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ASAMOTO Makoto  朝元 誠人

ORCIDConnect your ORCID iD *help
… Alternative Names

朝元 誠人  アサモト マコト

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Researcher Number 50212494
Other IDs
Affiliation (based on the past Project Information) *help 2007: Nagoya City University, Graduate School of Medical Science, Associate Professor
2006: 名古屋市立大学, 大学院医学研究科, 助教授
2005: 名古屋市立大学, 大学院・医学研究科, 助教授
2001: Nagoya City University, Medical School, Associate Professor, 医学部, 助教授
1999 – 2000: 名古屋市立大学, 医学部, 講師 … More
1997 – 1998: 国立がんセンター, 化学療法部, 室長
1997: 国立がんセンター, 研究所・化学療法部, 室長
1991: 大阪市立大学, 医学部, 講師 Less
Review Section/Research Field
Principal Investigator
Experimental pathology
Except Principal Investigator
Experimental pathology / Experimental pathology / Biological Sciences
Keywords
Principal Investigator
cancer stem cells / steroid hormone / androgen / cell culture / Prostate cancer / マイクロアレイ / 可移植腫瘍 / ヌードマウス / トランスジェニック動物 / がん … More / 前立腺 / siRNA / GSTP / CD133 / ラット / 細胞株 / 前立腺がん / がん幹細胞 / ステロイドホルモン / アンドロゲン / 培養細胞 / 前立腺癌 … More
Except Principal Investigator
DMAB / 前立腺 / ラット / トランスジェニックラット / Cadmium / PhIP / prostate / rat / 前立腺癌 / MNU / 乳腺発がん / 発がん感受性 / c-Ha-ras / Screening method / Carcinogen / Prostate / oncomoduline / マイクロアレイ / スクリーニング / 発がん物質 / SV40T antigen / carcinogenesis / genetically modified animals / bioassay / chemopreventor / transgenic / 発がん / transgenic rat / 遺伝子改変物質 / SV40 T antigen / 発癌 / 遺伝子改変動物 / 早期検索系 / 発癌抑制物質 / prostate cancer cell line / prostatic intraepithelial neoplasia / prostate carcinogenesis / 4-nonylphenol / endocrine disruptor / 3,2'-dimethy1-4-aminobiphenyl / ノニルフェノール / 幼若令 / テストステロン / 3,2'-dimethyl-4-aminobiphenyl / ノニフェノール / 前立線癌細胞株 / 前立腺癌細胞株 / PIN / F344ラット / DMAB発癌モデル / 発癌修飾作用 / 4-ノニルフェノール / 内分泌かく乱物質 / Histone deacetylase inhibitors / Hydroxyapatite / Phenolic compounds / Terupenoids / Carotenoids / Tumor initiation / Tumor promotion / Cancer chemoprevention / WAF-1 / 一酸化窒素 / d-リモネン / タイ国産野菜 / グリチルレチン酸モノグルクロナイド / イソリクイリチゲニン / 天然カロテノイド / 化学予防 / ヒストン脱アセチル化酵素阻害剤 / ヒドロキシアパタイト / フェノール性化合物 / テルペノイド / カロテノイド類 / 発がんイニシエーション / 発がんプロモーション / がん化学予防 / 遺伝子発現 / cDNA array / トランスジェニック / SV40T抗原 / 抗アンドロゲン剤 / アポトーシス / NMBA / 食道発がん / 導入遺伝子変異 / BBN / DMBA / 膀胱発がん / dehydroepiandrosterone / indomethacin / phytic acid / 発癌抗プロモ-タ- / 発癌インヒビション / 発癌プロモ-ション / 膀胱二段階発癌 Less
  • Research Projects

    (9 results)
  • Research Products

    (23 results)
  • Co-Researchers

    (19 People)
  •  Development of a in vivo screening method for evaluation prostate carcinogenic potential in chemicals

    • Principal Investigator
      SHIRAI Tomoyuki
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Nagoya City University
  •  Mechanistic analysis for androgen independent growth of prostate cancersPrincipal Investigator

    • Principal Investigator
      ASAMOTO Makoto
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Nagoya City University
  •  アンドロゲン依存性ラット前立腺癌のアポトーシスにかかわる遺伝子の解明

    • Principal Investigator
      SHIRAI Tomoyuki
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Nagoya City University
  •  Establishment of medium-term bioassay methods for detecting chemopreventors on prostate carcinogenesis using transgenic rat model

    • Principal Investigator
      IMAIDA katsumi
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Kagawa Medical University
      Nagoya City University
  •  Modifying effects of a possible endocrine disrupting chemical on rat prostate carcinogenesis

    • Principal Investigator
      SHIRAI Tomoyuki
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Nagoya City University
  •  c-Ha-rasトランスジェニックラットの発がん感受性の解析

    • Principal Investigator
      鳥山 弘靖
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  c-Ha-rasトランスジェニックラットの発がん感受性の解析

    • Principal Investigator
      鳥山 弘靖
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  Cancer chemoprevention

    • Principal Investigator
      NISHINO Hoyoku
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  膀胱発癌の修飾に関する酸化防止剤の意義とその機構

    • Principal Investigator
      福島 昭治
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Osaka City University

All 2008 2007 2006 2005

All Journal Article Presentation Book

  • [Book] Carcinogenesis and Modification of Carcinogenesis2005

    • Author(s)
      Asamoto, M.
    • Publisher
      Kerala : Research Signpost
    • Data Source
      KAKENHI-PROJECT-17590356
  • [Book] Carcinogenesis and Modification of Carcinogenesis2005

    • Author(s)
      Asamoto, M
    • Publisher
      Kerala:Research Signpost
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590356
  • [Journal Article] Glutathione S-transferase pi mediates proliferation of androgen independent prostate cancer cells2008

    • Author(s)
      Hokaiwado, N., Takeshita, F., Naiki-Ito, A., Asamoto, M., Ochiya, T., Shirai, T
    • Journal Title

      Carcinogenesis., Epub ahead of print

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590356
  • [Journal Article] Optimization ofan animal test protocol for toxicogenomics studies (2); A-cross-Laboratory gene expression analysis2007

    • Author(s)
      Sumida, K., Saito, K., Oeda, K., Otsuka, M., Tsujimura, K., Miyaura, H., Asamoto, M., Shirai, T
    • Journal Title

      Toxicol. Sci. 32

      Pages: 33-45

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590377
  • [Journal Article] Protective effects of citrus nobiletin and auraptene in transgenic rats developing adenocarcinoma of the prostate (TRAP) and human prostate carcinoma cells2007

    • Author(s)
      Tang, M., Ogawa, K., Asamoto, M., Hokaiwado, N., Azman, S., Suzuki, S., Takahashi, S., Tanaka, T., Ichikawa, K., Shirai, T
    • Journal Title

      Cancer Sci. 98

      Pages: 471-477

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590377
  • [Journal Article] Protective effects of citrus nobiletin and auraptene in transgenic rats developing adenocarcinoma of the prostate (TRAP) and human prostate carcinoma cells2007

    • Author(s)
      Tang, M., Ogawa, K., Asamoto, M., Hokaiwado, N., Azman, S., Suzuki, S., Takahashi, S., Tanaka, T., Ichikawa, K., Shirai, T
    • Journal Title

      Cancer Sc 98

      Pages: 471-477

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590356
  • [Journal Article] Optimization of an animal test protocol for toxicogenomics studies (1); Requirement study of a protocol2007

    • Author(s)
      Sumida, K., Saito, K., Oeda, K., Otsuka, M., Tsujimura, K., Miyaura, H., Asamoto, M., Shirai, T
    • Journal Title

      Toxicol. Sci. 32

      Pages: 19-32

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590377
  • [Journal Article] Limited effects of disrupted Gap Junctions in the liver on multi-organ carcinogenesis induced by Diisopropanolnitrosamine in the mutant Connexin 32 Transgenic rat2006

    • Author(s)
      Murasaki, T., Asamoto, M., Hokaiwado, N., Ogawa, K., Shirai, T
    • Journal Title

      J Toxicol Pathol 19

      Pages: 93-97

    • NAID

      130000065694

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590356
  • [Journal Article] Inhibition of prostate carcinogenesis in probasin/SV40 T antigen transgenic rats by leuprorelin, a luteinizing hormone-releasing hormone agonist2006

    • Author(s)
      Said, M., Hokaiwado, N., Tang, M., Ogawa, K., Suzuki, S., Ghanem, H. N., Esmat, A. Y., Asamoto, M., Fawzia, M. R., Shirai, T
    • Journal Title

      Cancer Sci 97

      Pages: 459-467

    • NAID

      10018176080

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590356
  • [Journal Article] Close relation of Transforming Growth Factor a positive hepatic foci to hepatocellular tumor development in the rat2006

    • Author(s)
      Tamano, S., Kawabe, M., Ichihara, T., Hagiwara, A, Sano, M., Asamoto, M., Shirai, T
    • Journal Title

      J Toxicol Pathol 19

      Pages: 99-106

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590356
  • [Journal Article] Prediction of carcinogenic potential by a toxicogenomic approach using rat hepatoma cells2006

    • Author(s)
      Tsujimura, K., Asamoto, M., Shugo, S., Hokaiwado, N., Ogawa, K., Shirai, T
    • Journal Title

      Cancer Sci 97

      Pages: 1002-1010

    • NAID

      10019377814

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590356
  • [Journal Article] Characterization and application of polycolonal antibodies that specifically recognize JC virus large T antigen2006

    • Author(s)
      Sunden, Y., Suzuki, T., Orba, Y., Umemura, T., Asamoto, M., Nagashima, K., Tanaka, S., Sawa, H
    • Journal Title

      Acta. Neuropathol 111

      Pages: 379-387

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590356
  • [Journal Article] Prediction of carcinogenic potential by a toxicogenomic approach using rat hepatoma cells2006

    • Author(s)
      Tsujimura, K., Asamoto, M., Shugo, S., Hokaiwado, N., Ogawa, K., Shirai, T
    • Journal Title

      Cancer Sci. 97

      Pages: 1002-1010

    • NAID

      10019377814

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590377
  • [Journal Article] Transgenic disruption of gap junctional intercellular communication protects against hepatotoxicity while increasing susceptibility to liver carcinogenesis in rats, in Carcinogenesis and Modification of Carcinogenesis2005

    • Author(s)
      Asamoto, M., Hokaiwado, N., Shirai, T
    • Journal Title

      Edited by T. Tanaka, H. Tsuda. Kerala, Research Signpost

      Pages: 1-7

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590356
  • [Journal Article] Downregulation of apoptosis revealed by laser microdissection and cDNA microarray analysis of related genes in rat liver preneoplastic lesions2005

    • Author(s)
      Ogawa, K., Asamoto, M., Suzuki, S., Tsujimura, K., Shirai, T
    • Journal Title

      Med. Mol. Morphol 38

      Pages: 23-29

    • NAID

      10018374411

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590356
  • [Journal Article] Influence of atrazine administration and reduction of calorie intake on prostate carcinogenesis in probasin/SV4OT antigen transgenic rats2005

    • Author(s)
      Kandori, H., Suzuki, S., Asamoto, M., Murasaki, T., Tang, M., Ogawa, K., Shirai, T
    • Journal Title

      Cancer Sci 96

      Pages: 221-226

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590356
  • [Journal Article] Harman and norharman suppressed but NaNO2 enhanced the development of preneoplastic liver cell foci in 2-amino-3, 8-dimethylimidazo[4,5-f] quinoxaline (MeIQx)-reated rats2005

    • Author(s)
      Sugiura, S., Asamoto, M., Hokaiwado, N., Hirose, M., Shirai, T
    • Journal Title

      J., Toxicol. Pathol 18

      Pages: 99-104

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590356
  • [Journal Article] Tbx3 expression is related to apoptosis and cell proliferation in rat bladder both hyperplastic epithelial cells and carcinoma cells2005

    • Author(s)
      Ito, A., Asamoto, M., Hokaiwado, N., Takahashi, S., Shirai, T
    • Journal Title

      Cancer Lett 219

      Pages: 105-112

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590356
  • [Journal Article] Equivocal impact of transplacental and lactational exposure to a food-derived carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-3]pyridine, on prostate and colon lesion development in F344 rats2005

    • Author(s)
      Ikeda, Y., Cho, Y. M., Takahashi, S., Tang, M., Asamoto, M., Ogawa, K., Shirai, T
    • Journal Title

      Cancer Lett 224

      Pages: 23-30

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590356
  • [Journal Article] Lack of effects of 1439 MHz electromagnetic near field exposure on the blood-brain barrier in immature and young rats2005

    • Author(s)
      Kuribayashi, M., Wang, J., Fujiwara, O., Doi, Y., Nabae, K., Tamano, S., Ogiso, T., Asamoto, M., Shirai, T
    • Journal Title

      Bioelectromagnetics 26

      Pages: 578-588

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590356
  • [Presentation] cDNA microarray analysis of genes which specifically alteredin the rat prostate after treatment with prostate carcinogens2008

    • Author(s)
      Futakuchi, M., Sato, S., Sumida, K., Saito, K., Takahashi, S., Asamoto, M., Shirai, T
    • Organizer
      The 24th Annual Meeting of the Japanese Society of Toxicologic Pathology
    • Place of Presentation
      Nagoya
    • Year and Date
      2008-02-07
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590377
  • [Presentation] Establishment and characterization of rat prostate carcinoma cell lines derived from the Probasin/SV40Tag transgenic rat model2007

    • Author(s)
      Asamoto, M., Hokaiwado, N., Shirai, T
    • Organizer
      Proceedings of the 18th Workshop on Prostate Cancer
    • Place of Presentation
      Tokyo
    • Year and Date
      2007-09-28
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590356
  • [Presentation] Probasin/SV40Tag導入トランスジェニックラット(TRAP)前立腺癌由来ヌードマウス可移植性細胞株の樹立とその性質2007

    • Author(s)
      朝元 誠人
    • Organizer
      第18回前立腺がんワークショップ
    • Place of Presentation
      国立がんセンター研究所
    • Year and Date
      2007-09-28
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590356
  • 1.  SHIRAI Tomoyuki (60080066)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 5 results
  • 2.  鳥山 弘靖 (70156537)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  津田 洋幸 (10163809)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  NISHINO Hoyoku (10079709)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  YAMAMOTO Noriko (10280629)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  OHIGASHI Hajime (80026583)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  OKUYAMA Tohru (40087789)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  TAKASUKA Nobuo (80270677)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  NAGASAWA Hiroshi (10076987)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  IMAIDA katsumi (90160043)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  SAOO kousuke (80314912)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  福島 昭治 (00137077)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  鰐渕 英機 (90220970)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  大谷 周造 (80047068)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  落谷 孝広 (60192530)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  二口 充 (60275120)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  外岩戸 尚美 (70381853)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  鈴木 周五 (60363933)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 19.  TOYODA Naomi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 9 results

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