Yoshihiro Ohmori 大森喜弘

… Alternative Names

大森喜弘オオモリヨシヒロ

OHMORI Yshihiro 大森喜弘

大森善弘オオモリヨシヒロ

OHMORI Yoshihiro 大森喜弘

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Researcher Number	50194311
Other IDs	https://orcid.org/0000-0002-6069-357X
Affiliation (Current)	2025: 明海大学, 歯学部, 教授
Affiliation (based on the past Project Information) *help	2022: 明海大学, 歯学部, 名誉教授 2018 – 2022: 明海大学, 歯学部, 教授 2005 – 2016: 明海大学, 歯学部, 教授 2001 – 2003: 明海大学, 歯学部, 教授 1990: 明海大学, 歯学部, 講師
Review Section/Research Field	Principal Investigator Functional basic dentistry / Basic Section 57020:Oral pathobiological science-related / Morphological basic dentistry / Pathobiological dentistry/Dental radiology Except Principal Investigator Pathobiological dentistry/Dental radiology / Basic Section 57060:Surgical dentistry-related / Surgical dentistry / Morphological basic dentistry / Morphological basic dentistry
Keywords	Principal Investigator NF-κB / ケモカイン / STAT1 / 遺伝子発現 / インターフェロン / Interferon / LPS / STAT / Chemokine / CXCL10 … More / CXCL9 / 転写制御 / マクロファージ / シグナル伝達 / 口腔癌 / 腫瘍免疫 / ヒストン脱アセチル化酵素阻害剤 / ヒストンメチル期転移酵素阻害剤 / HDAC阻害剤 / メチル化阻害剤 / 細胞増殖 / エピゲノム / メチル化 / 口腔癌細胞 / インターフェロン耐性 / MAP kinase / Phosphorylation / Transcription factor / interferon / MAPキナーゼ / リン酸化 / 転写因子 / Molecular Biology / Coactivator / Cytokine / Transcriptional regulation / Gene expression / 転写共役因子 / IP-10 / MIG / Interferon-γ / 癌細胞 / 分子生物学 / コアクチベーター / サイトカイン / Mediator / NF-kB / CDK8 / メディエーター複合体 / 低酸素 / IL-13 / 抗炎症 / 口腔扁平上皮癌 / CD163 / 免疫組織 / IL-4 / STAT6 / Il-4 / 腫瘍 / M2マクロファージ / CXCL1 / リポ多糖 / 炎症性遺伝子 / 遺伝子制御 … More Except Principal Investigator アポトーシス / 口腔癌 / GRIM-19 / STAT3 / 口腔扁平上皮癌 / p53 / サイトカイン / 扁平上皮癌 / GRIM19 / IFN / IFN誘導性ケモカイン / T細胞 / IFN誘導生ケモカイン / CXCL10 / DPP4 / 脂肪酸合成酵素 / オートファジー細胞死 / E-FABP / Resveratrol / 細胞死 / SREBP / 脂肪酸合成酵素（FAS） / Gene expression / Periodontal disease / Periodonal pathogen / Gingival fibroblasts / Cytokines / Inflammation / 遺伝子発現 / 歯周疾患 / 歯周病病原性細菌 / 歯肉線維芽細胞 / 炎症 / M２マクロファージ / M1マクロファージ / 腫瘍 / マクロファージ / 腫瘍関連マクロファージ / rapamycin / Lactacystin / オートファジー / ＩＦＮ / NF-κB / TNF-α / IL-23 / 口腔癌細胞 / 抗九九癌細胞 / インターフェロン / 炎症学 / 生理活性 / シグナル伝達 / 発現制御 / 感染症 / JAK / STAT / MTM / 細胞膜透過性 / IRAK-M / SOCS / 蛋白質療法 / TLR / 口腔細菌学 Less

Inactivation of IFN-induced chemokines by DPP4 and its clinical significance in oral cancer
- Principal Investigator
  
  MORI Kazumasa
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Meikai University
Elucidation of the mechanisms of interferon resistance in oral cancer and the efficacy of combined immuno-epigenomic therapyPrincipal Investigator
- Principal Investigator
  
  Yoshihiro Ohmori
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Meikai University
Analysis of proliferation and progression mechanisms in oral cancer which targeted fatty acid synthesis
- Principal Investigator
  
  Fukuda Masakatsu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Meikai University
The mechanism of development of tumor-associated macrophage in oral squamous cell carcinoma
- Principal Investigator
  
  HIROI Miki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Meikai University
The role of the Mediator complexes in transcriptional regulation of the chemokine genesPrincipal Investigator
- Principal Investigator
  
  Ohmori Yoshihiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Meikai University
Functional Analysis of Apoptosis Regulatory Factor GRIM19 in Oral Carcinoma Cells
- Principal Investigator
  
  Mori Kazumasa
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Meikai University
Clarification of proliferation and deveropment mechanism as the targetting cytokine in oral cancer
- Principal Investigator
  
  SAKASHITA Hideaki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Meikai University
Analysis of regulatory mechanisms of expression of apoptosis inducing factor GRIM-19
- Principal Investigator
  
  MORI Kazumasa
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Meikai University
Regulatory mechanisms of gene expression in anti-inflammatory M2 macrophagesPrincipal Investigator
- Principal Investigator
  
  OHMORI Yoshihiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Meikai University
A fundamental study about development of the protein therapy using suppressors of TLR signaling
- Principal Investigator
  
  HANAZAWA Shigemasa
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Nihon University
Mechanism of Transcriptional Repression of Inflammatory Gene Expression by STAT1Principal Investigator
- Principal Investigator
  
  OHMORI Yoshihiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Meikai University
Functional Analysis of Apoptosis Regulatory Factor GRIM19 in Oral Carcinoma Cells
- Principal Investigator
  
  MORI Kazumasa
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Meikai University
Role of p38 MAP Kinase in the Regulation of Inflammatory Gene ExpressionPrincipal Investigator
- Principal Investigator
  
  OHMORI Yoshihiro
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Meikai University
Molecular Mechanisms of Inflammatory Gene Expression by Thanscriptional factors STAT1 and NF-κBPrincipal Investigator
- Principal Investigator
  
  OHMORI Yoshihiro
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Meikai University
Regulation of Cytokines for Gene Expression and Function of Gingival Fibroblasts
- Principal Investigator
  
  HANAZAWA Shigemasa
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Miekai University School of Dentistry

All 2022 2021 2020 2015 2012 2011 2008 2006 2005 Other

All Journal Article Presentation Book

[Book] The Role of Tumor Microenvironment in Oral Cancer2012
- Author(s)
  Masakatsu Fukuda, Yoshihiro Ohmori and Hideaki Sakashita
- Publisher
  IN Tumor Microenvironment and Myelomonocytic Cells
- Data Source
  KAKENHI-PROJECT-23592974
[Book] The Role of Tumor Microenvironment in Oral Cancer. IN Tumor Microenvironment and Myelomonocytic Cells, (S.K. Biswas, ed.)2012
- Author(s)
  Masakatsu Fukuda, Yoshihiro Ohmori and Hideaki Sakashita
- Publisher
  InTech, Rijeka, Croatia
- Data Source
  KAKENHI-PROJECT-23592974
[Journal Article] Enhanced Cytotoxic Effects in Human Oral Squamous Cell Carcinoma Cells Treated with Combined Methyltransferase Inhibitors and Histone Deacetylase Inhibitors2022
- Author(s)
  Ryosuke Ushio, Miki Hiroi, Ari Matsumoto, Kazumasa Mori, Nobuharu Yamamoto, Yoshihiro Ohmori
- Journal Title
  
  Biomedicines
  
  Volume: 10 Issue: 4 Pages: 763-763
- DOI
  10.3390/biomedicines10040763
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10076, KAKENHI-PROJECT-20K10102
[Journal Article] Tumor-associated macrophages in oral premalignant lesions coexpress CD163 and STAT1 in a Th1-dominated microenvironment.2015
- Author(s)
  Kazumasa Mori, Shigeki Haragchi, Miki Hiroi, Yoshihiro Ohmori
- Journal Title
  
  BMC Cancer
  
  Volume: 15 Issue: 1
- DOI
  10.1186/s12885-015-1587-0
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25462929
[Journal Article] Infiltration of M2 tumor-associated macrophages in oral squamous cell carcinoma correlates with tumor malignancy2011
- Author(s)
  K. Mori, M. Hiroi, J. Shimada and Y. Ohmori
- Journal Title
  
  Cancers
  
  Volume: 3 Issue: 4 Pages: 3726-3739
- DOI
  10.3390/cancers3043726
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592371, KAKENHI-PROJECT-22592244
[Journal Article] Sulindac, a Nonsteroidal Anti-inflammatory Drug, Selectively Inhibits Interferon-r-induced Expression of the Chemokine CXCL9 Gene in Mouse Macrophages2006
- Author(s)
  Sakaeda Y, Hiroi M, Shimojima T, Iguchi M, Kanegae H, Ohmori Y
- Journal Title
  
  Biochem Biophys Res Commun 350
  
  Pages: 339-344
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591949
[Journal Article] Product ion of chemokine CXCL1/KC by okadaic acid through the nuclear factor-kappa B patyway.2006
- Author(s)
  Feng, G., Ohmori, Y., Chang, P-L
- Journal Title
  
  Carcinogenesis 27
  
  Pages: 43-52
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591949
[Journal Article] Transcriptional synergism between NF-KB and STAT1.2005
- Author(s)
  Hiroi, M., Ohmori, Y
- Journal Title
  
  J. Oral Biosciences 47
  
  Pages: 230-242
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591949
[Presentation] IFN誘導性ケモカインCXCL9、CXCL10、CXCL11のマウス扁平上皮癌細胞に対する抗腫瘍作用の違い2022
- Author(s)
  松本安吏, 森一将, 廣井美紀, 嶋田淳, 山本信治, 大森喜弘
- Organizer
  第76回 NPO法人日本口腔科学会学術集会
- Data Source
  KAKENHI-PROJECT-20K10102
[Presentation] 口腔癌におけるMyeloid-derived suppressor cellとケモカインの影響についての検討2022
- Author(s)
  森　一将　松本安吏　廣井美紀　山本信治　大森喜弘
- Organizer
  第67回公益社団法人日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-20K10102
[Presentation] 口腔癌における腫瘍関連マクロファージの分化誘導に関わる浸潤T細胞の検討2021
- Author(s)
  森　一将　松本安吏　廣井美紀　山本信治　大森喜弘
- Organizer
  日本口腔外科学会
- Data Source
  KAKENHI-PROJECT-20K10102
[Presentation] 口腔扁平上皮癌細胞に対するDNAメチル化転移酵素阻害剤とヒストン脱アセチル化酵素阻害剤の併用処理による細胞傷害作用2021
- Author(s)
  牛尾亮介、廣井美紀、松本安吏、森　一将、大森喜弘
- Organizer
  第63回歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-19K10076
[Presentation] インターフェロン誘導性ケモカインCXCL9, CXCL10, CXCL11のマウス扁平上皮癌細胞に対する抗腫瘍作用の違い2021
- Author(s)
  松本安吏、森　一将、廣井美紀、大森喜弘
- Organizer
  第63回歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-19K10076
[Presentation] Differential antitumor effects of IFN-inducible chemokines CXCL9, CXCL10 and CXCL11 on mouse squamous cell carcinoma2021
- Author(s)
  Ari MATSUMOTO, Kazumasa MORI, Miki HIROI, Yoshihiro OHMORI
- Organizer
  Japanese Association for Oral Biology
- Data Source
  KAKENHI-PROJECT-20K10102
[Presentation] Investigation of chemokines involved in the infiltration of myeloid-derived suppressor cells (MDSCs) in the mouse tongue cancer model2021
- Author(s)
  Kazumasa MORI, Miki HIROI, Ari MATSUMOTO, Ryousuke USHIO, Yoshihiro OHMORI
- Organizer
  Japanese Association for Oral Biology
- Data Source
  KAKENHI-PROJECT-20K10102
[Presentation] マウス舌癌モデルにおけるMyeloid-derived suppressor cells (MDSCs)の浸潤に関わるケモカインの検討2021
- Author(s)
  森　一将、廣井美紀、松本安吏、牛尾亮介、大森喜弘
- Organizer
  第63回歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-19K10076
[Presentation] メチル化阻害剤によるIFN耐性ヒト口腔扁平上皮癌細胞に対する細胞増殖抑制作用2020
- Author(s)
  牛尾亮介、廣井美紀、松本安吏、森一将、嶋田淳、山本信治、大森喜弘
- Organizer
  第65回口腔外科学会　総会
- Data Source
  KAKENHI-PROJECT-19K10076
[Presentation] メチル化阻害剤による口腔扁平上皮癌細胞の増殖抑制作用2020
- Author(s)
  牛尾亮介、廣井美紀、嶋田　淳、山本信治、大森喜弘
- Organizer
  第62回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-19K10076
[Presentation] 口腔前癌病変におけるCD163+腫瘍関連マクロファージの分化誘導への浸潤ヘルパー1型T細胞の関与2015
- Author(s)
  森一将、廣井美紀、嶋田淳、大森喜弘
- Organizer
  第57回歯科基礎医学会学術大会
- Place of Presentation
  朱鷺メッセ（新潟県新潟市）
- Year and Date
  2015-09-13
- Data Source
  KAKENHI-PROJECT-26462855
[Presentation] 抗炎症性M2マクロファージにおけるArg-1遺伝子発現制御機構2011
- Author(s)
  廣井美紀、大森喜弘
- Organizer
  第53回日本歯科基礎医学会総会
- Place of Presentation
  岐阜、長良川国際会議場
- Year and Date
  2011-10-02
- Data Source
  KAKENHI-PROJECT-21592371
[Presentation] 抗炎症性M2マクロファージにおけるArg-1遺伝子発現制御機構2011
- Author(s)
  廣井美紀, 大森喜弘
- Organizer
  歯科基礎医学会
- Place of Presentation
  岐阜
- Year and Date
  2011-10-02
- Data Source
  KAKENHI-PROJECT-21592371
[Presentation] 新規アポトーシス制御因子GRIM-19の口腔癌細胞における発現2008
- Author(s)
  森一将、廣井美紀、嶋田淳、大森喜弘
- Organizer
  第53回日本口腔外科学会総会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-19592178
[Presentation] 新規アポトーシス制御因子GRIM-19の口腔癌細胞における機能解析2008
- Author(s)
  森一将、廣井美紀、嶋田淳、大森喜弘
- Organizer
  第50回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19592178
[Presentation] マウスマクロファージにおけるインターフェロンγによる炎症性ケモカイン遺伝子の発現抑制機構2008
- Author(s)
  廣井美紀、大森喜弘
- Organizer
  第50回歯科基礎医学会総会
- Place of Presentation
  東京
- Year and Date
  2008-09-25
- Data Source
  KAKENHI-PROJECT-19592158
[Presentation] ケモカイン遺伝子のメディエーター複合体による転写制御
- Author(s)
  廣井美紀、大森喜弘
- Organizer
  第56回歯科基礎医学会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25462928

1. MORI Kazumasa (80372902)

# of Collaborated Projects: 5 results

# of Collaborated Products: 9 results
2. HIROI Miki (30419717)

# of Collaborated Projects: 5 results

# of Collaborated Products: 16 results
3. SEKINE Keisuke (00323569)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. HANAZAWA Shigemasa (60060258)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. SAKASHITA Hideaki (10178551)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. FUKUDA Masakatsu (10311614)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
7. MASUHIRO Yoshikazu (00336083)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. AMANO Shigeru (90167958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 小貫裕之 (50598258)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Yoshihiro Ohmori 大森 喜弘

大森 喜弘 オオモリ ヨシヒロ

OHMORI Yshihiro 大森 喜弘

大森 善弘 オオモリ ヨシヒロ

OHMORI Yoshihiro 大森 喜弘

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Elucidation of the mechanisms of interferon resistance in oral cancer and the efficacy of combined immuno-epigenomic therapyPrincipal Investigator

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The role of the Mediator complexes in transcriptional regulation of the chemokine genesPrincipal Investigator

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Regulatory mechanisms of gene expression in anti-inflammatory M2 macrophagesPrincipal Investigator

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Mechanism of Transcriptional Repression of Inflammatory Gene Expression by STAT1Principal Investigator

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Role of p38 MAP Kinase in the Regulation of Inflammatory Gene ExpressionPrincipal Investigator

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Molecular Mechanisms of Inflammatory Gene Expression by Thanscriptional factors STAT1 and NF-κBPrincipal Investigator

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Yoshihiro Ohmori 大森喜弘

大森喜弘オオモリヨシヒロ

OHMORI Yshihiro 大森喜弘

大森善弘オオモリヨシヒロ

OHMORI Yoshihiro 大森喜弘