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OZAKI Keiichi  尾崎 恵一

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… Alternative Names

OZAKI Kei-ichi  尾崎 恵一

OZAKI Ken-ichi  尾崎 惠一

尾崎 惠一  オザキ ケイイチ

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Researcher Number 50252466
Other IDs
Affiliation (Current) 2025: 同志社女子大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help 2020: 同志社女子大学, 薬学部, 教授
2018 – 2019: 大阪薬科大学, 薬学部, 教授
2016 – 2017: 大阪薬科大学, 薬学部, 教授(移行)
2014 – 2015: 長崎大学, 医歯薬学総合研究科(薬学系), 准教授
2012 – 2013: 長崎大学, 医歯(薬)学総合研究科, 准教授 … More
2008 – 2012: Nagasaki University, 大学院・医歯薬学総合研究科, 准教授
2009 – 2010: 長崎大学, 大学院・医歯薬学研究科, 准教授
2007: Nagasaki University, 医歯薬学総合研究科, 准教授
2006: Nagasaki University, Graduate School of Biomedical Sciences, Associate Professor, 大学院医歯薬学総合研究科, 助教授
2002 – 2005: 長崎大学, 大学院・医歯薬学総合研究科, 助教授
2004: Nagasaki University, Graduate School of Biomedical Sciences, Associate Professor, 医歯薬学総合研究科, 助教授
1999 – 2001: 長崎大学, 薬学部, 助教授
1997 – 1999: Kyoto University Graduate School of Pharmaceutical Sciences Instructor, 薬学研究科, 助手
1997: 京都大学, 大学院・薬学研究科, 助手
1995 – 1996: Kyoto University, Faculty of Pharmaceutical Sciences, Assistant Professor, 薬学部, 助手
1994: 京都大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Biological pharmacy / Medical pharmacy / Basic Section 47040:Pharmacology-related / Biological pharmacy
Except Principal Investigator
Biological pharmacy / Biological pharmacy / Clinical oncology / Biological Sciences
Keywords
Principal Investigator
ERK / インスリン受容体 / Akt / PI3 kinase / HDAC阻害剤 / がん / MEK阻害剤 / PI3キナーゼ / ERK-MAPキナーゼ / インスリン受容体関連受容体 … More / MNK / シグナル伝達 / ERK-MAP kinase / MEK inhibitor / lung cancer / Gefitinib / Sprouty / EGF receptor / PI3-kinase / 抗がん剤 / Bim / ERK1/2 / 活性酸素 / オーダーメード医療 / オルファン受容体 / 腎臓 / インスリン / キナーゼ阻害剤 / BRAF / Mnkキナーゼ / p38-MAPキナーゼ / 炎症 / ERK5 / NLRP3 / 脂肪細胞 / 糖尿病 / MNK1/2 / HDAC inhibitor / HDAC inhibitor / がん分子標的 / tyrosine kinase / MAP kinase / Ceramide / ドキソルビシン / ビンクリスチン / SPT / GCS / セラミド / ミトコンドリア / 活性酸素種 / Rb / ERK経路 / Thioredoxin / HDAC阻害 / アポトーシス / HDAC / vヒストン脱アセチル化酵素 / シグナル遮断剤 / がん分子標的療法 / ヒストン脱アセチル化酵素阻害剤 / フィードバック・インヒビター / FGF / MAPキナーゼ / Ras / β細胞 / オーファン受容体 / 膵臓 / バイオセンサー / ECL細胞 / 胃 / アゴニスト抗体 / 免疫染色 / 神経栄養因子 … More
Except Principal Investigator
FGF / gene / 受容体 / GEF-H1 / ERK-MAPキナーゼ / 細胞がん化 / 増殖因子 / リガンド / 細胞運動 / 中間径フィラメント / 細胞質分裂 / RhoA / c-Jun N-terminal Kinase / Matrix metalloproteinase / Sprouty / ERK-MAP kinase / p38MAPキナーゼ / lipid / adipose / cDNA / 遺伝子 / 脳 / 動物個体系 / HDAC阻害剤 / 併用療法 / HDAC 阻害剤 / 微小管重合阻害剤 / MEK阻害剤 / ERK-MAPキナーゼ経路 / がん化学療法 / Spindle Checkpoint / Cell Cycle / Intermediate Filaments / Cell Motility / Intracellular Localization / ERK-MAP Kinase / ケラチン8 / 細胞内局在性 / p90^<RSK> / スピンドルチェックポイント / スピンドルチェックポイト / 細胞周期制御 / c-Jun N-Terminal Kinase / 細胞内局在 / Cell cycle / GEH-H1 / Cytoskeletone / Regulation of cell function / p38 MAP kinase / MMP / NF-M / p27^<Kip1> / 細胞分化 / 細胞増殖 / 細胞質分裂制御 / 細胞周期動態 / GTP交換因子 / GDP / Negative Feedback Inhibitor / 中間系フィラメント / 細胞周期 / 細胞骨格系 / 細胞機能制御 / p38 MAPキナーゼ / Polyphenol / Molecular Target / Anti-inflammatory agent / Anti-tumor agent / Specific inhibitor / c-Jun N-terminal kinase / MAP kinase pathway / シグナル分子 / MAPキナーゼキナーゼ / MAPキナーゼ / フラボン / 特異的阻害剤 / ポリフェノール / 分子標的 / 抗炎症剤 / 抗がん剤 / 阻害剤 / JNK / MAPキナーゼカスケード / Neurotrophic Factor / Receptor / Ligand / Insulin / 神経栄養因子 / インスリン / growthfactor / 細胞増殖因子 / 上皮細胞 / 神経 / 脂肪組織 / growth factor / receptor / brain / 遺伝子発現 / ラット / FGF受容体 / 微小管阻害剤 / Bcl-2 ファミリー蛋白質 / MEK 阻害剤 / ERK-MAP キナーゼ経路 / Xenograft / チューブリン重合阻害剤 / Akt系 / PI3キナーゼ / ERK-MAPキナーゼ系 / 活性酸素種 / ERK-MAPキナーゼ路 / タンパク質 / 発現 Less
  • Research Projects

    (22 results)
  • Research Products

    (101 results)
  • Co-Researchers

    (19 People)
  •  Identification of downstream factors of the ERK-MAP kinase pathway as a putative target for treatment of signal transduction disorders.Principal Investigator

    • Principal Investigator
      Kei-ichi Ozaki
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47040:Pharmacology-related
    • Research Institution
      Doshisha Women's College of Liberal Arts
      Osaka University of Pharmaceutical Sciences
  •  Molecular mechanism for determinig the sensitivity of HDAC inhibitors in cancer cellsPrincipal Investigator

    • Principal Investigator
      Ozaki Kei-ichi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Osaka University of Pharmaceutical Sciences
      Nagasaki University
  •  Efficient cancer therapy by regulating ceramide metabolism in cancer cellsPrincipal Investigator

    • Principal Investigator
      OZAKI Keiichi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Nagasaki University
  •  Targeting the ERK-MAP kinase pathway in cancer therapy

    • Principal Investigator
      KOHNO Michiaki
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Clinical oncology
    • Research Institution
      Kyoto University
      Nagasaki University
  •  Basic research on personalized treatment of cancer by HDAC inhibitorsPrincipal Investigator

    • Principal Investigator
      OZAKI Kei-ichi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Nagasaki University
  •  Molecular targeted cancer therapy with HDAC inhibitorsPrincipal Investigator

    • Principal Investigator
      OZAKI Keiichi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Nagasaki University
  •  Targeting the ERK-MAP kinase pathway in cancer therapy

    • Principal Investigator
      KOHNO Michiaki
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Nagasaki University
  •  Role of MAP kinase cascades in the regulation of diverse cellular functions

    • Principal Investigator
      KOHNO Michiaki
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Nagasaki University
  •  Functional analysis of Sprouty-2 transcripts for determining the sensitivity to EGF-signaling inhibitors.Principal Investigator

    • Principal Investigator
      OZAKI Keiichi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Nagasaki University
  •  新規Rasインヒビターの細胞増殖制御メカニズムの解明と細胞癌化との関連についてPrincipal Investigator

    • Principal Investigator
      尾崎 恵一
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Nagasaki University
  •  Role of MAP Kinase Cascade in the Regulation of Diverse Cellular Functions

    • Principal Investigator
      KOHNO Michiaki
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Nagasaki University
  •  膵β細胞に見出された新規受容体IRRを介したシグナル伝達機構の解明Principal Investigator

    • Principal Investigator
      尾崎 惠一
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      Nagasaki University
  •  Development of specific inhibitors against MAP kinase pathways

    • Principal Investigator
      KOHNO Michiaki
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Nagasaki University
  •  受容体のギランド結合領域を用いた新しいリガンド探索法の開発

    • Principal Investigator
      伊藤 信行
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Biological pharmacy
    • Research Institution
      Kyoto University
  •  Elucidation of the role of FGF-10 in white adipose tissue

    • Principal Investigator
      ITOH Nobuyuki
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kyoto University
  •  新規なインスリン受容体関連受容体(IRR)の生理機能解明Principal Investigator

    • Principal Investigator
      尾崎 惠一 (尾崎 恵一)
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kyoto University
  •  受容体のリガンド結合領域を用いた新しいリガンド探索用プローブの開発

    • Principal Investigator
      ITOH Nobuyuki
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Biological pharmacy
    • Research Institution
      Kyoto University
  •  新規なインスリン受容体関連受容体の腎臓における生理的意義の解明Principal Investigator

    • Principal Investigator
      尾崎 惠一
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kyoto University
  •  elucidation on the roles of new FGFs

    • Principal Investigator
      ITOH Nobuyuki
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      KYOTO UNIVERSITY
  •  Identification of Novel Neurotrophic Factors

    • Principal Investigator
      ITOH Nobuyuki
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      KYOTO UNIVERSITY
  •  インスリンファミリーに属する新規の神経栄養因子の単離と構造解析Principal Investigator

    • Principal Investigator
      尾崎 恵一
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kyoto University
  •  Diversity of FGF receptor and their physiological significance

    • Principal Investigator
      ITOH Nobuyuki
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      KYOTO UNIVERSITY

All 2019 2018 2017 2013 2012 2011 2010 2009 2008 2007 2006 2005 2002 Other

All Journal Article Presentation Book

  • [Book] 細胞内シグナル伝達経路の選択的遮断を基盤としたがん治療戦略2008

    • Author(s)
      尾崎恵一、谷村進、河野通明
    • Publisher
      ファルマシア
    • Data Source
      KAKENHI-PROJECT-17016056
  • [Journal Article] Effect of cationic lipid in cationic liposomes on siRNA delivery into the lung by intravenous injection of cationic lipoplex.2019

    • Author(s)
      Hattori Y, Nakamura M, Takeuchi N, Tamaki K, Shimizu S, Yoshiike, Y, Taguchi M, Ohno H, Ozaki K, Onishi H.
    • Journal Title

      J. Drug Target.

      Volume: 27 Issue: 2 Pages: 217-227

    • DOI

      10.1080/1061186x.2018.1502775

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06694, KAKENHI-PROJECT-17K08251
  • [Journal Article] Effect of cationic lipid type in folate-PEG-modified cationic liposomes on folate receptor-mediated siRNA transfection in tumor cells2019

    • Author(s)
      Y.Hattori, N.Shimizu, K.Ozaki, H.Onishi.
    • Journal Title

      Pharmaceutics

      Volume: 11 Issue: 4 Pages: 181-181

    • DOI

      10.3390/pharmaceutics11040181

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06694
  • [Journal Article] Optimized combination of cationic lipids and neutral helper lipids in cationic liposomes for siRNA delivery into the lung by intravenous injection of siRNA lipoplexes.2019

    • Author(s)
      Hattori Y, Tamaki K, Ozaki K, Kawano K, Onishi H.
    • Journal Title

      J. Drug Deliv. Sci. Tec.

      Volume: 52 Pages: 1042-1050

    • DOI

      10.1016/j.jddst.2019.06.016

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06694, KAKENHI-PROJECT-17K08251
  • [Journal Article] Effect of cationic lipid type in PEGylated liposomes on siRNA delivery after intravenous injection of siRNA lipoplexes.2019

    • Author(s)
      Hattori Y, Nakamura M, Takeuchi N, Tamaki K, Ozaki K, Onishi H.
    • Journal Title

      Wrld. Acd. Sci.

      Volume: 1 Pages: 74-85

    • DOI

      10.3892/wasj.2019.8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06694
  • [Journal Article] Establishment of novel cells stably secreting various human IL-18 recombinant proteins.2019

    • Author(s)
      Asuka Kumagai, Kenji Shimizu, Riho Kurata, Xiaofeng Cui, Takayuki Isagawa, Msamitsu Harada, Jun Nagai, Yasuhiro Yoshida, Kei-ichi Ozaki, Norihiko Takeda, Hiroaki Semba and Tomo Yonezawa
    • Journal Title

      Current Pharmaceutical Biotechnology

      Volume: 20 Issue: 1 Pages: 47-55

    • DOI

      10.2174/1389201020666190206203640

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06895, KAKENHI-PROJECT-16K21229, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-18K06694, KAKENHI-PROJECT-18H02360
  • [Journal Article] New efforts for FD activity at Osaka University of Pharmaceutical Sciences2018

    • Author(s)
      Kurata R, Kumagai A, Cui X, Harada M, Nagai J, Yoshida Y, Ozaki K, Tanaka Y, Yonezawa T
    • Journal Title

      Japanese Journal of Pharmaceutical Education

      Volume: 2 Issue: 0 Pages: n/a

    • DOI

      10.24489/jjphe.2018-004

    • NAID

      130007493678

    • ISSN
      2432-4124, 2433-4774
    • Language
      Japanese
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06694
  • [Journal Article] Effect of cationic lipid type in cationic liposomes for siRNA delivery into the liver by sequential injection of chondroitin sulfate and cationic lipoplex2018

    • Author(s)
      Y. Hattori, N. Takeuchi, M. Nakamura, Y. Yoshiike, M. Taguchi, H. Ohno, K. Ozaki, H. Onishi,
    • Journal Title

      Journal of Drug Delivery Science and Technology

      Volume: 48 Pages: 235-244

    • DOI

      10.1016/j.jddst.2018.09.022

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08251, KAKENHI-PROJECT-18K06694
  • [Journal Article] Evaluation of in vitro and in vivo therapeutic anti-tumor efficacy of transduction of polo-like kinase 1 and heat shock transcription factor 1 small interfering RNA2017

    • Author(s)
      Y. Hattori, T. Kikuchi, K. Ozaki, H. Onishi
    • Journal Title

      Experimental and Therapeutic Medicine

      Volume: 14 Pages: 4300-4306

    • DOI

      10.3892/etm.2017.5060

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08251, KAKENHI-PROJECT-15K08075
  • [Journal Article] Effect of chondroitin sulfate on siRNA biodistribution and gene silencing effect in mice after injection of siRNA lipoplexes2017

    • Author(s)
      Y. Hattori, A. Nakamura, S. Hanaya, Y. Miyanabe, Y. Yoshiike, T. Kikuchi, K. Ozaki, H. Onishi
    • Journal Title

      Journal of Drug Delivery Science and Technology

      Volume: 41 Pages: 401-409

    • DOI

      10.1016/j.jddst.2017.08.012

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08251, KAKENHI-PROJECT-15K08075
  • [Journal Article] Therapeutic effects on liver- and lung-metastasized tumors of combination therapy with protein kinase N3 small interfering RNA and doxorubicin2017

    • Author(s)
      Hattori Y, Kikuchi T, Nakamura M, Ozaki K, Onishi H.
    • Journal Title

      Oncol. Lett.

      Volume: 14 Pages: 5157-5166

    • DOI

      10.3892/ol.2017.6830

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08075
  • [Journal Article] Blockade of the ERK pathway enhances the therapeutic efficacy of the histone deacetylase inhibitor MS-275 in human tumor xenograft models.2013

    • Author(s)
      Sakamoto, T.
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 433 Issue: 4 Pages: 456-462

    • DOI

      10.1016/j.bbrc.2013.03.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300340, KAKENHI-PROJECT-23790090, KAKENHI-PROJECT-24590197
  • [Journal Article] Blockade of the ERK pathway enhances the therapeutic efficacy of the histone deacetylase inhibitor MS-275 in human tumor xenograft models2013

    • Author(s)
      Sakamoto, T., Ozaki, K., Fujio, K., Kajikawa, S., Uesato, S., Watanabe, K., Tanimura, S., Koji, T. & Kohno, M
    • Journal Title

      Biochem. Biophys. Res. Commun

      Volume: 433 Pages: 456-462

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300340
  • [Journal Article] Targeting the extracellular signal-regulated kinase pathway in cancer therapy2011

    • Author(s)
      M. Kohno, S. Tanimura, and K. Ozaki
    • Journal Title

      Biol. Pharm. Bull

      Volume: 34 Pages: 1781-1784

    • Data Source
      KAKENHI-PROJECT-21590166
  • [Journal Article] Targeting the extracellular signal-regulated kinase pathway in cancer therapy.2011

    • Author(s)
      Kohno, M., Tanimura, S. & Ozaki, K.
    • Journal Title

      Biol. Pharm. Bull.

      Volume: 34 Pages: 1781-1784

    • NAID

      130001872595

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300340
  • [Journal Article] Targeting the Extracellular Signal-Regulated Kinase Pathway in Cancer Therapy2011

    • Author(s)
      Kohno M., Tanimura S., Ozaki K.
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 34 Issue: 12 Pages: 1781-1784

    • DOI

      10.1248/bpb.34.1781

    • NAID

      130001872595

    • ISSN
      0918-6158, 1347-5215
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590166, KAKENHI-PROJECT-22300340
  • [Journal Article] Blockade of the extracellularsignal-regulated kinase pathway enhances the therapeutic efficacy of microtubule destabilizing agents in human tumor xenograft models.2010

    • Author(s)
      Watanabe, K., Tanimura, S., Uchiyama, A., Sakamoto, T., Kawabata, T., Ozaki, K. & Kohno, M.
    • Journal Title

      Clin. Cancer Res

      Volume: 16 Pages: 1170-1178

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300340
  • [Journal Article] Blockade of the ERK or PI3K-Akt signaling pathway enhances the cytotoxicity of histone deacetylase inhibitors in tumor cells resistant to gefitinib or imatinib.2010

    • Author(s)
      Ozaki, K., Kosugi, M., Baba, N., Fujio, K., Sakamoto, T., Kimura, S., Tanimura, S., Kohno, M.
    • Journal Title

      Biochem. Biophys. Res. Commun. 391

      Pages: 1610-1615

    • NAID

      120006983583

    • Data Source
      KAKENHI-PROJECT-17016056
  • [Journal Article] Blockade of the ERK or PI3K-Akt pathway enhances the cytotoxicity of histone deacetylase inhibitors in tumor cells resistant to gefitinib or imatinib2010

    • Author(s)
      K. Ozaki, M. Kosugi, N. Baba, T. Sakamoto, K. Fujio, S. Kimura and M. Kohno
    • Journal Title

      Biochem. Biophys. Res. Commun

      Volume: 391 Pages: 1610-1615

    • Data Source
      KAKENHI-PROJECT-21590166
  • [Journal Article] Blockade of the ERK or PI3K-Akt signaling pathway enhances the cytotoxicity of histone deacetylase inhibitors in tumor cells resistant to gefitinib or imatinib.2010

    • Author(s)
      Ozaki, K.
    • Journal Title

      Biochem.Biophys.Res.Commun.

      Volume: 391 Pages: 1610-1615

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300340
  • [Journal Article] Blockade of the ERK or PI3K-Akt signaling pathway enhances the cytotoxicity of histone deacetylase inhibitors in tumor cells resistant to gefitinib or imatinib.2010

    • Author(s)
      Ozaki, K.
    • Journal Title

      Biochem.Biophys.Res.Commun. 391

      Pages: 1610-1615

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016056
  • [Journal Article] Blockade of the extracellular signal-regulated kinase pathway enhances the therapeutic efficacy of microtubuledestabilizing agents in human tumor xenograft models.2010

    • Author(s)
      Watanabe, K., Tanimura, S., Uchiyama, A., Sakamoto, T., Kawabata, T., Ozaki, K., Kohno, M.
    • Journal Title

      Clin. Cancer Res. 16

      Pages: 1170-1178

    • Data Source
      KAKENHI-PROJECT-17016056
  • [Journal Article] Blockade of the extracellular signal-regulated kinase pathway enhances the therapeutic efficacy of microtubule-destabilizing agents in human tumor xenograft models2010

    • Author(s)
      K. Watanabe, S. Tanimura, A. Uchiyama, T. Sakamoto, T. Kawabata, K. Ozaki, and M. Kohno
    • Journal Title

      Clin. Cancer Res

      Volume: 16 Pages: 1170-1178

    • Data Source
      KAKENHI-PROJECT-21590166
  • [Journal Article] Blockade of the ERK or PI3K-Akt signaling pathway enhances the cytotoxicity of histone deacetylase inhibitors in tumor cells resistant to gefitinib or imatinib.2010

    • Author(s)
      Ozaki, K., et al.
    • Journal Title

      Biochem. Biophys. Res.Commun. 391

      Pages: 1610-1615

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590166
  • [Journal Article] Blockade of constitutively activated ERK signaling enhances cytotoxicity of microtubule-destabilizing agents in tumor cells.2009

    • Author(s)
      Tanimura, S., Uchiyama, A., Watanabe, K., Yasunaga, M., Inada, Y., Kawabata, T., Iwashita, K., Noda, S., Ozaki, K., Kohno, M.
    • Journal Title

      Biochem. Biophys. Res. Commun. 378

      Pages: 650-655

    • NAID

      120006983970

    • Data Source
      KAKENHI-PROJECT-17016056
  • [Journal Article] Blockade of constitutively activated ERK signaling enhances cytotoxicity of microtubule-destabilizing agents in tumor cells2009

    • Author(s)
      S. Tanimura, A. Uchiyama, K. Watanabe, M. Yasunaga, T. Kawabata, K. Ozaki and M. Kohno
    • Journal Title

      Biochem. Biophys. Res. Commun

      Volume: 378 Pages: 650-655

    • Data Source
      KAKENHI-PROJECT-21590166
  • [Journal Article] Blockade of constitutively activated ERK signaling enhances cytotoxicity of microtubule-destabilizing agents in tumor cells2009

    • Author(s)
      S. Tanimura, A. Uchiyama, K. Watanabe, M. Yasunaga, Y. Inada, T. Kawabata, K. Iwashita, K. Ozaki and M. Kohno
    • Journal Title

      Biochem. Biophys. Res. Commun 378

      Pages: 650-655

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590148
  • [Journal Article] Histone deacetylase inhibitors enhance the chemosensitivity of tumor cells with cross-resistance to a wide range of DNA-damaging drugs.2008

    • Author(s)
      Ozaki, K., Kishikawa, F., Tanaka, M., Sakamoto, T., Tanimura, S, Kohno, M.
    • Journal Title

      Cancer Sci. 99

      Pages: 376-384

    • NAID

      10024002722

    • Data Source
      KAKENHI-PROJECT-17016056
  • [Journal Article] Histone deacetylase inhibitors enhance the chemosensitivity of tumor cells with cross-resistance to a wide range of DNA-damaging drugs.2008

    • Author(s)
      Ozaki, K.
    • Journal Title

      Cancer Sci. 99

      Pages: 376-384

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016056
  • [Journal Article] Histone deacetylase inhibitors enhance the chemosensitivity of tumor cells with cross-resistance to a wide range of DNA-damaging drugs2008

    • Author(s)
      Ozaki, K.
    • Journal Title

      Cancer Sci 99巻

      Pages: 376-384

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016056
  • [Journal Article] Histone deacetylase inhibitors enhance the chemosensitivity of tumor cells with cross-resistance to a wide range of DNA-damaging agents.2008

    • Author(s)
      Ozaki, K., et al.
    • Journal Title

      Cancer Sci. 99

      Pages: 376-384

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590148
  • [Journal Article] 細胞内シグナル伝達経路の選択的遮断を基盤としたがん治療戦略2008

    • Author(s)
      尾崎恵一, 他
    • Journal Title

      ファルマシア 44

      Pages: 219-224

    • Data Source
      KAKENHI-PROJECT-19590148
  • [Journal Article] 細胞内シグナル伝達経路の選択的遮断を基盤としたがん治療戦略2008

    • Author(s)
      尾崎恵一, 谷村進, 河野通明
    • Journal Title

      ファルマシア 44巻

      Pages: 219-224

    • Data Source
      KAKENHI-PROJECT-19590148
  • [Journal Article] Histone deacetylase inhibitors enhance the chemosensitivity of tumor cells with cross-resistance to a wide range of DNA-damaging agents2008

    • Author(s)
      K. Ozaki, F. Futaba, M. Tanaka, T. Sakamoto, S. Tanimura and M. Kohno
    • Journal Title

      Cancer Sci. 99

      Pages: 376-384

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590148
  • [Journal Article] Histone deacetylase inhibitors enhance the chemosensitivity of tumor cells with cross-resistance to a wide range of DNA-damaging agents2008

    • Author(s)
      Ozaki, K.
    • Journal Title

      Cancer Sci. 99

      Pages: 376-384

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590148
  • [Journal Article] Blockade of the phosphatidylinositol 3-kinase-Akt signaling pathway enhances induction of apoptosis by microtubule-destabilizing agents in tumor cells in which the pathway is constitutively activated.2007

    • Author(s)
      Fujiwara, Y., Hosokawa, Y., Watanabe, K., Tanimura, S., Ozaki, K., Kohno, M.
    • Journal Title

      Mol.Cancer Ther. 6

      Pages: 1133-1142

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390020
  • [Journal Article] Blockade of the phosphatidylinositol-3-kinase Akt signaling pathway enhances induction of apoptosis by microtubule-destabilizing agents in tumor cells in which the pathway is constitutively activated2007

    • Author(s)
      Y. Fujiwara, Y. Hosokawa, K. Watanabe, S. Tanimura, K. Ozaki and M. Kohno
    • Journal Title

      Mol. Cancer Ther 6

      Pages: 1133-1142

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590148
  • [Journal Article] Targeted molecular strategies for cancer therapy based on the blockade of oncogenic pathways in human tumor cells2007

    • Author(s)
      K. Ozaki
    • Journal Title

      J. Pharm. Soc.Japan 127

      Pages: 983-991

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590148
  • [Journal Article] Targeted molecular strategies for cancer therapy based on the blockade of oncogenic pathways in human tumor cells2007

    • Author(s)
      Ozaki, K.
    • Journal Title

      Yakugaku Zasshi 127

      Pages: 983-991

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590148
  • [Journal Article] Anticancerdrugs upregulate HspBP1 and therby antagonize the prosurvival function of Hsp70 in tumor cells2007

    • Author(s)
      S. Tanimura, A. Hirano, J. Hashizume, M. Yasunaga, T. Kawabata, K. Ozaki and M. Kohno
    • Journal Title

      J. Biol. Chem 282

      Pages: 35430-35439

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590148
  • [Journal Article] Blockade of the phosphatidylinositol 3-kinase-Akt signaling pathway enhances induction of apoptosis by microtubuledestabilizing agents in tumor cells in which the pathway is constitutively activated.2007

    • Author(s)
      Fujiwara, Y., Hosokawa, Y., Watanabe, K., Tanimura, S., Ozaki, K, Kohno, M.
    • Journal Title

      Mol. Cancer Ther. 6

      Pages: 1133-1142

    • Data Source
      KAKENHI-PROJECT-17016056
  • [Journal Article] Anticancer drugs up-regulate HspBP1 and thereby antagonize the prosurvival function of Hsp70 in tumor cells.2007

    • Author(s)
      Tanimura, S., Hirano, A., Hashizume, J., Yasunaga, M., Kawabata, T., Ozaki, K, Kohno, M.
    • Journal Title

      J. Biol. Chem. 282

      Pages: 35430-35439

    • Data Source
      KAKENHI-PROJECT-17016056
  • [Journal Article] Blockade of the ERK pathway markedly sensitizes tumor cells to HDAC inhibitor-induced cell death.2006

    • Author(s)
      Ozaki, K.
    • Journal Title

      Biochem.Biophys.Res.Commun. 339巻

      Pages: 1171-1177

    • Data Source
      KAKENHI-PROJECT-17390020
  • [Journal Article] Blockade of the ERK pathway markedly sensitizes tumor cells to HDAC inhibitor-induced cell death.2006

    • Author(s)
      Ozaki, K.
    • Journal Title

      Biochem.Biophys.Res.Commun. 339巻

      Pages: 1171-1177

    • Data Source
      KAKENHI-PROJECT-17016056
  • [Journal Article] Blockade of the ERK pathway markedly sensitizes tumor cells to HDAC inhibitor-induced cell death.2006

    • Author(s)
      Ozaki, K., Minoda, A., Kishikawa, F, Kohno, M.
    • Journal Title

      Biochem. Biophys. Res. Commun. 339

      Pages: 1171-1177

    • Data Source
      KAKENHI-PROJECT-17016056
  • [Journal Article] Blockade of the ERK pathway markedly sensitizes tumor cells to HDAC inhibitor-induced cell death.2006

    • Author(s)
      Ozaki, K.
    • Journal Title

      Biochem. Biophys. Res. Commun. 339巻

      Pages: 1171-1177

    • Data Source
      KAKENHI-PROJECT-17016056
  • [Journal Article] Blockade of the ERK pathway markedly sensitizes tumor cells to HDAC inhibitor-induced cell death.2006

    • Author(s)
      Ozaki, K. et al.
    • Journal Title

      Biochem. Biophys. Res. Commun. 339 (4)

      Pages: 1171-1177

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590052
  • [Journal Article] Inhibition of the PI3 kinase/Akt pathway enhances doxorubicin-induced apoptotic cell death in tumor cells in a p53-dependent manner.2006

    • Author(s)
      Fujiwara, Y., Kawada, K., Takano, D., Tanimura, S., Ozaki, K., Kohno, M.
    • Journal Title

      Biochem.Biophys.Res.Commun. 340

      Pages: 560-566

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390020
  • [Journal Article] Blockade of the ERK pathway markedly sensitizes tumor cells to HDAC inhibitor-induced cell death.2006

    • Author(s)
      Ozaki, K., Minoda, A., Kishikawa, F., Kohno, M.
    • Journal Title

      Biochem.Biophys.Res.Commun. 339

      Pages: 1171-1177

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390020
  • [Journal Article] Blockade of the ERK pathway markedly sensitizes tumor cells to HDAC inhibitor-induced cell death.2006

    • Author(s)
      Ozaki, K. et al.
    • Journal Title

      Biochem. Biophys. Res. Commun. 339(4)

      Pages: 1171-1177

    • Data Source
      KAKENHI-PROJECT-16590052
  • [Journal Article] Blockade of the ERK pathway markedly sensitizes tumor cells to HDAC inhibitor-induced cell death.2006

    • Author(s)
      Ozaki, K.
    • Journal Title

      Biochem. Biophys. Res. Commun. 339巻

      Pages: 1171-1177

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390020
  • [Journal Article] Blockade of the ERK pathway markedly sensitizes tumor cells to HDAC inhibitor-induced cell death.2006

    • Author(s)
      K, Ozaki et al.
    • Journal Title

      Biochem.Biophys.Res.Commun. 339(4)

      Pages: 1171-1177

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590052
  • [Journal Article] Hetero-oligomerization of mammalian Sprouty1 and Sprouty4 efficiently suppresses fibroblast growth fabcor-2-induced ERK activation by preventing the association of Grb2-SOS1 complex with FRS2.2005

    • Author(s)
      Ozaki, K.
    • Journal Title

      J.Biol.Chem. 280巻(印刷中)

    • Data Source
      KAKENHI-PROJECT-14370747
  • [Journal Article] Efficient suppression of FGF-2-induced ERK activation by the cooperative interaction among mammalian Sprouty isoforms.2005

    • Author(s)
      K, Ozaki et al.
    • Journal Title

      J.Cell Sci. 118(24)

      Pages: 5861-5871

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590052
  • [Journal Article] Hetero-oligomerization of mammalian Sprouty1 and Sprouty4 efficiently suppresses fibroblast growth factor-2-induced ERK activation by preventing the association of Grb2-Sos1 complex with FRS2.2005

    • Author(s)
      Ozaki, K., Miyazaki, S., Tanimura, S., Kohno, M.
    • Journal Title

      Oncogene (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370747
  • [Journal Article] Efficient suppression of Fibroblast Growth Factor-2-induced ERK activation by the cooperative interaction among mammalian Sprouty isoforms.2005

    • Author(s)
      Ozaki, K.
    • Journal Title

      J.Cell Sci. 118巻

      Pages: 5861-5871

    • Data Source
      KAKENHI-PROJECT-17016056
  • [Journal Article] Efficient Suppression of Fibroblast Growth Factor-2-induced ERK Activation by the Cooperative Interaction among Mammalian Sprouty Isoforms.2005

    • Author(s)
      Ozaki, K., Miyazaki, S., Tanimura, S, Kohno, M.
    • Journal Title

      J. Cell Sci. 118

      Pages: 5861-5871

    • Data Source
      KAKENHI-PROJECT-17016056
  • [Journal Article] Efficient suppression of Fibroblast Growth Factor-2-induced ERK activation by the cooperative interaction among mammalian Sprouty isoforms.2005

    • Author(s)
      Ozaki, K.
    • Journal Title

      J. Cell Sci. 118巻

      Pages: 5861-5871

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390020
  • [Journal Article] Efficient suppression of FGF-2-induced ERK activation by the cooperative interaction among mammalian Sprouty isoforms.2005

    • Author(s)
      Ozaki, K. et al.
    • Journal Title

      J. Cell Sci. 118 (24)

      Pages: 5861-5871

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590052
  • [Journal Article] Efficient Suppression of Fibroblast Growth Factor-2-induced ERK Activation by the Cooperative Interaction among Mammalian Sprouty Isoforms.2005

    • Author(s)
      Ozaki, K., Miyazaki, S., Tanimura, S., Kohno, M.
    • Journal Title

      J.Cell Sci. 118

      Pages: 5861-5871

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390020
  • [Journal Article] Efficient suppression of FGF-2-induced ERK activation by the cooperative interaction among mammalian Sprouty isoforms.2005

    • Author(s)
      Ozaki, K. et al.
    • Journal Title

      J. Cell Sci. 118(24)

      Pages: 5861-5871

    • Data Source
      KAKENHI-PROJECT-16590052
  • [Journal Article] Prolonged Nuclear Retention of Activated Extracellular Signal-Regulated Kinase1/2 is Required for Hepatocyte Growth Factor-induced Cell Motility.2002

    • Author(s)
      Tanimura, S., Nomura, K., Ozaki, K., Tsujimoto, M., Kondo, T., Kohno, M.
    • Journal Title

      J.Biol.Chem. 277

      Pages: 28256-28264

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370747
  • [Journal Article] Anticancer drugs up-regulate HspBP1 and thereby antagonize the prosurvival function of Hsp70 in tumor cells.

    • Author(s)
      Tanimura, S., Hirano, A., Hashizume, J., Tasunaga, M., Kawabata, T., Ozaki, K., Kohno, M.
    • Journal Title

      J.Biol.Chem. (under review)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390020
  • [Presentation] The effects of combination therapy by MEK and HDAC inhibitor in mouse mammary cancer cells.2019

    • Author(s)
      T.Shima, K.Taniguchi, K.Ozaki, M.Shibata, K.Uchiyama.
    • Organizer
      第78回 日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K06694
  • [Presentation] Myosin1E によるカベオラ形成制御と細胞運動2012

    • Author(s)
      中原康子、 谷村 進、浜松絢子、尾崎惠一、武田弘資、河野通明
    • Organizer
      第29回日本薬学会九州支部大会
    • Place of Presentation
      熊本県
    • Year and Date
      2012-12-09
    • Data Source
      KAKENHI-PROJECT-22300340
  • [Presentation] Myosin1E の細胞運動亢進作用はUNC45-Hsp90 複合体による細胞内局在制御によって調節される2012

    • Author(s)
      谷村 進、 平田弦也、大山 要、中原康子、松丸由美、尾崎惠一、武田弘資、河野通明
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡県
    • Year and Date
      2012-12-15
    • Data Source
      KAKENHI-PROJECT-22300340
  • [Presentation] UNC45 によるMyosin1E の細胞内局在制御2012

    • Author(s)
      平田弦也、 谷村 進、木原康孝、 尾崎惠一、武田弘資、 河野通明
    • Organizer
      第29回日本薬学会九州支部大会
    • Place of Presentation
      熊本県
    • Year and Date
      2012-12-09
    • Data Source
      KAKENHI-PROJECT-22300340
  • [Presentation] HC-toxinとPD184352の併用はBimの発現上昇を介してROSの蓄積と細胞死を相乗的に誘導する2011

    • Author(s)
      尾崎恵一、河野通明, 他
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県)
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-22300340
  • [Presentation] HC-toxin and PD184352 synergistically up-regulate Bim and TBP-2 to induce the enhanced ROS accumulation and cell death2011

    • Author(s)
      K, Ozaki, K, Fujio, T, Sakamoto, S, Kajikawa, and M, Kohno
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-21590166
  • [Presentation] ERK経路の活性化及びp53遺伝子型とHDAC阻害剤感受性の相関2011

    • Author(s)
      梶川修平、坂元利彰、尾崎惠一
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2011-12-14
    • Data Source
      KAKENHI-PROJECT-21590166
  • [Presentation] ERK経路の活性化及びp53遺伝子型とHDAC阻害剤感受性の相関2011

    • Author(s)
      梶川修平, 坂元利彰, 尾崎惠一, 河野通明
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-21590166
  • [Presentation] HC-toxin and PD184352 synergistically up-regulate Bim and TBP-2 to induce the enhanced ROS accumulation and cell death2011

    • Author(s)
      尾崎惠一、藤尾康祐、河野通明
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(名古屋)
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-21590166
  • [Presentation] HDAC阻害剤とMEK阻害剤の併用による細胞死誘導増強-FOXO転写因子ファミリーの役割2010

    • Author(s)
      藤尾康祐, 梶川修平, 坂元利彰, 尾崎惠一, 河野通明
    • Organizer
      第27回日本薬学会九州支部大会
    • Place of Presentation
      長崎
    • Data Source
      KAKENHI-PROJECT-21590166
  • [Presentation] HDAC阻害剤とMEK阻害剤の併用による細胞死誘導増強-FOXO転写因子ファミリーの役割-2010

    • Author(s)
      藤尾康祐, 梶川修平, 坂元利彰, 尾崎恵一, 河野通明
    • Organizer
      第27回日本薬学会九州支部大会
    • Place of Presentation
      長崎
    • Year and Date
      2010-12-11
    • Data Source
      KAKENHI-PROJECT-21590166
  • [Presentation] がん細胞におけるERK経路活性化とHDAC阻害剤感受性の相関2010

    • Author(s)
      梶川修平, 坂元利彰, 藤尾康祐, 尾崎惠一, 河野通明
    • Organizer
      第9回次世代を担う若手ファーマ・バイオフォーラム2010
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-21590166
  • [Presentation] PI3キナーゼ-Akt経路遮断剤は細胞内セラミド量を増大させることにより微小管重合阻害剤の感受性を増強する2010

    • Author(s)
      尾崎恵一
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-22300340
  • [Presentation] Blockade of the ERK pathway enhances the therapeutic efficacy of HDAC inhibitors in human tumor xenograft models2010

    • Author(s)
      T. Sakamoto, K. Fujio, S. Kajikawa, S. Uesato, K. Watanabe, S. Tanimura, K. Ozaki, M. Kohno
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-21590166
  • [Presentation] MEK阻害剤とHDAC阻害剤の併用による抗腫瘍効果増強-Xenograftでの検討-2010

    • Author(s)
      坂元利彰、藤尾康祐、梶川修平、上里新一、渡邉一石、 谷村 進、 尾崎恵一、河野通明
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪府
    • Year and Date
      2010-09-23
    • Data Source
      KAKENHI-PROJECT-22300340
  • [Presentation] Blockade of the ERK pathway enhances the therapeutic efficacy of HDAC inhibitors in human tumor xenograft models.2010

    • Author(s)
      坂元利彰, 藤尾康祐, 梶川修平, 上里新一, 尾崎恵一, 河野通明
    • Organizer
      第68回日本癌学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-21590166
  • [Presentation] PI3キナーゼ/Akt経路遮断はセラミド蓄積を増大させることでドキソルビシンの細胞障害作用を増強する2009

    • Author(s)
      尾崎恵一
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-01
    • Data Source
      KAKENHI-PROJECT-17016056
  • [Presentation] HDAC阻害剤とMEK阻害剤の併用による細胞死増強の分子機構2009

    • Author(s)
      坂元利彰、尾崎恵一, 他
    • Organizer
      日本アポトーシス研究会
    • Place of Presentation
      長崎
    • Year and Date
      2009-08-02
    • Data Source
      KAKENHI-PROJECT-21590166
  • [Presentation] MEK阻害剤とHDAC阻害剤の併用による抗腫瘍効果増強-xenograftでの検討2009

    • Author(s)
      坂元利彰, 藤尾康祐, 梶川修平, 尾崎惠一, 河野通明
    • Organizer
      第26回日本薬学会九州支部大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-21590166
  • [Presentation] HDAC阻害剤とMEK阻害剤の併用による細胞死増強の分子機構2009

    • Author(s)
      坂元利彰, 尾崎惠一, 馬場伸幸, 藤尾康祐, 梶川修平, 河野通明
    • Organizer
      第18回日本アポトーシス研究会学術集会
    • Place of Presentation
      長崎
    • Data Source
      KAKENHI-PROJECT-21590166
  • [Presentation] イマチニブ抵抗性Bcr-Abl変異(T315I)白血病細胞に対する効果的治療法の開発2009

    • Author(s)
      馬場伸幸, 尾崎惠一, 河野通明
    • Organizer
      第26回日本薬学会九州支部大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-21590166
  • [Presentation] Blockade of constitutively activated ERK signaling enhances cytotoxicity of HDAC inhibitors in tumor cells2009

    • Author(s)
      T. Sakamoto, K. Ozaki, N. Baba, K. Fujio, S. Tanimura, M. Kohno
    • Organizer
      The Second Asian Symposium on Pharmaceutical Sciences in Nagasaki
    • Place of Presentation
      長崎
    • Data Source
      KAKENHI-PROJECT-19590148
  • [Presentation] Molecular mechanisim via which solid tumors become chemoresistant under hypoxic conditions2008

    • Author(s)
      尾崎恵一, 田中将人, 河野通明
    • Organizer
      第67回日本癌学会総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-19590148
  • [Presentation] Molecular mechanism for the enhanced cell death induced by the combination of HDAC inhibitors and MEK inhibitors2008

    • Author(s)
      坂元利彰, 尾崎恵一, 河野通明
    • Organizer
      第67回日本癌学会総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-19590148
  • [Presentation] 低酸素環境下における癌細胞の抗癌剤耐性獲得の分子機構2008

    • Author(s)
      尾崎恵一
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-29
    • Data Source
      KAKENHI-PROJECT-17016056
  • [Presentation] PI3キナーゼ/Akt経路遮断剤とドキソルビシの併用による細胞死誘導増強 : セラミドの関与2008

    • Author(s)
      積佳江, 尾崎惠一, 坂野 喜子, 河野通明
    • Organizer
      Biochemistry and Molecular Biology 2008
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-19590148
  • [Presentation] Targeting the ERK signaling pathway in cancer therapy2007

    • Author(s)
      河野通明、谷村進、尾崎惠一、渡邊一石
    • Organizer
      第65回日本癌学会総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-17016056
  • [Presentation] 低酸素環境下における癌細胞の抗癌剤耐性獲の分子機構2007

    • Author(s)
      田中将人, 尾崎惠一, 河野通明
    • Organizer
      第24回日本薬学会九州支部大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-19590148
  • [Presentation] Blockade of the PI3K-Akt pathway selectively enhances induction of apoptosis by microtubule-destabilizing agents2007

    • Author(s)
      藤原雄介, 渡邊一石, 谷村進, 尾崎惠一, 河野通明
    • Organizer
      第66回日本癌学会総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19590148
  • [Presentation] HDAC阻害剤とMEK阻害剤の併用による細胞死誘導の分子機構2007

    • Author(s)
      尾崎 恵一
    • Organizer
      第24回 日本薬学会九州支部大会
    • Place of Presentation
      福岡
    • Year and Date
      2007-12-08
    • Data Source
      KAKENHI-PROJECT-19590148
  • [Presentation] HDAC阻害剤とMEK阻害剤の併用による細胞死誘導の分子機構2007

    • Author(s)
      坂元利彰, 馬場伸幸, 尾崎惠一, 河野通明
    • Organizer
      第24回日本薬学会九州支部大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-19590148
  • [Presentation] Blockade of the PI3-kinase-Akt signaling pathway enhances induction of apoptosis by microtubule- destabilizing agents in tumor cells in which the pathway is constitutively activated.2007

    • Author(s)
      Watanabe, K., Fujiwara, Y., Tanimura, S., Ozaki, K, Kohno, M.
    • Organizer
      AACR Annual Meeting 2007
    • Place of Presentation
      Los Angeles
    • Data Source
      KAKENHI-PROJECT-17016056
  • [Presentation] PI3キナーゼ/Akt経路遮断剤とドキソルビシの併用による細胞死誘導増強-セラミドの関与2007

    • Author(s)
      積佳江, 尾崎惠一, 河野通明
    • Organizer
      第24回日本薬学会九州支部大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-19590148
  • [Presentation] Effective chemotherapeutic strategies for the treatment of lung adenocarcinoma cells harboring EGFR mutation2007

    • Author(s)
      尾崎惠一, 小杉正生, 坂元利彰, 河野通明
    • Organizer
      第66回日本癌学会総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19590148
  • [Presentation] Targeting the ERK signaling pathway in cancer therapy2007

    • Author(s)
      河野通明, 谷村進, 尾崎惠一
    • Organizer
      第66回日本癌学会総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19590148
  • [Presentation] Effective chemotherapeutic strategies for the treatment of lung adenocarcinoma cells harboring EGFR mutation2007

    • Author(s)
      尾崎 恵一
    • Organizer
      第65回 日本癌学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-05
    • Data Source
      KAKENHI-PROJECT-19590148
  • [Presentation] 非小細胞肺がん細胞株に対するペメトレキシドとシスプラチンとの併用効果

    • Author(s)
      尾崎惠一、村山裕一、川崎量子
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌市
    • Data Source
      KAKENHI-PROJECT-24590197
  • [Presentation] MEK阻害剤によるがん細胞のHDAC阻害剤感受性増強の分子機構

    • Author(s)
      尾崎惠一、川崎亮平、河野通明
    • Organizer
      第16回日本がん分子標的治療学会学術集会
    • Place of Presentation
      北九州市
    • Data Source
      KAKENHI-PROJECT-24590197
  • 1.  ITOH Nobuyuki (10110610)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 2.  KOHNO Michiaki (00027335)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 26 results
  • 3.  TANIMURA Susumu (90343342)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 23 results
  • 4.  UESATO Shin-ichi (50111969)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 5.  OHUCHI Hideyo (00253229)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  MATSUMURA Yoshihiro (60026309)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  KOUNO Isao (20038607)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  星野 理香 (60315265)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  武田 弘資 (10313230)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  福永 理己郎 (40189965)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  OHTA Mitsuhiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  FUJIMOTO Masafumi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  KAKIMOTO Takako
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  坂元 利彰
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 15.  藤尾 康祐
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 16.  梶川 修平
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 17.  YONEZAWA Tomo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  服部 喜之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 19.  倉田 里穂
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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