Umemura Takashi 梅村隆志

… Alternative Names

UMEMURA Takashi 梅村隆志

UMEMURA takashi 梅村隆史

梅村隆志ウメムラタカシ

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Researcher Number	50185071
Other IDs
Affiliation (Current)	2025: ヤマザキ動物看護大学, 動物看護学部, 教授 2025: 国立医薬品食品衛生研究所, 病理部, 客員研究員
Affiliation (based on the past Project Information) *help	2018 – 2021: ヤマザキ動物看護大学, 動物看護学部, 教授 2017: ヤマザキ学園大学, 動物看護学部, 教授 2015 – 2016: 国立医薬品食品衛生研究所, 病理部, 室長 2007 – 2012: National Institute of Health Sciences, Division of Pathology, Section Chief 2005 – 2006: 国立医薬品食品衛生研究所, 病理部, 主任研究官 … More 2003: National Institute of Health Sciences, Division of Pathology, Senior Scientist, 病理部, 主任研究官 1997: 国立医薬品食品衛生研究所, 安全性生物試験研究センター・毒性部, 主任研究官 1996: 国立衛生試験所, 安全性生物試験研究センター・毒性部, 主任研究官 1996: 国立衛生試験所, 毒性部, 主任研究官 Less
Review Section/Research Field	Principal Investigator Basic Section 42040:Laboratory animal science-related / Veterinary medical science Except Principal Investigator Experimental pathology / Drug development chemistry / 広領域
Keywords	Principal Investigator Notchシグナル / Nrf2 / 肝再生 / Notch4 / 増殖シグナル / Notch / 肝再生結節 / 持続性肝再生 / 部分肝切除 / 結節性再生性肝細胞過形成 … More / 肝細胞腫瘍 / 転写因子Nrf2 / Stat3 / 慢性増殖刺激 … More Except Principal Investigator サイトカイン / 遺伝子改変動物 / 活性酸素 / ポリフェノール / 酸化ストレス / カテキン / 抗酸化剤 / サブユニット構造 / サイトカイン受容体 / chemoorevention / oxidatiye stress / reactive oxygen species / polyphenol / flavonoid / catechin / antioxidant / アポトーシス / 予防物質 / フラボノイド / tumor suppressor gene / hydroxynonenal / oxidative DNA damage / lipid peroxidation / mechanism / molecular / transgenic animals / endogenous carcinogenesis / reporter gene / 8-OHdG / 四塩化炭素 / アクロレイン / がん抑制遺伝子 / ヒドロキシノネナール / 酸化的DNA障害 / 脂質過酸化 / 分子機構 / 内的発がん / レポーター遺伝子 / gene mutation / developmental toxicity / Embryonic stem cell / 突然変異検出系 / 分化 / 遺伝子突然変異 / 発生傷害 / 胚幹細胞 / hematopoietic progenitor cells / TGF-β / sytokine / p53-deficient mice / 骨髄造血前駆細胞 / TGFβ / P53欠失マウス / レスベートロール / アルツハマー / アルツハイマー / 生活習慣病 / ビタミンE / アルツハイマー病 Less

Nrf2/Notch signal pathways contributing to ON/OFF regulation in sustained livre regenerationPrincipal Investigator
- Principal Investigator
  
  Umemura Takashi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Yamazaki University of Animal Nursing
Possible involvement of Nrf2 in breakdown of liver regeneration programPrincipal Investigator
- Principal Investigator
  
  Umemura Takashi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Veterinary medical science
- Research Institution
  Yamazaki Gakuen University
  National Institute of Health Sciences
Studies on synthetic antioxidants for prevention of oxidative stress-related diseases
- Principal Investigator
  
  FUKUHARA Kiyoshi
- Project Period (FY)
  2008 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  National Institute of Health Sciences
Design and Synthesis of Antioxidant for a New Type of Chemopreventive Agents
- Principal Investigator
  
  KIYUOSHI Fukuhara
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  National Institute of Health Sciences
Studies on molecular mechanisms underlying endogenous carcinogenesis using transgenic reporter genes as internal probes
- Principal Investigator
  
  NISHIKAWA Akiyoshi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  National Institute of Health Sciences
薬剤評価モデルとしてのヒト型造血因子受容体遺伝子導入マウスとその造血幹細胞動態制御
- Principal Investigator
  
  井上達
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  国立衛生試験所
遺伝子改変動物の造血幹細胞動態制御を指標としたサイトカイン系薬剤評価モデルの開発
- Principal Investigator
  
  INOUE Tohru
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  国立衛生試験所
Signal transduction mediated by hematopoietic factors and TGF-β in p53-deficient mice
- Principal Investigator
  
  INOUE Tohru
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  National Institute of Health Sciences
Construction of mouse embryonic stem cells for the detection of gene mutation
- Principal Investigator
  
  INOUE Tohru
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  広領域
- Research Institution
  National Institute of Health Sciences

All 2021 2019 2017 2012 2011

All Journal Article Presentation

[Journal Article] Molecular Pathological Differences in Global Gene Expression between Two Sustained Proliferative Lesions, Nodular Regenerative Hepatocellular Hyperplasia and Hepatocellular Adenoma, in Mice.2019
- Author(s)
  Takasu S, Yokoo Y, Ishii Y, Kijima A, Ogawa K, Umemura T.
- Journal Title
  
  Toxicolic Pathology
  
  Volume: 47 Issue: 1 Pages: 44-52
- DOI
  10.1177/0192623318810200
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06042
[Journal Article] Determination of Lusidin-specific DNA adducts by liquid chromatography with tandem mass spectrometry in the livers and kidneys of rats given Lucidin-3-O-primeveroside2012
- Author(s)
  Y. Ishii, K. Inoue, S. Takasu, M. Jin, K. Matsushita, K. Kuroda, K. Fukuhara, A. Nishikawa, T. Umemura
- Journal Title
  
  Chem. Res. Toxicol
  
  Volume: 25 Issue: 5 Pages: 1112-1118
- DOI
  10.1021/tx300084p
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390038
[Journal Article] Detection and quantification of specific-DNA adducts by LC-MS/MS in the livers of rats given estragole at the carcinogenic dose2011
- Author(s)
  Y. Ishii, Y, Suzuki, D. Hibi, M. Jin, K. Fukuhara, T. Umemura, A. Nishikawa
- Journal Title
  
  Chem. Res. Toxico
  
  Volume: 24 Issue: 4 Pages: 532-541
- DOI
  10.1021/tx100410y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390038
[Presentation] 急性肝再生過程におけるON/OFF制御へのNrf2の関与2021
- Author(s)
  高須伸二，松本佳奈，石井雄二，小川久美子，梅村隆志
- Organizer
  第37回日本毒性病理学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06042
[Presentation] Molecular pathological differences between nodular regenerative hepatocellular hyperplasias and hepatocellular adenoma induced by long term exposure of piperonyl butoxid to mice.2017
- Author(s)
  Takasu S, Yokoo Y, Ishii Y, Kijima A, Ogawa K, Umemura T
- Organizer
  15th European Congress of Toxicologic Pathology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07732
[Presentation] Piperonyl butoxide誘発マウス結節性再生性肝細胞過形成の腫瘍性病変との分子病理学的差異2017
- Author(s)
  高須伸二，横尾諭，木島綾希，石井雄二，小川久美子，梅村隆志
- Organizer
  第33回日本毒性病理学会学術集会
- Place of Presentation
  ビッグ・アイ
- Year and Date
  2017-01-26
- Data Source
  KAKENHI-PROJECT-15K07732
[Presentation] 急性的な増殖刺激により惹起される肝細胞再生過程におけるNrf2の関与2017
- Author(s)
  高須伸二，石井雄二，木島綾希，小川久美子，梅村隆志
- Organizer
  第44回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-15K07732

1. INOUE Tohru (50100110)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. TAKAGI Atsuya (00179417)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. HIRABAYASHI Yoko (30291115)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. FUKUHARA Kiyoshi (70189968)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. SYODA Takuji (60435708)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. OKUDA Haruhiro (30160807)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 横田崇 (50134622)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 高須伸二 (00597891)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
9. OHNO Akiko (70356236)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. HIROSE Akihiko (90228833)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SASAKI Hideki (50106316)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SAGA Yumiko (50221271)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. NISHIKAWA Akiyoshi (30164544)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 藤本成明 (40243612)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 能美健彦 (30150890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 佐井君江 (20195960)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KANKI Keita

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Umemura Takashi 梅村 隆志

UMEMURA Takashi 梅村 隆志

UMEMURA takashi 梅村 隆史

梅村 隆志 ウメムラ タカシ

Research Projects

Research Products

Co-Researchers

Nrf2/Notch signal pathways contributing to ON/OFF regulation in sustained livre regenerationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Possible involvement of Nrf2 in breakdown of liver regeneration programPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on synthetic antioxidants for prevention of oxidative stress-related diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Design and Synthesis of Antioxidant for a New Type of Chemopreventive Agents

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on molecular mechanisms underlying endogenous carcinogenesis using transgenic reporter genes as internal probes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

薬剤評価モデルとしてのヒト型造血因子受容体遺伝子導入マウスとその造血幹細胞動態制御

Principal Investigator

Project Period (FY)

Research Category

Research Institution

遺伝子改変動物の造血幹細胞動態制御を指標としたサイトカイン系薬剤評価モデルの開発

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Signal transduction mediated by hematopoietic factors and TGF-β in p53-deficient mice

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Construction of mouse embryonic stem cells for the detection of gene mutation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Molecular Pathological Differences in Global Gene Expression between Two Sustained Proliferative Lesions, Nodular Regenerative Hepatocellular Hyperplasia and Hepatocellular Adenoma, in Mice.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Determination of Lusidin-specific DNA adducts by liquid chromatography with tandem mass spectrometry in the livers and kidneys of rats given Lucidin-3-O-primeveroside2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Detection and quantification of specific-DNA adducts by LC-MS/MS in the livers of rats given estragole at the carcinogenic dose2011

Author(s)

Journal Title

DOI

Data Source

[Presentation] 急性肝再生過程におけるON/OFF制御へのNrf2の関与2021

Author(s)

Organizer

Data Source

[Presentation] Molecular pathological differences between nodular regenerative hepatocellular hyperplasias and hepatocellular adenoma induced by long term exposure of piperonyl butoxid to mice.2017

Author(s)

Umemura Takashi 梅村隆志

UMEMURA Takashi 梅村隆志

UMEMURA takashi 梅村隆史

梅村隆志ウメムラタカシ