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NAWA HIROYUKI  那波 宏之

… Alternative Names

NAWA Hiroyuki  那波 宏之

那波 宏之  ナワ ヒロユキ

Less
Researcher Number 50183083
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-9177-1278
External Links
Affiliation (Current) 2025: 和歌山県立医科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help 2021 – 2024: 和歌山県立医科大学, 薬学部, 教授
1999 – 2020: Brain Research Institute, Niigata University Professor, 脳研究所, 教授
2003: 新潟大学, 脳研究科, 教授
1998: 新潟大, 脳研究所, 教授
1995 – 1997: 新潟大学, 脳研究所, 教授 … More
1994: Kyoto University Faculty of Medicine Associate Professor, 医学部, 助教授
1991: 京都大学, 医学部, 助教授
1990: 京都大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / Pathological medical chemistry / Basic Section 46020:Anatomy and histopathology of nervous system-related / Medium-sized Section 46:Neuroscience and related fields / Medium-sized Section 51:Brain sciences and related fields / General pharmacology / Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology / Neurophysiology / General neuroscience / Biological Sciences … More / Neuroscience in general / Psychiatric science / Pathological medical chemistry / Neuroscience in general … More
Except Principal Investigator
Biological Sciences / Basic Section 52030:Psychiatry-related / Applied health science / General pharmacology / Cerebral neurosurgery / Fusional basic brain science / Neurophysiology and muscle physiology / Ophthalmology / Biological Sciences Less
Keywords
Principal Investigator
統合失調症 / サイトカイン / 精神疾患 / ドパミン / BDNF / モデル動物 / 上皮成長因子 / 脳発達 / 神経発達 / シナプス … More / セロトニン / 神経栄養因子 / 大脳皮質 / 可塑性 / ニューロトロフィン / 一次聴覚野 / 脳波 / 幻聴 / ニューレグリン / 分子診断 / DNAチップ / ストレス / DNAアレイ / 神経栄養性因子 / 細胞外記録 / 事象関連電位 / 聴覚皮質 / 薬理遺伝学 / schizophrenia / 精神分裂病 / Neurotransmitter / ユニット記録 / 中脳ドパミン神経 / 死後脳 / 聴覚機能 / EGF / 脳 / 遺伝子プロファイル / マイクロアレイ / 認知行動 / 遺伝子プロファイリング / RNA / 遺伝子発現 / ジンクフィンガー / 線条体 / スパイン / 海馬 / PCR / NMDA / 老化 / Eph/Ephrin / 軸索伸長 / 回路改変 / コネクトーム / 軸索ガイダンス分子 / 神経回路 / 炎症 / カルシウムイメージング / 覚醒剤 / 錯聴 / 抗がん剤 / ファイバーフォトメトリー / 幻覚 / 統合失調症モデル / オシレーション / 感覚連合 / γオシレーション / トップダウン / ガンマオシレーション / 行動 / DREADD / 中脳 / SSRI / 社会性 / モノアミン / 社会ストレス / SSRI / ノルアドレナリン / プロテアソーム / フタルイミド化合物 / 神経発火 / セロトニン神経 / ユビキチン / セレブロン / レナリドミド / サリドマイド / stress / RNA profiling / interleukin-1 / cytokine / Mental disease / 診断 / 病態 / 血清 / HB EGF / TGF / インターロイキン-1 / neurotrophic / postmortem brain / sytokine / phencyclidine / neurotrophin / PCP / Receptor / Synapse / Knockout Mouse / Gene Targetting / Neurotropic / Growth Factor / ラジオイムノアッセイ / 神経成長因子 / 受容体 / ノックアウトマウス / 遺伝子破壊 / 成長因子 / 次世代シークエンサー / RNA‐SEQ / ユニット解析 / 自発発火 / 神経活動 / iPS細胞 / カリウムチャンネル / 黒質 / GDNF / RNA-SEQ / 自律発火 / 依存薬物 / 認知行動異常 / 非定型抗精神病薬 / OFF反応 / 脳内炎症 / 動物モデル / 発声 / GDNF / EGF / 脳疾患 / シナプス可塑性 / 基底核 / GABA / マイクロサテライト / CNV / コピー数 / 体細胞変異 / ゲノム不安定性 / IL-1 / プロスタグランジン / プレパルスインヒビション / 自閉症 / 遺伝子 / 脳神経 / トランスクリプトーム / 脳進化 / ゲノム配列 / DNAマイクロアレイ / 進化 / 霊長類 / 単核球 / 総合失調症 / 脳栄養因子 / 栄養因子 / 分子病態 / 脳病態 / プロファイリング / 差分PCR / 転写因子 / NT-3 / 神経分化 / ニューロペプチドY / 細胞培養 / シナプス形態 / クローニング / NMDA受容体 / アルツハイマー病 / 酵素免疫抗体法 / 神経変性 / 発達 / ペプチド / 酵素免疫学的測定 / 神経分化因子 / アセチルコリン / ソマトスタチン / サブスタンスP / VIP / 白血病阻止因子 / 交感神経 … More
Except Principal Investigator
統合失調症 / 精神疾患 / BDNF / Fyn / c-Fos / NMDA受容体 / E/Iバランス / バイオマーカー / トランスレーショナルリサーチ / E/Iバランス障害 / ガンマオシレーション / in silicoモデル / 神経回路 / 多階層オミクス / ストレス / シミュレーション / トランスオミクス / モデリング / マイクロ精神病態 / 種間横断比較 / 構成的理解 / マルチスケール / うつ病 / マイクロエンドフェアタイプ / 神経科学科学 / 躁うつ病 / 双極性障害 / 気分障害 / PTSD / マイクロエンドフェノタイプ / 精神病態 / 脳・神経 / 神経科学 / 生活習慣病 / マイオカイン / 運動療法 / 脳由来神経栄養因子 / 肥満 / 糖尿病 / Hippocampus / B-Amy|oid / NMDA receptors / Synaptic plasticity / Learning and memory / 放射状迷路学習 / アンチセンス / β-アミロイド蛋白 / 一酸化窒素 / 空間記憶 / 海馬 / β-アミロイド / シナプス可塑性 / 学習記憶 / Neurosurgery for epilepsy / Cortical dysplasia / Brain developmental error / DNA array / Gene analysis / Molecular pathology / Neuropathology / Intractable epilepsy / tubelin / hamartin / 結節性硬化症 / DNA macroarray / 剖検例 / Migration disorder / Bilateral periventricular nodular heterotopia / てんかん外科 / 皮質形成異常 / 脳発達障害 / DNAアレイ / 遺伝子解析 / 分子病理 / 神経病理 / 難治てんかん / neural information processing / memory / neuronal cell death / gene targeting / molecular diversity / cloning / metabotropic glutamate receptor / NMDA receptor / G蛋白共役受容体 / 遺伝子ファミリ- / 発現部位 / メタボトロピック受容体 / 特異的アゴニスト / 発現分布 / 細胞内情報伝達系 / イオン・チャンネル / 神経伝達制御 / 受容体サブタイプ / 二次ニューロン / 嗅覚記憶誘導 / 嗅覚系神経伝達 / 免疫組織化学 / 視覚系神経伝達 / メダボトロピック.グルタミン酸受容体 / グルタミン酸受容体 / 神経情報処理機構 / 記憶 / 神経細胞死 / 標的遺伝子破壊 / 分子多様性 / 遺伝子工学 / メタボトロピック・グルタミン酸受容体 / 胎児 / 行動 / サル / 新生児 / サイトカイン / 認知機能障害 / EGF / アカゲザル / コモンマーモセット / 生理特性 / 動物モデル / スパイク発火特性 / 上皮成長因子 / ニューレグリン / 神経栄養因子 / ドパミン / scanning lasar opthalmoscope(SLO) / 網膜神経節細胞 / SLO (scanning laser opthalmoscopy) / transgenic mouse / EGFP / thy1.2 / retinal ganglion cell death / 驚愕反応 / PPI / Src / マーカー遺伝子 / 病態 / 認知 / 脳発達 / シナプス / 行動解析 / ノックアウトマウス / 精神分裂病 Less
  • Research Projects

    (42 results)
  • Research Products

    (176 results)
  • Co-Researchers

    (74 People)
  •  炎症シグナルによる皮質神経回路形成の攪乱とリモデリングPrincipal Investigator

    • Principal Investigator
      那波 宏之
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 46020:Anatomy and histopathology of nervous system-related
    • Research Institution
      Wakayama Medical University
  •  全脳神経活動可視化と光遺伝学による幻覚の脳神経メカニズムの探求Principal Investigator

    • Principal Investigator
      那波 宏之
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Pioneering)
    • Review Section
      Medium-sized Section 46:Neuroscience and related fields
    • Research Institution
      Wakayama Medical University
  •  Translational research using neural oscillation in schizophrenia: Toward elucidating pathogenesis and developing novel therapeutic approaches

    • Principal Investigator
      平野 羊嗣
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52030:Psychiatry-related
    • Research Institution
      University of Miyazaki
  •  Constructive understanding of multi-scale dynamism of neuropsychiatric disorders

    • Principal Investigator
      Hayashi-Takagi Akiko
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Institute of Physical and Chemical Research
      Gunma University
  •  Constructive understanding of multi-layer processes underlying stress-induced cognitive and emotional changes and their implications for mental illnesses

    • Principal Investigator
      Furuyashiki Tomoyuki
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kobe University
  •  ドパミンによる皮質ガンマオシレーション調節と統合的感覚情報処理Principal Investigator

    • Principal Investigator
      那波 宏之
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Research Institution
      Niigata University
  •  Animal Modeling of Hallucination and Its Neurobiological AnalysisPrincipal Investigator

    • Principal Investigator
      Nawa Hiroyuki
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 51:Brain sciences and related fields
    • Research Institution
      Niigata University
  •  Mutual interactions of monoaminergic neurons in stress resilience and sensitivityPrincipal Investigator

    • Principal Investigator
      Nawa Hiroyuki
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Niigata University
  •  Pharmacological actions of R-thalidomide on serotonin neuronsPrincipal Investigator

    • Principal Investigator
      Nawa Hiroyuki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Niigata University
  •  The prevention and treatment of obesity and diabetes with BDNF, a myokine derived from skeletal muscle

    • Principal Investigator
      HANYU Osamu
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied health science
    • Research Institution
      Niigata University
  •  External and Internal Factors Regulating Inputs/Output Development of Midbrain Dopaminergic NeuronsPrincipal Investigator

    • Principal Investigator
      Nawa Hiroyuki
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurophysiology / General neuroscience
    • Research Institution
      Niigata University
  •  Cytokine-Induced Neuropathologic Endophenotypes of Psychiatric DiseasesPrincipal Investigator

    • Principal Investigator
      Nawa Hiroyuki
    • Project Period (FY)
      2012 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Niigata University
  •  Study on abnormal behavior induced by cytokine administration in nonhuman primates.-An attempt to produce a monkey model of schizophrenia-

    • Principal Investigator
      NAKAMURA Katsuki
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Fusional basic brain science
    • Research Institution
      Kyoto University
  •  Unraveling the micro-endophenotypes of psychiatric disorders at the molecular, cellular and circuit levels

    • Principal Investigator
      Kida Satoshi
    • Project Period (FY)
      2012 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo University of Agriculture
  •  Pathophysiological alterations of intrinsic properties and neural activity in the midbrain dopaminergic neurons mediated by neurotrophic factors

    • Principal Investigator
      NAMBA Hisaaki
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurophysiology and muscle physiology
    • Research Institution
      Niigata University
  •  Functional and Phenotypic Regulation of GABAergic Development with Neurotrophic FactorsPrincipal Investigator

    • Principal Investigator
      NAWA Hiroyuki
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neuroscience in general
    • Research Institution
      Niigata University
  •  統合失調症における体細胞変異と染色体脆弱性の脳ゲノム研究Principal Investigator

    • Principal Investigator
      那波 宏之
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Psychiatric science
    • Research Institution
      Niigata University
  •  Abnormal brain cytokine signaling in neurobehavioral impairmentsPrincipal Investigator

    • Principal Investigator
      NAWA Hiroyuki
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Niigata University
  •  Comparative Transcriptome Study of BrainPrincipal Investigator

    • Principal Investigator
      NAWA Hiroyuki
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Niigata University
  •  精神疾患の遺伝子発現データベースの構築と分子病態解析Principal Investigator

    • Principal Investigator
      那波 宏之
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Niigata University
  •  精神疾患の遺伝子発現データベースの構築と分子病態解析Principal Investigator

    • Principal Investigator
      那波 宏之
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Niigata University
  •  精神疾患の遺伝子発現データベースの構築と分子病態解析Principal Investigator

    • Principal Investigator
      那波 宏之
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Niigata University
  •  網膜神経節細胞蛍光発色マウスの作製と網膜神経節細胞死の新たな評価系の確立

    • Principal Investigator
      福地 健郎
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Ophthalmology
    • Research Institution
      Niigata University
  •  精神疾患の脳内遺伝子発現データベースの構築と分子病態解析Principal Investigator

    • Principal Investigator
      那波 宏之
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Niigata University
  •  脳内サイトカインによる中枢神経機能の制御メカニズム:分子から精神活動へPrincipal Investigator

    • Principal Investigator
      那波 宏之
    • Project Period (FY)
      2001 – 2005
    • Research Category
      Grant-in-Aid for Creative Scientific Research
    • Research Institution
      Niigata University
  •  DNAアレイと最新PCR法を用いた精神疾患の分子病態解析とデータベース構築Principal Investigator

    • Principal Investigator
      那波 宏之
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Niigata University
  •  Schizophrenic Abnormality in Molecular Signaling and RNA Expression ProfilingPrincipal Investigator

    • Principal Investigator
      NAWA Hiroyuki
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      NIIGATA UNIVERSITY
  •  A study on the molecular pathomechanisms underflying intractable epilepsy

    • Principal Investigator
      TAKAHASHI Hitoshi
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      NIIGATA UNIVERSITY
  •  Role of brain-derived neurotrophic factor (BDNF) in learning and memory

    • Principal Investigator
      YAMADA Kiyofumi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Nagoya University
  •  精神分裂病とそのモデルとしてのノックアウトマウスの総合的比較・分析

    • Principal Investigator
      SOMEYA Toshiyuki
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      Niigata University
  •  Brain Expression of Neurotrophins and Its Relation to SchizophreniaPrincipal Investigator

    • Principal Investigator
      NAWA Hiroyuki
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Niigata University
  •  NMDA受容体刺激で誘導されるシナプスに局在する高分子の検索Principal Investigator

    • Principal Investigator
      那波 宏之
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Niigata University
  •  神経伝導物質とその受容体の発現維持に必要とされる神経栄養性因子の役割Principal Investigator

    • Principal Investigator
      那波 宏之
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Niigata University
  •  NMDA受容体刺激で誘導されるシナプスに局在する高分子の検索Principal Investigator

    • Principal Investigator
      那波 宏之
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Niigata University
  •  シナプス形成とその発達における神経分化因子の機能と役割Principal Investigator

    • Principal Investigator
      那波 宏之
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Niigata University
  •  ニューロトロフィンによるペプチド作動性脳神経細胞の分化誘導Principal Investigator

    • Principal Investigator
      那波 宏之
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neuroscience in general
    • Research Institution
      Niigata University
  •  Intercelluar Bioactive Molecules in Neural CircuitPrincipal Investigator

    • Principal Investigator
      NAWA Hiroyuki
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      NIIGATA UNIVERSITY
  •  神経伝達物質の発現維持に必要とされる神経栄養性因子の役割Principal Investigator

    • Principal Investigator
      那波 宏之
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Niigata University
  •  NMDA受容体刺激で誘導されるシナプスに局在する高分子の検索Principal Investigator

    • Principal Investigator
      那波 宏之
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Niigata University
  •  シナプス形成とその発達における神経分化因子の機能と役割Principal Investigator

    • Principal Investigator
      那波 宏之
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Niigata University
  •  Functions and regulation of glutamate receptors and their roles in central neuronal functions.

    • Principal Investigator
      NAKANISHI Shigetada
    • Project Period (FY)
      1991 – 1994
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Research Institution
      KYOTO UNIVERSITY
  •  神経伝達物質,並びにそのレセプタ-の発現に対する分化誘導因子の同定Principal Investigator

    • Principal Investigator
      那波 宏之
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University

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  • [Book] 第3章「脳回路と認知の仕組みから見た精神疾患」ブルーバックス「心の病」の脳科学 なぜ生じるのか、どうすれば治るのか(林(高木) 朗子、加藤 忠史編)2023

    • Author(s)
      那波宏之
    • Total Pages
      288
    • Publisher
      講談社
    • ISBN
      9784065283639
    • Data Source
      KAKENHI-PLANNED-18H05429
  • [Book] 統合失調症2013

    • Author(s)
      那波宏之(分筆)
    • Total Pages
      768
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PLANNED-24116010
  • [Book] Methods in Molecular Biology Volume 8292012

    • Author(s)
      Nawa H, Yamada K
    • Publisher
      Hum ana Press, Clifton, New Jersey
    • Data Source
      KAKENHI-PROJECT-22300107
  • [Journal Article] Schizophrenia Animal Modeling with Epidermal Growth Factor and Its Homologs: Their Connections to the Inflammatory Pathway and the Dopamine System2023

    • Author(s)
      Sotoyama Hidekazu、Namba Hisaaki、Tohmi Manavu、Nawa Hiroyuki
    • Journal Title

      Biomolecules

      Volume: 13 Issue: 2 Pages: 372-372

    • DOI

      10.3390/biom13020372

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-18H05429
  • [Journal Article] 統合失調症の動物モデルを使った新規診断治療法の開発2023

    • Author(s)
      那波宏之、難波寿明
    • Journal Title

      臨床精神医学

      Volume: 52 Pages: 561-570

    • Data Source
      KAKENHI-PLANNED-18H05429
  • [Journal Article] Increased self-triggered vocalizations in an epidermal growth factor-induced rat model for schizophrenia2022

    • Author(s)
      Narihara I, Yokoyama H, Namba H, Sotoyama H, Inaba H, Kitayama E, Tamada K, Takumi T, Nawa H
    • Journal Title

      Sci Rep

      Volume: 12 Issue: 1 Pages: 129017-129017

    • DOI

      10.1038/s41598-022-17174-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H04813, KAKENHI-PLANNED-18H05429
  • [Journal Article] The dual role of dopamine in the modulation of information processing in the prefrontal cortex underlying social behavior2022

    • Author(s)
      Sotoyama Hidekazu、Inaba Hiroyoshi、Iwakura Yuriko、Namba Hisaaki、Takei Nobuyuki、Sasaoka Toshikuni、Nawa Hiroyuki
    • Journal Title

      The FASEB Journal

      Volume: 36 Issue: 2

    • DOI

      10.1096/fj.202101637r

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-18H05429, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-17H04030, KAKENHI-PROJECT-22H04922
  • [Journal Article] Rat call-evoked electrocorticographic responses and intercortical phase synchrony impaired in a cytokine-induced animal model for schizophrenia2022

    • Author(s)
      Narihara Itaru、Kitajo Keiichi、Namba Hisaaki、Sotoyama Hidekazu、Inaba Hiroyoshi、Watanabe Dai、Nawa Hiroyuki
    • Journal Title

      Neuroscience Research

      Volume: 175 Pages: 62-72

    • DOI

      10.1016/j.neures.2021.10.007

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-18H05428, KAKENHI-PLANNED-18H05429
  • [Journal Article] EGF Downregulates Presynaptic Maturation and Suppresses Synapse Formation In Vitro and In Vivo2022

    • Author(s)
      Takei Nobuyuki、Yokomaku Daisaku、Yamada Takaho、Nagano Tadasato、Kakita Akiyoshi、Namba Hisaaki、Ushiki Tatsuo、Takahashi Hitoshi、Nawa Hiroyuki
    • Journal Title

      Neurochemical Research

      Volume: Epub ahead Issue: 9 Pages: 2632-2644

    • DOI

      10.1007/s11064-021-03524-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-18H05429
  • [Journal Article] Elevation of EGR1/zif268, a Neural Activity Marker, in the Auditory Cortex of Patients with Schizophrenia and its Animal Model2022

    • Author(s)
      Iwakura Yuriko、Kawahara-Miki Ryoka、Kida Satoshi、Sotoyama Hidekazu、Gabdulkhaev Ramil、Takahashi Hitoshi、Kunii Yasuto、Hino Mizuki、Nagaoka Atsuko、Izumi Ryuta、Shishido Risa、Someya Toshiyuki、Yabe Hirooki、Kakita Akiyoshi、Nawa Hiroyuki
    • Journal Title

      Neurochemical Research

      Volume: in press Issue: 9 Pages: 2715-2727

    • DOI

      10.1007/s11064-022-03599-9

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H03944, KAKENHI-PROJECT-20K21265, KAKENHI-PROJECT-22K19142, KAKENHI-PROJECT-21K15715, KAKENHI-PROJECT-22H00358, KAKENHI-PROJECT-20H03597, KAKENHI-PLANNED-18H05429, KAKENHI-PUBLICLY-21H00180, KAKENHI-PUBLICLY-22H05486, KAKENHI-PROJECT-22H00469
  • [Journal Article] Inter‐breeder differences in prepulse inhibition deficits of C57BL/6J mice in a maternal immune activation model2021

    • Author(s)
      Kobayashi Yutaro、Inaba Hiroyoshi、Iwakura Yuriko、Namba Hisaaki、Sotoyama Hidekazu、Murata Yui、Iwamoto Kazuya、Nawa Hiroyuki
    • Journal Title

      Neuropsychopharmacology Reports

      Volume: 41 Issue: 3 Pages: 416-421

    • DOI

      10.1002/npr2.12178

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-18H05429, KAKENHI-PLANNED-18H05430, KAKENHI-PROJECT-18H02753
  • [Journal Article] 統合失調症モデル動物研究とその展望―幻聴の再現可能性―2021

    • Author(s)
      那波宏之
    • Journal Title

      精神神経学雑誌

      Volume: 123 Pages: 761-768

    • Data Source
      KAKENHI-PLANNED-18H05429
  • [Journal Article] The dopamine D2 agonist quinpirole impairs frontal mismatch responses to sound frequency deviations in freely moving rats2021

    • Author(s)
      Inaba Hiroyoshi、Namba Hisaaki、Kida Satoshi、Nawa Hiroyuki
    • Journal Title

      Neuropsychopharmacology Reports

      Volume: - Issue: 3 Pages: 405-415

    • DOI

      10.1002/npr2.12199

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K17084, KAKENHI-PLANNED-18H05429, KAKENHI-PLANNED-18H05434, KAKENHI-PROJECT-18H03944, KAKENHI-PROJECT-20K21265, KAKENHI-PROJECT-19H01047
  • [Journal Article] 増大特集 脳とからだ Ⅳ.内分泌系と脳の相互作用 慢性ストレス負荷と抗うつ剤による脳内モノアミン神経活動のバランス制御2021

    • Author(s)
      那波宏之、鬼川真紀、難波寿明、外山英和
    • Journal Title

      生体の科学

      Volume: 72 Issue: 5 Pages: 497-500

    • DOI

      10.11477/mf.2425201425

    • ISSN
      0370-9531, 1883-5503
    • Year and Date
      2021-10-15
    • Data Source
      KAKENHI-PROJECT-17H04030
  • [Journal Article] Resting-state dopaminergic cell firing in the ventral tegmental area negatively regulates affiliative social interactions in a developmental animal model of schizophrenia2021

    • Author(s)
      Sotoyama Hidekazu、Namba Hisaaki、Kobayashi Yutaro、Hasegawa Taku、Watanabe Dai、Nakatsukasa Ena、Sakimura Kenji、Furuyashiki Tomoyuki、Nawa Hiroyuki
    • Journal Title

      Translational Psychiatry

      Volume: 11 Issue: 1 Pages: 236-236

    • DOI

      10.1038/s41398-021-01346-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-18H05428, KAKENHI-PLANNED-18H05429, KAKENHI-PROJECT-18K06868, KAKENHI-PROJECT-21H04812
  • [Journal Article] Perinatal Epidermal Growth Factor Signal Perturbation Results in the Series of Abnormal Auditory Oscillations and Responses Relevant to Schizophrenia2021

    • Author(s)
      Inaba Hiroyoshi、Kai Ryota、Namba Hisaaki、Sotoyama Hidekazu、Jodo Eiichi、Nin Fumiaki、Hibino Hiroshi、Yabe Hirooki、Eifuku Satoshi、Horii Arata、Nawa Hiroyuki
    • Journal Title

      Schizophrenia Bulletin Open

      Volume: 2 Issue: 1 Pages: 1-12

    • DOI

      10.1093/schizbullopen/sgaa070

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K17084, KAKENHI-PLANNED-18H05429, KAKENHI-PROJECT-18K19495, KAKENHI-PROJECT-18H04062
  • [Journal Article] 統合失調症モデル動物研究とその展望;幻聴の再現可能性2021

    • Author(s)
      那波宏之
    • Journal Title

      精神神経学雑誌

      Volume: 印刷中

    • Data Source
      KAKENHI-PROJECT-18K19495
  • [Journal Article] Post-pubertal difference in nigral dopaminergic cells firing in the schizophrenia model prepared by perinatal challenges of a cytokine, EGF2020

    • Author(s)
      Namba H, Nawa H
    • Journal Title

      Neuroscience

      Volume: 未定

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04030
  • [Journal Article] S25-1 Mismatch negativity and frequency spectra of electrocorticogram to duration deviance in a rat model of schizophrenia2020

    • Author(s)
      Inaba Hiroyoshi、Namba Hisaaki、Sotoyama Hidekazu、Narihara Itaru、Jodo Eiichi、Yabe Hirooki、Eifuku Satoshi、Nawa Hiroyuki
    • Journal Title

      Clinical Neurophysiology

      Volume: 131 Issue: 10 Pages: e257-e257

    • DOI

      10.1016/j.clinph.2020.04.115

    • Open Access
    • Data Source
      KAKENHI-PROJECT-19K17084, KAKENHI-PLANNED-18H05429, KAKENHI-PROJECT-18K19495
  • [Journal Article] Inter-breeder differences in prepulse inhibition deficits of C57BL/6J mice in a maternal infection model for schizophrenia2020

    • Author(s)
      Kobayashi Yutaro、Inaba Hiroyoshi、Iwakura Yuriko、Namba Hisaaki、Sotoyama Hidekazu、Murata Yui、Iwamoto Kazuya、Nawa Hiroyuki
    • Journal Title

      BioRxiv

      Volume: N/A

    • DOI

      10.1101/2020.12.24.423890

    • Open Access
    • Data Source
      KAKENHI-PLANNED-18H05429
  • [Journal Article] EL-1 Animal modeling of schizophrenia and its evaluation; use of auditory ERPs2020

    • Author(s)
      Nawa Hiroyuki、Narihara Itaru、Sotoyama Hidekazu、Namba Hisaaki、Inaba Hiroyoshi
    • Journal Title

      Clinical Neurophysiology

      Volume: 131 Issue: 10 Pages: e237-e237

    • DOI

      10.1016/j.clinph.2020.04.030

    • Open Access
    • Data Source
      KAKENHI-PROJECT-19K17084, KAKENHI-PLANNED-18H05429
  • [Journal Article] Post-pubertal Difference in Nigral Dopaminergic Cells Firing in the Schizophrenia Model Prepared by Perinatal Challenges of a Cytokine, EGF2020

    • Author(s)
      Namba H, Nawa H
    • Journal Title

      Neuroscience

      Volume: - Pages: 22-32

    • DOI

      10.1016/j.neuroscience.2020.06.003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06868, KAKENHI-PLANNED-18H05429
  • [Journal Article] Clozapine-dependent inhibition of EGF/neuregulin receptor (ErbB) kinases2019

    • Author(s)
      Kobayashi Yutaro、Iwakura Yuriko、Sotoyama Hidekazu、Kitayama Eiko、Takei Nobuyuki、Someya Toshiyuki、Nawa Hiroyuki
    • Journal Title

      Translational Psychiatry

      Volume: 9 Issue: 1 Pages: 181-181

    • DOI

      10.1038/s41398-019-0519-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-18H05429, KAKENHI-PROJECT-16K07053
  • [Journal Article] Sound frequency dependence of duration mismatch negativity recorded from awake rats2019

    • Author(s)
      Inaba Hiroyoshi、Namba Hisaaki、Sotoyama Hidekazu、Narihara Itaru、Jodo Eiichi、Yabe Hirooki、Eifuku Satoshi、Nawa Hiroyuki
    • Journal Title

      Neuropsychopharmacology Reports

      Volume: 40 Issue: 1 Pages: 96-101

    • DOI

      10.1002/npr2.12090

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K17084, KAKENHI-PLANNED-18H05429, KAKENHI-PROJECT-16K10219, KAKENHI-PUBLICLY-18H04938
  • [Journal Article] Neonatal exposure to an inflammatory cytokine, epidermal growth factor, results in the deficits of mismatch negativity in rats2019

    • Author(s)
      Jodo Eiichi、Inaba Hiroyoshi、Narihara Itaru、Sotoyama Hidekazu、Kitayama Eiko、Yabe Hirooki、Namba Hisaaki、Eifuku Satoshi、Nawa Hiroyuki
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 7503-7503

    • DOI

      10.1038/s41598-019-43923-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K17084, KAKENHI-PLANNED-18H05429, KAKENHI-PROJECT-16K10219
  • [Journal Article] Neonatal exposure to an inflammatory cytokine, epidermal growth factor, results in the deficits of mismatch negativity in rats2019

    • Author(s)
      E Jodo, H Inaba, I Narihara, H Sotoyama, E Kitayama, H Yabe, H Namba, S Eifuku, H Nawa
    • Journal Title

      Scientific Report

      Volume: 未定

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-18H04938
  • [Journal Article] Pathological alterations of chondroitin sulfate moiety in postmortem hippocampus of patients with schizophrenia2018

    • Author(s)
      Yukawa、Iwakura、Takei、Saito、Watanabe、Toyooka、Igarashi、Niizato、Oshima、Kunii、Yabe、Matsumoto、Wada、Hino、Iritanii、Niwa、Takeuchi、Takahashi、Kakita、Someya、Nawa
    • Journal Title

      Psychiatry Research

      Volume: 270 Pages: 940-946

    • DOI

      10.1016/j.psychres.2018.10.062

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K07053, KAKENHI-PROJECT-17K10294, KAKENHI-PROJECT-18K06460, KAKENHI-PUBLICLY-18H04670, KAKENHI-ORGANIZER-18H05428, KAKENHI-PROJECT-16K15554, KAKENHI-PROJECT-26293261, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277
  • [Journal Article] Microglial production of TNF-alpha is a key element of sustained fear memory.2017

    • Author(s)
      Yu, Z., Fukushima, H., Ono, C., Sakai, M., Kasahara, Y., Kikuchi, Y., Gunawansa, N., Takahashi, Y., Matsuoka, H., Kida, S., Tomita, H.
    • Journal Title

      Brain Behav. Immun.

      Volume: 59 Pages: 313-321

    • DOI

      10.1016/j.bbi.2016.08.011

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-ORGANIZER-24116001, KAKENHI-PLANNED-24116007, KAKENHI-PLANNED-24116008, KAKENHI-PROJECT-26870044, KAKENHI-PROJECT-15H02488
  • [Journal Article] Advanced glycation end products induce brain-derived neurotrophic factor release from human platelets through the Src-family kinase activation2017

    • Author(s)
      Furukawa, K. Fuse, I. Iwakura, Y. Sotoyama, H. Hanyu, O. Nawa, H. Sone, H. Takei, N.
    • Journal Title

      Cardiovascular diabetology

      Volume: 16 Issue: 1 Pages: 20-20

    • DOI

      10.1186/s12933-017-0505-y

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26350885, KAKENHI-PROJECT-16K07053, KAKENHI-PROJECT-15H05787
  • [Journal Article] Perinatal Exposure to Neuregulin-1 Results in Disinhibition of Adult Midbrain Dopaminergic Neurons: Implication in Schizophrenia Modeling2016

    • Author(s)
      Namba H, Okubo T, Nawa H
    • Journal Title

      Scientific Reports

      Volume: 6 Issue: 1 Pages: 22606-22606

    • DOI

      10.1038/srep22606

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-24116010, KAKENHI-PROJECT-25290004
  • [Journal Article] サルやマウスを使った統合失調症のモデル化とその課題2016

    • Author(s)
      那波宏之、斎藤摩美
    • Journal Title

      分子精神医学

      Volume: 16 Pages: 110-117

    • Data Source
      KAKENHI-PLANNED-24116010
  • [Journal Article] Curr Top Behav Neurosci2015

    • Author(s)
      Nagano T, Mizuno M, Morita K, Nawa H
    • Journal Title

      Pathological Implications of Oxidative Stress in Patients and Animal Models with Schizophrenia: The Role of Epidermal Growth Factor Receptor Signaling.

      Volume: Epub ahead of print

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-24116010
  • [Journal Article] Curr Mol Med2015

    • Author(s)
      Kato T, Abe Y, Hirokawa S, Iwakura Y, Mizuno M, Namba H, Nawa H.
    • Journal Title

      Neurobehavioral Differences Between Mice Receiving Distinct Neuregulin Variants as Neonates; Impact on Sensitivity to MK-801.

      Volume: 15 Pages: 222-236

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-24116010
  • [Journal Article] Schisandrin B Ameliorates ICV-Infused Amyloid β Induced Oxidative stress and Neuronal Dysfunction through Inhibiting RAGE/NF-κB/MAPK and Up-regulating HSP/beclin Expression.2015

    • Author(s)
      Vijayasree V. Giridharan, Rajarajan A. Thandavarayan, Somasundaram Arumugam, Makoto Mizuno, Hiroyuki Nawa, Kenji Suzuki, Kam M. Ko, Prasanna Krishnamurthy, Kenichi Watanabe, T Konish.
    • Journal Title

      Pros One

      Volume: 15 Issue: 11 Pages: 1-17

    • DOI

      10.1371/journal.pone.0142483

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460239, KAKENHI-PLANNED-24116010
  • [Journal Article] 統合失調症と炎症性サイトカイン2014

    • Author(s)
      那波宏之 、湯川尊行
    • Journal Title

      生命の科学

      Volume: 65 Pages: 43-47

    • Data Source
      KAKENHI-PLANNED-24116010
  • [Journal Article] A possible link between BDNF and mTOR in control of food intake.2014

    • Author(s)
      Takei N, Furukawa K, Hanyu O, Sone H, Nawa H.
    • Journal Title

      Front Psychol

      Volume: 5 Pages: 1093-1093

    • DOI

      10.3389/fpsyg.2014.01093

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-24116010, KAKENHI-PROJECT-26350885
  • [Journal Article] Increased l1 retrotransposition in the neuroral genome in schizophrenia.2014

    • Author(s)
      Miki Bundo, Manabu Toyoshima, Yohei Okada, Wado Akamatsu, Junko Ueda, Taeko Nemoto-Miyauchi, Fumiko Sunaga, Michihiro Toritsuka, Daisuke Ikawa, Akiyoshi Kakita, Motoichiro Kato, Kiyoto Kasai, Toshifumi Kishimoto, Hiroyuki Nawa, Hideyuki Okano, Takeo Yoshikawa, Tadafumi Katoemail, Kazuya Iwamoto
    • Journal Title

      Neuron

      Volume: 81 Issue: 2 Pages: 306-313

    • DOI

      10.1016/j.neuron.2013.10.053

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0003, KAKENHI-PLANNED-23118004, KAKENHI-PLANNED-23120009, KAKENHI-PROJECT-23390293, KAKENHI-PROJECT-23618010, KAKENHI-PROJECT-23689017, KAKENHI-ORGANIZER-24116001, KAKENHI-PLANNED-24116002, KAKENHI-PLANNED-24116009, KAKENHI-PLANNED-24116010, KAKENHI-PUBLICLY-25110730, KAKENHI-PROJECT-25640038, KAKENHI-PROJECT-25861037
  • [Journal Article] An Attempt of Non-human Primate Modeling of Schizophrenia with Neonatal Challenges of Epidermal Growth Factor2014

    • Author(s)
      Sakai M, Kashiwahara M, Kakita A, Nawa H
    • Journal Title

      J Addict Res Ther

      Volume: 5 Issue: 01 Pages: 170-170

    • DOI

      10.4172/2155-6105.1000170

    • NAID

      120006749407

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-24116010
  • [Journal Article] mTOR signaling and its roles in normal and abnormal brain development.2014

    • Author(s)
      Takei N and Nawa H.
    • Journal Title

      Front Mol Neurosci.

      Volume: 7 Pages: 28-28

    • DOI

      10.3389/fnmol.2014.00028

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25430064, KAKENHI-PROJECT-26350885
  • [Journal Article] mTOR signaling and its roles in normal and abnormal brain development2014

    • Author(s)
      Takei N, Nawa H
    • Journal Title

      Frontiers in Molecular Neuroscience

      Volume: 未定

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-24116010
  • [Journal Article] Elevated postmortem striatal t-DARPP expression in schizophrenia and associations with DRD2/ANKK1 polymorphism2014

    • Author(s)
      Kunii Y, Miura I, Matsumoto J, Hino M, Wada A, Niwa SI, Nawa H, Sakai M, Someya T, Takahashi H, Kakita A, Yabe H.
    • Journal Title

      Prog Neuropsychopharmacol Biol Psychiatry

      Volume: 5846(14)(Epub ahead of print) Pages: 123-128

    • DOI

      10.1016/j.pnpbp.2014.03.014

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23791344, KAKENHI-PLANNED-24116010, KAKENHI-PROJECT-24791220
  • [Journal Article] Neuropathologic implication of peripheral neuregulin-1 and EGF signals in dopaminergic dysfunction and behavioral deficits relevant to schizophrenia: their target cells and time window.2014

    • Author(s)
      Nawa H, Sotoyama H, Iwakura Y, Takei N, Namba H.
    • Journal Title

      Biomed Res Int.

      Volume: n/a Pages: 697935-697935

    • DOI

      10.1155/2014/697935

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-24116010, KAKENHI-PROJECT-25430064
  • [Journal Article] ErbB1-4-dependentEGF/neuregulin signals and their crosstalk in the central nervous system:pathological implications in schizophreniaand Parkinson's disease2013

    • Author(s)
      Iwakura Y, Nawa H
    • Journal Title

      Front CellNeurosci

      Volume: 7 Pages: 4-4

    • Data Source
      KAKENHI-PROJECT-22300107
  • [Journal Article] Exposure to the cytokine EGF leads to abnormal hyperactivity of pallidal GABA neurons: implications for schizophrenia and its modeling.2013

    • Author(s)
      Sotoyama H
    • Journal Title

      J Neurochem

      Volume: 未定 Issue: 4 Pages: 518-528

    • DOI

      10.1111/jnc.12223

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300107, KAKENHI-PROJECT-23500464, KAKENHI-PUBLICLY-23115721, KAKENHI-PLANNED-24116010
  • [Journal Article] Neurobehavioral deficits of epidermal growth factor-overexpressing transgenic mice: impact on dopamine metabolism2013

    • Author(s)
      Eda T, Mizuno M, Araki K, Iwakura Y, Namba H, Sotoyama H, Kakita A, Takahashi H, Satoh H, Chan SY, Nawa H
    • Journal Title

      Neurobehavioral deficits of epidermal growth factor-overexpressing transgenic mice: impact on dopamine metabolism

      Volume: 547 Pages: 21-25

    • DOI

      10.1016/j.neulet.2013.04.055

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-24116010
  • [Journal Article] Exposure to the cytokine EGF leads to abnormalhyperactivity of pallidal GABA neurons:implications for schizophrenia and itsmodeling2013

    • Author(s)
      Sotoyama H, Namba H, Chiken S,Nambu A, Nawa H
    • Journal Title

      J Neurochem

    • Data Source
      KAKENHI-PROJECT-22300107
  • [Journal Article] ErbB inhibitors ameliorate behavioral impairments of an animal model for schizophrenia : implication of their dopamine-modulatory actions2013

    • Author(s)
      Mizuno M, Sotoyama H, Namba H, Shibuya M, Eda T, Wang R, Okubo T, Nagata K, Iwakura Y, Nawa H
    • Journal Title

      Transl Psychiatry

      Volume: 3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500464
  • [Journal Article] ErbB inhibitors ameliorate behavioral impairments of an animal model for schizophrenia: implication of their dopamine-modulatory actions.2013

    • Author(s)
      Mizuno M, Sotoyama H, Namba H, Shibuya M, Eda T, Wang R, Okubo T, Nagata K, Iwakura Y, Nawa H.
    • Journal Title

      Transl Psychiatry.

      Volume: 3 Issue: 4 Pages: e252-e252

    • DOI

      10.1038/tp.2013.29

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500464, KAKENHI-PLANNED-24116010
  • [Journal Article] Experimentalschizophrenia models in rodentsestablished with inflammatory agents andcytokines2012

    • Author(s)
      Nawa H, Yamada K
    • Journal Title

      Methods Mol Biol

      Volume: 829 Pages: 445-451

    • Data Source
      KAKENHI-PROJECT-22300107
  • [Journal Article] In vitro production ofan active neurotrophic factor, neuregulin-1:qualitative comparison of different cell-freetranslation systems2011

    • Author(s)
      Wang R, Iwakura Y, Araki K, SotoyamaH, Takei N, Nawa H
    • Journal Title

      Neurosci Lett

      Volume: 497(2) Pages: 90-93

    • Data Source
      KAKENHI-PROJECT-22300107
  • [Journal Article] In vitro production of an active neurotrophic factor, neuregulin-1 : qualitative comparison of different cell-free translation systems2011

    • Author(s)
      Wang R, Iwakura Y, Araki K, Sotoyama H, Takei N, Nawa H
    • Journal Title

      Neurosci Lett

      Volume: 497 Issue: 2 Pages: 90-93

    • DOI

      10.1016/j.neulet.2011.04.036

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300107
  • [Journal Article] Neuregulin-1 signals from theperiphery regulate AMPA receptorsensitivity and expression in GABAergicinterneurons in developing neocortex2011

    • Author(s)
      Abe Y, Namba H, Kato T, Iwakura Y,Nawa H
    • Journal Title

      JNeurosci

      Volume: 31(15) Pages: 5699-5709

    • Data Source
      KAKENHI-PROJECT-22300107
  • [Journal Article] Molecular characterization and genedisruption of a novel zinc-finger protein,HIT-4, expressed in rodent brain.2010

    • Author(s)
      Tanabe, Y., Hirano, A., Iwasato, T., Itohara S., Araki, A., Yamaguchi, T., Ichikawa, T., Kumanishi T., Aizawa, Y., Takahashi, H., Kakita, A., Nawa, H.
    • Journal Title

      J. Neurochemistry 112

      Pages: 1035-1044

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17018015
  • [Journal Article] Prog Neuropsychopharmacol Biol2009

    • Author(s)
      Zheng Y, Watakabe A, Takada M, Kakita A, Namba H, Takahashi H, Yamamori T, Nawa H.
    • Journal Title

      Psychiatry 15 ; 33(4)

      Pages: 701-706

    • Data Source
      KAKENHI-PROJECT-18390097
  • [Journal Article] Epidermal growth factor administered in the periphery influences excitatory synaptic inputs onto midbrain dopaminergic neurons in postnatal mice2009

    • Author(s)
      Namba H, Zheng Y, Abe Y, Nawa H
    • Journal Title

      Neuroscience 18 ; 158(4)

      Pages: 1731-1741

    • Data Source
      KAKENHI-PROJECT-18390097
  • [Journal Article] In situ hybridization reveals developmental regulation of ErbB1-4 mRNA expression in mouse midbrain : implication of ErbB receptors for dopaminergic neurons2009

    • Author(s)
      Abe Y, Namba H, Zheng Y, Nawa H
    • Journal Title

      Neuroscience (in press)

    • Data Source
      KAKENHI-PROJECT-18390097
  • [Journal Article] The anthraquinone derivative Emodin ameliorates neurobehavioral deficits of a rodent model for schizophrenia2008

    • Author(s)
      Mizuno M, Kawamura H, Takei N, Nawa H
    • Journal Title

      J Neural Transm 115(3)

      Pages: 521-530

    • Data Source
      KAKENHI-PROJECT-18390097
  • [Journal Article] Common behavioral influences of the ErbB1 ligands transforming growth factor alpha and epiregulin administered to mouse neonates2008

    • Author(s)
      Tsuda N, Mizuno M, Yamanaka T, Komurasaki T, Yoshimoto M, Nawa H
    • Journal Title

      Brain Dev 30(8)

      Pages: 533-543

    • NAID

      10025577732

    • Data Source
      KAKENHI-PROJECT-18390097
  • [Journal Article] ヒトの脳機能進化;ゲノム科学と発達脳科学の視点から2007

    • Author(s)
      那波宏之
    • Journal Title

      人工知能学会誌 22

      Pages: 49-53

    • Data Source
      KAKENHI-PROJECT-17018015
  • [Journal Article] The cellular and behavioral consequences of interleukin-1 alpha penetration through the blood-brain barrier of neonatal rats : a critical period for efficacy2007

    • Author(s)
      Tohmi M, Tsuda N, Zheng Y, Mizuno M, Sotoyama H, Shibuya M, Kawamura M, Kakita A, Takahashi H, Nawa H
    • Journal Title

      Neuroscience 30 ; 150(1)

      Pages: 234-250

    • Data Source
      KAKENHI-PROJECT-18390097
  • [Journal Article] In vivo administraton of epidermal growth factor and its homologue attenuated developmental maturation of functional excitatory synapses in cortical GABAergic neurons2007

    • Author(s)
      Nagano T, Namba H, Abe Y, Aoki H, Takei N, Nawa H
    • Journal Title

      Eur J Neurosci 25 ; (2)

      Pages: 380-390

    • Data Source
      KAKENHI-PROJECT-18390097
  • [Journal Article] A cyclooxygenase-2 inhibitor ameliorates behavioral impairments induced by striatal administration of epidermal growth factor2007

    • Author(s)
      Mizuno M, Sotoyama H, Narita E, Kawamura H, Namba H, Zheng Y, Eda T, Nawa H
    • Journal Title

      J Neurosci 19 ; 27(38)

      Pages: 10116-10127

    • Data Source
      KAKENHI-PROJECT-18390097
  • [Journal Article] ヒトの脳機能進化;ゲノム科学と発達脳科学の視点から2007

    • Author(s)
      那波宏之
    • Journal Title

      人工知能学会誌 Vol22

      Pages: 49-53

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17018015
  • [Journal Article] Neonatal exposure to epidermal growth factor induces dopamine D2-like receptor supersensitivity in adult sensorimotor gating2007

    • Author(s)
      Sotoyama H, Namba H, Takei H, Nawa H
    • Journal Title

      Psychopharmacology (Ber1) 191(3)

      Pages: 783-792

    • Data Source
      KAKENHI-PROJECT-18390097
  • [Journal Article] Recent progress in animal modeling of immune inflammatory processes in schizophrenia : implication of specific cytokines.2006

    • Author(s)
      Nawa H, Takei N.
    • Journal Title

      Neurosci Res. 56(1)

      Pages: 2-13

    • NAID

      10018771439

    • Data Source
      KAKENHI-PROJECT-18390097
  • [Journal Article] Recent progress in animal modeling of immune influammatory processes in schizophrenia : implication of specific cytokines2006

    • Author(s)
      Nawa H, Takei
    • Journal Title

      Neurosci Res 56(1)

      Pages: 2-13

    • Data Source
      KAKENHI-PROJECT-18390097
  • [Journal Article] Activity-dependent shedding of heparin-binding EGF-like growth factor in brain neurons2006

    • Author(s)
      Shishido Y, Tanaka T, Piao YS, Araki K, Takei N, Higashiyama S, Nawa H
    • Journal Title

      Biochem Biophys Res Commun 29 ; 348(3)

      Pages: 963-970

    • Data Source
      KAKENHI-PROJECT-18390097
  • [Journal Article] 統合失調症の発達障害伝説とドパミン神経栄養因子2005

    • Author(s)
      那波宏之, 柿田明美
    • Journal Title

      細胞(ニュー・サイエンス社) 37(14)

      Pages: 565-568

    • Data Source
      KAKENHI-PROJECT-13GS0014
  • [Journal Article] 統合失調症の仮説とそのモデル検証(第7回)炎症性サイトカインと統合失調症;複雑な環境・遺伝子相互作用2005

    • Author(s)
      那波宏之, 津田法子, 渡部雄一郎
    • Journal Title

      分子精神医学(先端医学社) 5(3),

      Pages: 301-307

    • NAID

      40006792074

    • Data Source
      KAKENHI-PROJECT-13GS0014
  • [Journal Article] 統合失調症の遺伝子発現プロファイルを用いた脳内病態の解明2004

    • Author(s)
      那波宏之, 入谷修司
    • Journal Title

      医学のあゆみ 208(3)

      Pages: 133-137

    • Data Source
      KAKENHI-PROJECT-16012217
  • [Journal Article] Modulation of brain function by neurotrophins2004

    • Author(s)
      Takei N, Nawa H.
    • Journal Title

      生化学 111(2)

      Pages: 12-12

    • NAID

      10012684913

    • Data Source
      KAKENHI-PROJECT-13GS0014
  • [Presentation] Soliloquy-like self-vocalization of a rat model for schizophrenia and its antipsychotic medication2023

    • Author(s)
      Nawa H、Narihara I
    • Organizer
      第143回日本薬学会年会
    • Data Source
      KAKENHI-PLANNED-18H05429
  • [Presentation] Inflammatory Cytokines in Schizophrenia2022

    • Author(s)
      那波宏之
    • Organizer
      第11回生理研―霊長研―新潟脳研 合同シンポジウム
    • Invited
    • Data Source
      KAKENHI-PLANNED-18H05429
  • [Presentation] 幻聴と幻覚の生物学;統合失調症の診断、治療をめざして2022

    • Author(s)
      那波宏之
    • Organizer
      第90回和歌山医学会総会
    • Invited
    • Data Source
      KAKENHI-PLANNED-18H05429
  • [Presentation] Pitch and duration mismatch negativity of a cytokine-induced rat model for schizophrenia2022

    • Author(s)
      Nawa H
    • Organizer
      The 9th Mismatch Negativity conference in Fukushima
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-18H05429
  • [Presentation] 統合失調症モデルで認められた感覚刺激後に出現する皮質領域間位相同期性の障害2022

    • Author(s)
      難波寿明、稲葉洋芳、那波宏之
    • Organizer
      NEURO 2022
    • Data Source
      KAKENHI-PLANNED-18H05429
  • [Presentation] サイトカインストームと統合失調症;モデル動物研究を踏まえて2022

    • Author(s)
      那波宏之
    • Organizer
      第10回ニューロカンファレンス2022
    • Invited
    • Data Source
      KAKENHI-PLANNED-18H05429
  • [Presentation] Peripheral cytokines at perinatal and prenatal stages perturb neurocognitive development: Implications in schizophrenia2021

    • Author(s)
      那波宏之
    • Organizer
      The Uehara International Symposium 2021 “Brain-periphery interactions in health and diseases”
    • Invited
    • Data Source
      KAKENHI-PLANNED-18H05429
  • [Presentation] ラットを用いた精神疾患モデリングの限界と課題2021

    • Author(s)
      那波宏之
    • Organizer
      第13回ラットトランスレーショナルリサーチ研究会
    • Invited
    • Data Source
      KAKENHI-PLANNED-18H05429
  • [Presentation] Peripheral Cytokines at Perinatal and Prenatal Stages Perturb Neurocognitive Development; Implication in Schizophrenia2021

    • Author(s)
      Hiroyuki Nawa
    • Organizer
      2021 The Uehara International Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K18242
  • [Presentation] ラットを用いた精神疾患モデリングの限界と課題2021

    • Author(s)
      那波宏之
    • Organizer
      第14回ラットリソースリサーチ研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19495
  • [Presentation] 統合失調症に対する動物モデルの現状と課題・展望2021

    • Author(s)
      那波宏之
    • Organizer
      生体機能と創薬シンポジウム2021
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K18242
  • [Presentation] サイトカイン投与統合失調症モデルにおける過覚醒状態でのドパミン神経自発発火活動と音刺激反応性2021

    • Author(s)
      難波寿明、那波宏之
    • Organizer
      第44回日本神経科学大会
    • Data Source
      KAKENHI-PLANNED-18H05429
  • [Presentation] 上皮成長因子はペリニューロナルネットの形成調節を介してGABA神経瀬尾坊の発達抑制に関与する2021

    • Author(s)
      岩倉百合子、小林雄太朗、難波寿明、武井延之、那波宏之
    • Organizer
      第44回日本神経科学大会
    • Data Source
      KAKENHI-PLANNED-18H05429
  • [Presentation] ドパミンD2受容体作動薬キンピロールは、ラットの音周波数逸脱に対するミスマッチ陰性電位様反応を弱める2021

    • Author(s)
      稲葉洋芳、難波寿明、喜田聡、那波宏之
    • Organizer
      第44回日本神経科学大会
    • Data Source
      KAKENHI-PLANNED-18H05429
  • [Presentation] 自由行動ラットにおけるドパミンD2刺激が引き起こすミスマッチ陰性電位様反応変化2021

    • Author(s)
      那波宏之, 難波寿明, 稲葉洋芳
    • Organizer
      第51回日本臨床神経生理学会学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K18242
  • [Presentation] 自由行動ラットにおけるドパミンD2刺激が引き起こすミスマッチ陰性電位様反応変化2021

    • Author(s)
      那波宏之、難波寿明、稲葉洋芳
    • Organizer
      第51回日本臨床生理学会 サテライトシンポジウム 第5回MMN研究会
    • Invited
    • Data Source
      KAKENHI-PLANNED-18H05429
  • [Presentation] ドパミンD2受容体作動薬キンピロールは、ラットの音周波数逸脱に対するミスマッチ陰性電位様反応を弱める2021

    • Author(s)
      稲葉洋芳 , 難波寿明 , 喜田聡 , 那波宏之
    • Organizer
      第44回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-21K18242
  • [Presentation] 統合失調症に対する動物モデルの現状と課題、展望2021

    • Author(s)
      那波宏之
    • Organizer
      生体の機能と創薬シンポジウム2021
    • Invited
    • Data Source
      KAKENHI-PLANNED-18H05429
  • [Presentation] Neurophysiological evaluation of auditory event-related responses in schizophrenia and its animal model2020

    • Author(s)
      那波宏之, 難波寿明、成原格、外山英一、甲斐亮太、稲葉洋芳
    • Organizer
      第43回日本神経科学大会 シンポジウム
    • Invited
    • Data Source
      KAKENHI-PLANNED-18H05429
  • [Presentation] 統合失調症モデル動物研究とその展望;幻聴の再現可能性2020

    • Author(s)
      那波宏之
    • Organizer
      第116回日本精神医学会 特別講演
    • Invited
    • Data Source
      KAKENHI-PLANNED-18H05429
  • [Presentation] 統合失調症患者と動物モデルに共通な聴覚生理反応異常とその評価2020

    • Author(s)
      那波 宏之, 難波 寿明, 成原 格, 外山 英和, 甲斐 竜太, 稲葉 洋芳
    • Organizer
      第43回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-18K19495
  • [Presentation] 統合失調症モデル動物研究とその展望;幻聴の再現可能性2020

    • Author(s)
      那波宏之
    • Organizer
      第116回日本精神神経学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19495
  • [Presentation] 統合失調症の母体感染モデルにおける軸索身長・ガイダンスシグナルの分析2020

    • Author(s)
      岩倉百合子、小林雄太朗、那波宏之
    • Organizer
      第43回日本神経科学大会 ポスター発表
    • Data Source
      KAKENHI-PLANNED-18H05429
  • [Presentation] Persistent hyper-active VTA dopamine neurons lead to social deficits2019

    • Author(s)
      外山英和、那波宏之
    • Organizer
      NEURO2019
    • Data Source
      KAKENHI-PROJECT-17H04030
  • [Presentation] 統合失調症の動物モデル化の苦難2019

    • Author(s)
      那波宏之
    • Organizer
      第49回日本臨床神経生理学会学術大会
    • Invited
    • Data Source
      KAKENHI-PLANNED-18H05429
  • [Presentation] 統合失調症モデルラット硬膜上脳波の聴覚事象関連電位の感覚ゲーティングに伴うβ帯 域の変動2019

    • Author(s)
      那波宏之、稲葉洋芳、外山英和 、難波寿明
    • Organizer
      次世代脳、冬のシンポジウム
    • Data Source
      KAKENHI-PUBLICLY-18H04938
  • [Presentation] 統合失調症の動物モデル化の苦難;分子生物学から神経病態生理学を用いて2019

    • Author(s)
      那波宏之
    • Organizer
      日本臨床神経生理学会
    • Data Source
      KAKENHI-PUBLICLY-18H04938
  • [Presentation] MMN測定法を用いたモデル動物の幻聴・錯聴評価の可能性2019

    • Author(s)
      那波宏之
    • Organizer
      第2回MMN研究会、平成31年2月2日、コラッセ福島
    • Data Source
      KAKENHI-PUBLICLY-18H04938
  • [Presentation] 統合失調症の動物モデル化の苦難;分子生物学から神経病態生理学を用いて2019

    • Author(s)
      那波宏之
    • Organizer
      日本臨床神経生理学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19495
  • [Presentation] A schizophrenia rat model induced by an inflammatory cytokine exhibits abnormal beta synchronization to auditory steady-state stimuli2019

    • Author(s)
      Hiroyoshi Inaba, Kohei Koide, Yuta Hattori, Hisaaki Namba, Hidekazu Sotoyama, Hiroyuki Nawa
    • Organizer
      Neural Oscillation Conference 2019
    • Data Source
      KAKENHI-PUBLICLY-18H04938
  • [Presentation] Auditory mismatch responses to duration deviants in awake rats; tone frequency dependence and gamma power involvement2019

    • Author(s)
      Hiroyoshi Inaba, Hidekazu Sotoyama, Itaru Narihara, Hisaaki Namba, Eiichi Jodo, Satoshi Eifuku, Hirooki Yabe, Hiroyuki Nawa
    • Organizer
      NEURO2019
    • Data Source
      KAKENHI-PUBLICLY-18H04938
  • [Presentation] Interaction of three monoaminergic neurons in social stress responses2019

    • Author(s)
      鬼川真季,、外山英和、難波寿明、 那波宏之
    • Organizer
      NEURO2019
    • Data Source
      KAKENHI-PROJECT-17H04030
  • [Presentation] Dopamine Dysfunction in Schizophrenia and Its Animal Model2019

    • Author(s)
      那波宏之
    • Organizer
      McGovern Institute Seminar in Tsinghua University
    • Invited
    • Data Source
      KAKENHI-PLANNED-18H05429
  • [Presentation] ネズミも精神病にかかる?;統合失調症と動物モデル2018

    • Author(s)
      那波宏之
    • Organizer
      第10回脳科学クラスター・ミニリトリート(徳島大学)
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04030
  • [Presentation] 炎症性サイトカイン誘発性統合失調症モデルにおける社会性行動異常の分子基盤2018

    • Author(s)
      外山英和、那波宏之
    • Organizer
      次世代脳プロジェクト
    • Data Source
      KAKENHI-PLANNED-18H05429
  • [Presentation] 幻聴・幻覚はどうして起きるのか?2018

    • Author(s)
      那波宏之
    • Organizer
      日本神経化学会若手育成セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19495
  • [Presentation] Delirium-like motor behaviors induced by the negative alert voice in a rat model for schizophrenia2018

    • Author(s)
      Hiroyyuki NAWA
    • Organizer
      国際幻聴コンソーシアム京都, 京都大学、平成30年10月18日
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19495
  • [Presentation] Neuropathologic implication of pallidal hyperactivity in the auditory abnormality of schizophrenia animal models2017

    • Author(s)
      Hiroyuki Nawa
    • Organizer
      The 13th World Congress of Biological Psychiatry
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04030
  • [Presentation] Postpubertal impairments of auditory processing in a cytokine-induced schizophrenia model2016

    • Author(s)
      Hiroyuki NAWA
    • Organizer
      International Symposium on Microendophenotype on psychiatric disorders
    • Place of Presentation
      横浜ワールドポータース(神奈川県横浜市)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-24116010
  • [Presentation] 統合失調症のサイトカインモデにおける大脳基底核間接路の変調2016

    • Author(s)
      Hiroyuki NAWA
    • Organizer
      Basal Ganglia in Health and Disease
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-07-10
    • Invited
    • Data Source
      KAKENHI-PLANNED-24116010
  • [Presentation] 思春期以降に幻聴・幻覚を発病するかもしれないモデル動物2016

    • Author(s)
      那波宏之
    • Organizer
      第59回日本神経化学会大会
    • Place of Presentation
      福岡国際会議場(福岡県福岡市)
    • Year and Date
      2016-09-08
    • Invited
    • Data Source
      KAKENHI-PLANNED-24116010
  • [Presentation] Postpubertal impairments of auditory processing in a cytokine-induced schizophrenia model2016

    • Author(s)
      Hisaaki Namba, Takeshi Okubo, Hiroyuki Nawa
    • Organizer
      DOPAMINE2016
    • Place of Presentation
      Vienna Austria
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-24116010
  • [Presentation] Perinatal exposure to neuregulin-1 enhances firing activity of mature dopaminergic neurons in the substantia nigra2016

    • Author(s)
      H. NAMBA, T. OKUBO, H. NAWA
    • Organizer
      DOPAMINE 2016
    • Place of Presentation
      Vienna, Austria
    • Year and Date
      2016-09-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25290004
  • [Presentation] 最終糖化産物(AGE)はヒト血小板からSrc family kinaseの活性を介してBDNFの放出を促進させる.2016

    • Author(s)
      古川和郎、武井延之、岩倉百合子、外山英和、羽入修、布施一郎、那波宏之、曽根博仁.
    • Organizer
      第59回日本糖尿病学会年次学術集会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Data Source
      KAKENHI-PROJECT-26350885
  • [Presentation] Abnormal firing activity of midbrain dopaminergic neurons of a schizophrenia animal model established by perinatal EGF treatment2016

    • Author(s)
      Hidekazu Sotoyama, Hiroyuki Nawa
    • Organizer
      DOPAMINE2016
    • Place of Presentation
      Vienna Austria
    • Year and Date
      2016-09-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-24116010
  • [Presentation] Abnormal firing activity of midbrain dopaminergic neurons of a schizophrenia animal model established by perinatal EGF treatment2016

    • Author(s)
      H. SOTOYAMA, H. NAWA
    • Organizer
      DOPAMINE 2016
    • Place of Presentation
      Vienna, Austria
    • Year and Date
      2016-09-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25290004
  • [Presentation] サイトカインを用いた統合失調症モデリングとその課題2015

    • Author(s)
      那波宏之
    • Organizer
      JSTさきがけシンポジウム「脳情報の解読と制御」
    • Place of Presentation
      新潟大学 (新潟県、新潟市)
    • Year and Date
      2015-11-10
    • Invited
    • Data Source
      KAKENHI-PLANNED-24116010
  • [Presentation] Impact of circulating neuregulin-1 and EGF on brain circuit development and maintenance; Implication in schizophrenia2015

    • Author(s)
      Hiroyuki Nawa
    • Organizer
      第1回Neuroscience Network in Kobe
    • Place of Presentation
      神戸大学
    • Year and Date
      2015-02-06
    • Invited
    • Data Source
      KAKENHI-PLANNED-24116010
  • [Presentation] サイトカインモデルを使った非定型抗精神病薬の作用 機序の解明2015

    • Author(s)
      那波宏之、難波寿明、外山英和
    • Organizer
      応用薬理学学会
    • Place of Presentation
      新潟大学 (新潟県、新潟市)
    • Year and Date
      2015-09-04
    • Invited
    • Data Source
      KAKENHI-PLANNED-24116010
  • [Presentation] Neuroinflammatory features of the cytokine-induced animal model for schizophrenia; implication of the regional specificity2015

    • Author(s)
      Hiroyuki Nawa, Hiroaki Tsukano, Katsuei Shibuki, Akiyoshi Kakita, Hidekazu Sotoyama, Hisaaki Namba
    • Organizer
      第58回日本神経化学大会 シンポジウム
    • Place of Presentation
      ソニック大宮 (埼玉県、大宮市)
    • Year and Date
      2015-09-10
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-24116010
  • [Presentation] 青年期前後での中脳ドパミン神経自発活動変化と新生仔期上皮成長因子投与の影響2015

    • Author(s)
      Namba H, Tomiyama K, Onishi S, Nawa H
    • Organizer
      第38回日本神経科学大会
    • Place of Presentation
      神戸国際会議場(兵庫県、神戸市)
    • Year and Date
      2015-07-28
    • Data Source
      KAKENHI-PROJECT-25290004
  • [Presentation] 統合失調症の現状と課題2014

    • Author(s)
      那波宏之
    • Organizer
      平成26年度 新潟精神医学会 総会
    • Place of Presentation
      新潟市 ANAクラウンプラザホテル
    • Year and Date
      2014-10-25
    • Invited
    • Data Source
      KAKENHI-PLANNED-24116010
  • [Presentation] Pathophysiological alterations of in vivo activity and intrinsic property of mature dopaminergic neuron in the epidermal growth factor-administered mice as neonate.2013

    • Author(s)
      難波寿明、那波宏之
    • Organizer
      Dopamine2013
    • Place of Presentation
      イタリア(アルゲーロ)
    • Data Source
      KAKENHI-PROJECT-23500464
  • [Presentation] 2種の幼若期栄養因子投与マウスのin vivo麻酔下での中脳ドパミン神経活動変化 (Abnormal firing activities of the midbrain dopaminergic neurons in the mice treated with EGF and neuregulin-1 as neonate.)2013

    • Author(s)
      難波寿明、大久保猛司、那波宏之
    • Organizer
      第36回日本神経科学大会(Neuro2013)
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23500464
  • [Presentation] 上皮成長因子によって確立された統合失調症動物モデルにおける腹側被蓋野-前頭皮質ドパミン経路の機能異常 (Abnormal ventral tegmental area - medial prefrontal cortex dopaminergic pathway of the schizophrenia animal model established by epidermal growth factor)2013

    • Author(s)
      外山英和 難波寿明 那波宏之
    • Organizer
      第36回日本神経科学大会(Neuro2013)
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23500464
  • [Presentation] 上皮成長因子によって確立された統合失調症動物モデルにおける腹側被蓋野-前頭皮質経路の機能異常(Abnormal ventral tegmental area - medial prefrontal cortex dopaminergic pathway of the schizophrenia animal model established by epidermal growth factor)2013

    • Author(s)
      外山英和, 難波寿明, 那波宏之
    • Organizer
      第36回日本神経科学大会(Neuro2013)
    • Place of Presentation
      京都
    • Year and Date
      2013-06-22
    • Data Source
      KAKENHI-PROJECT-23500464
  • [Presentation] Perinatal exposure to the cytokine EGF produces pallidal hyperinnervation of dopaminergic neurons and the indirect pathway dysfunction in the schizophrenia animal model2013

    • Author(s)
      Nawa H, Sotoyama H, Namba H
    • Organizer
      DOPAMINE 2013
    • Place of Presentation
      アルゲーロ、イタリア
    • Invited
    • Data Source
      KAKENHI-PLANNED-24116010
  • [Presentation] 2 種の幼若期栄養因子投与マウスの in vivo麻酔下での中脳ドパミン神経活動変化( Abnormal firing activities of the midbrain dopaminergic neurons in the mice treated with EGF and neuregulin-1 as neonate.)2013

    • Author(s)
      難波寿明, 大久保猛司, 那波宏之
    • Organizer
      第36回日本神経科学大会(Neuro2013)
    • Place of Presentation
      京都
    • Year and Date
      2013-06-22
    • Data Source
      KAKENHI-PROJECT-23500464
  • [Presentation] Pallidal hyperdopaminergic innervation induced by neonatal exposure to epidermal growth factor; implication in schizophrenia2012

    • Author(s)
      Nawa H
    • Organizer
      Asian-Pacific Society for Neurochemistry
    • Place of Presentation
      Kobe, JAPAN
    • Year and Date
      2012-09-29
    • Data Source
      KAKENHI-PLANNED-24116010
  • [Presentation] Pallidal hyperdopaminergic innervation induced by neonatal exposure to epidermal growth factor; implication in schizophrenia2012

    • Author(s)
      Nawa H
    • Organizer
      Asian-Pacific Society for Neurochemistry
    • Place of Presentation
      Kobe
    • Data Source
      KAKENHI-PROJECT-22300107
  • [Presentation] Pallidal hyperdopaminergicinnervation induced by neonatal exposureto epidermal growth factor; implication inschizophrenia2012

    • Author(s)
      Nawa H, Namba H, Iwakura Y, Takei N, Sotoyama H
    • Organizer
      The 11^<th> Biennial Metting of APSN
    • Place of Presentation
      Kobe JAPAN.
    • Data Source
      KAKENHI-PROJECT-22300107
  • [Presentation] Neurotrophic interaction of midbrain dopaminergicneurons with EGF and neuregulin-1;implication in schizophrenia2012

    • Author(s)
      Nawa H, Iwakura Y
    • Organizer
      The Bit's 3rdAnnual World Congree of NeuroTalk-2012
    • Place of Presentation
      Beijin CHINA.
    • Data Source
      KAKENHI-PROJECT-22300107
  • [Presentation] 幼若期ニューレグリン投与マウスにおける中脳ドパミン神経の生理特性( Electrophysiological properties of adult midbrain dopaminergic neurons of the mice treated with neuregulin-1 as neonates.)2011

    • Author(s)
      難波寿明, 竹田悠亮, 那波宏之
    • Organizer
      第34回日本神経科学大会
    • Place of Presentation
      横浜
    • Year and Date
      2011-09-16
    • Data Source
      KAKENHI-PROJECT-23500464
  • [Presentation] Pallidal hyoerdopaminergic states and PPI deficitsinduced byperipheral challenge ofepidermal growth factor to rat neonates2011

    • Author(s)
      Sotoyama H, Zheng Y, Mizuno M,AizawaY, Abe Y, Ishizuka R, Wang R,Iwakura Y, Nawa H
    • Organizer
      The 41st Annual Meeting of Society for thNeuroscience
    • Place of Presentation
      Washington DC, USA.
    • Data Source
      KAKENHI-PROJECT-22300107
  • [Presentation] 幼若期ニューレグリン投与マウスにおける中脳ドパミン神経の生理特性2011

    • Author(s)
      難波寿明、竹田悠亮、那波宏之
    • Organizer
      第34回日本神経科学学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23500464
  • [Presentation] 神経細胞ではAMPKが成長因子によるmTORCシグナル活性化と蛋白合成促進をドミナントに制御する2010

    • Author(s)
      武井延之、石塚佑太、那波宏之
    • Organizer
      第33回日本分子神経生物学会・第83回日本生化学会大会・合同大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-22300107
  • [Presentation] Neurotrophic contributionofEGF and neuregulin-1to Parkinson'sdisease and schizophrenia2010

    • Author(s)
      Nawa H
    • Organizer
      Japan-KoreaJoint Conference on Brain Aging and Neurodegeneration
    • Place of Presentation
      Nagasaki JAPAN
    • Data Source
      KAKENHI-PROJECT-22300107
  • [Presentation] 新生仔期ニューレグリン1-ベータ1暴露は成熟後のMK801感受性を増強する2008

    • Author(s)
      加藤泰介、水野誠、那波宏之
    • Organizer
      第51回日本神経化学会大会
    • Place of Presentation
      富山
    • Year and Date
      2008-09-12
    • Data Source
      KAKENHI-PROJECT-18390097
  • [Presentation] Neuregulin-1 enhances glutamatergic synapse maturation of GABAergic interneuron in developing neocortex2008

    • Author(s)
      Abe Y., Namba H, Takei H, Nawa H
    • Organizer
      38th Annual Meeting of Sociey for Neuroscience
    • Place of Presentation
      Washington DC
    • Data Source
      KAKENHI-PROJECT-18390097
  • [Presentation] ニューレグリン・EGFシグナル阻害剤が有する抗精神病活性2008

    • Author(s)
      那波宏之、加藤泰介、阿部祐一、外山英和、難波寿明、水野誠
    • Organizer
      第51回日本神経化学会大会
    • Place of Presentation
      富山
    • Year and Date
      2008-09-12
    • Data Source
      KAKENHI-PROJECT-18390097
  • [Presentation] 脳発達障害のモデル研究 ; サイトカインの関与2008

    • Author(s)
      那波宏之
    • Organizer
      第38回新潟神経学夏季セミナー
    • Place of Presentation
      新潟
    • Year and Date
      2008-08-29
    • Data Source
      KAKENHI-PROJECT-18390097
  • [Presentation] イボテン酸投与統合失調症モデルラットにおけるチロシン受容体阻害剤の効果2008

    • Author(s)
      水野誠、鄭英君、川村宏樹、渋谷雅子、朴英善、外山英和、江田岳誉、那波宏之
    • Organizer
      第51回日本神経化学会大会
    • Place of Presentation
      富山
    • Year and Date
      2008-09-13
    • Data Source
      KAKENHI-PROJECT-18390097
  • [Presentation] ErbB1受容体リガンドは大脳皮質ニューロンの前シナプス発達を阻害する2008

    • Author(s)
      那波宏之、武井延之、柿田明美、高橋均、横幕大作
    • Organizer
      第31回日本神経科学学会
    • Place of Presentation
      東京
    • Year and Date
      2008-07-10
    • Data Source
      KAKENHI-PROJECT-18390097
  • [Presentation] 新生期上皮成長因子によるドーパミンD2受容体感受性の亢進と大脳基底核GABA作動性路に対する影響2008

    • Author(s)
      外山英和、那波宏之
    • Organizer
      第51回日本神経化学会大会
    • Place of Presentation
      富山
    • Year and Date
      2008-09-12
    • Data Source
      KAKENHI-PROJECT-18390097
  • [Presentation] Molecular and behavioral analyses of a non-human primate model for schizophrenia2008

    • Author(s)
      Nawa, H.
    • Organizer
      第31回日本分子生物学会+第81回日本生化学会合同年会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-17018015
  • [Presentation] Molecular and behavioral analyses of a non-human primate model for schizophrenia2008

    • Author(s)
      Hiroyuki Nawa
    • Organizer
      第31回日本分子生物学会年会/第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸市
    • Year and Date
      2008-12-12
    • Data Source
      KAKENHI-PROJECT-18390097
  • [Presentation] Molecular and behavioral analyses of a non-human primate model for schizophrenia2008

    • Author(s)
      Nawa H
    • Organizer
      第31回日本分子生物学会年会/第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-12
    • Data Source
      KAKENHI-PROJECT-18390097
  • [Presentation] Epidermal Growth Factor Challenge to A Cynomolgus Monkey Neonate and Its Behavioral Consequences.2008

    • Author(s)
      Hiroyuki Nawa
    • Organizer
      The 2^<nd> WFSBP Asia-Paciifc Congress
    • Place of Presentation
      富山市
    • Year and Date
      2008-07-11
    • Data Source
      KAKENHI-PROJECT-18390097
  • [Presentation] ニューレグリンー1・ErbB4慢性刺激による皮質パルアルブミン陽性細胞のグルタミン作動性シナプスに及ぼす影響2008

    • Author(s)
      阿部祐一、難波寿明、尾崎美和子、那波宏之
    • Organizer
      第31回日本神経科学学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-18390097
  • [Presentation] Epidermal Growth Factor Challenge to A Cynomolgus Monkey Neonate and Its Behavioral Consequences2008

    • Author(s)
      Nawa H
    • Organizer
      The 2nd WESBF Asia-Paciifc Congress
    • Place of Presentation
      富山
    • Year and Date
      2008-07-11
    • Data Source
      KAKENHI-PROJECT-18390097
  • [Presentation] 統合失調症の網羅的分子病態にみられた脳内炎症以上を分子標的とする創薬への試み2007

    • Author(s)
      那波宏之
    • Organizer
      第15回日本精神行動遺伝医学会
    • Place of Presentation
      国立精神神経センター
    • Year and Date
      2007-11-17
    • Data Source
      KAKENHI-PROJECT-18390097
  • [Presentation] 統合失調症の網羅的分子病態にみられた脳内炎症以上を分子標的とする創薬への試み2007

    • Author(s)
      那波宏之
    • Organizer
      第15回日本精神行動遺伝医学会
    • Place of Presentation
      国立精神神経センター, 小平
    • Year and Date
      2007-11-17
    • Data Source
      KAKENHI-PROJECT-18390097
  • [Presentation] ErbB1遺伝子改変動動物の作製および行動解析2007

    • Author(s)
      今野公博、熊谷春乃、荒木一明、糸原重美、那波宏之
    • Organizer
      第50回日本神経化学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18390097
  • [Presentation] 統合失調症モデルの認知行動機能障害に対するエモジンの効果2007

    • Author(s)
      川村宏樹、水野誠、那波宏之
    • Organizer
      第50回日本神経化学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18390097
  • [Presentation] Neonatal exposure to neuregulin-1 results in distinct behavioral abnormalities in mice ; Comparisn with other cytokine treatments2007

    • Author(s)
      Nawa H, Kato T, Abe Y, Mizuno M, Araki K, Takei N, Ozaki M
    • Organizer
      Int Schizophrenia Congress
    • Place of Presentation
      Colorado Spring
    • Data Source
      KAKENHI-PROJECT-18390097
  • [Presentation] EGF receptor expression of nigral dopamine neurons in human and monkey ; impact on Parkinsonism2007

    • Author(s)
      Zheng Y, Iwakura Y, Takada M, Namba H, Takei N, Kakita A, Takahashi H, Nawa H
    • Organizer
      The 37th Society for Neuroscience Meeting
    • Place of Presentation
      San Diego
    • Data Source
      KAKENHI-PROJECT-18390097
  • [Presentation] 幼若期上皮成長因子投与マウスの前頭皮質、海馬におけるGABA抑制機能の低下2007

    • Author(s)
      難波寿明、阿部祐一、那波宏之
    • Organizer
      第30回日本神経科学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18390097
  • [Presentation] Minocycline improves cognitive and behavioral impairments resulted from neonatal exposure to interleukin-12007

    • Author(s)
      Tsuda N, Eda T, Mizuno M, Sotoyama H, Nawa H
    • Organizer
      The 37th Society for Neuroscience Meeting
    • Place of Presentation
      San Diego
    • Data Source
      KAKENHI-PROJECT-18390097
  • [Presentation] Effects of emodijn for behavioral impairment in models of schizophrenia2007

    • Author(s)
      Mizuno M, Kawamura H, Nawa H
    • Organizer
      38th Annual Meeting of Society for Neuroscience
    • Place of Presentation
      Washington DC
    • Data Source
      KAKENHI-PROJECT-18390097
  • [Presentation] Striatal epidermal growth factor signals influences dopamine metabolism and functins2006

    • Author(s)
      Mizuno M, Narita E, Kawamura H, Eda T, Nawa H
    • Organizer
      Soc. Neurosci. Abstr
    • Place of Presentation
      Atlanta(589.7)
    • Data Source
      KAKENHI-PROJECT-18390097
  • [Presentation] Neonatal administration of ErbB1 ligands commoly induce postpubertal cognitive behavioral change2006

    • Author(s)
      Tsuda N, Mizuno M, Nawa H
    • Organizer
      Soc. Neurosci. Abstr
    • Place of Presentation
      Atlanta(687.5)
    • Data Source
      KAKENHI-PROJECT-18390097
  • [Presentation] In vivo Action of ErbB ligands on synaptic development and neurobehavioral consequences ; Implication in schizophrenia2006

    • Author(s)
      Nawa H, Kato T, Tsuda N, Mizuno M, Takei N, Ozaki M, Yokomaku D
    • Organizer
      APSN
    • Place of Presentation
      Singapore
    • Data Source
      KAKENHI-PROJECT-18390097
  • [Presentation] Striatal infusion of EGF promotes proliferation of neural stem cells and affects behavioral traits2006

    • Author(s)
      narita E, Mizuno M, Eda T, Kakita A, Nawa H
    • Organizer
      The 49th Japan Neurochemistry Socirty Annual Meeting
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-18390097
  • [Presentation] Striatal epidermal growth factor receptor activation on dopamine metabolism and functions2006

    • Author(s)
      Mizuno M, Narita E, Kawamura H, Eda T, Nawa H
    • Organizer
      The 49th Japan Neurochemistry Society Annual Meeting
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-18390097
  • [Presentation] Neonatal exposure to EGF receptor ligands commonly produces later behavioral impairments in mice2006

    • Author(s)
      Tsuda N, Mizuno M, Komurasaki T, Yoshimoto M, Nawa H
    • Organizer
      The 49th Japan Neurochemistry Society Annual Meeting
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-18390097
  • [Presentation] Postnatal ErbB1 stimulation potentiates excitatory synaptic inputs to midbrain dopaminergic neurons2006

    • Author(s)
      Namba H, Zheng Y, Nawa H
    • Organizer
      Soc. Neurosci. Abstr
    • Place of Presentation
      Atlanta(341.7)
    • Data Source
      KAKENHI-PROJECT-18390097
  • [Presentation] Impact of circulating neuregulin-1 and EGF on brain circuit development and maintenance; Implication in schizophrenia

    • Author(s)
      Nawa H
    • Organizer
      The 5th Nagasaki-Hallym Joint Meeting on Neurobiology adn Brain Aging
    • Place of Presentation
      長崎
    • Invited
    • Data Source
      KAKENHI-PROJECT-25290004
  • [Presentation] Impact of circulating neuregulin-1 and EGF on brain circuit development and maintenance; Implication in schizophrenia

    • Author(s)
      Nawa H
    • Organizer
      The 5th Nagasaki-Hallym Joint Meeting on Neurobiology adn Brain Aging
    • Place of Presentation
      長崎
    • Invited
    • Data Source
      KAKENHI-PLANNED-24116010
  • [Presentation] Neuropathological impact of peripheral cytokines on dopaminergic development and neocortical aging, implication for schizophrenia

    • Author(s)
      Hiroyuki Nawa
    • Organizer
      Asian Aging Symposium
    • Place of Presentation
      大阪大学中ノ島センター(大阪市)
    • Year and Date
      2015-03-14 – 2015-03-15
    • Invited
    • Data Source
      KAKENHI-PROJECT-25290004
  • [Presentation] Animal modeling of schizophrenia with cytokines; its application to drug development

    • Author(s)
      Nawa H, Mizuno M
    • Organizer
      Neuro2013 公開シンポジウム
    • Place of Presentation
      京都
    • Invited
    • Data Source
      KAKENHI-PLANNED-24116010
  • [Presentation] Vulnerability of dopaminergic development to cytokines and its implication of the D2R-dependent indirect pathway in schizophrenia

    • Author(s)
      Nawa H, Namba H, Sotoyama H,
    • Organizer
      WFSBP
    • Place of Presentation
      京都
    • Invited
    • Data Source
      KAKENHI-PLANNED-24116010
  • [Presentation] Impact of circulating neuregulin-1 and EGF on brain circuit development and maintenance; Implication in schizophrenia

    • Author(s)
      Nawa H
    • Organizer
      WFSBP-Neuro2013 Joint Symposium
    • Place of Presentation
      京都
    • Invited
    • Data Source
      KAKENHI-PLANNED-24116010
  • [Presentation] Vulnerability of dopaminergic development to cytokines and its implication of the D2R-dependent indirect pathway in schizophrenia

    • Author(s)
      Nawa H, Namba H, Sotoyama H
    • Organizer
      国際生物学的精神医学会
    • Place of Presentation
      京都
    • Invited
    • Data Source
      KAKENHI-PROJECT-25290004
  • [Presentation] サイトカインによる脳神経マイクロエンドフェノタイプ変換;統合失調症とそのモデル研究より

    • Author(s)
      那波宏之
    • Organizer
      包括脳ネットワーク 5領域合同シンポジウム
    • Place of Presentation
      東京医歯科大学
    • Year and Date
      2014-12-11 – 2014-12-13
    • Invited
    • Data Source
      KAKENHI-PLANNED-24116010
  • [Presentation] Peri-adolescent spike elevation of dopaminergic neurons in a cytokine-induced schizophrenia model; implication for the temporal specificity of the onset

    • Author(s)
      Hisaaki Namba, Katsutoshi Tomiyama, Shunsuke Onishi, Hiroyuki Nawa
    • Organizer
      The 38th Annual Meeting of the JAPAN Neuroscience Society
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Year and Date
      2015-07-28 – 2015-07-31
    • Data Source
      KAKENHI-PROJECT-25290004
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