INOUE Osamu 井上修

… Alternative Names

渡辺恭良ワタナベヤスヨシ

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Researcher Number	50159969
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2013: 大阪大学, 医学(系)研究科(研究院), 特任教授 2011 – 2012: 大阪大学, 医学(系)研究科(研究院), 教授 2009: Osaka University, 大学院・医学系研究科, 教授 2003 – 2009: 大阪大学, 医学系研究科, 教授 2007: 独立行政法人放射線医学総合研究所, 大阪大学・医学研究科, 教授 … More 2004: Osaka University, Graduate School of Medicine, Professor, 大学院・医学系研究科, 教授 1997 – 2002: 大阪大学, 医学部, 教授 1993 – 1996: 放射線医学総合研究所, 障害臨床研究部, 室長 1995: (財)大阪バイオサイエンス研究所, 第3研究部, 研究部長 1992: 放射線医学総合研究所, 臨床研究部, 主任研究官 Less
Review Section/Research Field	Principal Investigator Radiation science / Radiation science / Physical pharmacy Except Principal Investigator Radiation science / Environmental physiology (including Physical medicine and Nutritional physiology) / Physical pharmacy / Circulatory organs internal medicine / General medical chemistry / Psychiatric science / Biological Sciences / Pathological medical chemistry
Keywords	Principal Investigator cAMP / PET / グリア細胞 / NO / MK-801 / c-AMP / インビトロ / インビボ / 興奮性アミノ酸 / Rat … More / Monocarboxylate transporter / Glial cell / Excitatory amino acid / Cerebral ischemia / ^<14>C-acetate / ^<14>-酢酸 / ラット / モノカルボン酸トランスポーター / 脳虚血 / ^<14>C-酢酸 / in vitro / in vivo / receptor binding / インビドロ / 受容体結合 / functional image / kon, koff / benzodiazepin / muscarinic acetylcholone / dopamine / 速度定数 / SPECT / ベンゾジアセピン / アセチルコリン / 受容体 / 生体脳 / Rolipram / Raclopride / NMSP / レセプター / 生体脳(インビボ) / cooperativity / 結合速度因子 / イオマゼニール / フルマゼニール / 代謝画像 / N^<13>-アンモニア / 機能画像 / kon、koff / ベンゾジアゼピン / ムスカリン性アセチルコリン / ドーパミン / status epilepsy / developing / washout rate / protracer / glia / Benzyl acetate / 生理活性 / イメージング / 放射線 / 神経科学 / ストレス誘発性 / 超微量 / 拮抗剤 / ポジトロン核種 / ポジトロン / diprenorphine / 鎮痛作用 / モルヒネ / 超高比放射能 / 14C-酢酸 / 神経保護作用 / 脳血流 / 糖代謝 / 酸素代謝 / ミクログリア / キノリン酸 / NMDA / PK11195 / ^<18>F-FEDAC / 脂肪族ケトン体 / PETプローブ用マイクロダイアリシス法 / Ro5-4864 / PK-11195 / 心筋 / 末梢性BZ受容体 … More Except Principal Investigator MRI / PET / SPECT / ベンゾジアゼピン受容体 / acetate / Tc-99m HMPAO / 酢酸 / fMRI / Positron emission tomography / ポジトロン / 薬物動態 / ポジトロンエミッショントモグラフィー / diphenylhydantoin / myocardium / positron / ion channel / ナトリウムイオンチャンネル / diphenylhidantoin / 心筋 / イオンチャネル / Nano-device / Magnetic resonance imaging / Microdialysis / Liauid chromatography / Imaging / Bioactivity / Brain and Neuron / Analytical Chemistry / 分析科学 / ナノデバイス / 微小透析 / HPLC / イメージング / 生理活性 / 脳・神経 / 分析化学 / fuzzy clustering / Bayesian image reconstruction method / anatomical information / partial volume effect / ^<99m>Tc HMPAO / ファジークラスタリング / ベイーズの画像再構成法 / 解剖学的情報 / 部分容積効果 / Pharmacokinetics / Glia / Acetate / Brain tumor / Brain infarction / Glucose metabolism / Cancer / ^<18>FDG / Phosgene / 悪性腫瘍 / ホスゲン / アミノ酸代謝 / 薬物体内動態 / グリア / 脳腫瘍 / 脳梗塞 / ブドウ糖代謝 / Amygdula / human / Behavior Thermoregulation / Temperature / Emotion / 寒さ / 暑さ / 条件付け学習 / 温熱的情動感覚 / 扁桃核 / ヒト / 行動性体温調節 / 温度 / 情動 / perfusion / Contrast media / Circulation / Ischemic Heart Disease / Ultrasound / 冠循環 / 弗素ガス / 気泡 / 造影剤 / 超音波 / Skin vasomotion / Shivering / Nonshivering thermogenesis / Autonomous distributing system / Thermoregulation / Hypothalamus / 皮膚血管運動 / ふるえ / 非ふるえ熱産生 / 自律分散システム / 体温調節 / 視床下部 / Adrenal chromaffine cells / Radio-LC-MS / Metapyrocatechase / Oxygen sensor / Oxygenase / Oxygen metabolism / Oxygen-15 / Positron emitter / 副腎クロムアフィン細胞 / ラジオLC-MS / メタピロカテカ-ゼ / 酸素センサー / 酸素添加酵素 / 酸素代謝 / 酸素-15 / ポジトロン放出核種 / Brain ischemia model / Schizophrenia / Infantile antism / Glutamate system / Dopamine D_2 receptor / Dopamine turnover / Dopaminergic system / 睡眠-覚醒 / 麻酔 / イオンチャンネル / ムスカリン性アセチルコリン受容体 / ^<11>C-5-ヒドロキシトリプトファン / ^<11>C-ドーバ / ペンゾジアゼピン系 / GABA系 / アセチルコリン系 / 麻酔剤 / 脳虚血モデル / 精神分裂症 / 小児自閉症 / グルタミン酸系 / ドーパミンD2受容体 / ドーパミン代謝回転 / ドーパミン系 / ホジトロンエミッショントモグラフィー / 脳 / マイクロドージング / Iomazenil / ECT / 局所脳血流測定 / 脳酢酸取り込み / グリア活性 / 脳血流 / SPEC / 電気けいれん療法 / うつ病 / 最適標識合成条件 / 早期画像 / 高次脳機能 / 腸管 / bFGF / 集積率 / 悪性黒色種 / 標識リガンド / 外部計測 / 不均質感受性 / 腫瘍誘発 / 線量-効果 / 細胞周期 / 遺伝子発現 / 画像診断 / 染色体 / 低酸素 / 遺伝子 / 感受性 / 放射線生物 / 癌治療 / 重粒子線 / ネコ / 外側膝状体 / 線条皮質 / 発達 / シナプス可塑性 / 眼優位カラム / カイニン酸 / サブプレート / ドーパミンD_2受容体 / ^<11>C-N-メチルスピペロン / テトラハイドロバイオプテリン / ^<11>C-ドーパ(DOPA) / アカゲザル / 芳香族アミノ酸脱炭酸酵素 / セロトニン遊離 / ^<11>C-5-ヒドロキシ-L-トリプトファン / ドーパミン遊離 / L-^<11>C-ドーパ(DOPA) / 神経伝達物質 Less

Evaluation of 14C(11C)-Benzyl acetate as a potential probe for the measurement of glial metabolism.Principal Investigator
- Principal Investigator
  
  INOUE Osamu
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Osaka University
Study on functional roles of PBR (TSPO) in glia and myocardiumPrincipal Investigator
- Principal Investigator
  
  INOUE Osamu
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Osaka University
Evaluation of brain and whole-body micro-dosing pharmacokinetics of <11>^C-labeled donepezil in rats by means of planar positron imaging system
- Principal Investigator
  
  SHIMOSEGAWA Eku
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Osaka University
超高比放射能標識リガンドによる生体超微量現象の解明Principal Investigator
- Principal Investigator
  
  井上修
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  Osaka University
Changes in brain functional images by the electroconvulsive therapy on severe depressive patients
- Principal Investigator
  
  KOBAYASHI Kaoru
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  University of Yamanashi
Imaging of Na^+ion channel in myocardium by means of Positron Planar Imaging system with ^<11>C-diphenylhidantion
- Principal Investigator
  
  HATAZAWA Jun
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Osaka University
重粒子線治療の生物学
- Principal Investigator
  
  古澤佳也, 安藤興一
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Radiological Sciences
An invention of the probes "antibody bound magnetism nanoparticles" for the macromolecule measurement in the brain, and the practical use to the brain function researches
- Principal Investigator
  
  YAMAGUCHI Masatoshi
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Fukuoka University
Development of RI probe for the measurement of glial metabolism.Principal Investigator
- Principal Investigator
  
  INOUE Osamu
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Osaka University
Positron Emission Tomography for Integrated Biomedical Monitoring System
- Principal Investigator
  
  HATAZAWA Jun
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Osaka University
Correction of partial volume effect in SPECT/PET using anatomical information
- Principal Investigator
  
  MURASE Kenya
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Osaka University
Development of receptor activation method for brain imaging with PET or SPECTPrincipal Investigator
- Principal Investigator
  
  INOUE Osamu
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Osaka University
Systems for analysing thermal emotion (behavioral thermoregulation)
- Principal Investigator
  
  KANOSUE Kazuyuki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Osaka University
Skill of intravenous ultrasonic contrast agent for evaluation of microcirculation of human organs and its assessment for clinical use.
- Principal Investigator
  
  BEPPU Shintaro
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University
Examination of the hyposesis of thermoredulatory module in the hypothalamus.
- Principal Investigator
  
  KANOSUE Kazuyuki
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Osaka University
Study on the new functional neurotransmision image with PET in intact brainPrincipal Investigator
- Principal Investigator
  
  INOUE Osamu
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Osaka University
神経活動に依存した大脳皮質視覚野機能構築の細胞・分子機構
- Principal Investigator
  
  今村一之
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka Bioscience Institute
Development of novel techniques for analysis of oxygen metabolism and oxygen-sensing mechanisms by use of positron-emitter oxygen-15
- Principal Investigator
  
  WATANABE Yasuyoshi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka Bioscience Institute
ポジトロンエミッショントモグラフィーを用いた神経伝達物質遊離の無侵襲的定量解析
- Principal Investigator
  
  WATANABE Yasuyoshi (渡邊恭良)
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka Bioscience Institute
Turnover of neurotransmitters in the living and functional brain analized by positron emission Tomography
- Principal Investigator
  
  WATANABE Yasuyoshi, 渡邊恭良
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Osaka Bioscience Institute

All 2013 2012 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation

[Journal Article] Improvement of brain uptake for in vivo PET imaging of astrocytic oxidative metabolism using benzyl [1-11C]acetate.2013
- Author(s)
  OKADA Maki, NAKAO Ryuji, MOMOSAKI Sotaro, YANAMOTO Kazuhiko, KIKUCHI Tatsuya, OKAMURA Toshimitsu, WAKIZAKA Hidekatsu, HOSOI Rie, ZHANG Ming-Rong, INOUE Osamu.
- Journal Title
  
  Applied Radiation and Isotopes
  
  Volume: 78 Pages: 102-107
- DOI
  10.1016/j.apradiso.2013.04.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591767
[Journal Article] In vivo imaging and quantitative analysis of TSPO in rat peripheral tissues using small-animal PET with [18F]FEDAC.2010
- Author(s)
  Yanamoto K, Kumata K, Fujinaga M, Nengaki N, Takei M, Wakizaka H, Hosoi R, Momosaki S, Yamasaki T, Yui J, Kawamura K, Hatori A, Inoue O, Zhang MR
- Journal Title
  
  Nucl Med Biol (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390319
[Journal Article] PK11195 might selectively suppress the quinolinic acid-induced enhancement of anaerobic glycolysis in glial cells.2010
- Author(s)
  Momosaki S, Imamoto N, Hosoi R, Sawada Y, Abe K, Zhang MR, Inoue O
- Journal Title
  
  Brain Res (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390319
[Journal Article] Inhibitory effect of methyl ethyl ketone upon the enhancement of cerebral blood flow during status epilepticus induced by lithiumpilocarpine.2009
- Author(s)
  Sugiyama E, Matsuki Y, Momosaki S, Hosoi R, Hasebe N, Abe K, Inoue O
- Journal Title
  
  Neurosci Lett 462(3)
  
  Pages: 300-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390319
[Journal Article] De-coupling of blood flow and metabolism in the rat brain induced by glutamate.2009
- Author(s)
  Hirose S, Momosaki S, Sasaki K, Hosoi R, Abe K, Gee A, Inoue O
- Journal Title
  
  Ann Nucl Med. 23(3)
  
  Pages: 293-300
- NAID
  10025136159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390319
[Journal Article] Role of NMDA receptor upon [14C]acetate uptake into intact rat brain.2009
- Author(s)
  Hirose S, Momosaki S, Hosoi R, Abe K, Gee A, Inoue O
- Journal Title
  
  Ann Nucl Med 23(2)
  
  Pages: 143-7
- NAID
  10025135668
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390319
[Journal Article] De-coupling of blood flow and metabolism in the rat brain induced by glutamate.2009
- Author(s)
  Hirose S, Momosaki S, Sasaki K, Hosoi R, Abe K, Gee A, Inoue O
- Journal Title
  
  Ann Nucl Med 23(3)
  
  Pages: 293-300
- NAID
  10025136159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390319
[Journal Article] Evaluation of N-benzyl-N-[^<11>C]methyl-2- (7-methyl-8-oxo-2-phenyl-7,8-dihydro-9H-purin-9-yl)acetamide ([^<11>C]DAC) as a novel translocator protein (18 kDa) radioligand in kainic acid-lesioned rat.2009
- Author(s)
  Yanamoto K, Yamasaki T, Kumata K, Yui J, Odawara C, Kawamura K, Hatori A, Inoue O, Yamaguchi M, Suzuki K, Zhang MR.
- Journal Title
  
  Synapse. 63(11)
  
  Pages: 961-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390319
[Journal Article] Methyl ethyl ketone blocks status epilepticus induced by lithium-pilocarpine in rats.2009
- Author(s)
  Inoue O, Sugiyama E, Hasebe N, Tsuchiya N, Hosoi R, Yamaguchi M, Abe K, Gee A
- Journal Title
  
  Br J Pharmacol 158(3)
  
  Pages: 872-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390319
[Journal Article] Evaluation of N-benzyl-N-[11C] methyl-2-(7-methyl-8-oxo-2-phenyl-7, 8-dihydro-9H-purin-9-yl)acetamide ([11C]DAC) as a novel translocator protein (18 kDa) radioligand in kainic acid-lesioned rat.2009
- Author(s)
  Yanamoto K, Yamasaki T, Kumata K, Yui J, Odawara C, Kawamura K, Hatori A, Inoue O, Yamaguchi M, Suzuki K, Zhang MR
- Journal Title
  
  Synapse 63(11)
  
  Pages: 961-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390319
[Journal Article] In vivo monitoring of extracellular 13N-glutamine derived from bloodborne 13N-ammonia in rat striatum using microdialysis with radio-LC method.2009
- Author(s)
  Okada M, Nakao R, Hosoi R, Zhang MR, Fukumura T, Suzuki K, Inoue O
- Journal Title
  
  J Neurosci Methods 184(1)
  
  Pages: 37-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390319
[Journal Article] In vivo monitoring of extracellular ^<13>N-glutamine derived from blood-borne ^<13>N-ammonia in rat striatum using microdialvsis with radio-LC method.2009
- Author(s)
  Okada M, Nakao R, Hosoi R, Zhang MR, Fukumura T, Suzuki K, Inoue O.
- Journal Title
  
  J Neurosci Methods. 184(1)
  
  Pages: 37-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390319
[Journal Article] Methyl ethyl ketone blocks status epilepticus induced by lithium-pilocarpine in rats.2009
- Author(s)
  Inoue O, Sugiyama E, Hasebe N, Tsuchiya N, Hosoi R, Yamaguchi M, Abe K, Gee A.
- Journal Title
  
  Br J Pharmacol. 158(3)
  
  Pages: 872-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390319
[Journal Article] Effect of PK11195 on attenuating the enhancement of glucose utilization induced by quinolinic acid infusion in the rat brain2008
- Author(s)
  Amitani M, Ohashi A, Hatazawa J, Gee A, Inoue O
- Journal Title
  
  Synapse 62
  
  Pages: 253-258
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591416
[Journal Article] Effect of PK11195 on attenuating the enhancement of glucose utilization induced by quinolinic acid infusion in the rat brain.2008
- Author(s)
  Amitani M, Ohashi A, Hatazawa J, Gee A, Inoue O
- Journal Title
  
  Synapse 62(4)
  
  Pages: 253-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390319
[Journal Article] Combining high-performance liquid chromatography-positron detection and on-line microdialysis for animal metabolism study of positron emission tomography probes.2008
- Author(s)
  Nakao R, Okada M, Inoue O, Fukumura T, Suzuki K
- Journal Title
  
  J Chromatogr A 1203(2)
  
  Pages: 193-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390319
[Journal Article] Role of NMDA receptors in the increase of glucose metabolism in the rat brain induced by fluorocitrate2007
- Author(s)
  S.Hirose, Y.Umetani, M.Amitani, R.Hosoi, S.Momosaki, J, Hatazawa, A.Gee, O.Inoue
- Journal Title
  
  Neuroscience Letters 415
  
  Pages: 259-263
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390013
[Journal Article] Role of NMDA receptors in the increase of glucose metabolism in the rat brain induced by fluorocitrate2007
- Author(s)
  S.Hirose, Y.Umetani, M.Amitani, R.Hosoi, S.Momosaki, J.Hatazawa, A.Gee, O.Inoue
- Journal Title
  
  Neuroscience Letters 415
  
  Pages: 259-263
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390013
[Journal Article] Sensitive Reduction in ^<14>C-acetate Uptake in a Short-term Ischemic Rat Brain2007
- Author(s)
  R.Hosoi, Y.Kashiwagi, M.Tokumura, K.Abe, J.Hatazawa, O.Inoue
- Journal Title
  
  Joumal of Stroke and Cerebrovascular Diseases 16
  
  Pages: 77-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390013
[Journal Article] Sensitive reduction in ^<14>C-acetate uptake in a short-term ischemic rat brain2007
- Author(s)
  R. Hosoi, Y. Kashiwagi, M. Tokumura, K. Abe, J. Hatazawa, O. Inoue
- Journal Title
  
  Journal of Stroke and Cerebro vascular Diseases 16
  
  Pages: 77-81
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390013
[Journal Article] Sensitive reduction in ^<14>C-acetate uptake in a short-term ischemic rat brain2007
- Author(s)
  R.Hosoi, Y.Kashiwagi, M.Tokumura, K.Abe, J.Hatazawa, O.Inoue
- Journal Title
  
  Journal of Stroke and Cerebrovascular Diseases 16
  
  Pages: 77-81
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390013
[Journal Article] Role of NMDA receptors in the increase of glucose metabolism in the rat brain induced by fluorocitrate2007
- Author(s)
  S. Hirose, Y. Umetani, M. Amitani, R. Hosoi, S. Momosaki, J. Hatazawa, A. Gee, O. Inoue
- Journal Title
  
  Neuroscience Letters 415
  
  Pages: 259-263
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390013
[Journal Article] [^<14>C]Benzyl acetate is a potential radiotracer for the measurement of glial metabolism in the rat brain2007
- Author(s)
  S.Momosaki, R.Hosoi, T.Sanuki, K.Todoroki, M.Yamaguchi, A.Gee, O.Inoue
- Journal Title
  
  Nuclear Medicine and Biology 34
  
  Pages: 939-944
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390013
[Journal Article] [^<14>C]jBenzyl acetate is a potential radiotracer for the measurement of glial metabolism in the rat brain2007
- Author(s)
  S. Momosaki, R. Hosoi, T. Sanuki, K. Todoroki, M. Yamaguchi, A. Gee, O. Inoue
- Journal Title
  
  Nuclear Medicine and Biology 34
  
  Pages: 939-944
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390013
[Journal Article] Evaluation of [^<14>C]phenylacetate as a prototype tracer for the measurement of glial metabolism in the rat brain.2006
- Author(s)
  Inoue O
- Journal Title
  
  Nuclear Medicine and Biology 33(8)
  
  Pages: 985-989
- Data Source
  KAKENHI-PROJECT-16390339
[Journal Article] Evaluation of [^<14>C] phenylacetate as a prototype tracer for the measurement of glial metabolism in the rat brain2006
- Author(s)
  O.Inoue, R.Hosoi, S.Momosaki, K.Yamamoto, M.Amitani, M.Yamaguchi, A.Gee
- Journal Title
  
  Nuclear Medicine and Biology 33(8)
  
  Pages: 985-989
- Data Source
  KAKENHI-PROJECT-17390013
[Journal Article] Evaluation of [^<14>C]phenylacetate as a prototype tracer for the measurement of glial metabolism in the rat brain.2006
- Author(s)
  Inoue O
- Journal Title
  
  Nucl Med Biol. 33(8)
  
  Pages: 985-989
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390339
[Journal Article] Evaluation of[^<14>C]phenylacetate as a prototype tracer for the measurement of glial metabolism in the rat brain2006
- Author(s)
  0. Inoue, R. Hosoi, S. Momosaki, K. Yamamoto, M. Amitani, M. Yamaguchi, A. Gee
- Journal Title
  
  Nuclear Medicine and Biology 33
  
  Pages: 985-989
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390013
[Journal Article] Glial metabolic dysfunction caused neural damage by short-term ischemia in brain2006
- Author(s)
  R. Hosoi, Y. Kashiwagi, J. Hatazawa, A. Gee, O. Inoue
- Journal Title
  
  Annals of Nuclear Medicine 20
  
  Pages: 377-380
- NAID
  10018775728
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390013
[Journal Article] Evaluation of [^<14>C]phenylacetate as a prototype tracer for the measurement of glial metabolism in the rat brain2006
- Author(s)
  O.Inoue, R.Hosoi, S.Momosaki, K.Yamamoto, M.Amitani, M.Yamaguchi, A.Gee
- Journal Title
  
  Nuclear Medicine and Biology 33
  
  Pages: 985-989
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390013
[Journal Article] Glialmetabolicdysfunction caused neural damage by short-temischemia in brain2006
- Author(s)
  R.Hosoi, Y.Kashiwagi, J.Hatazawa, A.Gee, O.Inoue
- Journal Title
  
  Annals of Nuclear Medicine 20(5)
  
  Pages: 377-380
- Data Source
  KAKENHI-PROJECT-17390013
[Journal Article] Evaluation of [^<14>C] phenylacetate as a prototype tracer for the measurement of glial metabolism in the rat brain.2006
- Author(s)
  Inoue O
- Journal Title
  
  Nucl Med Biol. 33(8)
  
  Pages: 985-989
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390339
[Journal Article] Blood flow dependence of the intratumoral distribution of peripheral benzodiazepine receptor binding in intact mouse fibrosarcoma2006
- Author(s)
  Amitani M, Zhang MR, Noguchi J, Kumata K, Ito T, Takai N, Suzuki K, Hosoi R, Inoue O
- Journal Title
  
  Nucl Med Biol 33
  
  Pages: 971-975
- Data Source
  KAKENHI-PROJECT-17016083
[Journal Article] The apparent positive cooperativity of in vivo [3H]PK-11195 binding in mouse fibrosarcoma.2006
- Author(s)
  Momosaki S, Hosoi R, Takai N, Gee A, Inoue O
- Journal Title
  
  Nucl Med Biol 33
  
  Pages: 797-800
- Data Source
  KAKENHI-PROJECT-17016083
[Journal Article] Glial metabolic dysfunction caused neural damage by short-term ischemia in brain2006
- Author(s)
  R.Hosoi, Y.Kashiwagi, J.Hatazawa, A.Gee, O.Inoue
- Journal Title
  
  Annals of Nuclear Medicine 20
  
  Pages: 377-380
- NAID
  10018775728
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390013
[Journal Article] Distinct different intra-tumor distribution of FDG between early phase and late phase in mouse fibrosacroma.2005
- Author(s)
  Inoue O et al.
- Journal Title
  
  Ann Nucl Med. 19(8)
  
  Pages: 655-659
- Data Source
  KAKENHI-PROJECT-15390361
[Journal Article] Distinct different intra-tumor distribution of FDG between early phase and late phase in mouse fibrosarcoma.2005
- Author(s)
  Inoue O
- Journal Title
  
  Ann Nucl Med. 19(8)
  
  Pages: 655-659
- NAID
  10017673263
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390339
[Journal Article] Distinct different intra-tumor distribution of FDG between early phase and late phase in mouse fibrosarcoma.2005
- Author(s)
  Inoue O et al.
- Journal Title
  
  Ann Nucl Med. 19(8)
  
  Pages: 655-659
- NAID
  10017673263
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390361
[Presentation] [^<14>C]Benzyl Acetateの脳内動態の測定とその解析2012
- Author(s)
  香川智彦、吉野恵子、柳本和彦、細井理恵、木村敦臣、井上修、岡田真希、張明栄
- Organizer
  第12回放射性医薬品・画像診断薬研究会
- Place of Presentation
  京都
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-23591767
[Presentation] てんかんモデルラットの脳エネルギー代謝に及ぼすMK-801の影響2010
- Author(s)
  三船祐輔, 野口翔嗣, 桃崎壮太郎, 細井理恵, 井上修
- Organizer
  第130年会日本薬学会
- Place of Presentation
  岡山
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-19390319
[Presentation] 虚血耐性心筋における代謝とPBR結合に関する検討2009
- Author(s)
  沢田義一、宮武由梨子、桃崎壮太郎、細井理恵、井上修
- Organizer
  第9回放射性医薬品・画像診断薬研究会
- Place of Presentation
  京都
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-19390319
[Presentation] 虚血耐性心筋における代謝とPBR結合に関する検討2009
- Author(s)
  沢田義一, 宮武由梨子, 桃崎壮太郎, 細井理恵, 井上修
- Organizer
  第9回放射性医薬品・画像診断薬研究会
- Place of Presentation
  京都
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-19390319
[Presentation] 電気けいれん刺激がラット脳血流・糖代謝・グリア活性に与える影響について2009
- Author(s)
  安田和幸、小林薫、細井理恵、井上修、本橋伸高
- Organizer
  第31回日本生物学的精神医学会
- Place of Presentation
  京都、国立京都国際会館
- Year and Date
  2009-04-24
- Data Source
  KAKENHI-PROJECT-18591278
[Presentation] In vivoマイクロダイアリシスradio-LCを用いたラット線条体細胞外液中13N-アンモニアの動態計測2009
- Author(s)
  岡田真希, 中尾隆士, 細井理恵, 張明栄, 入江俊章, 福村利光, 鈴木和年, 井上修
- Organizer
  第49回日本核医学会総会
- Place of Presentation
  旭川
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-19390319
[Presentation] グリア細胞代謝阻害時における11C-Benzyl Acetateおよび13N-NH3ラット線条体マイクロダイアリシスin vivo動態計測2009
- Author(s)
  岡田真希, 中尾隆士, 細井理恵, 入江俊章, 福村利光, 鈴木和年, 井上修
- Organizer
  第129年会日本薬学会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19390319
[Presentation] グルタミン酸注入による神経障害時の脳循環・代謝に関する検討2009
- Author(s)
  桃崎壮太郎, 広瀬慎一郎, 佐々木和成, 細井理恵, 井上修
- Organizer
  第129年会日本薬学会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19390319
[Presentation] メチルエチルケトンによるケイレン発作抑制作用と糖代謝について2009
- Author(s)
  桃崎壮太郎, 山田明史, 澤田義一, 細井理恵, 井上修
- Organizer
  第49回日本核医学会総会
- Place of Presentation
  旭川
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-19390319
[Presentation] 興奮性アミノ酸によるラット脳の血流・代謝のDecouplingに関する検討2008
- Author(s)
  産田雄介, 沢田義一, 広瀬慎一郎, 桃崎壮太郎, 細井理恵, 井上修
- Organizer
  第128年会日本薬学会
- Place of Presentation
  横浜
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19390319
[Presentation] リチウムピロカルピンてんかんモデルにおけるメチルエチルケトンのケイレン抑制作用と血流画像2008
- Author(s)
  杉山恵理子, 松木祐依奈, 桃崎壮太郎, 細井理恵, 長谷部伸嘉, 阿部浩司, 井上修
- Organizer
  第8回放射性医薬品・画像診断薬研究会
- Place of Presentation
  京都
- Year and Date
  2008-12-06
- Data Source
  KAKENHI-PROJECT-19390319
[Presentation] アセトンによるてんかん発作抑制作用とグリア細胞への14C-酢酸の取り込みに関する検討2008
- Author(s)
  杉山恵理子, 細井理恵, 桃崎壮太郎, 井上修
- Organizer
  第128年会日本薬学会
- Place of Presentation
  横浜
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19390319
[Presentation] イボテン酸注入早期のラット脳における糖代謝の亢進と酸素代謝について2008
- Author(s)
  細井理恵, 桃崎壮太郎, 合瀬恭幸, 福田肇, 樋掛正明, 林拓也, 渡部浩司, 三宅義徳, 飯田秀博, 井上修
- Organizer
  第48回日本核医学会総会
- Place of Presentation
  千葉
- Year and Date
  2008-10-25
- Data Source
  KAKENHI-PROJECT-19390319
[Presentation] 薬物誘発性のけいれん発作時における14C-酢酸取込みについて2008
- Author(s)
  細井理恵, 望月智広, 桃崎壮太郎, 井上修
- Organizer
  第128年会日本薬学会
- Place of Presentation
  横浜
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19390319
[Presentation] メチルエチルケトンによるケイレン発作抑制作用と[14C]酢酸の取り込み2008
- Author(s)
  杉山恵理子, 細井理恵, 桃崎壮太郎, 井上修
- Organizer
  第48回日本核医学会総会
- Place of Presentation
  千葉
- Year and Date
  2008-10-25
- Data Source
  KAKENHI-PROJECT-19390319
[Presentation] グリア代謝抑制時におけるラット脳血流の亢進に関する検討2007
- Author(s)
  広瀬慎一郎, 細井理恵, 桃崎壮太郎, 畑澤順, 井上修
- Organizer
  第47回日本核医学会総会
- Place of Presentation
  仙台
- Year and Date
  2007-11-04
- Data Source
  KAKENHI-PROJECT-19390319
[Presentation] Li-pilocarpineてんかんモデルにおける14C-酢酸取込みの亢進について2007
- Author(s)
  細井理恵, 北野大介, 桃崎壮太郎, 井上修
- Organizer
  第47回日本核医学会総会
- Place of Presentation
  仙台
- Year and Date
  2007-11-04
- Data Source
  KAKENHI-PROJECT-19390319
[Presentation] 超高比放射能標識リガンドによる生体での微量現象の解明について2007
- Author(s)
  井上修
- Organizer
  第7回放射性医薬品・画像診断薬研究会
- Place of Presentation
  京都
- Year and Date
  2007-09-29
- Data Source
  KAKENHI-PROJECT-19659006
[Presentation] [14C]Benzyl Acetate の脳内動態の測定とその解析
- Author(s)
  香川智彦、吉野恵子、柳本和彦、細井理恵、木村敦臣、井上修、岡田真希、張明栄
- Organizer
  第１２回放射性医薬品・画像診断薬研究会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-23591767

1. HOSOI Rie (30291446)

# of Collaborated Projects: 6 results

# of Collaborated Products: 25 results
2. SUZUKI Kazutoshi (90162932)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
3. HATAZAWA Jun (70198745)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
4. KOBAYASHI Kaoru (90256933)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
5. ZHANG Ming-Rong (80443076)

# of Collaborated Projects: 4 results

# of Collaborated Products: 10 results
6. MURASE Kenya (50157773)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
7. WATANABE Yasuyoshi (40144399)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. YAMAGUCHI Masatoshi (50117280)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
9. OKU Naohiko (40346193)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
10. ONOE Hirotaka (80214196)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. KANOSUE Kazuyuki (50127213)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. NAGASHIMA Kei (40275194)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. YAMATODANI Atsushi (30116123)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 古澤佳也 (50260237)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. MOTOHASHI Nobutaka (30166342)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. TAMAOKI Toshio (60345709)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. UMEDA Takako (80345719)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. MOMOSAKI Sotaro (30379268)

# of Collaborated Projects: 1 results

# of Collaborated Products: 19 results
19. SHIMOSEGAWA Eku (30370258)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. ABE Kohji (80571207)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. YANAMOTO Kazuhiko (70531531)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
22. FUKUMURA Toshimitsu (90199266)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. OKADA Maki (00415407)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
24. MIWA Souichi (40157706)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. HARADAHIRA Terushi (50181029)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. BEPPU Shintaro (40113500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. FUJIWARA Hideaki (90107102)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. ISHIKURA Fuminobu (50303970)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. HASEGAWA Shinji (00314328)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. TAMURA Shinichi (30029540)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. NOHTA Hitoshi (20164668)

# of Collaborated Projects: 1 results

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32. YOSHIDA Hideyuki (20301690)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. TODOROKI Kenichiro (70341451)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
34. YOSHITAKE Takashi (90406249)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 今村一之 (30203326)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 安藤興一 (00159526)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 鈴木雅雄 (70281673)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
38. 高井伸彦 (70373389)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
39. 加賀美真人 (60293453)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. 細野剛良 (60294104)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. LANGSTROM Bengt

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. TAKEUCHI Yuko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. 渡邊恭良

# of Collaborated Projects: 1 results

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44. BENGT Langst

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

INOUE Osamu 井上 修

渡辺 恭良 ワタナベ ヤスヨシ

Research Projects

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Co-Researchers

Evaluation of 14C(11C)-Benzyl acetate as a potential probe for the measurement of glial metabolism.Principal Investigator

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Study on functional roles of PBR (TSPO) in glia and myocardiumPrincipal Investigator

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超高比放射能標識リガンドによる生体超微量現象の解明Principal Investigator

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Development of RI probe for the measurement of glial metabolism.Principal Investigator

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Development of receptor activation method for brain imaging with PET or SPECTPrincipal Investigator

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INOUE Osamu 井上修

渡辺恭良ワタナベヤスヨシ