hashimoto noriyoshi 橋本憲佳

… Alternative Names

Hashimoto Noriyoshi 橋本憲佳

HASHIMOTO Noriyoshi 橋本憲佳

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Researcher Number	50242524
Other IDs
External Links
Affiliation (Current)	2025: 金沢大学, 疾患モデル総合研究センター, 准教授
Affiliation (based on the past Project Information) *help	2018 – 2020: 金沢大学, 学際科学実験センター, 准教授 2013: 金沢大学, 金沢大学, 准教授 2007 – 2013: Kanazawa University, 学際科学実験センター, 准教授 2003 – 2006: Kanazawa Univ., Advanced Science Research Center, Associate Professor, 学際科学実験センター, 助教授 2002: 金沢大学, 医学系研究科, 助手 1995 – 2001: 金沢大学, 医学部, 助手 1992 – 1993: 金沢大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Laboratory animal science / Laboratory animal science / Basic Section 42040:Laboratory animal science-related Except Principal Investigator Biological Sciences / Laboratory animal science / Laboratory animal science / Immunology / Cell biology
Keywords	Principal Investigator 血液疾患 / 遺伝子改変動物 / リソソーム病 / 血球貪食症候群 / 病態モデル / 実験動物学 / 偽妊娠マウス / レシピエントマウス / 近交系 / 胚移植 … More / レシピエント / Malignancy / Skin tumor / Chemical carcinogen / Galactose / Tumor antigen / Galactosyltransferase / Knockout mice / Carbohydrate / 化学発癌 / ノックアウトマウス / ガラクトース / 基幹糖鎖構造 / 癌特異抗原 / 糖鎖抗原 / 糖転移酵素遺伝子 / 赤血球 / マクロファージ / ゴーシェ細胞 / 実験動物 / レグマイン / 疾患モデルマウス / プロテアーゼ / リソソーム蓄積症 / AEP / Legumain / life span / Immunoresponse / Natural killer activity / Body-core Temperature / Cold-induced thermogenesis / Oxygen consumption / Systemic carnitine deficiency / JVS mice / SCIDマウス / 血液幹細胞 / 免疫細胞分化 / 免疫グロブリン / V(D)J recombination / leaky現象 … More Except Principal Investigator ガラクトース転移酵素 / ノックアウトマウス / 糖鎖 / 遺伝子トラップ / 糖転移酵素遺伝子 / 胎生致死 / Inflammation / Knockout mice / 炎症反応 / IL-1 / scid / beige / xid / マウス / 骨髄移植 / IgA腎症 / アデノウイルスベクター / 中胚葉誘導 / 原腸陥入 / 発生制御転写因子 / セレクチン / Embryonic lethal / Skin wound healing / Selectins / Galactosyltransferase / Carbohydrate / コンジェニックマウス / 遅延型過敏症 / ガラクトース糖鎖 / 皮膚創傷治癒 / Apoptosis / Stress Response / RheumatoidArthritis / Contact Hypersensitivity / Antibody Production / エンドトキシンショック / ディファレンシャル・ディスプレイ / 細菌誘導性肝炎 / T細胞フライミング / アポトーシス / ストレス応答 / 関節リウマチ / 接触過敏症反応 / 抗体産生 / cultured cells / carnitine / transporter / cardiac hypertrophy / sperm / fatty liver / animal model / mice / 遺伝子量 / 培養細胞 / カルニチン / トランスポーター / 心肥大 / 精子 / 脂肪肝 / 疾患モデル / bone marrow / UV irradiation / carcinogenesis / immunodeficient / mouse / NK細胞 / 可移植性 / 免疫不全 / 骨髄細胞 / 発がん / 紫外線 / nude / ホーミング / 骨髄幹細胞 / 記憶・学習 / ミオパチー / 骨随移植 / 行動解析 / シアル酸生合成 / ネフローゼ / 遺伝子ノックアウトマウス / 高IgA血症 / 脾臓肥大 / ミエリン塩基性タンパク質 / 実験的自己免疫性脳脊髄炎 / 抗原提示 / 抗原プロセッシング / アスパラギンエンドペプチダーゼ / 細胞周期 / DNA複製 / 胚性幹細胞 / トランスジェニックマウス / Orc4 / 複製開始点認識複合体 / 初期発生 / 浸潤・転移 / ルイス抗原 / 基幹糖鎖構造 / 腫瘍糖鎖抗原 / メチルコラントレン / シアリルLe^x / 腫瘍抗原 / 胎盤形成 / 遅延型接触過敏症反応 Less

Development of new albino inbred strain mice for embryo-transfer recipientPrincipal Investigator
- Principal Investigator
  
  Hashimoto Noriyoshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Kanazawa University
Identification of novel homing molecules of hematopoietic stem cells and development of efficient bone marrow transfer methods by modifying carbohydrates
- Principal Investigator
  
  ASANO Masahide
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  Kanazawa University
Characterization of AEP/Legumain-deficient mice as a new model of lysosome diseasePrincipal Investigator
- Principal Investigator
  
  HASHIMOTO Noriyoshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Kanazawa University
Development of mouse models for human diseases caused by impaired glycosylation and analysis of their mechanisms
- Principal Investigator
  
  ASANO Masahide
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Kanazawa University
Characterization of AEP/Legumain-deficient mice as a model of hemophagocytic syndrome-like diseasePrincipal Investigator
- Principal Investigator
  
  HASHIMOTO Noriyoshi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Kanazawa University
β4-ガラクトース転移酵素-I欠損によるIga腎症発症機構の解析
- Principal Investigator
  
  浅野雅秀
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
自己免疫疾患におけるアスパラギンエンドペプチダーゼによる免疫記憶の調節
- Principal Investigator
  
  浅野雅秀
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
ORC4変異マウスを用いた個体レベルでの細胞周期研究
- Principal Investigator
  
  浅野雅秀
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cell biology
- Research Institution
  Kanazawa University
Functional analysis of carbohydrate antigens in chemically induced tumor cells derived from beta-1,4-galactosyltransferase-I knockout micePrincipal Investigator
- Principal Investigator
  
  HASHIMOTO Noriyoshi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Kanazawa University
改良遺伝子トラップ法による新規発生制御遺伝子の単離と機能解析
- Principal Investigator
  
  浅野雅秀
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
改良遺伝子トラップ法による新規発生制御遺伝子の単離と機能解析
- Principal Investigator
  
  浅野雅秀
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
糖転移酵素遺伝子欠損マウスを用いた発癌・転移における糖鎖機能の解析
- Principal Investigator
  
  浅野雅秀
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
Elucidation of individual roles of the galactosyl|ransferase gene family using gene knockout mice
- Principal Investigator
  
  ASANO Masahide
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Kanazawa University
ガラクトース転移酵素遺伝子ノックアウトマウスを用いた糖鎖機能の解析
- Principal Investigator
  
  浅野雅秀
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kanazawa University
糖転移酵素遺伝子欠損マウスを用いた発癌・転移における糖鎖機能の解析
- Principal Investigator
  
  浅野雅秀
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
ガラクトース転移酵素遺伝子ノックアウトマウスを用いた糖鎖機能の解析
- Principal Investigator
  
  ASANO Masahide
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kanazawa University
Functional analysis of IL-1 in immune and stress responses using gene knockout mice
- Principal Investigator
  
  ASANO Masahide
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Kanazawa University
  The University of Tokyo
カルニチン欠乏症(JVS)マウスの病態発生に及ぼす環境ストレスの影響Principal Investigator
- Principal Investigator
  
  橋本憲佳
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  Kanazawa University
Evaluation of disease model traits in cultured cells derived from carnitine deficient JVS mice
- Principal Investigator
  
  HAYAKAWA Jun-ichiro
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Kanazawa University
免疫担当細胞の分化研究モデルとしてのLeaky SCIDマウスの確立Principal Investigator
- Principal Investigator
  
  橋本憲佳
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  Kanazawa University
Characterization of mice carrying multiple mutant genes which cause the different immunological defects.
- Principal Investigator
  
  HAYAKAWA Jun-ichiro
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  Kanazawa University

All 2018 2014 2011 2009 2007 2006 2005 2004 2003

All Journal Article Presentation

[Journal Article] Asparaginyl endopeptidase欠損マウスにおける血球貪食症候群様病態について2011
- Author(s)
  浅野雅秀, 橋本憲佳
- Journal Title
  
  血液内科
  
  Volume: 63(6) Pages: 634-639
- URL
  http://www.kahyo.com/item/KS201112-636
- Data Source
  KAKENHI-PROJECT-21500387
[Journal Article] Mice lacking asparaginyl endopeptidase develop disorders resembling hemophagocytic syndrome2009
- Author(s)
  Chi-Bun Chan, Michiyo Abe, Noriyoshi Hashimoto, Chunhai Hao, Ifor R. Williams, Xia Liu, Shinji Nakao, Akitsugu Yamamoto, Chengyun Zheng, Jan-Inge Henter, Marie Meeths, Magnus Nordenskjold, Shi-Yong Li, Ikuko Hara-Nishimura, Masahide Asano, Keqiang Ye
- Journal Title
  
  Proc Natl Acad Sci U S A 106(2)
  
  Pages: 468-473
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500325
[Journal Article] Mice lacking asparaginyl endopeptidase develop disorders resembling hemophagocytic syndrome.2009
- Author(s)
  Chan, C. B., Abe, M., Hashimoto, N., et al.
- Journal Title
  
  Proceeding of the National Academy of Sciences of the United States of America 106
  
  Pages: 468-473
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500325
[Journal Article] Development of immunoglobulin A nephropathy-like disease in β-1, 4-galactosyltransferase-I deficient mice2007
- Author(s)
  Nishie, T., Miyaishi, O., Azuma, H., Kameyama, A., Naruse, C., Hashimoto, N., Yokoyama, H., Narimatsu, H., Wada, T., Asano, M.
- Journal Title
  
  Am. J. Pathol. 170
  
  Pages: 447-459
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300144
[Journal Article] Characterization of serum IgA in beta4GalT I-deficient mice developing IgAN-like disease.2005
- Author(s)
  Asano M, Nishie T, Miyaishi O, Azuma H, Kameyama A, Naruse C, Hashimoto N, Yokoyama H, Narimatsu H, Wada T.
- Journal Title
  
  Nephrology (Carlton) 10 Suppl 6
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15500298
[Journal Article] Analysis of human IgA nephropathy-like disease in galactosyltransferase KO mice.2004
- Author(s)
  Nishie T, Miyaishi O, Naruse C, Hashimoto N, Asano M.
- Journal Title
  
  Nephrology (Carlton) 9 Suppl 2
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15500298
[Journal Article] Impaired selectin-ligand biosynthesis and reduced inflammatory responses in beta-1,4-galactosyltransferase-I-deficient mice.2003
- Author(s)
  Asano M, Nakae S, Kotani N, Shirafuji N, Nambu A, Hashimoto N, Kawashima H, Hirose M, Miyasaka M, Takasaki S, Iwakura Y.
- Journal Title
  
  Blood 102(5)
  
  Pages: 1678-1685
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15500298
[Presentation] 胚移植レシピエントのための新規アルビノ近交系マウスの開発2018
- Author(s)
  橋本憲佳，中村由季子，井之上幸範
- Organizer
  第65回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-18K06026
[Presentation] 造血幹細胞の骨髄ホーミングにおける糖鎖の役割2014
- Author(s)
  橋本憲佳, 田畑佳祐, 高垣聡一郎, 西江敏和, 浅野雅秀
- Organizer
  第61回日本実験動物学会
- Place of Presentation
  札幌コンベンションセンター(北海道)
- Year and Date
  2014-05-15
- Data Source
  KAKENHI-PROJECT-23650232
[Presentation] 造血幹細胞の骨髄ホーミングにおける糖鎖の役割2014
- Author(s)
  橋本憲佳，田畑佳祐，高垣聡一郎，西江敏和，浅野雅秀
- Organizer
  第61回日本実験動物学会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Data Source
  KAKENHI-PROJECT-23650232
[Presentation] AEP/Legumain欠損マウス骨髄における血球貪食症候群様病態の解析2011
- Author(s)
  橋本憲佳
- Organizer
  第58回日本実験動物学会総会
- Place of Presentation
  タワーホール船堀(東京)
- Year and Date
  2011-05-25
- Data Source
  KAKENHI-PROJECT-21500387
[Presentation] AEP/Legumain欠損マウスにおける血球貪食症候群様病態の解析2009
- Author(s)
  橋本憲佳
- Organizer
  第56回日本実験動物学会
- Place of Presentation
  大宮ソニックシティ(埼玉県)
- Year and Date
  2009-05-15
- Data Source
  KAKENHI-PROJECT-21500387
[Presentation] AEP/Legumain 欠損マウスにおける血球貪食症候群様病態の解析2009
- Author(s)
  橋本憲佳, 他
- Organizer
  第56回日本実験動物学会
- Place of Presentation
  大宮ソニックシティ (埼玉県)
- Data Source
  KAKENHI-PROJECT-21500387
[Presentation] AEP/Legumain欠損マウスにおける血球貪食症候群様病態の解析2007
- Author(s)
  安陪道代、橋本憲佳、宮石理、中尾眞二、西村いくこ、浅野雅秀
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18500325
[Presentation] Legumain(AEP)遺伝子欠損マウスは血球貪食症候群様の病態を呈する2006
- Author(s)
  安陪道代, 橋本憲佳, 宮石理, 西村いくこ, 浅野雅秀
- Organizer
  第53回日本実験動物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-18500325

1. ASANO Masahide (50251450)

# of Collaborated Projects: 16 results

# of Collaborated Products: 10 results
2. SUGIHARA Kazushi (10377418)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. 成瀬智恵 (30372486)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. YOSHIHARA Toru (00401935)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. SUDO Katsuko (50126091)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. IWAKURA Yoichiro (10089120)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. HAYAKAWA Jun-ichiro (50110622)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. ISHIGAKI Yasuto (20232275)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. AKAO Nobuaki (00126559)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. OHNO Shinsuke (70019868)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NIKAIDO Osamu (60019669)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KUWAJIMA Masamichi (00205262)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TAMAI Ikumi (20155237)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 西村いくこ (00241232)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

hashimoto noriyoshi 橋本 憲佳

Hashimoto Noriyoshi 橋本 憲佳

HASHIMOTO Noriyoshi 橋本 憲佳

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Development of new albino inbred strain mice for embryo-transfer recipientPrincipal Investigator

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Characterization of AEP/Legumain-deficient mice as a new model of lysosome diseasePrincipal Investigator

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Characterization of AEP/Legumain-deficient mice as a model of hemophagocytic syndrome-like diseasePrincipal Investigator

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Functional analysis of carbohydrate antigens in chemically induced tumor cells derived from beta-1,4-galactosyltransferase-I knockout micePrincipal Investigator

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hashimoto noriyoshi 橋本憲佳

Hashimoto Noriyoshi 橋本憲佳

HASHIMOTO Noriyoshi 橋本憲佳