukocyte‐Derived High‐Mobility Group Box 1 Governs Hepatic Immune Responses to <i>Listeria monocytogenes</i>2021
- Author(s)
  Volmari Annika、Foelsch Katharina、Zierz Elisabeth、Yan Karsten、Qi Minyue、Bartels Karlotta、Kondratowicz Stephanie、Boettcher Marius、Reimers Daniel、Nishibori Masahiro、Liu Keyue、Schwabe Robert F.、Lohse Ansgar W.、Huber Samuel、Mittruecker Hans‐Willi、Huebener Peter
- Journal Title
  
  Hepatology Communications
  
  Volume: 5 Issue: 12 Pages: 2104-2120
- DOI
  10.1002/hep4.1777
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03408
[Journal Article] Neuroprotective Effects of Anti-high Mobility Group Box-1 Monoclonal Antibody Against Methamphetamine-Induced Dopaminergic Neurotoxicity2021
- Author(s)
  Masai Kaori、Kuroda Keita、Isooka Nami、Kikuoka Ryo、Murakami Shinki、Kamimai Sunao、Wang Dengli、Liu Keyue、Miyazaki Ikuko、Nishibori Masahiro、Asanuma Masato
- Journal Title
  
  Neurotoxicity Research
  
  Volume: 39 Issue: 5 Pages: 1511-1523
- DOI
  10.1007/s12640-021-00402-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07993, KAKENHI-PROJECT-19H03408, KAKENHI-PROJECT-21K07415
[Journal Article] Anti-high mobility group box 1 monoclonal antibody suppressed hyper-permeability and cytokine production in human pulmonary endothelial cells infected with influenza A virus2021
- Author(s)
  Namba T, Tsuge M, Yashiro M, Saito Y, Liu K, Nishibori M, Morishima T, Tsukahara H
- Journal Title
  
  Inflamm Res
  
  Volume: 70(10-12) Issue: 10-12 Pages: 1101-1111
- DOI
  10.1007/s00011-021-01496-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08277, KAKENHI-PROJECT-19K08278, KAKENHI-PROJECT-19H03408
[Journal Article] Perineural high-mobility group box 1 induces mechanical hypersensitivity through activation of spinal microglia: involvement of glutamate-NMDA receptor dependent mechanism in spinal dorsal horn.2021
- Author(s)
  Nakamura Y, Fukuta A, Miyashita K, Zhang FF, Wang D, Liu K, Wake H, Hisaoka-Nakashima K, Nishibori M, Morioka N
- Journal Title
  
  Biochem Pharmacol
  
  Volume: 186 Pages: 114496-114496
- DOI
  10.1016/j.bcp.2021.114496
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07291, KAKENHI-PROJECT-19H03408, KAKENHI-PROJECT-20K18476
[Journal Article] Malnutrition delayed wound healing after tooth extraction by HMGB1-related prolonged inflammation2021
- Author(s)
  Yao Zhang, Hidetaka Ideguchi, Hiroaki Aoyagi, Keisuke Yamashiro, Tadashi Yamamoto, Masahiro Nishibori, Shogo Takashiba
- Journal Title
  
  Int Immunopharmacol
  
  Volume: 96 Pages: 107772-107772
- DOI
  10.1016/j.intimp.2021.107772
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10128, KAKENHI-PROJECT-19H03408, KAKENHI-PROJECT-20K23054
[Journal Article] Pretreatment with High Mobility Group Box-1 Monoclonal Antibody Prevents the Onset of Trigeminal Neuropathy in Mice with a Distal Infraorbital Nerve Chronic Constriction Injury2021
- Author(s)
  Kochi Takahiro、Nakamura Yoki、Ma Simeng、Hisaoka-Nakashima Kazue、Wang Dengli、Liu Keyue、Wake Hidenori、Nishibori Masahiro、Irifune Masahiro、Morioka Norimitsu
- Journal Title
  
  Molecules
  
  Volume: 26 Issue: 7 Pages: 2035-2035
- DOI
  10.3390/molecules26072035
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18476, KAKENHI-PROJECT-19H03408, KAKENHI-PROJECT-21K10139
[Journal Article] Protective effects of anti-HMGB1 monoclonal antibody on lung ischemia reperfusion injury in mice2021
- Author(s)
  Nakata Kentaro、Okazaki Mikio、Shimizu Dai、Suzawa Ken、Shien Kazuhiko、Miyoshi Kentaroh、Otani Shinji、Yamamoto Hiromasa、Sugimoto Seiichiro、Yamane Masaomi、Ousaka Daiki、Ohara Toshiaki、Matsukawa Akihiro、Nishibori Masahiro、Toyooka Shinichi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 573 Pages: 164-170
- DOI
  10.1016/j.bbrc.2021.08.015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09305, KAKENHI-PROJECT-19H03408, KAKENHI-PROJECT-20K09176
[Journal Article] Advanced glycation end products (AGEs) synergistically potentiated the proinflammatory action of lipopolysaccharide (LPS) and high mobility group box-1 (HMGB1) through their direct interactions.2020
- Author(s)
  Watanabe M, Toyomura T, Tomiyama M, Wake H, Liu K, Teshigawara K, Takahashi H, Nishibori M, Mori S.
- Journal Title
  
  Mol Biol Rep.
  
  Volume: 47(9) Issue: 9 Pages: 7153-7159
- DOI
  10.1007/s11033-020-05783-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07401, KAKENHI-PROJECT-18K06807, KAKENHI-PROJECT-18K06905, KAKENHI-PROJECT-18K14969
[Journal Article] Histidine-rich glycoprotein possesses antioxidant activity through self-oxidation and inhibition of hydroxyl radical production via chelating divalent metal ions in Fenton's reaction.2020
- Author(s)
  Wake H, Takahashi Y, Yoshii Y, Gao S, Mori S, Wang D, Teshigawara K, Nishibori M.
- Journal Title
  
  Free Radic Res.
  
  Volume: 54(8-9) Issue: 8-9 Pages: 649-661
- DOI
  10.1080/10715762.2020.1825703
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07401
[Journal Article] A crucial role of HMGB1 in orofacial and widespread pain sensitization following partial infraorbital nerve transection2020
- Author(s)
  Hu Ting-Ting、Yu Jie、Liu Keyue、Du Yu、Qu Feng-Hui、Guo Fang、Yu Li-Na、Nishibori Masahiro、Chen Zhong、Zhang Shi-Hong
- Journal Title
  
  Brain, Behavior, and Immunity
  
  Volume: 88 Pages: 114-124
- DOI
  10.1016/j.bbi.2020.05.020
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03408
[Journal Article] A comparative study of sulphated polysaccharide effects on advanced glycation end-product uptake and scavenger receptor class A level in macrophages.2020
- Author(s)
  Nishinaka T, Mori S, Yamazaki Y, Niwa A, Wake H, Yoshino T, Nishibori M, Takahashi H.
- Journal Title
  
  Diab Vasc Dis Res.
  
  Volume: 17 Issue: 1 Pages: 147916411989697-147916411989697
- DOI
  10.1177/1479164119896975
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06905, KAKENHI-PROJECT-18K15035
[Journal Article] HMGB1 Translocation in Neurons after Ischemic Insult: Subcellular Localization in Mitochondria and Peroxisomes2020
- Author(s)
  Wang Dengli、Liu Keyue、Fukuyasu Yusuke、Teshigawara Kiyoshi、Fu Li、Wake Hidenori、Ohtsuka Aiji、Nishibori Masahiro
- Journal Title
  
  Cells
  
  Volume: 9 Issue: 3 Pages: 643-643
- DOI
  10.3390/cells9030643
- NAID
  120006860110
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07401
[Journal Article] Histidine-Rich Glycoprotein Inhibits High-Mobility Group Box-1-Mediated Pathways in Vascular Endothelial Cells through CLEC-1A2020
- Author(s)
  Gao Shangze、Wake Hidenori、Sakaguchi Masakiyo、Wang Dengli、Takahashi Youhei、Teshigawara Kiyoshi、Zhong Hui、Mori Shuji、Liu Keyue、Takahashi Hideo、Nishibori Masahiro
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 6 Pages: 101180-101180
- DOI
  10.1016/j.isci.2020.101180
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17930, KAKENHI-PROJECT-19H03408, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-18K06905, KAKENHI-PROJECT-16H06277
[Journal Article] Cav3.2 overexpression in L4 dorsal root ganglion neurons after L5 spinal nerve cutting involves Egr-1, USP5 and HMGB1 in rats: An emerging signaling pathway for neuropathic pain2020
- Author(s)
  Tomita Shiori、Sekiguchi Fumiko、Kasanami Yoshihito、Naoe Katsuki、Tsubota Maho、Wake Hidenori、Nishibori Masahiro、Kawabata Atsufumi
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 888 Pages: 173587-173587
- DOI
  10.1016/j.ejphar.2020.173587
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03408
[Journal Article] An Evaluation of the Activity of Histidine-Rich Glycoprotein on Differentiated Neutrophil-Like Cells from Human Cell Lines.2020
- Author(s)
  Yoshii Y, Wake H, Nishimura Y, Teshigawara K, Wang D, Nishibori M.
- Journal Title
  
  J Pharmacol Exp Ther.
  
  Volume: 375(3) Issue: 3 Pages: 406-413
- DOI
  10.1124/jpet.120.000182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07401
[Journal Article] Cystitis-Related Bladder Pain Involves ATP-Dependent HMGB1 Release from Macrophages and Its Downstream H2S/Cav3.2 Signaling in Mice2020
- Author(s)
  Hiramoto Shiori、Tsubota Maho、Yamaguchi Kaoru、Okazaki Kyoko、Sakaegi Aya、Toriyama Yuki、Tanaka Junichi、Sekiguchi Fumiko、Ishikura Hiroyasu、Wake Hidenori、Nishibori Masahiro、Nguyen Huy Du、Okada Takuya、Toyooka Naoki、Kawabata Atsufumi
- Journal Title
  
  Cells
  
  Volume: 9 Issue: 8 Pages: 1748-1748
- DOI
  10.3390/cells9081748
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03408
[Journal Article] High Mobility Group Box-1 and Blood Brain Barrier Disruption2020
- Author(s)
  Nishibori Masahiro、Wang Dengli、Ousaka Daiki、Wake Hidenori
- Journal Title
  
  Cells
  
  Volume: 9 Issue: 12 Pages: 2650-2650
- DOI
  10.3390/cells9122650
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17930, KAKENHI-PROJECT-19H03408
[Journal Article] The heterodimer S100A8/A9 is a potent therapeutic target for idiopathic pulmonary fibrosis2020
- Author(s)
  Araki Kota、Kinoshita Rie、Tomonobu Nahoko、Gohara Yuma、Tomida Shuta、Takahashi Yuta、Senoo Satoru、Taniguchi Akihiko、Itano Junko、Yamamoto Ken-ichi、Murata Hitoshi、Suzawa Ken、Shien K、Yamamoto H、Okazaki M、Sugimoto S、Ichimura K、Nishibori M、Miyahara N、Toyooka S、Sakaguchi Masakiyo
- Journal Title
  
  Journal of Molecular Medicine
  
  Volume: 99 Issue: 1 Pages: 131-145
- DOI
  10.1007/s00109-020-02001-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07369, KAKENHI-PROJECT-19H03746, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-16H06277
[Journal Article] Corticosterone Induces HMGB1 Release in Primary Cultured Rat Cortical Astrocytes: Involvement of Pannexin-1 and P2X7 Receptor-Dependent Mechanisms2020
- Author(s)
  Hisaoka-Nakashima Kazue、Azuma Honami、Ishikawa Fumina、Nakamura Yoki、Wang Dengli、Liu Keyue、Wake Hidenori、Nishibori Masahiro、Nakata Yoshihiro、Morioka Norimitsu
- Journal Title
  
  Cells
  
  Volume: 9 Issue: 5 Pages: 1068-1068
- DOI
  10.3390/cells9051068
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17930, KAKENHI-PROJECT-19H03408
[Journal Article] High Mobility Group Box 1 Expression in Oral Inflammation and Regeneration2020
- Author(s)
  Keisuke Yamashiro, Hidetaka Ideguchi, Hiroaki Aoyagi, Chiaki Yoshihara-Hirata, Anna Hirai, Risa Suzuki-Kyoshima, Yao Zhang, Hidenori Wake, Masahiro Nishibori, Tadashi Yamamoto, ShogoTakashiba
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 11 Pages: 1461-1461
- DOI
  10.3389/fimmu.2020.01461
- NAID
  120006880201
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10128, KAKENHI-PROJECT-20K23054
[Journal Article] HMGB1 is a therapeutic target and biomarker in diazepam-refractory status epilepticus with wide time window.2019
- Author(s)
  Zhao J, Zheng Y, Liu K, Chen J, Lai N, Fei F, Shi J, Xu C, Wang S, Nishibori M, Wang Y, Chen Z.
- Journal Title
  
  Neurotherapeutics
  
  Volume: in press Issue: 2 Pages: 710-721
- DOI
  10.1007/s13311-019-00815-3
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03408
[Journal Article] Anti-HMGB1 monoclonal antibody therapy for a wide range of CNS and PNS diseases2019
- Author(s)
  Nishibori M, Mori S, Takahashi HK
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 140 Issue: 1 Pages: 94-101
- DOI
  10.1016/j.jphs.2019.04.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06905
[Journal Article] Spinal high-mobility group box-1 induces long-lasting mechanical hypersensitivity through the toll-like receptor 4 and upregulation of interleukin-1β in activated astrocytes.2019
- Author(s)
  Morioka N, Miyauchi K, Miyashita K, Kochi T, Zhang FF, Nakamura Y, Liu K, Wake H, Hisaoka-Nakashima K, Nishibori M, Nakata Y.
- Journal Title
  
  J Neurochem
  
  Volume: 150 Issue: 6 Pages: 738-58
- DOI
  10.1111/jnc.14812
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03408
[Journal Article] Role of non-macrophage cell-derived HMGB1 in oxaliplatin-induced peripheral neuropathy and its prevention by the thrombin/thrombomodulin system in rodents: negative impact of anticoagulants2019
- Author(s)
  Tsubota Maho、Fukuda Ryotaro、Hayashi Yusuke、Miyazaki Takaya、Ueda Shin、Yamashita Rika、Koike Nene、Sekiguchi Fumiko、Wake Hidenori、Wakatsuki Shuji、Ujiie Yuka、Araki Toshiyuki、Nishibori Masahiro、Kawabata Atsufumi
- Journal Title
  
  Journal of Neuroinflammation
  
  Volume: 16 Issue: 1 Pages: 199-199
- DOI
  10.1186/s12974-019-1581-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06710, KAKENHI-PROJECT-19H03408, KAKENHI-PROJECT-17K09046, KAKENHI-PROJECT-17K19945, KAKENHI-PROJECT-16H06276
[Journal Article] The Role of High Mobility Group Box-1 in Epileptogenesis2019
- Author(s)
  Fu L, Nishibori M.
- Journal Title
  
  Acta Medica Okayama
  
  Volume: 73 Issue: 5 Pages: 383-386
- DOI
  10.18926/AMO/57367
- NAID
  120006732620
- URL
  https://ousar.lib.okayama-u.ac.jp/57367
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03408
[Journal Article] Histidine‐rich glycoprotein augments natural killer cell function by modulating PD‐1 expression via CLEC‐1B2019
- Author(s)
  Nishimura Yoshito、Wake Hidenori、Teshigawara Kiyoshi、Wang Dengli、Sakaguchi Masakiyo、Otsuka Fumio、Nishibori Masahiro
- Journal Title
  
  Pharmacology Research & Perspectives
  
  Volume: 7 Issue: 3
- DOI
  10.1002/prp2.481
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07401, KAKENHI-PROJECT-17H03577
[Journal Article] Differential contribution of possible pattern‐recognition receptors to advanced glycation end product?induced cellular responses in macrophage‐like RAW264.7 cells2019
- Author(s)
  Watanabe Masahiro、Toyomura Takao、Wake Hidenori、Liu Keyue、Teshigawara Kiyoshi、Takahashi Hideo、Nishibori Masahiro、Mori Shuji
- Journal Title
  
  Biotechnology and Applied Biochemistry
  
  Volume: in press Issue: 2 Pages: 265-272
- DOI
  10.1002/bab.1843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07401, KAKENHI-PROJECT-18K14969, KAKENHI-PROJECT-18K06807
[Journal Article] Histidine-rich glycoprotein ameliorates endothelial barrier dysfunction through regulation of NF-κB and MAPK signal pathway2019
- Author(s)
  Gao S, Wake H, Gao Y, Wang D, Mori S, Liu K, Teshigawara K, Takahashi H, Nishibori M
- Journal Title
  
  Br J Pharmacol.
  
  Volume: 176 Issue: 15 Pages: 2808-2824
- DOI
  10.1111/bph.14711
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06905, KAKENHI-PROJECT-19K07401, KAKENHI-PROJECT-17K15580
[Journal Article] Evidence of a role for spinal HMGB1 in ischemic stress-induced mechanical allodynia in mice.2018
- Author(s)
  Matsuura W, Harada S, Liu K, Nishibori M, Tokuyama S.
- Journal Title
  
  Brain Res
  
  Volume: 15;1689 Pages: 1-10
- DOI
  10.1016/j.brainres.2018.02.026
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08909, KAKENHI-PROJECT-16K10988
[Journal Article] Histidine-Rich Glycoprotein Suppresses Hyperinflammatory Responses of Lung in a Severe Acute Pancreatitis Mouse Model2018
- Author(s)
  Terao K, Wake H, Adachi N, Liu K, Teshigawara K, Takahashi H, Mori S, Nishibori M
- Journal Title
  
  Pancreas
  
  Volume: 47 Issue: 9 Pages: 1156-1164
- DOI
  10.1097/mpa.0000000000001153
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06905, KAKENHI-PROJECT-17K15580, KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-16K08909
[Journal Article] Anti-HMGB1 Neutralizing Antibody Attenuates Periodontal Inflammation and Bone Resorption in a Murine Periodontitis Model2018
- Author(s)
  Yoshihara-Hirata Chiaki、Yamashiro Keisuke、Yamamoto Tadashi、Aoyagi Hiroaki、Ideguchi Hidetaka、Kawamura Mari、Suzuki Risa、Ono Mitsuaki、Wake Hidenori、Nishibori Masahiro、Takashiba Shogo
- Journal Title
  
  Infection and Immunity
  
  Volume: 86 Issue: 5
- DOI
  10.1128/iai.00111-18
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06994, KAKENHI-PROJECT-16K20670, KAKENHI-PROJECT-18K17050, KAKENHI-PROJECT-16K11624
[Journal Article] Effects of Scavenger Receptor-1 Class A Stimulation on Macrophage Morphology and Highly Modified Advanced Glycation End Product-Protein Phagocytosis.2018
- Author(s)
  Hamasaki S, Kobori T, Yamazaki Y, Kitaura A, Niwa A, Nishinaka T, Nishibori M, Mori S, Nakao S, Takahashi H
- Journal Title
  
  Scientific Reports
  
  Volume: ｓ Issue: 1 Pages: 5901-5901
- DOI
  10.1038/s41598-018-24325-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01881, KAKENHI-PROJECT-17K16766, KAKENHI-PROJECT-18K06905, KAKENHI-PROJECT-18K15035
[Journal Article] Interleukin-18 Amplifies Macrophage Polarization and Morphological Alteration, Leading to Excessive Angiogenesis.2018
- Author(s)
  Kobori T, Hamasaki S, Kitaura A, Yamazaki Y, Nishinaka T, Niwa A, Nakao S, Wake H, Mori S, Yoshino T, Nishibori M, Takahashi H
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 9 Pages: 334-334
- DOI
  10.3389/fimmu.2018.00334
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01881, KAKENHI-PROJECT-15H04686, KAKENHI-PROJECT-17H07272, KAKENHI-PROJECT-15K08253, KAKENHI-PROJECT-15K18996, KAKENHI-PROJECT-18K15035
[Journal Article] Decrease in histidine-rich glycoprotein as a novel biomarker to predict sepsis amongsystemic inflammatory response syndrome.2018
- Author(s)
  Kuroda K, Wake H, Mori S, Hinotsu S, Nishibori M, Morimatsu H.
- Journal Title
  
  Critical Care Medicine
  
  Volume: 46 Issue: 4 Pages: 570-576
- DOI
  10.1097/ccm.0000000000002947
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04686
[Journal Article] Effects of Histidine-rich glycoprotein on erythrocyte aggregation and hemolysis: Implications for a role under septic conditions.2018
- Author(s)
  Zhong H, Wake H, Liu K, Gao Y, Teshigawara K, Sakaguchi M, Mori S, Nishibori M.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 136(3) Issue: 3 Pages: 97-106
- DOI
  10.1016/j.jphs.2017.11.003
- NAID
  130007902144
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-15H04686, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-17K15580
[Journal Article] Inter-α inhibitor proteins maintain neutrophils in a resting state by regulating shape and reducing ROS production.2018
- Author(s)
  Htwe SS, Wake H, Liu K, Teshigawara K, Stonestreet BS, Lim YP, Nishibori M.
- Journal Title
  
  Blood Adv.
  
  Volume: 2(15) Issue: 15 Pages: 1923-1934
- DOI
  10.1182/bloodadvances.2018018986
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-16K08909
[Journal Article] The C‐terminal region of tumor necrosis factor like weak inducer of apoptosis is required for interaction with advanced glycation end products2018
- Author(s)
  Watanabe Masahiro、Toyomura Takao、Wake Hidenori、Liu Keyue、Teshigawara Kiyoshi、Takahashi Hideo、Nishibori Masahiro、Mori Shuji
- Journal Title
  
  Biotechnology and Applied Biochemistry
  
  Volume: 66 Issue: 2 Pages: 254-260
- DOI
  10.1002/bab.1706
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14969, KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-16K08909, KAKENHI-PROJECT-18K06807
[Journal Article] HMGB1-induced inflammatory response promotes bone healing in murine tooth extraction socket2018
- Author(s)
  Aoyagi Hiroaki、Yamashiro Keisuke、Hirata-Yoshihara Chiaki、Ideguchi Hidetaka、Yamasaki Mutsuyo、Kawamura Mari、Yamamoto Tadashi、Kochi Shinsuke、Wake Hidenori、Nishibori Masahiro、Takashiba Shogo
- Journal Title
  
  Journal of Cellular Biochemistry
  
  Volume: - Issue: 7 Pages: 5481-5490
- DOI
  10.1002/jcb.26710
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06994, KAKENHI-PROJECT-16K20670, KAKENHI-PROJECT-18K17050
[Journal Article] Prior Treatment with Anti-High Mobility Group Box-1 Antibody Boosts Human Neural Stem Cell Transplantation-Mediated Functional Recovery After Spinal Cord Injury.2018
- Author(s)
  Uezono N, Zhu Y, Y, Matsuda T,Nakajo M, Abematsu M, Setoguchi T, Mori S, Takahashi HK, Komiya S, Nishibori M, Nakashima K:
- Journal Title
  
  Stem Cells
  
  Volume: - Issue: 5 Pages: 0-0
- DOI
  10.1002/stem.2802
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-INTERNATIONAL-16K21734, KAKENHI-ORGANIZER-16H06524, KAKENHI-PROJECT-15K10411, KAKENHI-PROJECT-18K06905, KAKENHI-PROJECT-18K14820, KAKENHI-PLANNED-16H06527
[Journal Article] Anti-High Mobility Group Box 1 Antibody Therapy May Prevent Cognitive Dysfunction After Traumatic Brain Injury2018
- Author(s)
  Okuma Y, Wake H, Teshigawara K, Takahashi Y, Hishikawa T, Yasuhara T, Mori S, Takahashi HK, Date I, Nishibori M
- Journal Title
  
  World neurosurgery
  
  Volume: 122 Pages: 119-123
- DOI
  10.1016/j.wneu.2018.10.164
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06905, KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-19K09508, KAKENHI-PROJECT-19K09528, KAKENHI-PROJECT-17H04303
[Journal Article] The specific localization of advanced glycation end-products (AGEs) in rat pancreatic islets.2017
- Author(s)
  Morioka Y, Teshigawara K, Tomono Y, Wang D, Izushi Y, Wake H, Liu K, Takahashi HK, Mori S, Nishibori M.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 134(4) Issue: 4 Pages: 218-224
- DOI
  10.1016/j.jphs.2017.07.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-16K08909, KAKENHI-PROJECT-15H04686, KAKENHI-PROJECT-15K08253, KAKENHI-PROJECT-15K08605
[Journal Article] Anti-high Mobility Group Box 1 Antibody Ameliorates Albuminuria in MRL/lpr Lupus-Prone Mice.2017
- Author(s)
  Watanabe H, Watanabe KS, Liu K, Hiramatsu S, Zeggar S, Katsuyama E, Tatebe N, Akahoshi A, Takenaka F, Hanada T, Akehi M, Sasaki T, Sada KE, Matsuura E, Nishibori M, Wada J.
- Journal Title
  
  Molecular Therapy - Methods & Clinical Development
  
  Volume: 6 Pages: 31-39
- DOI
  10.1016/j.omtm.2017.05.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08909, KAKENHI-PROJECT-16K19600
[Journal Article] Macrophage-derived HMGB1 as a Pain Mediator in the Early Stage of Acute Pancreatitis in Mice: Targeting RAGE and CXCL12/CXCR4 Axis.2017
- Author(s)
  Irie Y, Tsubota M, Ishikura H, Sekiguchi F, Terada Y, Tsujiuchi T, Liu K, Nishibori M, Kawabata A.
- Journal Title
  
  Journal of Neuroimmune Pharmacology
  
  Volume: 12 Issue: 4 Pages: 693-707
- DOI
  10.1007/s11481-017-9757-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08909
[Journal Article] Anti-high mobility group box-1 (HMGB1) antibody inhibits hemorrhage-induced brain injury and improved neurological deficits in rats.2017
- Author(s)
  Wang D, Liu K, Wake H, Teshigawara K, Mori S, Nishibori M.
- Journal Title
  
  Sci Rep.
  
  Volume: 7:46243. Issue: 1 Pages: 46243-46243
- DOI
  10.1038/srep46243
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-16K08909
[Journal Article] Advanced glycation end products attenuate the function of tumor necrosis factor-like weak inducer of apoptosis to regulate the inflammatory response2017
- Author(s)
  Watanabe M, Toyomura T, Wake H, Liu K, Teshigawara K, Takahashi H, Nishibori M, Mori S
- Journal Title
  
  Molecular and Cellular Biochemistry
  
  Volume: 印刷中 Issue: 1-2 Pages: 153-162
- DOI
  10.1007/s11010-017-3045-6
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H06785, KAKENHI-PROJECT-15K08605, KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-16K08909, KAKENHI-PROJECT-15K08253
[Journal Article] Therapeutic effects of anti-HMGB1 monoclonal antibody on pilocarpine-induced status epilepticus in mice.2017
- Author(s)
  Fu L, Liu K, Wake H, Teshigawara K, Yoshino T, Takahashi H, Mori S, Nishibori M.
- Journal Title
  
  Sci Rep.
  
  Volume: 7(1):1179. Issue: 1 Pages: 1179-1179
- DOI
  10.1038/s41598-017-01325-y
- NAID
  130007901378
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-16K08909, KAKENHI-PROJECT-15K08253
[Journal Article] Phagocytosis of Advanced Glycation End Products (AGEs) in Macrophages Induces Cell Apoptosis.2017
- Author(s)
  Gao Y, Wake H, Morioka Y, Liu K, Teshigawara K, Shibuya M, Zhou J, Mori S, Takahashi H, Nishibori M.
- Journal Title
  
  Oxid Med Cell Longev.
  
  Volume: 2017:8419035 Issue: 1 Pages: 8419035-8419035
- DOI
  10.1155/2017/8419035
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-16K08909, KAKENHI-PROJECT-15H04686, KAKENHI-PROJECT-15K08253, KAKENHI-PROJECT-15K08605
[Journal Article] Metformin Directly Binds the Alarmin HMGB1 and Inhibits its Proinflammatory Activity.2017
- Author(s)
  Horiuchi T, Sakata N, Narumi Y, Kimura T, Hayashi T, Nagano K, Liu K, Nishibori M, Tsukita S, Yamada T, Katagiri H, Shirakawa R, Horiuchi H.
- Journal Title
  
  J Biol Chem.
  
  Volume: 印刷中 Issue: 20 Pages: 8436-8446
- DOI
  10.1074/jbc.m116.769380
- NAID
  120006331939
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K19000, KAKENHI-PROJECT-16K08909, KAKENHI-PROJECT-26293215, KAKENHI-PROJECT-17H01565, KAKENHI-PROJECT-16K15486
[Journal Article] Therapeutic potential of an anti-high mobility group box-1 monoclonal antibody in epilepsy.2017
- Author(s)
  Zhao J, Wang Y, Xu C, Liu K, Wang Y, Chen L, Wu X, Gao F, Guo Y, Zhu J, Wang S, Nishibori M, Chen Z.
- Journal Title
  
  Brain Behavior and Immunity
  
  Volume: 64 Pages: 308-319
- DOI
  10.1016/j.bbi.2017.02.002
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08909
[Journal Article] Anti-high mobility group box 1 monoclonal antibody improves ischemia/reperfusion injury and mode of liver regeneration after partial hepatectomy.2016
- Author(s)
  Sugihara M, Sadamori H, Nishibori M, Sato Y, Tazawa H, Shinoura S, Umeda Y, Yoshida R, Nobuoka D, Utsumi M, Ohno K, Nagasaka T, Yoshino T, Takahashi HK, Yagi T, Fujiwara T.
- Journal Title
  
  American Journal of Surgery
  
  Volume: 211 Issue: 1 Pages: 179-188
- DOI
  10.1016/j.amjsurg.2015.06.025
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08253, KAKENHI-PROJECT-15H03034
[Journal Article] HMGB1 Translocation After Ischemia in the Ovine Fetal Brain.2016
- Author(s)
  Zhang J, Klufas D, Manalo K, Adjepong K, Davidson JO, Wassink G, Bennet L, Gunn AJ, Stopa EG, Liu K, Nishibori M, Stonestreet BS.
- Journal Title
  
  J Neuropathol Exp Neurol.
  
  Volume: 75(6) Issue: 6 Pages: 527-538
- DOI
  10.1093/jnen/nlw030
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08909
[Journal Article] Histidine-rich glycoprotein prevents septic lethality through regulation of immunothrombosis and inflammation.2016
- Author(s)
  Wake H, Mori S, Liu K, Morioka Y, Teshigawara K, Sakaguchi M, Kuroda K, Gao Y, Takahashi H, Ohtsuka A, Yoshino T, Morimatsu H, Nishibori M.
- Journal Title
  
  EBioMedicine
  
  Volume: 9 Pages: 180-194
- DOI
  10.1016/j.ebiom.2016.06.003
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04686, KAKENHI-PROJECT-26290039, KAKENHI-PROJECT-15K14382, KAKENHI-PROJECT-15K08253, KAKENHI-PROJECT-16K08232
[Journal Article] Soluble form of the receptor for advanced glycation end-products attenuates inflammatory pathogenesis in a rat model of lipopolysaccharide-induced lung injury.2016
- Author(s)
  Izushi Y, Teshigawara K, Liu K, Wang D, Wake H, Takata K, Yoshino T, Takahashi HK, Mori S, Nishibori M.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: S1347-8613(16)00026-8. Issue: 4 Pages: 1-9
- DOI
  10.1016/j.jphs.2016.02.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460649, KAKENHI-PROJECT-15K08253, KAKENHI-PROJECT-16K08232
[Journal Article] Possible involvement of the HMGB1/RAGE signaling mechanism in the induction of central post-stroke pain induced by acute global cerebral ischemia.2016
- Author(s)
  Harada S, Matsuura W, Liu K, Nishibori M, Tokuyama S.
- Journal Title
  
  Brain Res.
  
  Volume: 1646 Pages: 433-440
- DOI
  10.1016/j.brainres.2016.06.028
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K08909, KAKENHI-PROJECT-16K10988
[Journal Article] Peripheral HMGB1-induced hyperalgesia in mice: redox state-dependent distinct roles of RAGE and TLR42016
- Author(s)
  Yamasoba, D., Tsubota, M., Domoto, R., Sekiguchi, F., Nishikawa, H., Liu, K., Nishibori, M., Ishikura, H., Yamamoto, T., Taga, A., Kawabata, A.
- Journal Title
  
  J. Pharmacol. Sci.
  
  Volume: 130 Issue: 2 Pages: 139-142
- DOI
  10.1016/j.jphs.2016.01.005
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460710, KAKENHI-PROJECT-16K08909
[Journal Article] Anti-high mobility group box-1 (HMGB1) antibody attenuates delayed cerebral vasospasm and brain injury after subarachnoid hemorrhage in rats2016
- Author(s)
  Haruma J, Teshigawara K, Hishikawa T, Wang D, Liu K, Wake H, Mori S, Takahashi HK, Sugiu K, Date I, Nishibori M.
- Journal Title
  
  Scientific reports
  
  Volume: 6 Issue: 1 Pages: 37755-37768
- DOI
  10.1038/srep37755
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08253, KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-16K08909
[Journal Article] Involvement of high mobility group box 1 in the development and maintenance of chemotherapy-induced peripheral neuropathy in rats2016
- Author(s)
  Nishida, T., Tsubota, M., Kawaishi, Y., Yamanishi, H., Kawakami, N., Sekiguchi, F., Ishikura, H., Liu, K., Nishibori, M., Kawabata, A.
- Journal Title
  
  Toxocology
  
  Volume: 365 Pages: 48-58
- DOI
  10.1016/j.tox.2016.07.016
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460710, KAKENHI-PROJECT-16K08909
[Journal Article] Anti-HMGB1 antibody reduces weight gain in mice fed a high-fat diet.2015
- Author(s)
  Montes VN, Subramanian S, Goodspeed L, Wang SA, Omer M, Bobik A, Teshigawara K, Nishibori M, Chait A.
- Journal Title
  
  Nutr Diabetes.
  
  Volume: 5, e161 Issue: 6 Pages: e161-e161
- DOI
  10.1038/nutd.2015.11
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460649
[Journal Article] Voluntary exercise induces neurogenesis in the hypothalamus and ependymal lining of the third ventricle.2015
- Author(s)
  Niwa A, Nishibori M, Hamasaki S, Kobori T, Liu K, Wake H, Mori S, Yoshino T, Takahashi H.
- Journal Title
  
  Brain Structure & Function
  
  Volume: 印刷中 Issue: 3 Pages: 1863-2653
- DOI
  10.1007/s00429-015-0995-x
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390061, KAKENHI-PROJECT-24590658, KAKENHI-PROJECT-15K08253, KAKENHI-PROJECT-26350918
[Journal Article] Glycyrrhizin inhibits traumatic brain injury by reducing HMGB1-RAGE interaction.2014
- Author(s)
  Okuma Y, Liu K, Wake H, Liu R, Nishimura Y, Hui Z, Teshigawara K, Haruma J, Yamamoto Y, Yamamoto H, Date I, Takahashi HK, Mori S, Nishibori M.
- Journal Title
  
  Neuropharmacology
  
  Volume: 85 Pages: 18-26
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590337
[Journal Article] Glycyrrhizin inhibits traumatic brain injury by reducing HMGB1-RAGE interaction.2014
- Author(s)
  OkumaY, Liu K, Wake H, Liu R, Nishimura Y, Zhong H, Teshigawara K, Haruma J, Yamamoto Y, Yamamoto H, Date I, Takahashi HK, Mori S, Nishibori M.
- Journal Title
  
  Neuropharmacology
  
  Volume: 85 Pages: 18-26
- DOI
  10.1016/j.neuropharm.2014.05.007
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390061, KAKENHI-PROJECT-24590375, KAKENHI-PROJECT-24590658, KAKENHI-PROJECT-25460649, KAKENHI-PROJECT-25461335, KAKENHI-PROJECT-25670464, KAKENHI-PROJECT-26293323
[Journal Article] Does HMGB1 predict occult neck lymph node metastasis in early tongue carcinoma? A case-control study of 26 patients.2014
- Author(s)
  Hanakawa H, Orita Y, Sato Y, Takeuchi M, Takao S, Ohno K, Kohno T, Iwaki N, Marunaka H, Tamamura R, Nishibori M, Nagatsuka H, Nishizaki K, Yoshino T.
- Journal Title
  
  J Laryngol Otol.
  
  Volume: 128 Issue: 10 Pages: 926-931
- DOI
  10.1017/s0022215114001819
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390061, KAKENHI-PROJECT-24592766
[Journal Article] 抗HMGB1抗体治療の可能性-外傷性脳障害と神経因性疼痛に対する抗HMGB1抗体治療2014
- Author(s)
  大熊佑, 伊達勲, 西堀正洋
- Journal Title
  
  日薬理誌
  
  Volume: 143 Pages: 5-9
- NAID
  130004827691
- Data Source
  KAKENHI-PROJECT-24390061
[Journal Article] Usefulness of high mobility group box 1 protein as a plasma biomarker in patient with peripheral artery disease.2014
- Author(s)
  Oozawa S, Sano S, Nishibori M.
- Journal Title
  
  Acta Med. Okayama
  
  Volume: 68(3) Pages: 157-162
- NAID
  120005447128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670464
[Journal Article] Suppression of peritoneal thickening by histamine in a mouse model of peritoneal scraping2014
- Author(s)
  Liu K, Yorozuya T, Adachi N, Motoki A, Ninomiya K, Mabuchi H, Iwamoto N, Nishibori M
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: 19 Issue: 4 Pages: 1342-1751
- DOI
  10.1007/s10157-014-1027-5
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590658
[Journal Article] Usefulness of high mobility group box 1 protein as a plasma biomarker in patient with peripheral artery disease.2014
- Author(s)
  Oozawa S, Sano S, Nishibori M.
- Journal Title
  
  Acta Med. Okayama
  
  Volume: 68(3) Pages: 157-162
- NAID
  120005447128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390061
[Journal Article] 抗HMGB1抗体治療の可能性-外傷性脳障害と神経因性疼痛に対する抗HMGB1抗体治療2014
- Author(s)
  大熊佑, 伊達勲, 西堀正洋
- Journal Title
  
  日薬理誌
  
  Volume: 143 Pages: 5-9
- NAID
  130004827691
- Data Source
  KAKENHI-PROJECT-25670464
[Journal Article] DAMPs：HMGB1の脳神経障害作用2013
- Author(s)
  西堀正洋
- Journal Title
  
  Thrombosis Medicine
  
  Volume: 3(4) Pages: 5-11
- Data Source
  KAKENHI-PROJECT-25670464
[Journal Article] Neuropathic pain in rats with a partial sciatic nerve ligation is alleviated by intravenous injection of monoclonal antibody to high mobility group box-1.2013
- Author(s)
  Nakamura Y, Morioka N, Abe H, Zhang FF, Nakashima KH, Liu K, Nishibori M, Nakata Y.
- Journal Title
  
  PLOS ONE
  
  Volume: 8(8) Issue: 8 Pages: e73640-e73640
- DOI
  10.1371/journal.pone.0073640
- NAID
  120005702487
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390061
[Journal Article] DAMPs：HMGB1の脳神経障害作用2013
- Author(s)
  西堀正洋
- Journal Title
  
  Thrombosis Medicine
  
  Volume: 3(4) Pages: 5-11
- Data Source
  KAKENHI-PROJECT-24390061
[Journal Article] Histamine inhibits high mobility group box 1-induced adhesion molecule expression on human monocytes2013
- Author(s)
  Takahashi H、Sadamori H、Teshigawara K、Niwa A、Liu K、Wake H、Mori S、Yoshino T、Nishibori M
- Journal Title
  
  Eur J Phamacol
  
  Volume: Vol.718、No.1-3 Issue: 1-3 Pages: 305-313
- DOI
  10.1016/j.ejphar.2013.08.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591864, KAKENHI-PROJECT-23790601, KAKENHI-PROJECT-24390061, KAKENHI-PROJECT-24590337, KAKENHI-PROJECT-24590672, KAKENHI-PROJECT-25460649, KAKENHI-PROJECT-25461947, KAKENHI-PROJECT-25670464
[Journal Article] Role of cell-cell interactions in high mobility group box 1 cytokine activity in human peripheral blood mononuclear cells and mouse splenocytes2013
- Author(s)
  Takahashi HK,Sadamori H, Liu K, Wake H, Mori S, Yoshino T, Yamamoto Y, Yamamoto H,Nishibori M.
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 701 Pages: 194-202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590337
[Journal Article] Mannitol enhances therapeutic effects of intra-arterial transplantation of mesenchymal stem cells into the brain after traumatic brain injury2013
- Author(s)
  Okuma Y, Wang F, Toyoshima A, Kameda M, Hishikawa T, Tokunaga K, Sugiu K, Liu K, Haruma J, Nishibori M, Yasuhara T, Date I
- Journal Title
  
  Neurosci Letters
  
  Volume: 554 Pages: 156-161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590658
[Journal Article] Histamine inhibits high mobility group box 1-induced adhesion molecule expression on human monocytes2013
- Author(s)
  Takahashi H1, Sadamori H, Teshigawara K, Niwa A, Liu K, Wake H, Mori S, Yoshino T, Nishibori M
- Journal Title
  
  EuropeanJournalofPharmacology
  
  Volume: 718(1-3) Pages: 305-313
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590658
[Journal Article] Neuropathic pain in rats with a partial sciatic nerve ligation is alleviated by intravenous injection of monoclonal antibody to high mobility group box-12013
- Author(s)
  Nakamura Y1, Morioka N, Abe H, Zhang FF, Hisaoka-Nakashima K, Liu K, Nishibori M, Nakata Y
- Journal Title
  
  PLoS One
  
  Volume: 8(8)
- NAID
  120005702487
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590658
[Journal Article] Mannitol enhances therapeutic effects of intra-arterial transplantation of mesenchymal stem cells into the brain after traumatic brain injury2013
- Author(s)
  Okuma Y, Wang F, Toyoshima A, Kameda M, Hishikawa T, Tokunaga K, Sugiu K, Liu K, Haruma J, Nishibori M, Yasuhara T, Date I
- Journal Title
  
  Neurosci Lett
  
  Volume: 554 Pages: 156-61
- DOI
  10.1016/j.neulet.2013.08.058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390349, KAKENHI-PROJECT-23791602, KAKENHI-PROJECT-24390061, KAKENHI-PROJECT-25860912, KAKENHI-PROJECT-25861277
[Journal Article] Role of cell-cell interactions in high mobility group box 1 cytokine activity in human peripheral blood mononuclear cells and mouse splenocytes2013
- Author(s)
  Kohka Takahashi H, Sadamori H, Liu K, Wake H, Mori S, Yoshino T, Yamamoto Y, Yamamoto H, Nishibori M
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 701(1-3) Issue: 1-3 Pages: 194-202
- DOI
  10.1016/j.ejphar.2012.11.058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591864, KAKENHI-PROJECT-23659687, KAKENHI-PROJECT-24390061, KAKENHI-PROJECT-24590375, KAKENHI-PROJECT-24590658, KAKENHI-PROJECT-24590672
[Journal Article] Anti-high mobility group box-1 antibody therapy for traumatic brain injury2012
- Author(s)
  Okuma Y, Liu K, Wake H, Zhang J, Maruo T, Date I, Yoshino T, Ohtsuka A, Otani N, Tomura S, Shima K, Yamamoto Y, Yamamoto H, Takahashi H K, Mori S, Nishibori M
- Journal Title
  
  Annals of Neurology
  
  Volume: 72 Issue: 3 Pages: 373-384
- DOI
  10.1002/ana.23602
- NAID
  130004427993
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390349, KAKENHI-PROJECT-23659430, KAKENHI-PROJECT-23659687, KAKENHI-PROJECT-24390061, KAKENHI-PROJECT-24590337, KAKENHI-PROJECT-24590658, KAKENHI-PROJECT-24590672
[Journal Article] Peroxiredoxin family proteins are key initiators of post-ischemic inflammation in the brain2012
- Author(s)
  Shichita T
- Journal Title
  
  Nature Medicine
  
  Volume: 18 Issue: 6 Pages: 911-917
- DOI
  10.1038/nm.2749
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249009, KAKENHI-PROJECT-22590420, KAKENHI-PROJECT-23591262, KAKENHI-PROJECT-23659242, KAKENHI-PROJECT-23659687, KAKENHI-PROJECT-23790545, KAKENHI-PROJECT-23791662, KAKENHI-PROJECT-24390061, KAKENHI-PROJECT-24590337, KAKENHI-PLANNED-21117002, KAKENHI-PUBLICLY-24117718
[Journal Article] Anti-High Mobility Group Box-1 Antibody Therapy for Traumatic Brain Injury2012
- Author(s)
  Okuma Y., Liu K., Wake H., Zhang J., Maruo T., Date I., Yoshio T., Ohtsuka A., Otani N., Tomura S., Shima K., Yamamoto Y., Yamamoto H., Takahashi H., Mori S.,Nishibori M
- Journal Title
  
  Annals of Neurology
  
  Volume: in press
- NAID
  130004427993
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659687
[Journal Article] Peroxiredoxin family proteins are key initiators of post-ischemic inflammation in the brain2012
- Author(s)
  Shichida T., Hasegawa E., Takahashi H., Mori S., Nishibori M. , Kuroda K., Miyake K., Akira S., Yoshimura A. et al.
- Journal Title
  
  Nature Medicine
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659687
[Journal Article] Reduction of the infarct size by simultaneous administration of l-histidine and diphenhydramine in ischaemic rat brains.2011
- Author(s)
  Adachi N, Liu K, Ninomiya K, Matsuoka E, Motoki A, Irisawa Y, Nishibori M
- Journal Title
  
  Resuscitation
  
  Volume: 82(2) Pages: 219-221
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659687
[Journal Article] Anti-high Mobility Group Box-1 Monoclonal Antibody Protects the Blood-Brain Barrier from Ischemia-Induced Disruption in Rats.2011
- Author(s)
  Zhang J, Liu K, Wake H, Nishibori M. et al.(11名、11番目)
- Journal Title
  
  Stroke
  
  Volume: 42(5) Pages: 1420-1428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390071
[Journal Article] Anti-high mobility group box-1 monoclonal antibody protects the blood-brain barrier from ischemia-induced disruption in rats2011
- Author(s)
  Zhang J, Takahashi HK, Liu K, Wake H, Liu R, Maruo T, Date I, Yoshino T, Ohtsuka A, Mori S, Nishibori M
- Journal Title
  
  Stroke
  
  Volume: 42(5) Pages: 1420-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590594
[Journal Article] High-mobility group box protein 1 neutralization reduces development of diet-induced atherosclerosis in apolipoproteine-deficient mice2011
- Author(s)
  Kanellakis P, Agrotis A, Kyaw TS, Koulis C, Ahrens I, Mori S, Takahashi HK, Liu K, Peter K, Nishibori M, Bobik A
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 31(2) Pages: 313-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590594
[Journal Article] High-Mobility Group Box Protein 1 Neutralization Reduces Development of Diet-Induced Atherosclerosis in Apolipoprotein E-Deficient Mice.2011
- Author(s)
  Kanellakis P, Liu K, Nishibori M, et al.(11名、10番目) Bobik A.
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 31(2) Pages: 313-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390071
[Journal Article] Bobik A. High-Mobility Group Box Protein 1 Neutralization Reduces Development of Diet-Induced Atherosclerosis in Apolipoprotein E-Deficient Mice.2011
- Author(s)
  Kanellakis P, Agrotis A, Kyaw TS, Koulis C, Ahrens I, Mori S, Takahashi HK, Liu K, Peter K, Nishibori M
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 32(2) Pages: 313-319
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659687
[Journal Article] Anti-high Mobility Group Box-1 Monoclonal Antibody Protects the Blood-Brain Barrier from Ischemia-Induced Disruption in Rats.2011
- Author(s)
  Zhang J, Takahashi HK, Liu K, Wake K, Liu R, Maruo T, Date I, Yoshino T, Ohtsuka A, Mori S, Nishibori M.
- Journal Title
  
  Stroke
  
  Volume: 42(5) Pages: 1420-1428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659687
[Journal Article] Deleterious Role of Anti-high Mobility Group Box 1 Monoclonal Antibody in Retinal Ischemia- reperfusion Injury.2011
- Author(s)
  Yang H, Hirooka K, Liu Y, Fujita T, Fukuda K, Nakamutra T, Itano T, Zhang J, Nishibori M, Shiraga F
- Journal Title
  
  Current Eye Research
  
  Volume: 36(11) Pages: 1037-1046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659687
[Journal Article] Reduction of the infarct size by simultaneous administration of l-histidine and diphenhydramine in ischaemic rat brains.2011
- Author(s)
  Adachi N, Liu K, Nishibori M., et al.(7名、7番目)
- Journal Title
  
  Resuscitation
  
  Volume: 82(2) Pages: 219-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390071
[Journal Article] Gene Expression and Localization of High-mobility Group Box Chromosomal Protein-1 (HMGB-1) in Human Osteoarthritic Cartilage2011
- Author(s)
  Terada S., Yoshida A., Nasu Y., Mori S.,Tomono Y., Tanaka M., Takahashi H., Nishibori M.,Ozaki T., Nishida K
- Journal Title
  
  Acta Med. Okayama
  
  Volume: 65(6) Pages: 369-377
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659687
[Journal Article] Histamine inhibits adhesion molecule expression in human monocytes, induced by advanced glycation end products, during the mixed lymphocyte reaction.2010
- Author(s)
  Zhang J, Liu K, Wake H, Nishibori M., et al.(11名、11番目)
- Journal Title
  
  Br J Pharmacol
  
  Volume: 160 Pages: 1378-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390071
[Journal Article] Advanced glycation end products enhance monocyte activation during human mixed lymphocyte reaction.2010
- Author(s)
  Ohashi K, Takahashi HK, Mori S, Liu K, Wake H, Sadamori H, Matsuda H, Yagi T, Yoshino T, Nishibori M, Tanaka N
- Journal Title
  
  Clin Immunol 134
  
  Pages: 345-353
- Data Source
  KAKENHI-PROJECT-20590539
[Journal Article] Advanced glycation end products enhance monocyte activation during human mixedlymphocyte reaction2010
- Author(s)
  Ohashi K, Takahashi HK, Mori S, Liu K, Wake H, Sadamori H, Matsuda H, Yagi T, Yoshino T, Nishibori M, Tanaka N
- Journal Title
  
  Clin Immunol
  
  Volume: 134(3) Pages: 345-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590594
[Journal Article] Anti-Sp100 antibody2010
- Author(s)
  Mori S, Wake H, Liu K, Takahashi HK, Nishibori M
- Journal Title
  
  Nihon Rinsho
  
  Volume: 68 Suppl 6 Pages: 711-3
- NAID
  40017181877
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590594
[Journal Article] Histamine inhibits advanced glycation end product-induced adhesion molecule expression on monocytes during human mixed lymphocyte reaction2010
- Author(s)
  Zhang J, Takahashi HK, Liu K, Wake H, Liu R, Sadamori H, Matsuda H, Yagi T , Yoshino T, Mori S, Nishibori M
- Journal Title
  
  Br J Pharmacol. 160
  
  Pages: 1378-1386
- Data Source
  KAKENHI-PROJECT-20590539
[Journal Article] Beta2-adrenoceptor stimulation inhibits advanced glycation end products-induced adhesion molecule expression and cytokine production in human peripheral bloodmononuclear cells2010
- Author(s)
  Takahashi HK, Mori S, Liu K, Wake H, Zhang J, Liu R, Yoshino T, Nishibori M
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 627(1-3) Pages: 313-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590594
[Journal Article] Effect of nicotine on advanced glycation end product-induced immune response in human monocytes2010
- Author(s)
  Takahashi HK, Liu K, Wake H, Nishibori M, et al., (8名、8番目)
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 332 Pages: 1013-1021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390071
[Journal Article] Prostaglandin E2 inhibits advanced glycation end product-induced adhesion molecule expression on monocytes, cytokine production, and lymphocyte proliferation during human mixed lymphocyte reaction.2010
- Author(s)
  Takahashi HK, Liu K, Wake H, Nishibori M., et al.(11名、11番目)
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 334 Pages: 964-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390071
[Journal Article] Advanced glycation end products enhance monocyte activation during human mixed lymphocyte reaction.2010
- Author(s)
  Ohashi K, Liu K, Wake H, Nishibori M, et al., (11名、10番目)
- Journal Title
  
  Clin Immunol
  
  Volume: 134 Pages: 345-353
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390071
[Journal Article] Effect of nicotine on advanced glycation end product-induced immune response in humanmonocytes2010
- Author(s)
  Takahashi HK, Liu K, Wake H, Mori S, Zhang J, Liu R, Yoshino T, Nishibori M
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 332(3) Pages: 1013-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590594
[Journal Article] beta(2)-adrenoceptor stimulation inhibits advanced glycation end products-induced adhesion molecule expression and cytokine production in human peripheral blood mononuclear cells.2010
- Author(s)
  Takahashi HK, Mori S, Liu K, Wake H, Zhang J, Liu R, Yoshino T, Nishibori, M.
- Journal Title
  
  Eur J Pharmacol. 627
  
  Pages: 313-317
- Data Source
  KAKENHI-PROJECT-20590539
[Journal Article] Prostaglandin E2 inhibits advanced glycation end product-induced adhesion molecule expression on monocytes, cytokine production and lymphocyte proliferation during human mixed lymphocyte reaction.2010
- Author(s)
  Takahashi HK, Zhang J, Mori S, Liu K, Wake H, Liu R, Sadamori H, Matsuda H, Yagi T, Yoshino T, Nishibori M
- Journal Title
  
  J Pharmacol Exp Ther. 334
  
  Pages: 964-972
- Data Source
  KAKENHI-PROJECT-20590539
[Journal Article] Effect of nicotine on advanced glycation end products-induced immune response in human monocytes.2010
- Author(s)
  Takahashi HK, Liu K, Wake H, Mori S, Zhang J, Liu R, Yoshino T, Nishibori M.
- Journal Title
  
  J Pharmacol Exp Ther. 332
  
  Pages: 1013-1021
- Data Source
  KAKENHI-PROJECT-20590539
[Journal Article] Prostaglandin E2 inhibits advanced glycation end product induced adhesion molecule expression on monocytes, cytokine production, and lymphocyte proliferation during human mixed lymphocyte reaction2010
- Author(s)
  Takahashi HK, Zhang J, Mori S, Liu K, Wake H, Liu R, Sadamori H, Matsuda H, Yagi T, Yoshino T, Nishibori M
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 34(3) Pages: 964-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590594
[Journal Article] Ciprofloxacin inhibits advanced glycation end products-induced adhesion molecule expression on human monocytes.2010
- Author(s)
  Mori S, Liu K, Wake H, Nishibori M., et al.(8名、8番目)
- Journal Title
  
  Br J Pharmacol
  
  Volume: 161 Pages: 229-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390071
[Journal Article] Advanced glycation end products subspecies-selectively induce adhesion molecule expression and cytokine production in human peripheral blood mononuclear cells.2009
- Author(s)
  Takahashi HK, Mori S, Wake H, Liu K, Yoshino T, Ohashi K, Tanaka N, Shikata K, Makino H, Nishibori M.
- Journal Title
  
  J Pharmacol Exp Ther. 330
  
  Pages: 89-98
- Data Source
  KAKENHI-PROJECT-20590539
[Journal Article] Establishment of in vitro binding assay of high mobility group box-1 and S100A12 to receptor for advanced glycation endproducts : heparin's effect on binding.2009
- Author(s)
  Liu R, Mori S, Wake H, Zhang J, Liu K, Izushi Y, Takahashi HK, Peng B, Nishibori M.
- Journal Title
  
  Acta Med Okayama. 63(4)
  
  Pages: 203-211
- NAID
  120002312782
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590594
[Journal Article] High mobility group box 1 complexed with heparin induced angiogenesis in a matrigel plug assay.2009
- Author(s)
  Wake H, Mori S, Liu K, Takahashi HK, Nishibori M
- Journal Title
  
  Acta Med Okayama 63
  
  Pages: 249-262
- NAID
  120002312983
- Data Source
  KAKENHI-PROJECT-20590539
[Journal Article] Therapeutic effect of anti-nucleokine monoclonal antibody on ischemic brain infarction2009
- Author(s)
  Mori S, Liu K, Takahashi HK, Nishibori M.
- Journal Title
  
  Yakugaku Zasshi 129(1)
  
  Pages: 25-31
- NAID
  110007028557
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590594
[Journal Article] Histamine inhibits advanced glycation end products-induced adhesion molecule expression on human monocytes.2009
- Author(s)
  Wake H, Takahashi HK, Mori S, Liu K, Yoshino T, Nishibori M.
- Journal Title
  
  J Pharmacol Exp Ther 330
  
  Pages: 826-833
- Data Source
  KAKENHI-PROJECT-20590539
[Journal Article] Histamine inhibits advanced glycation end products-induced adhesion molecule expression on human monocytes2009
- Author(s)
  Wake H, Takahashi HK, Mori S, Liu K, Yoshino T, Nishibori M
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 330(3) Pages: 826-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590594
[Journal Article] Establishment of in vitro binding assay of high mobility group box-1 and S100A12 to receptor for advanced glycation endproducts : heparin's effect on binding2009
- Author(s)
  Liu R, Mori S, Wake H, Zhang J, Liu K, Izushi Y, Takahashi HK, Peng B, Nishibori M
- Journal Title
  
  Acta Med Okayama
  
  Volume: 63(4) Pages: 203-11
- NAID
  120002312782
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590594
[Journal Article] Specific removal of monocytes from peripheral blood of septic patients by polymyxin B-immobilized filter column.2009
- Author(s)
  Nishibori M, Takahashi HK, Katayama H, Mori S, Saito S, Iwagaki H, Tanaka N, Morita K, Ohtsuka A
- Journal Title
  
  Acta Med Okayama. 63
  
  Pages: 65-69
- NAID
  120002312427
- Data Source
  KAKENHI-PROJECT-20590539
[Journal Article] Prostaglandin E2 inhibits advanced glycation end product-induced adhesion molecule expression, cytokine production, and lymphocyte proliferation in human peripheral blood mononuclear cells2009
- Author(s)
  Takahashi HK, Liu K, Wake H, Mori S, Zhang J, Liu R, Yoshino T, Nishibori M
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 331(2) Pages: 656-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590594
[Journal Article] Prostaglandins E2 inhibits advanced glycation end products-induced adhesion molecule expression, cytokine production and lymphocyte proliferation in human peripheral blood mononuclear cells2009
- Author(s)
  Takahashi HK, Liu K, Wake H, Nishibori M, et al., (8名、8番目)
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 331 Pages: 656-670
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390071
[Journal Article] Histamine inhibits advanced glycation end products-induced adhesion molecule expression on human monocytes.2009
- Author(s)
  Wake H, Takahashi HK, Liu K, Nishibori M, et al., (6名、6番目)
- Journal Title
  
  J. Pharmacol Exp Ther
  
  Volume: 330 Pages: 826-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390071
[Journal Article] Histidine-rich glycoprotein inhibited high mobility group box 1 in complex with heparin-induced angiogenesis in matrigel plug assay.2009
- Author(s)
  Wake H, Mori S, Liu K, Takahashi HK, Nishibori M
- Journal Title
  
  Eur J Pharmacol. 623
  
  Pages: 89-95
- Data Source
  KAKENHI-PROJECT-20590539
[Journal Article] Establishment of in vitro binding assay of high mobility group box-1 and S100A12 to receptor for advanced glycation endproducts : heparin's effect on binding.2009
- Author(s)
  Liu R, Mori S., Wake H, Zhang J, Liu K, Izushi Y, Takahashi HK, Peng B, Nishibori M
- Journal Title
  
  Acta Med Okayama 63
  
  Pages: 203-211
- NAID
  120002312782
- Data Source
  KAKENHI-PROJECT-20590539
[Journal Article] Histidine-rich glycoprotein inhibited high mobility group box 1 in complex with heparin-induced angiogenesis in matrigel plug assay2009
- Author(s)
  Wake H, Mori S, Liu K, Takahashi HK, Nishibori M
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 623(1-3) Pages: 89-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590594
[Journal Article] Advanced glycation end products subspecies-selectively induce adhesion molecule expression and cytokine production in human peripheral blood mononuclear cells.2009
- Author(s)
  Takahashi HK, Mori S, Wake H, Liu K, Yoshino T, Ohashi K, Tanaka N, Shikata K, Makino H, Nishibori M.
- Journal Title
  
  J Pharmacol Exp Ther 330(1)
  
  Pages: 89-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590594
[Journal Article] Advanced glycation end products subspecies-selectively induce adhesion molecule expression and cytokine production in human peripheral blood mononuclear cells2009
- Author(s)
  Takahashi HK, Mori S, Wake H, Liu K, Yoshino T, Ohashi K, Tanaka N, Shikata K, Makino H, Nishibori M
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 330(1) Pages: 89-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590594
[Journal Article] Prostaglandin E2 inhibits advanced glycation end product-induced adhesion molecule expression, cytokine production, and lymphocyte proliferation in human peripheral blood mononuclear cells.2009
- Author(s)
  Takahashi HK, Liu K, Wake H, Mori S, Zhang J, Liu R, Yoshino T, Nishibori M.
- Journal Title
  
  J Pharmacol Exp Ther. 331
  
  Pages: 656-670
- Data Source
  KAKENHI-PROJECT-20590539
[Journal Article] Therapeutic effect of anti-nucleokine monoclonal antibody on ischemic braininfarction2009
- Author(s)
  Mori S, Liu K, Takahashi HK, Nishibori M
- Journal Title
  
  Yakugaku Zasshi
  
  Volume: 129(1) Pages: 25-31
- NAID
  110007028557
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590594
[Journal Article] Advanced glycation end products subspecies-selectively induce adhesion molecule expression and cytokine production in human peripheral blood mononuclear cells.2009
- Author(s)
  Takahashi HK, Wake H, Liu K, Nishibori M, et al., (10名、10番目)
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 330 Pages: 89-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390071
[Journal Article] High mobility group box 1 complexed with heparin induced angiogenesis in a matrigelplug assay2009
- Author(s)
  Wake H, Mori S, Liu K, Takahashi HK, Nishibori M
- Journal Title
  
  Acta Med Okayama
  
  Volume: 63(5) Pages: 249-62
- NAID
  120002312983
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590594
[Journal Article] Effects of HMGB1 on ischemia reperfusion injury in the rat heart2008
- Author(s)
  Oozawa S, Mori S, Kanke T, Takahashi H, Liu K, Tomono Y, Asanuma M, Miyazaki I, Nishibori M
- Journal Title
  
  Sano S Circ J 72(7)
  
  Pages: 1178-84
- NAID
  110006792076
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590534
[Journal Article] ラット中脳動脈閉塞・再灌流モデルにおける抗HMGB1単クローン抗体の治療効果2008
- Author(s)
  劉克約、森秀治、高橋英夫、西堀正洋
- Journal Title
  
  岡山医学会雑誌第120巻第3号
  
  Pages: 271-277
- NAID
  130004903140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590534
[Journal Article] Inducible histamine protects mice from hepatitis through H2-receptor stimulation2008
- Author(s)
  Mori S, Takahashi HK, Nishibori M
- Journal Title
  
  Yakugaku Zasshi 128(2)
  
  Pages: 247-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590534
[Journal Article] Suppression of ischaemia-induced cytokine release by dimaprit and amelioration of liver injury in rats2008
- Author(s)
  Motoki A, Adachi N, Liu K, Takahashi HK, Nishibori M, Yorozuya T, Arai T, Nagaro T
- Journal Title
  
  Basic Clin Pharmacol Toxicol 102(4)
  
  Pages: 394-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590534
[Journal Article] Stimulation of adenosine A2A receptor inhibits LPS-induced expression of intercellular adhesion molecule 1 and production of TNF-alpha in human peripheral blood mononuclear cells2008
- Author(s)
  Hamano R, Takahashi HK, Iwagaki H, Kanke T, Liu K, Yoshino T, Sendo T, Nishibori M, Tanaka N
- Journal Title
  
  Shock 29(2)
  
  Pages: 154-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590534
[Journal Article] The immunosuppressive effects of nicotine during human mixed lymphocyte reaction2007
- Author(s)
  Takahashi HK, Iwagaki H, Hamano R, Kanke T, Liu K, Sadamori H, Yagi T, Yoshino T, Tanaka N, Nishibori M
- Journal Title
  
  Eur J Pharmacol 559(1)
  
  Pages: 69-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590534
[Journal Article] Anti-high mobility group box 1 monoclonal antibody ameliorates brain infarction induced by transient ischemia in rats2007
- Author(s)
  Liu K, Mori S, Takahashi HK, Tomono Y, Wake H, Kanke T, Sato Y, Hiraga N, Adachi N, Yoshino T, Nishibori M.
- Journal Title
  
  FASEB J 21(14)
  
  Pages: 3904-16
- NAID
  130004903140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590534
[Journal Article] Action profiles of statins and calcineurin inhibitors during human mixed lymphocyte reaction2007
- Author(s)
  Takahashi HK, Iwagaki H, Yagi T, Kanke T, Liu K, Yoshino T, Tanaka N, Nishibori M
- Journal Title
  
  Clin Immunol 123(3)
  
  Pages: 324-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590534
[Journal Article] Effect of amodiaquine, a histamine N-methyltransferase inhibitor, on, Propionibacterium acnes and lipopolysaccharide-induced hepatitis in mice2007
- Author(s)
  Yokoyama A, Mori S, Takahashi HK, Kanke T, Wake H, Nishibori M
- Journal Title
  
  Eur J Pharmacol 558(1-3)
  
  Pages: 179-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590534
[Journal Article] The regulation of ICAM-1 and LFA-1 interaction by autacoids and statins : a novel strategy for controlling inflammation and immune responses.2003
- Author(s)
  Nishibori M
- Journal Title
  
  Journal of Pharmacological Sciences 92(1)
  
  Pages: 7-12
- NAID
  130000073674
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590228
[Journal Article] The regulation of ICAM-1 and LFA-1 interaction by autacoids and statins : a novel strategy for controlling inflammation and immune responses.2003
- Author(s)
  Nishibori M
- Journal Title
  
  Journal of Pharmacological Sciences 92(1)
  
  Pages: 7-12
- NAID
  130000073674
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590467
[Journal Article] MAP kinase-mediated proliferation of DLD-1 carcinoma by the stimulation of protease-activated receptor 22003
- Author(s)
  Atsushi Jikuhara, Hiromi Iwagaki, Masahiro Nishibori
- Journal Title
  
  Life Sciences 73
  
  Pages: 2817-2829
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591408
[Journal Article] The regulation of ICAM-1 and LFA-1 interaction by autacoids and statins : a novel strategy for controlling inflammation and immune responses.2003
- Author(s)
  Nishibori M
- Journal Title
  
  Journal of Pharmacological Sciences 92
  
  Pages: 7-12
- NAID
  130000073674
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590228
[Journal Article] The regulation of ICAM-1 and LFA-1 interaction by autacoids and statins : a novel strategy for controlling inflammation and immune responses.2003
- Author(s)
  Nishibori M
- Journal Title
  
  Journal of Pharmacological Science 92(1)
  
  Pages: 7-12
- NAID
  130000073674
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590467
[Journal Article] MAP kinase-mediated proliferation of DLD-1 carcinoma by the stimulation Of protease-activated receptor 22003
- Author(s)
  Atsushi Jikuhara, Hiromi Iwagaki, Masahiro Nishibori, et al.
- Journal Title
  
  Life Sciences 73
  
  Pages: 2817-2929
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591408
[Journal Article] Peroxiredoxin family proteins are key initiators of post-ischemic inflammation in the brain
- Author(s)
  Shichida T., Nishibori M., et al.(18名、14番目)
- Journal Title
  
  Nature Medicine
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390071
[Journal Article] Anti-High Mobility Group Box-1 Antibody Therapy for Traumatic Brain Injury
- Author(s)
  Okuma Y., Liu K., Wake H., Nishibori M., et al.(16名、16番目)
- Journal Title
  
  Annals of Neurology
  
  Volume: (in press)
- NAID
  130004427993
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390071
[Patent] ANTIBODY-DRUG CONJUGATES AND USE OF ANTIBODIES FOR DRUG DELIVERY2021
- Inventor(s)
  西堀正洋、森秀治、高尚澤、阪口政清、友野靖子
- Industrial Property Rights Holder
  岡山大学、医療法人創和会
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-19H03408
[Patent] USE OF ANTIBODY-DRUG CONJUGATES AND ANTIBODIES FOR DRUG DELIVERY2021
- Inventor(s)
  西堀正洋、森秀治、高尚澤、阪口政清、友野靖子
- Industrial Property Rights Holder
  岡山大学、医療法人創和会
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-19H03408
[Patent] USE OF ANTIBODY-DRUG CONJUGATES AND ANTIBODIES FOR DRUG DELIVERY2021
- Inventor(s)
  西堀正洋、森秀治、高尚澤、阪口政清、友野靖子
- Industrial Property Rights Holder
  岡山大学、医療法人創和会
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-19H03408
[Patent] 抗体薬物コンジュゲート及び抗体の薬物送達のための使用2021
- Inventor(s)
  西堀正洋、森秀治、高尚澤、阪口政清、友野靖子
- Industrial Property Rights Holder
  岡山大学、医療法人創和会
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Acquisition Date
  2021
- Data Source
  KAKENHI-PROJECT-19H03408
[Patent] 抗体薬物コンジュゲート及び抗体の薬物送達のための使用2020
- Inventor(s)
  西堀正洋、森秀治、高尚澤、阪口政清、友野靖子
- Industrial Property Rights Holder
  岡山大学、医療法人創和会
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Overseas
- Data Source
  KAKENHI-PROJECT-19H03408
[Patent] 抗体薬物コンジュゲート及び抗体の薬物送達のための使用2019
- Inventor(s)
  西堀正洋、森秀治、高尚澤、阪口政清、友野靖子
- Industrial Property Rights Holder
  岡山大学、医療法人創和会
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-228542
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-19H03408
[Patent] 赤血球保護剤2018
- Inventor(s)
  西堀正洋、和氣秀徳、衷輝、森秀治、阪口政清
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-15H04686
[Patent] 赤血球保護剤2017
- Inventor(s)
  西堀正洋、和氣秀徳、衷輝、森秀治、阪口政清
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-028738
- Filing Date
  2017-02-20
- Data Source
  KAKENHI-PROJECT-15H04686
[Patent] 好中球活性化に起因する疾患の治療薬、治療方法および検査方法2016
- Inventor(s)
  西堀正洋、髙橋英夫、他
- Industrial Property Rights Holder
  西堀正洋、髙橋英夫、他
- Industrial Property Rights Type
  特許
- Filing Date
  2016-01-14
- Acquisition Date
  2016-11-29
- Overseas
- Data Source
  KAKENHI-PROJECT-15K08253
[Patent] THERAPEUTIC AGENT, METHOD OF TREATMENT AND METHOD FOR PREDICTING THE SEVERITY OF SYSTEMIC INFLAMMATORY RESPONSE SYNDROME(SIRS), DISEASES CAUSED OR ACCOMPANIED BY NEUTROPHIL ACTIVATION2016
- Inventor(s)
  西堀正洋、森秀治、和氣秀徳、髙橋英夫、劉克約、勅使川原匡　他3名
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Rights Type
  特許
- Filing Date
  2016
- Acquisition Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-15H04686
[Patent] 好中球活性化に起因する疾患の治療薬、治療方法及び検査方法2016
- Inventor(s)
  西堀　正洋、黒田　浩佐、森松　博史、森　秀治ほか５名
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Rights Type
  特許
- Filing Date
  2016-01-14
- Overseas
- Data Source
  KAKENHI-PROJECT-15H04686
[Patent] 遺伝子発現用カセット及びその産生物2015
- Inventor(s)
  阪口　政清、西堀　正洋ほか４名
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-198160
- Filing Date
  2015-10-06
- Data Source
  KAKENHI-PROJECT-15H04686
[Patent] 好中球活性化に起因する疾患の治療薬及び検査方法2015
- Inventor(s)
  西堀正洋、森秀治、和氣秀徳、髙橋英夫、劉克約　ほか2名
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Rights Type
  特許
- Filing Date
  2015
- Acquisition Date
  2017
- Data Source
  KAKENHI-PROJECT-15H04686
[Patent] サイトカインストーム抑制剤2015
- Inventor(s)
  西堀　正洋、森　秀治、和氣　秀徳
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Rights Type
  特許
- Filing Date
  2015-12-21
- Overseas
- Data Source
  KAKENHI-PROJECT-15H04686
[Patent] サイトカインストーム抑制剤2015
- Inventor(s)
  西堀　正洋、森　秀治、和氣　秀徳
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-154972
- Filing Date
  2015-08-05
- Data Source
  KAKENHI-PROJECT-15H04686
[Patent] サイトカインストーム抑制剤2014
- Inventor(s)
  西堀正洋、森秀治、和氣秀徳
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-258546
- Filing Date
  2014-12-22
- Data Source
  KAKENHI-PROJECT-25670464
[Patent] インフルエンザ治療剤2014
- Inventor(s)
  西堀正洋、劉克約、塚原宏一、森島恒雄、八代将登、野坂宜之
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Rights Type
  特許
- Filing Date
  2014-12-26
- Data Source
  KAKENHI-PROJECT-24590658
[Patent] インフルエンザ治療剤2014
- Inventor(s)
  西堀正洋、劉克約、塚原宏一、森島恒雄、八代将登、野坂宜之
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-265514
- Filing Date
  2014-12-26
- Data Source
  KAKENHI-PROJECT-24390061
[Patent] 好中球活性化に起因する疾患の治療薬、治療方法及び検査方法2013
- Inventor(s)
  西堀正洋、森秀治、和氣秀徳、髙橋英夫、劉克約、勅使川原匡
- Industrial Property Rights Holder
  西堀正洋、森秀治、和氣秀徳、髙橋英夫、劉克約、勅使川原匡
- Industrial Property Rights Type
  特許
- Filing Date
  2013-05-28
- Overseas
- Data Source
  KAKENHI-PROJECT-25670464
[Patent] 好中球活性化に起因する疾患の治療薬、治療方法及び検査方法2013
- Inventor(s)
  西堀正洋
- Industrial Property Rights Holder
  西堀正洋
- Industrial Property Rights Type
  特許
- Filing Date
  2013-05-28
- Data Source
  KAKENHI-PROJECT-24590337
[Patent] B細胞悪性リンパ腫治療薬2013
- Inventor(s)
  西堀正洋外6名
- Industrial Property Rights Holder
  岡山大学、医療法人創和会
- Acquisition Date
  2013-03-22
- Overseas
- Data Source
  KAKENHI-PROJECT-23659687
[Patent] ヒト化抗HMGB1抗体もしくはその抗原結合性断片2013
- Inventor(s)
  高田賢蔵、寅嶋崇、西堀正洋
- Industrial Property Rights Holder
  高田賢蔵、寅嶋崇、西堀正洋
- Industrial Property Rights Type
  特許
- Filing Date
  2013-12-06
- Overseas
- Data Source
  KAKENHI-PROJECT-24390061
[Patent] 好中球活性化調節剤2012
- Inventor(s)
  西堀正洋他
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Rights Type
  特許
- Filing Date
  2012-06-06
- Data Source
  KAKENHI-PROJECT-23659687
[Patent] 好中球活性化調節剤2012
- Inventor(s)
  西堀正洋他
- Industrial Property Rights Holder
  西堀正洋他
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-129232
- Filing Date
  2012-06-06
- Data Source
  KAKENHI-PROJECT-24590658
[Patent] 好中球活性化調節剤2012
- Inventor(s)
  西堀正洋, 他
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Number
  2012-129232
- Filing Date
  2012-06-06
- Data Source
  KAKENHI-PROJECT-24390061
[Patent] THERAPEUTIC AGENT, TREATMENT METHOD AND TEST METHOD FOR DISEASES ASSOCIATED WITH ACTIVATION OF NEUTROPHILS2012
- Inventor(s)
  西堀正洋森秀治和氣秀徳高橋英夫劉克約勅使川匡原等
- Industrial Property Rights Holder
  西堀正洋森秀治和氣秀徳高橋英夫劉克約勅使川匡原等
- Industrial Property Rights Type
  特許
- Filing Date
  2012-06-06
- Acquisition Date
  2013-12-12
- Overseas
- Data Source
  KAKENHI-PROJECT-24590658
[Patent] 好中球活性化調節剤2012
- Inventor(s)
  西堀正洋外 5 名
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Number
  2012-129232
- Filing Date
  2012-06-06
- Overseas
- Data Source
  KAKENHI-PROJECT-23659687
[Patent] 好中球活性化調節剤2012
- Inventor(s)
  西堀正洋,森秀治,和氣秀徳,髙橋英夫,劉克約,勅使河原匡
- Industrial Property Rights Holder
  西堀正洋,森秀治,和氣秀徳,髙橋英夫,劉克約,勅使河原匡
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-129232
- Filing Date
  2012-06-06
- Data Source
  KAKENHI-PROJECT-24590337
[Patent] RAGEとAGEの結合抑制剤のスクリーニング方法2010
- Inventor(s)
  西堀正洋、森秀治、高橋英夫、和氣秀徳、劉克約
- Industrial Property Rights Holder
  国立大学法人岡山大学
- Industrial Property Number
  2010-214019
- Filing Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21659141
[Patent] RAGEとAGEの結合抑制剤のスクリーニング方法2010
- Inventor(s)
  西堀正洋、森秀治、高橋英夫、和氣秀徳、劉克約
- Industrial Property Rights Holder
  西堀正洋、森秀治、高橋英夫、和氣秀徳、劉克約
- Industrial Property Number
  2010-214019
- Filing Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-20590539
[Patent] RAGEとAGEの結合抑制剤のスクリーニング方法2010
- Inventor(s)
  西堀正洋、森秀治、高橋英夫、和氣秀徳、劉克約
- Industrial Property Rights Holder
  西堀正洋、森秀治、高橋英夫、和氣秀徳、劉克約
- Industrial Property Number
  2010-214019
- Filing Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21590594
[Patent] RAGEとAGEの結合抑制剤のスクリーニング方法2010
- Inventor(s)
  西堀正洋、森秀治、高橋英夫、和氣秀徳、劉克約
- Industrial Property Rights Holder
  国立大学法人岡山大学
- Industrial Property Number
  2010-214019
- Filing Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21390071
[Patent] 外傷性神経障害治療剤2010
- Inventor(s)
  西堀正洋、森秀治、高橋英夫、和氣秀徳、劉克約、伊達勲、大熊佑、友野靖子
- Industrial Property Rights Holder
  西堀正洋、森秀治、高橋英夫、和氣秀徳、劉克約、伊達勲、大熊佑、友野靖子
- Industrial Property Number
  2010-270133
- Filing Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-21590594
[Patent] RAGEとAGEの結合抑制剤のスクリーニング方法2010
- Inventor(s)
  西堀正洋他4名
- Industrial Property Rights Holder
  西堀正洋他4名
- Industrial Property Number
  2010-214019
- Filing Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21390071
[Patent] 外傷性神経障害治療剤2010
- Inventor(s)
  西堀正洋、森秀治、高橋英夫、和氣秀徳、劉克約、伊達勲、大熊佑、友野靖子
- Industrial Property Rights Holder
  国立大学法人岡山大学、医療法人創和会
- Industrial Property Number
  2010-270133
- Filing Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-21659141
[Patent] 外傷性神経障害治療剤2010
- Inventor(s)
  西堀正洋他7名
- Industrial Property Rights Holder
  西堀正洋他7名
- Industrial Property Number
  2010-270133
- Filing Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-21390071
[Patent] 外傷性神経障害治療剤2010
- Inventor(s)
  西堀正洋、森秀治、高橋英夫、和氣秀徳、劉克約、伊達勲、大熊佑、友野靖子
- Industrial Property Rights Holder
  国立大学法人岡山大学、医療法人創和会
- Industrial Property Number
  2010-270133
- Filing Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-21390071
[Patent] 外傷性神経障害治療剤2010
- Inventor(s)
  西堀正洋、森秀治、高橋英夫、和氣秀徳、劉克約、伊達勲、大熊佑、友野靖子
- Industrial Property Rights Holder
  西堀正洋、森秀治、高橋英夫、和氣秀徳、劉克約、伊達勲、大熊佑、友野靖子
- Industrial Property Number
  2010-214019
- Filing Date
  2010-12-23
- Data Source
  KAKENHI-PROJECT-20590539
[Patent] アデローム動脈硬化抑制剤2009
- Inventor(s)
  西堀正洋、森秀治、高橋英夫、友野靖子、足立尚登、劉克約
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Number
  2009-223472
- Filing Date
  2009-09-28
- Data Source
  KAKENHI-PROJECT-21590594
[Patent] アテローム動脈硬化抑制剤2009
- Inventor(s)
  西堀正洋他5名
- Industrial Property Rights Holder
  西堀正洋他5名
- Industrial Property Number
  2009-223472
- Filing Date
  2009-09-28
- Data Source
  KAKENHI-PROJECT-21390071
[Patent] アテローム動脈硬化抑制剤2009
- Inventor(s)
  西堀正洋,高橋英夫,森秀治,劉克約,友野靖子,ベイカーメディカルリサーチインスティチュート
- Industrial Property Rights Holder
  西堀正洋,高橋英夫,森秀治,劉克約,友野靖子,ベイカーメディカルリサーチインスティチュート
- Industrial Property Number
  2009-223472
- Filing Date
  2009-09-28
- Data Source
  KAKENHI-PROJECT-20590539
[Patent] CEREBRAL VASOSPASM INHIBITOR2009
- Inventor(s)
  西堀正洋, 他
- Industrial Property Rights Holder
  岡山大学
- Filing Date
  2009-02-04
- Overseas
- Data Source
  KAKENHI-PROJECT-19659061
[Patent] CEREBRAL INFARCTION-PREVENTIVE AGENT2008
- Inventor(s)
  西堀正洋, 他
- Industrial Property Rights Holder
  岡山大学愛媛大学
- Filing Date
  2008-07-23
- Overseas
- Data Source
  KAKENHI-PROJECT-19659061
[Patent] 脳血管攣縮抑制剤2006
- Inventor(s)
  西堀正洋
- Industrial Property Rights Holder
  西堀正洋
- Filing Date
  2006-05-19
- Data Source
  KAKENHI-PROJECT-17659159
[Patent] 脳梗塞抑制剤2005
- Inventor(s)
  西堀正洋
- Industrial Property Rights Holder
  西堀正洋
- Industrial Property Number
  2005-308949
- Filing Date
  2005-10-24
- Data Source
  KAKENHI-PROJECT-17659159
[Presentation] S100A8/A9 とその新制御分子のバランスで成立するがん転移の機序解明2023
- Author(s)
  友信奈保子, 木下理恵, 合原勇馬, Ni Luh Gede Yoni Komalasari, Fan Jiang, 村田等, 山本健一, 山内明, 近藤英作, 豊岡伸一, 西堀正洋, 阪口政清
- Organizer
  日本組織培養学会第95回大会
- Data Source
  KAKENHI-PROJECT-23K27439
[Presentation] 抗HMGB1抗体による脳内出血の治療：霊長類マーモセットを用いた検討2022
- Author(s)
  王登莉、逢坂大樹、喬寒棟、王紫儀、趙坤、勅使川原匡、西堀正洋
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] HMGB1 accelerates acute phase periodontitis by regulating macrophage polarization.2022
- Author(s)
  Hirai A, Ideguchi H, Yamashiro K, Aoyagi H, Yamamoto T, Nishibori M, Takashiba S.
- Organizer
  2022 International Association of Dental Research (IADR)2
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] 神経障害性疼痛マウスにおける認知機能傷害に対するHMGB1中和抗体の効果に関する検討2022
- Author(s)
  吉本夏輝、中島一恵、大畑一努、中村庸輝、王登莉、劉克約、和氣秀徳、吾郷由希夫、西堀正洋、森岡徳光
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] 敗血症における全身炎症とHMGB1の役割2022
- Author(s)
  西堀正洋
- Organizer
  第49回日本集中治療医学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] 抗リウマチ薬sulfasalazineはToll-like receptor 4 刺激によるマクロファージからのHMGB1遊離を抑制することで炎症性疼痛を軽減する2022
- Author(s)
  堂本莉紗、田村ひなの、関口富美子、坪田真帆、西堀正洋、川畑篤史
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] 血管内皮細胞におけるAGEスカベンジと血管新生2021
- Author(s)
  西中崇、ハティポール　オメル　ファルク、和氣秀徳、森秀治、西堀正洋、高橋英夫
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K06905
[Presentation] 血管内皮細胞におけるHMGB1の動態と修飾抗HMGB1mAbを用いたDDSがん治療2021
- Author(s)
  西堀正洋, 高尚澤, 友信奈保子, 阪口政清
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] Anti-high mobility group box-1 (HMGB1) antibody therapy for spinal cord ischemia-reperfusion injury in rabbits.2021
- Author(s)
  Muraoka G, Ousaka D, Wang D, Qiao H, Liu K, Nishibori M.
- Organizer
  ESVS 35th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] Roles of histidine-rich glycoprotein in prevention of hypertensive disorders of pregnancy and in physiological placental development.2021
- Author(s)
  Kiyoshi Teshigawara, Keyue Liu, Dengli Wang, Hidenori Wake, Shuji Mori, Hideo Kohka Takahashi, Masahiro Nishibori
- Organizer
  The 22nd World Congress of International Society for the Study of Hypertension in Pregnancy (ISSHP2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] 脊髄虚血再灌流障害に対する抗HMGB-1抗体の有効性の検討2021
- Author(s)
  村岡玄哉、劉克約、喬寒棟、逢坂大樹、王登莉、藤井泰宏、笠原真悟、西堀正洋
- Organizer
  第94回日本薬理学会
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] 卵巣摘出マウスにおけるパクリタキセル誘発性末梢神経障害およびHMGB1誘起アロディニアの増悪2021
- Author(s)
  貫戸綾乃、平本志於里、坪田真帆、松永浩明、宮本朋佳、小泉祐一、西堀正洋、川畑篤史
- Organizer
  第94回日本薬理学会
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] パーキンソン病における痛覚過敏へのhigh mobility group box-1中和抗体の抑制効果2021
- Author(s)
  佐藤史爽、中村庸輝、麻思萌、河内貴弘、中島一恵、王登莉、劉克約、和氣秀徳、西堀正洋、森岡徳光
- Organizer
  第94回日本薬理学会
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] マウス周産期における血漿高ヒスチジン糖タンパクの生理的動態解析2021
- Author(s)
  勅使川原匡、劉克約、王登莉、和氣秀徳、森秀治、髙橋英夫、西堀正洋
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] トロンビン阻害薬はHMGB1が関与する結腸痛と膀胱痛を増悪させる：内蔵痛制御における内因性トロンボモジュリン／トロンビン系の役割2021
- Author(s)
  山縣歩夢、松井和樹、坪田真帆、西堀正洋、川畑篤史
- Organizer
  第94回日本薬理学会
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] Anti-high mobility group box-1 (HMGB1) antibody therapy for spinal cord ischemia-reperfusion injury in rabbits2021
- Author(s)
  Genya Muraoka, Keyue Liu, Handong Qiao, Daiki Ousaka, Dengli Wang, Yasuhiro Fujii, Shingo Kasahara, Masahiro Nishibori
- Organizer
  第35回　European Society for Vascular Surgery 総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08823
[Presentation] 抗HMGB1抗体による硬膜下血腫の治療2020
- Author(s)
  王登莉、高尚澤、劉克約、和氣秀徳、勅使川原匡、森秀治、西堀正洋
- Organizer
  第43回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] 脳卒中易発症性高血圧ラットにおいてリンパ球数と血小板容積の変動は脳卒中症状の発現よりも先行する2020
- Author(s)
  西中崇、丹羽淳子、和氣秀徳、森秀治、西堀正洋、髙橋英夫
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K06905
[Presentation] Delayed Wound Healing after Tooth Extraction under Malnutrition2020
- Author(s)
  Y. ZHANG, H. IDEGUCHI, H. AOYAGI, K. YAMASHIRO, T. YAMAMOTO, M. NISHIBORI, S. TAKASHIBA
- Organizer
  Japanese Association for Dental Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10128
[Presentation] 好中球様細胞におけるHistidine-Rich Glycoprotein(HRG)の効果2020
- Author(s)
  吉井将哲、和氣秀徳、勅使川原匡、王登莉、劉克約、髙橋陽平、西堀正洋
- Organizer
  日本薬理学会（横浜、新型コロナのため誌上開催、2020年3月16日-18日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] LPS エンドトキシン血症マウスに対する抗酸化ストレス抗体の保護効果2020
- Author(s)
  喬寒棟、高尚澤、和気秀徳、劉克約、勅使川原匡、森秀治、西堀正洋
- Organizer
  日本薬理学会（横浜、新型コロナのため誌上開催、2020年3月16日-18日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] 終末糖化産物結合因子の探索研究とAGEs-RAGE結合遮断領域の同定2020
- Author(s)
  森秀治、渡邊政博、和氣秀徳、劉克約、勅使川原匡、高橋英夫、西堀正洋、豊村隆男
- Organizer
  日本薬理学会（横浜、新型コロナのため誌上開催、2020年3月16日-18日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] 抗HMGB1抗体による神経疾患とがん創薬2020
- Author(s)
  西堀正洋
- Organizer
  第41回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] HMGB1 中和抗体の局所投与はマウス遠位眼窩下神経慢性絞扼により発生する顔面感覚異常の発症を予防する2020
- Author(s)
  河内貴弘、中村庸輝、中島恵、劉克約、和氣秀徳、西堀正洋、入舩正浩、森岡徳光
- Organizer
  第137回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] 高ヒスチジン糖タンパク質は敗血症病態下における好中球の状態を制御する2020
- Author(s)
  和氣秀徳、森秀治、高橋英夫、王登莉、勅使川原匡、西堀正洋
- Organizer
  日本薬理学会（横浜、新型コロナのため誌上開催、2020年3月16日-18日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] ラットの脳内出血および硬膜下出血に対する抗HMGB1抗体の治療効果2020
- Author(s)
  王登莉、劉克約、和氣秀徳、勅使川原匡、森秀治、西堀正洋
- Organizer
  日本薬理学会（横浜、新型コロナのため誌上開催、2020年3月16日-18日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] HMGB1 Translocation in Neurons after Ischemic Insult: Subcellular Localization in Mitochondria and Peroxisomes.2020
- Author(s)
  王登莉、劉克約、勅使川原匡、和氣秀徳、西堀正洋
- Organizer
  第137回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] 胎盤形成と妊娠期高血圧における血漿高ヒスチジン糖タンパクの生理的役割の解析2020
- Author(s)
  勅使川原匡、劉克約、和氣秀徳、王登莉、森秀治、髙橋英夫、西堀正洋
- Organizer
  日本薬理学会（横浜、新型コロナのため誌上開催、2020年3月16日-18日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] HRGの作用により球状化した好中球の機能評価2020
- Author(s)
  高橋陽平、和氣秀徳、勅使川原匡、Wang Dengli、吉井将哲、西堀正洋
- Organizer
  日本薬理学会（横浜、新型コロナのため誌上開催、2020年3月16日-18日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] Histamine induced high mobility group box 1 release from vascular endothelial cells.2020
- Author(s)
  Gao S, Wake H, Liu K, Wang D, Teshigawara K, Nishibori M.
- Organizer
  第22回日本ヒスタミン学会
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] ラットの脳内出血および硬膜下出血に対する抗HMGB1抗体の治療効果2020
- Author(s)
  王登莉、劉克約、和氣秀徳、勅使川原匡、森秀治、西堀正洋
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] エストロゲン欠乏によるパクリタキセル誘発性末梢神経障害の増悪：HMGB1の関与について2020
- Author(s)
  貫戸綾乃、平本志於里、坪田真帆、宮本朋佳、小泉祐一、西堀正洋、川畑篤史
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] 眼窩下神経慢性絞扼モデルマウスに対する神経傷害部位へのHMGB1中和抗体投与は三叉神経領域における疼痛様行動を抑制する2020
- Author(s)
  河内貴弘、中村庸輝、中島一恵、劉克約、和氣秀徳、西堀正洋、入舩正浩、森岡徳光
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] Histidine-rich glycoprotein inhibits high mobility group box 1-mediated pathway in vascular endothelial cells.2019
- Author(s)
  Shangze Gao, Hidenori Wake, Sakaguchi Masakiyo, Dengli Wang, Shuji Mori, Keyue Liu, Kiyoshi Teshigawara, Yuan Gao, Hideo Takahashi, Masahiro Nishibori.
- Organizer
  9th International DAMPs and Alarmins Symposium (Okayama, JAPAN, Nov 06-08/2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] マウスにおいて肝障害により放出されるHMGB1はボルテゾミブ誘発性末梢神経障害を増悪させる2019
- Author(s)
  堂本莉紗、宮本朋佳、関口富美子、坪田真帆、小泉祐一、西堀正洋、川畑篤史
- Organizer
  第135回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] インターアルファインヒビタータンパクは好中球形態を制御し、活性酸素分子種産生を抑制することによって好中球の静穏状態を維持する2019
- Author(s)
  HTWE SOE SOE、和氣秀徳、劉克約、勅使川原匡、Stonestreet Barbara S.、Lim Yow-Pin、西堀正洋
- Organizer
  日本薬理学会（大阪、2019年3月14日-16日）
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] Histidine-rich glycoprotein inhibits high mobility group box 1-mediated pathway in vascular endothelial cells.2019
- Author(s)
  Gao S, Wake H, Sakaguchi M, Wang D, Mori S, Liu K, Teshigawara K, Gao Y, Takahashi H, Nishibori M.
- Organizer
  9th International DAMPs and Alarmins Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] The role of HMGB1 in oral inflammation and regeneration.2019
- Author(s)
  Yamashiro K, Ideguchi H, Aoyagi H, Yoshihara-Hirata C, Kawamura M, Yamasaki M, Kyoshima-Suzuki R, Yao Z, Hirai A, Wake H, Nishibori M, Yamamoto T, Takashiba A.
- Organizer
  9th International DAMPs and Alarmins Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] 血管内皮細胞のHMGB1信号経路におけるHistidine-rich glycoproteinの阻止作用2019
- Author(s)
  高尚澤、和気秀徳、高遠、王登莉、劉克約、勅使川原匡、西堀正洋
- Organizer
  日本薬理学会（大阪、2019年3月14日-16日）
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] Association with brain tissue/intracranial vessels and HMGB1 in rats fed a high-fat diet.2019
- Author(s)
  Takahashi Y, Liu K, Yamaoka Y, Nishi K, Mura S, Kidani N, Hiramatsu M, Hishikawa T, Sugiu K, Nishibori M, Date I.
- Organizer
  9th International DAMPs and Alarmins Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] AGEs結合因子の分子同定と炎症性サイトカイン発現応答への影響2019
- Author(s)
  森秀治、渡邊政博、和氣秀徳、勅使川原匡、劉克約、高橋英夫、西堀正洋、豊村隆男
- Organizer
  日本分子生物学会年会（福岡、2019年12月3-6日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] Roles and mechanisms of neuroinflammation in stress and depression.2019
- Author(s)
  Furuyashiki T, Ukeshima S, Kitaoka S, Nie X, Liu K, Wake H, Teshigawara K, Nishibori M.
- Organizer
  American College of Neuropsychopharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] Roles of innate immune signaling for repeated stress-induced behavioral changes.2019
- Author(s)
  Nie X, Kitaoka S, Ayaka T, Ukeshima S, Nishibori M, Furuyashiki T.
- Organizer
  Neuro-immune axis: reciprocal regulation in development, health, and disease.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] 終末糖化産物による炎症応答と細胞増殖応答2019
- Author(s)
  豊村隆男、渡邊政博、和氣秀徳、勅使川原匡、劉克約、高橋英夫、西堀正洋、森秀治
- Organizer
  日本分子生物学会年会（福岡、2019年12月3-6日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] マウスにおけるbortezomib誘発性末梢神経障害の発症および維持におけるHMGB1の役割とその起源2019
- Author(s)
  池田裕哉、宮崎貴也、坪田真帆、冨田詩織、関口富美子、西堀正洋、川畑篤史
- Organizer
  第135回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] AGEs と炎症関連分子の共存が炎症反応に与える変化の検討2019
- Author(s)
  渡邊政博、豊村隆男、和氣秀徳、劉克約、勅使川原匡、高橋英夫、西堀正洋、森秀治
- Organizer
  日本薬理学会近畿部会（大阪、2019年11月23日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] 周産期における高ヒスチジン糖タンパク（HRG）の生理的役割の解析2019
- Author(s)
  勅使川原匡、劉克約、和氣秀徳、王登莉、髙橋英夫、森秀治、西堀正洋
- Organizer
  日本薬理学会近畿部会（岐阜、2019年6月21日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] Roles of innate immune molecules in repeated stress-induced neuronal and behavioral changes.2019
- Author(s)
  Shiho Kitaoka, Ayaka Tomohiro, Shinya Ukeshima, Keyue Liu, Hidenori Wake, Kiyoshi Teshigawara, Masahiro Nishibori, Tomoyuki Furuyashiki.
- Organizer
  9th International DAMPs and Alarmins Symposium (Okayama, JAPAN, Nov 06-08/2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] Roles of innate immune molecules in repeated stress-induced neuronal and behavioral changes.2019
- Author(s)
  Kitaoka S, Tomohiro A, Ukeshima S, Liu K, Wake H, Teshigawara K, Nishibori M, Furuyashiki T.
- Organizer
  9th International DAMPs and Alarmins Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] 高ヒスチジン糖タンパク遺伝子欠損マウスにおける妊娠高血圧の病態解析2019
- Author(s)
  勅使川原匡、劉克約、和氣秀徳、王登莉、髙橋英夫、森秀治、西堀正洋
- Organizer
  日本薬理学会（大阪、2019年3月14日-16日）
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] Anti-HMGB1 mAb therapy for intracerebral and subdural hemorrhage in rats.2019
- Author(s)
  Wang D, Liu K, Wake H, Teshigawara K, Mori S, Nishibori M.
- Organizer
  9th International DAMPs and Alarmins Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] HRGの作用により球状化したヒト好中球の貪食機能解析2019
- Author(s)
  高橋陽平、和氣秀徳、吉井將哲、阪口政清、劉克約、勅使川原匡、高橋英夫、森秀治、西堀正洋
- Organizer
  日本薬理学会近畿部会（岐阜、2019年6月21日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] 炎症誘発活性を有する新規AGEs結合分子の同定2019
- Author(s)
  渡邊政博、豊村隆男、和氣秀徳、劉克約、勅使川原匡、高橋英夫、西堀正洋、森秀治
- Organizer
  日本薬理学会近畿部会（岐阜、2019年6月21日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] 好中球様細胞におけるHistidine-Rich Glycoprotein(HRG)の影響2019
- Author(s)
  吉井将哲、和氣秀徳、高橋陽平、王登莉、勅使川原匡、西堀正洋
- Organizer
  日本薬理学会近畿部会（岐阜、2019年6月21日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] 脳障害の鍵分子としてのHMGB1:脳卒中、脳外傷からてんかんまで2019
- Author(s)
  西堀正洋
- Organizer
  第49回日本神経精神薬理学会
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] Prior treatment with anti-HMGB1 antibody boosts human neural stem cell transplantation-mediated functional recovery after spinal cord injury.2019
- Author(s)
  Uezono N, Nakashima K, Nishibori M, Taniguchi N.
- Organizer
  9th International DAMPs and Alarmins Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] Perineural treatment with anti-HMGB1 antibody alleviates trigeminal neuropathy in mouse with chronic constriction injury of distal infraorbital nerve.2019
- Author(s)
  Kochi T, Nakamura Y, Hisaoka-Nakashima K, Liu K, Wake H, Nishibori M, Irifune M, Morioka N.
- Organizer
  9th International DAMPs and Alarmins Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] Anti-HMGB1 mAb therapy for intracerebral and subdural hemorrhage in rats.2019
- Author(s)
  Dengli Wang, Keyue Liu, Hidenori Wake, Kiyoshi Teshigawara, Shuji Mori, Masahiro Nishibori.
- Organizer
  9th International DAMPs and Alarmins Symposium (Okayama, JAPAN, Nov 06-08/2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] High mobility group box-1 は三叉神経障害に起因する痛覚異常の発症に寄与する2019
- Author(s)
  中村庸輝、河内貴弘、中島一恵、劉克約、和氣秀徳、西堀正洋、入船正浩、森岡徳光
- Organizer
  生体機能と創薬シンポジウム2019
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] 終末糖化産物はラクトフェリンに結合し，ラクトフェリン誘導性TNF-α発現応答を抑制する2019
- Author(s)
  森秀治、渡邊政博、和氣秀徳、劉克約、勅使川原匡、高橋英夫、西堀正洋、豊村隆男
- Organizer
  日本薬理学会 (大阪、2019年3月14日-16日)
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] エストロゲンはパクリタキセル誘発性末梢神経障害に対して抑制的に作用する：マクロファージ由来HMGB1との関係について2019
- Author(s)
  貫戸綾乃、平本志於里、宮本朋佳、坪田真帆、小泉祐一、西堀正洋、川畑篤史
- Organizer
  生体機能と創薬シンポジウム2019
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] マウス反復社会挫折ストレスによる社会忌避行動の誘導におけるHMGB1の役割2019
- Author(s)
  北岡志保、友廣彩夏、請島慎也、劉克約、和氣秀徳、勅使川原匡、西堀正洋、古屋敷智之
- Organizer
  第135回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] てんかん病態におけるHMGB1動態と末梢投与抗HMGB1抗体の治療効果2019
- Author(s)
  西堀正洋
- Organizer
  NEURO2019
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] Circulating Inter-alpha Inhibitor proteins and DAMPs: interaction to‘DAMPening’ systemic and neuro-inflammation.2019
- Author(s)
  Yow-Pin Lim, Ray Chen, Barbara Stonestreet, Joseph Qiu, Andre Santoso, Kiyoshi Teshigawara, Masahiro Nishibori.
- Organizer
  9th International DAMPs and Alarmins Symposium (Okayama, JAPAN, Nov 06-08/2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] マウス反復社会挫折ストレスによる社会忌避行動の誘導におけるHMGB1の役割2019
- Author(s)
  北岡志保、友廣彩夏、請島慎也、劉克約、和氣秀徳、勅使川原匡、西堀正洋、古屋敷智之
- Organizer
  日本薬理学会近畿部会（岐阜、2019年6月21日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] 高ヒスチジン糖タンパク遺伝子欠損マウスにおける妊娠高血圧、及び、胎盤形成異常の解析2019
- Author(s)
  勅使川原匡、劉克約、和氣秀徳、王登莉、髙橋英夫、森秀治、西堀正洋
- Organizer
  日本内分泌学会（仙台、2019年5月9日-11日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] Advanced glycation end products の細胞内取り込みによる血管新生の調節機構2019
- Author(s)
  西中崇、山﨑由衣、丹羽淳子、和氣秀徳、森秀治、西堀正洋、髙橋英夫
- Organizer
  第136回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-18K06905
[Presentation] Advanced glycation end products による血管新生促進機序に対するエンドサイトーシスの関与2019
- Author(s)
  山﨑由衣、西中崇、丹羽淳子、森秀治、和氣秀徳、劉克約、西堀正洋、髙橋英夫
- Organizer
  第135回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-18K06905
[Presentation] 卵巣摘出マウスにおけるパクリタキセル誘発性末梢神経障害の増悪：HMGB1の関与について2019
- Author(s)
  平本志於里、貫戸綾乃、宮本朋佳、坪田真帆、小泉祐一、西堀正洋、川畑篤史
- Organizer
  第136回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] Enhanced M2 polarization of macrophage and angiogenesis by interleukin-182019
- Author(s)
  Takashi Nishinaka, Yui Yamazaki, Atsuko Niwa, Hidenori Wake, Shuji Mori,Tadashi Yoshino, Masahiro Nishibori Hideo Takahashi
- Organizer
  第9回国際DAMPs とAlarmins シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06905
[Presentation] Therapeutic time window of anti-high mobility group box-1 antibody administration in mouse model of spinal cord injury.2019
- Author(s)
  Nakajo M, Uezono N, Nakashima H, Wake H, Nishibori M, Nakashima K, Tanagushi N.
- Organizer
  9th International DAMPs and Alarmins Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] Advanced glycation end products interact with lactoferrin, and change the lactoferrin-stimulated proinflammatory cytokine response.2019
- Author(s)
  Shuji Mori, Masahiro Watanabe, Hidenori Wake, Kiyoshi Teshigawara, Keyue Liu, Hideo Takahashi, Masahiro Nishibori, Takao Toyomura.
- Organizer
  9th International DAMPs and Alarmins Symposium (Okayama, JAPAN, Nov 06-08/2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] 高ヒスチジン糖タンパク（histidine-rich glycoprotein）遺伝子欠損マウスの妊娠期表現型の解析2018
- Author(s)
  勅使川原匡、劉克約、和氣秀徳、王登莉、髙橋英夫、森秀治、西堀正洋
- Organizer
  日本薬理学会近畿部会（広島、2018年6月1日）
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] Anti-High Mobility Group Box-1 Antibody Therapy Might Prevent Cognitive Dysfunction After Traumatic Brain Injury.2018
- Author(s)
  Yu Okuma, Keyue Liu, Hidenori Wake, Kiyoshi Teshigawara, Shuji Mori, Hideo K Takahashi, Nobuyuki Hirotsune, Shigeki Nishino, Masahiro Nishibori.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018). (Japan, Kyoto,Jul 1-6/2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] The role of histidine-rich glycoprotein on immunothrombosis in septic organ failure.2018
- Author(s)
  Wake H, Mori S, Teshigawara K, Liu K, Wang D, Gao Y, Takahashi HK, Nishibori M.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] Effects of Histidine-Rich Glycoprotein on Erythrocyte Aggregation and Hemolysis: Implications for a Role under Septic Conditions.2018
- Author(s)
  Hui Zhong, Hidenori Wake, Keyue Liu, Yuan Gao, Kiyoshi Teshigawara, Masakiyo Sakaguchi, Shuji Mori, Masahiro Nishibori.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018). (Japan, Kyoto,Jul 1-6/2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] Visualization of advanced glycation end-products phagocytosis by macrophages and identification of possible receptor2018
- Author(s)
  Hamasaki S, Kobori T, Kitaura A, Yamazaki Y, Nishinaka T, Niwa A, Nakao S, Nishibori M, Takahashi H
- Organizer
  18th WORLD CONGRESS OF BASIC AND CLINICAL PHARMACOLOGY
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06905
[Presentation] Protective Effects of Histidine-rich Glycoprotein on Barrier Dysfunction of Vascular Endothelial Cells.2018
- Author(s)
  Shangze Gao, Yuan Gao, Hidenori Wake, Keyue Liu, Kiyoshi Teshigawara, Shiji Mori, Masahiro Nishibori.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018). (Japan, Kyoto,Jul 1-6/2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] The effects of histidine-rich glycoprotein on neutrophil-like differentiated cell lines.2018
- Author(s)
  Yukinori Yoshii, Hidenori Wake, Kiyoshi Teshigawara, Keyue Liu, Dengli Wang, Yohei Takahashi, Masahiro Nishibori.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018). (Japan, Kyoto,Jul 1-6/2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] ダメージ関連分子HMGB1の糖代謝制御への関与の検討2018
- Author(s)
  兼森玄、勅使川原匡、劉克約、和氣秀徳、王登莉、高橋英夫、森秀治、西堀正洋
- Organizer
  西日本医学生学術フォーラム2018（三重、2018年12月15日）
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] 脳卒中後疼痛に対する脊髄HMGB1およびその関連受容体の関与2018
- Author(s)
  松浦歩、原田慎一、劉克約、西堀正洋、徳山尚吾
- Organizer
  第133回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] 炎症惹起因子HMGB1の糖代謝制御に対する生理的役割の検討2018
- Author(s)
  兼森玄、勅使川原匡、劉克約、和氣秀徳、王登莉、高橋英夫、森秀治、西堀正洋
- Organizer
  日本薬理学会近畿部会（神戸、2018年11月23日）
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] HMGB1 translocation induced by histamine in vascular endothelial cells in vitro2018
- Author(s)
  Nishibori M, Gao S, Gao Y, Wake H, Liu K, Teshigawara K, Mori S.
- Organizer
  World Histamine Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] Characterization of histidine-rich glycoprotein (HRG) production under the experimental pathological conditions.2018
- Author(s)
  Kiyoshi Teshigawara, Atsuko Niwa, Hidenori Wake, Dengli Wang, Keyue Liu, Shuji Mori, Hideo Takahashi, Masahiro Nishibori.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018). (Japan, Kyoto,Jul 1-6/2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] Protective effect of histidine rich glycoprotein (HRG) on human vascular endothelial cells.2018
- Author(s)
  Gao Y, Wake H, Liu K, Teshigawara K, NishiboriM.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] 遺伝子改変細胞を用いたDAMPs分子の作用メカニズム解析2018
- Author(s)
  渡邊政博、豊村隆男、和氣秀徳、劉克約、勅使川原匡、高橋英夫、西堀正洋、森秀治
- Organizer
  日本薬理学会近畿部会（広島、2018年6月1日）
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] The role of histidine-rich glycoprotein on immunothrombosis in septic organ failure.2018
- Author(s)
  Hidenori Wake, Shuji Mori, Kiyoshi Teshigawara, Keyue Liu, Dengli Wang, Yuan Gao, Hideo K Takahashi, Masahiro Nishibori.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018). (Japan, Kyoto,Jul 1-6/2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] Specific action mediated by spinal HMGB1 receptors in the induction of central post-stroke pain.2018
- Author(s)
  Matsuura W, Harada S, Liu K, Nishibori M, Tokuyama S.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] Protective effects of Histidine-rich glycoprotein on human vascular endothelial cells.2018
- Author(s)
  Yuan Gao, Hidenori Wake, Keyue Liu, Kiyoshi Teshigawara, Shuji Mori, Masahiro Nishibori.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018). (Japan, Kyoto,Jul 1-6/2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] マクロファージによる終末糖化産物の取り込みに対する硫酸化多糖類の影響2018
- Author(s)
  西中崇、山﨑由衣、丹羽淳子、森秀治、和氣秀徳、西堀正洋、髙橋英夫
- Organizer
  第134回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-18K06905
[Presentation] Therapeutic effects of anti-HMGB1 monoclonal antibody on pilocarpine-induced status epilepticus in mice.2018
- Author(s)
  Nishibori M, Fu L, Wake H, Wang D, Teshigawara K, Liu K, Takahashi HK, Mori S.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] AGEs-TWEAK相互作用による炎症応答の制御2018
- Author(s)
  森秀治、渡邊政博、和氣秀徳、劉克約、勅使川原匡、高橋英夫、西堀正洋、豊村隆男
- Organizer
  日本生化学会（京都、2018年9月24-26日）
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] Anti-HMGB1 mAb therapy for intracerebral hemorrhage-induced brain injury in rats.2018
- Author(s)
  Wang D, Liu K, Wake H, Teshigawara K, Mori S, Nishibori M.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] 抗HMGB1抗体による脳内出血の治療2018
- Author(s)
  王登莉、劉克約、和氣秀徳、勅使川原匡、森秀治、西堀正洋
- Organizer
  第41回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] Effects of inter-alpha inhibitor proteins (IAIP) on neutrophil functions.2018
- Author(s)
  Htwe SS, Wake H, Liu K, Teshigawa K, Stonestreet BS, Lim YP, Nishibori M.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] Therapeutic effects of anti-HMGB1 monoclonal antibody on pilocarpine-induced status epilepticus in mice.2018
- Author(s)
  Masahiro Nishibori, Li Fu, Hidenori Wake, Dengli Wang, Kiyoshi Teshigawara, Keyue Liu, Hideo K Takahashi, Shuji Mori.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018). (Japan, Kyoto,Jul 1-6/2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] Protective Effects of Histidine-rich Glycoprotein on Barrier Dysfunction of Vascular Endothelial Cells.2018
- Author(s)
  Gao S, Gao Y, Wake H, Liu K, Teshigawara K, Mori S, Nishibori M
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] Characterization of histidine-rich glycoprotein (HGR) production under the experimental pathological conditions2018
- Author(s)
  Teshigawara K, Niwa A, Wake H, Liu K, Mori S, Takahashi H, Nishibori M
- Organizer
  18th WORLD CONGRESS OF BASIC AND CLINICAL PHARMACOLOGY
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06905
[Presentation] 炎症惹起因子HMGB1の糖代謝制御に対する生理的役割の検討2018
- Author(s)
  兼森玄、勅使川原匡、劉克約、和氣秀徳、王登莉、髙橋英夫、森秀治、西堀正洋
- Organizer
  第134回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] Screening of sulfated polysaccharide and sugar-related compounds as the regulator of advanced glycation end-products by macrophage2018
- Author(s)
  Nishinaka T, Kobori T, , Hamasaki S, Kitaura A, Niwa A, Mori S, Nishibori M, Takahashi H
- Organizer
  18th WORLD CONGRESS OF BASIC AND CLINICAL PHARMACOLOGY
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06905
[Presentation] Intereleukin-18 amplifies M2 polarization of macrophage which leads excessive angiogenesis2018
- Author(s)
  Yamazaki Y, Kobori T, Niwa A, Nishinaka T, Mori S, Nishibori M, Takahashi H
- Organizer
  18th WORLD CONGRESS OF BASIC AND CLINICAL PHARMACOLOGY
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06905
[Presentation] Advanced glycation end products による血管新生促進機序の解明2018
- Author(s)
  山﨑由衣、西中崇、丹羽淳子、森秀治、和氣秀徳、西堀正洋、髙橋英夫
- Organizer
  第134回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-18K06905
[Presentation] Anti-high mobility group box-1 antibody therapy might prevent cognitive dysfunction after traumatic brain injury.2018
- Author(s)
  Okuma Y, Liu K, Wake H, Teshigawara K, Mori S, Takahashi HK, Hirotsune N, Nishino S, Nishibori M.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] Pathophysiological role of a factor affecting AGEs-RAGE interaction on endothelial cell responses.2018
- Author(s)
  Shuji Mori, Masahiro Watanabe, Hidenori Wake, Keyue Liu, Kiyoshi Teshigawara, Hideo Takahashi, Masahiro Nishibori.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018). (Japan, Kyoto,Jul 1-6/2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] Anti-HMGB1 mAb therapy for intracerebral hemorrhage-induced brain injury in rats.2018
- Author(s)
  Dengli Wang, Keyue Liu, Hidenori Wake, Kiyoshi Teshigawara, Shuji Mori, Masahiro Nishibori.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018). (Japan, Kyoto,Jul 1-6/2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] 高ヒスチジン糖タンパク遺伝子欠損マウスにおける妊娠高血圧症候群様表現型の解析2018
- Author(s)
  勅使川原匡、劉克約、兼森玄、和氣秀徳、王登莉、髙橋英夫、森秀治、西堀正洋
- Organizer
  日本薬理学会近畿部会（神戸、2018年11月23日）
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] マクロファージと血管内皮細胞の細胞間相互作用による血管新生促進機構の解析2018
- Author(s)
  小堀宅郎、濱﨑真一、北浦淳寛、山﨑由衣、西中崇、丹羽淳子、西堀正洋、髙橋英夫
- Organizer
  第138回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-15K08253
[Presentation] 新規敗血症治療薬及び診断マーカーHistidine-rich glycoproteinの開発2018
- Author(s)
  和氣秀徳、森秀治、王登莉、勅使川原匡、西堀正洋
- Organizer
  日本生化学会（京都、2018年9月24-26日）
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] マクロファージと血管内皮細胞の細胞間相互作用による血管新生促進機構の解析2018
- Author(s)
  小堀宅郎、濱崎真一、北浦淳寛、山﨑由衣、西中崇、丹羽淳子、西堀正洋、髙橋英夫
- Organizer
  第138回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] 高ヒスチジン糖タンパク（histidine-rich glycoprotein, HRG）と結合親和性をもつ炎症関連血漿タンパクの探索解析2018
- Author(s)
  勅使川原匡、丹羽淳子、衷輝、和氣秀徳、劉克約、王登莉、高橋英夫、森秀治、西堀正洋
- Organizer
  日本生化学会（京都、2018年9月24-26日）
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] 脊椎HMGB1関連受容体/グリア細胞/NOSシグナルを介する脳卒中後疼痛の発現機序の解明2018
- Author(s)
  松浦渉、原田慎一、劉克約、西堀正洋、徳山尚吾
- Organizer
  第138回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] The analysis of anxiety-and depression-related behaviors in neuropathic pain of mice possible involvement of brain inflammation.2018
- Author(s)
  Hisaoka-Nakashima K, Tomimura Y, Yoshii T, Zhang FF, Nakamura Y, Liu K, Nishibori M, Nakata Y, Morioka N.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] 敗血症病態におけるNETsと免疫血栓形成に対する高ヒスチジン糖タンパク質の役割2017
- Author(s)
  和氣秀徳、森秀治、高橋英夫、劉克約、勅使川原匡、西堀正洋
- Organizer
  日本薬理学会
- Place of Presentation
  長崎
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] 炎症性メディエーターHMGB1が歯槽骨治癒における血管新生の遺伝子発現を促進する2017
- Author(s)
  青柳浩明，山城圭介，吉原千暁，井手口英隆，山本直史，河村麻理，下江正幸，本郷昌一，劉克約，西堀正洋，高柴正悟
- Organizer
  第38回炎症再生医学会
- Data Source
  KAKENHI-PROJECT-16K20670
[Presentation] Histidine-rich glycoprotein protects vascular endothelial cells and red blood cells in sepsis.2017
- Author(s)
  Wake H, Gao Y, Hui Z, Gao S, Mori S, Morimatsu H, Nishibori M.
- Organizer
  Sepsis2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] 脊椎HMGB1関連受容体/グリア細胞/NOSシグナルを介する脳卒中後疼痛の発現機序の解明2017
- Author(s)
  松浦渉、原田慎一、劉克約、西堀正洋、徳山尚吾
- Organizer
  第138回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] Novel understanding of cellular and molecular basis of sepsis pathophysiology: a proposal of new treatment strategy.2017
- Author(s)
  Nishibori M.
- Organizer
  International Seminar and workshop on Advanced Cellular and molecular Biology Techniques
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] Histidine-rich glycoprotein (HRG) の血管内皮細胞保護の効果2017
- Author(s)
  高尚澤、和氣秀徳、劉克約、勅使川原匡、西堀正洋
- Organizer
  日本薬理学会
- Place of Presentation
  長崎
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] ヒト血管内皮細胞におけるHistidine rich-glycoprotein (HRG) の保護効果2017
- Author(s)
  高遠、和氣秀徳、劉克約、勅使川原匡、森秀治、西堀正洋
- Organizer
  日本薬理学会
- Place of Presentation
  長崎
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] 抗HMGB1抗体による脳内出血の治療2017
- Author(s)
  王登莉、劉克約、和氣秀徳、勅使川原匡、森秀治、西堀正洋
- Organizer
  日本薬理学会
- Place of Presentation
  長崎
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] メトホルミンはHMGB1 に直接結合しその炎症促進作用を抑制する2017
- Author(s)
  坂田菜摘、堀内崇弘、鳴海善洋、木村朋寛、林隆史、長野圭介、劉克約、西堀正洋、突田壮平、山田哲也、片桐秀樹、白川龍太郎、堀内久徳
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] Protective effects of histidine-rich glycoprotein on barrier function of vascular endothelial cells.2017
- Author(s)
  Gao S, Gao Y, Wake H, Liu K, Teshigawara K, Mori S, Nishibori M.
- Organizer
  第131回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] EFFECTS OF INTER-ALPHA INHIBITOR PROTEINS (IAIP) ON THE SHAPE AND REACTIVE OXYGEN SPECIES (ROS) PRODUCTION IN PURIFIED HUMAN NEUTROPHILS2017
- Author(s)
  Soe Soe Htwe、Hidenori Wake、Keyue Liu、Kiyoshi Teshigawara、Yow Pin Lim、Masahiro Nishibori
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎県長崎市）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] EFFECTS OF INTER-ALPHA INHIBITOR PROTEINS (IAIP) ON THE SHAPE AND REACTIVE OXYGEN SPECIES (ROS) PRODUCTION IN PURIFIED HUMAN NEUTROPHILS2017
- Author(s)
  Soe Soe Htwe, Hidenori Wake, Keyue Liu, Kiyoshi Teshigawara, Yow Pin Lim, Masahiro Nishibori
- Organizer
  日本薬理学会
- Place of Presentation
  長崎
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] 敗血症病態の新しい理解と血漿タンパク質Histidine-rich glycoprotein(HRG)を用いた治療法開発2017
- Author(s)
  西堀　正洋
- Organizer
  第35回サイトプロテクション研究会
- Place of Presentation
  メルパルク京都（京都府京都市）
- Year and Date
  2017-03-10
- Invited
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] Protective effects of histidine-rich glycoprotein (HRG) on vascular endothelial cells2017
- Author(s)
  高尚澤、和氣秀徳、劉克約、勅使川原匡、西堀正洋
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎県長崎市）
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] 神経障害性疼痛モデルマウスにおけるうつ様行動とHMGB1発現解析2017
- Author(s)
  富村昌暉、中島一恵、吉井稔紀、張　芳芳、劉　克約、西堀正洋、仲田義啓、森岡徳光
- Organizer
  第132回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] Anti-HMGB1 therapy for intracerebral hemorrhage2017
- Author(s)
  王登莉、劉克約、和氣秀徳、勅使川原匡、森秀治、西堀正洋
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] Histidine rich-glycoprotein regulates erythrocyte PS expression adherent and aggregation2017
- Author(s)
  衷輝、和氣秀徳、劉克約、勅使川原匡、西堀正洋
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎県長崎市）
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] 脳卒中後疼痛に対する脊髄HMGB1関連受容体シグナルおよびグリア細胞の関与2017
- Author(s)
  松浦歩、原田慎一、劉克約、西堀正洋、徳山尚吾
- Organizer
  第132回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] Protective effects of histidine-rich glycoprotein (HRG) on human vascular endothelial cells2017
- Author(s)
  高遠、和氣秀徳、劉克約、勅使川原匡、森秀治、西堀正洋
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎県長崎市）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] Histidine-rich glycoprotein (HRG)の好中球制御による敗血症治療薬の可能性2017
- Author(s)
  和氣秀徳、高遠、森秀治、劉克約、勅使川原匡、西堀正洋
- Organizer
  第132回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] The role of histidine-rich glycoprotein on NETosis and immunothrombosis in septic condition2017
- Author(s)
  和氣秀徳、森秀治、高橋英夫、劉克約、勅使川原匡、西堀正洋
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎県長崎市）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] 赤血球のPSエクスプレション、吸着と疑集におけるHistidine rich-glycoprotein の調節機構2017
- Author(s)
  衷輝、和氣秀徳、劉克約、勅使川原匡、西堀正洋
- Organizer
  日本薬理学会
- Place of Presentation
  長崎
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] 抗HMGB1モノクローナル抗体によるピロカルピン誘導性癲癇マウスの病態改善効果の検討2017
- Author(s)
  富麗、劉克約、和氣秀徳、勅使川原匡、高橋英夫、森秀治、西堀正洋
- Organizer
  日本薬理学会
- Place of Presentation
  長崎
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] 脳卒中後疼痛における脊髄のhigh mobility group box-1/nitiric oxide synthetaseシグナルの関与2017
- Author(s)
  松浦渉、原田慎一、劉克約、西堀正洋、徳山尚吾
- Organizer
  第131回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] 脊髄後角におけるHMGB1 による疼痛惹起メカニズムに対するIL-1βの関与2017
- Author(s)
  宮内一希、張芳芳、中島一恵、劉克約、西堀正洋、仲田義啓、森岡徳光
- Organizer
  第132回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] Hitidine-Rich Glycoprotein as a Novel Prognostic Blomarker for Sepsis: Multicenter prospective observational study.2017
- Author(s)
  Kuroda K, Morimatsu H, Kawanoue N, Wake H, Mori S, Nishibori M.
- Organizer
  Sepsis2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] IL-18 はオステオポンチンを介してマクロファージ M2 分化と血管新生作用を増強する2017
- Author(s)
  小堀宅郎、濱崎真一、北浦淳寛、西中　崇、丹羽淳子、森秀治、西堀正洋、髙橋英夫
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール、長崎新聞文化ホール
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-15K08253
[Presentation] 抗HMGB1抗体はマウスのピロカルピン誘発痙攣におけるBBB破綻と脳内炎症からマウスを保護する2017
- Author(s)
  西堀正洋、富麗、劉克約、和氣秀徳、高橋英夫、森秀治
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] Role of spinal high mobility group box-1 associated receptors in the induction of central post-stroke pain and the involvement of glia cells in this mechanism2017
- Author(s)
  松浦渉、原田慎一、劉克約、西堀正洋、徳山尚吾
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] ヒト血管内皮細胞におけるHistidine rich glycoprotein（HRG）の保護効果2016
- Author(s)
  高遠、和氣秀徳、劉克約、勅使川原匡、森秀治、西堀正洋
- Organizer
  日本薬理学会
- Place of Presentation
  横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] AGEs親和性因子としての60S ribosomal proteinの単離2016
- Author(s)
  森秀治、渡邊政博、和氣秀徳、劉克約、勅使川原匡、高橋英夫、西堀正洋、豊村隆男
- Organizer
  日本生化学会
- Place of Presentation
  仙台
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] 抗HMGB1抗体による脳内出血の治療2016
- Author(s)
  王登莉、劉克約、和氣秀徳、勅使川原匡、森秀治、西堀正洋
- Organizer
  日本薬理学会
- Place of Presentation
  横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] Anti-HMGB1 neutralizing antibody attenuates cytokine secretion and progression of periodontitis2016
- Author(s)
  C. YOSHIHARA，K. YAMASHIRO，T. YAMAMOTO，H. IDEGUCHI，H. AOYAGI，M. SHIMOE，S. HONGO，M. KAWAMURA，K. Liu，M. NISHIBORI，S. TAKASHIBA，
- Organizer
  IADR/APR General Session & Exhibition
- Place of Presentation
  COEX Convention Center, Korea, Seoul
- Year and Date
  2016-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20670
[Presentation] Protective effects of histidine rich glycoprotein (HRG) on human vascular endothelial cells2016
- Author(s)
  高遠、和氣秀徳、劉克約、勅使川原匡、森秀治、西堀正洋
- Organizer
  第129回日本薬理学会近畿部会
- Place of Presentation
  広島県医師会館（広島県広島市）
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] ピロカルピン誘導性てんかんモデルマウスにおける抗HMGB1抗体の炎症抑制効果2016
- Author(s)
  富麗、劉克約、和氣秀徳、勅使川原匡、森秀治、西堀正洋
- Organizer
  日本薬理学会
- Place of Presentation
  横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] AGEsによるTNF関連分子の機能変化2016
- Author(s)
  渡邊政博、豊村隆男、和氣秀徳、劉克約、勅使川原匡、高橋英夫、西堀正洋、森秀治
- Organizer
  日本薬理学会近畿部会
- Place of Presentation
  京都
- Year and Date
  2016-11-19
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] Anti-HMGB1 mAb attenuates cerebral vasospasm and brain injury after subarachnoid hemorrhage in rats.2016
- Author(s)
  勅使川原匡、春間純、菱川朋人、王登莉、劉克約、和氣秀徳、森秀治、髙橋英夫、杉生憲志、伊達勲、西堀正洋
- Organizer
  日本薬理学会近畿部会
- Place of Presentation
  京都
- Year and Date
  2016-11-19
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] Anti-HMGB1 mAb attenuates cerebral vasospasm and brain injury after subarachnoid hemorrhage in rats2016
- Author(s)
  勅使川原匡、春間純、菱川朋人、王登莉、劉克約、和氣秀徳、森秀治、高橋英夫、杉生憲志、伊達勲、西堀正洋
- Organizer
  第130会日本薬理学会近畿部会
- Place of Presentation
  京都大学百周年時計台記念館
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] 70kD AGEs結合因子によるAGEsシグナリングへの影響2016
- Author(s)
  森秀治、渡邊政博、和氣秀徳、劉克約、勅使川原匡、高橋英夫、西堀正洋、豊村隆男
- Organizer
  日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] ストレプトゾトシン誘発糖尿病ラットにおけるAdvanced glycation end-productsの検出2016
- Author(s)
  森岡祐太、和氣秀徳、勅使川原匡、劉克約、森秀治、西堀正洋
- Organizer
  日本薬理学会
- Place of Presentation
  横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] 敗血症時好中球微小循環イメージング2016
- Author(s)
  和氣　秀徳、森　秀治、高橋　英夫、劉　克約、勅使川原　匡、西堀　正洋
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] 敗血症性ARDSにおけるimmunothrombus形成に対する高ヒスチジン糖タンパク質の役割2016
- Author(s)
  和氣秀徳、森秀治、高橋英夫、劉克約、勅使川原匡、西堀正洋
- Organizer
  日本生化学会
- Place of Presentation
  仙台
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] Damps関連サイトカインの機能に対するAGEsの影響2016
- Author(s)
  渡邊政博、豊村隆男、和氣秀徳、劉克約、勅使川原匡、高橋英夫、西堀正洋、森秀治
- Organizer
  日本生化学会
- Place of Presentation
  仙台
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] 敗血症性ARDSにおけるImmunothrombosis2016
- Author(s)
  和氣　秀徳、西堀　正洋
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] 破骨細胞分化過程に対して非炎症分子SHILsが及ぼす影響2016
- Author(s)
  豊村隆男、渡邉政博、和氣秀徳、勅使川原匡、劉克約、高橋英夫、西堀正洋、森秀治
- Organizer
  日本生化学会
- Place of Presentation
  仙台
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] 敗血症時好中球微小循環イメージング2016
- Author(s)
  和氣秀徳、森秀治、高橋英夫、劉克約、勅使川原匡、西堀正洋
- Organizer
  日本薬理学会
- Place of Presentation
  横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] ヒト血管内皮細胞におけるHistidine rich glycoprotein (HRG) の保護効果2016
- Author(s)
  高　遠、和氣　秀徳、劉　克約、勅使川原　匡、森　秀治、西堀　正洋
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] Endotoxemia併発急性膵炎に対するHistidine-rich gloycoprotein(HRG)の動態及び治療効果2016
- Author(s)
  寺尾欣也、和氣秀徳、森岡祐太、勅使川原匡、劉克約、高橋英夫、森秀治、西堀正洋
- Organizer
  第129回日本薬理学会近畿部会
- Place of Presentation
  広島県医師会館（広島県広島市）
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] Histidine rich glycoproteinの敗血症時好中球性微小循環障害に対する影響2016
- Author(s)
  和氣秀徳、森秀治、劉克約、勅使川原匡、西堀正洋
- Organizer
  第129回日本薬理学会近畿部会
- Place of Presentation
  広島県医師会館（広島県広島市）
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] 敗血症性ARDSにおけるimmunothrombus形成に対する高ヒスチジン糖タンパク質の役割2016
- Author(s)
  和氣秀徳、森秀治、高橋英夫、劉克約、勅使川原匡、西堀正洋
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] ラット脳内出血モデルにおける2次性炎症反応と抗HMGB1抗体効果2016
- Author(s)
  西堀正洋、王登莉、劉克約、和氣秀徳、勅使川原匡、森秀治
- Organizer
  第37回日本炎症・再生医学会，京都，2016
- Place of Presentation
  京都市勧業館みやこめっせ
- Data Source
  KAKENHI-PROJECT-16K08909
[Presentation] 非炎症分子SHILsはサイトカインとともに破骨細胞分化を調節する2016
- Author(s)
  豊村隆男、渡邊政博、和氣秀徳、勅使川原匡、劉克約、高橋英夫、西堀正洋、森秀治
- Organizer
  日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K08232
[Presentation] Histidine-Rich Glycoprotein as a Novel Prognostic Biomarker in Critically Ill Patients.2015
- Author(s)
  Kuroda K, Morimatsu H, Wake H, Mori S, Nishibori M.
- Organizer
  Euroanaesthesia 2015 (Annual meeting of European Society of Anesthesiology)
- Place of Presentation
  Berlin（Germany）
- Year and Date
  2015-05-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] The effects of anti-HMGB1 antibody on pilocarpine-induced epilepsy in mice.2015
- Author(s)
  Fu L, Liu K, Wake H, Teshigawara K, Mori S, Nishibori M.
- Organizer
  7th International Symposium DAMPS and HMGB1.
- Place of Presentation
  Germany, Bonn, University Hospital Bonn.
- Year and Date
  2015-09-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] 敗血症病態における微小循環障害に対する高ヒスチジン糖タンパク質の役割2015
- Author(s)
  和氣　秀徳、森　秀治、高橋　英夫、劉　克約、勅使川原　匡、西堀　正洋
- Organizer
  第38回日本分子生物学会年会　第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] 敗血症病態の新しい理解と治療法開発2015
- Author(s)
  西堀　正洋
- Organizer
  第6回岡山敗血症治療学術講演会
- Place of Presentation
  メルパルク岡山（岡山県岡山市）
- Year and Date
  2015-07-10
- Invited
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] Tissue factor ( TF ) 誘発DICモデルにおけるHistidine-rich glycoprotein ( HRG ) の動態及び治療効果について2015
- Author(s)
  寺尾　欣也、和氣　秀徳、森岡　祐太、勅使川原　匡、劉　克約、高橋　英夫、森　秀治、西堀　正洋
- Organizer
  第127回日本薬理学会近畿部会
- Place of Presentation
  長良川国際会議場（岐阜県岐阜市）
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] 高ヒスチジン糖タンパク質（HRG）の敗血症性immunothrombosis形成に対する影響2015
- Author(s)
  和氣　秀徳、森　秀治、劉　克約、勅使川原　匡、西堀　正洋
- Organizer
  第128回日本薬理学会近畿部会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府豊中市）
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] 敗血症病態における高ヒスチジン糖タンパク質（HRG）の好中球形態と微小循環に対する影響2015
- Author(s)
  和氣秀徳、森秀治、劉克約、勅使川原匡、西堀正洋
- Organizer
  日本薬理学会近畿部会
- Place of Presentation
  岐阜
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] 敗血症病態における高ヒスチジン糖タンパク質（HRG）の好中球形態と微小循環に対する影響2015
- Author(s)
  和氣　秀徳、森　秀治、劉　克約、勅使川原　匡、西堀　正洋
- Organizer
  第127回日本薬理学会近畿部会
- Place of Presentation
  長良川国際会議場（岐阜県岐阜市）
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] Anti-HMGB1 therapy for intracerebral hemorrhage.2015
- Author(s)
  Wang D, Liu K, Wake H, Teshigawara K, Mori S, Nishibori M.
- Organizer
  7th International Symposium DAMPS and HMGB1.
- Place of Presentation
  Germany, Bonn, University Hospital Bonn.
- Year and Date
  2015-09-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] 第2回神戸外科浄化療法研究会2015
- Author(s)
  西堀　正洋
- Organizer
  敗血症と多臓器不全の新しい理解と治療法開発
- Place of Presentation
  生田神社会館（兵庫県神戸市）
- Year and Date
  2015-10-23
- Invited
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] Tissue factor(TF)誘発DICモデルにおけるHistidine-rich glycoprotein(HRG)の動態及び治療効果について2015
- Author(s)
  寺尾欣也､和氣秀徳､森岡祐太､勅使河原匡､劉克約､髙橋英夫､森秀治、西堀正洋
- Organizer
  第127回日本薬理学会近畿部会
- Place of Presentation
  長良川国際会議場（岐阜県）
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-15K08253
[Presentation] Tissue factor ( TF ) 誘発DICモデルにおけるHistidine-rich glycoprotein ( HRG ) の動態及び治療効果について2015
- Author(s)
  寺尾欣也、和氣秀徳、森岡祐太、勅使川原匡、劉克約、髙橋英夫、森秀治、西堀正洋
- Organizer
  日本薬理学会近畿部会
- Place of Presentation
  岐阜
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] SIRSにおける新たな重症度バイオマーカーとしてのHistidine-Rich Glycoprotein：前向き観察研究2015
- Author(s)
  黒田　浩佐、森松　博史、和氣　秀徳、森　秀治、西堀　正洋
- Organizer
  日本麻酔科学会第62回学術集会
- Place of Presentation
  神戸ポートピアホテル（兵庫県神戸市）
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] Receptor for advanced glycation end product と肺障害2014
- Author(s)
  出石恭久、和氣秀徳、劉克約、勅使川原匡、高橋英夫、森秀治、西堀正洋
- Organizer
  日本薬理学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] コラゲナーゼ誘発脳内出血モデルにおける抗HMGB1単クローン抗体の効果2014
- Author(s)
  劉克約、王登莉、和氣秀徳、勅使川原匡、髙橋英夫、森秀治、西堀正洋
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] Endotoxin血症併発急性膵炎に対するHistidine Rich Grycoprotein（HRG）の効果2014
- Author(s)
  寺尾欣也、和氣秀徳、森岡祐太、勅使川原匡、劉克約、森秀治、高橋英夫、西堀正洋
- Organizer
  日本薬理学会近畿部会
- Place of Presentation
  岡山
- Year and Date
  2014-06-20
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] コラゲナーゼで誘発脳内出血モデルにおける抗HMGB1単クローン抗体の効果2014
- Author(s)
  劉克約、王登莉、和氣秀徳、勅使川原匡、髙橋英夫、森秀治、西堀正洋
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター(仙台)
- Year and Date
  2014-03-20
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] 炎症誘発因子HMGB1とインスリン抵抗性の関係についての検討2014
- Author(s)
  衷輝、勅使川原匡、和氣秀徳、劉克約、西堀正洋
- Organizer
  日本薬理学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] 自発運動は脳卒中後の視床下部神経再生を促進する2014
- Author(s)
  丹羽淳子、赤星保光、堀内喜高、濱崎真一、小堀宅郎、西堀正洋、高橋英夫
- Organizer
  第125回日本薬理学会近畿部会
- Place of Presentation
  岡山コンベンションセンター（岡山市）
- Year and Date
  2014-06-20
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] Endotoxin血症併発急性膵炎に対するHistidine Rich Grycoprotein (HRG) の効果2014
- Author(s)
  寺尾欣也、和氣秀徳、森岡祐太、勅使川原匡、劉克約、森秀治、高橋英夫、西堀正洋
- Organizer
  第125回日本薬理学会近畿部会
- Place of Presentation
  岡山コンベンションセンター（岡山市）
- Year and Date
  2014-06-20
- Data Source
  KAKENHI-PROJECT-25670464
[Presentation] 脳神経傷害とhigh mobility group box-1(HMGB1)2014
- Author(s)
  西堀正洋
- Organizer
  第61回日本麻酔科学会学術集会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2014-05-17
- Invited
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] 循環好中球制御不全による敗血症性ARDSとHRG補充効果2014
- Author(s)
  和氣秀徳、森秀治、劉克約、勅使川原匡、西堀正洋
- Organizer
  第126回日本薬理学会近畿部会
- Place of Presentation
  和歌山県JAビル（和歌山市）
- Year and Date
  2014-10-24
- Data Source
  KAKENHI-PROJECT-25670464
[Presentation] AGEs結合親和性に基づいたAGEs遮断ペプチドの同定2014
- Author(s)
  横山隆太、豊村隆男、和氣秀徳、勅使川原匡、劉克約、高橋英夫、西堀正洋、森秀治
- Organizer
  第125回日本薬理学会近畿部会
- Place of Presentation
  岡山コンベンションセンター（岡山市）
- Year and Date
  2014-06-20
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] マウス腹膜擦過性肥厚のヒスタミンH1作用による抑制2014
- Author(s)
  足立尚登、劉克約、西堀正洋
- Organizer
  第18回日本ヒスタミン学会，神戸，2014
- Place of Presentation
  都ホテルニューアルカイック
- Year and Date
  2014-10-10
- Data Source
  KAKENHI-PROJECT-24590658
[Presentation] AGEs結合親和性に基づいたAGEs遮断ペプチドの同定2014
- Author(s)
  横山隆太、豊村隆男、和氣秀徳、勅使川原匡、劉克約、髙橋英夫、西堀正洋、森秀治
- Organizer
  第125回日本薬理学会近畿部会，岡山，2014
- Place of Presentation
  岡山コンベンションセンター
- Year and Date
  2014-06-20
- Data Source
  KAKENHI-PROJECT-24590658
[Presentation] Endotoxin血症併発急性膵炎に対するHistidine Rich Grycoprotein (HRG) の効果2014
- Author(s)
  寺尾欣也、和氣秀徳、森岡祐太、勅使川原匡、劉克約、森秀治、髙橋英夫、西堀正洋
- Organizer
  第125回日本薬理学会近畿部会，岡山，2014
- Place of Presentation
  岡山コンベンションセンター
- Year and Date
  2014-06-12
- Data Source
  KAKENHI-PROJECT-24590658
[Presentation] 循環好中球制御不全による敗血症性ARDSとHRG補充効果2014
- Author(s)
  和氣秀徳、森秀治、劉克約、勅使川原匡、西堀正洋
- Organizer
  第126回日本薬理学会近畿部会，和歌山，2014
- Place of Presentation
  和歌山県JAビル
- Year and Date
  2014-10-24
- Data Source
  KAKENHI-PROJECT-24590658
[Presentation] 自発運動は脳卒中後の視床下部神経再生を促進する2014
- Author(s)
  丹羽淳子、赤星保光、堀内喜高、濱﨑真一、小堀宅郎、西堀正洋、髙橋英夫
- Organizer
  第125回日本薬理学会近畿部会
- Place of Presentation
  岡山コンベンションセンター
- Year and Date
  2014-06-20
- Data Source
  KAKENHI-PROJECT-24590337
[Presentation] 可溶性トロンボモジュリンおよび抗HMGB1中和抗体はlipopolysaccharideあるいはsubstance P膀胱内注入により誘起される膀胱痛を抑制する2014
- Author(s)
  久保里紗、坪田真帆、関口富美子、石倉宏恭、西堀正洋、川畑篤史
- Organizer
  第125回日本薬理学会近畿部会
- Place of Presentation
  岡山コンベンションセンター（岡山市）
- Year and Date
  2014-06-20
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] Cyclophosphamide 誘起マウス膀胱炎モデルにおける膀胱痛発症メカニズムの解析：核内蛋白HMGB1と内因性H2Sの役割2014
- Author(s)
  山口薫、田中潤一、坪田真帆、関口富美子、関由加里、石倉宏恭、西堀正洋、川畑篤史
- Organizer
  第125回日本薬理学会近畿部会
- Place of Presentation
  岡山コンベンションセンター（岡山市）
- Year and Date
  2014-06-20
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] コラゲナーゼで誘発脳内出血モデルにおける抗HMGB1単クローン抗体の効果2014
- Author(s)
  劉克約、王登利、和氣秀徳、勅使川原匡、高橋英夫、森秀治、西堀正洋
- Organizer
  日本薬理学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] 高ヒスチジン糖タンパク（HRG）による敗血症治療の可能性2014
- Author(s)
  和氣秀徳、森秀治、高橋英夫、劉克約、勅使川原匡、西堀正洋
- Organizer
  日本薬理学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] HMGB1 によるヒスタミン誘導性免疫応答調節効果2014
- Author(s)
  濱﨑真一、丹羽淳子、小堀宅郎、西堀正洋、髙橋英夫
- Organizer
  第125回日本薬理学会近畿部会
- Place of Presentation
  岡山コンベンションセンター
- Year and Date
  2014-06-20
- Data Source
  KAKENHI-PROJECT-24590337
[Presentation] マクロファージ由来HMGB1の炎症性痛覚過敏への関与と分子作用メカニズムの解析2014
- Author(s)
  山岨大智、関由加里、山西広樹、坪田真帆、関口富美子、八木秀樹、益子高、西堀正洋、川畑篤史
- Organizer
  第126回日本薬理学会近畿部会
- Place of Presentation
  和歌山県JAビル（和歌山市）
- Year and Date
  2014-10-24
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] HMGB1によるヒスタミン誘導性免疫応答調節効果2014
- Author(s)
  濱崎真一、丹羽淳子、小堀宅郎、西堀正洋、高橋英夫
- Organizer
  第125回日本薬理学会近畿部会
- Place of Presentation
  岡山コンベンションセンター（岡山市）
- Year and Date
  2014-06-20
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] Protection of BBB disruption in ischemic and traumatic injuries by anti-HMGB1 monoclonal antibody2013
- Author(s)
  Nishibori M, Liu K, Okuma Y, Wake H, Teshigawara K, Takahashi H, Date I, Mori S
- Organizer
  Signalling in the Blood-Brain Barriers
- Place of Presentation
  Hotel Kapitany, Sumeg, Hungary
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] 抗HMGB1 抗体による脳外傷の治療2013
- Author(s)
  西堀正洋
- Organizer
  第3回HMGB1 シンポジウム
- Place of Presentation
  松本
- Year and Date
  2013-02-28
- Data Source
  KAKENHI-PROJECT-23659687
[Presentation] 高ヒスチジン糖タンパク質の好中球走化性に対する影響2013
- Author(s)
  和氣秀徳、森秀治、髙橋英夫、劉克約、勅使川原匡、西堀正洋
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場(福岡)
- Year and Date
  2013-03-21
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] 抗HMGB1抗体による脳外傷の治療2013
- Author(s)
  西堀正洋
- Organizer
  第3回HMGB1シンポジウム
- Place of Presentation
  松本(招待講演)
- Year and Date
  2013-02-28
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] Protection of BBB disruption in ischemic and traumatic injuries by anti-HMGB1 monoclonal antibody.2013
- Author(s)
  Nishibori M, Liu K, Okuma Y, Wake H, Teshigawara K, Takahashi H, Date I, Mori S.
- Organizer
  Signalling in the Blood-Brain Barriers.
- Place of Presentation
  Hotel Kapitany, Sumeg, Hungary.
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] Anti-HMGB1 Monoclonal Antibody Therapy for Traumatic Brain Injury in Rats2013
- Author(s)
  Nishibori M, Okuma Y, Liu K, Wake H, Maruo T, Teshigawara K, Yamamoto Y, Yamamoto H, Ohtsuka A, Yoshino T, Otani N, Tomura S, Shima K, Takahashi H, Date I, Mori S
- Organizer
  Merinoff World Congress 2013：HMGB1
- Place of Presentation
  Feinstein Institute for Medical Research, New York, USA
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] Protection of BBB disruption in ischemic and traumatic injuries by anti-HMGB1 monoclonal antibody2013
- Author(s)
  Nishibori M, Liu K, Okuma Y, Wake H, Teshigawara K, Takahashi H, Date I, Mori S
- Organizer
  Signalling in the Blood-Brain Barriers
- Place of Presentation
  Hotel Kapitány,Sümeg, Hungary
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] Anti-HMGB1 Monoclonal Antibody Therapy for Traumatic Brain Injury in Rats2013
- Author(s)
  Nishibori M, Okuma Y, Liu K, Wake H, Maruo T, Teshigawara K, Yamamoto Y, Yamamoto H, Ohtsuka A, Yoshino T, Otani N, Tomura S, Shima K, Takahashi H, Date I, Mori S
- Organizer
  Merinoff World Congress 2013 : HMGB1
- Place of Presentation
  Feinstein Institute for Medical Research, New York, USA
- Year and Date
  2013-10-09
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] ピルカルピンで誘発癲癇モデルにおける抗HMGB1単クローン抗体の効果2013
- Author(s)
  劉克約、富麗、和氣秀徳、勅使川原匡、西堀正洋
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場(福岡)
- Year and Date
  2013-03-22
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] Anti-HMGB1 Monoclonal Antibody Therapy for Traumatic Brain Injury in Rats2013
- Author(s)
  Nishibori Masahiro
- Organizer
  Merinoff World Congress 2013：HMGB1
- Place of Presentation
  Feinstein Institute for Medical Research, New York, U.S.A
- Data Source
  KAKENHI-PROJECT-24590658
[Presentation] Glycyrrhizin therapy for traumatic brain injury.2013
- Author(s)
  Okuma Y, Liu K, Wake H, Teshigawara K, Haruma J, Date I, Nishibori M.
- Organizer
  Shanghai BRAIN 2013.
- Place of Presentation
  Shanghai International Convention Center, Shanghai, China.
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] Protection of BBB disruption in ischemic and traumatic injuries by anti-HMGB1 monoclonal antibody2013
- Author(s)
  Nishibori Masahiro
- Organizer
  Signalling in the Blood-Brain Barriers
- Place of Presentation
  Hotel Kapitány,Sümeg, HUNGARY
- Data Source
  KAKENHI-PROJECT-24590658
[Presentation] 炎症性サイトカインHMGB1をターゲットにした新規脳梗塞治療抗体-抗体治療の展開2012
- Author(s)
  西堀正洋
- Organizer
  平成23年度バイオビジネスアワードJAPAN
- Place of Presentation
  大阪産業創造館4F
- Year and Date
  2012-02-17
- Data Source
  KAKENHI-PROJECT-21390071
[Presentation] 虚血時のBBB透過性亢進を濾出したEvans blue/Albuminの追跡検討2012
- Author(s)
  劉克約，張継勇,和氣秀徳，勅使川原匡，高橋英夫，森秀治，西堀正洋
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23659687
[Presentation] 抗HMGB1 抗体の臨床応用と創薬プラットフォーム構築2012
- Author(s)
  西堀正洋
- Organizer
  イノベーション研究会
- Place of Presentation
  大阪
- Year and Date
  2012-08-02
- Data Source
  KAKENHI-PROJECT-23659687
[Presentation] 抗HMGB1抗体の臨床応用と創薬プラットフォーム構築2012
- Author(s)
  西堀正洋
- Organizer
  イノベーション研究会
- Place of Presentation
  大阪(招待講演)
- Year and Date
  2012-08-02
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] 頭部外傷モデルを用いた抗HMDB1抗体の神経保護効果の検討2012
- Author(s)
  大熊佑、劉克約、和氣秀徳、勅使川原匡、高橋英夫、森秀治、伊達勲、西堀正洋
- Organizer
  第121回日本薬理学会近畿部会
- Place of Presentation
  あわぎんホール(徳島)
- Year and Date
  2012-06-29
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] 抗High Mobility Group Box-1抗体による脳梗塞、脳外傷、脳血管攣縮治療2012
- Author(s)
  西堀正洋
- Organizer
  生体機能と創薬シンポジウム2012
- Place of Presentation
  神戸(招待講演)
- Year and Date
  2012-08-30
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] マクロファージによるAdvanced glycation end product　(AGE)の細胞内取り込み2012
- Author(s)
  (13)周京秀，渋谷恵，和氣秀徳，劉克約，森岡祐太，岡村舞，森秀治，西堀正洋
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23659687
[Presentation] 抗High Mobility Group Box-1抗体による脳梗塞、脳外傷、脳血管攣縮治療2012
- Author(s)
  西堀正洋
- Organizer
  生体機能と創薬シンポジウム 2012
- Place of Presentation
  神戸
- Year and Date
  2012-08-30
- Data Source
  KAKENHI-PROJECT-23659687
[Presentation] 炎症性サイトカインHMGB1をターゲットにした新規脳梗塞治療抗体-抗体治療の展開.2012
- Author(s)
  西堀正洋
- Organizer
  平成23年度バイオビジネスアワードJAPAN
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23659687
[Presentation] ラットリンパ節細胞を用いた抗AGEモノクローナル抗体の作製2012
- Author(s)
  森岡祐太，友野靖子，和氣秀徳，劉克約，勅使川原匡，高橋英夫，森秀治，西堀正洋
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23659687
[Presentation] Anti-high mobility group box-1 antibody therapy for traumatic brain injury2012
- Author(s)
  Okuma Y, Liu K, Wake H, Maruo T, Teshigawara K, Tomura S, Otani N, Shima K, Yamamoto Y, Yamamoto H, Takahashi H, Mori S, Date I, Nishibori M
- Organizer
  Neuroscience 2012
- Place of Presentation
  New Orleans Morial Convention Center, New Orleans, USA
- Year and Date
  2012-10-16
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] 高ヒスチジン糖タンパク質はHMGB1-ヘパリン複合体誘導血管新生を抑制する2012
- Author(s)
  和氣秀徳，森秀治，高橋英夫，劉克約，勅使川原匡，西堀正洋
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23659687
[Presentation] 虚血時脳神経細胞内HMGB1は、核からペルオキシソーム/ミトコンドリアに移動する2012
- Author(s)
  福安悠介，劉克約，和氣秀徳，西村義人，勅使川原匡，西堀正洋
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23659687
[Presentation] HMGB1を標的とする脳血管疾患の抗体治療法開発2012
- Author(s)
  西堀正洋
- Organizer
  第22回脳血管シンポジウム
- Place of Presentation
  大阪(招待講演)
- Year and Date
  2012-09-08
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] 高ヒスチジン糖タンパク質はHMGB1-ヘパリン複合体誘導血管新生を抑制する2012
- Author(s)
  和氣秀徳、森秀治、髙橋英夫、劉克約、勅使川原匡、西堀正洋
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2012-03-15
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] HMGB1 を標的とする脳血管疾患の抗体治療法開発2012
- Author(s)
  西堀正洋
- Organizer
  第22回脳血管シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2012-09-08
- Data Source
  KAKENHI-PROJECT-23659687
[Presentation] 抗HMGB1単クローン抗体による虚血性脳障害の治療.第12回日本分子脳神経外科学会2011
- Author(s)
  西堀正洋
- Organizer
  日本脳神経外科学会第70回学術総会合同シンポジウム(招待講演)
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23659687
[Presentation] .HMGB1単クローン抗体によるラットMCAO誘発脳梗塞の治療2011
- Author(s)
  西堀正洋、劉克約、張継勇, 和氣秀徳, 大塚愛二，吉野正，伊達勲，高橋英夫, 森秀治
- Organizer
  第47回高血圧関連疾患モデル学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23659687
[Presentation] 高ヒスチジン糖タンパク質はHMGB1-ヘパリン複合体誘導血管新生を抑制する2011
- Author(s)
  和氣秀徳、森秀治、劉克約、高橋英夫、西堀正洋
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] AGE-2 and AGE-3 induce monocyte activation.2011
- Author(s)
  Hideo Kohka Takahashi, Shuji Mori, Atsuko Niwa, Masaki Tabuchi, Kyoko Nakamura, Kana Ohshima, Masahiro Nishibori，
- Organizer
  第19回国際マクロファージ分子細胞生物学シンポジウム合同開催国際会議・第76回日本インターフェロン・サイトカイン学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23659687
[Presentation] 抗HMGB1単クローン抗体によるラットMCAO誘発脳梗塞の治療2011
- Author(s)
  西堀正洋
- Organizer
  第47回高血圧関連疾患モデル学会学術総会
- Place of Presentation
  北海道大学学術交流会館
- Year and Date
  2011-09-06
- Data Source
  KAKENHI-PROJECT-21390071
[Presentation] 高ヒスチジン糖タンパク質はHMGB1-ヘパリン複合体誘導血管新生を抑制する2011
- Author(s)
  和氣秀徳, 森秀治, 劉克約，高橋英夫, 西堀正洋
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23659687
[Presentation] Early translocation and release of HMGB1 in ischemic brain in rats2011
- Author(s)
  劉克約, 張継勇, 和氣秀徳, 高橋英夫, 森秀治, 西堀正洋
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-03-22
- Data Source
  KAKENHI-PROJECT-21659141
[Presentation] 脳虚血早期におけるHMGB1の動態2011
- Author(s)
  劉克約, 西堀正洋, 他4名
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  神奈川,パシフィコ横浜
- Year and Date
  2011-03-22
- Data Source
  KAKENHI-PROJECT-21390071
[Presentation] 抗HMGB1単クローン抗体はラット脳虚血による血液-脳関門の破錠を制御する2011
- Author(s)
  西堀正洋, 張継勇, 劉克約,和氣秀徳, 高橋英夫, 森秀治,大塚愛二
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23659687
[Presentation] HRGのHMGB1－ヘパリン複合体誘導性血管新生調節機構2011
- Author(s)
  和氣秀徳, 森秀治, 高橋英夫, 西堀正洋
- Organizer
  第120回日本薬理学会近畿部会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23659687
[Presentation] 抗体医薬による血管疾患治療と創薬プラットホーム2011
- Author(s)
  西堀正洋
- Organizer
  岡山脳研究セミナー
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23659687
[Presentation] HRGのHMGB1-ヘパリン複合体誘導性血管新生調節機構2011
- Author(s)
  和氣秀徳、森秀治、高橋英夫、西堀正洋
- Organizer
  第120回日本薬理学会近畿部会
- Place of Presentation
  ホテルグランヴィア京都(京都)
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] 抗体医薬による血管疾患治療と創薬プラットホーム2011
- Author(s)
  西堀正洋
- Organizer
  岡山脳研究セミナー
- Place of Presentation
  岡山大学医学部記念会館2F
- Year and Date
  2011-06-25
- Data Source
  KAKENHI-PROJECT-21390071
[Presentation] Early translocation and release of HMGB1 in ischemic brain in rats2011
- Author(s)
  劉克約, 張継勇, 和氣秀徳, 高橋英夫, 森秀治, 西堀正洋
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-03-22
- Data Source
  KAKENHI-PROJECT-21390071
[Presentation] 抗HMGB1単クローン抗体による虚血性脳障害の治療2011
- Author(s)
  西堀正洋
- Organizer
  第12回日本分子脳神経外科学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-10-14
- Data Source
  KAKENHI-PROJECT-21390071
[Presentation] 抗HMGB1抗体は脳虚血誘発性の血液-脳関門破綻を防ぐ2011
- Author(s)
  劉克約，張継勇, 和氣秀徳, 大塚愛二，森秀治, 高橋英夫,西堀正洋
- Organizer
  第119回日本薬理学会近畿部会
- Place of Presentation
  愛知
- Data Source
  KAKENHI-PROJECT-23659687
[Presentation] Anti-HMGB1 monoclonal antibody protects BBB from ischemia-induced disruption in rats2011
- Author(s)
  西堀正洋
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-21390071
[Presentation] 抗HMGB1単クローン抗体はラット脳虚血による血液-脳関門の破錠を制御する2011
- Author(s)
  西堀正洋
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-21390071
[Presentation] Disruption of BBB in rat MCAO and a protective effect of anti-HMGB1 antibody2010
- Author(s)
  Liu K, Nishibori M
- Organizer
  16^<th> World Congress on Basic and Clinical Pharmacology
- Place of Presentation
  Bella Center Copenhagen, Denmark
- Year and Date
  2010-07-19
- Data Source
  KAKENHI-PROJECT-21390071
[Presentation] 脳虚血早期におけるHMGB1の動態2010
- Author(s)
  劉克約, 張継勇, 和氣秀徳, 高橋英夫, 森秀治, 西堀正洋
- Organizer
  第118回日本薬理学会近畿部会
- Place of Presentation
  千里ライフサイエンスセンター
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-21390071
[Presentation] AGE-2とAGE-3誘導性のヒト単球の活性化に対するプロスタグランディンE2の効果2010
- Author(s)
  高橋英夫, 劉克約, 和氣秀徳, 森秀治, 西堀正洋
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20590539
[Presentation] Advanced glycation end products induce adhesion molecule expression and cytokine production in human PBMC2010
- Author(s)
  高橋英夫, 劉克約, 和氣秀徳, 森秀治, 西堀正洋
- Organizer
  第14回国際免疫学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590539
[Presentation] 移植術後糖尿病に対するヒスタミンの効果の基礎検討2010
- Author(s)
  高橋英夫, 劉克約, 和氣秀徳, 森秀治, 西堀正洋
- Organizer
  第14回日本ヒスタミン学会
- Place of Presentation
  川崎グランドホテル
- Year and Date
  2010-10-24
- Data Source
  KAKENHI-PROJECT-21390071
[Presentation] 脳虚血早期におけるHMGB1の動態2010
- Author(s)
  劉克約, 張継勇, 和氣秀徳, 高橋英夫, 森秀治, 西堀正洋
- Organizer
  第118回日本薬理学会近畿部会
- Place of Presentation
  千里ライフサイエンスセンター
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-21659141
[Presentation] A novel anti-HMGB1 treatment for brain infarction : protection of BBB disruption2010
- Author(s)
  Nishibori M, 他10名
- Organizer
  The 4^<th> international HMGB1 symposium signals of tissue damage
- Place of Presentation
  Finland
- Year and Date
  2010-06-23
- Data Source
  KAKENHI-PROJECT-21390071
[Presentation] 移植術後糖尿病に対するヒスタミンの効果の基礎検討2010
- Author(s)
  高橋英夫, 劉克約, 和氣秀徳, 森秀治, 西堀正洋
- Organizer
  第14回日本ヒスタミン学会
- Place of Presentation
  川崎グランドホテル
- Year and Date
  2010-10-24
- Data Source
  KAKENHI-PROJECT-21659141
[Presentation] 抗体医薬による血管疾患治療と創薬プラットホーム構築2010
- Author(s)
  西堀正洋
- Organizer
  第130年会日本薬学会
- Place of Presentation
  岡山コンベンションセンター他
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-21390071
[Presentation] Prostaglandins E_2 inhibits advanced glycation end products-induced activation of human monocytes2010
- Author(s)
  高橋英夫, 劉克約, 和氣秀徳, 森秀治, 西堀正洋
- Organizer
  第16回国際薬理学会
- Place of Presentation
  コペンハーゲン
- Data Source
  KAKENHI-PROJECT-20590539
[Presentation] ラット中大脳動脈閉塞・再灌流モデルにおける抗HMGB1単クローン抗体の効果:脳血管透過性亢進に対する影響2010
- Author(s)
  劉克約, 西堀正洋, 他6名
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-21390071
[Presentation] Histamine inhibits advanced glycation end product-induced adhesion molecule expression on monocytes during human mixed lymphocyte reaction.2010
- Author(s)
  張継勇, 高橋英夫, 劉克約, 和氣秀徳, 劉瑞, 森秀治, 西堀正洋
- Organizer
  第117回日本薬理学会近畿部会
- Place of Presentation
  徳島県郷土文化会館
- Year and Date
  2010-07-08
- Data Source
  KAKENHI-PROJECT-21659141
[Presentation] Histamine inhibits advanced glycation end product-induced adhesion molecule expression on monocytes during human mixed lymphocyte reaction.2010
- Author(s)
  張継勇, 高橋英夫, 劉克約, 和氣秀徳, 劉瑞, 森秀治, 西堀正洋
- Organizer
  第117回日本薬理学会近畿部会
- Place of Presentation
  徳島県郷土文化会館
- Year and Date
  2010-07-08
- Data Source
  KAKENHI-PROJECT-21390071
[Presentation] 脳虚血時におけるHMGB1動態の初期変化2009
- Author(s)
  西堀正洋, 他6名
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2009-09-17
- Data Source
  KAKENHI-PROJECT-21390071
[Presentation] 脳虚血時におけるHMGB1動態の初期変化2009
- Author(s)
  西堀正洋
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2009-09-17
- Data Source
  KAKENHI-PROJECT-21659141
[Presentation]2009
- Author(s)
  高橋英夫, 森秀治, 劉克約, 和氣秀徳, 西堀正洋
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590539
[Presentation] HMGB1を標的とした抗体医薬による脳梗塞の新規治療法2009
- Author(s)
  西堀正洋
- Organizer
  第8回国際バイオフォーラム
- Place of Presentation
  東京ビックサイト
- Year and Date
  2009-07-03
- Data Source
  KAKENHI-PROJECT-21390071
[Presentation] A Proatherogenic Role for HMGB1 in Atherosclerosis2009
- Author(s)
  Alex Bobik, Nishibori M, 他8名
- Organizer
  American Heart Association Meeting
- Place of Presentation
  Florida, USA
- Year and Date
  2009-11-18
- Data Source
  KAKENHI-PROJECT-21390071
[Presentation] HMGB1を標的とする脳梗塞の抗体治療2008
- Author(s)
  西堀正洋
- Organizer
  第12回エンドトキシン血症救命治療研究会
- Place of Presentation
  ホテル日航福岡
- Year and Date
  2008-02-28
- Data Source
  KAKENHI-PROJECT-19659061
[Presentation] HMGBl-RAGE系の制御による疾患治療の可能性2008
- Author(s)
  西堀正洋
- Organizer
  第16回糖尿病セミナーUP-TO-DATE
- Place of Presentation
  ホテルグランヴィア岡山
- Year and Date
  2008-09-04
- Data Source
  KAKENHI-PROJECT-19659061
[Presentation] A Novel Antibody drug for the treatment of acute brain infarction.2008
- Author(s)
  西堀正洋
- Organizer
  Thrombolysis and Acute Stroke Therapy 2008
- Place of Presentation
  Sofitel Budapest Hotel
- Year and Date
  2008-09-22
- Data Source
  KAKENHI-PROJECT-19659061
[Presentation] A Novel and effective antibody therapy for brain infarction targeting alarmin/HMGB1.2008
- Author(s)
  西堀正洋
- Organizer
  EHRLICH II-2nd World Conference on Magic Bullets, 2008, Nurnberg, 2008.
- Place of Presentation
  Ceorg-Simon-Ohm-Hochschule fur angewandte Wissenschaften-Fachhochsdhule Murnberg
- Data Source
  KAKENHI-PROJECT-19659061
[Presentation] アラーミン/HMGB1を標的とする新規脳梗塞治療法2008
- Author(s)
  西堀正洋
- Organizer
  第31回日本神経科学大会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2008-07-11
- Data Source
  KAKENHI-PROJECT-19659061
[Presentation] A novel anti-inflammatory transient of acute brain infarction by anti-HMGB1 monoclonal antibody2007
- Author(s)
  西堀正洋(他)
- Organizer
  Neurocience Meeting
- Place of Presentation
  アメリカサンディエゴ
- Year and Date
  2007-11-08
- Data Source
  KAKENHI-PROJECT-19590534
[Presentation] A novel anti-inflammatory transient of acute brain infarction by anti-HMGB1 monoclonal antibody2007
- Author(s)
  西堀正洋, 他
- Organizer
  Neuroscience Meeting 2007
- Place of Presentation
  アメリカサンディエゴ
- Year and Date
  2007-11-08
- Data Source
  KAKENHI-PROJECT-19590534
[Presentation] ラットリンパ節法によるALE特異モノクローナル抗体の作製
- Author(s)
  森岡祐太、大西香織、友野靖子、森秀治、和氣秀徳、劉克約、勅使川原匡、西堀正洋
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（名古屋市）
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] 破骨細胞様細胞の分化培養における非炎症性物質の影響
- Author(s)
  豊村隆男、和氣秀徳、勅使川原匡、劉克約、髙橋英夫、西堀正洋、森秀治
- Organizer
  第87回日本生化学会大会，京都，2014
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24590658
[Presentation] 高ヒスチジン糖タンパク質（HRG）による敗血症治療の可能性
- Author(s)
  和氣秀徳、森秀治、髙橋英夫、劉克約、勅使川原匡、西堀正洋
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-25670464
[Presentation] マクロファージ由来HMGB1はNF-κB系を介して炎症性痛覚過敏に寄与する
- Author(s)
  山岨大智、関由加里、山西広樹、坪田真帆、八木秀樹、益子高、西堀正洋、川畑篤史
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（名古屋市）
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] SIRS患者におけるHistidine-Rich Glycoproteinについて
- Author(s)
  黒田浩佐、森松博史、和氣秀徳、森秀治、西堀正洋
- Organizer
  第42回日本集中治療医学会学術大会
- Place of Presentation
  ホテル日航東京（東京都港区）
- Year and Date
  2015-02-09 – 2015-02-11
- Data Source
  KAKENHI-PROJECT-25670464
[Presentation] 頭部外傷モデルを用いたGlycyrrhizinの神経保護効果の検討
- Author(s)
  大熊佑、劉克約、春間純、高橋英夫、森秀治、西野繁樹、西堀正洋、伊達勲
- Organizer
  日本脳神経外科学会第72回学術総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] DAMPとしてのHMGB1：脳外傷と肺障害
- Author(s)
  大熊佑、劉克約、春間純、高橋英夫、森秀治、西野繁樹、伊達勲、西堀正洋
- Organizer
  第24回日本急性血液浄化学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] 血漿蛋白HRGによる好中球制御と敗血症治療薬開発
- Author(s)
  西堀正洋、和氣秀徳、森秀治
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-25670464
[Presentation] HMGB1結合因子によるAGEs-RAGE結合阻害解析
- Author(s)
  森秀治、和氣秀徳、劉克約、勅使川原匡、高橋英夫、西堀正洋、豊村隆男
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館（京都市）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] ラットリンパ節法によるALE特異モノクローナル抗体の作製
- Author(s)
  森岡祐太、大西香織、友野靖子、森秀治、和氣秀徳、劉克約、勅使川原匡、西堀正洋
- Organizer
  日本薬理学会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] HMGB1結合因子によるAGEs-RAGE結合阻害解析
- Author(s)
  森秀治、和氣秀徳、劉克約、勅使川原匡、髙橋英夫、西堀正洋、豊村隆男
- Organizer
  第87回日本生化学会大会，京都，2014
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24590658
[Presentation] 抗HMGB1抗体による脳外傷の治療
- Author(s)
  西堀正洋
- Organizer
  第3回HMGB1シンポジウム
- Place of Presentation
  松本
- Invited
- Data Source
  KAKENHI-PROJECT-23659687
[Presentation] Voluntary exercise induces neurogenesis in hypothalumus and improves homeostatic functions after stroke
- Author(s)
  丹羽淳子、赤星保光、堀内喜高、濱崎真一、小堀宅郎、西堀正洋、高橋英夫
- Organizer
  第88回日本薬理学会総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-24590337
[Presentation] Histidine-rich glycoprotein prevents septic lethality through neutrophil regulation.
- Author(s)
  Nishibori M, Wake H, Mori S, Liu K, Morioka Y, Teshigawara K, Sakagichi M, Kuroda K, Takahashi H, Ohtsuka A, Yoshino T, Morimatsu H.
- Organizer
  SEPSIS 2014
- Place of Presentation
  Institut Pasteur, Paris, France.
- Year and Date
  2014-12-03 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-25670464
[Presentation] 好中球の制御による敗血症、多臓器不全の治療法開発
- Author(s)
  西堀正洋
- Organizer
  BIO tech 2014 アカデミックフォーラム
- Place of Presentation
  東京ビッグサイト（東京都江東区）
- Year and Date
  2014-05-14 – 2014-05-16
- Data Source
  KAKENHI-PROJECT-25670464
[Presentation] ヒスタミンH2受容体刺激によるHMGB1誘導性免疫応答調節効果の基礎的検討
- Author(s)
  濱崎真一、丹羽淳子、上野浩司、西堀正洋、髙橋英夫
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] Histidine-rich glycoprotein prevents septic lethality through neutrophil regulation.
- Author(s)
  Masahiro Nishibori, Hidenori Wake, Shuji Mori, Keyue Liu, Yuta Morioka, Kiyoshi Teshigawara, Masakiyo Sakaguchi, Kosuke Kuroda, Hideo Takahashi, Aiji Ohtsuka, Tadashi Yoshino, Hiroshi Morimatsu
- Organizer
  Sepsis Symposium
- Place of Presentation
  France, Paris, Pasteur Institute
- Year and Date
  2014-12-03 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] ビンクリスチン誘起神経障害性疼痛ラットにおける抗HMGB1中和抗体と遺伝子組換えヒト可溶性トロンボモジュリンの予防・治療効果
- Author(s)
  西田武司、川石雄大、山西広樹、坪田真帆、関口富美子、石倉宏恭、西堀正洋、川畑篤史
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] グリチルリチンはHMGB1に結合し脳外傷を抑制する
- Author(s)
  春間純、大熊佑、劉克約、和氣秀徳、衷輝、勅使川原匡、伊達勲、西堀正洋
- Organizer
  第１２３回日本薬理学会近畿部会
- Place of Presentation
  ウインク愛知
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] マクロファージによるAdvanced glycation end productsの細胞内取り込み
- Author(s)
  森岡祐太、周京秀、渋谷恵、和氣秀徳、劉克約、勅使川原匡、森秀治、西堀正洋
- Organizer
  日本薬理学会近畿部会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] Massive HMGB1 Release after Hypoxic-Ischemic Brain Injury in Neonatal Rats.
- Author(s)
  Zhang J, Jaitpal S, Stopa EG, Vannucci SJ, Nishibori M, Stonestreet BS.
- Organizer
  2014 PAS/ASPR Joint Meeting
- Place of Presentation
  Vancouver Convention Centre, Vancouver, Canada.
- Year and Date
  2014-05-03 – 2014-05-06
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] Voluntary exercise enhances neurogenesis in hypothalamus after stroke.自発運動は脳卒中後の視床下部神経再生を促進する
- Author(s)
  丹羽　淳子、赤星　保光、堀内　喜高、濱﨑　真一、西堀　正洋、髙橋　英夫
- Organizer
  第87回日本薬理学会
- Place of Presentation
  仙台市
- Data Source
  KAKENHI-PROJECT-24590337
[Presentation] 中和抗体と遺伝子組換えヒト可溶性トロンボモジュリンによるHMGB1不活化はラットおよびマウスにおけるパクリタキセル誘起神経障害性疼痛を抑制する
- Author(s)
  川石雄大、山西広樹、坪田真帆、関口富美子、西田武司、石倉宏恭、西堀正洋、川畑篤史
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] 破骨細胞様細胞の分化培養における非炎症性物質の影響
- Author(s)
  豊村隆男、和氣秀徳、勅使川原匡、劉克約、高橋英夫、西堀正洋、森秀治
- Organizer
  日本生化学会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] ピロカルピン誘発性てんかんモデルマウスにおける抗HMGB-1抗体の効果
- Author(s)
  富麗、劉克約、和氣秀徳、西堀正洋
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（名古屋市）
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] マクロファージによるadvanced glycation end products (AGEs)の細胞内取り込み
- Author(s)
  高遠、森岡祐太、森秀治、和氣秀徳、劉克約、西堀正洋
- Organizer
  第88回日本薬理学会年会，名古屋，2015
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-03-18 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-24590658
[Presentation] 高ヒスチジン糖タンパク質（HRG）の敗血症時血管内好中球流動性に対する効果
- Author(s)
  和氣秀徳、森秀治、高橋英夫、劉克約、勅使川原匡、西堀正洋
- Organizer
  日本薬理学会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] 抗HMGB1抗体の臨床応用と創薬プラットフォーム構築
- Author(s)
  西堀正洋
- Organizer
  イノベーション研究会
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-23659687
[Presentation] 抗HMGB1抗体による脳内出血とクモ膜下出血後の脳血管攣縮治療
- Author(s)
  王登莉、劉克約、西堀正洋
- Organizer
  第88回日本薬理学会年会　シンポジウム，名古屋2015
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-03-18 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-24590658
[Presentation] コラゲナーゼで誘発脳内出血モデルにおける抗HMGB1単クローン抗体の効果
- Author(s)
  劉克約、王登莉、和氣秀徳、勅使川原匡、髙橋英夫、森秀治、西堀正洋
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] High mobility group box 1 as a target for prevention and therapeutic treatment of chemotherapy-induced neuropathic pain.
- Author(s)
  Kawabata A, Kawaishi Y, Nishida T, Yamanishi H, Kamitani N, Tsubota M, Sekiguchi F, Ishikura H, Nishibori M.
- Organizer
  Pharmacology 2014
- Place of Presentation
  Queen Elizabeth II Conference Centre, London, Britain.
- Year and Date
  2014-12-16 – 2014-12-18
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] HMGB1を標的とする脳血管疾患の抗体治療法開発
- Author(s)
  西堀正洋
- Organizer
  第22回脳血管シンポジウム
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-23659687
[Presentation] Plasma levels of Histidine-Rich Glycoprotein in Critically Ill Patients.
- Author(s)
  Kuroda K, Morimatsu H, Wake H, Mori S, Nishibori M.
- Organizer
  IARS 2015 Annual meeting and International Science Symposium
- Place of Presentation
  The Hilton Hawaiian Village – Honolulu, Hawaii, USA.
- Year and Date
  2015-03-21 – 2015-03-24
- Data Source
  KAKENHI-PROJECT-25670464
[Presentation] 好中球活性化制御に着目した敗血症病態解析と治療法開発
- Author(s)
  和氣秀徳、森秀治、高橋英夫、劉克約、勅使川原匡、西堀正洋
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館（京都市）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25670464
[Presentation] グリチルリチンはHMGB1に結合し脳外傷を抑制する
- Author(s)
  春間純、大熊佑、劉克約、和氣秀徳、衷輝、勅使川原匡、伊達勲、西堀正洋
- Organizer
  日本薬理学会近畿部会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] ピロカルピン誘発性てんかんモデルマウスにおける抗HMGB-1抗体の効果
- Author(s)
  富麗、劉克約、和氣秀徳、西堀正洋
- Organizer
  第88回日本薬理学会年会，名古屋，2015
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-03-18 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-24590658
[Presentation] 高ヒスチジン糖タンパク質(HRG)の敗血症時血管内好中球流動性に対する効果
- Author(s)
  和氣秀徳、森秀治、高橋英夫、劉克約、勅使川原匡、西堀正洋
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（名古屋市）
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-25670464
[Presentation] マクロファージによるadvanced glycation end products (AGEs)の細胞内取り込み
- Author(s)
  高遠、森岡祐太、森秀治、和氣秀徳、劉克約、西堀正洋
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（名古屋市）
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] Anti-HMGB1 Antibody Therapy for Brain Ischemia, Brain Injury and Neuropathic Pain
- Author(s)
  Nishibori M, Liu K, Takahashi HK, Mori S.
- Organizer
  International Drug Development Science & Technology
- Place of Presentation
  Tongli Lakeview Hotel, Suzhou, China
- Year and Date
  2014-11-18 – 2014-11-20
- Data Source
  KAKENHI-PROJECT-24590658
[Presentation] 抗HMGB1抗体による脳内出血とクモ膜下出血後の脳血管攣縮治療
- Author(s)
  王登莉、劉克約、西堀正洋
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（名古屋市）
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] Histidine-rich glycoprotein prevents septic lethality through neutrophil regulation
- Author(s)
  Nishibori M, Wake H, Mori S, Liu K, Morioka Y, Teshigawara K, Sakagichi M, Kuroda K, Takahashi H, Ohtsuka A, Yoshino T, Morimatsu H
- Organizer
  SEPSIS 2014
- Place of Presentation
  Institut Pasteur, Paris, France
- Year and Date
  2014-12-03 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-24590658
[Presentation] 好中球活性化制御に着目した敗血症病態解析と治療法開発
- Author(s)
  和氣秀徳、森秀治、髙橋英夫、劉克約、勅使川原匡、西堀正洋
- Organizer
  第87回日本生化学会大会，京都，2014
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24590658
[Presentation] 好中球活性化制御に着目した敗血症病態解析と治療法開発
- Author(s)
  和氣秀徳、森秀治、高橋英夫、劉克約、勅使川原匡、西堀正洋
- Organizer
  日本生化学会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] 遺伝子組換えヒト可溶性トロンボモジュリンはHMGB1シグナルを抑制することでパクリタキセル誘起神経障害性疼痛モデルにおいて予防および治療効果を示す
- Author(s)
  川石雄大、山西広樹、坪田真帆、西堀正洋、石倉宏恭、川畑篤史
- Organizer
  第１２３回日本薬理学会近畿部会
- Place of Presentation
  ウインク愛知
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] Anti-HMGB1 Monoclonal Antibody Therapy for Traumatic Brain Injury in Rats.
- Author(s)
  Nishibori M, Okuma Y, Liu K, Wake H, Maruo T, Teshigawara K, Yamamoto Y, Yamamoto H, Ohtsuka A, Yoshino T, Otani N, Tomura S, Shima K, Takahashi H, Date I, Mori S.
- Organizer
  Merinoff World Congress 2013：HMGB1
- Place of Presentation
  Feinstein Institute for Medical Research, New York, USA.
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] Anti-HMGB1 Antibody Therapy for Brain Ischemia, Brain Injury and Neuropathic Pain.
- Author(s)
  Nishibori M, Liu K, Takahashi HK, Mori S.
- Organizer
  International Drug Development Science & Technology 2014
- Place of Presentation
  Tongli Lakeview Hotel, Suzhou, China.
- Year and Date
  2014-11-18 – 2014-11-20
- Data Source
  KAKENHI-PROJECT-24390061
[Presentation] The inhibitory effect of histamine on high mobility group box 1 activity via the cAMP/PKA pathway.ヒスタミンH2受容体刺激によるHMGB1誘導性免疫応答調節効果の基礎的検討
- Author(s)
  濱崎真一、丹羽　淳子、上野　浩司、西堀　正洋、髙橋　英夫
- Organizer
  第87回日本薬理学会
- Place of Presentation
  仙台市
- Data Source
  KAKENHI-PROJECT-24590337
[Presentation] 抗High Mobility Group Box-1抗体による脳梗塞、脳外傷、脳血管攣縮治療
- Author(s)
  西堀正洋
- Organizer
  生体機能と創薬シンポジウム2012
- Place of Presentation
  神戸
- Invited
- Data Source
  KAKENHI-PROJECT-23659687
[Presentation] HMGB1結合因子によるAGEs-RAGE結合阻害解析
- Author(s)
  森秀治、和氣秀徳、劉克約、勅使川原匡、高橋英夫、西堀正洋、豊村隆男
- Organizer
  日本生化学会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25460649
[Presentation] 新しい炎症制御機序と対外循環
- Author(s)
  西堀正洋
- Organizer
  第59回日本透析医学会学術集会・総会
- Place of Presentation
  神戸ポートピアホテル（神戸市）
- Year and Date
  2014-06-12 – 2014-06-15
- Invited
- Data Source
  KAKENHI-PROJECT-25670464
[Presentation] 自発運動は視床下部神経新生を促進し脳卒中後の恒常性維持に寄与する
- Author(s)
  丹羽淳子、赤星保光、堀内喜高、濱崎真一、小堀宅郎、西堀正洋、高橋英夫
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（名古屋市）
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-24390061

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Nishibori Masahiro 西堀 正洋

NISHIBORI Masahiro 西堀 正洋

西堀 正洋 ニシボリ マサヒロ

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Analysis dynamics of HMGB1 as a biosensor molecule and its multiple functionsPrincipal Investigator

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Mechanism for microthrombus formation on NETosis and development of therapy for ARDS.Principal Investigator

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Nishibori Masahiro 西堀正洋

NISHIBORI Masahiro 西堀正洋

西堀正洋ニシボリマサヒロ