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Hatada Izuho  畑田 出穂

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HATADA Izuho  畑田 出穂

畑田 出穂  ハタダ イズホ

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Researcher Number 50212147
Other IDs
Affiliation (Current) 2025: 群馬大学, 生体調節研究所, 教授
Affiliation (based on the past Project Information) *help 2011 – 2024: 群馬大学, 生体調節研究所, 教授
2007 – 2009: Gunma University, 生体調節研究所, 准教授
2004 – 2006: Gunma University, Laboratory of Genome Science, Biosignal Genome Resource Center, Department of Molecular and Cellular Biology, Associate Professor, 生体調節研究所, 助教授
1999 – 2003: 群馬大学, 遺伝子実験施設, 助教授
1996: 国立循環器病センター研究所, バイオサイエンス部, 室員
1994: 国立循環器病センター研究所, バイオサイエンス部, 室員
Review Section/Research Field
Principal Investigator
Biological Sciences / Molecular biology / Basic Section 56040:Obstetrics and gynecology-related / Basic Section 48040:Medical biochemistry-related / Medical genome science / System genome science / Developmental biology / Laboratory animal science / epigenetics
Except Principal Investigator
Basic Section 59040:Nutrition science and health science-related … More / Basic Section 55020:Digestive surgery-related / Genome biology / Animal production science / Molecular biology / Applied animal science / Hygiene and public health / epigenetics / Biological Sciences Less
Keywords
Principal Investigator
メチル化 / エピジェネティクス / インプリンティング / マイクロアレイ / 癌抑制遺伝子 / エピジェネティク / エピゲノム編集 / ゲノム編集 / エピゲノム / DNAメチル化 … More / miRNA / 卵子 / 癌 / 卵母細胞 / 癌遺伝子 / ゲノム / 子宮体癌 / 偽遺伝子 / Imprinting / Methylation / ヒストン / oocyte / germ cell / nuclear transplantation / methylation / imprinting / 生殖細胞 / 核移植 / DNAメチル / 分化 / エビジェネティクス / ゲノムワイド / 原始生殖細胞 / 原始卵胞 / 卵胞 / ゲノムインプリンティング / インシュリン / 糖尿病関連遺伝子 / DNAチップ / Microarray / トランスジェニックマウス / U2af1-rs1 / メチレーション / X inactivation / RNA / Xist / 小児癌 / Wilms腫瘍 / p57KIP2 / サイクリン依存性キナーゼインヒビター / Beckwith-Wiedemann症候群 / ゲノミックインプリンティング / ゲノムスキャンニング / 遺伝的刷り込み … More
Except Principal Investigator
エピゲノム / エピジェネティクス / 肥満 / ゲノムインプリンティング / ES細胞 / DNAメチル化 / 核移植 / 卵母細胞 / エピトランスクリプトーム / 視床下部 / 多階層オミクス解析 / 抗がん剤感受性 / O-GlcNAc / KRAS / 新規治療標的 / O-GlcNAc修飾 / 膵がん / インプリンティング / 父性遺伝 / CRISPR/Cas / FACS / 半数体 / リボソーム / ミトコンドリア / 翻訳停滞解消因子 / Development / In vitro culture / Genomic imprinting / Nuclear transfer / Oocytes / 体外培養 / 発生 / 対外培養 / miiRNA / 継世代影響 / 発がん / 胎児期曝露 / エピ変異 / miRNA / F2影響 / 肝腫瘍 / 妊娠期曝露 / 無機ヒ素 / 再生医療 / 腫瘍 / 単為発生胚 / インプリント遺伝子 / 移植医療 / テラトーマ / 腫瘍形成 / ゲノムインプリント / 単為発生 / 生殖細胞 / 性分化 / 卵子形成 / 胚発生 / ゲノミックインプリンティング / 生殖細胞分化 Less
  • Research Projects

    (32 results)
  • Research Products

    (109 results)
  • Co-Researchers

    (26 People)
  •  Innovative Combination Immunotherapy Targets Vulnerability of KMT2 Mutant Uterine CancerPrincipal Investigator

    • Principal Investigator
      畑田 出穂
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Gunma University
  •  膵がん治療におけるO-GlcNAc分解酵素OGAの重要性とその分子機構の解明

    • Principal Investigator
      川端 麗香
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Gunma University
  •  The role of epigenome and epitranscriptome in the development of obesity

    • Principal Investigator
      河野 大輔
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Gunma University
  •  Histone methyltransferase KMT2 mutation-induced epigenomic abnormalities and endometrial cancer development and progressionPrincipal Investigator

    • Principal Investigator
      Hatada Izuho
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      Gunma University
  •  A new therapeutic strategy for autoimmune diseases through epigenome editingPrincipal Investigator

    • Principal Investigator
      Hatada Izuho
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical genome science
    • Research Institution
      Gunma University
  •  Analysis of the paternal transmission of obesity.

    • Principal Investigator
      Morita Sumiyo
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Genome biology
    • Research Institution
      Gunma University
  •  Functional analysis of stalled-ribosome rescue factors in mitochondria

    • Principal Investigator
      Nameki Nobukazu
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Molecular biology
    • Research Institution
      Gunma University
  •  Establishment of simple culture system for haploid embryonic stem cells

    • Principal Investigator
      Horii Takuro
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Animal production science
    • Research Institution
      Gunma University
  •  Is pseudogene fake?Principal Investigator

    • Principal Investigator
      Hatada Izuho
    • Project Period (FY)
      2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      System genome science
    • Research Institution
      Gunma University
  •  Studies on epimutations that are involved in multigenerational effects of environmental chemicals in mice

    • Principal Investigator
      Nohara Keiko
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hygiene and public health
    • Research Institution
      National Institute for Environmental Studies
  •  Establishment of pluripotent stem cells with low tumorigenesity by use of genomic imprinting

    • Principal Investigator
      HORII Takuro
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      epigenetics
    • Research Institution
      Gunma University
  •  Why methylation and demethylation occur simultaneously in cancersPrincipal Investigator

    • Principal Investigator
      HATADA Izuho
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      epigenetics
    • Research Institution
      Gunma University
  •  マイクロアレイによる肺癌のメチル化網羅的解析と診断・治療のターゲットの検討Principal Investigator

    • Principal Investigator
      畑田 出穂
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Gunma University
  •  網羅的エピゲノムデータのモチーフ解析によるmiRNAの転写制御への関与の検討Principal Investigator

    • Principal Investigator
      畑田 出穂
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Gunma University
  •  プロモーターメチル化アレイによる肺癌のゲノムワイドなエピジェネティク解析Principal Investigator

    • Principal Investigator
      畑田 出穂
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Gunma University
  •  脱メチル化ターゲット配列データベースの作成と共通モチーフの解明Principal Investigator

    • Principal Investigator
      畑田 出穂
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Gunma University
  •  卵胞培養系を用いたハイスループット遺伝子機能解析Principal Investigator

    • Principal Investigator
      畑田 出穂
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Gunma University
  •  成長期卵母細胞におけるSETドメインを持つ遺伝子の網羅的解析Principal Investigator

    • Principal Investigator
      畑田 出穂
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Gunma University
  •  DNAチップを用いたハイスループットなメチル化検出システムPrincipal Investigator

    • Principal Investigator
      畑田 出穂
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Gunma University
  •  雄性生殖細胞に卵子発生プログラムを書き込むことは可能か?

    • Principal Investigator
      OBATA Yayoi
    • Project Period (FY)
      2003 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo University of Agriculture
  •  Is methylation of histone required for imprinting?Principal Investigator

    • Principal Investigator
      HATADA Izuho
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Developmental biology
    • Research Institution
      Gunma University
  •  Control of epigenetic modification for oocytes genome

    • Principal Investigator
      KONO Tomohiro
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied animal science
    • Research Institution
      TOKYO UNIVERSITY OF AGRICULTURE
  •  インプリンティングを指標とした糖尿病関連遺伝子の検索Principal Investigator

    • Principal Investigator
      畑田 出穂
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Gunma University
  •  Development of method to make oocyte from male germ cellsPrincipal Investigator

    • Principal Investigator
      HATADA Izuho
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      Gunma University
  •  Microarrayを利用したDNAメチル化のゲノムスキャンニングPrincipal Investigator

    • Principal Investigator
      畑田 出穂
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Gunma University
  •  インプリンティンブを指標とした糖尿病関連遺伝子の検索Principal Investigator

    • Principal Investigator
      畑田 出穂
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Gunma University
  •  インプリンティングを指標とした癌関連遺伝子の組織的単離法Principal Investigator

    • Principal Investigator
      畑田 出穂
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Gunma University
  •  インプリンティングを利用した癌抑制遺伝子の組織的単離法Principal Investigator

    • Principal Investigator
      畑田 出穂
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Gunma University
  •  X染色体不活性化をおこなう機能的RNA-Xistの標的の探索Principal Investigator

    • Principal Investigator
      畑田 出穂
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Gunma University
  •  インプリンティングの分子機構の解明Principal Investigator

    • Principal Investigator
      畑田 出穂
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Molecular biology
    • Research Institution
      Gunma University
  •  サイクリン依存性キナーゼインヒビターp57KIP2の小児癌への関与の検討Principal Investigator

    • Principal Investigator
      畑田 出穂
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      National Cardiovascular Center Research Institute
  •  遺伝的刷り込み現象を示す遺伝子SP2のトランスジェニックマウスによる解析Principal Investigator

    • Principal Investigator
      畑田 出穂
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Molecular biology
    • Research Institution
      National Cardiovascular Center Research Institute

All 2022 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2002 Other

All Journal Article Presentation Book Patent Other

  • [Book] Editing of DNA Methylation Using dCas9-Peptide Repeat and scFv-TET1 Catalytic Domain Fusions. Morita S, Horii T, Hatada I. Methods Mol Biol.2018

    • Author(s)
      Morita S, Horii T, Hatada I.
    • Total Pages
      288
    • Publisher
      Springer Nature
    • ISBN
      9781493977734
    • Data Source
      KAKENHI-PROJECT-17H03613
  • [Book] All About ゲノム編集2016

    • Author(s)
      畑田出穂、森田純代、堀居拓郎
    • Total Pages
      240
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-15K07687
  • [Book] Epigenetic Instability in Embryonic Stem Cells2013

    • Author(s)
      T Horii and I Hatada
    • Total Pages
      16
    • Publisher
      INTECH
    • Data Source
      KAKENHI-PROJECT-24613002
  • [Book] The epigenomics of cancer. In Omics perspective of cancer Cho, William C.S.(Ed.)2010

    • Author(s)
      Hatada I
    • Total Pages
      269
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-20016002
  • [Book] The epigenomics of cancer. In Omics perspective of cancer Cho, William C.S.(Ed.)2010

    • Author(s)
      Hatada I
    • Total Pages
      269
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-20012009
  • [Book] Genomic-wide DNA Methylation Profiling Methods From RLGS to MIAMI In Progress in DNA Methylation Research2008

    • Author(s)
      Hatada I
    • Total Pages
      256
    • Publisher
      Nova Publishes
    • Data Source
      KAKENHI-PROJECT-20016002
  • [Book] Genomic-wide DNA Methylation Profiling. Methods-From RLGS to MIAMI. In Progress in DNA Methylation Research2008

    • Author(s)
      Hatada I
    • Total Pages
      256
    • Publisher
      Nova Publishes
    • Data Source
      KAKENHI-PROJECT-20012009
  • [Book] Genomic-wide DNA Methylation Profiling Methods-From RLGS to Miami. In Progress in DNA Methylation Research2007

    • Author(s)
      Hatada I
    • Publisher
      Nova Publishers (in press)
    • Data Source
      KAKENHI-PROJECT-18016003
  • [Book] Genomic-wide DNA Methylation Profiling Methods- From RLGS to Miami. In Progress in DNA Methylation Research2007

    • Author(s)
      Hatada I
    • Publisher
      Nova Publishers (in press)
    • Data Source
      KAKENHI-PROJECT-18012010
  • [Journal Article] Multiplexed genome editing by in vivo electroporation of Cas9 ribonucleoproteins effectively induces endometrial carcinoma in mice2022

    • Author(s)
      Kobayashi Ryosuke、Kawabata‐Iwakawa Reika、Sugiyama Makoto、Oyama Tetsunari、Ohtsuka Masato、Horii Takuro、Morita Sumiyo、Nishiyama Masahiko、Hatada Izuho
    • Journal Title

      International Journal of Cancer

      Volume: 152 Issue: 11 Pages: 2331-2337

    • DOI

      10.1002/ijc.34342

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K15026, KAKENHI-PROJECT-20H03431, KAKENHI-PROJECT-20J01824
  • [Journal Article] Synergistic Upregulation of Target Genes by TET1 and VP64 in the dCas9-SunTag Platform.2020

    • Author(s)
      Morita S, Horii T, Kimura M, Hatada I.
    • Journal Title

      Int J Mol Sci.

      Volume: 21 Issue: 5 Pages: 1574-1574

    • DOI

      10.3390/ijms21051574

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K06607, KAKENHI-PROJECT-17H03613, KAKENHI-PROJECT-19H03143
  • [Journal Article] Successful generation of epigenetic disease model mice by targeted demethylation of the epigenome.2020

    • Author(s)
      Horii T, Morita S, Hino S, Kimura M, Hino Y, Kogo H, Nakao M & Hatada I
    • Journal Title

      Genome Biology

      Volume: 21(1) Issue: 1 Pages: 77-77

    • DOI

      10.1186/s13059-020-01991-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03613, KAKENHI-PROJECT-19H03143, KAKENHI-PROJECT-18K19479, KAKENHI-PROJECT-19K06607, KAKENHI-PROJECT-19K07262, KAKENHI-PROJECT-18H02618, KAKENHI-PROJECT-20H04108
  • [Journal Article] Targeted DNA demethylation of the Fgf21 promoter by CRISPR/dCas9-mediated epigenome editing.2020

    • Author(s)
      Hanzawa N, Hashimoto K, Yuan X, Kawahori K, Tsujimoto K, Hamaguchi M, Tanaka T, Nagaoka Y, Nishina H, Morita S, Hatada I, Yamada T, Ogawa Y.
    • Journal Title

      Sci Rep.

      Volume: 10 Issue: 1 Pages: 5181-5181

    • DOI

      10.1038/s41598-020-62035-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K06607, KAKENHI-PROJECT-19K18000, KAKENHI-PROJECT-17H03613, KAKENHI-PROJECT-18H02859, KAKENHI-PROJECT-17K01840, KAKENHI-PROJECT-19K09018, KAKENHI-PROJECT-20H03381
  • [Journal Article] Differentiation Therapy by Epigenetic Reconditioning Exerts Antitumor Effects on Liver Cancer Cells2018

    • Author(s)
      Gailhouste Luc、Liew Lee Chuen、Yasukawa Ken、Hatada Izuho、Tanaka Yasuhito、Nakagama Hitoshi、Ochiya Takahiro
    • Journal Title

      Molecular Therapy

      Volume: 26 Issue: 7 Pages: 1840-1854

    • DOI

      10.1016/j.ymthe.2018.04.018

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03613
  • [Journal Article] Epigenetic reprogramming using 5-azacytidine promotes an anti-cancer response in pancreatic adenocarcinoma cells.2018

    • Author(s)
      Gailhouste L, Liew LC, Hatada I, Nakagama H, Ochiya T.
    • Journal Title

      Cell Death Dis.

      Volume: 9 Issue: 5 Pages: 468-468

    • DOI

      10.1038/s41419-018-0487-z

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03613
  • [Journal Article] Editing of DNA Methylation Using dCas9-Peptide Repeat and scFv-TET1 Catalytic Domain Fusions2018

    • Author(s)
      Morita Sumiyo、Horii Takuro、Hatada Izuho
    • Journal Title

      Methods Mol Biol.

      Volume: 1767 Pages: 419-428

    • DOI

      10.1007/978-1-4939-7774-1_23

    • ISBN
      9781493977734, 9781493977741
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03613, KAKENHI-PROJECT-16K07194
  • [Journal Article] Genome Engineering Using Haploid Embryonic Stem Cells.2017

    • Author(s)
      Horii T, Hatada I.
    • Journal Title

      Prog Mol Biol Transl Sci.

      Volume: 152 Pages: 83-94

    • DOI

      10.1016/bs.pmbts.2017.09.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-17H05613, KAKENHI-PROJECT-15K07687
  • [Journal Article] Genome Editing of Mouse by Cytoplasmic Injection.2017

    • Author(s)
      Horii T, Hatada I.
    • Journal Title

      Methods Mol Biol.

      Volume: 1630 Pages: 55-66

    • DOI

      10.1007/978-1-4939-7128-2_5

    • ISBN
      9781493971275, 9781493971282
    • Data Source
      KAKENHI-PROJECT-15K07687
  • [Journal Article] Efficient generation of conditional knockout mice via sequential introduction of lox sites.2017

    • Author(s)
      Horii T, Morita S, Kimura M, Terawaki N, Shibutani M, Hatada I.
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 7891-7891

    • DOI

      10.1038/s41598-017-08496-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-17H05613, KAKENHI-PROJECT-15K07687
  • [Journal Article] 肥満のエピジェネティクスとその世代間継承2016

    • Author(s)
      畑田出穂、森田純代
    • Journal Title

      実験医学増刊, エピゲノム研究 修飾の全体像の理解から先制・個別化医療へ, 羊土社

      Volume: 34 Pages: 1617-1621

    • Data Source
      KAKENHI-PROJECT-16K07194
  • [Journal Article] Targeted DNA demethylation in vivo using dCas9-peptide repeat and scFv-TET1 catalytic domain fusions.2016

    • Author(s)
      Morita S, Noguchi H, Horii T, Nakabayashi K, Kimura M, Okamura K, Sakai A, Nakashima H, Hata K, Nakashima K, Hatada I
    • Journal Title

      Nat Biotechnol.

      Volume: 34 Issue: 10 Pages: 1060-1065

    • DOI

      10.1038/nbt.3658

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460409, KAKENHI-PROJECT-15K14452, KAKENHI-PROJECT-15K07687, KAKENHI-PROJECT-16K07137
  • [Journal Article] Regulation of CpG methylation by Dnmt and Tet in pluripotent stem cells2016

    • Author(s)
      Horii T, Hatada I.
    • Journal Title

      J. Reprod. Dev.

      Volume: 62 Issue: 4 Pages: 331-335

    • DOI

      10.1262/jrd.2016-046

    • NAID

      130005406815

    • ISSN
      0916-8818, 1348-4400
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07687
  • [Journal Article] 5-hydroxymethylcytosine marks sites of DNA damage and promotes genome stability.2016

    • Author(s)
      Georgia R. Kafer, Xuan Li, Takuro Horii, Isao Suetake, Shoji Tajima, Izuho Hatada, Peter M. Carlton.
    • Journal Title

      Cell Reports

      Volume: 14 Issue: 6 Pages: 1283-1292

    • DOI

      10.1016/j.celrep.2016.01.035

    • NAID

      120005707793

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25291025, KAKENHI-PROJECT-15K07687
  • [Journal Article] Genome Editing Using Mammalian Haploid Cells2015

    • Author(s)
      Horii T, Hatada I
    • Journal Title

      International Journal of Molecular Science

      Volume: 16 Issue: 10 Pages: 23604-23614

    • DOI

      10.3390/ijms161023604

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07687
  • [Journal Article] Gene expression profiling of white adipose tissue reveals paternal transmission of proneness to obesity.2015

    • Author(s)
      Morita S, Nakabayashi K, Kawai T, Hayashi K, Horii T, Kimura M, Kamei Y, Ogawa Y, Hata K, Hatada I
    • Journal Title

      Sci. Rep.

      Volume: 6 Issue: 1 Pages: 21693-21693

    • DOI

      10.1038/srep21693

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25460409, KAKENHI-PROJECT-26560076, KAKENHI-PROJECT-15K14432, KAKENHI-PROJECT-25292076, KAKENHI-PROJECT-16H04926, KAKENHI-PROJECT-15K12669, KAKENHI-PROJECT-16K07194
  • [Journal Article] Validation of microinjection methods for generating knockout mice by CRISPR/Cas-mediated genome engineering2014

    • Author(s)
      Horii T, Arai Y, Yamazaki M, Morita S, Kimura M, Itoh M, Abe Y, Hatada I
    • Journal Title

      Sci Rep

      Volume: 4 Issue: 1 Pages: 4513-4513

    • DOI

      10.1038/srep04513

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591816, KAKENHI-PROJECT-24613002
  • [Journal Article] Generation of an ICF Syndrome Model by Efficient Genome Editing of Human Induced Pluripotent Stem Cells Using the CRISPR System2013

    • Author(s)
      Horii T, Tamura D, Morita S, Kimura M, Hatada I
    • Journal Title

      Int J Mol Sci

      Volume: 14 Pages: 19774-19781

    • Data Source
      KAKENHI-PROJECT-23616001
  • [Journal Article] Generation of an ICF Syndrome Model by Efficient Genome Editing of Human Induced Pluripotent Stem Cells Using the CRISPR System.2013

    • Author(s)
      Horii T, Tamura D, Morita S, Kimura M, , Hatada I
    • Journal Title

      Int J Mol Sci

      Volume: 14 Issue: 10 Pages: 19774-19781

    • DOI

      10.3390/ijms141019774

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23616001, KAKENHI-PROJECT-24613002
  • [Journal Article] Genome-Wide Analysis of DNA Methylation and Expression of MicroRNAs in Breast Cancer Cells.2012

    • Author(s)
      Morita S, Takahashi RU, Yamashita R, Toyoda A, Horii T, Kimura M, Fujiyama A, Nakai K, Tajima S, Matoba R, Ochiya T, Hatada I.
    • Journal Title

      Int J Mol Sci.

      Volume: 13 Pages: 8259-8272

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24613002
  • [Journal Article] The Dnmt3b Splice Variant is Specifically Expressed in In Vitro-manipulated Blastocysts and Their Derivative ES Cells2011

    • Author(s)
      Horii T, Suetake I, Yanagisawa E, Morita S, Kimura M, Nagao Y, Imai H, Tajima S, Hatada I
    • Journal Title

      J Reprod Dev

      Volume: 57 Pages: 579-585

    • NAID

      10029878177

    • Data Source
      KAKENHI-PROJECT-23616001
  • [Journal Article] The Dnmt3b splice variant is specifically expressed in in vitro-manipulated blastocysts and their derivative ES cells2011

    • Author(s)
      Horii T, Suetake I, Yanagisawa E, Kimura M, Morita S, Nagao Y, Imai H, Tajima S, Hatada I.
    • Journal Title

      J Reprod Dev

      Volume: 57 Pages: 579-585

    • NAID

      10029878177

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23616001
  • [Journal Article] Epigenetic Regulation of Adipocyte Differentiation by a Rho Guanine Nucleotide Exchange Factor, WGEF2009

    • Author(s)
      Horii T, Morita S, Kimura M, Hatada I.
    • Journal Title

      PLoS ONE 4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20012009
  • [Journal Article] Dicer is required for maintaining adult pancreas2009

    • Author(s)
      Morita S, Hara A, Kojima I, Horii T, .Kimura M, Kitamura T, Ochiya T, Nakanishi K, Matoba R, Matsubara K, Hatada I
    • Journal Title

      PLoS ONE 4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20016002
  • [Journal Article] Dicer is required for maintaining adult pancreas2009

    • Author(s)
      Morita S, Hara A, Kojima I, Horii T, Kimura M, Kitamura T, Ochiya T, Nakanishi K, Matoba R, Matsubara K, Hatada I
    • Journal Title

      PLoS ONE 4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20012009
  • [Journal Article] Epigenetic Regulation of Adipocyte Differentiation by a Rho Guanine Nucleotide Exchange Factor, WGEF.2009

    • Author(s)
      Horii T, Morita S, Kimura M, Hatada I.
    • Journal Title

      PLoS ONE 4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20016002
  • [Journal Article] Loss of Genomic Imprinting in Mouse Parthenogenetic Embryonic Stem Cells.2008

    • Author(s)
      Horii T, Kimura M, Morita S, Nagao Y & Hatada I.^*
    • Journal Title

      Stem cells 26

      Pages: 79-88

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18012010
  • [Journal Article] Mecp-2 dependent repression of an imprinted miR-184 released by depol arization.2008

    • Author(s)
      Nomura T, Kimura M, Horii T, Morita S, Soejima H, Kudo S & Hatada I^*
    • Journal Title

      Hum Mol Genet. 17

      Pages: 1192-1199

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18012010
  • [Journal Article] Geome-wide demethylation during neural differentiation of P19 embryonal carcinoma cells2008

    • Author(s)
      Hatada I,Morita S, Kimura M, Horii T, Yamashita R & Nakai K
    • Journal Title

      J Hum Genet 53

      Pages: 185-191

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20016002
  • [Journal Article] Loss of Genomic Imprinting in Mouse Parthenogenetic Embryonic Stem Cells.2008

    • Author(s)
      Horii T, Kimura M, Morita S, Nagao Y & Hatada I.^*
    • Journal Title

      Stem cells 26

      Pages: 79-88

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18016003
  • [Journal Article] A comparative analysis of the transcriptome and signal pathways in hepatic differentiation of human adipose mesenchymal stem cells2008

    • Author(s)
      Yamamoto Y, Banas A, Murata S, Ishikawa M, Lim CR, Teratani T, Hatada I, MatsubaraK, K ato T, Ochiva T
    • Journal Title

      FEBS J 275

      Pages: 1260-1273

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20016002
  • [Journal Article] Loss of Genomic Imprinting in Mouse Parthenogenetic Embryonic Stem Cells2008

    • Author(s)
      Horii T, Kimura M, Morita S, Naeao Y & Hatada I
    • Journal Title

      Stem cells 26

      Pages: 79-88

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20012009
  • [Journal Article] Mecp-2 dependent repression of an imprinted miR-184 released by depolarization2008

    • Author(s)
      Nomura T, Kimura lvi, Horii T, Morita S, Soejima H, Kudo S & Hatada I
    • Journal Title

      Hum Mol Genet 17

      Pages: 1192-1199

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20012009
  • [Journal Article] Geome-wide demethylation during neural differentiation of P19 embryonal carcinoma cells.2008

    • Author(s)
      Hatada I^*, Morita S, Kimura M, Horii T, Yamashita R & Nakai K.
    • Journal Title

      J. Hum Genet. 53

      Pages: 185-191

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18016003
  • [Journal Article] Geome-wide demethylation during neural differentiation of P19 embryonal carcinoma cells.2008

    • Author(s)
      Hatada I^*, Morita S, Kimura M, Horii T, Yamashita R & Nakai K.
    • Journal Title

      J. Hum Genet. 53

      Pages: 185-191

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18012010
  • [Journal Article] A comparative analysis of the transcriptome and signal pathways in hepatic differentiation of human adipose mesenchymal stem cells2008

    • Author(s)
      Yamamoto Y, Banas A, Murata S, Ishikawa M, Lim CR, Teratani T, Hatada I, Matsubara K, Kato T, Ochiya T.
    • Journal Title

      FEBS J 275

      Pages: 1260-1273

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20012009
  • [Journal Article] A comparative analysis of the transcriptome and signal pathways in hepatic differentiation of human adipose mesenchymal stem cells.2008

    • Author(s)
      Yamamoto Y, Banas A, Murata S, Ishikawa M, Lim CR, Teratani T, Hatada I, Matsubara K, Kato T, Ochiya T.
    • Journal Title

      FEBS J. 275

      Pages: 1260-1273

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18012010
  • [Journal Article] Astrocytespecific genes are generally demethylated in neural precursor cells prior to astrocytic differentiation2008

    • Author(s)
      Hatada I, Namihira M, Morita S, Kimura M, Horii T, Nakashima K
    • Journal Title

      PLoS ONE 3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20012009
  • [Journal Article] Geome-wide demethylation during neural differentiation of P19 embryonal carcinoma cells2008

    • Author(s)
      Hatada I, Morita S, Kimura M, Horii T, Yamashita R & Nakai K.
    • Journal Title

      J. Hum Genet 53

      Pages: 185-191

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20012009
  • [Journal Article] Loss of Genomic Imprinting in Mouse Parthenogenetic Embryonic Stem Cells2008

    • Author(s)
      Horii T, Kimura M, Morita S, Nagao Y & Hatada I
    • Journal Title

      Stem cells 26

      Pages: 79-88

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20016002
  • [Journal Article] Astrocyte-specific genes are generally demethylated in neural precursor cells prior to astrocytic differentiation2008

    • Author(s)
      Hatada I, Namihira M, Morita S, Kimura M, Horii T, Nakashima K
    • Journal Title

      PLoS ONE 3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20016002
  • [Journal Article] Mecp-2 dependent repression of an imprinted miR-184 released by depolarization2008

    • Author(s)
      Nomura T, Kimura M, Horii T, Morita S, Soejima H, Kudo S & Hatada I
    • Journal Title

      Hum Mol Genet 28

      Pages: 1192-1199

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20016002
  • [Journal Article] A comparative analysis of the transcriptome and signal pathways in hepatic differentiation of human adipose mesenchymal stem cells.2008

    • Author(s)
      Yamamoto Y, Banas A, Murata S, Ishikawa M, Lim CR, Teratani T, Hatada I, Matsubara K, Kato T, Ochiya T.
    • Journal Title

      FEBS J. 275

      Pages: 1260-1273

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18016003
  • [Journal Article] Mecp-2 dependent repression of an imprinted miR-184 released by depolarization.2008

    • Author(s)
      Nomura T, Kimura M, Horii T, Morita S, Soejima H, Kudo S & Hatada I^*
    • Journal Title

      Hum Mol Genet. 17

      Pages: 1192-1199

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18016003
  • [Journal Article] One Argonaute family member, Eif2c2 (Agog), is essential for development and appears not to be involved in DNA methylation.2007

    • Author(s)
      Morita S, Horii T, Kimura M, Goto Y, Ochiya T & Hatada I^*.
    • Journal Title

      Genomics. 89

      Pages: 687-696

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18012010
  • [Journal Article] One Argonaute family member, Eif2c2 (Ago2), is essential for development and appears not to be involved in DNA methylation2007

    • Author(s)
      Morita S, Horii T, Kimura M, Goto Y, Ochiya T, Hatada I
    • Journal Title

      Genomics (in press)

    • Data Source
      KAKENHI-PROJECT-15080201
  • [Journal Article] One Argonaute family member, Eif2c2 (Ago2), is essential for development and appears not to be involved in DNA methylation.2007

    • Author(s)
      Morita S, Horii T, Kimura M, Goto Y, Ochiya T, Hatada I
    • Journal Title

      Genomics (in press)

    • Data Source
      KAKENHI-PROJECT-18016003
  • [Journal Article] Long-Term Effects of In Vitro Growth of Mouse Oocytes on Their Maturation and Development.2007

    • Author(s)
      Obata Y, Maeda Y, Hatada I & Kono^* T.
    • Journal Title

      J Reprod Dev. 53

      Pages: 1183-1190

    • NAID

      10020172629

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18012010
  • [Journal Article] One Argonaute family member, Eif2c2 (Ago2), is essential for development and appears not to be involved in DNA methylation.2007

    • Author(s)
      Morita S, Horii T, Kimura M, Goto Y, Ochiya T, Hatada I
    • Journal Title

      Genomics (in press)

    • Data Source
      KAKENHI-PROJECT-18012010
  • [Journal Article] Long-Term Effects of In Vitro Growth of Mouse Oocytes on Their Maturation and Development.2007

    • Author(s)
      Obata Y, Maeda Y, Hatada I & Kono^* T.
    • Journal Title

      J Reprod Dev. 53

      Pages: 1183-1190

    • NAID

      10020172629

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18016003
  • [Journal Article] Long-term effects of in vitro growth of mouse oocytes on their maturation and development.2007

    • Author(s)
      Obata Y., Maeda Y., Hatada I., and Kono T.
    • Journal Title

      J Reprod Dev. 53

      Pages: 1183-1190

    • NAID

      10020172629

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15080201
  • [Journal Article] One Argonaute family member, Eif2c2 (Ago2), is essential for development and appears not to be involved in DNA methylation.2007

    • Author(s)
      Morita S, Horii T, Kimura M, Goto Y, Ochiya T & Hatada I^*.
    • Journal Title

      Genomics. 89

      Pages: 687-696

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18016003
  • [Journal Article] Emerging Technologies for Genome-wide DNA Methylation Profiling in Cancer.2006

    • Author(s)
      Hatada I
    • Journal Title

      Crit Rev Oncog. 12(3-4)

      Pages: 205-223

    • Data Source
      KAKENHI-PROJECT-18012010
  • [Journal Article] Microarray analysis of promoter methylation in lung cancers.2006

    • Author(s)
      Fukasawa, M., Kimura, M., Morita, S., Hatada, I., et al.
    • Journal Title

      J Hum Genet. (in press)

    • NAID

      10017479946

    • Data Source
      KAKENHI-PROJECT-15080201
  • [Journal Article] Genomic imprinting in Dicerl-hypomorphic mice.2006

    • Author(s)
      Fukasawa M, Morita S, Kimura M, Horii T, Ochiya T, Hatada I
    • Journal Title

      Cytogenet Genome Res. 113(1-4)

      Pages: 138-143

    • Data Source
      KAKENHI-PROJECT-18012010
  • [Journal Article] Genome-wide profiling of promoter methylation in human.2006

    • Author(s)
      Hatada, I., Fukasawa, M., Kimura, M., Morita, S., Yamada, K., et al.
    • Journal Title

      Oncogene (in press)

    • NAID

      120000908395

    • Data Source
      KAKENHI-PROJECT-15080201
  • [Journal Article] Genomic imprinting in Dicerl-hypomorphic mouse.2006

    • Author(s)
      Fukasawa, M., Morita, S., Kimura, M., Hatada, I., et al.
    • Journal Title

      Cytogenet Genome Res. 113

      Pages: 138-143

    • Data Source
      KAKENHI-PROJECT-15080201
  • [Journal Article] Emerging Technologies for Genome-wide DNA Methylation Profiling in Cancer.2006

    • Author(s)
      Hatada I
    • Journal Title

      Crit Rev Oncog. 12(3-4)

      Pages: 205-223

    • Data Source
      KAKENHI-PROJECT-18016003
  • [Journal Article] Genomic imprinting in Dicerl-hypomorphic mice.2006

    • Author(s)
      Fukasawa M, Morita S, Kimura M, Horii T, Ochiya T, Hatada I
    • Journal Title

      Cytogenet Genome Res. 113(1-4)

      Pages: 138-143

    • Data Source
      KAKENHI-PROJECT-18016003
  • [Journal Article] Genome-wide profiling of promoter methylation in human.2006

    • Author(s)
      Hatada I, Fukasawa M, Kimura M, Morita S, Yamada K, Yoshikawa T, Yamanaka S, Endo C, Sakurada A, Sato M, Kondo T, Horii A, Ushijima T, Sasaki H
    • Journal Title

      Oncogene 25(21)

      Pages: 3059-3064

    • NAID

      120000908395

    • Data Source
      KAKENHI-PROJECT-18012010
  • [Journal Article] Microarray analysis of promoter methylation in lung cancers.2006

    • Author(s)
      Fukasawa M, Kimura M, Morita S, Matsubara K, Yamanaka S, Endo C, Sakurada A, Sato M, Kondo T, Horii A, Sasaki H, Hatada I
    • Journal Title

      J Hum Genet. 51(4)

      Pages: 368-374

    • NAID

      10017479946

    • Data Source
      KAKENHI-PROJECT-18012010
  • [Journal Article] Genome-wide profiling of promoter methylation in human.2006

    • Author(s)
      Hatada I, Fukasawa M, Kimura M, Morita S, Yamada K, Yoshikawa T, Yamanaka S, Endo C, Sakurada A, Sato M, Kondo T, Horii A, Ushijima T, Sasaki H
    • Journal Title

      Oncogene 25(21)

      Pages: 3059-3064

    • NAID

      120000908395

    • Data Source
      KAKENHI-PROJECT-18016003
  • [Journal Article] Emerging Technologies for Genome-wide DNA Methylation Profiling in Cancer2006

    • Author(s)
      Hatada I.
    • Journal Title

      Crit Rev Oncog 12

      Pages: 205-223

    • Data Source
      KAKENHI-PROJECT-15080201
  • [Journal Article] Microarray analysis of promoter methylation in lung cancers.2006

    • Author(s)
      Fukasawa M, Kimura M, Morita S, Matsubara K, Yamanaka S, Endo C, Sakurada A, Sato M, Kondo T, Horii A, Sasaki H, Hatada I
    • Journal Title

      J Hum Genet. 51(4)

      Pages: 368-374

    • NAID

      10017479946

    • Data Source
      KAKENHI-PROJECT-18016003
  • [Journal Article] Normal Reprogramming of Imprinting in Parthenogenetic Female Germ Cells2005

    • Author(s)
      Horii, T., Nagao, Y., Kimura, M., Hatada, I.
    • Journal Title

      Reprod Fetil Dev 17

      Pages: 236-236

    • Data Source
      KAKENHI-PROJECT-15080201
  • [Patent] ゲノムDNAのメチル化検出方法2004

    • Inventor(s)
      畑田出穂
    • Industrial Property Rights Holder
      群馬大学
    • Industrial Property Number
      2004-226103
    • Filing Date
      2004-08-02
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15370092
  • [Patent] ゲノムDNAのメチル化検出方法2002

    • Inventor(s)
      畑田 出穂
    • Industrial Property Rights Holder
      群馬大学
    • Industrial Property Number
      2004-226103
    • Filing Date
      2002-08-02
    • Data Source
      KAKENHI-PROJECT-16011205
  • [Presentation] ヒト子宮内膜がん細胞におけるKMT2変異の意義2022

    • Author(s)
      小林良祐、川端麗香、杉山真言、横堀武彦、森田純代、堀居拓郎、西山正彦、畑田出穂
    • Organizer
      第15回日本エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PROJECT-20H03431
  • [Presentation] ゲノム編集、エピゲノム編集によるモデルマウスの新展開2019

    • Author(s)
      畑田 出穂
    • Organizer
      第40回日本炎症・再生医学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03613
  • [Presentation] エピゲノム研究の新展開2019

    • Author(s)
      畑田 出穂
    • Organizer
      日本ゲノム編集学会 第4回大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03613
  • [Presentation] ゲノム編集からエピゲノム編集まで2019

    • Author(s)
      畑田出穂
    • Organizer
      第30回日本医学会総会2019中部
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03613
  • [Presentation] Epigenome and genome editing of mammals2018

    • Author(s)
      Hatada i
    • Organizer
      Genome Editing Towards Medicinal Applications
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03613
  • [Presentation] Epigenome and genome editing of mammals2018

    • Author(s)
      畑田出穂
    • Organizer
      第9回武田科学振興財団薬科学シンポジウム
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03613
  • [Presentation] エピゲノム編集:特定のDNAメチル化領域を効率よく操作する方法の開発2018

    • Author(s)
      森田純代、堀居拓郎、木村美香、畑田出穂
    • Organizer
      日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-16K07194
  • [Presentation] Lox配列の2ステップ導入による効率的なコンディショナルノックアウトマウスの作製2017

    • Author(s)
      堀居拓郎、森田純代、木村美香、寺脇直美、渋谷海大、畑田出穂
    • Organizer
      日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-15K07687
  • [Presentation] 父性遺伝する食事誘導性肥満におけるインプリント遺伝子の解析と新規インプリント遺伝子の探索について2016

    • Author(s)
      森田純代、中林一彦、河合智子、林恵子、堀居拓郎、木村美香、、亀井康富、小川佳宏、秦健一郎、畑田出穂
    • Organizer
      日本エピジェネティックス研究会第10回年会
    • Place of Presentation
      千里ライフサイエンスセンター
    • Year and Date
      2016-05-19
    • Data Source
      KAKENHI-PROJECT-16K07194
  • [Presentation] Cas9タンパクおよびエレクトロポレーション法を用いたコンディショナルノックアウトマウスの作製2016

    • Author(s)
      堀居拓郎、森田純代、木村美香、寺脇直美、畑田出穂
    • Organizer
      第1回日本ゲノム編集学会
    • Place of Presentation
      広島
    • Year and Date
      2016-09-06
    • Data Source
      KAKENHI-PROJECT-15K07687
  • [Presentation] ES細胞の多能性にはTetによるNr2f2プロモーター領域の脱メチル化が必要であ2016

    • Author(s)
      堀居拓郎、森田純代、木村美香、寺脇直美、木村博信、末武勲、田嶋正二、安部由美子、畑田出穂
    • Organizer
      第10回日本エピジェネティクス研究会年会
    • Place of Presentation
      大阪
    • Year and Date
      2016-05-19
    • Data Source
      KAKENHI-PROJECT-15K07687
  • [Presentation] Tetタンパクは転写因子Nr2f2のプロモーターを脱メチル化することによりES細胞の多能性を維持する2016

    • Author(s)
      堀居拓郎、森田純代、木村美香、寺脇直美、木村博信、末武勲、田嶋正二、安部由美子、畑田出穂
    • Organizer
      第109回日本繁殖生物学会年会
    • Place of Presentation
      相模原
    • Data Source
      KAKENHI-PROJECT-15K07687
  • [Presentation] ES細胞の初期分化にはTetによるNr2f2プロモーター領域の脱メチル化が必要である2015

    • Author(s)
      堀居拓郎、森田純代、木村美香、小林遼平、田村大樹、木村博信、末武勲、田嶋正二、安部由美子、畑田出穂
    • Organizer
      第9回日本エピジェネティクス研究会年会
    • Place of Presentation
      学術総合センター 一橋講堂(東京都千代田区)
    • Year and Date
      2015-05-25
    • Data Source
      KAKENHI-PROJECT-15K07687
  • [Presentation] Tet遺伝子シングル、ダブルおよびトリプルノックアウトES細胞株の特性2015

    • Author(s)
      堀居拓郎、森田純代、木村美香、小林遼平、田村大樹、木村博信、末武勲、田嶋正二、安部由美子、畑田出穂
    • Organizer
      第38回日本分子生物学会年会
    • Place of Presentation
      神戸国際展示場(兵庫県神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-15K07687
  • [Presentation] ミトコンドリアにおける翻訳停滞解消機構の解明2015

    • Author(s)
      村里旺彦,小暮裕幸,堀居拓郎,浅川直紀,畑田出穂,行木信一
    • Organizer
      平成27年度日本生化学会関東支部例会
    • Place of Presentation
      新潟日報メディアシップ(新潟県)
    • Year and Date
      2015-06-20
    • Data Source
      KAKENHI-PROJECT-15K06945
  • [Presentation] Stalled-ribosome rescue factors are essential for mitochondrial function.2015

    • Author(s)
      Shizuka Kobayasi, Akihiko Murasato, Sho Arai, Hiroyuki Kogure, Takuro Horii, Izuho Hatada and Nobukazu Nameki
    • Organizer
      2nd International Symposium of Gunma University Medical Innovation (GUMI2015)
    • Place of Presentation
      群馬大学昭和キャンパス(群馬県)
    • Year and Date
      2015-12-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06945
  • [Presentation] 半数体ES細胞とCRISPR/Casを用いた高効率ゲノム編集2013

    • Author(s)
      堀居 拓郎,森田 純代,木村 美香,小林 遼平,田村 大樹,高橋 陵宇,木村 博信,末武 勲,大畑 広和, 岡本 康司,田嶋 正二,落谷 孝広,安部 由美子,畑田 出穂
    • Organizer
      ゲノム編集研究会
    • Place of Presentation
      東広島
    • Data Source
      KAKENHI-PROJECT-24613002
  • [Presentation] 半数体胚由来2倍体ES細胞の移植医療への利用の可能性2013

    • Author(s)
      堀居拓郎、小林遼平、田村大樹、森田純代、木村美香、畑田出穂
    • Organizer
      日本エピジェネティクス研究会
    • Place of Presentation
      奈良
    • Data Source
      KAKENHI-PROJECT-24613002
  • [Presentation] 低酸素培養は初期胚や胎盤にDNAメチル化異常を引き起こす2012

    • Author(s)
      堀居拓郎、柳澤永吉、森田純代、木村美香、畑田出穂
    • Organizer
      第6回日本エピジェネティクス研究会年会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24613002
  • [Presentation] Risk of Epigenetic Changes is Increased by Low Oxygen in ART Embryo Cultures2012

    • Author(s)
      堀居拓郎、柳澤永吉、森田純代、木村美香、畑田出穂
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      博多
    • Data Source
      KAKENHI-PROJECT-24613002
  • [Presentation] 初期胚の低酸素培養は初期胚や胎盤にDNAメチル化異常を引き起こす2012

    • Author(s)
      堀居拓郎、柳澤永吉、森田純代、木村美香、畑田出穂
    • Organizer
      第105回日本繁殖生物学会年会
    • Place of Presentation
      つくば
    • Data Source
      KAKENHI-PROJECT-24613002
  • [Presentation] Profiling and characterization of DNA methylation targets2009

    • Author(s)
      Hatada I
    • Organizer
      JapanDenmark Joint Workshop on "Molecular Cancer Research"
    • Place of Presentation
      Tokyo
    • Data Source
      KAKENHI-PROJECT-20016002
  • [Presentation] Profiling and characterization of DNA methylation targets2009

    • Author(s)
      Hatada I
    • Organizer
      Japan-Denmark Joint Workshop on "Molecular Cancer Research"
    • Place of Presentation
      Tokyo
    • Data Source
      KAKENHI-PROJECT-20012009
  • [Presentation] Development of genome-wide DNA methylation analysis method and applications2009

    • Author(s)
      Hatada I
    • Organizer
      68^<th> Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      Yokohama, Japan
    • Data Source
      KAKENHI-PROJECT-20012009
  • [Presentation] Development of genome-wide DNA methylation analysis method and applications2009

    • Author(s)
      Hatada I
    • Organizer
      68^<th> Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      Yokohama, Japan
    • Data Source
      KAKENHI-PROJECT-20016002
  • [Presentation] Profiling of DNA methylation targets2008

    • Author(s)
      Hatada I
    • Organizer
      Decoding Epigenetic Code
    • Place of Presentation
      Tokyo
    • Data Source
      KAKENHI-PROJECT-20012009
  • [Presentation] Profiling of DNA methylation targets2008

    • Author(s)
      Hatada I
    • Organizer
      Decoding Epigenetic Code
    • Place of Presentation
      Tokyo
    • Data Source
      KAKENHI-PROJECT-20016002
  • [Presentation] Genome-wide DNA methyaltion analysis by MIAMI.2007

    • Author(s)
      Hatada I^*
    • Organizer
      Epigenomics, Technology, Products, and Obstacles
    • Place of Presentation
      Osaka, Japan
    • Year and Date
      2007-06-14
    • Data Source
      KAKENHI-PROJECT-18016003
  • [Presentation] Genome-wide DNA methyaltion analysis by MIAMI.2007

    • Author(s)
      Hatada I^*
    • Organizer
      Epigenomics, Technology, Products, and Obstacles
    • Place of Presentation
      Osaka, Japan
    • Year and Date
      2007-06-14
    • Data Source
      KAKENHI-PROJECT-18012010
  • [Presentation] CRISPR/Cas9システムによる哺乳類半数体ES 細胞のゲノム操作

    • Author(s)
      堀居 拓郎,森田 純代,木村 美香,小林 遼平,田村 大樹,高橋 陵宇,木村 博信,末武 勲,大畑 広和, 岡本 康司,田嶋 正二,落谷 孝広,安部 由美子,畑田 出穂
    • Organizer
      日本分子生物学会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-24613002
  • [Presentation] CRISPR/Casと半数体ES細胞を用いたトリプルノックアウトおよび大規模染色体欠失の作製

    • Author(s)
      堀居 拓郎,森田 純代,木村 美香,高橋 陵宇,木村 博信,末武 勲,田嶋 正二, 落谷 孝広,畑田 出穂
    • Organizer
      日本繁殖生物学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24613002
  • [Presentation] 半数体胚由来2倍体ES 細胞(hddES)- 再生医療における新たな多能性幹細胞の選択肢

    • Author(s)
      小林 遼平,堀居 拓郎,田村 大樹,森田 純代,木村 美香,安部 由美子,畑田 出穂
    • Organizer
      日本分子生物学会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-24613002
  • []

  • 1.  HORII Takuro (00361387)
    # of Collaborated Projects: 14 results
    # of Collaborated Products: 58 results
  • 2.  Morita Sumiyo (40589264)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 9 results
  • 3.  OBATA Yayoi (70312907)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 4.  落谷 孝広 (60192530)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 5.  小林 良祐 (30802855)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 6.  川端 麗香 (90721928)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 7.  堀井 明 (40249983)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 14 results
  • 8.  横堀 武彦 (60420098)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  Nohara Keiko (50160271)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  Nakabayashi Kazuhiko (10415557)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 11.  Suzuki Takehiro (60425494)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  Okamura Kazuyuki (50736064)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  KONO Tomohiro (80153485)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  MIYANO Takashi (80200195)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  Nameki Nobukazu (80302959)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 16.  中井 謙太 (60217643)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 17.  秦 健一郎 (60360335)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  澁谷 海大 (70786839)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  西山 正彦 (20198526)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 20.  大日方 英 (50332557)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  調 憲 (70264025)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  安部 由美子 (70261857)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 23.  河野 大輔 (10382904)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  Matsushita Junya
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  末武 勲
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  田嶋 正二
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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