OBINATA HIDERU 大日方英

… Alternative Names

Obinata Hideru 大日方英

OBINATA Hideru 大日方英

大日方英オビナタヒデル

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Researcher Number	50332557
Other IDs
Affiliation (Current)	2025: 群馬大学, 大学院医学系研究科, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 群馬大学, 大学院医学系研究科, 准教授 2016 – 2018: 群馬大学, 未来先端研究機構, 准教授 2008: Gunma University, 大学院医学系研究科, 助教 2007 – 2008: Gunma University, Graduate School of medicine, Assistant Professor 2006: 群馬大学, 大学院医学系研究科, 助手 … More 2005: 群馬大学, 大学院・医学系研究科, 助手 2004: 群馬大学, 医学系研究科, 助手 2001: 群馬大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator General medical chemistry / Basic Section 48040:Medical biochemistry-related Except Principal Investigator Basic Section 38050:Food sciences-related / Basic Section 52010:General internal medicine-related / Basic Section 59040:Nutrition science and health science-related / Basic Section 58040:Forensics medicine-related / Basic Section 55020:Digestive surgery-related / Basic Section 49010:Pathological biochemistry-related / Cardiovascular medicine / General medical chemistry / Biological Sciences
Keywords	Principal Investigator 受容体 / 生理活性脂質 / 近接ラベル化法 / 炎症 / S1P / 慢性炎症 / スフィンゴ脂質 / Gタンパク質共役型受容体 / 血管内皮細胞 / 脂質メディエーター … More / アポリポプロテイン / スフィンゴシン / HDL / アポリポタンパク / タンパク質精製 / スフィンゴシン１リン酸 / 質量分析 / アポリポタンパク質 / スフィンゴシン1リン酸 / 生理活性資質 / 脂質輸送 / リポタンパク質 / 酸化 / オーファン / 脂質 / 酸化ストレス / GPCR / オーファン受容体 … More Except Principal Investigator KDM2A / 脂肪酸 / 脂肪酸代謝 / 生理活性脂質 / トリグリセライド / リポ蛋白リパーゼ / GPIHBP1 / 毛細血管内皮細胞 / 脂質異常症 / 三次元セルモデル / エクソソーム / ヒト指紋筋細胞 / ヒト血管平滑筋細胞 / 虚血性心疾患 / エピジェネティクス / グリセロール３リン酸シャトル / リンゴ酸-アスパラギン酸シャトル / NADHシャトル / 代謝異常 / 脂肪肝 / 突然死 / 高度脂肪肝 / リピドーム / エクソーム / 多階層オミクス解析 / 抗がん剤感受性 / O-GlcNAc / KRAS / 新規治療標的 / O-GlcNAc修飾 / 膵がん / 酸化ストレス / メタボローム / DNA損傷応答 / エネルギー代謝 / アミノ酸代謝 / 活性酸素 / テロメア / 分岐鎖アミノ酸 / 細胞老化 / 糖新生 / Gallic acid / 糖代謝 / リボソームRNA / 没食子酸 / グルコース / 心不全 / グルコース代謝 / 代謝リモデリング / 構造リモデリング / 心肥大 / Keratinocyte / Stress response / DNA damage / Oxidized linoleic acid / Oxidized free fatty acid / G-protein coupled receptor / Bioactive lipid / Gタンパク質共役型受容体 / 皮膚角化細胞 / ストレス応答 / DNA損傷 / リノール酸酸化物 / 酸化遊離脂肪酸 / Gタンパク質生役型受容体 / MAPキナーゼ / cPLA2 / ホスホリパーゼ / 妊娠分娩障害 / 5-リポキシゲナーゼ / 炎症性疾患 / 血小板活性化因子 / ロイコトリエン / ホスホリパーゼA2 Less

NADHシャトル切り替え機構の解析とそれを制御する栄養成分の同定
- Principal Investigator
  
  田中祐司
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Takasaki University of Health and Welfare
疾患エクソソームを標的とした虚血性心疾患予防のための食品機能成分の探索と先制医療
- Principal Investigator
  
  中村彰男
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Jissen Women's University
Exome and lipidome analysis to elucidate the mechanisms of sudden death with hepatic steatosis
- Principal Investigator
  
  高橋遥一郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58040:Forensics medicine-related
- Research Institution
  University of Tsukuba
Study on the role of GPIHBP1, a GPI-anchored protein of capillary endothelial cells, in the pathophysiology of dyslipidemia
- Principal Investigator
  
  村上正巳
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Gunma University
Regulation of chronic inflammation of blood vessels by a bioactive lipid mediatorPrincipal Investigator
- Principal Investigator
  
  Obinata Hideru
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Gunma University
Elucidation of a novel cellular senescence mechanism modulated by branched-chain amino acid metabolism.
- Principal Investigator
  
  Konishi Akimitsu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Gunma University
膵がん治療におけるO-GlcNAc分解酵素OGAの重要性とその分子機構の解明
- Principal Investigator
  
  川端麗香
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Gunma University
Study of gallic acid about the function as an epigenetic controller for glyconeogenesis.
- Principal Investigator
  
  田中祐司
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Takasaki University of Health and Welfare
Pathophysiological significance of mechanisms underlying metabolic remodeling of hypertrophied heart
- Principal Investigator
  
  Iso Tatsuya
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Gunma University
A novel carrier protein for sphingosine 1-phosphatePrincipal Investigator
- Principal Investigator
  
  Obinata Hideru
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Gunma University
Search for novel lipid mediators and their receptors using oxidized lipid librariesPrincipal Investigator
- Principal Investigator
  
  OBINATA Hideru
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Gunma University
Functional analysis and its application of a G-protein coupled receptor, whose ligands are oxidized free fatty acids
- Principal Investigator
  
  IZUMI Takashi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Gunma University
脳に特異的に発現するオーファン受容体の新規脂溶性リガンドの同定Principal Investigator
- Principal Investigator
  
  大日方英
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Gunma University
ノックアウトマウスを使ったcPLA2の機能解析と新規PLA2の検索
- Principal Investigator
  
  IZUMI Takashi, 粂和彦
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (B)
- Review Section
  
  Biological Sciences
- Research Institution
  Gunma University
  The University of Tokyo

All 2024 2023 2022 2021 2020 2019 2018 2017 2008 2007 2006 2005 Other

All Journal Article Presentation Book Patent

[Book] 脂質クオリティ（有田誠編集）2018
- Author(s)
  大日方英（共著）
- Total Pages
  220
- Publisher
  羊土社
- ISBN
  9784758103718
- Data Source
  KAKENHI-PROJECT-16K08576
[Journal Article] 分岐鎖アミノ酸代謝の変調と老化・加齢性疾患2024
- Author(s)
  大日方英, 小西昭充
- Journal Title
  
  基礎老化研究
  
  Volume: 48(1) Pages: 3-8
- Data Source
  KAKENHI-PROJECT-21K06852
[Journal Article] Actin-binding protein filamin B regulates the cell-surface retention of endothelial sphingosine 1-phosphate receptor 12023
- Author(s)
  Zhao Xian、Kiyozuka Keisuke、Konishi Akimitsu、Kawabata-Iwakawa Reika、Minamishima Yoji Andrew、Obinata Hideru
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 299 Issue: 7 Pages: 104851-104851
- DOI
  10.1016/j.jbc.2023.104851
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06832
[Journal Article] Apolipoprotein M supports S1P production and conservation and mediates prolonged Akt activation via S1PR1 and S1PR32023
- Author(s)
  Kiyozuka Keisuke、Zhao Xian、Konishi Akimitsu、Minamishima Yoji Andrew、Obinata Hideru
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 174 Issue: 3 Pages: 253-266
- DOI
  10.1093/jb/mvad037
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06832
[Journal Article] Production of ROS by Gallic Acid Activates KDM2A to Reduce rRNA Transcription2020
- Author(s)
  Tanaka Yuji、Obinata Hideru、Konishi Akimitsu、Yamagiwa Noriyuki、Tsuneoka Makoto
- Journal Title
  
  Cells
  
  Volume: 9 Issue: 10 Pages: 2266-2266
- DOI
  10.3390/cells9102266
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K05942, KAKENHI-PROJECT-17K07798
[Journal Article] Sphingosine 1-phosphate and inflammation2019
- Author(s)
  Hideru Obinata and Timothy Hla
- Journal Title
  
  International Immunology
  
  Volume: 印刷中 Issue: 9 Pages: 617-625
- DOI
  10.1093/intimm/dxz037
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08576
[Journal Article] Glucose is preferentially utilized for biomass synthesis in pressure-overloaded hearts: Evidence from fatty acid binding protein-4 and -5 knockout mice.2018
- Author(s)
  Umbarawan Y, Syamsunarno MRAA, Koitabashi N, Yamaguchi A, Hanaoka H, Hishiki T, Nagahata-Naito Y, Obinata H, Sano M, Sunaga H, Matsui H, Tsushima Y, Suematsu M, Kurabayashi M, Iso T
- Journal Title
  
  Cardiovasc Res.
  
  Volume: - Issue: 8 Pages: 1132-1144
- DOI
  10.1093/cvr/cvy063
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01937, KAKENHI-PROJECT-16K09572, KAKENHI-PROJECT-17K09568, KAKENHI-PROJECT-16H05294, KAKENHI-PROJECT-16K15456, KAKENHI-PROJECT-16K19442
[Journal Article] Myocardial fatty acid uptake through CD36 is indispensable for sufficient bioenergetic metabolism to prevent progression of pressure overload-induced heart failure2018
- Author(s)
  Umbarawan Y, Syamsunarno MRAA, Koitabashi N, Obinata H, Yamaguchi A, Hanaoka H, Hishiki T, Hayakawa N, Sano M, Sunaga H, Matsui H, Tsushima Y, Suematsu M, Kurabayashi M, Iso T
- Journal Title
  
  Sci Rep
  
  Volume: 8(1) Issue: 1 Pages: 12035-12035
- DOI
  10.1038/s41598-018-30616-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09568, KAKENHI-PROJECT-16H05294, KAKENHI-PROJECT-16K01937, KAKENHI-PROJECT-16K09572, KAKENHI-PROJECT-16K19442
[Journal Article] Robust suppression of cardiac energy catabolism with marked accumulation of energy substrates during lipopolysaccharide-induced cardiac dysfunction in mice.2017
- Author(s)
  Umbarawan Y, Syamsunarno MR, Obinata H, Yamaguchi A, Sunaga H, Matsui H, Hishiki T, Matsuura T, Koitabashi N, Obokata M, Hanaoka H, Haque A, Kunimoto F, Tsushima Y, Suematsu M, Kurabayashi M, Iso T
- Journal Title
  
  Metabolism, clinical and experimental.
  
  Volume: - Pages: 47-57
- DOI
  10.1016/j.metabol.2017.09.003
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01937, KAKENHI-PROJECT-16K09572, KAKENHI-PROJECT-17K09568, KAKENHI-PROJECT-16K19442, KAKENHI-PROJECT-16H05294
[Journal Article] プロトン感知性GPCR研究の展開2008
- Author(s)
  大日方英, ら
- Journal Title
  
  生化学 80
  
  Pages: 113-118
- NAID
  10021190948
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790204
[Journal Article] Morphine is an exogenous ligand for MrgX2, a G protein-coupled receptor for cortistatin2008
- Author(s)
  Natsuyo Akuzawa, Hideru Obinata, Takashi Izumi, and Shigeki Takeda
- Journal Title
  
  Journal of Cell and Animal Biology 2
  
  Pages: 4-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790204
[Journal Article] G2A plays proinflammatory roles in human keratinocytes under oxidative stress as a receptor for 9-hydroxyoctadecadienoic acid2008
- Author(s)
  Hattori, T., Obinata, H., Ogawa, A., Kishi, M., Tatei, K. Ishikawa, O. Izumi, T.
- Journal Title
  
  J Investigative Dermatology 128
  
  Pages: 1123-1133
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390082
[Journal Article] プロトン感知性GPCR 研究の展開2008
- Author(s)
  大日方英、和泉孝志
- Journal Title
  
  生化学 80巻
  
  Pages: 113-118
- NAID
  10021190948
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790204
[Journal Article] G2A plays proinflammatory roles in human keratinocytes under oxidative stress as a receptor for 9-hydroxyoctadecadienoic acid2008
- Author(s)
  Tomoyasu Hattori, Hideru Obinata, Ai Ogawa, Mikiko Kishi, Kazuaki Tatei, Osamu Ishikawa, and Takashi Izumi
- Journal Title
  
  Journal of Investigative Dermatology 128
  
  Pages: 1123-1133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790204
[Journal Article] Morphine is an exogenous ligand for MrgX2, a G protein-coupled receptor for cortistatin2008
- Author(s)
  Akuzawa, N., Obinata, H., Izumi, T., Takeda, S.
- Journal Title
  
  J Cell Animal Biol 2
  
  Pages: 4-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390082
[Journal Article] Identification of novel peptide agonists from a random peptide library for a 5-oxo-ETE receptor, a receptor for bioacitive lipids2008
- Author(s)
  Yoshinori Sasaki, Takashi Tujii, Hideru Obinata, Takashi Izumi, Keiichi Yamada, and Rhoichi Katakai
- Journal Title
  
  Journal of Peptide Science 14
  
  Pages: 1251-1258
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790204
[Journal Article] プロトン感知性GPCR研究の展開2007
- Author(s)
  大日方英
- Journal Title
  
  生化学 80
  
  Pages: 113-118
- NAID
  10021190948
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390082
[Journal Article] オーファン受容体のリガンド探索 -新たな生命現象の理解と創薬を目指して-2007
- Author(s)
  大日方英, 和泉孝志
- Journal Title
  
  呼吸 26・3
  
  Pages: 247-253
- Data Source
  KAKENHI-PROJECT-18390082
[Journal Article] 表皮角化細胞におけるGタンパク質共役型受容体G2Aの生理作用2007
- Author(s)
  大日方英
- Journal Title
  
  脂質生化学研究 49
  
  Pages: 38-40
- NAID
  10024355151
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390082
[Journal Article] オーファン受容体のリガンド探索-新たな生命現象の理解と創薬を目指して-2007
- Author(s)
  大日方英, 和泉孝志
- Journal Title
  
  呼吸 26・3
  
  Pages: 247-253
- Data Source
  KAKENHI-PROJECT-16790161
[Journal Article] 5-Oxo-eicosatetraenoic acid-induced chemotaxis : identification of a responsible receptor hGPCR48 and negative regulation by G protein G12/132006
- Author(s)
  Hideru Obinata et al.
- Journal Title
  
  Journal of Biochemistry 139・3
  
  Pages: 543-549
- Data Source
  KAKENHI-PROJECT-16790161
[Journal Article] Identification of 9-hydroxyoctadecadienoic acid and other oxidized free fatty acids as ligands of the G protein-coupled receptor G2A2005
- Author(s)
  大日方英
- Journal Title
  
  Journal of Biological Chemistry 280・49
  
  Pages: 40676-40683
- Data Source
  KAKENHI-PROJECT-16790161
[Journal Article] G2A as a receptor for oxidized free fatty acids
- Author(s)
  Hideru Obinata, et.al.
- Journal Title
  
  Prostaglandins and Other Lipid Mediators (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790204
[Journal Article] G2A as a receptor for oxidized free fatty acids
- Author(s)
  Hideru Obinata and Takashi Izumi
- Journal Title
  
  Prostaglandins and Other Lipid Mediators(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790204
[Patent] AGONIST TO G PROTEIN-COUPLED RECEPTOR G2A AND METHOD OF SCREENING G2A ACTIVITY CONTROLLER2006
- Inventor(s)
  和泉孝志, 大日方英
- Industrial Property Rights Holder
  国立大学法人群馬大学
- Filing Date
  2006-06-21
- Data Source
  KAKENHI-PROJECT-18390082
[Patent] AGONIST TO G PROTEIN-COUPLED RECEPTOR G2A AND METHOD OF SCREENING G2A ACTIVITY CONTROLLER2006
- Inventor(s)
  和泉孝志・大日方英
- Industrial Property Rights Holder
  国立大学法人群馬大学
- Filing Date
  2006-06-21
- Description
  「研究成果報告書概要(和文)」より
- Overseas
- Data Source
  KAKENHI-PROJECT-18390082
[Patent] Gタンパク質共役型受容体G2Aの作動薬、及びG2A活性調節薬のスクリーニング方法2005
- Inventor(s)
  和泉孝志, 大日方英
- Industrial Property Rights Holder
  国立大学法人群馬大学
- Filing Date
  2005-06-22
- Data Source
  KAKENHI-PROJECT-16790161
[Patent] Gタンパク質共役型受容体G2Aの作動薬、及びG2A活性調節薬のスクリーニングッ方法2005
- Inventor(s)
  和泉孝志, 大日方英
- Industrial Property Rights Holder
  群馬大学
- Industrial Property Number
  2005-182051
- Filing Date
  2005-06-22
- Data Source
  KAKENHI-PROJECT-16790161
[Presentation] Actin-binding protein Filamin B regulates endothelial sphingosine 1-phosphate receptor 1 functions by keeping the receptor on cell-surface2023
- Author(s)
  Hideru Obinata, Xian Zhao, Keisuke Kiyozuka, Akimitsu Konishi, Yoji Andrew Minamishima
- Organizer
  第96回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-21K06832
[Presentation] Cell-surface retention of endothelial sphingosine 1-phosphate receptor 1 modulates the signaling efficiency2023
- Author(s)
  Hideru Obinata
- Organizer
  FASEB Summer Research Conference The lysophospholipid and related mediators conference: from bench to clinic
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06832
[Presentation] スフィンゴシン1リン酸による血管機能の制御2023
- Author(s)
  大日方英
- Organizer
  第193回東京脂質談話会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06832
[Presentation] テロメア短縮系を用いた効率的な複製老化系の樹立および分岐鎖アミノ酸代謝の細胞老化における役割の解析2023
- Author(s)
  入江和樹, 荒牧佑磨, 土田愛子, 大日方英, 和泉孝志, 南嶋洋司, 小西昭充
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06852
[Presentation] 代謝物解析から迫る細胞・個体老化~分岐鎖アミノ酸代謝の変調を中心に~2023
- Author(s)
  大日方英, 荒牧佑磨, 土田愛子, 入江和樹, 南嶋洋司, 小西昭充
- Organizer
  第46回日本基礎老化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06852
[Presentation] 細胞老化過程における分岐鎖アミノ酸代謝の変調2023
- Author(s)
  大日方英, 荒牧佑磨, 入江和樹, 南嶋洋司, 小西昭充
- Organizer
  第71回質量分析総合討論会
- Data Source
  KAKENHI-PROJECT-21K06852
[Presentation] NADHシャトル阻害剤はKDM2Aを介したリボソームRNA転写抑制を誘導する2023
- Author(s)
  田中祐司,　大日方英,　常岡誠
- Organizer
  2023年度　日本生化学会関東支部例会
- Data Source
  KAKENHI-PROJECT-20K05942
[Presentation] Filamin B regulates the cell surface retention of endothelial sphingosine 1-phosphate receptor 12022
- Author(s)
  Xian Zhao, Keisuke Kiyozuka, Akimitsu Konishi, Yoji Andrew Minamishima, Hideru Obinata
- Organizer
  International conference on bioactive lipids in cancer inflammation and disease progession
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06832
[Presentation] Filamin B regulates the endocytosis of endothelial sphingosine 1-phosphate receptor 12022
- Author(s)
  Zhao Xian, Keisuke Kyozuka, Akimitsu Konishi, Yoji A. Minamishima, Hideru Obinata
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06852
[Presentation] O-GlcNAcase is essential for proliferation in KRAS wild-type pancreatic cancer cell.2022
- Author(s)
  Reika Kawabata, Xian Zhao, Navchaa Gombodorj, Takehiko Yokobori, Hideru Obinata
- Organizer
  第81回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08680
[Presentation] Filamin B regulates the endocytosis of endothelial sphingosine 1-phosphate receptor 12022
- Author(s)
  Xian Zhao, Keisuke Kiyozuka, Akimitsu Konishi, Yoji Andrew Minamishima, Hideru Obinata
- Organizer
  第95回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-21K06832
[Presentation] Utility of glycosylation regulation for pancreatic cancer treatment.2021
- Author(s)
  Reika Kawabata, Hideru Obinata, Navchaa Gombodorj, Takehiko Yokobori
- Organizer
  The 80th Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-21K08680
[Presentation] KDM2A依存的なヒストン脱メチル化を伴うrRNA転写抑制は没食子酸で誘導される。2021
- Author(s)
  田中祐司、大日方英、伊東千華、小西昭充、常岡誠
- Organizer
  第３８回　染色体ワークショップ、第１９回核ダイナミクス研究会ポスターno.30
- Data Source
  KAKENHI-PROJECT-20K05942
[Presentation] 分岐鎖アミノ酸代謝の変調による細胞老化制御機構2021
- Author(s)
  小西昭充、荒牧佑磨、大日方英、本田真也、和泉孝志、清水重臣、南嶋洋司
- Organizer
  日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K06852
[Presentation] 分岐鎖アミノ酸代謝の変調による細胞老化制御機構2021
- Author(s)
  荒牧佑磨、大日方英、本田真也、和泉孝志、清水重臣、南嶋洋司、小西昭充
- Organizer
  日本生化学会関東支部例会
- Data Source
  KAKENHI-PROJECT-21K06852
[Presentation] 没食子酸はKDM2A依存的なrRNA転写抑制を通じてMCF-7細胞の増殖を抑制する。2021
- Author(s)
  田中祐司、大日方英、小西昭充、常岡誠
- Organizer
  2021年度日本生化学会関東支部例会（誌上開催）
- Data Source
  KAKENHI-PROJECT-20K05942
[Presentation] Modulation of Cellular Senescence by Branched- Chain Amino Acid Metabolism2021
- Author(s)
  Yuma Aramaki, Hideru Obinata, Shinya Honda, Takashi Izumi, Shigeomi Shimizu, Yoji A. Minamishima, Akimitsu Konishi
- Organizer
  International Cell Senescence Association Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06852
[Presentation] KDM2A依存的なrRNA転写抑制はメトホルミン、及び没食子酸により誘導される。2020
- Author(s)
  田中祐司、大日方英、伊東千華、小西昭充、常岡誠
- Organizer
  第４３回日本分子生物学会年会　1P-0326
- Data Source
  KAKENHI-PROJECT-20K05942
[Presentation] Novel S1P chaperone activity in the plasma from ApoM/albumin-double knockout mice2018
- Author(s)
  Obinata H, Wada Y, Kuo A, Swendeman SL, Liu C, Izumi T, and Hla T.
- Organizer
  日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K08576
[Presentation] Exploration of novel sphingosine 1 phosphate carrier proteins2017
- Author(s)
  Wada Y, Obinata H, Swendeman SL, Liu CH, Nagumo R, Hla T, and Izumi T.
- Organizer
  Consortium of Biological Sciences 2017
- Data Source
  KAKENHI-PROJECT-16K08576
[Presentation] Gタンパク質共役型受容体G2A の新規スプライシングバリアントの同定と機能解析2008
- Author(s)
  小川愛、大日方英、服部友保、岸美紀子、陳可欣、立井一明、和泉孝志
- Organizer
  第50回脂質生化学会
- Place of Presentation
  徳島
- Year and Date
  2008-06-05
- Data Source
  KAKENHI-PROJECT-19790204
[Presentation] 9-hydroxyoctadecadienoic acid, one of the oxidized metabolites of linoleicacid, induces cell cycle arrest in the G1 phase in primary human keratinocytes2008
- Author(s)
  Hideru Obinata, et.al.
- Organizer
  The 3^<rd> international workshop on cell regulations in division and arrest under stress
- Place of Presentation
  沖縄
- Year and Date
  2008-04-06
- Data Source
  KAKENHI-PROJECT-19790204
[Presentation] 9-hydroxyoctadecadienoic acid, one of the oxidized metabolites of linoleic acid, induces cell cycle arrest in the G1 phase in primary human keratinocytes2008
- Author(s)
  Hideru Obinata and Takashi Izumi
- Organizer
  The 3rd international workshop on cell regulations in division and arrest under stress
- Place of Presentation
  沖縄
- Year and Date
  2008-04-06
- Data Source
  KAKENHI-PROJECT-19790204
[Presentation] 酸化遊離脂肪酸をリガンドとするG2Aの生理機能2008
- Author(s)
  和泉孝志、大日方英、服部友保、小川愛、岸美紀子、立井一明
- Organizer
  第50回脂質生化学会
- Place of Presentation
  徳島
- Year and Date
  2008-06-05
- Data Source
  KAKENHI-PROJECT-19790204
[Presentation] 9-hydroxyoctadecadienoic acid, one of the oxidized metabolites of linoleic acid, induces cell cycle arrest in the G1 phase in primary human keratinocytes2008
- Author(s)
  Hideru Obinata, Ai Ogawa, Tomoyasu Hattori, Mikiko Kishi, Kazuaki Tatei, and Takashi Izumi
- Organizer
  第31回日本分子生物学会年会、第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-19790204
[Presentation] 9-hydroxyoctadecadienoic acid, one of the oxidized metabolites of linoleicacid, induces cell cycle arrest in the G1 phase in primary human keratinocytes2008
- Author(s)
  Hideru Obinata, et.al.
- Organizer
  第31回日本分子生物学会年会、第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-19790204
[Presentation] Oxidized free fatty acid-G2A signaling mediates alarm signal May, 12, under oxidative stress2007
- Author(s)
  Izumi, T., Obinata, H., Hattori, T., Ogawa, A., Chen, K., Barliana, M. I. Kishi, M., Tatei, K.
- Organizer
  3rd International Conference on Phospholipases A2 and Lipid Mediators
- Place of Presentation
  Sorrento, Italy
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390082
[Presentation] G2A mediates signals of oxidized free fatty acids in human keratinocytes2007
- Author(s)
  Hideru Obinata, Tomoyasu Hattori, Ai Ogawa, Kazuaki Tatei, and Takashi Izumi
- Organizer
  3rd International conference on phospholipase A2 and lipid mediators
- Place of Presentation
  Italy
- Year and Date
  2007-05-09
- Data Source
  KAKENHI-PROJECT-19790204
[Presentation] G2A mediates signals of oxidized free fatty acids in human keratinocytes2007
- Author(s)
  Obinata, H.
- Organizer
  3rd International Conference on Phospholipases A2 and Lipid Mediators
- Place of Presentation
  Sorrento, Italy
- Year and Date
  2007-05-09
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390082
[Presentation] 生細胞におけるGPCR 活性の表面プラズモン共鳴(SPR)による観察2007
- Author(s)
  陳可欣、大日方英、和泉孝志
- Organizer
  第30回日本分子生物学会年会、第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19790204
[Presentation] Gタンパク質共役型受容体G2Aのスプライシングバリアントの同定と機能解析2007
- Author(s)
  小川愛、大日方英、服部友保、立井一明、和泉孝志
- Organizer
  第30回日本分子生物学会年会、第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19790204
[Presentation] 表皮角化細胞におけるGタンパク質共役型受容体G2Aの生理作用2007
- Author(s)
  大日方英、服部友保、小川愛、平野瞳子、陳可欣、Melisa Intan Barliana、岸美紀子、立井一明、和泉孝志
- Organizer
  第49回脂質生化学会
- Place of Presentation
  札幌
- Year and Date
  2007-06-05
- Data Source
  KAKENHI-PROJECT-19790204
[Presentation] Oxidized free fatty acid-G2A signaling mediates alarm signal under oxidative stresses2007
- Author(s)
  Takashi Izumi, Hideru Obinata, Tomoyasu Hattori, Ai Ogawa, Kexin Chen, Melisa Intan Barliana, Mikiko Kishi, and Kazuaki Tatei
- Organizer
  3rd International conference on phospholipase A2 and lipid mediators
- Place of Presentation
  Italy
- Year and Date
  2007-05-09
- Data Source
  KAKENHI-PROJECT-19790204
[Presentation] Human G2A is a G protein-coupled receptor activated by 9-hydroxyoctadecadienoic acid and other oxidized free fatty acids2006
- Author(s)
  Obinata, H., Hattori, T., Tatei, K., Izumi, T
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology
- Place of Presentation
  Kyoto
- Year and Date
  2006-06-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390082
[Presentation] Human G2A is a G protein-coupled receptor activated by 9-hydroxyoctadecadienoic acid and other oxidized free fatty acids2006
- Author(s)
  Obinata, H.
- Organizer
  20th IUBMB international congress of biochemistry and molecular biology
- Place of Presentation
  Kyoto
- Year and Date
  2006-06-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390082

1. IZUMI Takashi (70232361)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
2. 川端麗香 (90721928)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
3. 田中祐司 (90453422)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
4. TATEI Kazuaki (00192633)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. KISHI Mikiko (90396630)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. Iso Tatsuya (10400756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. Konishi Akimitsu (50381877)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
8. 粂和彦 (30251218)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 清水孝雄 (80127092)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 魚住尚紀 (70313096)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 南嶋洋司 (20593966)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
12. 小林良祐 (30802855)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 畑田出穂 (50212147)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 横堀武彦 (60420098)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. 調憲 (70264025)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 高橋遥一郎 (50640538)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 大嶋紀安 (30360514)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 平野瞳子 (20643810)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 窪理英子 (40747127)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 佐野利恵 (70455955)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 早川輝 (90758575)

# of Collaborated Projects: 1 results

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22. 中村彰男 (30282388)

# of Collaborated Projects: 1 results

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23. 岸博子 (40359899)

# of Collaborated Projects: 1 results

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24. 村上正巳 (30241871)

# of Collaborated Projects: 1 results

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25. 中嶋克行 (10444051)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 常川勝彦 (30436307)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 葭田明弘 (40794194)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 木村孝穂 (90396656)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. Hla Timothy

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
30. 菱木貴子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

OBINATA HIDERU 大日方 英

Obinata Hideru 大日方 英

OBINATA Hideru 大日方 英

大日方 英 オビナタ ヒデル

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Regulation of chronic inflammation of blood vessels by a bioactive lipid mediatorPrincipal Investigator

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A novel carrier protein for sphingosine 1-phosphatePrincipal Investigator

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Search for novel lipid mediators and their receptors using oxidized lipid librariesPrincipal Investigator

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脳に特異的に発現するオーファン受容体の新規脂溶性リガンドの同定Principal Investigator

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OBINATA HIDERU 大日方英

Obinata Hideru 大日方英

OBINATA Hideru 大日方英

大日方英オビナタヒデル