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SAKAMOTO Toshihisa  阪本 敏久

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阪本 敏久

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Researcher Number 50178571
Affiliation (based on the past Project Information) *help 2015: 防衛医科大学校, その他部局等, 教授
2015: 防衛医科大学校病院, 救急部, 部長
2014 – 2015: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, その他部局等, 教授
2011 – 2014: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, 病院, 教授
2012: 防衛医科大学校, 病院, 教授
1986: 大阪大学, 医学部, 助手
Review Section/Research Field
Except Principal Investigator
Emergency medicine / General surgery / Integrated Nutrition Science / Bacteriology (including Mycology)
Keywords
Except Principal Investigator
クッパー細胞 / レスベラトロール / 活性酸素 / Pituitary gland / Kidney / Liver / Heart / Epinephrine / Arginine vasopressin / Brain death … More / 循環動態 / 骨髄機能 / 膵機能 / 腎機能 / 肝機能 / 心機能 / 抗利尿ホルモン(ADH) / 病理 / 脳下垂体 / 腎臓 / 肝臓 / 心臓 / エピネフリン / 抗利尿ホルモン / 脳死 / 脂肪滴 / ADFP / 脂肪肝 / 合成CRP / グルココルチコイド受容体 / 核内受容体 / ナノ医学 / 重症感染症 / エンドトキシントレランス / 光線力学療法 / 止血ナノ粒子 / ナノシート / ursodepxycolic acid / 外科侵襲 / compromised hosts / MKN45 / cell proliferation / Proteus mirabillis / 胃がん細胞 / 胃内起因菌 / Helicobacter pylori / 病原性 / NK細胞 / 細菌感染 / マウス熱傷モデル / 免疫不全 / CD11b陽性Kupffer細胞 / CD68陽性Kupffer細胞 / CD11b陽性クッパー細胞 / CD68陽性クッパー細胞 / IL-18 / 熱傷後感染 / 好中球 / 複合免疫不全 / 熱傷 Less
  • Research Projects

    (5 results)
  • Research Products

    (9 results)
  • Co-Researchers

    (28 People)
  •  Management against surgical stress in compromised hosts

    • Principal Investigator
      Kinoshita Manabu
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Emergency medicine
    • Research Institution
      National Defense Medical College
  •  Resveratrol ameliorates high-fat-diet-induced fatty liver by increasing CD68 positive Kupffer cells.

    • Principal Investigator
      Nishikawa Kahoko
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Integrated Nutrition Science
    • Research Institution
      Chuo University
      National Defense Medical College
  •  Bacterial pathogen Helicobacter pylori may augment gene expressions of TLR4 and TLR5 on cancer cells under coexistence with another gastric bacteria Proteus mirabilis

    • Principal Investigator
      NISHIKAWA Kahoko
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      防衛医科大学校
      National Defense Medical College
  •  Mechanical analyses and treatment of immunodeficiency following burn injury

    • Principal Investigator
      KINOSHITA Manabu
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Emergency medicine
    • Research Institution
      National Defense Medical College
  •  Changes of heart, liver, kidney and endocrine glands in brain death.

    • Principal Investigator
      SUGIMOTO Tsuyoshi
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Department of Traumatology, Osaka University Hospital

All 2015 2014 2013 2012 Other

All Journal Article Presentation

  • [Journal Article] Resveratrol increases CD68+ Kupffer cells colocalized with adipose differentiation-related protein and ameliorates high-fat-diet-induced fatty liver in mice.2015

    • Author(s)
      Nishikawa K, Iwaya K, Kinoshita M, Fujiwara Y, Akao M, Sonoda M, Thiruppathi S, Suzuki T, Hiroi S, Seki S, Sakamoto T.
    • Journal Title

      Mol Nutr Food Res

      Volume: 12 Issue: 6 Pages: 564-564

    • DOI

      10.1002/mnfr.201400564

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24590457, KAKENHI-PROJECT-25504021, KAKENHI-PROJECT-25460508, KAKENHI-PROJECT-25293369
  • [Journal Article] Noradrenalin effectively rescues mice from blast lung injury caused by laser-induced shock waves.2015

    • Author(s)
      Miyawaki H, Saito D, Hagisawa K, Noguchi M, Sato S, Kinoshita M, Miyazaki H, Sato Y, Harada N, Sakamoto T.
    • Journal Title

      Intensive Care Medicine Experimental

      Volume: 32 Issue: 1 Pages: 32-32

    • DOI

      10.1186/s40635-015-0069-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25462843, KAKENHI-PROJECT-25293369
  • [Journal Article] Detection of changes in the structure and distribution map of triacylglycerol in fatty liver model by MALDI-Spiral TOF2014

    • Author(s)
      Nishikawa K, Hashimoto M, Itoh Y, Hiroi S, Kusai A, Hirata F, Sakamoto T, Iwaya K
    • Journal Title

      FEBS Open Bop

      Volume: 19 Issue: 1 Pages: 179-84

    • DOI

      10.1016/j.fob.2014.02.005

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24590457, KAKENHI-PROJECT-25504021
  • [Journal Article] 人工血小板H12(ADP)リポソームを用いた急性血小板減少病態への止血・救命対策.2013

    • Author(s)
      西川可穂子、萩沢康介、柳川錬平、土井麻実、鈴木英紀、齋藤大蔵、阪本敏久、武岡真司、半田誠、木下 学
    • Journal Title

      人工血液

      Volume: 21 Pages: 60-67

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293369
  • [Journal Article] Fibrinogen γ-chain peptide-coated, adenosine diphosphate-encapsulated liposomes rescue thrombocytopenic rabbits from non-compressible liver hemorrhage2012

    • Author(s)
      Nishikawa K, Hagisawa K, Kinoshita M, Shono S, Katsuno S, Doi M, Yanagawa R, Suzuki H, Iwaya K, Saitoh D, Sakamoto T, Seki S, Takeoka S, Handa M
    • Journal Title

      J Thromb Haemost

      Volume: 10 Pages: 2137-2148

    • Data Source
      KAKENHI-PROJECT-22592027
  • [Presentation] Resveratrol increases cd68+kupffer cells co-localized with adipose differentiation-related protein (adfp) and ameliorates high-fat-diet-induced fatty liver in mice.2015

    • Author(s)
      K Nishikawa, K .Iwaya, M Knoshita, Y Fujiwara, S Thiuppathi, T Suzuki, S Seki, T Sakamoto
    • Organizer
      4th European Congress of Immunology 2015
    • Place of Presentation
      ウィーン (オーストリア )
    • Year and Date
      2015-09-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25504021
  • [Presentation] Resveratrol increases CD68 positive Kupffer cells with phagocytic activity to lipid droplets and ameliorates high-fat diet induced fatty liver in mice2013

    • Author(s)
      Nishikawa K, Kinoshita M, Iwaya K, Sakamoto T, Seki S.
    • Organizer
      第42回日本免疫学会総会
    • Place of Presentation
      幕張(千葉)
    • Data Source
      KAKENHI-PROJECT-25504021
  • [Presentation] 食餌性レスベラトロールが肝臓に蓄積する中性脂肪へ与える影響2013

    • Author(s)
      西川可穂子、橋本将弘、久保歩、阪本敏久、岩屋啓一
    • Organizer
      第67回日本栄養・食糧学会大会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-25504021
  • [Presentation] Resveratrol ameliorates fatty liver by reducing the size of lipid droplet without changing liver fat species.

    • Author(s)
      K. Nishikawa, M. Hashimoto, Y. Itoh, S. Hiroi, T.Sakamoto, K. Iwaya
    • Organizer
      FEBS EMBO 2014 Conference
    • Place of Presentation
      Palais des Congrès, Paris, France
    • Year and Date
      2014-08-30 – 2014-09-04
    • Data Source
      KAKENHI-PROJECT-25504021
  • 1.  KINOSHITA Manabu (70531391)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 4 results
  • 2.  ONO Satoshi (30531355)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 1 results
  • 3.  NISHIKAWA Kahoko (20345416)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 6 results
  • 4.  SEKI Shuhji (80531392)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 3 results
  • 5.  SAITOH Daizoh (90531632)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 3 results
  • 6.  MIYAZAKI Hiromi (30531636)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  SHINOMIYA Nariyoshi (40505260)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  Tanaka Yuji (50221396)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  Morimoto Yuji (10449069)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  Takahashi Tetsuya (00589905)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  Nakashima Hiroyuki (10574064)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  Hagisawa Kosuke (50539244)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 13.  Hinoki Akinari (90383257)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  Takeoka Shinji (20222094)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  Handa Makoto (40129614)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 16.  Iwaya Keiichi (50312012)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 17.  Fujiwara Yoko (50293105)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 18.  SUGIMOTO Tsuyoshi (10028342)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  KINOSHITA Yoshihiro (30195341)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  UENISHI Masaaki (90176610)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  SUGIMOTO Hisashi (90127241)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  YOSHIOKA Toshiharu (60127313)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  横田 順一朗 (10166879)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  渋谷 正徳 (90187419)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  ISHIKAWA Takashi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 26.  小田 美規
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  土田 英俊
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 28.  佐藤 俊一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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