Tsumaki Noriyuki 妻木範行

… Alternative Names

TSUMAKI Noriyuki 妻木範行

妻木範行ツマキノリユキ

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Researcher Number	50303938
Other IDs
External Links
Affiliation (Current)	2025: 大阪大学, 大学院生命機能研究科, 教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 大阪大学, 大学院生命機能研究科, 教授 2011 – 2021: 京都大学, iPS細胞研究所, 教授 2016: 京都大学, その他部局等, 教授 2010: 大阪大学, 大学院・医学系研究科, 独立准教授 2007 – 2010: Osaka University, Graduate School of Medicine, Associate Professor 2003 – 2006: 大阪大学, 医学系研究科, 助手 1999: 阪大, 医学部, 助手
Review Section/Research Field	Principal Investigator Orthopaedic surgery / Basic Section 56020:Orthopedics-related / Orthopaedic surgery Except Principal Investigator Orthopaedic surgery / Basic Section 52050:Embryonic medicine and pediatrics-related
Keywords	Principal Investigator 軟骨 / 細胞分化 / 軟骨細胞 / 内軟骨性骨化 / iPS細胞 / ノックアウトマウス / コラーゲン / トランスジェニックマウス / 動物モデル / SIK3 … More / 椎間板 / 関節軟骨 / 遺伝子改変マウス / 分化 / collagen / 転写制御 / 骨形成 / 関節 / 骨形成因子 / 網羅的遺伝子発現解析 / ゼノグラフト / 疾患モデル / 骨系統疾患 / メタボローム / 代謝 / 再生 / 骨欠損 / 髄核 / 軟骨細胞分化 / 再生治療 / シングルセルRNAシーケンス / 霊長類動物モデル / 髄核細胞 / 骨格形成 / 椎間板髄核 / ＳＩＫ３ / Sox9 / コンディショナルノックアウトマウス / gene / joint / animal model / Bone morphogenetic proteins / 転写因子 / 骨 / 遺伝子 / Col11a2 / knockout mice / dedifferentiation / cartilage / regeneration / SIK / differentiation / iPS cells / Cyp26b1 / chondrocyte / HDAC4 / 初期化因子 / 軟骨発生 / 新生骨 / 骨強度 / 骨伝導 … More Except Principal Investigator E2F / NFkB / 分化誘導 / 軟骨細胞 / 変形性関節症 / 骨芽細胞 / 関節軟骨 / 再生医療 / 人工骨 / 骨再生 / 薬剤開発 / 遺伝子診断 / モデルマウス / iPS細胞 / 骨折 / 骨系統疾患 / 成長軟骨帯 / 成長 / 骨石灰化 / ノックインマウス / 脆弱性骨折 / 疾患特異的iPS細胞 / 骨脆弱性 / 骨形成不全症 / siRNA ライブラリー / 低分子化合物ライブラリー / 再分化 / 脱分化 / 低分子化合物 / 椎間板穿刺モデル / AP-1阻害剤 / 脊椎脊髄病学 / トランスジェニックマウス / 腰椎椎間板 / CILP / transcription factor / lung metastasis / osteosarcoma / osteoarthritis / arthritis / therapy with nucleic acid / 破骨細胞 / デコイ型核酸医薬 / 転写因子 / 肺転移 / 骨肉腫 / 関節炎 / 核酸医薬 / hydroxyapatite / tissue engineering / osteoblast / mesenchymal stem cell / bone substitute / bone regeneration / ハイドロキシアパタイト / 骨髄幹細胞 / シグナル伝達 / 再生医学 / 老化 / p53 isoforms / 軟骨分化 / 間葉系幹細胞 / 軟骨細胞分化 / p53 isoform / p53 / 細胞老化 / 潤滑機能 / マイクロアレイ / 関節表層 / メカニカルストレス / PRG4 / 遺伝子改変マウス / 関節表層遺伝子 / メカノセンシング / Prg4 / ルブリシン / 幹細胞 / 骨形成因子 Less

シングルセル網羅的発現解析とiPS細胞モデルによるヒト軟骨分化機構の解明Principal Investigator
- Principal Investigator
  
  妻木範行
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Osaka University
Analysis of regulatory mechanisms for differentiation of human cartilage tissuePrincipal Investigator
- Principal Investigator
  
  Tsumaki Noriyuki
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Osaka University
  Kyoto University
Analysis of mechanism of bone fragility and effects of drugs in osteogenesis imperfecta using a graft model for enchondral bone formation
- Principal Investigator
  
  Ozono Keiichi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Osaka University
Analysis of regulation of chondrocyte differentiation by SIK3 and lipid metabolismPrincipal Investigator
- Principal Investigator
  
  Tsumaki Noriyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyoto University
Screening of small compounds and factors to re-differentiate dedifferentiated chondrocytes in 2D culture
- Principal Investigator
  
  FUJITA KAORI
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyoto University
Analysis of mechanism for chondrocyte differentiation and maintenance that overcome cell aging
- Principal Investigator
  
  FUJITA Kaori
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyoto University
Establishment of the treatment and pathophysiology based on the suppression of the intervertebral disc degeneration .
- Principal Investigator
  
  Seki Shoji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  University of Toyama
Investigation of molecular and mechanosensitive mechanisms on lubricin-targeted gene expression specific to the surface of joint
- Principal Investigator
  
  YAMAMOTO KOJI
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyoto University
Analysis of regulatory mechanisms controlling proliferation and differentiation of chondrocytesPrincipal Investigator
- Principal Investigator
  
  Tsumaki Noriyuki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyoto University
Analysis of BMP-mediated cartilage formation anddifferentiation, and cartilage repairPrincipal Investigator
- Principal Investigator
  
  TSUMAKI Noriyuki
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyoto University
  Osaka University
Development of highly functional bone substitutes for bone regeneration
- Principal Investigator
  
  YOSHIKAWA Hideki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Osaka University
脂肪細胞から核の初期化を経て誘導した軟骨細胞による軟骨修復Principal Investigator
- Principal Investigator
  
  妻木範行
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Osaka University
Analysis of cartilage formation and differentiation through regulation of chondrocyte signaling and transcription of matrix genesPrincipal Investigator
- Principal Investigator
  
  TSUMAKI Noriyuki
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Osaka University
超音波刺激,人工骨,骨形成因子(BMP)シグナル操作を組み合わせた骨欠損の修復Principal Investigator
- Principal Investigator
  
  妻木範行
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Osaka University
Development of new strategy focusing on transcription factor as the therapeutic target for intractable bone and joint disease
- Principal Investigator
  
  TOMITA Tetsuya
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Osaka University
Development of Novel Hybrid Bone Substitute with Stem cells and Growth Factors
- Principal Investigator
  
  YOSHIKAWA Hideki
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Osaka University
Analysis transcriptional regulation of cartilage genesPrincipal Investigator
- Principal Investigator
  
  TSUMAKI Noriyuki
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Osaka University
軟骨コラーゲン遺伝子の転写制御メカニズムの解析Principal Investigator
- Principal Investigator
  
  妻木範行
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Osaka University

[Book] 日本整形外科学会雑誌2024
- Author(s)
  阿部健吾妻木範行
- Total Pages
  6
- Publisher
  日本整形外科学会
- Data Source
  KAKENHI-PROJECT-23K27720
[Book] 実践医学増刊「オルガノイドがもたらすライフサイエンス革命」2024
- Author(s)
  妻木　範行
- Total Pages
  8
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-23K27720
[Book] 「臨床整形外科」2024
- Author(s)
  妻木　範行
- Total Pages
  8
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-23K27720
[Book] 標準整形外科学　第15版2023
- Author(s)
  妻木　範行
- Total Pages
  6
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-23K27720
[Book] 標準整形外科学第15版2023
- Author(s)
  妻木　範行
- Total Pages
  6
- Publisher
  医学書院　（2023年2月発行）第7章
- Data Source
  KAKENHI-PROJECT-18H02923
[Book] 学術定期雑誌「HORMONE　FRONTIER　IN　GYNECOLOGY」第117号2023
- Author(s)
  妻木　範行
- Total Pages
  6
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-23K27720
[Book] 「生体の科学」2023
- Author(s)
  妻木　範行
- Total Pages
  6
- Publisher
  金原一郎記念医学医療振興財団
- Data Source
  KAKENHI-PROJECT-23K27720
[Book] 最新の骨粗鬆症学（第2版）2023
- Author(s)
  妻木　範行
- Total Pages
  6
- Publisher
  日本臨牀 81 巻増刊号1 (2023 年1 月発行)
- Data Source
  KAKENHI-PROJECT-18H02923
[Book] 「Precision Medicine」変形性関節症：病態研究と治療の最前線2023
- Author(s)
  妻木　範行
- Total Pages
  5
- Publisher
  北隆館
- Data Source
  KAKENHI-PROJECT-23K27720
[Book] 最新関節リウマチ学(第 2 版) 寛解・治癒を目指した研究と最新治療2023
- Author(s)
  妻木　範行
- Total Pages
  7
- Publisher
  日本臨牀
- Data Source
  KAKENHI-PROJECT-23K27720
[Book] 宝函2023
- Author(s)
  妻木　範行
- Total Pages
  8
- Publisher
  学術誌SRL
- Data Source
  KAKENHI-PROJECT-23K27720
[Book] 学術定期雑誌『HORMONE FRONTIER IN GYNECOLOGY』第 117 号（Vol.30 No.1，2023 年 3 月号）2023
- Author(s)
  妻木　範行
- Total Pages
  6
- Publisher
  株式会社メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-18H02923
[Book] 「整形・災害外科」新しい医療技術2023
- Author(s)
  海渡貴司妻木範行
- Total Pages
  5
- Publisher
  金原出版
- Data Source
  KAKENHI-PROJECT-23K27720
[Book] 創立100周年記念特別企画～バイオテクノロジーが拓く未来社会～　特集　iPS細胞の医療応用に向けた開発最前線2022
- Author(s)
  妻木　範行・島　伸行
- Total Pages
  4
- Publisher
  生物工学会誌　2022 年 100 巻 12 号
- Data Source
  KAKENHI-PROJECT-18H02923
[Book] ファルマシア2022
- Author(s)
  妻木　範行
- Total Pages
  1
- Publisher
  日本薬学会
- Data Source
  KAKENHI-PROJECT-18H02923
[Book] 最新関節リウマチ学(第 2 版) 寛解・治癒を目指した研究と最新治療2022
- Author(s)
  妻木　範行
- Total Pages
  8
- Publisher
  日本臨牀　80 巻増刊号 4 (2022 年 4 月 30 日発行) 別刷
- Data Source
  KAKENHI-PROJECT-18H02923
[Book] 別冊「医学のあゆみ」再生医療はどこまで進んだか2021
- Author(s)
  妻木　範行
- Total Pages
  5
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-18H02923
[Book] 今日の整形外科治療指針2021
- Author(s)
  妻木　範行
- Total Pages
  3
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-18H02923
[Book] 骨軟骨筋科学Update20212021
- Author(s)
  妻木　範行
- Total Pages
  1
- Publisher
  日本骨代謝学会刊行雑誌
- Data Source
  KAKENHI-PROJECT-18H02923
[Book] THE BONE Vol.33 No.12019
- Author(s)
  妻木範行
- Total Pages
  5
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-18H02923
[Book] 臨床整形外科Vol.54 No.102019
- Author(s)
  妻木範行
- Total Pages
  4
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-18H02923
[Book] 日本整形外科学会雑誌第93巻第12号2019
- Author(s)
  妻木範行
- Total Pages
  8
- Publisher
  公益社団法人日本整形外科学会
- Data Source
  KAKENHI-PROJECT-18H02923
[Book] THE BONE Vol.32 No.12018
- Author(s)
  妻木範行
- Total Pages
  5
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-18H02923
[Book] 医学書院2017
- Author(s)
  妻木範行
- Total Pages
  6
- Publisher
  標準整形外科学　第13版
- Data Source
  KAKENHI-PROJECT-15H02561
[Book] 分子リウマチ治療5　Vol.10 No.22017
- Author(s)
  妻木範行
- Total Pages
  4
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-15H02561
[Book] リウマチクリニックVol.252017
- Author(s)
  妻木範行
- Total Pages
  1
- Publisher
  メディカルビュー社
- Data Source
  KAKENHI-PROJECT-15H02561
[Book] OSAKA AKADEMY OF IMPLANTOLOGY　Voｌ.312017
- Author(s)
  妻木範行
- Total Pages
  3
- Publisher
  大阪口腔インプラント研究会
- Data Source
  KAKENHI-PROJECT-15H02561
[Book] 臨床雑誌「整形外科」2017
- Author(s)
  妻木範行
- Total Pages
  1
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-15H02561
[Book] 「関節外科－基礎と臨床」第36巻・第12号2017
- Author(s)
  妻木範行
- Total Pages
  4
- Publisher
  メディカルビュー社
- Data Source
  KAKENHI-PROJECT-15H02561
[Book] KeynoteR・A　vlol.42016
- Author(s)
  妻木範行
- Total Pages
  4
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-15H02561
[Book] 実験医学,第34巻第4号2016
- Author(s)
  妻木範行
- Total Pages
  5
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-15H02561
[Book] 先進医療　NAVIGATOR　今日の再生医療2016
- Author(s)
  妻木範行
- Total Pages
  2
- Publisher
  日本医学出版
- Data Source
  KAKENHI-PROJECT-15H02561
[Book] 日整会広報室ニュース（第106号）2016
- Author(s)
  妻木範行
- Total Pages
  1
- Publisher
  公益社団法人日本整形外科学会
- Data Source
  KAKENHI-PROJECT-15H02561
[Book] 月刊細胞2016
- Author(s)
  妻木範行
- Total Pages
  6
- Publisher
  ニュー・サイエンス社
- Data Source
  KAKENHI-PROJECT-15H02561
[Book] 月刊　糖尿病 DIABETES Vol.8 No62016
- Author(s)
  山下晃弘,妻木範行
- Total Pages
  7
- Publisher
  医学出版
- Data Source
  KAKENHI-PROJECT-15H02561
[Book] BIO Clinica2015
- Author(s)
  小田直純、妻木範行
- Total Pages
  4
- Publisher
  北陸館
- Data Source
  KAKENHI-PROJECT-24390354
[Book] 腎と骨代謝第28巻第3号2015
- Author(s)
  妻木範行、山下晃弘、岡田稔
- Total Pages
  7
- Publisher
  日本メディカルセンター
- Data Source
  KAKENHI-PROJECT-15H02561
[Book] 日本医師会雑誌第144巻　特別号（1）2015
- Author(s)
  妻木範行、箭原康人
- Total Pages
  3
- Publisher
  日本医師会
- Data Source
  KAKENHI-PROJECT-15H02561
[Book] 整形・災害外科2015
- Author(s)
  妻木範行
- Total Pages
  5
- Publisher
  金原出版
- Data Source
  KAKENHI-PROJECT-24390354
[Book] O.li.v.e－骨代謝と生活習慣病の関連－第5巻第3号2015
- Author(s)
  妻木範行
- Total Pages
  8
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-15H02561
[Book] 整形・災害外科Vol.582015
- Author(s)
  妻木範行
- Total Pages
  5
- Publisher
  金原出版
- Data Source
  KAKENHI-PROJECT-15H02561
[Book] A Tissue Regeneration Approach to Bone and Cartilage Repair2014
- Author(s)
  Noriyuki Tsumaki
- Total Pages
  13
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-24390354
[Book] Locomotive Pain Frontier Vol 1, No 1 整形外科と細胞リプログラミング2012
- Author(s)
  妻木範行
- Total Pages
  2
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-24390354
[Book] NEWエッセンシャル整形外科、第1章 (1) 骨2012
- Author(s)
  妻木範行
- Total Pages
  18
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-24390354
[Book] 再生医療叢書6、骨格系。多能性幹細胞を使った軟骨再生。(日本再生医療学会)2012
- Author(s)
  岡田稔、妻木範行
- Total Pages
  12
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-24390354
[Book] iPS細胞を経ない皮膚細胞から軟骨細胞への誘導。リウマチ病セミナーXXIII2012
- Author(s)
  妻木範行
- Total Pages
  7
- Publisher
  永井書店
- Data Source
  KAKENHI-PROJECT-24390354
[Book] 臨床整形外科「視座」整形外科医、基礎研究、生き物 Vol.47, No. 52012
- Author(s)
  妻木範行
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-24390354
[Book] 特集1.骨代謝研究におけるエピゲノムの最先端:真皮線維芽培養細胞から軟骨細胞様細胞へのダイレクト・リプログラミング2012
- Author(s)
  妻木範行
- Total Pages
  8
- Publisher
  CLINICAL CALCIUM
- Data Source
  KAKENHI-PROJECT-24390354
[Book] 軟骨細胞の分化制御機構と軟骨再生2012
- Author(s)
  妻木範行
- Total Pages
  4
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-24390354
[Book] Bone biology : Development and regeneration mechanisms in physiological and pathological conditions. In. Strategies in Regenerative Medicine2009
- Author(s)
  Yoshikawa, H., Tsumaki, N., Myoui, A.
- Publisher
  Springer, New York
- Data Source
  KAKENHI-PROJECT-20390398
[Book] Bone biology(Development and regeneration mechanisms in physiological and pathological conditions. In. Strategies in Regenerative Medicine)New York2009
- Author(s)
  Yoshikawa, H., Tsumaki, N., Myoui, A.
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-20390398
[Book] 臨床分子内分泌学32005
- Author(s)
  岩井貴男, 妻木範行, 吉川秀樹
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-15390458
[Book] 臨床分子内分泌学32005
- Author(s)
  岩井貴男, 妻木範行, 吉川秀樹
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-17659467
[Journal Article] Engraftment of allogeneic iPS cell-derived cartilage organoid in a primate model of articular cartilage defect2023
- Author(s)
  Abe Kengo、Yamashita Akihiro、Morioka Miho、Horike Nanao、Takei Yoshiaki、Koyamatsu Saeko、Okita Keisuke、Matsuda Shuichi、Tsumaki Noriyuki
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 804-804
- DOI
  10.1038/s41467-023-36408-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02923, KAKENHI-PROJECT-20K09432, KAKENHI-PROJECT-23K21466, KAKENHI-PROJECT-23K18327, KAKENHI-PROJECT-23K27720
[Journal Article] Repair of osteochondral defects: efficacy of a tissue-engineered hybrid implant containing both human MSC and human iPSC-cartilaginous particles2023
- Author(s)
  Nakagawa Shinichi、Ando Wataru、Shimomura Kazunori、Hart David A.、Hanai Hiroto、Jacob George、Chijimatsu Ryota、Yarimitu Seido、Fujie Hiromichi、Okada Seiji、Tsumaki Noriyuki、Nakamura Norimasa
- Journal Title
  
  npj Regenerative Medicine
  
  Volume: 8 Issue: 1 Pages: 59-59
- DOI
  10.1038/s41536-023-00335-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08773, KAKENHI-PROJECT-23K07813, KAKENHI-PROJECT-23K08676, KAKENHI-PROJECT-23K27720
[Journal Article] Chondrocyte-like cells in nucleus pulposus and articular chondrocytes have similar transcriptomic profiles and are paracrine-regulated by hedgehog from notochordal cells and subchondral bone2023
- Author(s)
  Hagizawa Hiroki、Koyamatsu Saeko、Okada Seiji、Kaito Takashi、Tsumaki Noriyuki
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 11 Pages: 1151947-1151947
- DOI
  10.3389/fcell.2023.1151947
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27720
[Journal Article] Destruction and regeneration in bone and cartilage2023
- Author(s)
  Tsumaki Noriyuki
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 43 Issue: 1
- DOI
  10.1186/s41232-023-00313-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27720
[Journal Article] Regeneration of joint surface defects by transplantation of allogeneic cartilage: application of iPS cell-derived cartilage and immunogenicity2023
- Author(s)
  Abe Kengo、Tsumaki Noriyuki
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 43 Issue: 1
- DOI
  10.1186/s41232-023-00307-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27720
[Journal Article] Human iPS cell-derived cartilaginous tissue spatially and functionally replaces nucleus pulposus2022
- Author(s)
  Kamatani Takashi、Hagizawa Hiroki、Yarimitsu Seido、Morioka Miho、Koyamatsu Saeko、Sugimoto Michihiko、Kodama Joe、Yamane Junko、Ishiguro Hiroyuki、Shichino Shigeyuki、Abe Kuniya、Fujibuchi Wataru、Fujie Hiromichi、Kaito Takashi、Tsumaki Noriyuki
- Journal Title
  
  Biomaterials
  
  Volume: 284 Pages: 121491-121491
- DOI
  10.1016/j.biomaterials.2022.121491
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19312, KAKENHI-PROJECT-18H02424, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06392, KAKENHI-PROJECT-18H02923, KAKENHI-PROJECT-21K19242, KAKENHI-PROJECT-20K06453
[Journal Article] Implantation of human iPS cell-derived cartilage in bone defects of mice2021
- Author(s)
  Iimori Yuki、Morioka Miho、Koyamatsu Saeko、Tsumaki Noriyuki
- Journal Title
  
  Tissue Engineering Part A
  
  Volume: - Issue: 21-22 Pages: 1355-1367
- DOI
  10.1089/ten.tea.2020.0346
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02923
[Journal Article] Generation of monkey iPS cell-derived cartilage lacking MHC class I molecules on the cell surface2021
- Author(s)
  Yuki Okutani, Kengo Abe, Akihiro Yamashita, Miho Morioka, Shuichi Matsuda, and Noriyuki Tsumaki
- Journal Title
  
  Tissue Engineering Part A
  
  Volume: 28 Pages: 94-106
- NAID
  120007184441
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02923
[Journal Article] Human pluripotent stem cell-derived cartilaginous organoids promote scaffold-free healing of critical size long bone defects2021
- Author(s)
  Tam Wai Long、Freitas Mendes Luis、Chen Xike、Lesage Raphaelle、Van Hoven Inge、Leysen Elke、Kerckhofs Greet、Bosmans Kathleen、Chai Yoke Chin、Yamashita Akihiro、Tsumaki Noriyuki、Geris Liesbet、Roberts Scott J.、Luyten Frank P.
- Journal Title
  
  Stem Cell Research & Therapy
  
  Volume: 12 Issue: 1 Pages: 513-528
- DOI
  10.1186/s13287-021-02580-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02924, KAKENHI-PROJECT-18H02923, KAKENHI-PROJECT-23K21466
[Journal Article] Recent progress of animal transplantation studies for treating articular cartilage damage using pluripotent stem cells2021
- Author(s)
  A. Yamashita, N. Tsumaki
- Journal Title
  
  Dev. Growth Differ.
  
  Volume: 63 Pages: 72-81
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02923
[Journal Article] iPS細胞を使用した創薬研究：軟骨疾患への応用2020
- Author(s)
  妻木範行
- Journal Title
  
  遺伝子医学
  
  Volume: 10 Pages: 87-93
- Data Source
  KAKENHI-PROJECT-18H02923
[Journal Article] Culture substrate‐associated YAP inactivation underlies chondrogenic differentiation of human induced pluripotent stem cells2020
- Author(s)
  Yamashita Akihiro、Yoshitomi Hiroyuki、Kihara Shunsuke、Toguchida Junya、Tsumaki Noriyuki
- Journal Title
  
  STEM CELLS Translational Medicine
  
  Volume: 10 Issue: 1 Pages: 115-127
- DOI
  10.1002/sctm.20-0058
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02923, KAKENHI-PROJECT-18H02929, KAKENHI-PROJECT-18H02924
[Journal Article] 同種iPS細胞由来軟骨を用いた関節軟骨損傷に対する再生医療2020
- Author(s)
  妻木範行
- Journal Title
  
  週刊医学のあゆみ
  
  Volume: 273巻 Pages: 1177-1181
- Data Source
  KAKENHI-PROJECT-18H02923
[Journal Article] Quality assessment tests for tumorigenicity of human iPS cell-derived cartilage2020
- Author(s)
  Takei Yoshiaki、Morioka Miho、Yamashita Akihiro、Kobayashi Tomohito、Shima Nobuyuki、Tsumaki Noriyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 12794-12805
- DOI
  10.1038/s41598-020-69641-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02923, KAKENHI-PROJECT-18H02924
[Journal Article] Evaluation of FGFR inhibitor ASP5878 as a drug candidate for achondroplasia2020
- Author(s)
  Ozaki Tomonori、Kawamoto Tatsuya、Iimori Yuki、Takeshita Nobuaki、Yamagishi Yukiko、Nakamura Hiroaki、Kamohara Masazumi、Fujita Kaori、Tanahashi Masayuki、Tsumaki Noriyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 20915-20926
- DOI
  10.1038/s41598-020-77345-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K12760, KAKENHI-PROJECT-18H02923
[Journal Article] 軟骨無形成症ーiPS細胞を活用して2020
- Author(s)
  妻木範行
- Journal Title
  
  臨床雑誌　整形外科
  
  Volume: 71 Pages: 1401-1406
- Data Source
  KAKENHI-PROJECT-18H02923
[Journal Article] Changes in acetyl-CoA mediate Sik3-induced maturation of chondrocytes in endochondral bone formation2019
- Author(s)
  Azuma Kosai, Nanao Horike, Yoshiaki Takei, Akihiro Yamashita, Kaori Fujita, Takashi Kamatani, Noriyuki Tsumaki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 516 Issue: 4 Pages: 1097-1102
- DOI
  10.1016/j.bbrc.2019.06.139
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02923, KAKENHI-PROJECT-18J40240
[Journal Article] A-674563 increases chondrocyte marker expression in cultured chondrocytes by inhibiting Sox9 degradation2018
- Author(s)
  Kobayashi T, Fujita K, Kamatani T, Matsuda S, Tsumaki N.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 495 Issue: 1 Pages: 1-1468
- DOI
  10.1016/j.bbrc.2017.11.180
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02561
[Journal Article] Proposal of patient-specific growth plate cartilage xenograft model for FGFR3 chondrodysplasia2018
- Author(s)
  Kimura T, Ozaki T, Fujita K, Yamashita A, Morioka M, Ozono K, Tsumaki NTsumaki
- Journal Title
  
  Osteoarthritis and Cartilage
  
  Volume: 26 Issue: 11 Pages: 1551-1561
- DOI
  10.1016/j.joca.2018.07.015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02923
[Journal Article] Considerations in hiPSC-derived cartilage for articular cartilage repair.2018
- Author(s)
  Yamashita A, Tamamura Y, Morioka M, Karagiannis P, Shima N, Tsumaki N
- Journal Title
  
  Inflamm Regen.
  
  Volume: 38 Issue: 1 Pages: 1-7
- DOI
  10.1186/s41232-018-0075-8
- NAID
  120006937645
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11636, KAKENHI-PROJECT-18H02923, KAKENHI-PROJECT-18H02924
[Journal Article] Integration Capacity of Human Induced Pluripotent Stem Cell-Derived Cartilage.2018
- Author(s)
  Chen X, Yamashita A, Morioka M, Senba T, Kamatani T, Watanabe A, Kosai A, Tsumaki N.
- Journal Title
  
  Tissue Eng Part A,
  
  Volume: 25 Issue: 5-6 Pages: 437-445
- DOI
  10.1089/ten.tea.2018.0133
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KT0108, KAKENHI-PROJECT-18H02923, KAKENHI-PROJECT-18H02924, KAKENHI-PROJECT-18H02826
[Journal Article] Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3.2016
- Author(s)
  Yahara Y, Takemori H, Okada M, Kosai A, Yamashita A, Kobayashi T, Fujita K, Itoh Y, Nakamura M, Fuchino H, Kawahara N, Fukui N, Watanabe A, Kimura T, Tsumaki N.
- Journal Title
  
  Nat Commun
  
  Volume: 7 Issue: 1 Pages: 10959-10959
- DOI
  10.1038/ncomms10959
- NAID
  120005741112
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861716, KAKENHI-PROJECT-15H02561, KAKENHI-PROJECT-15K15546
[Journal Article] Limited immunogenicity of human iPS cell-derived cartilages2016
- Author(s)
  Takeshi Kimura, Akihiro Yamashita, Keiichi Ozono and Noriyuki Tsumaki
- Journal Title
  
  Tissue Engineering Part A
  
  Volume: 22 Issue: 23-24 Pages: 1367-1375
- DOI
  10.1089/ten.tea.2016.0189
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02561
[Journal Article] iPS cell technologies and cartilage regeneration2015
- Author(s)
  Tsumaki N, Okada M, Yamashita A
- Journal Title
  
  Bone
  
  Volume: 70 Pages: 48-54
- DOI
  10.1016/j.bone.2014.07.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390354, KAKENHI-PROJECT-26861716
[Journal Article] Generation of Scaffoldless Hyaline Cartilaginous Tissue from Human iPSCs2015
- Author(s)
  Yamashita, A., Morioka, M., Yahara, Y., Okada, M., Kobayashi, T., Kuriyama, S., Matsuda, S., and Tsumaki, N
- Journal Title
  
  Stem cell reports
  
  Volume: 4 Issue: 3 Pages: 404-418
- DOI
  10.1016/j.stemcr.2015.01.016
- NAID
  120005767006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390354, KAKENHI-PROJECT-26861716
[Journal Article] Modeling type II collagenopathy skeletal dysplasia by directed conversion and induced pluripotent stem cells2015
- Author(s)
  Okada M, Ikegawa S, Morioka M, Yamashita A, Saito A, Sawai H,Murotsuki J, Ohashi H, Okamoto T, Nishimura G, Imaizumi K, Tsumaki N
- Journal Title
  
  Hum Mol Genet
  
  Volume: 24 Issue: 2 Pages: 299-313
- DOI
  10.1093/hmg/ddu444
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390354, KAKENHI-PROJECT-25251014, KAKENHI-PROJECT-26861716
[Journal Article] Cartilage intermediate layer protein promotes lumbar disc degeneration．2014
- Author(s)
  Seki S, Tsumaki N, Motomura H, Nogami M, Kawaguchi Y, Hori, T Suzuki K, Yahara Y, Higashimoto M, Oya T, Ikegawa S, Kimura T.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 446 Issue: 4 Pages: 876-881
- DOI
  10.1016/j.bbrc.2014.03.025
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390350, KAKENHI-PROJECT-24390354, KAKENHI-PROJECT-25462289
[Journal Article] iPS細胞で整形外科治療はどう変わるか2014
- Author(s)
  妻木範行
- Journal Title
  
  臨床整形外科
  
  Volume: 49 Pages: 63-71
- NAID
  40019924249
- Data Source
  KAKENHI-PROJECT-24390354
[Journal Article] Statin treatment rescues FGFR3 skeletal dysplasia phenotypes2014
- Author(s)
  Yamashita A, Morioka M, Kishi H, Kimura T, Yahara Y, Okada M, Fujita,K, Sawai H, Ikegawa S, Tsumaki N.
- Journal Title
  
  Nature
  
  Volume: 513(7519) Issue: 7519 Pages: 507-11
- DOI
  10.1038/nature13775
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390354, KAKENHI-PROJECT-26861716
[Journal Article] Cyp26b1 within the growth plate regulates bone growth in juvenile mice2014
- Author(s)
  Minegishi Y, Sakai Y, Yahara Y, Akiyama H, Yoshikawa H, Hosokawa K,Tsumaki N.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 454 Issue: 1 Pages: 12-18
- DOI
  10.1016/j.bbrc.2014.10.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390354, KAKENHI-PROJECT-26293336, KAKENHI-PROJECT-26861496
[Journal Article] Cell reprogramming for skeletal dysplasia drug repositioning2014
- Author(s)
  Karagiannis P, Tsumaki N
- Journal Title
  
  Cell Cycle
  
  Volume: 13(24) Issue: 24 Pages: 3791-3792
- DOI
  10.4161/15384101.2014.989944
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390354
[Journal Article] Sox9 reprogrammed dermal fibroblasts undergo hypertrophic differentiation in vitro and trigger endochondral ossification in vivo2014
- Author(s)
  Tam WL, Dorien FO, Hiramatsu K, Tsumaki N, Luyten FP, Roberts SJ
- Journal Title
  
  Cell Reprogram
  
  Volume: 16 Issue: 1 Pages: 29-39
- DOI
  10.1089/cell.2013.0060
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390354
[Journal Article] リプログラム軟骨細胞を用いた軟骨再生への展望2013
- Author(s)
  妻木範行
- Journal Title
  
  整形・災害外科
  
  Volume: 56 Pages: 573-584
- Data Source
  KAKENHI-PROJECT-24390354
[Journal Article] Direct induction of chondrogenic cells from human dermal fibroblast culture by defined factors2013
- Author(s)
  Outani H, Okada M, Yamashita A, Nakagawa K, Yoshikawa H, Tsumaki N.
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 10 Pages: e77365-e77365
- DOI
  10.1371/journal.pone.0077365
- NAID
  120005333915
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390354, KAKENHI-PROJECT-24890101
[Journal Article] Time-lapse observation of the dedifferentiation process in mouse chondrocytes using chondrocyte-specific reporters2013
- Author(s)
  Minegishi Y, Hosokawa K, Tsumaki N.
- Journal Title
  
  Osteoarthritis Cartilage
  
  Volume: 21 Issue: 12 Pages: 1968-1975
- DOI
  10.1016/j.joca.2013.09.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390354
[Journal Article] Osterix regulates calcification and degradation of chondrogenic matrices through matrix metalloproteinase 13 (MMP13) expression in association with transcription factor Runx2 during endochondral ossification2012
- Author(s)
  Nishimura, R., Wakabayashi, M., Hata, K., Matsubara, T., Honma, S., Wakisaka, S. .Kiyonari, H., Shioi, G., Yamaguchi, A., Tsumaki, N., Akiyama, H. and Yoneda, T
- Journal Title
  
  J. Biol. Chem
  
  Volume: 287 Pages: 33179-33190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390354
[Journal Article] SIK3 is essential forchondrocyte hypertrophy during skeletaldevelopment in mice2012
- Author(s)
  Sasagawa,S.,Takemori,H.,Uebi,T.,Ikegami,D.,Hiramatsu,K.,Ikegawa,S.,Yoshikawa,H.and Tsumaki,N.
- Journal Title
  
  Development
  
  Volume: 139巻 Issue: 6 Pages: 1153-1163
- DOI
  10.1242/dev.072652
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390421, KAKENHI-PROJECT-23791048
[Journal Article] An overgrowth disorder associated with excessive production of cGMP due to a gain-of-function mutation of the natriuretic peptide receptor 2 gene.2012
- Author(s)
  Miura K, Namba N, Fujiwara M, Ohata Y, Ishida H, Kitaoka T, Kubota T, Hirai H, Higuchi C, Tsumaki N, Yoshikawa H, Sakai N, Michigami T, Ozono K.
- Journal Title
  
  PLoS One
  
  Volume: 7 Issue: 8 Pages: e42180-e42180
- DOI
  10.1371/journal.pone.0042180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591227, KAKENHI-PROJECT-24390264, KAKENHI-PROJECT-24390354
[Journal Article] ダイレクトリプログラミングによる軟骨組織の作製2011
- Author(s)
  妻木範行
- Journal Title
  
  医学の歩み次世代iPS医療
  
  Volume: 239 Pages: 1332-1337
- Data Source
  KAKENHI-PROJECT-21390421
[Journal Article] Expression of dominant negative TGF-beta receptors inhibits cartilage formation in conditional transgenic mice2011
- Author(s)
  Hiramatsu K, Iwai T, Yoshikawa H, Tsumaki N
- Journal Title
  
  J Bone Miner Metab
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390421
[Journal Article] Induction ofchondrogenic cells from dermalfibroblast culture by defined factorsdoes not involve a pluripotent state.2011
- Author(s)
  Outani,H.,Okada,M.,Hiramatsu,K.,Yoshikawa,H and Tsumaki,N.
- Journal Title
  
  Biochem.Biophys.Res.Commun.
  
  Volume: 411巻 Issue: 3 Pages: 607-12
- DOI
  10.1016/j.bbrc.2011.06.194
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390421
[Journal Article] 特集骨・カルシウムUPDATE II.骨代謝研究UPDATE:軟骨細胞の分化制御2011
- Author(s)
  妻木範行
- Journal Title
  
  CLINICAL CALCIUM
  
  Volume: 21 Pages: 1863-1870
- Data Source
  KAKENHI-PROJECT-21390421
[Journal Article] Identification of small molecular compounds and fabrication of its aqueous solution by laser-ablation, expanding primordial cartilage2011
- Author(s)
  Ikegami D, Iwai T, Ryo SI, Gu N, Sugiyama T, Oh I, Yoshikawa H, Tsumaki N
- Journal Title
  
  Osteoarthritis Cartilage
  
  Volume: 19 Pages: 233-241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390421
[Journal Article] Conditional deletionof Bmpr1ab in differentiatedosteoclasts increases osteoblastic boneformation,increasing volume ofremodeling bone in mice.2011
- Author(s)
  Okamoto,M.,Murai,J.,Imai,Y.,Ikegami,D.,Kamiya,N.,Kato,S.,Mishita,Y.,Yoshikawa,H.and Tsumaki,N
- Journal Title
  
  J.BoneMiner.Res.
  
  Volume: 26巻 Issue: 10 Pages: 2511-22
- DOI
  10.1002/jbmr.477
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390421, KAKENHI-PROJECT-23659712, KAKENHI-PROJECT-23689066
[Journal Article] Generation of hyaline cartilaginous tissue from mouse adult dermal fibroblast culture by defined factors2011
- Author(s)
  Hiramatsu K, Sasagawa S, Outani H, Nakagawa K, Yoshikawa H, Tsumaki N
- Journal Title
  
  J Clin Invest
  
  Volume: 121 Pages: 640-657
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390421
[Journal Article] Sox9 in differentiated chondrocytes sustains chondrocyte survival and hypertrophy in part through p110 alpha-Akt pathways2011
- Author(s)
  Ikegami D, Akiyama H, Suzuki A, Nakamura T, Nakano T, Yoshikawa H, Tsumaki N
- Journal Title
  
  Development
  
  Volume: 138 Pages: 1507-1519
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390421
[Journal Article] 特集軟骨代謝研究の最前線Topics:軟骨特異的遺伝子改変マウスを用いた軟骨分化の解析2011
- Author(s)
  妻木範行
- Journal Title
  
  CLINICAL CALCIUM
  
  Volume: 21 Pages: 839-844
- Data Source
  KAKENHI-PROJECT-21390421
[Journal Article] Essential mesenchymal role of smallGTPase Rac1 in interdigital programmedcell death during limb development.2009
- Author(s)
  Suzuki D, Yamada A, Amano T, YasuharaR, Kimura A, Sakahara M,Tsumaki N,Takeda S, Tamura M, Nakamura M, Wada N,Nohno T, Shiroishi T, Aiba A, KamijoR.
- Journal Title
  
  Dev. Biol.
  
  Volume: 335 Pages: 396-406
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390421
[Journal Article] Essential mesenchymal role of small GTPase Rac1 in interdigital programmed cell death during limb development.2009
- Author(s)
  Suzuki D, Yamada A, Amano T, Yasuhara R, Kimura A, Sakahara M, Tsumaki N, Takeda S, Tamura M, Nakamura M, Wada N, Nohno T, Shiroishi T, Aiba A, Kamijo R.
- Journal Title
  
  Dev.Biol. 335
  
  Pages: 396-406
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390421
[Journal Article] Smad7 Inhibits Chondrocyte Differentiation at Multiplesteps during Endochondral Bone Formation and Down-regula tes P38 MAPK Pathways.2008
- Author(s)
  Iwai, T., Murai, J., Yoshikawa, H., Tsumaki, N
- Journal Title
  
  J. Biol. Chem. 283
  
  Pages: 27154-27164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659378
[Journal Article] Smad7 Inhibits Chondrocyte Differentiation at Multiple Steps during Endochondral Bone Formation and Down-regulates p38 MAPK Pathways2008
- Author(s)
  Iwai, T., Murai, J., Yoshikawa, H., and Tsumaki, N.
- Journal Title
  
  J Biol Chem 283
  
  Pages: 27154-27164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390415
[Journal Article] Insulation of the Ubiquitous Rxrb Promoter from the Cartilage-specific Adjacent Gene2008
- Author(s)
  Murai, J., Ikegami, D., Okamoto, M., Yoshikawa, H., and Tsumaki, N.
- Journal Title
  
  Col11a2. J Biol Chem 283
  
  Pages: 27677-27687
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390415
[Journal Article] Characteristics of fracture and related factors in patients with rheumatoid arthritis2008
- Author(s)
  Nampei, A., Hashimoto, J., Koyanagi, J., Ono, T., Hashimoto, H., Tsumaki, N., Tomita, T., Sugamoto, K., Nishimoto, N., Ochi, T., and Yoshikawa, H.
- Journal Title
  
  Mod Rheumatol 18
  
  Pages: 170-176
- NAID
  10024150369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390415
[Journal Article] Smad7 Inhibits Chondrocyte Differentiation at Multiple Steps during Endochondral Bone Formation and Down-regulates p38 MAPK Pathways.2008
- Author(s)
  Iwai, T., Murai, J., Yoshikawa, H., Tsumaki, N.
- Journal Title
  
  J Biol Chem 283
  
  Pages: 27154-27164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390415
[Journal Article] Characteristics of fracture and related factors in patients with rheumatoid arthritis.2008
- Author(s)
  Nampei, A., Hashimoto, J., Koyanagi, J., Ono, T., Hashimoto, H., Tsumaki, N., Tomita, T., Sugamoto, K., Nishimoto, N., Ochi, T., Yoshikawa, H.
- Journal Title
  
  Mod Rheumatol 18
  
  Pages: 170-176
- NAID
  10024150369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390415
[Journal Article] Insulation of the Ubiquitous Rxrb Promoter from the Cartilage-specific Adjacent Gene.2008
- Author(s)
  Murai, J., Ikegami, D., Okamoto, M., Yoshikawa, H., Tsumaki, N.
- Journal Title
  
  J. Biol. Chem. 283
  
  Pages: 27677-27687
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659378
[Journal Article] Insulation of the Ubiquitous Rxrb Promoter from the Cartilage-specific Adjacent Gene.2008
- Author(s)
  Murai, J., Ikegami, D., Okamoto, M., Yoshikawa, H., Tsumaki, N.
- Journal Title
  
  J. Biol. Chem. 283
  
  Pages: 27677-27687
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390415
[Journal Article] Characteristics of fracture and related factors in patients with rheumatoid arthritis.2008
- Author(s)
  Nampei, A., Hashimoto, J., Koyanagi, J., Ono, T., Hashimoto, H., Tsumaki, N., Tomita, T., Sugamoto, K., Nishimoto, N., 0chi, T., Yoshikawa, H.
- Journal Title
  
  Mod. Rheumatol. 18
  
  Pages: 170-176
- NAID
  10024150369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390415
[Journal Article] Insulation of the Ubiquitous Rxrb Promoter from the Cartilage-specific Adjacent Gene Col11a2.2008
- Author(s)
  Murai, J., Ikegami, D., Okamoto, M., Yoshikawa, H., Tsumaki, N.
- Journal Title
  
  J Biol Chem 283
  
  Pages: 27677-27687
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390415
[Journal Article] Smad7 Inhibits Chondrocyte Differentiation at Multiple Steps during Endochondral Bone Formation and Down-regula tes p38 MAPK Pathways.2008
- Author(s)
  Iwai, T., Murai, J., Yoshikawa, H., Tsumaki, N
- Journal Title
  
  J. Biol. Chem. 283
  
  Pages: 27154-27164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390415
[Journal Article] Characteristics of fracture and related factors in patients with rheumatoid arthritis.2008
- Author(s)
  Nampei, A., Hashimoto, J., Koyanagi, J., Ono, T., Hashimoto, H., Tsumaki, N., Tomita, T., Sugamoto, K., Nishimoto, N., 0chi, T., Yoshikawa, H.
- Journal Title
  
  Mod. Rheumatol. 18
  
  Pages: 170-176
- NAID
  10024150369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659378
[Journal Article] Hyaline cartilage formation and enchondral ossification modeled with KUM5 and OP9 chondroblasts2007
- Author(s)
  Sugiki, T., Uyama, T., Toyoda, M., Morioka, H., Kume, S., Miyado, K., Matsumoto, K., Saito, H., Tsumaki, N., Takahashi, Y., Toyama, Y., and Umezawa, A.
- Journal Title
  
  J Cell Biochem 100
  
  Pages: 1240-1254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390415
[Journal Article] Low-intensity pulsed ultrasound increases bone ingrowth into porous hydroxyapatite ceramic2007
- Author(s)
  Iwai T, Harada Y, Imura K, Iwabuchi S, Murai J, Hiramatsu K, Myoui A, Yoshikawa H, Tsumaki N
- Journal Title
  
  J Bone Miner Metab 25
  
  Pages: 392-399
- NAID
  10024125465
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390415
[Journal Article] Low-intensity pulsed ultrasound increases bone ingrowth into porous hydroxyapatite ceramic.2007
- Author(s)
  Iwai, T., Harada, Y., Imura, K., Iwabuchi, S., Murai, J., Hiramatsu, K., Myoui, A., Yoshikawa, H., Tsumaki, N.
- Journal Title
  
  J Bone Miner Metab 25
  
  Pages: 392-399
- NAID
  10024125465
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390415
[Journal Article] Low-intensity pulsed ultrasound increases bone ingrowth into porous hydroxyapatite ceramic2007
- Author(s)
  Iwai, T., Harada, Y., Imura, K., Iwabuchi, S., Murai, J., Hiramatsu, K., Myoui, A., Yoshikawa, H., and Tsumaki, N.
- Journal Title
  
  J Bone Miner Metab 25
  
  Pages: 392-399
- NAID
  10024125465
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390415
[Journal Article] Hyaline cartilage formation and enchondral ossification modeled with KUM5 and OP9 chondroblasts.2007
- Author(s)
  Sugiki, T., Uyama, T., Toyoda, M., Morioka, H., Kume, S., Miyado, K., Matsumoto, K., Saito, H., Tsumaki, N., Takahashi, Y., Toyama, Y., Umezawa, A.
- Journal Title
  
  J Cell Biochem 100
  
  Pages: 1240-1254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390415
[Journal Article] Low-intensity pulsed ultrasound increases bone ingrowth into porous hydroxyapatite ceramic2007
- Author(s)
  Iwai T, harada Y, Imura K, Iwabuchi S, Murai J, Hiramatsu K, Myoui A, Yoshikawa H, Tsumaki N
- Journal Title
  
  J Bone Miner Metab 25
  
  Pages: 392-399
- NAID
  10024125465
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659378
[Journal Article] 遺伝子改変マウスを用いたBMPシグナルによる骨軟骨形成機構の解析2006
- Author(s)
  妻木範行, 吉川秀樹
- Journal Title
  
  Arthritis 4
  
  Pages: 4-9
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209050
[Journal Article] Oxygen tension regulates chondrocyte differentiation and function during endochondral ossification.2006
- Author(s)
  Hirao, M., Tamai, N., Tsumaki, N., Yoshikawa, H., Myoui, A.
- Journal Title
  
  J Biol Chem 281
  
  Pages: 31079-31092
- Data Source
  KAKENHI-PROJECT-15209050
[Journal Article] Bone morphogenetic proteins in bone stimulate osteoclasts and osteoblasts during bone development.2006
- Author(s)
  Okamoto, M., Murai, J., Yoshikawa, H., Tsumaki, N.
- Journal Title
  
  J Bone Miner Res 21(7)
  
  Pages: 1022-1033
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390458
[Journal Article] Oxygen tension regulates chondrocyte differentiation and function during endochondral ossification.2006
- Author(s)
  Hirao, M., Tamai, N., Tsumaki, N., Yoshikawa, H., Myoui, A.
- Journal Title
  
  J Biol Chem 281(41)
  
  Pages: 31079-31092
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390415
[Journal Article] Bone morphogenetic proteins in bone stimulate osteoclasts and osteoblasts during bone development2006
- Author(s)
  Okamoto, M., Murai, J., Yoshikawa, H., Tsumaki, N
- Journal Title
  
  J Bone Miner Res 21, 7
  
  Pages: 1022-1033
- Data Source
  KAKENHI-PROJECT-18390415
[Journal Article] BMPシグナルと骨形成・骨吸収2006
- Author(s)
  妻木範行, 村井純子, 岩井貴男, 岡本美奈, 吉川秀樹
- Journal Title
  
  The Bone 20
  
  Pages: 343-348
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209050
[Journal Article] Bone morphogenetic proteins in bone stimulate osteoclasts and osteoblasts during bone development2006
- Author(s)
  Okamoto M., Murai, J., Yoshikawa, H., Tsumaki, N
- Journal Title
  
  J Bone Miner Res 21・7
  
  Pages: 1022-1033
- Data Source
  KAKENHI-PROJECT-17659467
[Journal Article] Oxygen tension regulates chondrocyte differentiation and function during endochondral ossification.2006
- Author(s)
  Hirao M., Tamai, N., Tsumaki N., Yoshikawa, H., Myoui, A
- Journal Title
  
  J Biol Chem, 281(41) : 31079-92, 2006. 281, 41
  
  Pages: 31079-31092
- Data Source
  KAKENHI-PROJECT-18390415
[Journal Article] Oxygen tension regulates chondrocyte differentiation and function during endochondral ossification.2006
- Author(s)
  Hirao, M., Tamai, N., Tsumaki, N., Yoshikawa, H., Myoui, A.
- Journal Title
  
  Journal of Biological Chemistry 281
  
  Pages: 31079-33192
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209050
[Journal Article] Bone morphogenetic proteins in bone stimulate osteoclasts and osteoblasts during bone development.2006
- Author(s)
  Okamoto, M., Murai, J., Yoshikawa, H., Tsumaki, N.
- Journal Title
  
  J Bone Miner Res 21
  
  Pages: 1022-1033
- Data Source
  KAKENHI-PROJECT-15209050
[Journal Article] 遺伝子改変マウスを用いたBMPシグナルによる骨・軟骨形成機構の解析.2006
- Author(s)
  妻木範行, 吉川秀樹
- Journal Title
  
  Arthritis 4, 1
  
  Pages: 4-9
- Data Source
  KAKENHI-PROJECT-17659467
[Journal Article] 骨格発生におけるBMPと関連分子群の生物活性2006
- Author(s)
  妻木範行, 吉川秀樹
- Journal Title
  
  CLINICAL CALCIUM 16
  
  Pages: 67-72
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209050
[Journal Article] 軟骨・骨形成における骨形成因子 (BMP) シグナルの役割.2006
- Author(s)
  妻木範行
- Journal Title
  
  Clinical Calcium 16, 4
  
  Pages: 138-142
- Data Source
  KAKENHI-PROJECT-17659467
[Journal Article] Oxygen tension regulates chondrocyte differentiation and function during endochondral ossification.2006
- Author(s)
  Hirao M., Tamai, N., Tsumaki N., Yoshikawa, H., Myoui, A
- Journal Title
  
  J Biol Chem, 281(41) : 31079-92, 2006 281, 41
  
  Pages: 31079-31092
- Data Source
  KAKENHI-PROJECT-17659467
[Journal Article] 最新原著レビュー低出カ超音波パルス照射は片側仮骨延長法を用いた高位脛骨骨切り術における延長仮骨治癒を促進する.2006
- Author(s)
  妻木範行
- Journal Title
  
  整形外科 57
  
  Pages: 1531-1535
- Data Source
  KAKENHI-PROJECT-18390415
[Journal Article] Bone morphogenetic proteins in bone stimulate osteoclasts and osteoblasts during bone development.2006
- Author(s)
  Okamoto, M., Murai, J., Yoshikawa, H., Tsumaki, N.
- Journal Title
  
  J Bone Miner Res 21(7)
  
  Pages: 1022-1033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390415
[Journal Article] 遺伝子改変マウスを用いたBMPシグナルによる骨・軟骨形成機構の解析.2006
- Author(s)
  妻木範行, 吉川秀樹
- Journal Title
  
  Arthritis 4, 1
  
  Pages: 4-9
- Data Source
  KAKENHI-PROJECT-18390415
[Journal Article] Bone morphogenetic proteins in bone stimulate osteoclasts and osteoblasts during bone development.2006
- Author(s)
  Okamoto, M., Murai, J., Yoshikawa, H., Tsumaki, N.
- Journal Title
  
  Journal of Bone Mineral Research 21
  
  Pages: 1022-1033
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209050
[Journal Article] Oxygen tension regulates chondrocyte differentiation and function during endochondral ossification2006
- Author(s)
  Hirao, M., Tamai, N., Tsumaki, N., Yoshikawa, H., and Myoui, A.
- Journal Title
  
  J Biol Chem 281(41)
  
  Pages: 31079-31092
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390415
[Journal Article] 軟骨・骨形成における骨形成因子(BMP)シグナルの役割.2006
- Author(s)
  妻木範行
- Journal Title
  
  Clinical Calcium 16, 4
  
  Pages: 138-142
- Data Source
  KAKENHI-PROJECT-18390415
[Journal Article] Bone morphogenetic proteins in bone stimulate osteoclasts and osteoblasts during bone development2006
- Author(s)
  Okamoto, M., Murai, J., Yoshikawa, H., and Tsumaki, N.
- Journal Title
  
  J Bone Miner Res 21(7)
  
  Pages: 1022-1033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390415
[Journal Article] 最新原著レビュー低出力超音波パルス照射は片側仮骨延長法を用いた高位脛骨骨切り術における延長仮骨治愈を促進する.2006
- Author(s)
  妻木範行
- Journal Title
  
  整形外科 57
  
  Pages: 1531-1535
- Data Source
  KAKENHI-PROJECT-17659467
[Journal Article] The role of bone morphogenetic proteins in endochondral bone formation.2005
- Author(s)
  Tsumaki, N., Yoshikawa, H.
- Journal Title
  
  Cytokine Growth Factor Reviews 16
  
  Pages: 279-285
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209050
[Journal Article] The role of bone morphogenetic proteins in endochondral bone formation.2005
- Author(s)
  Tsumaki, N., Yoshikawa, H
- Journal Title
  
  Cytokine Growth Factor Rev., 16
  
  Pages: 279-285
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390458
[Journal Article] The role of bone morphogenetic proteins in endochondral bone formation.2005
- Author(s)
  Tsumaki, N., Yoshikawa, H
- Journal Title
  
  Cytokine Growth Factor Rev., 16
  
  Pages: 279-285
- Data Source
  KAKENHI-PROJECT-17659467
[Journal Article] The role of bone morphogenetic proteins in endochondral bone formation.2005
- Author(s)
  Tsumaki, N., Yoshikawa, H
- Journal Title
  
  Cytokine Growth Factor Rev. 16
  
  Pages: 279-285
- Data Source
  KAKENHI-PROJECT-15390458
[Journal Article] 骨・軟骨研究の展開わかりやすい疾患動物解析(1)2005
- Author(s)
  村井純子, 吉川秀樹, 妻木範行
- Journal Title
  
  分子リウマチ 2
  
  Pages: 231-236
- Data Source
  KAKENHI-PROJECT-17659467
[Journal Article] The role of bone morphogenetic proteins in endochondral bone formation.2005
- Author(s)
  Tsumaki, N., Yoshikawa, H.
- Journal Title
  
  Cytokine Growth Factor Rev 16
  
  Pages: 279-285
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390458
[Journal Article] 骨・軟骨研究の展開分かりやすい疾患動物解析(1)2005
- Author(s)
  村井純子, 吉川秀樹, 妻木範行
- Journal Title
  
  分子リウマチ 2
  
  Pages: 231-236
- Data Source
  KAKENHI-PROJECT-15390458
[Journal Article] 骨・軟骨研究の展開分かりやすい疾患動物解析(2)2005
- Author(s)
  村井純子, 堀木充, 吉川秀樹, 妻木範行
- Journal Title
  
  分子リウマチ 2
  
  Pages: 304-309
- Data Source
  KAKENHI-PROJECT-15390458
[Journal Article] The role of bone morphogenetic proteins in endochondral bone formation2005
- Author(s)
  Tsumaki, N., Yoshikawa, H.
- Journal Title
  
  Cytokine Growth Factor Reviews 16
  
  Pages: 279-285
- Data Source
  KAKENHI-PROJECT-15209050
[Journal Article] 骨・軟骨研究の展開わかりやすい疾患動物解析(2)2005
- Author(s)
  村井純子, 堀木充, 吉川秀樹, 妻木範行
- Journal Title
  
  分子リウマチ 2
  
  Pages: 304-309
- Data Source
  KAKENHI-PROJECT-17659467
[Journal Article] Smad6/Smurfl overexpression in cartilage delays chondrocyte hypertrophy and causes dwarfism with osteopenia.2004
- Author(s)
  Horiki, M., Imamura, T., Okamoto, M., Hayashi, M., Murai, J., Myoui, A., Ochi, T., Miyazono, K., Yoshikawa, H., Tsumaki, N.
- Journal Title
  
  J Cell Biol 165(3)
  
  Pages: 433-445
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390458
[Journal Article] Low-intensity pulsed ultrasound accelerates maturation of callus in patients treated with opening-wedge high tibial osteotomy by hemicallotasis.2004
- Author(s)
  Tsumaki, N., Kakiuchi, M., Sasaki, J., Ochi, T., Yoshikawa, H.
- Journal Title
  
  J Bone Joint Surg Am 86-A(11)
  
  Pages: 2399-2405
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390458
[Journal Article] Smad6/Smurfl overexpression in cartilage delays chondrocyte hypertrophy and causes dwarfism with osteopenia.2004
- Author(s)
  Horiki, M., Imamura, T., Okamoto, M., Hayashi, M., Murai, J., Myoui, A., Ochi, T., Miyazono, K., Yoshikawa, H., Tsumaki, N.
- Journal Title
  
  Journal of Cell Biology 65
  
  Pages: 433-445
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209050
[Journal Article] Low-Intensity pulsed ultrasound accelerates maturation of callus in opening-wedge high tibial osteotomy by hemicallotasis.2004
- Author(s)
  Tsumaki, N. et al.
- Journal Title
  
  Journal of Bone and Joint Surgery(Am) 86
  
  Pages: 2399-2405
- Data Source
  KAKENHI-PROJECT-15390458
[Journal Article] Low-Intensity pulsed ultrasound accelerates maturation of callus in opening-wedge high tibial osteotomy by hemicallotasis.2004
- Author(s)
  Tsumaki, N. et al.
- Journal Title
  
  Journal of Bone and Joint Surgery (Am) 86
  
  Pages: 2399-2405
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390458
[Journal Article] Low-intensity pulsed ultrasound accelerates maturation of callus in patients treated with opening-wedge high tibial osteotomy by hemicallotasis.2004
- Author(s)
  Tsumaki, N., Kakiuchi, M., Sasaki, J., Ochi, T., Yoshikawa, H.
- Journal Title
  
  Journal of Bone and Joint Surgery 86A
  
  Pages: 2399-2405
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209050
[Journal Article] 内軟骨性骨化調節にみるBMP(骨形成因子)ならびにSmadの役割2004
- Author(s)
  妻木範行, 他
- Journal Title
  
  Clinical Calsium 14
  
  Pages: 1072-1077
- Data Source
  KAKENHI-PROJECT-15390458
[Journal Article] Smad6/Smurf1 overexpression in cartilage delays chondrocyte hypertrophy and causes dwarfism with osteopenia.2004
- Author(s)
  Horiki, M., Imamura, T., Okamoto, M., Hayashi, M., Murai, J., Myoui, A., Ochi, T., Miyazono, K., Yoshikawa, H., Tsumaki, N.
- Journal Title
  
  Journal of Cell Biology 65
  
  Pages: 433-445
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209050
[Journal Article] OAとコラーゲン代謝2004
- Author(s)
  妻木範行
- Journal Title
  
  医学のあゆみ 211
  
  Pages: 294-298
- Data Source
  KAKENHI-PROJECT-15390458
[Journal Article] Hyaline cartilage formation and enchondral ossification modeled with KUM5 and OP9 chondroblasts.
- Author(s)
  Sugiki, T., Uyama, T., Toyoda, M., Morioka, H., Kume, S., Miyado, K., Matsumoto, K., Saito, H., Tsumaki N., Takahashi, Y., Toyama, Y., Umezawa, A
- Journal Title
  
  J Cell Biochem (in press)
- Data Source
  KAKENHI-PROJECT-17659467
[Journal Article] Hyaline cartilage formation and enchondral ossification modeled with KUM5 and OP9 chondroblasts.
- Author(s)
  Sugiki, T., Uyama, T., Toyoda, M., Morioka, H., Kume, S., Miyado, K., Matsumoto, K., Saito, H., Tsumaki, N., Takahashi, Y., Toyama, Y., Umezawa, A
- Journal Title
  
  J Cell Biochem (in press)
- Data Source
  KAKENHI-PROJECT-18390415
[Patent] ルブリシン局在軟骨様組織、その製造方法及びそれを含む関節軟骨損傷治療用組成物2018
- Inventor(s)
  妻木範行
- Industrial Property Rights Holder
  妻木範行
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-18H02923
[Patent] FGFR3病の予防剤または治療剤2017
- Inventor(s)
  妻木範行
- Industrial Property Rights Holder
  妻木範行
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-15H02561
[Patent] 新規軟骨細胞誘導方法2016
- Inventor(s)
  妻木範行
- Industrial Property Rights Holder
  妻木範行
- Industrial Property Rights Type
  特許
- Filing Date
  2016-02-19
- Data Source
  KAKENHI-PROJECT-15H02561
[Patent] 軟骨疾患治療薬のスクリーニング方法および軟骨疾患治療用改変軟骨細胞2011
- Inventor(s)
  妻木範行、竹森洋
- Industrial Property Rights Holder
  大阪大学、医薬基盤研究所
- Industrial Property Number
  2011-121788
- Filing Date
  2011-05-31
- Data Source
  KAKENHI-PROJECT-21390421
[Patent] 軟骨疾患治療薬のスクリーニング方法および軟骨疾患治療用改変軟骨細胞2011
- Inventor(s)
  妻木範行
- Industrial Property Rights Holder
  大阪大学医薬基盤研究所
- Filing Date
  2011-05-31
- Data Source
  KAKENHI-PROJECT-21390421
[Patent] 軟骨細胞様細胞、及びその製造方法2009
- Inventor(s)
  妻木範行
- Industrial Property Rights Holder
  大阪大学, TLOひょうご
- Filing Date
  2009-12-18
- Overseas
- Data Source
  KAKENHI-PROJECT-21390421
[Presentation] 骨格発生と再生治療の研究開発2024
- Author(s)
  妻木　範行
- Organizer
  第 27 回リウマチフォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-23K27720
[Presentation] 運動器再生医療の現在と未来「関節軟骨欠損に対する同種iPS細胞由来軟骨移植による再生」2024
- Author(s)
  阿部　健吾、妻木　範行
- Organizer
  第36回日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-23K27720
[Presentation] 再生医療の基礎開発、臨床応用そして企業とのコラボレーション2024
- Author(s)
  妻木　範行
- Organizer
  第 5 回再生医療等製品および周辺産業の規制動向討論会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27720
[Presentation] 内軟骨性骨化におけるCrispld1の機能解明2024
- Author(s)
  山下　晃弘・妻木　範行
- Organizer
  第36回日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-23K27720
[Presentation] “Construction of biodigital twin for osteoarthritis”2024
- Author(s)
  妻木　範行
- Organizer
  International PRIMe Symposium
- Data Source
  KAKENHI-PROJECT-23K27720
[Presentation] 再生医療等製品の実用化を促進するためのチームビルディング2023
- Author(s)
  妻木範行
- Organizer
  第22回日本再生医療学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] ヒトiPS細胞由来軟骨様組織を用いた椎間板再生2023
- Author(s)
  海渡貴司・釜谷崇志・萩澤宏樹・妻木範行
- Organizer
  第35回日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 軟骨再生医療の最先端軟骨発生研究とiPS細胞を使った軟骨再生治療法開発2023
- Author(s)
  妻木　範行
- Organizer
  第1回日本膝関節学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27720
[Presentation] 新規軟骨関連遺伝子Crispld1の機能解明2023
- Author(s)
  山下　晃弘・妻木　範行
- Organizer
  第22回運動器科学研究会
- Data Source
  KAKENHI-PROJECT-23K27720
[Presentation] 同種iPS細胞由来軟骨移植による関節軟骨損傷の再生治療法の開発2023
- Author(s)
  妻木　範行
- Organizer
  第44回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-23K27720
[Presentation] 霊長類関節軟骨欠損モデルにおける同種iPS細胞由来軟骨の生着と機能2023
- Author(s)
  阿部　健吾、妻木　範行
- Organizer
  第41回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-23K27720
[Presentation] 臨床までのアプローチが異なる運動器再生医療の実際2023
- Author(s)
  妻木範行
- Organizer
  第22回日本再生医療学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 霊長類膝軟骨欠損モデルにおける同種 iPS 細胞由来軟骨移植による修復2023
- Author(s)
  阿部　健吾、山下　晃弘、松田　秀一、妻木　範行
- Organizer
  第96回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-23K27720
[Presentation] 根岸　孝寛・妻木　範行2023
- Author(s)
  妻木　範行
- Organizer
  第22回運動器科学研究会
- Data Source
  KAKENHI-PROJECT-23K27720
[Presentation] "軟骨　修復と再生　細胞リプログラミングと関節軟骨再生"2023
- Author(s)
  妻木範行
- Organizer
  第35回日本軟骨代謝学会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 同種iPS細胞由来軟骨移植による関節軟骨損傷の再生治療法の開発2023
- Author(s)
  妻木　範行
- Organizer
  第59回日本移植学会総会
- Data Source
  KAKENHI-PROJECT-23K27720
[Presentation] iPS Cells: A Game Changer Presentation Topic:Stem Cells2023
- Author(s)
  妻木　範行
- Organizer
  ICRS 2023 | 17th ICRS World Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27720
[Presentation] 再生，創薬による早期関節軟骨損傷・変性の治療方法の開発2023
- Author(s)
  妻木　範行
- Organizer
  第96回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-23K27720
[Presentation] ヒトiPS細胞由来軟骨を用いた限局した関節軟骨治療法の開発2023
- Author(s)
  山下　晃弘・妻木　範行
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-23K27720
[Presentation] 「軟骨発生研究と骨格疾患の再生治療」2023
- Author(s)
  妻木範行
- Organizer
  第43回メディコピア教育講演シンポジウム「再生医療の最前線」
- Invited
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] "Advances on osteoarthritis pathogenesis and treatmen　 Application of iPS cell-derived cartilage to regenerate articular cartilage damage"2022
- Author(s)
  妻木範行
- Organizer
  第66回日本リウマチ学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] iPS細胞を用いた関節軟骨再生治療法の開発2022
- Author(s)
  妻木範行
- Organizer
  第122回日本外科学会定期学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] Creation of iPS cell-derived cartilage and regenerative treatment for articular cartilage damage2022
- Author(s)
  妻木範行
- Organizer
  Monash University-Osaka University Joint Symposium 2022
- Invited
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 「軟骨発生の基礎研究から骨格疾患の再生治療法開発へ」2022
- Author(s)
  妻木範行
- Organizer
  第37回日本整形外科学会基礎学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 再生医療の最前線「同種iPS細胞由来軟骨移植による関節軟骨損傷の再生」2022
- Author(s)
  妻木範行
- Organizer
  第37回日本整形外科学会基礎学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 同種iPS細胞由来軟骨移植による関節軟骨損傷の再生2022
- Author(s)
  妻木　範行
- Organizer
  日本再生医療学会
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 軟骨発生の基礎研究から関節軟骨損傷の再生治療開発へ2022
- Author(s)
  妻木　範行
- Organizer
  日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 「霊長類膝軟骨欠損モデルにおける同種 iPS 細胞由来軟骨移植の有効性」2022
- Author(s)
  阿部健吾・山下晃弘・妻木範行
- Organizer
  第40回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] ラット尾椎移植モデルにおける移植後iPSC由来軟骨のシングルセルRNA解析2022
- Author(s)
  萩澤宏樹・釜谷崇志・小屋松冴子・阿部訓也・山根順子・藤淵航・海渡貴司・妻木範行
- Organizer
  第43回日本炎症・再生医学会The 43rd Annual Meeting of the Japanese Society of Inflammation and Regeneration,ポスター
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] Developmental biology of cartilage and cartilage regeneration2022
- Author(s)
  妻木範行
- Organizer
  第18回Bone Biology Forum
- Invited
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 骨格発生の基礎研究から関節軟骨と椎間板髄核の再生治療法開発へ2022
- Author(s)
  妻木範行
- Organizer
  第21回阪大整形外科開業医会講演会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 軟骨発生の基礎研究から骨格疾患の再生治療法開発へ2022
- Author(s)
  妻木範行
- Organizer
  産業医科大学大学院講義
- Invited
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] "軟骨発生研究から軟骨再生治療の実現へ：iPS細胞を用いて"，2022
- Author(s)
  妻木範行
- Organizer
  "香川県整形外科医会講演会（共催；香川県整形外科医会・日本臓器製薬株式会社）
- Invited
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] iPS細胞由来軟骨様髄核組織の移植による椎間板再生の検討2022
- Author(s)
  釜谷崇志・海渡貴司・吉川秀樹・妻木範行
- Organizer
  第40回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] "私の履歴書　基礎研究を志した理由やサイエンスの面白さについて"，2022
- Author(s)
  妻木範行
- Organizer
  令和私塾（大阪大学)
- Invited
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 同種iPS細胞由来軟骨を用いた関節軟骨損傷再生治療法の開発2022
- Author(s)
  妻木範行
- Organizer
  第95回日本整形外科学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] iPS細胞技術を用いた新規軟骨疾患治療法の開発2022
- Author(s)
  妻木範行
- Organizer
  研究交流会（FBS コロキウム），大阪大学医学系研究科生命機能研究科
- Invited
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 霊長類膝軟骨欠損モデルにおける同種iPS細胞由来軟骨移植による再生2022
- Author(s)
  阿部健吾・奥谷祐希・山下晃弘・松田秀一・妻木範行
- Organizer
  第43回日本炎症・再生医学会The 43rd Annual Meeting of the Japanese Society of Inflammation and Regeneration,ポスター
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 動物モデルを用いた膝関節軟骨損傷に対する同種 iPS 細胞由来軟骨移植2022
- Author(s)
  阿部健吾、奥谷祐希、山下晃弘、森岡美帆、松田秀一、妻木範行
- Organizer
  第１２回 Orthopaedic Research Club
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 同種iPS細胞由来軟骨移植による関節軟骨損傷の再生治療法の開発2022
- Author(s)
  妻木　範行
- Organizer
  第43回日本炎症・再生医学会The 43rd Annual Meeting of the Japanese Society of Inflammation and Regeneration,ポスター
- Invited
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] ヒトiPS細胞由来軟骨を用いた骨欠損治療2021
- Author(s)
  飯森由紀、妻木範行
- Organizer
  第11回Orthopedic Research Club
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] Application of iPS cell-derived cartilage to regenerate articular cartilage damage.2021
- Author(s)
  妻木　範行
- Organizer
  the 6th world congress of the Tissue Engineering and Regenerative Medicine International Society
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 同種iPS細胞由来軟骨移植による関節軟骨損傷の再生2021
- Author(s)
  妻木　範行
- Organizer
  第39回日本骨代謝学会
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 軟骨無形成症の疾患モデル開発と治療薬探索2021
- Author(s)
  妻木　範行
- Organizer
  第39回日本骨代謝学会
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 軟骨発生の基礎研究から軟骨再生治療の実現への挑戦2021
- Author(s)
  妻木　範行
- Organizer
  第10回大阪大学　健康・医療クロスイノベーションフォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 軟骨発生の基礎研究から関節軟骨損傷の再生治療開発へ2021
- Author(s)
  妻木　範行
- Organizer
  第36回なにわリウマチフォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] Application of iPS Cell-derived Cartilage to Regenerate Articular Cartilage Damage2021
- Author(s)
  妻木　範行
- Organizer
  The Chinese Society for Stem Cell and Research (CSSCR)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 軟骨発生の基礎研究から再生治療実現への挑戦2021
- Author(s)
  妻木　範行
- Organizer
  内分泌・代謝内科学Global Meeting
- Invited
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] Application of iPS cell-derived cartilage to regenerate articular cartilage damage2021
- Author(s)
  妻木　範行
- Organizer
  JOSKAS/JOSSM meeting 2021 第13回日本関節鏡・膝・スポーツ整形外科学会学術集会・第47回日本整形外科スポーツ医学会学術集会シンポジウム「軟骨再生医療の evolusion」
- Invited
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] iPS細胞を用いた関節軟骨損傷の再生2021
- Author(s)
  妻木　範行
- Organizer
  第36回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 塩誘導性キナーゼ3（SIK3）は関節軟骨表層へのせん断力負荷により不活性化されルブリシン発現を促進する2020
- Author(s)
  武井義明、妻木範行
- Organizer
  第38回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] iPS細胞由来軟骨を用いた関節軟骨損傷治療法の開発2020
- Author(s)
  妻木範行
- Organizer
  第93回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] Endochondral bone formation and cell reprogramming2020
- Author(s)
  Noriyuki Tsumaki
- Organizer
  The 8th Seoul Symposium on Bone Health(SSBH) & the 32nd Fall Scientific Congress of the Korean Society for Bone and Mineral Research(KSBMR).
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 軟骨破壊機序と治療戦略2020
- Author(s)
  妻木範行
- Organizer
  第64回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] iPS細胞由来軟骨を用いた骨欠損修復2020
- Author(s)
  飯森由紀、妻木範行
- Organizer
  第38回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 同種iPS細胞由来軟骨による関節軟骨損傷再生治療法の開発2020
- Author(s)
  妻木範行
- Organizer
  第39回日本運動器移植・再生医学研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 内軟骨性骨化におけるYes-associated protein(Yap)の役割の解析2020
- Author(s)
  尾崎友則、妻木範行
- Organizer
  第38回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 細胞リプログラミング技術と軟骨再生研究2020
- Author(s)
  妻木範行
- Organizer
  第135回中部日本整形外科災害外科学会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] iPS細胞など再生医療について2020
- Author(s)
  妻木範行
- Organizer
  金蘭千里高校出前授業
- Invited
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 軟骨の基礎研究と細胞リプログラミング技術2020
- Author(s)
  妻木範行
- Organizer
  第35回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] ヒトiPS細胞由来軟骨による限局した関節軟骨治療法の開発2020
- Author(s)
  山下晃弘、妻木範行
- Organizer
  第38回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 関節軟骨損傷／破壊に対する新しい治療方法の開発研究2020
- Author(s)
  妻木範行
- Organizer
  第11回北摂リウマチ倶楽部
- Invited
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 同種iPS細胞由来軟骨による関節軟骨損傷治療法の開発2020
- Author(s)
  妻木範行
- Organizer
  第41回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 関節軟骨変性に対する治療方法の開発：iPS細胞由来軟骨による再生とSIK3阻害剤による創薬2019
- Author(s)
  妻木範行
- Organizer
  第92回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] iPS細胞技術を用いた関節軟骨疾患の新しい治療方法開発2019
- Author(s)
  妻木範行
- Organizer
  大阪府臨床麻酔科医会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] ヒトiPS細胞由来軟骨移植後の関節軟骨様層構造形成の機序解明2019
- Author(s)
  武井義明、妻木範行
- Organizer
  第10回 Orthopedic Research Club
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] Application of iPS cell-derived cartilage to treatment of articular cartilage damage2019
- Author(s)
  Noriyuki Tsumaki
- Organizer
  Global Bio Conference2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 抗老化因子Δ１３３ｐ５３による軟骨細胞への分化誘導と増殖の分子機構解明とその応用2019
- Author(s)
  藤田香里、妻木範行
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 椎間板変性の治療方法の開発2019
- Author(s)
  釜谷崇志、妻木範行
- Organizer
  第4回Skeletal Science Retreat
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 軟骨リプログラミング技術と軟骨疾患治療方法の開発2019
- Author(s)
  妻木範行
- Organizer
  産業医科大学医学部　大学院講義
- Invited
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] ヒトiPS細胞由来軟骨を用いた骨欠損治療2019
- Author(s)
  飯森由紀、妻木範行
- Organizer
  第4回Skeletal Science Retreat
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 内軟骨性骨化におけるYes-associated protein (Yap)の役割の解明2019
- Author(s)
  尾崎友則、妻木範行
- Organizer
  第4回Skeletal Science Retreat
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] Application of iPS cell-derived cartilage to regenerate articular cartilage damage2019
- Author(s)
  Noriyuki Tsumaki
- Organizer
  2019 Zhangjiang International Summit on Cell Therapy
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] FGFR3軟骨形成異常症の疾患iPS細胞モデルと創薬研究2019
- Author(s)
  妻木範行
- Organizer
  30回日本小児整形外科学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] ヒトiPS細胞由来軟骨を用いた骨欠損治療2019
- Author(s)
  飯森由紀、妻木範行
- Organizer
  第10回 Orthopedic Research Club
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] iPS細胞を用いた再生医療と疾患モデル研究2018
- Author(s)
  妻木範行
- Organizer
  第39回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] iPS細胞由来軟骨による再生医療最前線2018
- Author(s)
  妻木範行
- Organizer
  第23回日本基礎理学療法学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] Application of iPS cells to regenerate articular cartilage damage and model skeletal dysplasia2018
- Author(s)
  Noriyuki Tsumaki
- Organizer
  The NYSCF Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] iPS細胞を使った骨系統疾患モデルと関節軟骨再生研究2018
- Author(s)
  妻木範行
- Organizer
  日本筋学会第4回学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] iPS細胞を使った関節軟骨再生と骨系統疾患モデル研究2018
- Author(s)
  妻木範行
- Organizer
  第32回日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] Repair of focal articular cartilage defect with human iPSC-derived cartilage in a mini-pig model treated with immunosuppressor2018
- Author(s)
  Akihiro Yamashita,Noriyuki Tsumaki
- Organizer
  5th TERMIS World Congress - 2018 Kyoto, Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 整形外科領域の再生医療の現状と展望2018
- Author(s)
  妻木範行
- Organizer
  第18回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] Integration capacity of human iPS cell-derived cartilage2018
- Author(s)
  陳　皙可、妻木範行
- Organizer
  第5回ベーシックリサーチカンファレンス
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 関節軟骨欠損に対するiPS細胞由来軟骨を用いた治療について2018
- Author(s)
  小林与人、妻木範行
- Organizer
  第33回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] Application of iPSC technology to disease modeling for chondrodysplasia2018
- Author(s)
  Noriyuki Tsumaki
- Organizer
  5th TERMIS World Congress - 2018 Kyoto, Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 細胞膜表面MHC class I発現を欠失したサルiPS細胞由来軟骨の作製の試み2018
- Author(s)
  奥谷祐希、妻木範行
- Organizer
  第32回日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-18H02923
[Presentation] 同種iPS細胞由来軟骨による軟骨再生治療法の開発2017
- Author(s)
  妻木範行
- Organizer
  第4回ベーシックリサーチカンファレンス
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] iPS細胞を使った関節軟骨の再生研究2017
- Author(s)
  妻木範行
- Organizer
  一般社団法人日本再生医療学会
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] iPS細胞を用いた骨系統疾患研究2017
- Author(s)
  妻木範行
- Organizer
  第24回母子医療センターシンポジウム
- Place of Presentation
  大阪市
- Year and Date
  2017-02-17
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] 同種iPS 細胞由来軟骨による関節軟骨損傷の再生治療研究2017
- Author(s)
  妻木範行
- Organizer
  第35回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] Application of iPS cell technologies to regenerate articular cartilage damage and model skeletal dysplasia2017
- Author(s)
  Noriyuki Tsumaki
- Organizer
  CiRA 2017 International Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] 変形性関節症に対する新たな治療標的2017
- Author(s)
  山下晃弘、妻木範行
- Organizer
  第45回日本関節病学会
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] Application of iPS cell technologies to research for cartilage diseases2017
- Author(s)
  Noriyuki Tsumaki
- Organizer
  JSPS-NIH Forum
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] 軟骨細胞分化制御と関節軟骨病変の再生治療2017
- Author(s)
  妻木範行
- Organizer
  東京都臨床整形外科医会（TCOA）平成28年度秋季研修会
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] 軟骨細胞の分化制御と軟骨疾患の新しい治療方法の開発2017
- Author(s)
  妻木範行
- Organizer
  第52回骨Ca代謝研究会
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] iPS細胞技術を使った関節軟骨再生治療法の開発2017
- Author(s)
  妻木範行
- Organizer
  平成 29年度学術功労者表彰式第546回「医学研修の日」
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] 同種iPS細胞を用いた関節軟骨損傷に対する再生治療法の開発2017
- Author(s)
  妻木範行
- Organizer
  第9回日本関節鏡・膝・スポーツ整形外科学会（JOSKAS 2017）
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] 同種iPS細胞由来軟骨による関節軟骨再生治療法の開発2017
- Author(s)
  妻木範行
- Organizer
  第17回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] 軟骨の分化制御と再生治療研究2017
- Author(s)
  妻木範行
- Organizer
  第２回　United Front against Rheumatism
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] iPS細胞を使った軟骨疾患研究2017
- Author(s)
  妻木範行
- Organizer
  第150回ポバール会
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] 軟骨細胞分化研究と関節軟骨損傷の治療方法開発2017
- Author(s)
  妻木範行
- Organizer
  第35回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] 細胞リプログラミング技術と軟骨疾患の創薬研究2017
- Author(s)
  妻木範行
- Organizer
  先導的学際機構創薬サイエンス部門シンポジウム
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] iPS細胞技術を使った軟骨再生治療方法の開発2017
- Author(s)
  妻木範行
- Organizer
  平成29年度　神戸再生医療勉強会（第6回）特別講演
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] iPS cell-derived cartilage can repair articular cartilage damage through mechanism of substitution2017
- Author(s)
  Tomohito Kobayashi,Noriyuki Tsumaki
- Organizer
  2018 Bones and Teeth Gordon Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] 同種iPS細胞由来軟骨による関節軟骨損傷の再生治療研究2017
- Author(s)
  妻木範行
- Organizer
  第38回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] Application of iPS cell technologies to the reserch of cartilage deseases2017
- Author(s)
  Noriyuki Tsumaki
- Organizer
  2018 Bones and Teeth Gordon Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] ラットの膝関節軟骨欠損モデルを用いた、ヒトiPS細胞由来軟骨移植の安全性評価2017
- Author(s)
  小林与人、妻木範行
- Organizer
  第38回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] ラット骨端線へのiPS細胞由来軟骨particle移植2016
- Author(s)
  小林与人、妻木範行
- Organizer
  第7回Orthopedic Research Club
- Place of Presentation
  千葉県木更津市
- Year and Date
  2016-11-19
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] iPS細胞を使った軟骨疾患の新しい研究2016
- Author(s)
  妻木範行
- Organizer
  第15回　新潟骨・関節フォーラム
- Place of Presentation
  新潟県
- Year and Date
  2016-06-22
- Invited
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] The 5th International Research Conference on Multiple Hereditary Exostoses (MHE Research Foundation)2016
- Author(s)
  Noriyuki Tsumaki
- Organizer
  Application of iPSC technology to disease modeling for chondrodysplasia
- Place of Presentation
  USA
- Year and Date
  2016-05-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] iPS細胞を用いた新しい軟骨疾患治療方法の開発2016
- Author(s)
  妻木範行
- Organizer
  奈良県整形外科研究会
- Place of Presentation
  奈良県
- Year and Date
  2016-10-29
- Invited
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] 骨系統疾患の疾患iPS細胞モデルと創薬2016
- Author(s)
  妻木範行
- Organizer
  理研シンポジウム第3回創薬ワークショップ
- Place of Presentation
  横浜
- Year and Date
  2016-03-03
- Invited
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] Application of iPS cell technologies to cartilage regeneration and disease modeling2016
- Author(s)
  Noriyuki Tsumaki
- Organizer
  Swiss-Kyoto Joint Symposium
- Place of Presentation
  Kyoto
- Year and Date
  2016-06-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] 第39回日本分子生物学会年会2016
- Author(s)
  妻木範行
- Organizer
  骨系統疾患の疾患iPS細胞モデルと創薬研究
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] iPS細胞モデルによる骨系統疾患の病態解明と創薬2016
- Author(s)
  妻木範行
- Organizer
  第15回日本再生医療学会総会
- Place of Presentation
  大阪
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] Use of cell reprogramming technologies in research on cartilage diseases2016
- Author(s)
  Noriyuki Tsumaki
- Organizer
  The Croucher Foundation Advanced Study Institute (ASI)
- Place of Presentation
  Hong Kong
- Year and Date
  2016-01-11
- Invited
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] ヒトiPS細胞由来軟骨細胞を用いた半月板損傷修復の試み2016
- Author(s)
  奥谷祐希、妻木範行
- Organizer
  第7回Orthopedic Research Club
- Place of Presentation
  千葉県木更津市
- Year and Date
  2016-11-19
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] Use of induced pluripotent stem cell technologies in disease modeling of skeletal dysplasia2016
- Author(s)
  Noriyuki Tsumaki
- Organizer
  The 13th International Congress of Human Genetics (ICHG2016)
- Place of Presentation
  Kyoto
- Year and Date
  2016-04-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] 「iPS細胞を活用し身近な薬から創薬、可能性は」2016
- Author(s)
  妻木範行
- Organizer
  外交団セミナー「日本のiPS細胞、その最前線」
- Place of Presentation
  東京
- Year and Date
  2016-02-29
- Invited
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] iPS細胞技術を使った新たな軟骨疾患研究2016
- Author(s)
  妻木範行
- Organizer
  東京歯科大学大学院セミナー
- Place of Presentation
  東京都
- Year and Date
  2016-07-21
- Invited
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] iPS細胞研究の臨床応用2016
- Author(s)
  妻木範行
- Organizer
  ロート製薬株式会社　講演
- Place of Presentation
  京都府木津川市
- Year and Date
  2016-05-27
- Invited
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] 疾患iPS細胞モデルを使った骨系統疾患の治療薬の探索2016
- Author(s)
  妻木範行
- Organizer
  第50回日本小児内分泌学会学術集会［JSPE］第9回アジア太平洋小児内分泌学会［APPES］　総会
- Place of Presentation
  東京都
- Year and Date
  2016-11-17
- Invited
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] Establishment of a human growth plate model with iPS Cell-derived cartilage2016
- Author(s)
  木村武司、妻木範行
- Organizer
  第50回日本小児内分泌学会学術集会［JSPE］第9回アジア太平洋小児内分泌学会［APPES］　総会
- Place of Presentation
  東京都
- Year and Date
  2016-11-18
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] Application of iPS cell technologies to cartilage regeneration and disease modeling2016
- Author(s)
  Noriyuki Tsumaki
- Organizer
  The 3rd International Cartilage Repair Society (ICRS) Summit in collaboration with Osteoarthritis Research Society International (OARSI)
- Place of Presentation
  Kyoto
- Year and Date
  2016-04-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] SIK3経路阻害剤PterosinBは変形性関節症の進行を抑制する2016
- Author(s)
  箭原康人、妻木範行
- Organizer
  第10回骨・軟骨フロンティア
- Place of Presentation
  東京都
- Year and Date
  2016-11-05
- Invited
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] iPS細胞を使った軟骨疾患研究の新展開2016
- Author(s)
  妻木範行
- Organizer
  昭和大学歯学部口腔生化学講座　セミナー
- Place of Presentation
  東京都
- Year and Date
  2016-07-07
- Invited
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] 選択的c-Fos/AP-1阻害薬によるマウスの椎間板変性抑制効果．2015
- Author(s)
  箭原康人，関　庄二，牧野紘士，塩沢俊一，妻木範行，木村友厚．
- Organizer
  第30回日本整形外科学会基礎学術集会
- Place of Presentation
  富山国際会議場、富山市民プラザ(富山市)
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-25462289
[Presentation] Statins in Achondroplasia Treatment2015
- Author(s)
  Noriyuki Tsumaki
- Organizer
  12th ISDS MEETING ISTANBUL 2015
- Place of Presentation
  Istanbul,Turkey
- Year and Date
  2015-07-29
- Invited
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] iPS細胞モデルによる骨系統疾患の病態解明と創薬2015
- Author(s)
  妻木範行
- Organizer
  第2回大阪骨関節コロキウム
- Place of Presentation
  大阪府
- Year and Date
  2015-06-01
- Invited
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] 変形性関節症性変化におけるSik3の役割．2015
- Author(s)
  箭原康人，木村友厚，妻木範行．
- Organizer
  第30回日本整形外科学会基礎学術集会
- Place of Presentation
  富山国際会議場、富山市民プラザ(富山市)
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-25462289
[Presentation] iPS 細胞モデル研究による骨系統疾患の病態解明と創薬2015
- Author(s)
  妻木範行
- Organizer
  第118回日本小児科学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2015-04-17
- Invited
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] ｉＰＳ細胞を使った軟骨疾患の新しい研究方法2015
- Author(s)
  妻木範行
- Organizer
  第３１回つくしんぼ総会
- Place of Presentation
  大阪
- Year and Date
  2015-04-29
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] 第22回HAB研究機構学術年会2015
- Author(s)
  妻木範行
- Organizer
  骨系統疾患由来iPS細胞を用いた創薬研究
- Place of Presentation
  東京
- Year and Date
  2015-06-26
- Invited
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] iPS細胞モデルによる骨系統疾患の病態解明と創薬2015
- Author(s)
  妻木範行
- Organizer
  CBI学会2015
- Place of Presentation
  東京
- Year and Date
  2015-10-27
- Invited
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] FGFR3 軟骨形成異常症と疾患iPS 細胞モデル研究2015
- Author(s)
  妻木範行
- Organizer
  第26回日本小児整形外科学会学術集会
- Place of Presentation
  岐阜
- Year and Date
  2015-12-04
- Invited
- Data Source
  KAKENHI-PROJECT-15H02561
[Presentation] Ⅱ型コラーゲン病モデルの解析2014
- Author(s)
  岡田稔、妻木範行
- Organizer
  ＢＭＰ研究会
- Place of Presentation
  大阪
- Year and Date
  2014-07-28
- Data Source
  KAKENHI-PROJECT-24390354
[Presentation] ヒト皮膚線維芽細胞からの軟骨細胞様細胞誘導2014
- Author(s)
  王谷英達、岡田稔、山下晃弘、吉川秀樹、妻木範行
- Organizer
  第２７回日本軟骨代謝学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24390354
[Presentation] 「Conversion of fibroblasts into chondrocytes by cell reprogramming technologies」2014
- Author(s)
  Noriyuki Tsumaki
- Organizer
  Asian Cartilage Repair Society
- Place of Presentation
  Seoul,Korea
- Year and Date
  2014-12-07
- Invited
- Data Source
  KAKENHI-PROJECT-24390354
[Presentation] iPS細胞とダイレクト・リプログラミングを用いた2014
- Author(s)
  妻木範行
- Organizer
  第１３回日本再生医療学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24390354
[Presentation] 軟骨細胞リプログラミングと軟骨再生2013
- Author(s)
  妻木範行
- Organizer
  第44回広島整形外科先端医学セミナー
- Place of Presentation
  広島
- Invited
- Data Source
  KAKENHI-PROJECT-24390354
[Presentation] 細胞のタイプを変える-いくつになっても走れるのか?2013
- Author(s)
  妻木範行
- Organizer
  富田林高校出前授業
- Place of Presentation
  富田林(招待講演)
- Year and Date
  2013-02-01
- Data Source
  KAKENHI-PROJECT-24390354
[Presentation] iPS細胞とダイレクト・リプログラミングを用いた2013
- Author(s)
  妻木範行
- Organizer
  日本炎症・再生学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24390354
[Presentation] Chondrogenic differentiation of human induced pluripotent stem cells2012
- Author(s)
  Okada, M. ; Tsumaki, N
- Organizer
  International Society for Stem Cell Research 10th annual meeting
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-24390354
[Presentation] 軟骨細胞分化制御と再生医療における軟骨細胞ソースの開発2012
- Author(s)
  妻木範行
- Organizer
  骨代謝セミナー
- Place of Presentation
  東京(招待講演)
- Year and Date
  2012-12-21
- Data Source
  KAKENHI-PROJECT-24390354
[Presentation] 軟骨細胞増殖・分化に及ぼすCyp26bl遺伝子の機能の解析2012
- Author(s)
  峯岸芳樹、吉川秀樹、妻木範行
- Organizer
  第30回日本骨代謝学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24390354
[Presentation] 細胞リプログラミング技術による軟骨疾患治療2012
- Author(s)
  妻木範行
- Organizer
  日本整形外科学会基礎学術集会シンポジウム
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24390354
[Presentation] カレントコンセプト:軟骨細胞リプログラミングによる関節軟骨疾患の治療戦略2012
- Author(s)
  妻木範行
- Organizer
  第30回日本骨代謝学会
- Place of Presentation
  東京(招待講演)
- Data Source
  KAKENHI-PROJECT-24390354
[Presentation] 再生医療の最前線～軟骨疾患をターゲットとして2012
- Author(s)
  妻木範行
- Organizer
  第176回医学セミナー
- Place of Presentation
  藤田保健衛生大学(愛知)(招待講演)
- Year and Date
  2012-10-03
- Data Source
  KAKENHI-PROJECT-24390354
[Presentation] 再生医療の最前線-軟骨疾患をターゲットとして2012
- Author(s)
  妻木範行
- Organizer
  第46回日本小児内分泌学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24390354
[Presentation] 皮膚細胞培養から軟骨を作る試み2012
- Author(s)
  妻木範行
- Organizer
  第54回日本老年医学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24390354
[Presentation] Meet the Expert: 軟骨マトリックス転写活性を指標にした、細胞リプログラミングによる2012
- Author(s)
  妻木範行
- Organizer
  第30回日本骨代謝学会
- Place of Presentation
  東京(招待講演)
- Data Source
  KAKENHI-PROJECT-24390354
[Presentation] 軟骨細胞分化制御と細胞リプログラミング2012
- Author(s)
  妻木範行
- Organizer
  第7回岡山骨・関節セミナー
- Place of Presentation
  岡山(招待講演)
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-24390354
[Presentation] Generation of induced chondrogenic cells directly from dermal fibroblast culture by defined factors2012
- Author(s)
  Noriyuki Tsumaki
- Organizer
  Internatinal Conference on Bone Morphogenetic Protein
- Place of Presentation
  Lake Tahoe, CA, USA
- Data Source
  KAKENHI-PROJECT-24390354
[Presentation] Roles of Cyp26bl in endochondral bone formation2012
- Author(s)
  Minegishi, Y. Sakai, Y. Hosokawa, K. ;Yoshikawa, H. I Tsumaki, N
- Organizer
  Cold Spring Harbor Asia Conference, Bone and Cartilage
- Place of Presentation
  Suzhou Dushu, China
- Data Source
  KAKENHI-PROJECT-24390354
[Presentation] 細胞リプログラミングによる軟骨疾患治療と再生2012
- Author(s)
  妻木範行
- Organizer
  第40回日本関節病学会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-24390354
[Presentation] 皮膚線維芽細胞から軟骨細胞様細胞へのダイレクト・リプログラミング2012
- Author(s)
  妻木範行
- Organizer
  第33回日本炎症・再生医学会
- Place of Presentation
  博多
- Data Source
  KAKENHI-PROJECT-24390354
[Presentation] Regulation of differentiation and cell reprogramming of chondrocytes2012
- Author(s)
  Noriyuki Tsumaki
- Organizer
  Cold Spring Harbor Asia Conference, Bone and Cartilage
- Place of Presentation
  Suzhou Dushu, China
- Data Source
  KAKENHI-PROJECT-24390354
[Presentation] 細胞リプログラミング技術を用いたII型コラーゲン病疾患モデルの解析2012
- Author(s)
  岡田稔、妻木範行
- Organizer
  第9回Skeletal Research Meeting
- Place of Presentation
  京都
- Year and Date
  2012-11-10
- Data Source
  KAKENHI-PROJECT-24390354
[Presentation] 細胞リプログラミング技術を用いた軟骨疾患モデリング2012
- Author(s)
  岡田稔、妻木範行
- Organizer
  第5回胎児骨系統疾患フォーラム
- Place of Presentation
  仙台
- Year and Date
  2012-12-02
- Data Source
  KAKENHI-PROJECT-24390354
[Presentation] 細胞リプログラミングと軟骨疾患の再生2012
- Author(s)
  妻木範行
- Organizer
  第2回細胞再生医療研究会
- Place of Presentation
  神戸(招待講演)
- Year and Date
  2012-07-29
- Data Source
  KAKENHI-PROJECT-24390354
[Presentation] 軟骨細胞リプログラミングと軟骨マトリックス遺伝子発現2011
- Author(s)
  妻木範行
- Organizer
  日本整形外科学会基礎学術集会
- Place of Presentation
  群馬、前橋市
- Data Source
  KAKENHI-PROJECT-21390421
[Presentation] Directed inductionof hyaline chondrogenic cells frommouse adult dermal fibroblast cluturteby defined factors2011
- Author(s)
  Noriyuki Tsumaki
- Organizer
  Korean Society OfOsteoporosis
- Place of Presentation
  Seoul,Korea
- Data Source
  KAKENHI-PROJECT-21390421
[Presentation] Directed induction of chondrogenic cells from mouse dermal fibroblast culture2011
- Author(s)
  Noriyuki Tsumaki
- Organizer
  1st Bio-Rheumatology International
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-21390421
[Presentation] 皮膚細胞からの軟骨細胞誘導2011
- Author(s)
  平松久仁彦、笹川覚、玉山英達、中川加奈子、吉川秀樹、妻木範行
- Organizer
  第29回日本骨代謝学会学術集会
- Place of Presentation
  大阪、大阪市
- Data Source
  KAKENHI-PROJECT-21390421
[Presentation] Directed induction of hyaline chondrogenic cells from mouse adult dermal fibroblast cluturte by defined factors2011
- Author(s)
  Noriyuki Tsumaki
- Organizer
  Korean Society Of Osteoporosis
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-21390421
[Presentation] Directed inductionof chondrogenic cells from mousedermal fibroblast culture2011
- Author(s)
  Noriyuki Tsumaki
- Organizer
  1st BioRheumatology International
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21390421
[Presentation] 内軟骨性骨化におけるCyp261の役割の解析2011
- Author(s)
  峯岸芳樹、坂井靖夫、細川亙、吉川秀樹、妻木範行
- Organizer
  第12回運動器科学研究会
- Place of Presentation
  高知
- Year and Date
  2011-09-03
- Data Source
  KAKENHI-PROJECT-21390421
[Presentation] 軟骨コラーゲン転写制御と軟骨代謝2010
- Author(s)
  妻木範行
- Organizer
  第28回日本骨代謝学会
- Place of Presentation
  東京
- Year and Date
  2010-07-21
- Data Source
  KAKENHI-PROJECT-21390421
[Presentation] Regulatory sequences ofthe a2(XI) collgen chain gene andchondrogenesis2009
- Author(s)
  妻木範行
- Organizer
  6th Meeting of BoneBiology Forum
- Place of Presentation
  静岡市
- Year and Date
  2009-08-21
- Data Source
  KAKENHI-PROJECT-21390421
[Presentation] Regulatory sequences of the a2 (XI) collgen chain gene and chondrogenesis2009
- Author(s)
  妻木範行
- Organizer
  6^<th> Meeting of Bone Biology Forum
- Place of Presentation
  静岡
- Year and Date
  2009-08-21
- Data Source
  KAKENHI-PROJECT-21390421
[Presentation] XI型コラーゲン遺会子転写活性と軟骨分化/軟骨再生2009
- Author(s)
  妻木範行
- Organizer
  8^<th> Japan conference on Bone and Joint Diseases
- Place of Presentation
  東京
- Year and Date
  2009-01-23
- Data Source
  KAKENHI-PROJECT-21390421
[Presentation] Expression of dominant negative TGFβ receptors resulted information of hypoplastic cartilage in conditional transgenic mice2008
- Author(s)
  K. Hiramatsu, T. Iwai, D, Ikegami, H. Yoshikawa, N. Tsumaki
- Organizer
  7^<th> International Conference on Bone Morphogenetic Proteins
- Place of Presentation
  Lake Tahoe, CA. USA
- Data Source
  KAKENHI-PROJECT-18390415
[Presentation] Smad7 inhibits chondrocyte differentiation at multiplesteps dur ing endochondra1 bone formation.2008
- Author(s)
  T. Iwai, J. Murai, K. Hiramatsu, D. Ikegami, M. Okamoto, H. Yoshikawa, N. Tsumaki
- Organizer
  7^<th> International Conference on Bone Morphogenetic Proteins
- Place of Presentation
  Lake Tahoe, CA, USA
- Data Source
  KAKENHI-PROJECT-19659378
[Presentation] Smad7 inhibits chondrocyte differentiation at multiple steps during endochondral bone formation.2008
- Author(s)
  T. Iwai, J. Murai, K. Hiramatsu, D. Ikegami, M. Okamoto, H. Yoshikawa, N. Tsumaki
- Organizer
  7^<th> Ihternational Conference on Bone Morphogenetic Proteins
- Place of Presentation
  Lake Tahoe, CA, USA
- Data Source
  KAKENHI-PROJECT-18390415
[Presentation] 内軟骨性骨化におけるBMPシグナルの作用2007
- Author(s)
  妻木範行
- Organizer
  第14回BMP研究会
- Place of Presentation
  大阪
- Year and Date
  2007-07-22
- Data Source
  KAKENHI-PROJECT-19659378
[Presentation] Col11a2/Rxrbローカスにおける軟骨特異的転写の制御2007
- Author(s)
  村井純子、岡本美奈、吉川秀樹、妻木範行
- Organizer
  第1回骨・軟骨フロンティア
- Place of Presentation
  東京
- Year and Date
  2007-12-01
- Data Source
  KAKENHI-PROJECT-18390415
[Presentation] Role of Smad7 during endochondral bone formation.2007
- Author(s)
  T. Iwai, J. Murai, H. Yoshikawa, N. Tsumaki
- Organizer
  Gordon Research Conference
- Place of Presentation
  Cartilage Biology & Pathology, Ventura, CA USA
- Data Source
  KAKENHI-PROJECT-18390415
[Presentation] 内軟骨性骨化とBMPシグナル2007
- Author(s)
  妻木範行
- Organizer
  松本ボーンフォーラム
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-19659378
[Presentation] Function of the CTCF-bindig site between the Rxrb and the Col11a2 Genes2007
- Author(s)
  J. Murai, M, Okamoto, H. Yoshikawa, N. Tsumaki
- Organizer
  29th Annual Meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  Honolulu, Hawaii, USA
- Data Source
  KAKENHI-PROJECT-18390415
[Presentation] In vivoでのRxrb/Col11a2 locusにおけるCTCF結合領域の機能解析2007
- Author(s)
  村井純子、岡本美奈、吉川秀樹、妻木範行
- Organizer
  第25回日本骨代謝学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-18390415
[Presentation] 内軟骨性骨化におけるBMPシグナルの作用2007
- Author(s)
  妻木範行
- Organizer
  第14回BMP研究会
- Place of Presentation
  大阪
- Year and Date
  2007-07-22
- Data Source
  KAKENHI-PROJECT-18390415
[Presentation] Role of Smad7 during endochondral bone formation2007
- Author(s)
  T. Iwai, J. Murai, H. Yoshikawa, N. Tsumaki
- Organizer
  Gordon Research Conference, Cartilage Biology & Pathology, Ventura
- Place of Presentation
  CA USA
- Data Source
  KAKENHI-PROJECT-18390415
[Presentation] Inhibitory Smad6 and Smad7 Differently Regulate Cartilage Formation2007
- Author(s)
  T. Iwai, J. Murai, H. Yoshikawa, N. Tsumaki
- Organizer
  29th Annual Meeting of the American Society for Bone and Mineral Resarch
- Place of Presentation
  Honolulu, Hawaii, USA
- Data Source
  KAKENHI-PROJECT-19659378
[Presentation] iPS細胞技術を使った軟骨再生
- Author(s)
  妻木範行
- Organizer
  第35回日本炎症・再生医学会
- Place of Presentation
  沖縄
- Year and Date
  2014-07-02 – 2014-07-04
- Data Source
  KAKENHI-PROJECT-24390354
[Presentation] Cartilage Regeneration with iPS Cell Technologies
- Author(s)
  Noriyuki Tsumaki
- Organizer
  The 5th Tissue Engineering Symposium
- Place of Presentation
  Sydney,Australia
- Year and Date
  2014-08-18 – 2014-08-20
- Data Source
  KAKENHI-PROJECT-24390354
[Presentation] DERIVATION OF TRANSPLANTABLE CARTILAGE FROM HUMAN INDUCED PLURIPOTENT STEM CELLS
- Author(s)
  A. Yamashita, M. Morioka, Y. Yahara, M. Okada, N. Tsumaki
- Organizer
  2014 OARSI
- Place of Presentation
  Paris,France
- Year and Date
  2014-04-24 – 2014-04-27
- Data Source
  KAKENHI-PROJECT-24390354
[Presentation] 細胞リプログラミング技術を使った軟骨疾患研究
- Author(s)
  妻木範行
- Organizer
  第29回日本整形外科学会基礎学術集会
- Place of Presentation
  鹿児島
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-24390354
[Presentation] Application of iPSC technology to cartilage regeneration and disease modelling
- Author(s)
  Noriyuki Tsumaki
- Organizer
  Croucher Foundation Advanced Study Institute (ASI)： “Stem Cells: Biology & Applications”
- Place of Presentation
  Hong Kong
- Year and Date
  2015-01-05 – 2015-01-07
- Invited
- Data Source
  KAKENHI-PROJECT-24390354
[]

1. YOSIKAWA Hideki (60191558)

# of Collaborated Projects: 7 results

# of Collaborated Products: 62 results
2. MYOUI Akira (10263261)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
3. SUGANO Nobuhiko (70273620)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. FUJITA Kaori (10633092)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 岡本美奈 (50457008)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
6. YAMAMOTO KOJI (70536565)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. AKIYAMA Haruhiko (60402830)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TOMITA Tetsuya (30283766)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SUGAMOTO Kazuomi (40294061)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. UEDA Takafumi (00324773)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. Seki Shoji (00432112)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. KAWAGUCHI YOSHIHARU (00262527)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. MOTOMURA HIRAKU (50640827)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. OHTA Akira (00168931)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. Ozono Keiichi (20270770)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 道上敏美 (00301804)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. YAMASHITA Akihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. TAMAMURA Yoshihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. WATANABE Akira

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 木村友厚

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 阿部訓也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 千々松良太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 中村博亮

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tsumaki Noriyuki 妻木 範行

TSUMAKI Noriyuki 妻木 範行

妻木 範行 ツマキ ノリユキ

Research Projects

Research Products

Co-Researchers

シングルセル網羅的発現解析とiPS細胞モデルによるヒト軟骨分化機構の解明Principal Investigator

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Analysis of regulatory mechanisms for differentiation of human cartilage tissuePrincipal Investigator

Principal Investigator

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Review Section

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Principal Investigator

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Review Section

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Analysis of regulation of chondrocyte differentiation by SIK3 and lipid metabolismPrincipal Investigator

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Principal Investigator

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Principal Investigator

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Principal Investigator

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Principal Investigator

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Analysis of regulatory mechanisms controlling proliferation and differentiation of chondrocytesPrincipal Investigator

Principal Investigator

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Analysis of BMP-mediated cartilage formation anddifferentiation, and cartilage repairPrincipal Investigator

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Principal Investigator

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脂肪細胞から核の初期化を経て誘導した軟骨細胞による軟骨修復Principal Investigator

Principal Investigator

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Research Institution

Analysis of cartilage formation and differentiation through regulation of chondrocyte signaling and transcription of matrix genesPrincipal Investigator

Principal Investigator

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Research Institution

超音波刺激,人工骨,骨形成因子(BMP)シグナル操作を組み合わせた骨欠損の修復Principal Investigator

Principal Investigator

Tsumaki Noriyuki 妻木範行

TSUMAKI Noriyuki 妻木範行

妻木範行ツマキノリユキ

[Book] 実践医学増刊「オルガノイドがもたらすライフサイエンス革命」2024

[Book] 標準整形外科学　第15版2023

[Book] 学術定期雑誌「HORMONE　FRONTIER　IN　GYNECOLOGY」第117号2023