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Doi Nobuhide  土居 信英

ORCIDConnect your ORCID iD *help
… Alternative Names

DOI Nobuhide  土居 信英

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Researcher Number 50327673
Other IDs
External Links
Affiliation (Current) 2025: 慶應義塾大学, 理工学部(矢上), 教授
Affiliation (based on the past Project Information) *help 2017 – 2024: 慶應義塾大学, 理工学部(矢上), 教授
2016: 慶應義塾大学, 理工学部(矢上), 准教授
2010 – 2015: 慶應義塾大学, 理工学部, 准教授
2014: 慶應義塾大学, 理工学部生命情報学科, 准教授
2008: Keio University, 理工学部, 准教授 … More
2005 – 2007: 慶應義塾大学, 理工学部, 講師
2004: 慶應義塾大学, 理工学部, 専任講師
2002: Fac. Sci. & Tech., Assistant Professor, 理工学部, 講師
2001 – 2002: 慶應義塾大学, 理工学部, 助手 Less
Review Section/Research Field
Principal Investigator
Biofunction/Bioprocess / Biological Sciences / Biomedical engineering/Biomaterial science and engineering / Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 90120:Biomaterials-related / Applied genomics / Biofunction/Bioprocess / Applied molecular and cellular biology / Evolutionary biology / Applied molecular and cellular biology … More
Except Principal Investigator
… More Medium-sized Section 53:Organ-based internal medicine and related fields / Basic Section 53010:Gastroenterology-related / Gastroenterology / Applied genomics / 広領域 / Neurochemistry/Neuropharmacology Less
Keywords
Principal Investigator
蛋白質 / バイオテクノロジー / 進化 / 共焦点顕微鏡 / プロテオーム / 核酸 / 発現制御 / 免疫学 / 癌 / 生体生命情報学 … More / ドラッグデリバリーシステム / ウイルス / 試験管内選択 / 試験管内進化 / ライブラリー / 細胞膜透過 / ペプチド / 抗体 / 中分子医薬 / 細胞内抗体医薬 / pH応答性一本鎖抗体 / mRNAディスプレイ / 免疫原性 / 膜融合ペプチド / Escherichia coli / Bioinformatics / Gene network / Protein-protein interaction / Fluorescence labeling / Bacterial genome / Microarrays / Proteome / 大腸菌 / バイオインフォマティクス / マイロクアレイ / 遺伝子ネットワーク / タンパク質間相互作用 / 蛍光ラベル化法 / 微生物ゲノム / マイクロアレイ / がん / マイクロ・ナノデバイス / 電気材料 / バイオマス / 酵素 / 遺伝子 / 配列空間 / mRNAディスプレイ法 / 遺伝暗号 / 合成生物学 / 生命の起源 / ライプラリー / RNAディスプレイ法 / DNAディスプレイ法 / Fab抗体 / 一本鎖抗体 / 抗体医薬 / 組み換え抗体 / 生物機能工学 / バイオセンサー / 遺伝子工学 / タンパク質工学 / 進化分子工学 … More
Except Principal Investigator
CD44 / がん幹細胞 / CAPZA1 / オートファジー / H. pylori / 癌幹細胞 / Proteome / プロテオーム / 線維化 / 肝再生 / Sema6A / 類洞内皮細胞 / 肝微小環境 / ムコソイド / 糖鎖 / 遺伝子デリバリー / ペプチド抗体 / 胃内共生細菌 / mucosoid / 胃がん幹細胞 / MnSOD / autophagy / 抗体 / 酸化ストレス / 膜透過性ペプチド / 低分子抗体 / ペプチド / CagA / 膜透過促進ペプチド / 一本鎖抗 / CD44v9 / High-throughput screening / Bioinformatics / Gene network / Protein-protein interactions / In vitro virus / Disease-related genes / Alternative splicing / 蛋白質間相互作用 / ハイスループットスクリーニング / バイオインフォマティクス / 遺伝子ネットワーク / タンパク質間相互作用 / In vitro virus法 / 疾患遺伝子 / 選択的スプライシング / Puromycin / Interaction / Fluorescence Labeling / Protein Chip / Micro array / Proteomics / ピューロマイシン / 相互作用 / 蛍光ラベル / プロテインチップ / マイクロアレイ / プロテオミクス / 再生医学 / 幹細胞 / 分化 / Dcx / Dcc / Musashi / 神経分化 / 転写後制御 / 翻訳制御 / 未分化維持 / 神経回路 / 神経発生 / RNA結合タンパク質 / Musashi1 Less
  • Research Projects

    (20 results)
  • Research Products

    (111 results)
  • Co-Researchers

    (27 People)
  •  感染症の標的となる細胞内因子に対するバイオ医薬の創出・送達技術の開発Principal Investigator

    • Principal Investigator
      土居 信英
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      Keio University
  •  肝微小環境の構造理解に基づく新たな代謝性肝疾患治療の確立

    • Principal Investigator
      本多 政夫
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 53:Organ-based internal medicine and related fields
    • Research Institution
      Kanazawa University
  •  Development of a two-step molecular targeted therapy to eliminate gastric cancer stem cells and progenitor cells

    • Principal Investigator
      Suzuki Hidekazu
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Tokai University
  •  Development of cancer cell-selective membrane-permeable antibodies against intracellular disease targetsPrincipal Investigator

    • Principal Investigator
      Doi Nobuhide
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 90120:Biomaterials-related
    • Research Institution
      Keio University
  •  mRNAディスプレイ法による翻訳アレスト配列の大規模探索Principal Investigator

    • Principal Investigator
      土居 信英
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Keio University
  •  Development of cell-specific DDS for biopharmaceuticals using a novel human-derived membrane penetration-enhancing peptidePrincipal Investigator

    • Principal Investigator
      DOI Nobuhide
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Keio University
  •  Mandatory autophagy induction targeting gastric cancer stem cells by hybrid small molecule antibodies

    • Principal Investigator
      SUZUKI HIDEKAZU
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  Fusogenic peptides combined with pH-dependent antibody fragments for cell-specific intracellular drug deliveryPrincipal Investigator

    • Principal Investigator
      DOI Nobuhide
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Keio University
  •  mRNAディスプレイ法による翻訳アレスト配列探索技術の開発Principal Investigator

    • Principal Investigator
      土居 信英
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Keio University
  •  Cell-free display technologies for development of next-generation therapeutic antibody fragmentsPrincipal Investigator

    • Principal Investigator
      DOI NOBUHIDE
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biofunction/Bioprocess
    • Research Institution
      Keio University
  •  Analysis for a neural differentiation regulatory factor, Musashi1

    • Principal Investigator
      HORISAWA Kenichi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Kyushu University
      Keio University
  •  Development of an efficient screening technique for oxidoreductases used for biofuel cellsPrincipal Investigator

    • Principal Investigator
      DOI Nobuhide
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Biofunction/Bioprocess
    • Research Institution
      Keio University
  •  Cell-free display technology for optimization of antibody drugsPrincipal Investigator

    • Principal Investigator
      DOI Nobuhide
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biofunction/Bioprocess
    • Research Institution
      Keio University
  •  On-Chip Co-expression Microarrays for Precise Analysis of Transcriptional Regulatory NetworksPrincipal Investigator

    • Principal Investigator
      DOI Nobuhide
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Applied molecular and cellular biology
    • Research Institution
      Keio University
  •  In vitro selection of novel recombinant antibodiesPrincipal Investigator

    • Principal Investigator
      DOI Nobuhide
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biofunction/Bioprocess
    • Research Institution
      Keio University
  •  限定されたアミノ酸からなるランダム配列タンパク質の機能探索Principal Investigator

    • Principal Investigator
      土居 信英
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Evolutionary biology
    • Research Institution
      Keio University
  •  A large-scale analysis of protein-protein interactions using Escherichia coli proteome chipsPrincipal Investigator

    • Principal Investigator
      DOI Nobuhide
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Applied genomics
    • Research Institution
      Keio University
  •  Proteome Analysis of Disease-related Genes based on Alternative Splicing

    • Principal Investigator
      YANAGAWA Hiroshi
    • Project Period (FY)
      2004 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Applied genomics
    • Research Institution
      Keio University
  •  進化分子工学によるエストロゲン様物質センサータンパク質の創出Principal Investigator

    • Principal Investigator
      土居 信英
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Applied molecular and cellular biology
    • Research Institution
      Keio University
  •  Protein Microarrays based on C-terminal Labeling of Proteins

    • Principal Investigator
      YANAGAWA Hiroishi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      広領域
    • Research Institution
      Keio University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007

All Journal Article Presentation Book Patent

  • [Book] ドラッグデリバリーシステム - バイオ医薬品創成に向けた組織、細胞内、核内送達技術の開発-2018

    • Author(s)
      土居信英
    • Total Pages
      280
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-17H02103
  • [Book] 医療・診断をささえるペプチド科学 - 再生医療・DDS・診断への応用 -2017

    • Author(s)
      土居信英
    • Total Pages
      7
    • Publisher
      シーエムシー出版
    • ISBN
      9784781312675
    • Data Source
      KAKENHI-PROJECT-17H02103
  • [Book] 進化分子工学 ~高速分子進化によるタンパク質・核酸の開発~2013

    • Author(s)
      土居信英
    • Total Pages
      12
    • Publisher
      NTS出版
    • Data Source
      KAKENHI-PROJECT-24656508
  • [Book] 進化分子工学による新規タンパク質の創出とプロテオミクスへの応用.「進化分子工学~高速分子進化によるタンパク質・核酸の開発~」(伏見譲編)2013

    • Author(s)
      土居信英,柳川弘志
    • Publisher
      NTS出版
    • Data Source
      KAKENHI-PROJECT-24656508
  • [Book] 進化分子工学 ~高速分子進化によるタンパク質・核酸の開発~2013

    • Author(s)
      土居信英
    • Total Pages
      12
    • Publisher
      NTS出版
    • Data Source
      KAKENHI-PROJECT-25289298
  • [Book] 次世代医薬開発に向けた抗体工学の最前線2012

    • Author(s)
      土居信英
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-22360351
  • [Book] 現代生物科学入門9:合成生物学2010

    • Author(s)
      柳川弘志,土居信英
    • Publisher
      岩波書店
    • Data Source
      KAKENHI-PROJECT-22360351
  • [Book] 現代生物科学入門9:合成生物学2010

    • Author(s)
      土居信英
    • Total Pages
      220
    • Publisher
      岩波書店
    • Data Source
      KAKENHI-PROJECT-22360351
  • [Journal Article] Guanine nucleotide exchange factor DOCK11-binding peptide fused with a single chain antibody inhibits Hepatitis B Virus infection and replication.2022

    • Author(s)
      Ide, M., Tabata, N., Yonemura, Y., Shirasaki, T., Murai, K., Wang, Y., Ishida, A., Okada, H., Honda, M., Kaneko, S., Doi, N., Ito, S., Yanagawa, H.
    • Journal Title

      Journal of Biological Chemistry

      Volume: 298 Issue: 7 Pages: 102097-102097

    • DOI

      10.1016/j.jbc.2022.102097

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H04535
  • [Journal Article] Cytoplasmic delivery of siRNA using human-derived membrane penetration-enhancing peptide.2022

    • Author(s)
      Nakamura, M., Fujiwara, K., Doi, N.
    • Journal Title

      Journal of Nanobiotechnology

      Volume: 20 Issue: 1 Pages: 458-458

    • DOI

      10.1186/s12951-022-01667-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H04535, KAKENHI-ORGANIZER-19H05794
  • [Journal Article] Characterization of the membrane penetration-enhancing peptide S19 derived from human syncytin-1 for the intracellular delivery of TAT-fused proteins2022

    • Author(s)
      Suzuki Mayuko、Iwaki Kouta、Kikuchi Moeki、Fujiwara Kei、Doi Nobuhide
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 586 Pages: 63-67

    • DOI

      10.1016/j.bbrc.2021.11.065

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H04823, KAKENHI-PROJECT-20H04535
  • [Journal Article] Microfluidic screening system based on boron-doped diamond electrodes and dielectrophoretic sorting for directed evolution of NAD(P)-dependent oxidoreductases.2020

    • Author(s)
      Goto, H., Kanai, Y., Yotsui, A., Shimokihara, S., Shitara, S., Oyobiki, R., Fujiwara, K., Watanabe, T., Einaga, Y., Matsumoto, Y., Miki, N., Doi, N.
    • Journal Title

      Lab Chip

      Volume: 20 Issue: 4 Pages: 852-861

    • DOI

      10.1039/c9lc01263j

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H02103
  • [Journal Article] Cell-sized confinement controls generation and stability of a protein wave for spatiotemporal regulation in cells2019

    • Author(s)
      Kohyama Shunshi、Yoshinaga Natsuhiko、Yanagisawa Miho、Fujiwara Kei、Doi Nobuhide
    • Journal Title

      eLife

      Volume: 8

    • DOI

      10.7554/elife.44591

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-18H04565, KAKENHI-PROJECT-17H00769, KAKENHI-PROJECT-17H02103, KAKENHI-PROJECT-17K05605, KAKENHI-PROJECT-18H01187
  • [Journal Article] Regulation of spatiotemporal patterning in artificial cells by a defined protein expression system2019

    • Author(s)
      Yoshida Aoi、Kohyama Shunshi、Fujiwara Kei、Nishikawa Saki、Doi Nobuhide
    • Journal Title

      Chemical Science

      Volume: 10 Issue: 48 Pages: 11064-11072

    • DOI

      10.1039/c9sc02441g

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-18H04565, KAKENHI-PROJECT-17H02103
  • [Journal Article] Engineering of DNA polymerase I from Thermus thermophilus using compartmentalized self-replication.2018

    • Author(s)
      Aye, S.L., Fujiwara, K., Ueki, A., Doi, N.
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 499 Issue: 2 Pages: 170-176

    • DOI

      10.1016/j.bbrc.2018.03.098

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H02103
  • [Journal Article] A dual system using compartmentalized partnered replication for selection of arsenic-responsive transcriptional regulator.2018

    • Author(s)
      Aye, S.L., Fujiwara, K., Doi, N.
    • Journal Title

      J. Biochem.

      Volume: 164 Issue: 5 Pages: 341-348

    • DOI

      10.1093/jb/mvy055

    • NAID

      40021724808

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H02103
  • [Journal Article] Artificial Cell Fermentation as a Platform for Highly Efficient Cascade Conversion2017

    • Author(s)
      Fujiwara Kei、Adachi Takuma、Doi Nobuhide
    • Journal Title

      ACS Syntheitc Biology

      Volume: 7 Issue: 2 Pages: 363-370

    • DOI

      10.1021/acssynbio.7b00365

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-17H05235, KAKENHI-PROJECT-17H02103
  • [Journal Article] ヒト由来膜融合ペプチドによるバイオ医薬のDDS.2017

    • Author(s)
      土居信英
    • Journal Title

      細胞

      Volume: 49 Pages: 602-605

    • Data Source
      KAKENHI-PROJECT-17H02103
  • [Journal Article] Human-derived fusogenic peptides for the intracellular delivery of proteins.2017

    • Author(s)
      Sudo, K., Niikura, K., Iwaki, K., Kohyama, S., Fujiwara, K., Doi, N.
    • Journal Title

      J. Control. Release

      Volume: 255 Pages: 1-11

    • DOI

      10.1016/j.jconrel.2017.03.398

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K12545, KAKENHI-PROJECT-17H02103
  • [Journal Article] In vitro transcription-translation using bacterial genome as a template to reconstitute intracellular profile2017

    • Author(s)
      Fujiwara Kei、Sawamura Tsunehito、Niwa Tatsuya、Deyama Tatsuki、Nomura Shin-ichiro M.、Taguchi Hideki、Doi Nobuhide
    • Journal Title

      Nucleic Acids Research

      Volume: 45 Issue: 19 Pages: 11449-11458

    • DOI

      10.1093/nar/gkx776

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-17H05235, KAKENHI-PUBLICLY-17H05674, KAKENHI-PROJECT-15H02774
  • [Journal Article] PURE mRNA display for in vitro selection of single-chain antibodies.2016

    • Author(s)
      Nagumo, Y., Fujiwara, K., Horisawa, K., Yanagawa, H., Doi, N.
    • Journal Title

      J. Biochem.

      Volume: 159 Issue: 5 Pages: 519-526

    • DOI

      10.1093/jb/mvv131

    • NAID

      40020833577

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K12545, KAKENHI-PROJECT-25289298, KAKENHI-PUBLICLY-15H01543
  • [Journal Article] Endosomal escape efficiency of fusogenic B18 and B55 peptides fused with anti-EGFR single chain Fv as estimated by nuclear translocation.2016

    • Author(s)
      Niikura, K., Horisawa, K., Doi, N.
    • Journal Title

      J. Biochem.

      Volume: 159 Issue: 1 Pages: 123-132

    • DOI

      10.1093/jb/mvv083

    • NAID

      40020725715

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K12545, KAKENHI-PROJECT-25289298
  • [Journal Article] Biochemical preparation of cell extract for cell-free protein synthesis without physical disruption2016

    • Author(s)
      K. Fujiwara, N. Doi
    • Journal Title

      PLOS ONE

      Volume: 11 Issue: 4 Pages: e0154614-e0154614

    • DOI

      10.1371/journal.pone.0154614

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-15H00826, KAKENHI-PUBLICLY-15H01543, KAKENHI-PROJECT-15K12545, KAKENHI-PROJECT-26650044
  • [Journal Article] In vitro selection of bispecific diabody fragments using covalent bicistronic DNA display.2016

    • Author(s)
      Nakayama, M., Komiya, S., Fujiwara, K., Horisawa, K., Doi, N.
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 478 Issue: 2 Pages: 606-611

    • DOI

      10.1016/j.bbrc.2016.07.113

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K12545, KAKENHI-PROJECT-16K08592
  • [Journal Article] A fusogenic peptide from a sea urchin fertilization protein promotes intracellular delivery of biomacromolecules by facilitating endosomal escape.2015

    • Author(s)
      Niikura, K., Horisawa, K., Doi, N.
    • Journal Title

      J. Control. Release

      Volume: 212 Pages: 85-93

    • DOI

      10.1016/j.jconrel.2015.06.020

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K12545, KAKENHI-PROJECT-25289298
  • [Journal Article] Structural basis for inhibition of the MDM2:p53 interaction by an optimized MDM2-binding peptide selected with mRNA display2014

    • Author(s)
      T. Nagata, K. Shirakawa, N. Kobayashi, H. Shiheido, N. Tabata, Y. Sakuma-Yonemura, K. Horisawa, M. Katahira, N. Doi, H. Yanagawa
    • Journal Title

      PLOS ONE

      Volume: 9 Issue: 10 Pages: e109163-e109163

    • DOI

      10.1371/journal.pone.0109163

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23570146, KAKENHI-PROJECT-25289298, KAKENHI-PROJECT-26440026
  • [Journal Article] MIP-2A is a novel target of an anilinoquinazoline derivative for inhibition of tumour cell proliferation.2013

    • Author(s)
      Tokunaga M, Shiheido H, Tabata N, Sakuma-Yonemura Y, Takashima H, Horisawa K, Doi N, Yanagawa H.
    • Journal Title

      PLoS One.

      Volume: 8 Issue: 9 Pages: e76774-e76774

    • DOI

      10.1371/journal.pone.0076774

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24500447
  • [Journal Article] Hereditary spastic paraplegia protein spartin is an FK506-binding protein identified by mRNA display.2013

    • Author(s)
      Tokunaga M, Shiheido H, Hayakawa I, Utsumi A, Takashima H, Doi N, Horisawa K, Sakuma-Yonemura Y, Tabata N, Yanagawa H.
    • Journal Title

      Chemistry & Biology

      Volume: 20 Issue: 7 Pages: 935-942

    • DOI

      10.1016/j.chembiol.2013.05.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24500447
  • [Journal Article] DNA display selection of peptide ligands for a full-length human G protein-coupled receptor on CHO-K1 cells2012

    • Author(s)
      Doi, N., Yamakawa, N., Matsumoto, H., Yamamoto, Y., Nagano, T., Matsumura, N., Horisawa, K., Yanagawa, H.
    • Journal Title

      PLoS ONE

      Volume: 7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22658111
  • [Journal Article] In vitro selection of Fab fragments by mRNA display and gene-linking emulsion PCR2012

    • Author(s)
      Sumida, T., Yanagawa, H., Doi, N
    • Journal Title

      J. Nucleic Acids

      Volume: 2012 Pages: 371379-371379

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22360351
  • [Journal Article] DNA display selection of peptide ligands for a full-length human G protein-coupled receptor on CHO-K1 cells2012

    • Author(s)
      Doi,N.,Yamakawa,N.,Matsumoto,H.,Yamamoto,Y.,Nagano,T.,Matsumura,N.,Horisawa,K.,Yanagawa,H
    • Journal Title

      PLoS ONE

      Volume: 7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22360351
  • [Journal Article] mRNA display selection of an optimized MDM2-binding peptide that potently inhibits MDM2-p53 interaction2011

    • Author(s)
      Shiheido, H., Takashima, H., Doi, N., Yanagawa, H
    • Journal Title

      PLoS ONE

      Volume: 6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22360351
  • [Journal Article] DNA display selection of peptide ligands for a full-length human G protein-coupled receptor on CHO-K1 cells2011

    • Author(s)
      Doi,N.,Yamakawa,N.,Matsumoto,H.,Yamamoto,Y.,Nagano,T.,Matsumura,N.,Horisawa,K.,Yanagawa,H.
    • Journal Title

      PLoS ONE

      Volume: 7 Issue: 1 Pages: 1-8

    • DOI

      10.1371/journal.pone.0030084

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310121, KAKENHI-PROJECT-22360351, KAKENHI-PROJECT-22658111, KAKENHI-PROJECT-23650271
  • [Journal Article] Comparison of the frequency of functional SH3 domains with different limited sets of amino acids using mRNA display2011

    • Author(s)
      Tanaka, J., Yanagawa, H., Doi, N
    • Journal Title

      PLoS ONE

      Volume: 6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22360351
  • [Journal Article] Comparative characteriza-tion of random-sequence proteins consisting of 5, 12 and 20 kinds of amino acids2010

    • Author(s)
      Tanaka, J., Doi, N., Takashima, H., Yanagawa, H
    • Journal Title

      Protein Sci

      Volume: 19 Pages: 786-795

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22360351
  • [Journal Article] mRNA display selection of a high-affinity, Bcl-XL-specific binding peptide2010

    • Author(s)
      Matsumura, N., Tsuji, T., Sumida, T., Kokubo, M., Onimaru, M., Doi, N., Takashima, H., Miyamoto-Sato, E., Yanagawa, H
    • Journal Title

      FASEB J

      Volume: 24 Pages: 2201-2210

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22360351
  • [Journal Article] Rapid antibody selection by mRNA display on a microfluidic chip2009

    • Author(s)
      Tabata, N., Sakuma, Y., Honda, Y., Doi, N., Takashima, H., Miyamoto-Sato, E., Yanagawa, H.
    • Journal Title

      Nucleic Acids Res. 37

      Pages: 64-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19360377
  • [Journal Article] Use of cDNA tiling arrays for identifying proteininteractions selected by in vitro display technologies2008

    • Author(s)
      Horisawa, K., Doi, N., Yanagawa, H.
    • Journal Title

      PLoS ONE 3

      Pages: 1646-1646

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19360377
  • [Journal Article] Photocleavable linkage between genotype and phenotype for rapid and efficient recovery of nucleic acids encoding affinity-selected proteins2007

    • Author(s)
      Doi, N., et. al.
    • Journal Title

      J. Biotechnol 131

      Pages: 231-239

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16201042
  • [Journal Article] Photocleavable linkage between genotype and phenotype for rapid and efficient recovery of nucleic acids encoding affinity-selected proteins2007

    • Author(s)
      Doi, N.
    • Journal Title

      J.Biotechnol. 131

      Pages: 231-239

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16201042
  • [Journal Article] Photocleavable linkage between genotype and phenotype for rapid and efcient recovery of nucleic acids encoding affinity-selected proteins2007

    • Author(s)
      Doi, N.
    • Journal Title

      J.Biotechnol 131

      Pages: 231-239

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16201042
  • [Journal Article] Photocleavable linkage between genotype and phenotype for rapid and efficient recovery of nucleic acids encoding affinity-selected proteins2007

    • Author(s)
      Doi, N.
    • Journal Title

      J.Biotechnol. 131

      Pages: 231-239

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19360377
  • [Journal Article] Photocleavable linkage between genotype and phenotype for rapid and efficient recovery of nucleic acids encoding affinity-selected proteins2007

    • Author(s)
      Doi, N., Takashima, H., Wada, A., Oishi, Y., Nagano, T., Yanagawa, H.
    • Journal Title

      J. Biotechnol. 131

      Pages: 231-239

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19360377
  • [Journal Article] Photocleavable linkage between genotype and phenotype for rapid and efficient recovery of nucleic acids encoding affinity-selected Proteins2007

    • Author(s)
      Doi, N.
    • Journal Title

      J.Biotechnol. 131

      Pages: 231-239

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19657073
  • [Journal Article] High-throughput fluorescence labeling of full-length cDNA products based on a reconstituted translation system2007

    • Author(s)
      Kawahashi, Y., Doi, N., Oishi, Y., Tsuda, C., Takashima, H., Baba, T., Mori, H., Ito, T., Yanagawa, H.
    • Journal Title

      J. Biochem. 141

      Pages: 19-24

    • NAID

      10020101733

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19360377
  • [Patent] 融合タンパク質又は複合タンパク質,細胞内送達用担体,部分ペプチド,細胞膜透過促進剤,DNA,及びベクター2015

    • Inventor(s)
      須藤慧,新倉啓介,土居信英
    • Industrial Property Rights Holder
      学校法人慶應義塾
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015-06-11
    • Data Source
      KAKENHI-PROJECT-15K12545
  • [Patent] 融合タンパク質又は複合タンパク質,細胞内送達用担体,部分ペプチド,細胞膜透過促進剤,DNA,及びベクター2015

    • Inventor(s)
      須藤慧,新倉啓介,土居信英
    • Industrial Property Rights Holder
      学校法人慶應義塾
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015-06-11
    • Data Source
      KAKENHI-PROJECT-25289298
  • [Presentation] ヒトCD9由来細胞透過性ペプチドC21の変異解析2023

    • Author(s)
      横井太河,久米野康紘,藤原慶,土居信英
    • Organizer
      第39回日本DDS学会学術集会(千葉)
    • Data Source
      KAKENHI-PROJECT-23H00554
  • [Presentation] 核内の疾患標的に対するヒトVH単一ドメイン抗体の創出および送達2023

    • Author(s)
      松本朋子,加藤里花子,漆島穣一,藤原慶,土居信英
    • Organizer
      第39回日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-21H04823
  • [Presentation] 肝線維化を抑制するリード抗体のmRNAディスプレイ法による創出2023

    • Author(s)
      永渕泰平,加藤里花子,藤原慶,岡田光,本多政夫,土居信英
    • Organizer
      第2回日本抗体学会
    • Data Source
      KAKENHI-PROJECT-21H04823
  • [Presentation] ヒトSyncytin1由来膜透過促進ペプチドを用いた肝細胞選択的なタンパク質の細胞質送達2023

    • Author(s)
      清野真梨子,藤原慶,土居信英
    • Organizer
      第39回日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-21H04823
  • [Presentation] ヒトCD9由来細胞透過性ペプチドC21の変異解析2023

    • Author(s)
      横井太河,久米野康紘,藤原慶,土居信英
    • Organizer
      第39回日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-21H04823
  • [Presentation] 核内の疾患標的に対するヒトVH単一ドメイン抗体の創出および送達2023

    • Author(s)
      松本朋子,加藤里花子,漆島穣一,藤原慶,土居信英
    • Organizer
      第39回日本DDS学会学術集会(千葉)
    • Data Source
      KAKENHI-PROJECT-23H00554
  • [Presentation] 肝線維化を抑制するリード抗体のmRNAディスプレイ法による創出2023

    • Author(s)
      永渕泰平,加藤里花子,藤原慶,岡田光,本多政夫,土居信英
    • Organizer
      第2回日本抗体学会(鹿児島)
    • Data Source
      KAKENHI-PROJECT-23H00554
  • [Presentation] ヒトSyncytin1由来膜透過促進ペプチドを用いた肝細胞選択的なタンパク質の細胞質送達2023

    • Author(s)
      清野真梨子,藤原慶,土居信英
    • Organizer
      第39回日本DDS学会学術集会(千葉)
    • Data Source
      KAKENHI-PROJECT-23H00554
  • [Presentation] PURE mRNAディスプレイ法によるアクチンキャップタンパク質CAPZA1に結合するヒト単一ドメイン抗体の試験管内選択2022

    • Author(s)
      野崎智嗣,津川仁,鈴木秀和,藤原慶,土居信英
    • Organizer
      第45回日本分子生物学会年会(幕張メッセ)
    • Data Source
      KAKENHI-PROJECT-20H04535
  • [Presentation] PURE mRNAディスプレイ法によるヒトVH単一ドメイン抗体ライブラリーの試験管内選択2022

    • Author(s)
      加藤里花子,藤原慶,土居信英
    • Organizer
      第45回日本分子生物学会年会(幕張メッセ)
    • Data Source
      KAKENHI-PROJECT-20H04535
  • [Presentation] がん細胞選択的DDSに向けたEGFRに対する環境応答性単一ドメイン抗体の創出2021

    • Author(s)
      明石尚之,清野真梨子,藤原慶,土居信英
    • Organizer
      第44回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-21H04823
  • [Presentation] がん細胞選択的DDSに向けたEGFRに対する環境応答性単一ドメイン抗体の創出2021

    • Author(s)
      明石尚之,清野真梨子,藤原慶,土居信英
    • Organizer
      第44回日本分子生物学会年会(横浜)
    • Data Source
      KAKENHI-PROJECT-20H04535
  • [Presentation] Application of human syncytin1-derived fusogenic peptide to direct intracellular delivery of Cas9 protein-gRNA complex.2021

    • Author(s)
      Furuya, T., Fujiwara, K., Doi, N.
    • Organizer
      The 2021 International Chemical Congress of Pacific Basin Societies (オンライン開催)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H04535
  • [Presentation] Second extracellular loop of human CD9 is a cell-penetrating peptide.2021

    • Author(s)
      Kumeno, Y., Sudo, K., Fujiwara, K., Doi, N.
    • Organizer
      The 2021 International Chemical Congress of Pacific Basin Societies (オンライン開催)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H04535
  • [Presentation] Second extracellular loop of human CD9 is a cell-penetrating peptide2021

    • Author(s)
      Kumeno, Y., Sudo, K., Fujiwara, K., Doi, N.
    • Organizer
      The 2021 International Chemical Congress of Pacific Basin Societies
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H04823
  • [Presentation] Application of human syncytin1-derived fusogenic peptide to direct intracellular delivery of Cas9 protein-gRNA complex2021

    • Author(s)
      Furuya, T., Fujiwara, K., Doi, N.
    • Organizer
      The 2021 International Chemical Congress of Pacific Basin Societies
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H04823
  • [Presentation] CAPZA1過剰発現細胞を標的とした強制的オートファジー誘導タンパク質の開発2020

    • Author(s)
      坂田陸郎,津川仁,鈴木秀和,藤原慶,土居信英
    • Organizer
      第43回日本分子生物学会年会(オンライン開催)
    • Data Source
      KAKENHI-PROJECT-20H04535
  • [Presentation] 膜透過性ペプチドを用いたCas9タンパク質-gRNA複合体の直接的な細胞内送達2020

    • Author(s)
      古屋智規,藤原慶,土居信英
    • Organizer
      第43回日本分子生物学会年会(オンライン開催)
    • Data Source
      KAKENHI-PROJECT-20H04535
  • [Presentation] 細胞選択的なタンパク質デリバリーのためのヒト・シンシチン1由来膜透過促進ペプチドの最適化2020

    • Author(s)
      前村帆南,藤原慶,土居信英
    • Organizer
      第43回日本分子生物学会年会(オンライン開催)
    • Data Source
      KAKENHI-PROJECT-20H04535
  • [Presentation] LDL受容体を標的とする細胞選択的なタンパク質のデリバリーのためのヒト由来膜透過促進ペプチドの最適化2019

    • Author(s)
      前村帆南,岩城洸汰,藤原慶,土居信英
    • Organizer
      第35回日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H02103
  • [Presentation] ヒト・シンシチン1由来膜透過促進ペプチドのアラニンスキャニング変異解析2019

    • Author(s)
      鈴木麻友子,岩城洸汰,須藤慧,藤原慶,土居信英
    • Organizer
      第35回日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H02103
  • [Presentation] ヒト由来膜透過促進ペプチドS19を利用したsiRNAデリバリー2019

    • Author(s)
      中村桃子,藤原慶,土居信英
    • Organizer
      第35回日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H02103
  • [Presentation] ヒト由来膜透過促進ペプチドを利用したDDSの可能性2019

    • Author(s)
      土居信英
    • Organizer
      第21回ヒューマンサイエンス総合研究ワークショップ
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H02103
  • [Presentation] ペプチド医薬の細胞質送達に向けたヒト由来膜透過促進ペプチドの応用2019

    • Author(s)
      菊地萌希,岩城洸汰,藤原慶,土居信英
    • Organizer
      第35回日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H02103
  • [Presentation] Application of a human-derived fusogenic peptide to intracellular delivery of therapeutic peptides.2019

    • Author(s)
      Kikuchi, M., Iwaki, K., Fujiwara, K., Doi, N.
    • Organizer
      The Cold Spring Harbor Asia conference on Chemical Biology and Drug Discovery
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H02103
  • [Presentation] STALL-seq: selection of translational arrest sequences from a large E. coli genome-fragment library2018

    • Author(s)
      Hamano, T., Nagumo, Y., Chadani, Y., Tokunaga, M., Fujiwara, K., Taguchi, H., Doi, N.
    • Organizer
      International Symposium on "Proteins; from the Cradle to the Grave"
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05674
  • [Presentation] In vitro selection of eukaryotic translational arrest sequences from a random-sequence library using mRNA display2018

    • Author(s)
      Umehara, T., Hamano, T., Chadani, Y., Fujiwara, K., Taguchi, H., Doi, N.
    • Organizer
      International Symposium on "Proteins; from the Cradle to the Grave"
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05674
  • [Presentation] ヒト由来膜融合ペプチドと積み荷タンパク質の連結様式がその細胞質送達活性に与える影響2018

    • Author(s)
      岩城洸汰,菊地萌希,須藤慧,藤原慶,土居信英
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17H02103
  • [Presentation] タンパク質の細胞質送達を促進するヒト由来ペプチドの発見とDDSへの応用2018

    • Author(s)
      土居信英
    • Organizer
      LIP横浜オープンイノベーションカンファレンスIII
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H02103
  • [Presentation] 真核生物由来の翻訳停止配列を試験管内で大規模に探索する手法の開発2018

    • Author(s)
      梅原智文,濱野理,茶谷悠平,藤原慶,田口英樹,土居信英
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PUBLICLY-17H05674
  • [Presentation] STALL-seq法による大腸菌新規翻訳アレスト遺伝子の大規模探索と機能解析2018

    • Author(s)
      濱野理,南雲優,茶谷悠平,徳永真由子,藤原慶,田口英樹,土居信英
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PUBLICLY-17H05674
  • [Presentation] ヒト由来膜透過促進ペプチドによるバイオ医薬の効率的な細胞質送達の可能性評価2018

    • Author(s)
      菊地萌希,岩城洸汰,漆島穣一,須藤慧,藤原慶,土居信英
    • Organizer
      第34回日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H02103
  • [Presentation] ヒトSyncytin1由来膜融合ペプチドによるタンパク質の細胞質送達機構の解析2017

    • Author(s)
      岩城洸汰,須藤慧,光山隼史,藤原慶,土居信英
    • Organizer
      第33回日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H02103
  • [Presentation] mRNAディスプレイ法によるヒト抗GPCR単一ドメイン抗体の試験管内選択2017

    • Author(s)
      漆島穣一,海野佑樹,須藤慧,藤原慶,土居信英
    • Organizer
      第33回日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H02103
  • [Presentation] Large-scale identification of E. coli translational arrest sequences using mRNA display.2017

    • Author(s)
      Hamano, T., Nagumo, Y., Chadani, Y., Tokunaga, M., Fujiwara, K., Taguchi, H., Doi, N.
    • Organizer
      International Symposium on Protein Quality Control
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05674
  • [Presentation] In vitro selection of translational arrest sequences using mRNA display.2016

    • Author(s)
      Hamano, T., Nagumo, Y., Chadani, Y., Tokunaga, M., Fujiwara, K., Taguchi, H., Chiba, S., Ito, K., Doi, N.
    • Organizer
      Nascent Chain Biology Meeting
    • Place of Presentation
      Fuji Lake Hotel (Yamanashi, Japan)
    • Year and Date
      2016-09-01
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01543
  • [Presentation] ヒト由来膜融合促進ペプチドとpH依存性抗体を組み合わせた膜透過抗体の開発2016

    • Author(s)
      須藤慧,新倉啓介,藤原慶,土居信英
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-15K12545
  • [Presentation] PURE mRNAディスプレイ法による低分子抗体の試験管内選択2015

    • Author(s)
      海野佑樹,南雲優,藤原慶,堀澤健一,柳川弘志,角田慎一,向洋平,堤康央,土居信英
    • Organizer
      第38回日本分子生物学会年会・第88回日本生化学会大会合同大会
    • Place of Presentation
      神戸ポートアイランド(兵庫県・神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-25289298
  • [Presentation] ヒト由来膜融合促進ペプチドによる生体高分子の細胞内送達2015

    • Author(s)
      須藤慧,新倉啓介,藤原慶,土居信英
    • Organizer
      第31回日本DDS学会学術集会
    • Place of Presentation
      京王プラザホテル(東京都・新宿区)
    • Year and Date
      2015-07-02
    • Data Source
      KAKENHI-PROJECT-25289298
  • [Presentation] ヒト由来膜融合促進ペプチドによる生体高分子の細胞内送達2015

    • Author(s)
      須藤慧,新倉啓介,藤原慶,土居信英
    • Organizer
      第31回日本DDS学会学術集会
    • Place of Presentation
      京王プラザホテル(東京都・新宿区)
    • Year and Date
      2015-07-02
    • Data Source
      KAKENHI-PROJECT-15K12545
  • [Presentation] PURE mRNAディスプレイ法による低分子抗体の試験管内選択2015

    • Author(s)
      海野佑樹,南雲優,藤原慶,堀澤健一,柳川弘志,角田慎一,向洋平,堤康央,土居信英
    • Organizer
      第38回日本分子生物学会年会・第88回日本生化学会大会合同大会
    • Place of Presentation
      神戸ポートアイランド(兵庫県・神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PUBLICLY-15H01543
  • [Presentation] 共有結合型DNAディスプレイ法による二重特異性抗体の試験管内進化2015

    • Author(s)
      中山真尚,小宮尚子,藤原慶,堀澤健一,土居信英
    • Organizer
      第38回日本分子生物学会年会・第88回日本生化学会大会合同大会
    • Place of Presentation
      神戸ポートアイランド(兵庫県・神戸市)
    • Year and Date
      2015-12-03
    • Data Source
      KAKENHI-PROJECT-25289298
  • [Presentation] Bindin由来膜融合促進ペプチドを用いた膜透過抗体および膜透過促進抗体の構築2014

    • Author(s)
      新倉啓介,堀澤健一,土居信英
    • Organizer
      第30回日本DDS学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2014-07-30
    • Data Source
      KAKENHI-PROJECT-25289298
  • [Presentation] PURE mRNAディスプレイ法を用いた翻訳停止ペプチド配列の試験管内選択2014

    • Author(s)
      南雲優,水原真実子,藤原慶,堀澤健一,柳川弘志,土居信英
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-27
    • Data Source
      KAKENHI-PROJECT-25289298
  • [Presentation] 膜融合促進ペプチドB18およびB55による生体高分子の細胞内送達2014

    • Author(s)
      新倉啓介,藤原慶,堀澤健一,土居信英
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-26
    • Data Source
      KAKENHI-PROJECT-25289298
  • [Presentation] 共有結合型バイシストロン性DNAディスプレイ法による抗体Fab断片の試験管内進化2014

    • Author(s)
      小宮尚子,住田壮,藤原慶,堀澤健一,柳川弘志,土居信英
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-25
    • Data Source
      KAKENHI-PROJECT-25289298
  • [Presentation] ぺプチドおよび酵素の大腸菌表層ディスプレイに関する比較研究2013

    • Author(s)
      高谷祐介,堀津健一,土居信英
    • Organizer
      .第36回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Year and Date
      2013-12-04
    • Data Source
      KAKENHI-PROJECT-24656508
  • [Presentation] A novel chemical tool for proteomic analysis of translational control2013

    • Author(s)
      Horisawa K., Miyazawa T., Ohkawa K., Oka K. and Doi N.
    • Organizer
      The 12th Human Proteome Organisation World Congress
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Data Source
      KAKENHI-PROJECT-24500447
  • [Presentation] 酸化還元酵素のハイスループットなスクリーニング系の構築2013

    • Author(s)
      及木遼,片山道信,加藤太亮,杉谷藍,渡辺剛志,栄長泰明,松本佳宣,堀津健一,土居信英
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Year and Date
      2013-12-05
    • Data Source
      KAKENHI-PROJECT-24656508
  • [Presentation] 神経発生におけるRNA結合タンパク質Msi1による翻訳制御2012

    • Author(s)
      原裕恵、堀澤健一、松尾薫、柳川弘志、土居信英
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-24500447
  • [Presentation] In vitro virus (IVV)法を用いた人工癌幹細胞の接着を阻害する一本鎖抗体の選択2012

    • Author(s)
      田畠典子, 佐久間裕子, 清水孝恒, 佐谷秀行, 土居信英, 柳川弘志
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-22360351
  • [Presentation] RNA-binding protein Msi1 regulates the expression of an axon guidance receptor through translational repression2012

    • Author(s)
      Hara H., Horisawa K., Yanagawa H., Doi N.
    • Organizer
      Translational Control
    • Place of Presentation
      NewYork
    • Data Source
      KAKENHI-PROJECT-24500447
  • [Presentation] CD44とxCTの相互作用を阻害する抗CD44v一本鎖抗体の試験管内選択2011

    • Author(s)
      梅澤洋貴,田畠典子,佐久間裕子,竹中悠馬,松本佳宣,土居信英,永 野 修 ,佐 谷 秀 行 ,柳川弘志
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22360351
  • [Presentation] Translationally-regulated proteomics using biotinylated puromycin2011

    • Author(s)
      大川皓司, 堀澤健一, 柳川弘志, 土居信英
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-13
    • Data Source
      KAKENHI-PROJECT-22658111
  • [Presentation] 高親和性抗CCR5一本鎖抗体の中立的浮動による試験管内進化2011

    • Author(s)
      佐藤亮太,土居信英,三隅将吾,庄司省三,松島綱治,横地祥司,柳川弘志
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22360351
  • [Presentation] オンチップ共発現マイクロアレイによる転写制御ネットワーク解析2010

    • Author(s)
      早坂俊二, 井上鈴代, 堀澤健一, 柳川弘志, 土居信英
    • Organizer
      第33回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-08
    • Data Source
      KAKENHI-PROJECT-22658111
  • [Presentation] HIV の侵入を阻害する抗 CCR5 一本鎖抗体の試験管内進化2010

    • Author(s)
      佐藤亮太,土居信英,三隅将吾,松島綱治,横地祥司,柳川弘志
    • Organizer
      第33回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-22360351
  • [Presentation] In vitro display methods for heterodimeric proteins using in vitro compartmentaliza-tion2010

    • Author(s)
      Sumida, T., Yanagawa, H., Doi, N
    • Organizer
      Pacifichem 2010
    • Place of Presentation
      Honolulu
    • Data Source
      KAKENHI-PROJECT-22360351
  • [Presentation] In vitro selection of functional SH3 domains with reduced amino-acid alphabets2010

    • Author(s)
      Tanaka, J., Yanagawa, H., Doi, N.
    • Organizer
      Pacifichem 2010
    • Place of Presentation
      Honolulu
    • Data Source
      KAKENHI-PROJECT-22360351
  • [Presentation] DNAディスプレイ法によるFab抗体の完全試験管内選択2008

    • Author(s)
      住田壮, 土居信英, 柳川弘志
    • Organizer
      第81回日本生化学会・第31回日本分子生物学会合同年会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PROJECT-19360377
  • [Presentation] ビーズエマルジョンPCRとSTABLE法の組み合わせによる受容体ペプチドリガンド探索手法の開発2008

    • Author(s)
      丸岡優子, 住田壮, 山川奈津子, 土居信英, 柳川弘志
    • Organizer
      第81回日本生化学会・第31回日本分子生物学会合同年会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-12
    • Data Source
      KAKENHI-PROJECT-19360377
  • [Presentation] IVV法による選択実験の多用途性2008

    • Author(s)
      田畠典子, 佐久間裕子, 山川奈津子, 土居信英, 柳川弘志
    • Organizer
      第81回日本生化学会・第31回日本分子生物学会合同年会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PROJECT-19360377
  • [Presentation] 抗体医薬開発に向けたヒト一本鎖抗体のIVVスクリーニング2008

    • Author(s)
      木村香緒梨, 小磯崇, 田畠典子, 土居信英, 柳川弘志
    • Organizer
      第81回日本生化学会・第31回日本分子生物学会合同年会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PROJECT-19360377
  • [Presentation] In vitro virus法を用いたヒト一本鎖抗体の試験管内選択2007

    • Author(s)
      小磯崇, 福田伊佐央, 鬼丸美智子, 田畠典子, 土居信英, 高嶋秀昭, 柳川弘志
    • Organizer
      第80回日本生化学会・第30回日本分子生物学会合同年会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-11
    • Data Source
      KAKENHI-PROJECT-19360377
  • 1.  YANAGAWA Hiroshi (40327672)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 29 results
  • 2.  津川 仁 (30468483)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  MATSUSHIMA Koji (50222427)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 4.  HORISAWA Kenichi (70424207)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 8 results
  • 5.  SUZUKI HIDEKAZU (70255454)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  藤原 慶 (20580989)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 26 results
  • 7.  岡田 光 (50788916)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 8.  MISUMI Shogo (40264311)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 9.  EINAGA Yasuaki (00322066)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 10.  MATSUMOTO Yoshinori (60252318)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  WASHIO Takanori (50338266)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  MORI Hirotada (90182203)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  今井 貴雄 (10383712)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  芝田 晋介 (70407089)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  岡野 栄之 (60160694)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  佐藤 智典 (00162454)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  本多 政夫 (00272980)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 18.  堀本 勝久 (40238803)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  OYOBIKI Ryo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 20.  SHITARA Shunya
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  SHIMOKIHARA Shota
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  NIIKURA Keisuke
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 23.  SUDO Kei
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 24.  IWAKI Kouta
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 25.  SAYA Hideyuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  NAGATA Takashi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  高橋 栄夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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