Nagai Shigenori 永井重徳

… Alternative Names

NAGAI Shigenori 永井重徳

永井重徳ナガイシゲノリ

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Researcher Number	50348801
Other IDs
Affiliation (Current)	2025: 静岡県立大学, 食品栄養科学部, 教授 2025: 東京科学大学, 大学院医歯学総合研究科, 准教授
Affiliation (based on the past Project Information) *help	2016 – 2024: 東京医科歯科大学, 大学院医歯学総合研究科, 准教授 2013 – 2016: 東京医科歯科大学, 医歯(薬)学総合研究科, 准教授 2014: 東京医科歯科大学大学院, 医歯学総合研究科, 准教授 2012: 慶應義塾大学, 医学部, 助教 2007 – 2010: Keio University, 医学部, 助教 2006: 慶應義塾大学, 医学部, 助手 2003 – 2004: 慶應義塾大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Immunology / Pathobiological dentistry/Dental radiology / Basic Section 49070:Immunology-related / Biological Sciences Except Principal Investigator Basic Section 56070:Plastic and reconstructive surgery-related / Immunology / Medium-sized Section 90:Biomedical engineering and related fields / Medium-sized Section 57:Oral science and related fields / Biomedical engineering/Biomaterial science and engineering / Pathobiological dentistry/Dental radiology / Biomedical engineering/Biological material science
Keywords	Principal Investigator PI3K / 免疫学 / ヘルパーT細胞 / Th17 / Helicobacter pylori / 感染免疫 / 免疫麻痺 / 粘膜免疫 / 細菌感染 / IL-10 … More / Akt / Th17分化 / p70S6K / mTORC / mTORC1 / ケモカイン / 腸管免疫 / Th17細胞 / 血小板 / B細胞 / 肥満細胞 / ヘリコバクターピロリ / 細胞 / IL-12 / c-Met / Internalin B / リステリア / 樹状細胞 … More Except Principal Investigator T細胞 / バイオセラミックス / 免疫細胞 / イムノセラミックス / 樹状細胞 / 頭蓋冠 / 骨修復 / 口腔癌 / 免疫チェックポイント分子 / 口腔粘膜 / 免疫制御 / アパタイト / バイオマテリアル / 養子免疫療法 / フローサイトメーター / ホウ素含有アパタイト / イノシトールリン酸 / 水酸アパタイト / 骨芽細胞 / 中胚葉 / 神経堤 / 抗腫瘍効果 / ポリロタキサン / 頭蓋冠骨 / メカノシグナル / マクロファージ / 頭蓋冠幹細胞 / ナノゲル / 骨欠損 / 骨髄間質細胞 / M2マクロファージ / BMP2 / FGF18 / 膜性骨 / マウス頭蓋冠 / 免疫抑制御 / 慢性炎症 / 制御細胞 / mTORC1 / ｍTORC1 / サイトカイン / mTOR / 生体材料 / ゾル-ゲル法 / 免疫療法 / 歯髄 / 免疫抑制 / 免疫寛容 / 歯学 / 免疫学 / 接触過敏症 / 粘膜上皮細胞 / フローサイトメトリー / NK細胞 / IFNγ / IL-17 / ノックアウトマウス / 胃炎 / パイエル板 Less

頭蓋顎顔面修復への応用を目指した、heterogeneticな組織/細胞の動態解明
- Principal Investigator
  
  井関祥子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Tokyo Medical and Dental University
Role of FoxO1 on Tr1 differentiationPrincipal Investigator
- Principal Investigator
  
  永井重徳
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Tokyo Medical and Dental University
Cellular dynamics in calvarial bone healing
- Principal Investigator
  
  ISEKI Sachiko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Tokyo Medical and Dental University
Clarification of Mechanism of Functional Expression of Bioceramics Acting on an Immune System
- Principal Investigator
  
  AIZAWA MAMORU
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Meiji University
Dynamics of immune regulation in oral chronic inflammation and cancer, and their connection to systemic immunity
- Principal Investigator
  
  Azuma Miyuki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Tokyo Medical and Dental University
Clarification of immunoregulatory mechanisms by crosstalk of immune cellsPrincipal Investigator
- Principal Investigator
  
  Nagai Shigenori
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Tokyo Medical and Dental University
Development of immunoceramics acting on immune system and their functions
- Principal Investigator
  
  Aizawa Mamoru
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Meiji University
Analysis of characteristic immune regulation in the oral cavity
- Principal Investigator
  
  Azuma Miyuki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Tokyo Medical and Dental University
Differentiation and function of Foxp3-negative IL-10-producing regulatory T cells on mucosal bacterial infectionPrincipal Investigator
- Principal Investigator
  
  Nagai Shigenori
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Tokyo Medical and Dental University
The role of mTORC1 in dendritic cells in adaptive immune response
- Principal Investigator
  
  OHTANI Masashi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Toho University
  Tokyo University of Science
Development of immunoceramics acting on immune system and their functions
- Principal Investigator
  
  AIZAWA Mamoru
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Meiji University
The role of PI3K-Akt-mTORC1 signaling pathway on Th17 differentiationPrincipal Investigator
- Principal Investigator
  
  NAGAI Shigenori
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Tokyo Medical and Dental University
  Keio University
Role of Helper T cells on Helicobacter pylori-induced gastritis.Principal Investigator
- Principal Investigator
  
  NAGAI Shigenori
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Keio University
腸管免疫系の炎症誘発に関わるTh17細胞の機能・分化におけるPI3Kの役割Principal Investigator
- Principal Investigator
  
  永井重徳
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
Immune regulation of B cells and platelets by mast cells on Helicobacter pylori infectionPrincipal Investigator
- Principal Investigator
  
  NAGAI Shigenori
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Keio University
ヘリコバクター感染における抗原捕捉機構の解明
- Principal Investigator
  
  小安重夫
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Immunology
- Research Institution
  Keio University
リステリア感染における樹状細胞の役割とその分子機構Principal Investigator
- Principal Investigator
  
  永井重徳
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Keio University

[Book] Co-signal Molecules in T cell Activation2019
- Author(s)
  Nagai S, Azuma M
- Total Pages
  326
- Publisher
  Springer
- ISBN
  9789813297166
- Data Source
  KAKENHI-PROJECT-17H04376
[Book] アバス－リックマン－ピレ「分子細胞免疫学」第7版（第12章）2014
- Author(s)
  白木文子，永井重徳．（監訳：松島綱治，山田幸宏）
- Total Pages
  627
- Publisher
  エルゼビア・ジャパン
- Data Source
  KAKENHI-PROJECT-26293400
[Journal Article] Augmented effect of fibroblast growth factor 18 in bone morphogenetic protein 2-induced calvarial bone healing by activation of CCL2/CCR2 axis on M2 macrophage polarization2023
- Author(s)
  Namangkalakul Worachat、Nagai Shigenori、Jin Chengxue、Nakahama Ken-ichi、Yoshimoto Yuki、Ueha Satoshi、Akiyoshi Kazunari、Matsushima Kouji、Nakashima Tomoki、Takechi Masaki、Iseki Sachiko
- Journal Title
  
  Journal of Tissue Engineering
  
  Volume: 14 Pages: 1-19
- DOI
  10.1177/20417314231187960
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19613, KAKENHI-PROJECT-23K06593, KAKENHI-PROJECT-21H03098
[Journal Article] Personal immune profiles: Diversity and prognostic value for oral tongue squamous cell carcinoma evaluated by comprehensive immune parameter analyses with multiplex immunofluorescence2023
- Author(s)
  Daroonpan Pissacha、Ouchi Ryo、Zhang Chenyang、Nagai Shigenori、Nishii Naoto、Kashima Yoshihisa、Tsushima Fumihiko、Harada Hiroyuki、Hamagaki Miwako、Ikeda Tohru、Aida Jun、Kaomongkolgit Ruchadaporn、Azuma Miyuki
- Journal Title
  
  Oral Oncology
  
  Volume: 143 Pages: 106458-106458
- DOI
  10.1016/j.oraloncology.2023.106458
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06593, KAKENHI-PROJECT-21H03138
[Journal Article] Polymorphonuclear myeloid-derived cells that contribute to the immune paralysis are generated in the early phase of sepsis vis the PD-1/PD-L1 pathway2021
- Author(s)
  Ao Xiang、Yang Yue、Okiji Takashi、Azuma Miyuki、Nagai Shigenori
- Journal Title
  
  Infection and Immunity, Online ahead of print.
  
  Volume: - Issue: 6
- DOI
  10.1128/iai.00771-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H04066
[Journal Article] 6.Hypoxia-inducible factor 1α promotes interleukin 1β and tumour necrosis factor α expression in lipopolysaccharide-stimulated human dental pulp cells2020
- Author(s)
  Fujii M, Kawashima N, Tazawa K, Hashimoto K, Nara K, Noda S, Nagai S, Okiji T
- Journal Title
  
  International Endodontic Journal.
  
  Volume: 53 Issue: 5 Pages: 636-646
- DOI
  10.1111/iej.13264
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K17039, KAKENHI-PROJECT-19K24137, KAKENHI-PROJECT-17H04376, KAKENHI-PROJECT-17H04380
[Journal Article] Tolerogenic properties of CD206+ macrophages appeared in the sublingual mucosa after repeated antigen-painting.2020
- Author(s)
  Yang Y, Nagai S, Kang S, Xia Y, Kawano Y, Miyake K, Karasuyama H, Azuma M.
- Journal Title
  
  International Immunology
  
  Volume: - Issue: 8 Pages: 509-518
- DOI
  10.1093/intimm/dxaa014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04066, KAKENHI-PROJECT-17H04376, KAKENHI-PROJECT-18K15180, KAKENHI-PROJECT-19H01025
[Journal Article] Fabrications of boron-containing apatite ceramics via ultrasonic spray-pyrolysis route and their responses to immunocytes.2020
- Author(s)
  Nakagawa D, Nakamura M, Nagai S, *Aizawa M.
- Journal Title
  
  J Mater Sci Mater Med.
  
  Volume: 31 Issue: 2 Pages: 20-20
- DOI
  10.1007/s10856-020-6358-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04376
[Journal Article] Orthotopic tongue squamous cell carcinoma (SCC) model exhibiting a different tumor-infiltrating T-cell status with margin-restricted CD8+ T cells and regulatory T cell-dominance, compared to skin SCC.2020
- Author(s)
  Kashima Y, Nishii N, Tachinami H, Furusawa E, Nagai S, Harada H, Azuma M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 20 Issue: 1 Pages: 218-224
- DOI
  10.1016/j.bbrc.2020.03.022
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K24088, KAKENHI-PROJECT-19K24138, KAKENHI-PROJECT-18H04066, KAKENHI-PROJECT-17H04376
[Journal Article] 5.HIF1α inhibits LPS-mediated induction of IL-6 synthesis via SOCS3-dependent CEBPβ suppression in human dental pulp cells2020
- Author(s)
  Mayuko Fujii; Kento Tazawa; Kentaro Hashimoto; Keisuke Nara; Sonoko Noda; Masashi Kuramoto; Shion Orikasa; Shigenori Nagai; Takashi Okiji
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 522 Issue: 2 Pages: 308-314
- DOI
  10.1016/j.bbrc.2019.11.032
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K17039, KAKENHI-PROJECT-17H04376, KAKENHI-PROJECT-17H04380, KAKENHI-PROJECT-19K24137
[Journal Article] Responses of Immune Cells to Hydroxyapatite Ceramics Loaded with Immunostimulators.2019
- Author(s)
  Kagami S, Kizukuri R, Nagai S, *Aizawa M.
- Journal Title
  
  J Soc Inorg Mater Jpn.
  
  Volume: 26 Pages: 74-81
- NAID
  40021829116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04376
[Journal Article] Silencing of PD-L2/B7-DC by Topical Application of Small Interfering RNA Inhibits Elicitation of Contact Hypersensitivity2019
- Author(s)
  Furusawa Emi、Ohno Tatsukuni、Nagai Shigenori、Noda Taisei、Komiyama Takuya、Kobayashi Katsunori、Hamomato Hidetoshi、Miyashin Michiyo、Yokozeki Hiroo、Azuma Miyuki
- Journal Title
  
  Journal of Investigative Dermatology
  
  Volume: - Issue: 10 Pages: 2164-2173
- DOI
  10.1016/j.jid.2019.02.037
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04066, KAKENHI-PROJECT-19K24138, KAKENHI-PROJECT-17H04376
[Journal Article] Endogenous IL-33 exerts CD8+ T cell antitumor responses overcoming pro-tumor effects by regulatory T cells in a colon carcinoma model.2019
- Author(s)
  Xia Y, Ohno T, Nishii N, Bhingare A, Tachinami H, Kashima Y, Nagai S, Saito H, Nakae S, Azuma M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 2019 Issue: 2 Pages: 331-336
- DOI
  10.1016/j.bbrc.2019.08.058
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K24088, KAKENHI-PROJECT-18H04066, KAKENHI-PROJECT-17H04376, KAKENHI-PROJECT-18H02847, KAKENHI-PROJECT-17K11663
[Journal Article] Differences of tumor-recruiting myeloid cells in murine squamous cell carcinoma influence the efficacy of immunotherapy combined with a TLR7 agonist and PD-L1 blockade2019
- Author(s)
  Tachinami Hidetake、Nishii Naoto、Xia Yulong、Kashima Yoshihisa、Ohno Tatsukuni、Nagai Shigenori、Li Lixin、Lau Walter、Tomihara Kei、Noguchi Makoto、Azuma Miyuki
- Journal Title
  
  Oral Oncology
  
  Volume: 91 Pages: 21-28
- DOI
  10.1016/j.oraloncology.2019.02.014
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04066, KAKENHI-PROJECT-17H04376, KAKENHI-PROJECT-19K24088
[Journal Article] Systemic administration of a TLR7 agonist attenuates regulatory T cells by dendritic cell modification and overcomes resistance to PD-L1 blockade therapy.2018
- Author(s)
  Nishii N, Tachinami H, Kondo Y, Xia Y, Kashima Y, Ohno T, Nagai S, Li L, Lau W, Harada H, Azuma M.
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 17 Pages: 13301-13312
- DOI
  10.18632/oncotarget.24327
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04376, KAKENHI-PROJECT-19K24088
[Journal Article] PI3K-Akt pathway enhances the differentiation of interleukin-27-induced type 1 regulatory T cells.2017
- Author(s)
  Nadya NA, Tezuka H, Ohteki T, Matsuda S., Azuma M, and *Nagai S.
- Journal Title
  
  Immunology
  
  Volume: 152 Issue: 3 Pages: 507-516
- DOI
  10.1111/imm.12789
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19937, KAKENHI-PROJECT-17H04376
[Journal Article] Morphological and functional changes in RAW264 macrophage-like cells in response to a hydrated layer of carbonate-substituted hydroxyapatite2017
- Author(s)
  Igeta K, Kuwamura Y, Horiuchi N, Nozaki K, Shiraishi D, Aizawa M, Hashimoto K, Yamashita K, Nagai A
- Journal Title
  
  J. Biomed. Mater. Res. A
  
  Volume: 105 Issue: 4 Pages: 1063-1070
- DOI
  10.1002/jbm.a.35997
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K01278, KAKENHI-PROJECT-15H03025
[Journal Article] TGF-β-induced phosphorylation of Akt and Foxo transcription factors negatively regulates induced regulatory T cell differentiation.2016
- Author(s)
  Kurebayashi Y, Baba Y, Minowa A, Nadya NA, Azuma M, Yoshimura A, Koyasu S, Nagai S.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 480 Issue: 1 Pages: 114-119
- DOI
  10.1016/j.bbrc.2016.09.153
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293400
[Journal Article] A novel hydroxyapatite film coated with ionic silver via inositol hexaphosphate chelation prevents implant-associated infection.2016
- Author(s)
  Funao H, Nagai S, Sasaki A, Hoshikawa T, Tsuji T, Okada Y, Koyasu S, Toyama Y, Nakamura M, Aizawa M, Matsumoto M, Ishii K.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 23238-23238
- DOI
  10.1038/srep23238
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293400, KAKENHI-PROJECT-15H03025
[Journal Article] The RNA Binding Protein Mex-3B Is Required for IL-33 Induction in the Development of Allergic Airway Inflammation.2016
- Author(s)
  Yamazumi Y, Sasaki O, Imamura M, Oda T, Ohno Y, Shiozaki-Sato Y, Nagai S, Suyama S, Kamoshida Y, Funato K, Yasui T, Kikutani H, Yamamoto K, Dohi M, Koyasu S, Akiyama T.
- Journal Title
  
  Cell Rep.
  
  Volume: 16 Issue: 9 Pages: 2456-2471
- DOI
  10.1016/j.celrep.2016.07.062
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293400, KAKENHI-PROJECT-16K14650
[Journal Article] Delayed Propionibacterium acnes surgical site infections occur only in the presence of an implant2016
- Author(s)
  Y. Shiono, K. Ishii, S. Nagai, H. Kakinuma, A. Sasaki, H. Funao, T. Kuramoto1, K. Yoshioka, H. Ishihama, N. Isogai, K. Takeshima, T. Tsuji, Y. Okada, S. Koyasu, M. Nakamura, Yoshiaki Toyama, M. Aizawa, and M. Matsumoto
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 32758-32758
- DOI
  10.1038/srep32758
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H03025, KAKENHI-PROJECT-26293400
[Journal Article] A novel mouse model of soft-tissue infection using bioluminescence imaging allows noninvasive, real-time monitoring of bacterial growth.2014
- Author(s)
  Yoshioka K, Ishii K, Kuramoto T, Nagai S, Funao H, Ishihama H, Shiono Y, Sasaki A, Aizawa M, Okada Y, Koyasu S, Toyama Y, Matsumoto M
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 9 Pages: e106367-e106367
- DOI
  10.1371/journal.pone.0106367
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22229004, KAKENHI-PROJECT-25670235, KAKENHI-PROJECT-26293400
[Journal Article] A unique dermal dendritic cell subset that skews the immune response toward Th2.2013
- Author(s)
  2.Murakami R, Denda-Nagai K, Hashimoto S, Nagai S, Hattori M, Irimura T.
- Journal Title
  
  PLoS One.
  
  Volume: 8 Issue: 9 Pages: e73270-e73270
- DOI
  10.1371/journal.pone.0073270
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23689009, KAKENHI-PROJECT-24790479, KAKENHI-PROJECT-25290071
[Journal Article] CDK inhibitors suppress Th17 and promote iTreg differentiation, and ameliorate experimental autoimmune encephalomyelitis in mice.2013
- Author(s)
  Yoshida H, Kotani H, Kondo T, Tani I, Wei X, Tsuruta S, Kimura A, Asakawa M, Ito M, Nagai S, Yoshimura A.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 435 Issue: 3 Pages: 378-384
- DOI
  10.1016/j.bbrc.2013.04.096
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790479, KAKENHI-PROJECT-25460132
[Journal Article] Role of PI3K/Akt and mTOR complexes in Th17 cell differentiation2013
- Author(s)
  Nagai S, Kurebayashi Y, Koyasu S
- Journal Title
  
  Ann N Y Acad Sci
  
  Volume: 1280 Issue: 1 Pages: 30-4
- DOI
  10.1111/nyas.12059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790479
[Journal Article] TIM-4 glycoprotein-mediated degradation of dying tumor cells by autophagy leads to reduced antigen presentation and increased immune tolerance.2013
- Author(s)
  Baghdadi M, Yoneda A, Yamashina T, Nagao H, Komohara Y, Nagai S, Akiba H, Foretz M, Yoshiyama H, Kinoshita I, Dosaka-Akita H, Takeya M, Viollet B, Yagita H, Jinushi M
- Journal Title
  
  Immunity
  
  Volume: 39 Issue: 6 Pages: 1070-1081
- DOI
  10.1016/j.immuni.2013.09.014
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23130501, KAKENHI-PROJECT-23501283, KAKENHI-PROJECT-23590534, KAKENHI-PROJECT-23591132, KAKENHI-PROJECT-24790479, KAKENHI-PUBLICLY-25112701, KAKENHI-PUBLICLY-25130701, KAKENHI-PROJECT-25293089, KAKENHI-PROJECT-25461503
[Journal Article] Recent advances in understanding the molecular mechanisms of the development and function of Th17 cells.2013
- Author(s)
  Kurebayashi Y, Nagai S, Ikejiri A, Koyasu S.
- Journal Title
  
  Genes to Cells
  
  Volume: 18 Issue: 4 Pages: 247-265
- DOI
  10.1111/gtc.12039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790479
[Journal Article] PI3K-Akt-mTORC1-S6K1/2 axis controls Th17 differentiation by regulating Gfi-1 expression and nuclear translocation of RORγ2012
- Author(s)
  Kurebayashi Y. Nagai S. Ikejiri A. Ohtani M. Ichiyama K. Baba Y. Yamada T. Egami S. Hoshii T. Hirao A. Matsuda S. Koyasu S.
- Journal Title
  
  Cell Reports
  
  Volume: 1 Issue: 4 Pages: 360-373
- DOI
  10.1016/j.celrep.2012.02.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390290, KAKENHI-PROJECT-22229004, KAKENHI-PROJECT-22590439, KAKENHI-PROJECT-22790906, KAKENHI-PUBLICLY-23130507, KAKENHI-PROJECT-23390086, KAKENHI-PROJECT-23650593, KAKENHI-PROJECT-23790546, KAKENHI-PROJECT-24240119, KAKENHI-PROJECT-24790479, KAKENHI-PROJECT-24790967, KAKENHI-PUBLICLY-23118511
[Journal Article] Local effects of regulatory T cells in MUC1 transgenic mice potentiate growth of MUC1 expressing tumor cells in vivo2012
- Author(s)
  Sugiura D, Denda-Nagai K, Takashima M,他全7名
- Journal Title
  
  PLos One
  
  Volume: 7 (9) Issue: 9 Pages: e44770-e44770
- DOI
  10.1371/journal.pone.0044770
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300355, KAKENHI-PROJECT-23689009, KAKENHI-PROJECT-24659029, KAKENHI-PROJECT-24790479
[Journal Article] Autoimmunity against M(2) muscarinic acetylcholine receptor induces myocarditis and leads to a dilated cardiomyopathy-like phenotype2012
- Author(s)
  Yoshizawa, A.
- Journal Title
  
  Eur J Immunol
  
  Volume: 42 Issue: 5 Pages: 1152-1163
- DOI
  10.1002/eji.201142104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229014, KAKENHI-PROJECT-23390086, KAKENHI-PROJECT-24790479
[Journal Article] Listerial invasion protein internalin B promotes the entry into ileal Peyer's patches in vivo.2011
- Author(s)
  Chiba S, Nagai T, Hayashi T, Baba Y, Nagi S, Koyasu S.
- Journal Title
  
  Microbioiogy and Immunology
  
  Volume: 55(2) Pages: 123-129
- NAID
  10031121450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790476
[Journal Article] Listerial invasion protein internalin B promotes the entry into ileal Peyer's patches in vivo.2011
- Author(s)
  Chiba S, Nagai T, Hayashi T, Baba Y, Nagai S, Koyasu S.
- Journal Title
  
  Microbiol Immunol vol.55(2)
  
  Pages: 123-9
- NAID
  10031121450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790476
[Journal Article] Inflammatory cytokines and hypoxia contribute to ^<18>F-FDG uptake by cells involved in pannus formation in rheumatoid arthritis.2009
- Author(s)
  Matsui T, Nakata N, Nagai S, Nakatani A, Takahashi M, Momose T, Ohtomo K, Koyasu S.
- Journal Title
  
  J Nucl Med vol.50(6)
  
  Pages: 920-926
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790476
[Journal Article] Critical Roles of NK and CD8^+ T Cells in Central Nervous System Listeriosis.2009
- Author(s)
  Hayashi T, Nagai S, Fujii H, Baba Y, Ikeda E, Kawase T, Koyasu S.
- Journal Title
  
  J Immunol vol.182(10)
  
  Pages: 6360-6368
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790476
[Journal Article] Critical Roles of NK and CD8^+ T Cells in Central Nervous System Listeriosis.2009
- Author(s)
  Hayashi T, Nagai S, Fujii H, Baba Y, Ikeda E, Kawase T, ^*Koyasu S.
- Journal Title
  
  The Journal of Immunology 182
  
  Pages: 6360-6368
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060021
[Journal Article] Critical roles of NK and CD8+ T cells in CNS listeriosis.2009
- Author(s)
  Hayashi T, Nagai S, Fujii H, Baba Y, Ikeda E, Kawase T, Koyasu S.
- Journal Title
  
  J Immunol (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790364
[Journal Article] Milk fat globule epidermal growth factor-8 blockade triggers tumor destruction through coordinated cell-autonomous and immune-mediated mechanisms.2009
- Author(s)
  Jinushi M, Sato M, Kanamoto A, Itoh A, Nagai S, Koyasu S, Dranoff G, ^*Tahara H.
- Journal Title
  
  The Journal of Experimental Medicine 206
  
  Pages: 1317-1326
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060021
[Journal Article] Bordetella Evades the Host Immune System by Inducing II-10 through a Type III Effector, BopN.2009
- Author(s)
  Nagamatsu K, Kuwae A, Konaka T, Nagai S, Watanabe M, Yoshida S, Mimuro H, Koyasu S, *^Abe A.
- Journal Title
  
  The Journal of Experimental Medicine 206
  
  Pages: 3073-3088
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790476
[Journal Article] Critical roles of NI( and CD8^+ T cells in CNS listeriosis2009
- Author(s)
  Hayashi T, Nagai S, Fujii H, Baba Y, Ikeda E, Kawase T, Koyasu S
- Journal Title
  
  Jlmmunol 182(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790364
[Journal Article] Milk fat globule epidermal growth factor-8 blockade triggers tumor destruction through coordinated cell-autonomous and immune-mediated mechanisms.2009
- Author(s)
  Jinushi M, Sato M, Kanamoto A, Itoh A, Nagai S, Koyasu S, Dranoff G, Tahara H.
- Journal Title
  
  J Exp Med vol.206(6)
  
  Pages: 1317-1326
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790476
[Journal Article] Helicobacter pylori CagA Phosphorylation- Independent Function in Epithelial Proliferation and Inflammation2009
- Author(s)
  Suzuki M, Mimuro H, Kiga K, Fukumatsu M, Ishijima N, Morikawa H, Nagai S, Koyasu S, Gilman RH, Kersulyte D, Berg DE, Sasakawa C.
- Journal Title
  
  Cell Host Microbe 5
  
  Pages: 23-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060021
[Journal Article] Inflammatory cytokines and hypoxia contribute to <18>^F-FDG uptake by cells involved in pannus formation in rheumatoid arthritis.2009
- Author(s)
  Matsui T, Nakata N, Nagai S, *^Nakatani A, Takahashi M, Momose T, Ohtomo K, *^Koyasu S.
- Journal Title
  
  The Journal of Nuclear Medicine 50
  
  Pages: 920-926
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790476
[Journal Article] Inflammatory cytokines and hypoxia contribute to ^<18>F-FDG uptake by cells involved in pannus formation in rheumatoid arthritis.2009
- Author(s)
  Matsui T, Nakata N, Nagai S, ^*Nakatani A, Takahashi M, Momose T, Ohtomo K, ^*Koyasu S.
- Journal Title
  
  The Journal of Nuclear Medicine 50
  
  Pages: 920-926
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060021
[Journal Article] Milk fat globule epidermal growth factor-8 blockade triggers tumor destruction through coordinated cell-autonomous and immune-mediated mechanisms.2009
- Author(s)
  Jinushi M, Sato M, Kanamoto A, Itoh A, Nagai S, Koyasu S, Dranoff G, *^Tahara H.
- Journal Title
  
  The Journal of Experimental Medicine 206
  
  Pages: 1317-1326
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790476
[Journal Article] Bordetella Evades the Host Immune System by Inducing Il-10 through a Type III Effector,BopN.2009
- Author(s)
  Nagamatsu K, Kuwae A, Konaka T, Nagai S, Watanabe M, Yoshida S, Mimuro H, Koyasu S, Abe A.
- Journal Title
  
  J Exp Med vol.206(13)
  
  Pages: 3073-3088
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790476
[Journal Article] Inflammatory cytokine and hypoxia contribute to fluoro2-deoxy glucoseuptake by cells involved in pannus formation in rheumatoid arthritis2009
- Author(s)
  Matsui T, Nakata N, Nakatani A, Nagai S, Koyasu S
- Journal Title
  
  JNucl Med (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790364
[Journal Article] Helicobacter pylori CagA Phosphorylation-Independent Function in Epithelial Proliferation and Inflammation.2009
- Author(s)
  Suzuki M, Mimuro H, Kiga K, Fukumatsu M, Ishijima N, Morikawa H, Nagai S, Koyasu S, Gilman RH, Kersulyte D, Berg DE, Sasakawa C.
- Journal Title
  
  Cell Host Microbe 5(1)
  
  Pages: 23-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790364
[Journal Article] Bordetella Evades the Host Immune System by Inducing I1-10 through a Type III Effector, BopN.2009
- Author(s)
  Nagamatsu K, Kuwae A, Konaka T, Nagai S, Watanabe M, Yoshida S, Mimuro H, Koyasu S, ^*Abe A.
- Journal Title
  
  The Journal of Experimental Medicine 206
  
  Pages: 3073-3088
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060021
[Journal Article] Critical Roles of NK and CD8^+ T Cells in Central Nervous System Listeriosis.2009
- Author(s)
  Hayashi T, Nagai S, Fujii H, Baba Y, Ikeda E, Kawase T, *^Koyasu S.
- Journal Title
  
  The Journal of Immunology 182
  
  Pages: 6360-6368
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790476
[Journal Article] Helicobacter pylori CagA PhosphorylationIndependent Function in Epithelial Proliferation and Inflammation2009
- Author(s)
  Suzuki M, Mimuro H, Kiga K, Fukumatsu M, Ishijima N, Morikawa H, Nagai S, Koyasu S, Gilman RH, Kersulyte D, Berg DE, Sasakawa C
- Journal Title
  
  Cell Host Microbe 5
  
  Pages: 23-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790364
[Journal Article] Critical roles of NK and CD8^+T cells in CNS listeriosis2009
- Author(s)
  Hayashi T, Nagai S, Fujii H, Baba Y, Ikeda E, Kawase T, Koyasu S.
- Journal Title
  
  J Immunol(in press) 182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060021
[Journal Article] Inflammatory cytokines and hypoxia contribute to fluoro-2-deoxy glucose uptake by cells involved in pannus formation in rheumatoid arthritis.2009
- Author(s)
  Matsui T, Nakata N, Nagai S, Nakatani A, Takahashi M, Momose T, Ohtomo K, Koyasu S.
- Journal Title
  
  J Nucl Med (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790364
[Journal Article] mTOR and GSK3 pathways downstream of PI3-kinase differentially regulate LPS-induced IL-12 production in dendritic cells2008
- Author(s)
  Ohtani M, Nagai S, Kondo S, Mizuno S, Nakamura K, Tanabe M, Takeuchi T. Matsuda S. Koyasu S.
- Journal Title
  
  Blood 112
  
  Pages: 635-643
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060021
[Journal Article] mTOR and GSK3 pathways downstream of PI3-kinase differentially regulate LPSinduced IL-12 production in dendritic cells2008
- Author(s)
  Ohtani M, Nagai S, Kondo S, Mizuno S, Nakamura K, Tanabe M, Takeuchi T, Matsuda S, Koyasu S
- Journal Title
  
  Blood 112
  
  Pages: 635-643
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790364
[Journal Article] The role of DC-STAMP in maintenance of immune tolerance through regulation of dendrtic cell function2008
- Author(s)
  Sawatani Y, Miyamoto T, Nagai S, Maruya M, Imai J, Fujita N, Miyamoto K, Ninomiya K, Suzuki T, Iwasaki R, Toyama Y, Koyasu S. Suda T
- Journal Title
  
  Int Immunol 20
  
  Pages: 1259-1268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790364
[Journal Article] The role of DC-STAMP in maintenance of immune tolerance through regulation of dendrtic cell function2008
- Author(s)
  Sawatani Y, Miyamoto T, Nagai S, Maruya M, Imai J, Fujita N, Miyamoto K, Ninomiya K, Suzuki T, Iwasaki R, Toyama Y, Koyasu S, Suda T.
- Journal Title
  
  Int Immunol 20
  
  Pages: 1259-1268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060021
[Journal Article] Identification and expression of human epiglycanin/MUC21 : a novel transmembrane mucin.2008
- Author(s)
  Ito Y, Kamata-Sakurai M, Denda-Nagai K, Nagai S, Tsuiji M, Ishii-Schrade K, Okada K, Goto A, Fukayama M, Irimura T.
- Journal Title
  
  Glycobiology 18(1)
  
  Pages: 74-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790364
[Journal Article] mTOR and GSK3 pathways downstream of PI3-kinase differentially regulate LPS-induced IL-12 production in dendritic cells.2008
- Author(s)
  Ohtani M, Nagai S, Kondo S, Mizuno S, Nakamura K, Tanabe M, Takeuchi T, Matsuda S, Koyasu S.
- Journal Title
  
  Blood 112(3)
  
  Pages: 635-643
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790364
[Journal Article] The role of DC-STAMP in maintenance of immune tolerance through regulation of dendrtic cell function.2008
- Author(s)
  Sawatani Y, Miyamoto T, Nagai S, Maruya M, Imai J, Fujita N, Miyamoto K, Ninomiya K, Suzuki T, Iwasaki R, Toyama Y, Koyasu S, Suda T.
- Journal Title
  
  Int. Immunol 20(10)
  
  Pages: 1259-1268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790364
[Journal Article] Role of Peyer's patches in the induction of Helicobacter pylori-induced gastritis.2007
- Author(s)
  Nagai S, Mimuro H, Yamada T, Baba Y, Moro K, Nochi T, Kiyono H, Suzuki T, Sasakawa C, Koyasu S.
- Journal Title
  
  Proc Natl Acad Sci USA. 104(21)
  
  Pages: 8971-8976
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790364
[Journal Article] Role of Peyer's patches in Helicobacter pylori-induced gastritis2007
- Author(s)
  Nagai, S., et. al.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 104
  
  Pages: 8971-8976
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659141
[Journal Article] Role of Peyer's patches in the induction of Helicobacter pylori-induced gastritis.2007
- Author(s)
  Nagai S, et. al.
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America 104
  
  Pages: 8971-8976
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790364
[Journal Article] Helicobacter pylori dampens gut epithelial self-renewal by inhibiting apoptosis, a bacterial strategy to enhance colonization of the stomach.2007
- Author(s)
  Mimuro H, Suzuki T, Nagai S, Rieder G, Suzuki M, Nagai T, Fujita Y, Nagamatsu K, Ishijima N, Koyasu S, Haas R, Sasakawa C.
- Journal Title
  
  Cell Host Microbe. 2(4)
  
  Pages: 250-263
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790364
[Patent] キラーT細胞の活性化方法2022
- Inventor(s)
  相澤守、新田藍子、野瀬雅人、永井重徳
- Industrial Property Rights Holder
  明治大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-117208
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-21K19930
[Patent] 細胞培養基材、細胞培養基材の製造方法、細胞培養方法、及び細胞培養装置2014
- Inventor(s)
  相澤守，中村まり子，山田清貴，永井重徳
- Industrial Property Rights Holder
  相澤守，中村まり子，山田清貴
- Industrial Property Rights Type
  特許
- Filing Date
  2014-09-22
- Data Source
  KAKENHI-PROJECT-26293400
[Patent] 細胞培養基材、細胞培養基材の製造方法、細胞培養方法、及び細胞培養装置2014
- Inventor(s)
  相澤守・中村まり子・山田清貴・永井重徳
- Industrial Property Rights Holder
  相澤守・中村まり子・山田清貴・永井重徳
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-192763
- Filing Date
  2014-09-22
- Data Source
  KAKENHI-PROJECT-24500531
[Patent] キャリア2007
- Inventor(s)
  小安重夫、永井重徳、笹川千尋、三室仁美
- Industrial Property Rights Holder
  慶應義塾
- Filing Date
  2007-11-14
- Overseas
- Data Source
  KAKENHI-PROJECT-18659141
[Presentation] 養子免疫療法のためのCaO-P2O5 -SiO2 -B2O3系セラミックスの作製と黒色腫に対する抗腫瘍効果の検証2024
- Author(s)
  野瀬雅人, 木造理萌子, 永尾優季, 新田藍子, 鄭允迪, 福田龍一, 永井重徳, 相澤守
- Organizer
  日本セラミックス協会酸素酸塩研究会第4回酸素酸塩材料科学研究会
- Data Source
  KAKENHI-PROJECT-21K19930
[Presentation] 反応焼結法によるホウ素含有アパタイトセラミックスの作製および担がんマウスによる抗腫瘍効果の検証2024
- Author(s)
  大嶋勇輝, 野瀬雅人, 福田龍一. 鄭允迪, 永井重徳, 相澤守
- Organizer
  日本セラミックス協会2024年年会
- Data Source
  KAKENHI-PROJECT-21K19930
[Presentation] Alternation of anti-tumor responses and PD-L1 blockade.2024
- Author(s)
  Chenyang Zhang, Yi Lu, Shigenori Nagai, Miyuki Azuma.
- Organizer
  The 1st International Symposium on Cancer Immunology and Immunotherapy.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06593
[Presentation] A new immune checkpoint molecule ILDR2 expression on CD206+ macrophages is enhanced after repeated antigen-painting onto sublingual mucosa.2024
- Author(s)
  Farzana Sultana, Chenyang Zhang, Miyuki Azuma, Shigenori Nagai.
- Organizer
  第52回日本免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-23K06593
[Presentation] Fabrication of ceramics in the CaO-P2O5-SiO2-B2O3 system for adoptive immunotherapy and their anti-tumour effects2023
- Author(s)
  M. Nose, R. Kizukuri, Y. Nagao, A. Nitta, Y. Zheng, R. Fukuda, S. Nagai, M. Aizawa
- Organizer
  Biomaterials International (BMI) Conference 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19930
[Presentation] Fabrication of ceramics in the CaO-P2O5-SiO2-B2O3 system for adoptive immunotherapy and their anti-tumor effects2023
- Author(s)
  M. Nose, R. Kizukuri, Y. Nagao, A. Nitta, Y. Zheng, R. Fukuda, K. Suzuki, S. Nagai and M. Aizawa
- Organizer
  Symposium and Annual Meeting of the International Society for Ceramics in Medicine (Bioceramics 33)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19930
[Presentation] Fabrication of ceramics in the CaO P 2 O 5 SiO 2 B 2 O 3 system for adoptive immunotherapy and their anti tumor effects2023
- Author(s)
  M. Nose, R. Kizukuri , Y . Nagao , A . Nitta, Y. Zheng, R. Fukuda, K . Suzuki , S. Nagai and M. Aizawa
- Organizer
  Symposium and Annual Meeting of the International Society for Ceramics in Medicine ( Bioceramics 33 )
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06593
[Presentation] ILDR2, a new immune checkpoint molecule, is expressed on CD206+ macrophages in sublingual mucosa.2023
- Author(s)
  Farzana Sultana, Chenyang Zhang, Miyuki Azuma, Shigenori Nagai.
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-23K06593
[Presentation] Fabrication of ceramics in the CaO P2O5 S iO2 B2O3 system for adoptive immunotherapy and their anti tumour effects2023
- Author(s)
  M. Nose, R. Kizukuri, Y. Nagao, A. Nitta, Y. Zheng, R. Fukuda, S. Nagai, M. Aizawa,
- Organizer
  Biomaterials International (BMI) Conference 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06593
[Presentation] Immune checkpoint molecule ILDR2 inhibits anti-tumor immune responses via the accelerated recruitment of monocytes.2023
- Author(s)
  Chenyang Zhang, Yuto Nagatomo, Yi Lu, Shigenori Nagai, Miyuki Azuma.
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K06593
[Presentation] 養子免疫療法のための CaO-P2O5-SiO2-B2O3 系セラミックスの作製と担癌マウスを用いた抗腫瘍効果の検証2023
- Author(s)
  野瀬雅人, 木造理萌子, 永尾優季, 新田藍子, 鄭允迪, 福田龍一, 永井重徳, 相澤守
- Organizer
  日本無機リン化学会第32回無機リン化学討論会
- Data Source
  KAKENHI-PROJECT-21K19930
[Presentation] 養子免疫療法のためのCaO-P2O5-SiO2-B2O3 系セラミックスの作製とその抗腫瘍効果2022
- Author(s)
  野瀬雅人, 木造理萌子, 永尾優季, 新田藍子, 鄭允迪, 永井重徳, 相澤守
- Organizer
  日本セラミックス協会第35回秋季シンポジウム
- Data Source
  KAKENHI-PROJECT-21K19930
[Presentation] Fabrication of boron-containing apatite ceramics via reaction sintering process and their immune functions2022
- Author(s)
  Y. Zheng, M. Nose, R. Fukuda, S. Nagai, M. Aizawa
- Organizer
  20th Asian BioCeramics Symposium 2022 (ABC2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19930
[Presentation] 反応焼結法によるホウ素含有アパタイトセラミックスの作製とその免疫細胞によるin vitro評価2022
- Author(s)
  鄭允迪, 中川大輝, 新田藍子, 永井重徳, 相澤守
- Organizer
  無機マテリアル学会第144回学術講演会
- Data Source
  KAKENHI-PROJECT-21K19930
[Presentation] FGF18 modulates M2-like macrophage polarizationby inducing CCL2-CCR2 signaling in calvarial bone healing2022
- Author(s)
  Worachat Namangkalakul, Shigenori Nagai, Ken-ichi Nakahama, Chengxue Jin, Satoshi Ueha, Kazunari Akiyoshi, Kouji Matsushima, Masaki Takechi and Sachiko Iseki
- Organizer
  Gordon Research Conference -Craniofacial Morphogenesis and Tissue Regeneration-
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H03098
[Presentation] 反応焼結法によるホウ素含有アパタイトセラミックスの作製とその免疫機能2022
- Author(s)
  鄭允迪, 野瀬雅人, 福田龍一, 永井重徳, 相澤守
- Organizer
  第44回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-21K19930
[Presentation] Effects of Indirect Activity of Fibroblast Growth Factor 18 on M2-like Macrophage Polarization in Calvarial Bone Healing2021
- Author(s)
  Worachat Namangkalakul, Shigenori Nagai, Ken-ichi Nakahama, Kazunari Akiyoshi, Masaki Takechi, Sachiko Iseki
- Organizer
  第42回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-21H03098
[Presentation] Gingival keratinocyte-associated immune checkpoint PD-L1 inhibits periodontal inflammation2020
- Author(s)
  Wongtim Keeratika、永井　重徳、奥原　滋、東　みゆき
- Organizer
  第62回歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-18H04066
[Presentation] Binding and functional properties of VSIG4(V-set and Ig domain containing 4)-Ig fusion protein.2020
- Author(s)
  Widyagarini Amrita、永井　重徳、東　みゆき.
- Organizer
  第62回歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-18H04066
[Presentation] Overexpression of gingiva-associated PD-L1 inhibits gingival/periodontal inflammation2020
- Author(s)
  Wongtim Keeratika、池田　恵莉、大野　建州、永井　重徳、奥原　滋、呉　圭哲、東　みゆき.
- Organizer
  第74回日本口腔科学会
- Data Source
  KAKENHI-PROJECT-18H04066
[Presentation] 境界部に限局したCD8+T細胞と制御性T細胞の浸潤を認める同所性マウス舌扁平上皮癌モデル2020
- Author(s)
  加島　義久、西井　直人、立浪　秀剛、永井　重徳、原田　浩之、東　みゆき.
- Organizer
  第79回日本癌学会
- Data Source
  KAKENHI-PROJECT-18H04066
[Presentation] One of PD-1 ligand, PD-L2 induced on Langerhans cells augments cutaneous T cell-mediated immune responses.2019
- Author(s)
  Emi Furusawa, Tatsukuni Ohno, Shigenori Nagai, Takuya Komiyama, Katsunori Kobayashi, Hidetoshi Hamamoto, Michiyo Miyashin, Hiroo Yokozeki, Miyuki Azuma.
- Organizer
  第47回日本免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17H04376
[Presentation] 反応焼結法により作製したホウ素含有アパタイトセラミックスと免疫細胞との相互作用．2019
- Author(s)
  中川大輝，加々見早苗，永井重徳，相澤守．
- Organizer
  第41回日本バイオマテリアル学会大会．
- Data Source
  KAKENHI-PROJECT-17H04376
[Presentation] Differences of tumor-recruiting myeloid cells in murine squamous cell carcinoma influence the efficacy of immunotherapy combined with a TLR7 agonist and PD-L1 blockade.2019
- Author(s)
  Azuma M, Tachinami H, Nishii N, Xia Y, Kashima Y, Nagai S, Li L, Tomihara K, Noguchi M.
- Organizer
  17th IUIS 2019 (International Congress of Immunology)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04066
[Presentation] Identification of a unique macrophage subset induced by repeated antigen painting in sublingual mucosa to regulate T cell tolerance.2019
- Author(s)
  Yue Yang, Shigenori Nagai, Miyuki Azuma
- Organizer
  第47回日本免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17H04376
[Presentation] Silencing of PD-L2 by topical application of small interfering RNA inhibits elicitation of contact hypersensitivity.2019
- Author(s)
  Azuma M, Furusawa E, Nagai S, Yokozeki H.
- Organizer
  17th IUIS 2019 (International Congress of Immunology)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04066
[Presentation] Silencing of PD-L2/B7-DC by topical application of small iInterfering RNA inhibits elicitation of contact hypersensitivity.2019
- Author(s)
  Furusawa E, Ohno T, Nagai S, Noda T, Komiyama T, Kobayashi K, Hamamoto H, Miyashin M, Yokozeki H, Azuma M.
- Organizer
  AAI 2019 (The American Association of Immunologists, Immunology2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04066
[Presentation] Differences of tumor-recruiting myeloid cells in murine squamous cell carcinoma influence the efficacy of immunotherapy combined with a TLR7 agonist and PD-L1 blockade.2019
- Author(s)
  Azuma M, Tachinami H, Nishii N, Xia Y, Kashima Y, Nagai S, Li L, Tomihara K, Noguchi M.
- Organizer
  17th International Congress of Immunology.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04376
[Presentation] PI3K-Akt pathway enhances the differentiation of interleukin 27-induced type 1 regulatory T cells.2019
- Author(s)
  Nagai S, Adiba-Nadya N, Tezuka H, Ohteki T, Matsuda S, Azuma M.
- Organizer
  17th International Congress of Immunology.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04376
[Presentation] Repeated antigen painting induces tolerogenic cells in sublingual mucosa.2019
- Author(s)
  Yang Y, Nagai S, Azuma M.
- Organizer
  17th International Congress of Immunology.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04376
[Presentation] Fabrication of boron-containing apatite ceramics by reaction sintering process and their cellular responses to immunocytes.2019
- Author(s)
  Daiki Nakagawa, Sanae Kagami, Shigenori Nagai, and Mamoru Aizawa.
- Organizer
  The 19th Asian BioCeramics Symposium (ABC2019).
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04376
[Presentation] Silencing of PD-L2 by topical application of small interfering RNA inhibits elicitation of contact hypersensitivity.2019
- Author(s)
  Azuma M, Furusawa E, Nagai S, Yokozeki H.
- Organizer
  17th International Congress of Immunology.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04376
[Presentation] Repeated antigen painting induces tolerogenic cells in sublingual mucosa.2019
- Author(s)
  Yang Y, Nagai S, Azuma M.
- Organizer
  17th IUIS 2019 (International Congress of Immunology)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04066
[Presentation] Identification of a unique macrophage subset induced by repeated antigen painting in sublingual mucosa to regulate T cell tolerance.2019
- Author(s)
  Yang Y, Nagai S, Azuma M.
- Organizer
  第48回日本免疫学会
- Data Source
  KAKENHI-PROJECT-18H04066
[Presentation] Fabrication of boron-containing apatite ceramics with well-controlled chemical composition by reaction sintering method and their cellular response to immunocytes.2019
- Author(s)
  Daiki Nakagawa, Sanae Kagami, Shigenori Nagai, and Mamoru Aizawa.
- Organizer
  The 13th Pacific Rim Conference of Ceramic Societies (PACRIM13).
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04376
[Presentation] One of PD-1 ligand、PD-L2 induced on Langerhans cells augments cutaneous T cell-mediated immune responses.2019
- Author(s)
  Furusawa E, Ohno T, Nagai S, Komiyama T, Kobayashi K, Hamamoto H, Miyashin M, Yokozeki H, Azuma M.
- Organizer
  第48回日本免疫学会
- Data Source
  KAKENHI-PROJECT-18H04066
[Presentation] 抗腫瘍応答における内因性および腫瘍内投与IL-33の機能評価．2018
- Author(s)
  夏玉龍，西井直人，永井重徳，東みゆき，大野建州
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04376
[Presentation] Immunosuppressive status of CD206hl cells appeared in sublingual mucosa2018
- Author(s)
  Yang Yue、永井　重徳、東　みゆき
- Organizer
  第60回歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-18H04066
[Presentation] 2つのマウス扁平上皮癌モデルの癌微小環境におけるミエロイド系細胞の相違とTLR7アゴニストの投与効果2018
- Author(s)
  立浪　秀剛、西井　直人、永井　重徳、加島　義久、冨原　圭、野口　誠、東　みゆき
- Organizer
  第77回日本癌学会
- Data Source
  KAKENHI-PROJECT-18H04066
[Presentation] 抗腫瘍応答における内因性および腫瘍内投与IL-33の機能評価2018
- Author(s)
  夏　玉龍、西井　直人、永井　重徳、東　みゆき、大野　建州
- Organizer
  第77回日本癌学会
- Data Source
  KAKENHI-PROJECT-18H04066
[Presentation] Immunosuppressive status of CD206hi cells appeared in sublingual mucosa.2018
- Author(s)
  Yang Yue, 永井重徳，東みゆき
- Organizer
  第60回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-17H04376
[Presentation] Involvement of CD206+ cells in oral mucosal tolerance2018
- Author(s)
  Yang Y, Nagai S, Azuma M
- Organizer
  第47回日本免疫学会
- Data Source
  KAKENHI-PROJECT-18H04066
[Presentation] 反応焼結法によるホウ素含有アパタイトセラミックスの作製とその免疫細胞応答性.2018
- Author(s)
  中川大輝，木造理萌子，加々見早苗，永井重徳，相澤守．
- Organizer
  第27回無機リン化学討論会.
- Data Source
  KAKENHI-PROJECT-17H04376
[Presentation] Responses of Immune Cells to Hydroxyapatite Ceramics Loaded with Immunostimulators.2018
- Author(s)
  S. Kagami, R. Kizukuri, S. Nagai, and M. Aizawa.
- Organizer
  30th Symposium and Annual Meeting of the International Society for Ceramics in Medicine.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04376
[Presentation] 免疫賦活担持水酸アパタイトセラミックスの作製と免疫細胞応答性．2018
- Author(s)
  加々見早苗，木造理萌子，永井重徳，相澤守．
- Organizer
  第40回日本バイオマテリアル学会大会．
- Data Source
  KAKENHI-PROJECT-17H04376
[Presentation] イノシトールリン酸を表面修飾した水酸アパタイトセラミックスの作製とその免疫細胞応答．2018
- Author(s)
  上野太郎，木造理萌子，山田清貴，永井重徳，相澤守．
- Organizer
  第22回生体関連セラミックス討論会．
- Data Source
  KAKENHI-PROJECT-17H04376
[Presentation] ２つのマウス扁平上皮癌モデルの癌微小環境におけるミエロイド系細胞の相違とTLR7アゴニストの投与効果．2018
- Author(s)
  立浪秀剛，西井直人，永井重徳，加島義久，冨原圭，野口誠，東みゆき
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04376
[Presentation] Systemic administration of a TLR7 agonist attenuates regulatory T cells by dendritic cell modification and overcomes resistance to PD-L1 blockade therapy2018
- Author(s)
  Nishii N, Tachinami H, Kondo Y, Xia Y, Kashima Y, Ohno T, Nagai S, Li L, Lau W, Harada H, Azuma M
- Organizer
  15th International Symposium on Dendritic Cells
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04066
[Presentation] Involvement of CD206+ cells in oral mucosal tolerance.2018
- Author(s)
  Yue Yang, Shigenori Nagai, Miyuki Azuma.
- Organizer
  第47回日本免疫学会総会・学術集会．
- Data Source
  KAKENHI-PROJECT-17H04376
[Presentation] Fabrication of boron-containing apatite ceramics by reaction sintering method and their cellular responses of immunocytes.2018
- Author(s)
  D. Nakagawa, R. Kizukuri, S. Kagami, S. Nagai and M. Aizawa.
- Organizer
  The 18th Asian Bioceramics Symposium.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04376
[Presentation] reparation of Hydroxyapatite Ceramics Loaded with Various Immunostimulators and Their Responses to Immune Cells.2017
- Author(s)
  Sanae Kagami, Rihoko Kizukuri, Shigenori Nagai, and Mamoru Aizawa.
- Organizer
  The 15th International Conference on Advanced Materials.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04376
[Presentation] Site-specific regulation of oral mucosa-recruiting CD8+ T cells -Comparison of contact allergy between skin and oral mucosa-.2017
- Author(s)
  Worawalun HIRUNWIDCHAYARAT, Emi FURUSAWA, Tatsukuni OHNO, Shigenori NAGAI, Miyuki AZUMA.
- Organizer
  第46回日本免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17H04376
[Presentation] PI3K-Akt pathway enhances type 1 regulatory T cell differentiation induced by IL-27.2017
- Author(s)
  １．Shigenori Nagai, Niken Adiba Nadya, Hiroyuki Tezuka, Toshiaki Ohteki, Satoshi Matsuda, Miyuki Azuma.
- Organizer
  第46回日本免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17H04376
[Presentation] 免疫系に積極的に働きかけるCaO-P2O5-SiO2-B2O3系ガラスセラミックスの作製とその表面特性2017
- Author(s)
  木造理萌子, 本田みちよ, 永井重徳, 相澤守
- Organizer
  無機マテリアル学会　第135回学術講演会
- Data Source
  KAKENHI-PROJECT-15H03025
[Presentation] Effect of surface roughness on immune cells of hydroxyapatite ceramics modified with inositol phosphate2017
- Author(s)
  T. Ueno, R. Kizukuri, K. Yamada, S. Nagai and M. Aizawa
- Organizer
  The 17th Asian BioCeramics Symposium (ABC2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03025
[Presentation] Preparation of hydroxyapatite ceramics loaded with various immunostimulators and their responses to immune cells2017
- Author(s)
  S. Kagami, R. Kizukuri, S. Nagai, and M. Aizawa
- Organizer
  The 15th International Conference on Advanced Materials (IUMRS-ICA 2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03025
[Presentation] イノシトールリン酸を表面修飾した水酸アパタイトセラミックスの免疫細胞応答性．2017
- Author(s)
  上野太郎，木造理萌子，山田清貴，永井重徳，相澤守．
- Organizer
  第26回無機リン化学討論会．
- Data Source
  KAKENHI-PROJECT-17H04376
[Presentation] イノシトールリン酸を修飾した水酸アパタイト焼結体の免疫細胞に与える表面粗さの影響2017
- Author(s)
  上野太郎, 木造理萌子, 山田清貴, 永井重徳, 相澤守
- Organizer
  第39回バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-15H03025
[Presentation] 上皮系細胞におけるB7-H1発現に関わるシグナル探索．2017
- Author(s)
  金キン，永井重徳，東みゆき．
- Organizer
  第59回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-17H04376
[Presentation] 免疫賦活剤を担持させた水酸アパタイトセラミックスの免疫細胞応答性2017
- Author(s)
  加々見早苗, 木造理萌子, 永井重徳, 相澤守
- Organizer
  第39回バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-15H03025
[Presentation] CaO-P2O5-SiO2-B2O3系ガラスセラミックスと免疫細胞との相互作用2017
- Author(s)
  木造理萌子, 本田みちよ, 永井重徳, 相澤守
- Organizer
  第39回バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-15H03025
[Presentation] Development of immunoceramics in the CaO-P2O5-SiO2-B2O3 system and their cellular responses2017
- Author(s)
  R. Kizukuri, K. Yamada, M. Honda, S. Nagai and M. Aizawa
- Organizer
  Bioceramics 29, The International Society for Ceramics in Medicine (ISCM)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03025
[Presentation] 種々の免疫賦活剤を担持させた水酸アパタイトセラミックスの薬剤徐放特性とその免疫細胞応答性2017
- Author(s)
  加々見早苗, 木造理萌子, 永井重徳, 相澤守
- Organizer
  無機マテリアル学会　第135回学術講演会
- Data Source
  KAKENHI-PROJECT-15H03025
[Presentation] PI3K-Akt pathway enhances Tr1 differentiation induced by IL-27.2017
- Author(s)
  Shigenori Nagai, Niken Adiba Nadya, Hiroyuki Tezuka, Toshiaki Ohteki, Satoshi Matsuda, Miyuki Azuma.
- Organizer
  The 5th Annual Meeting of the International Cytokine and Interferon Society (Cytokines 2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04376
[Presentation] PI3K-Akt経路はIL-27誘導Tr1細胞分化を増強する．第59回歯科基礎医学会学術大会，2017
- Author(s)
  Nadya Niken Adiba，東みゆき，永井重徳．
- Organizer
  第59回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-17H04376
[Presentation] イノシトールリン酸を表面修飾した水酸アパタイトセラミックスの免疫細胞応答性2017
- Author(s)
  上野太郎, 木造理萌子, 山田清隆, 永井重徳，相澤守
- Organizer
  第26回無機リン化学討論会
- Data Source
  KAKENHI-PROJECT-15H03025
[Presentation] 口腔接触アレルギーにおける粘膜局所でのCD8+ T細胞の不活化．2017
- Author(s)
  Hirunwidchayarat Worawalun，古澤慧美，Kang Siwen，大野建州，永井重徳,　東みゆき．
- Organizer
  第59回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-17H04376
[Presentation] Development of Immunoceramics in the CaO-P2O5-SiO2-B2O3 System and their Cellular Responses.2017
- Author(s)
  Rihoko Kizukuri, Kiyotaka Yamada, Michiyo Honda, Shigenori Nagai and Mamoru Aizawa.
- Organizer
  29th Symposium and Annual Meeting of the International Society for Ceramics in Medicine.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04376
[Presentation] Effect of surface roughness on immune cells of hydroxyapatite ceramics modified with inositol phosphate.2017
- Author(s)
  Taro Ueno, Rihoko Kizukuri, Kiyotaka Yamada, Shigenori Nagai, and Mamoru Aizawa.
- Organizer
  17th Asian BioCeramics Symposium 2017.
- Data Source
  KAKENHI-PROJECT-17H04376
[Presentation] CaO-P2O5-SiO2-B2O3 系ガラスセラミックスの免疫細胞応答性2016
- Author(s)
  木造理萌子, 山田清貴, 本田みちよ, 永井重徳, 相澤守
- Organizer
  無機マテリアル学会第132回学術講演会
- Place of Presentation
  千葉県船橋市
- Year and Date
  2016-06-02
- Data Source
  KAKENHI-PROJECT-15H03025
[Presentation] Cellular responses of immune cells to glass ceramics in the CaO-P2O5-SiO2-B2O3 system2016
- Author(s)
  R. Kizukuri, K. Yamada, M. Honda, S. Nagai and M. Aizawa
- Organizer
  16th Asian BioCeramics Symposium (ABC2016)
- Place of Presentation
  Brisbane, Australia
- Year and Date
  2016-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03025
[Presentation] CaO-P2O5-SiO2-B2O3系ガラスセラミックスの免疫細胞応答性．2016
- Author(s)
  木造理萌子，山田清貴，本田みちよ，永井重徳，相澤守．
- Organizer
  無機マテリアル学会第132回講演会．
- Place of Presentation
  船橋市民文化創造館　千葉県船橋市
- Year and Date
  2016-06-02
- Data Source
  KAKENHI-PROJECT-26293400
[Presentation] Features of oral mucosal inflammation-comparative studies with skin inflammation-2016
- Author(s)
  Hirunwidchayarat Worawalun, Ohno Tatsukuni, Kang Siwen, Nagai Sgigenori, Tomura Michio, Azuma Miyuki
- Organizer
  第.45回日本免疫学会
- Place of Presentation
  沖縄コンベンションセンター（沖縄県宜野湾市）
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-26253086
[Presentation] Features of oral mucosal inflammation -comparative studies with skin inflammation-.2016
- Author(s)
  Worawalun Hirunwidchayarat, Tatsukuni Ohno, Siwen Kang, Shigenori Nagai, Michio Tomura, Miyuki Azuma
- Organizer
  第45回日本免疫学会総会・学術集会
- Place of Presentation
  沖縄コンベンションセンター　沖縄県宜野湾市
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-26293400
[Presentation] Tr1分化におけるPI3Kの役割．2016
- Author(s)
  Niken Adiba Nadya, 東みゆき，永井重徳
- Organizer
  第58回歯科基礎医学会学術大会
- Place of Presentation
  札幌コンベンションセンター　北海道札幌市
- Year and Date
  2016-08-24
- Data Source
  KAKENHI-PROJECT-26293400
[Presentation] Responses of Immune Cells Derived from Mouse Spleen to Hydroxyapatite Ceramics Surface-modified with Inositol Phosphate and Their Morphology2016
- Author(s)
  M. Aizawa, K. Yamada, M. Honda, S. Nagai
- Organizer
  10th World Biomaterials Congress
- Place of Presentation
  Montreal, Canada
- Year and Date
  2016-05-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03025
[Presentation] CELLULAR RESPONSES OF IMMUNE CELLS TO GLASS CERAMICS IN THE CaO-P2O5-SiO2-B2O3 SYSTEM.2016
- Author(s)
  Rihoko Kizukuri, Kiyotaka Yamada, Michiyo Honda, Shigenori Nagai and Mamoru Aizawa.
- Organizer
  16th Australasian BioCeramics Symposium.
- Place of Presentation
  Brisbane, Australia.
- Year and Date
  2016-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293400
[Presentation] Regulation of IL-10 production from IL-27-induced Tr1 cells by PI3K-Akt pathway.2016
- Author(s)
  Adiba Nadya Niken, Miyuki Azuma, Shigenori Nagai
- Organizer
  第45回日本免疫学会総会・学術集会
- Place of Presentation
  沖縄コンベンションセンター　沖縄県宜野湾市
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-26293400
[Presentation] Phosphorylation of Akt and Foxos induced by TGF-β negatively regulates the differentiation of induced regulatory T cells.2016
- Author(s)
  Shigenori Nagai, Yutaka Kurebayashi, Yukiko Baba, Akiko Minowa, Miyuki Azuma, Akihiko Yoshimura, Shigeo Koyasu.
- Organizer
  16th International Congress of Immunology
- Place of Presentation
  Melbourne, Australia.
- Year and Date
  2016-08-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293400
[Presentation] 免疫系に積極的に働きかける新規なバイオセラミックスの創製とその免疫細胞応答性2016
- Author(s)
  木造理萌子, 山田清貴, 本田みちよ, 永井重徳, 相澤守
- Organizer
  日本バイオマテリアル学会シンポジウム2016
- Place of Presentation
  福岡市福岡国際会議場
- Year and Date
  2016-11-21
- Data Source
  KAKENHI-PROJECT-15H03025
[Presentation] 口腔粘膜炎症において局所に集積するT細胞の解析．2016
- Author(s)
  Hirunwidchayarat Worawalun，大野建州，Kang Siwen，永井重徳，東みゆき
- Organizer
  第58回歯科基礎医学会学術大会
- Place of Presentation
  札幌コンベンションセンター　北海道札幌市
- Year and Date
  2016-08-24
- Data Source
  KAKENHI-PROJECT-26293400
[Presentation] 口腔粘膜炎症において局所に集積するＴ細胞の解析2016
- Author(s)
  Hirunwidchayarat Worawalun、大野　建州、Kang Siwen、永井　重徳、東　みゆき
- Organizer
  第58回歯科基礎医学会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2016-08-24
- Data Source
  KAKENHI-PROJECT-26253086
[Presentation] イノシトールリン酸を表面修飾した水酸アパタイトセラミックスに対するマウス脾臓由来免疫細胞の応答性．2015
- Author(s)
  山田清貴，中村まり子，永井重徳，本田みちよ，相澤守
- Organizer
  セラミックス協会第28回秋季シンポジウム
- Place of Presentation
  富山大学（富山県富山市）
- Year and Date
  2015-09-16
- Data Source
  KAKENHI-PROJECT-26293400
[Presentation] 咀嚼粘膜上皮における抑制共刺激分子 B7-H1（CD274）の選択的制御2015
- Author(s)
  康　思えん、大野　建州、永井　重徳、東　みゆき
- Organizer
  第69回日本口腔科学会
- Place of Presentation
  大阪国際会議場(大阪府大阪市）
- Year and Date
  2015-05-13
- Data Source
  KAKENHI-PROJECT-26253086
[Presentation] 咀嚼粘膜に発現する B7-H1 は過度な免疫応答による損傷を保護している2015
- Author(s)
  康　思えん、大野建州、永井重徳、東みゆき
- Organizer
  第57回歯科基礎医学会
- Place of Presentation
  新潟コンベンションセンター(新潟県新潟市）
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-26253086
[Presentation] 合成樹脂製インプラントにおける新規抗菌加工の安全性評価―細胞毒性とバイオメカニクス的検討―．2015
- Author(s)
  石濱寛子, 石井賢, 柿沼祐亮, 塩野雄太, 蔵本哲也, 吉岡研之, 船尾陽生, 永井重徳, 佐々木文, 相澤守, 岡田保典, 小安重夫, 松本守雄, 中村雅也
- Organizer
  第30回日本整形外科学会基礎学術集会
- Place of Presentation
  富山国際会議場（富山県富山市）
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-26293400
[Presentation] Selective regulation in expression of Co-inhibitory molecule B7-H1/PD-L1 masticatory mucosae2015
- Author(s)
  Kang S, OhnoT, Nagai S, Azuma M
- Organizer
  ICMI 2015
- Place of Presentation
  Berlin,Germany
- Year and Date
  2015-07-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253086
[Presentation] Recruiting T cells to the oral mucosa under the inflammatory condition.2015
- Author(s)
  Worawalun Hirunwidchayarat, Tatsukuni Ohno, Siwen Kang, Shigenori Nagai, Miyuki Azuma
- Organizer
  第44回日本免疫学会総会・学術集会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-26293400
[Presentation] イノシトールリン酸を表面修飾した水酸アパタイトセラミックス上で培養したマウス脾臓由来免疫細胞の形態観察2015
- Author(s)
  山田清貴・中村まり子・永井重徳・本田みちよ・相澤守
- Organizer
  日本セラミックス協会第28回秋季シンポジウム
- Place of Presentation
  富山大学五福キャンパス
- Year and Date
  2015-09-16
- Data Source
  KAKENHI-PROJECT-15H03025
[Presentation] 水酸アパタイトおよび炭酸含有アパタイトに対するマクロファージ接着が引き起こす生体反応の相違2015
- Author(s)
  井ヶ田一貴・永井亜希子・相澤守・山下仁大
- Organizer
  日本無機リン化学会第25回無機リン化学討論会
- Place of Presentation
  山形大学米沢キャンパス
- Year and Date
  2015-09-28
- Data Source
  KAKENHI-PROJECT-15H03025
[Presentation] Masticatory mucosa-associated B7-H1 limits mucosal tissue damage.2015
- Author(s)
  Siwen Kang, Tatsukuni Ohno, Shigenori Nagai, Miyuki Azuma
- Organizer
  第44回日本免疫学会総会・学術集会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-26293400
[Presentation] 合成樹脂製インプラントにおける新規抗菌開発法の開発．2015
- Author(s)
  石濱寛子, 石井賢, 柿沼祐亮, 塩野雄太, 蔵本哲也, 吉岡研之, 船尾陽生, 永井重徳,　佐々木文, 相澤守, 岡田保典, 小安重夫, 松本守雄,　中村雅也
- Organizer
  第30回日本整形外科学会基礎学術集会
- Place of Presentation
  富山国際会議場（富山県富山市）
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-26293400
[Presentation] Masticatory mucosa-associated B7-H1 limits mucosal tissue damage2015
- Author(s)
  Kang S, Ohno T, Nagai S, Azuma M
- Organizer
  第44回日本免疫学会
- Place of Presentation
  札幌コンベンションセンター(北海道札幌市）
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-26253086
[Presentation] Morphological Observation of Immune Cells Derived from Mouse Spleen to Hydroxyapatite Ceramics Surface-modified with Inositol Phosphate2015
- Author(s)
  K. Yamada, M. Nakamura, S. Nagai, M. Honda, M. Aizawa
- Organizer
  27th Symposium and Annual Meeting of the International Society for Ceramics in Medicine (27 Bioceramics)
- Place of Presentation
  Bali, Indonesia
- Year and Date
  2015-10-27
- Data Source
  KAKENHI-PROJECT-15H03025
[Presentation] Role of PI3K in Tr1 cell differentiation.2015
- Author(s)
  Adiba Nadya Niken, Miyuki Azuma, Shigenori Nagai
- Organizer
  第44回日本免疫学会総会・学術集会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-26293400
[Presentation] Morphological Observation of Immune Cells Derived from Mouse Spleen to Hydroxyapatite Ceramics Surface-Modified with Inositol Phosphate.2015
- Author(s)
  Kiyotaka Yamada, Mariko Nakamura, Shigenori Nagai, Michiyo Honda, Mamoru Aizawa
- Organizer
  Bioceramics 27th Symphosium and Annual Meeting of the International Society for Ceramics in Medicine
- Place of Presentation
  Bali, Indonesia.
- Year and Date
  2015-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293400
[Presentation] Comparison of cytokines secretions from macrophage cultured on hydroxyapatite and carbonated apatite dense ceramics2015
- Author(s)
  K. Igeta, K. Nozaki, M. Aizawa, K. Yamashita, and A. Nagai
- Organizer
  Pacifichem 2015
- Place of Presentation
  Hawaii convention Center, Honolulu, Hawaii, USA
- Year and Date
  2015-12-15
- Data Source
  KAKENHI-PROJECT-15H03025
[Presentation] ホウ素含有アパタイトセラミックスと共存培養したマウス脾臓由来T, B, NK 細胞の細胞比率とその免疫評価2013
- Author(s)
  中村まり子・永井重徳・相澤守
- Organizer
  日本セラミックス協会第26回秋季シンポジウム
- Place of Presentation
  信州大学（長野キャンパス）
- Data Source
  KAKENHI-PROJECT-24500531
[Presentation] Development of a novel antimicrobial-coated biomedical polymer.2013
- Author(s)
  Ishihama H, Ishii K, Nagai S, Kakinuma H, Sasaki A, Yoshioka K, Kuramoto T, Shiono Y, Aizawa M, Okada Y, Koyasu S, Toyama Y, Matsumoto M.
- Organizer
  The International Society for the Study of Lumbar Spine (ISSLS) 2013.
- Place of Presentation
  Scottsdale, Arizona, USA
- Data Source
  KAKENHI-PROJECT-24790479
[Presentation] The pathogenesis of pulmonary alveolar proteinosis in PI3K deficient mice.2013
- Author(s)
  Shigenori Nagai, Akihiro Yoshizawa, Yukiko Baba, Taketo Yamada, Tomoyasu Nishimura, Shigeo Koyasu
- Organizer
  第42回日本免疫学会総会・学術集会
- Place of Presentation
  幕張メッセ（千葉県千葉市）
- Data Source
  KAKENHI-PROJECT-24790479
[Presentation] The pathogenesis of pulmonary alveolar proteinosis in PI3K deficient mice2013
- Author(s)
  Shigenori Nagai, Akihiro Yoshizawa, Yukiko Baba, Taketo Yamada, Tomoyasu Nishimura, Shigeo Koyasu
- Organizer
  第42回日本免疫学会総会・学術集会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-24790479
[Presentation] ホウ素含有アパタイトセラミックスの作製とその免疫細胞応答性2013
- Author(s)
  中村まり子・庄志・永井重徳・相澤守
- Organizer
  第51回セラミックス基礎科学討論会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-24500531
[Presentation] Cellular response of immunocyte to boron - containing apatite ceramics2013
- Author(s)
  Nakamura M, Zhuang Z, Umeda R, Nagai S, Aizawa M
- Organizer
  The 2nd International Symposium on Inorganic and Environmental Materials (ISIEM) 2013
- Place of Presentation
  Rennes, France
- Data Source
  KAKENHI-PROJECT-24790479
[Presentation] Cellular response of immunocyte to boron-containing apatite ceramics (Best Poster Award受賞)2013
- Author(s)
  Mariko Nakamura, Zhi Zhuang, Ryo Umeda, Shigenori Nagai, Mamoru Aizawa
- Organizer
  International Symposium on Inorganic and Environmental Material 2013（ISIEM2013）
- Place of Presentation
  Rennes, France
- Data Source
  KAKENHI-PROJECT-24500531
[Presentation] Development of a novel antimicrobial - coated biomedical polymer2013
- Author(s)
  Ishihama H, Ishii K, Nagai S, Kakinuma H, Sasaki A, Yoshioka K, Kuramoto T, Shiono Y, Aizawa M, Okada Y, Koyasu S, Toyama Y, Matsumoto M
- Organizer
  The International Society for the Study of Lumbar Spine (ISSLS)
- Place of Presentation
  Scottsdale, Arizona, USA
- Data Source
  KAKENHI-PROJECT-24790479
[Presentation] Resident memory T cells in epidermis require hair follicle-derived cytokines for survival.2013
- Author(s)
  Takeya Adachi, Kazuyo Moro, Shigenori Nagai, Masayuki Amagai, Keisuke Nagao.
- Organizer
  第42回日本免疫学会総会・学術集会
- Place of Presentation
  幕張メッセ（千葉県千葉市）
- Data Source
  KAKENHI-PROJECT-24790479
[Presentation] 超音波照射はインプラント表面のバイオフィルムを除去しインプラント関連感染症(IAI)の発症を予防する2013
- Author(s)
  吉岡研之、石井賢、永井重徳、柿沼祐亮、佐々木文、相澤守、岡田保典、小安重夫、戸山芳昭、松本守雄
- Organizer
  第25回整形外科超音波学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2013-07-06
- Data Source
  KAKENHI-PROJECT-24790479
[Presentation] Development of pulmonary alveolar proteinosis in PI3K deficient mice.2013
- Author(s)
  Akihiro Yoshizawa, Shigenori Nagai, Yukiko Baba, Tomoyasu Nishimura, Taketo Yamada, Shigeo Koyasu
- Organizer
  The Joint International Meeting of The 78th JSICR and The 21st MMCB
- Place of Presentation
  都市センターホテル（東京都千代田区）
- Data Source
  KAKENHI-PROJECT-24790479
[Presentation] A comparison of biofilm formation in various metal materials2013
- Author(s)
  Yosihoka K, Ishii K, Nagai S, Kakinuma H, Kuramoto T, Sasaki A, Aizawa M, Okada Y, Koyasu S, Toyama Y, Matsumoto M
- Organizer
  The International Society for the Study of Lumbar Spine (ISSLS) 2013
- Place of Presentation
  Scottsdale, Arizona, USA
- Data Source
  KAKENHI-PROJECT-24790479
[Presentation] A comparison of biofilm formation in various metal materials.2013
- Author(s)
  Yosihoka K, Ishii K, Nagai S, Kakinuma H, Kuramoto T, Sasaki A, Aizawa M, Okada Y, Koyasu S, Toyama Y, Matsumoto M.
- Organizer
  The International Society for the Study of Lumbar Spine (ISSLS) 2013.
- Place of Presentation
  Scottsdale, Arizona, USA
- Data Source
  KAKENHI-PROJECT-24790479
[Presentation] 超音波照射はインプラント表面のバイオフィルムを除去しインプラント関連感染症 (IAI) の発症を予防する2013
- Author(s)
  吉岡研之、石井賢、永井重徳、柿沼祐亮、佐々木文、相澤守、岡田保典、小安重夫、戸山芳昭、松本守雄
- Organizer
  第25回整形外科超音波学会学術集会
- Place of Presentation
  ウエスティンナゴヤキャッスル（愛知県名古屋市）
- Data Source
  KAKENHI-PROJECT-24790479
[Presentation] Cellular response of immunocyte to boron-containing apatite ceramics.2013
- Author(s)
  Nakamura M, Zhuang Z, Umeda R, Nagai S, Aizawa M.
- Organizer
  The 2nd International Symposium on Inorganic and Environmental Materials (ISIEM) 2013.
- Place of Presentation
  Rennes, France
- Data Source
  KAKENHI-PROJECT-24790479
[Presentation] Propionibacterium acnes causes delayed surgical site infection only in the presence of implant.2013
- Author(s)
  Shiono Y, Ishii K, Nagai S, Kuramoto T, Yoshioka K, Ishihama H, Funao H, Kakinuma H, Sasaki A, Aizawa M, Okada Y, Koyasu S, Toyama Y, Matsumoto M.
- Organizer
  The International Society for the Study of Lumbar Spine (ISSLS) 2013.
- Place of Presentation
  Scottsdale, Arizona, USA
- Data Source
  KAKENHI-PROJECT-24790479
[Presentation] Resident memory T cells in epidermis require hair follicle - derived cytokines for survival2013
- Author(s)
  Takeya Adachi, Kazuyo Moro, Shigenori Nagai, Masayuki Amagai, Keisuke Nagao
- Organizer
  第42回日本免疫学会総会・学術集会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-24790479
[Presentation] Propionibacterium acnes causes delayed surgical site infection only in the presence of implant2013
- Author(s)
  Shiono Y, Ishii K, Nagai S, Kuramoto T, Yoshioka K, Ishihama H, Funao H, Kakinuma H, Sasaki A, Aizawa M, Okada Y, Koyasu S, Toyama Y, Matsumoto M
- Organizer
  The International Society for the Study of Lumbar Spine (ISSLS) 2013
- Place of Presentation
  Scottsdale, Arizona, USA
- Data Source
  KAKENHI-PROJECT-24790479
[Presentation] Development of pulmonary alveolar proteinosis in PI3K deficient mice2013
- Author(s)
  Akihiro Yoshizawa, Shigenori Nagai, Yukiko Baba, Tomoyasu Nishimura, Taketo Yamada, Shigeo Koyasu
- Organizer
  The Joint International Meeting of The 78^<th> Meeting of the Japanese Society of Interferon and Cytokine Research and The 21^<st> International Symposium on Molecular Cell Biology of Macrophages 2013
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-24790479
[Presentation] Regulatory role of dendritic cells in postinfarction healing and left ventricular remodeling.2012
- Author(s)
  Atsushi Anzai, Toshihisa Anzai, Shigenori Nagai, Shigeo Koyasu and Keiichi Fukuda
- Organizer
  20th International Symposium on Molecular Cell Biology of Macrophages 2012
- Place of Presentation
  東京大学山上会館
- Data Source
  KAKENHI-PROJECT-24790479
[Presentation] PI3K-Akt-mTORC1-S6K経路はTh17分化を制御する2012
- Author(s)
  永井重徳,紅林泰,池尻藍,大谷真志,馬場夕紀子,星居孝之,平尾敦,松田達志,小安重夫
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24790479
[Presentation] TIM-4 blockade augments therapeutic efficacy of chemotherapy by immune-mediated mechanisms2012
- Author(s)
  Baghdadi Muhammad, Shigeki Chiba, Hisaya Akiba, Hideo Yagita, Shigenori Nagai, Masahisa Jinushi
- Organizer
  第41回日本免疫学会総会・学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24790479
[Presentation] PI3K-Akt-mTORC1-S6K1/2 Axis Controls Th17 Differentiation．2012
- Author(s)
  Shigenori Nagai, Yutaka Kurebayashi, Ai Ikejiri, Masashi Ohtani, Kenji Ichiyama, Yukiko Baba, Taketo Yamada, Shohei Egami, Takayuki Hoshii, Atsushi Hirao, Satoshi Matsuda, Shigeo Koyasu
- Organizer
  Inositol Phospholipid Signaling in Physiology and Disease, New York Academy of Sciences
- Place of Presentation
  World Trade Center Building, New York, USA
- Invited
- Data Source
  KAKENHI-PROJECT-24790479
[Presentation] 獲得免疫系におけるmTORC1シグナルの役割2012
- Author(s)
  松田達志,永井重徳,星居孝之,小安重夫,平尾敦,大谷真志
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24790479
[Presentation] 樹状細胞移入による新規コラーゲン誘導関節炎モデルの確立2012
- Author(s)
  永井重徳,小安重夫
- Organizer
  第56回日本リウマチ学会総会・学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790479
[Presentation] 獲得免疫系におけるmTORC1シグナルの役割2012
- Author(s)
  松田達志，永井重徳，星居孝之，小安重夫，平尾敦，大谷真志
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡国際会議場
- Invited
- Data Source
  KAKENHI-PROJECT-24790479
[Presentation] Role of TLRs in the induction of collagen-induced arthritis2012
- Author(s)
  Midori Iso, Shigenori Nagai, Shigeo Koyasu
- Organizer
  The 12th International Symposium on Dendritic Cells
- Place of Presentation
  Daegu, Korea
- Data Source
  KAKENHI-PROJECT-24790479
[Presentation] Recognition of amphiphilic acylglucoside derived from Helicobacter pylori by C-type lectin receptor Mincle2012
- Author(s)
  Masahiro Nagata, Michio Shimamura, Eri Ishikawa, Shigenori Nagai, Shigeo Koyasu, Sho Yamasaki
- Organizer
  第41回日本免疫学会総会・学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24790479
[Presentation] TIM-4 blockade augments therapeutic efficacy of chemotherapy by immune-mediated mechanisms.2012
- Author(s)
  Baghdadi Muhammad, Shigeki Chiba, Hisaya Akiba, Hideo Yagita, Shigenori Nagai, Masahisa Jinushi
- Organizer
  第41回日本免疫学会総会・学術集会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-24790479
[Presentation] Role of TLRs in the induction of collagen-induced arthritis.2012
- Author(s)
  Midori Iso, Shigenori Nagai, Shigeo Koyasu
- Organizer
  第41回日本免疫学会総会・学術集会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-24790479
[Presentation] PI3K-Akt-mTORC1-S6K1/2 Axis Controls Th17 Differentiation2012
- Author(s)
  Shigenori Nagai, Yutaka Kurebayashi, Ai Ikejiri, Masashi Ohtani, Kenji Ichiyama, Yukiko Baba, Taketo Yamada, Shohei Egami, Takayuki Hoshii, Atsushi Hirao, Satoshi Matsuda, Shigeo Koyasu
- Organizer
  Inositol Phospholipid Signaling in Physiology and Disease, New York Academy of Sciences
- Place of Presentation
  NY,USA
- Data Source
  KAKENHI-PROJECT-24790479
[Presentation] Regulatory role of dendritic cells in postinfarction healing and left ventricular remodeling2012
- Author(s)
  Atsushi Anzai, Toshihisa Anzai, Shigenori Nagai, Shigeo Koyasu and Keiichi Fukuda
- Organizer
  20th International Symposium on Molecular Cell Biology of Macrophages 2012
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-24790479
[Presentation] PI3K-Akt-mTORC1-S6K経路はTh17分化を制御する2012
- Author(s)
  永井重徳，紅林泰，池尻藍，大谷真志，馬場夕紀子，星居孝之，平尾敦，松田達志，小安重夫
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-24790479
[Presentation] Role of TLRs in the induction of collagen-induced arthritis2012
- Author(s)
  Midori Iso, Shigenori Nagai, Shigeo Koyasu
- Organizer
  第41回日本免疫学会総会・学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24790479
[Presentation] Recognition of amphiphilic acylglucoside derived from Helicobacter pylori by C-type lectin receptor Mincle.2012
- Author(s)
  Masahiro Nagata, Michio Shimamura, Eri Ishikawa, Shigenori Nagai, Shigeo Koyasu, Sho Yamasaki
- Organizer
  第41回日本免疫学会総会・学術集会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-24790479
[Presentation] PI3K-Akt-mTORC1-S6K1/2経路はGfi1の発現およびRORの核移行を調節することによりTh17分化を制御する2012
- Author(s)
  永井重徳,紅林泰,大谷真志,松田達志,小安重夫
- Organizer
  第22回Kyoto T cell Conference
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24790479
[Presentation] Role of TLRs in the induction of collagen-induced arthritis.2012
- Author(s)
  Midori Iso, Shigenori Nagai, Shigeo Koyasu
- Organizer
  The 12th International Symposium on Dendritic Cells
- Place of Presentation
  EXCO, Daegu, Korea
- Data Source
  KAKENHI-PROJECT-24790479
[Presentation] Establishment of a novel collagen-induced arthritis model by manipulating dendritic cells.2010
- Author(s)
  Shigenori Nagai
- Organizer
  The 11^<th> International Symposium on Dendritic Cells
- Place of Presentation
  ルガーノ(スイス)
- Year and Date
  2010-09-29
- Data Source
  KAKENHI-PROJECT-21790476
[Presentation] Establishment of a novel collagen-induced arthritis model by manipulating dendritic cells.2010
- Author(s)
  Nagai S, Katori R, Oyama M, Koyasu S.
- Organizer
  The 11^<th> International Symposium on Dendritic Cells.
- Place of Presentation
  Lugano, Switzerland.
- Year and Date
  2010-09-28
- Data Source
  KAKENHI-PROJECT-21790476
[Presentation] 細菌感染における宿主免疫応答2010
- Author(s)
  永井重徳
- Organizer
  第11回Pharmaco-Hematologyシンポジウム
- Place of Presentation
  日本薬学会館(東京)(招待講演)
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-21790476
[Presentation] Reoxygenation accelerates the differentiation of Th17 cells primed under hypoxia.2010
- Author(s)
  Ikejiri A, Nagai S, Koyasu S.
- Place of Presentation
  神戸国際会議場.兵庫
- Year and Date
  2010-08-23
- Data Source
  KAKENHI-PROJECT-21790476
[Presentation] Role of phosphoinositide 3-kinase on helper T cell differentiation in Helicobacter pylori-induced gastritis.2010
- Author(s)
  Nagai S, Kurebayashi Y, Baba Y, Koyasu S.
- Organizer
  14^<th> International Congress of Immunology.
- Place of Presentation
  神戸国際会議場.兵庫
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-21790476
[Presentation] Regulation of Th17 cell differentiation by PI3K-Akt-mTORC1 axis.2010
- Author(s)
  Kurebayashi Y, Nagai S, Baba Y, Koyasu S.
- Organizer
  14^<th> International Congress of Immunology.
- Place of Presentation
  神戸国際会議場.兵庫
- Year and Date
  2010-08-23
- Data Source
  KAKENHI-PROJECT-21790476
[Presentation] 細菌感染における宿主免疫応答2010
- Author(s)
  永井重徳、小安重夫
- Organizer
  第11回Pharmaco-Hematologyシンポジウム
- Place of Presentation
  日本薬学会館(東京).東京
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-21790476
[Presentation] 生体内で優れた抗菌活性を有するインプラントの開発2010
- Author(s)
  船尾陽生, 石井賢, 永井重徳, 佐々木あや, 干川智之, 相澤守, 岡田保典, 千葉一裕, 小安重夫, 戸山芳昭, 松本守雄
- Organizer
  第25回日本整形外科学会基礎学術集会
- Place of Presentation
  京都国際会館.京都
- Year and Date
  2010-10-14
- Data Source
  KAKENHI-PROJECT-21790476
[Presentation] In vivo imagingを用いた定量的マウス慢性骨髄炎モデルの確立2010
- Author(s)
  船尾陽生, 石井賢, 永井重徳, 佐々木あや, 干川智之, 相澤守, 岡田保典, 千葉一裕, 小安重夫, 戸山芳昭, 松本守雄
- Organizer
  第25回日本整形外科学会基礎学術集会
- Place of Presentation
  京都国際会館.京都
- Year and Date
  2010-10-14
- Data Source
  KAKENHI-PROJECT-21790476
[Presentation] Establishment of a novel collagen-induced arthritis model by manipulating dendritic cells.2010
- Author(s)
  Katori R, Oyama M, Nagai S, Koyasu S.
- Place of Presentation
  神戸国際会議場.兵庫
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-21790476
[Presentation] Role of phosphoinositide 3-kinase on helper T cell differentiation in Helicobacter pylori-induced gastritis.2010
- Author(s)
  Shigenori Nagai
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  神戸国際会議場(兵庫)
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-21790476
[Presentation] Establishment of Quantitative Model of Staphylococcal Osteomyelitis Using Bioimaging Techniques.2009
- Author(s)
  Funao H, Ishii K, Nagai S, Sasaki A, Hoshikawa T, Aizawa M, Okada Y, Chiba K, Koyasu S, Toyama Y, Matsumoto M.
- Organizer
  The 9^<th> World Congress on Inflammation.
- Place of Presentation
  京王プラザホテル.東京
- Year and Date
  2009-07-08
- Data Source
  KAKENHI-PROJECT-21790476
[Presentation] Immune regulation by Th17 cells of the induction of Helicobacter pylori-induced gastritis.2009
- Author(s)
  永井重徳
- Organizer
  第82回日本細菌学会総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2009-03-13
- Data Source
  KAKENHI-PROJECT-19790364
[Presentation] Critical roles of NK and CD8^+ T cells in central nervous system listeriosis.2009
- Author(s)
  Hayashi T, Nagai S, Fujii H, Baba Y, Ikeda E, Kawase T, Koyasu S.
- Organizer
  The 17^<th> International Symposium of Macrophage Molecular and Cell Biology 2009.
- Place of Presentation
  KKRホテル金沢.石川
- Year and Date
  2009-07-03
- Data Source
  KAKENHI-PROJECT-21790476
[Presentation] Immune regulation by Th17 cells of the induction of Helicobacter pyiori-induced gastritis2009
- Author(s)
  永井重徳, ほか
- Organizer
  第82回日本細菌学会総会
- Place of Presentation
  愛知
- Year and Date
  2009-03-13
- Data Source
  KAKENHI-PROJECT-20060021
[Presentation] The role of helper T cells in Helicobacter pylori-induced gastritis.2009
- Author(s)
  Nagai S.
- Organizer
  GI Executive Meeting 2009.
- Place of Presentation
  京都ブライトンホテル.京都
- Year and Date
  2009-06-19
- Data Source
  KAKENHI-PROJECT-21790476
[Presentation] The role of helper T cells in Helicobacter pylori-induced gastritis.2009
- Author(s)
  Shigenori Nagai
- Organizer
  GI Executive Meeting 2009
- Place of Presentation
  京都
- Year and Date
  2009-06-19
- Data Source
  KAKENHI-PROJECT-20060021
[Presentation] Role of PI3K-mTOR pathway in Th17 cell differentiation.2009
- Author(s)
  Kurebayashi Y, Nagai S, Baba Y, Koyasu S.
- Organizer
  The 9^<th> World Congress on Inflammation.
- Place of Presentation
  京王プラザホテル.東京
- Year and Date
  2009-07-08
- Data Source
  KAKENHI-PROJECT-21790476
[Presentation] The role of helper T cells in Helicobacter pylori-induced gastritis.2009
- Author(s)
  Shigenori Nagai
- Organizer
  GI Executive Meeting 2009
- Place of Presentation
  京都
- Year and Date
  2009-06-19
- Data Source
  KAKENHI-PROJECT-21790476
[Presentation] Immune regulation by Th17 cells of the induction of Helicobacter pyioriinduced gastritis2009
- Author(s)
  永井重徳, ほか
- Organizer
  第82回日本細菌学会総会
- Place of Presentation
  愛知
- Year and Date
  2009-03-13
- Data Source
  KAKENHI-PROJECT-19790364
[Presentation] Regulation of Th17 cell differentiation by PI3K-Akt-mTORC1 axis.2009
- Author(s)
  Kurebayashi Y, Nagai S, Baba Y, Koyasu S.
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸国際会議場.兵庫
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-21790476
[Presentation] Role of IL-17A in Heliocbacter pylori-induced gastritis.2009
- Author(s)
  Nagai S, Kurebayashi Y, Baba Y, Koyasu S.
- Organizer
  The 9^<th> World Congress on Inflammation.
- Place of Presentation
  京王プラザホテル.東京
- Year and Date
  2009-07-08
- Data Source
  KAKENHI-PROJECT-21790476
[Presentation] Role of PI3K on the production of cytokines by plasmacytoid dendritic cells2008
- Author(s)
  永井重徳
- Organizer
  The 10th International Symposium on Dendritic Cells
- Place of Presentation
  神戸国際会議場
- Year and Date
  2008-10-02
- Data Source
  KAKENHI-PROJECT-19790364
[Presentation] Helicobacter pylori感染による胃炎発症におけるTh17細胞の役割2008
- Author(s)
  永井重徳
- Organizer
  第6回沖縄感染症フォーラム
- Place of Presentation
  沖縄国民年金健康センター・サンセット美浜
- Year and Date
  2008-02-13
- Data Source
  KAKENHI-PROJECT-19790364
[Presentation] Role of IL-17A in Helicobacter pylori-induced gastritis2008
- Author(s)
  永井重徳, ほか
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Year and Date
  2008-12-01
- Data Source
  KAKENHI-PROJECT-19790364
[Presentation] Role of IL-17A in Helicobacter pylori-induced gastritis2008
- Author(s)
  永井重徳, ほか
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Year and Date
  2008-12-01
- Data Source
  KAKENHI-PROJECT-20060021
[Presentation] Role of IL-17A in the induction of Helicobacter pylori-induced gastritis2008
- Author(s)
  永井重徳
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  日京都国際会館
- Year and Date
  2008-12-01
- Data Source
  KAKENHI-PROJECT-19790364
[Presentation] Role of phosphoinositide 3-kinase on type I interferon production by plasmacytoid dendritic cells2008
- Author(s)
  Shigenori Nagai, et.al.
- Organizer
  The 10^<th> International Symposium on Dendritic Cells
- Place of Presentation
  兵庫
- Year and Date
  2008-10-03
- Data Source
  KAKENHI-PROJECT-20060021
[Presentation] Role of phosphoinositide 3kinase on type I interferon production by plasmacytoid dendritic cells2008
- Author(s)
  Shigenori Nagai, et.al.
- Organizer
  The 10^<th> International Symposium on Dendritic Cells
- Place of Presentation
  兵庫
- Year and Date
  2008-10-03
- Data Source
  KAKENHI-PROJECT-19790364
[Presentation] 胃炎発症における球状ヘリコバクターピロリの重要性2007
- Author(s)
  永井重徳
- Organizer
  第13回日本ヘリコバクター学会
- Place of Presentation
  滋賀県大津市
- Year and Date
  2007-06-22
- Data Source
  KAKENHI-PROJECT-19790364
[Presentation] 胃炎発症における球状ヘリコバクターピロリの重要性2007
- Author(s)
  永井重徳
- Organizer
  第13回日本ヘリコバクター学会
- Place of Presentation
  琵琶湖ホテル
- Year and Date
  2007-06-22
- Data Source
  KAKENHI-PROJECT-19790364
[Presentation] 胃炎発症における球状ヘリコバグターピロリの重要性2007
- Author(s)
  永井重徳, 他
- Organizer
  第13回日本ヘリコバクター学会
- Place of Presentation
  滋賀
- Year and Date
  2007-06-22
- Data Source
  KAKENHI-PROJECT-18659141
[Presentation] The effects of carbonated hydroxyapatite on macrophage behaviors
- Author(s)
  K. Igeta, A. Nagai, M. Aizawa, K. Yamashita
- Organizer
  26th Symposium and Annual Meeting of the International Society for Ceramics in Medicine (26 Bioceramics)
- Place of Presentation
  スペイン、バルセロナ
- Year and Date
  2014-11-06 – 2014-11-08
- Data Source
  KAKENHI-PROJECT-24500531
[Presentation] Cellular Responses of Immune Cells Derived from Mouse Spleen to Hydroxyapatite Ceramics Surface-modified with Inositol Phosphate.
- Author(s)
  Kiyotaka Yamada, Mariko Nakamura, Shigenori Nagai, Michiyo Honda, Mamoru Aizawa
- Organizer
  26th Symphosium and Annual Meeting of the International Society for Ceramics in Medicine
- Place of Presentation
  Barcelona, Italy.
- Year and Date
  2014-11-06 – 2014-11-08
- Data Source
  KAKENHI-PROJECT-26293400
[Presentation] Cellular responses of immune cells derived from mouse spleen to hydroxyapatite ceramics surface-modified with inositol phosphate
- Author(s)
  K. Yamada, M. Nakamura, S. Nagai, M. Honda, M. Aizawa
- Organizer
  26th Symposium and Annual Meeting of the International Society for Ceramics in Medicine (26 Bioceramics)
- Place of Presentation
  スペイン、バルセロナ
- Year and Date
  2014-11-06 – 2014-11-08
- Data Source
  KAKENHI-PROJECT-24500531
[Presentation] TGF-βによるAktおよびFoxoのリン酸化はiTreg分化を負に制御する
- Author(s)
  永井重徳，紅林泰，東みゆき，吉村昭彦，小安重夫．
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26293400
[Presentation] イノシトールリン酸を表面修飾した水酸アパタイトセラミックスに対するマウス脾臓由来免疫細胞の応答性．
- Author(s)
  山田清貴，中村まり子，永井重徳，本田みちよ，相澤守
- Organizer
  第24回無機リン化学討論会
- Place of Presentation
  高知
- Year and Date
  2014-09-25 – 2014-09-26
- Data Source
  KAKENHI-PROJECT-26293400
[Presentation] イノシトールリン酸を表面修飾した水酸アパタイトセラミックスに対するマウス脾臓由来免疫細胞の応答性
- Author(s)
  山田清貴・中村まり子・永井重徳・本田みちよ・相澤守
- Organizer
  第24回無機リン化学討論会
- Place of Presentation
  高知
- Year and Date
  2014-09-25 – 2014-09-26
- Data Source
  KAKENHI-PROJECT-24500531
[Presentation] 炭酸含有アパタイトの合成とマクロファージ接着に与える影響
- Author(s)
  井ヶ田一貴・永井亜希子・相澤守・山下仁大
- Organizer
  第24回無機リン化学討論会
- Place of Presentation
  高知
- Year and Date
  2014-09-25 – 2014-09-26
- Data Source
  KAKENHI-PROJECT-24500531
[Presentation] Phosphorylation of Akt and Foxos induced by TGF-β negatively controls the differentiation of Induced Regulatory T Cells.
- Author(s)
  Shigenori Nagai, Yutaka Kurebayashi, Miyuki Azuma, Akihiro Yoshimura, Shigeo Koyasu
- Organizer
  第43回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-26293400

1. AIZAWA Mamoru (10255713)

# of Collaborated Projects: 3 results

# of Collaborated Products: 34 results
2. Azuma Miyuki (90255654)

# of Collaborated Projects: 3 results

# of Collaborated Products: 36 results
3. ISEKI Sachiko (80251544)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. 大野建州 (80435635)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
5. 塗隆志 (40445995)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 上田晃一 (90257858)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. TOMURA Michio (30314321)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. YOSHIMURA Akihiko (90182815)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. OHTANI Masashi (20383713)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. WATANABE Toshio (60201208)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 小安重夫 (90153684)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 河野洋平 (20401383)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 武智正樹 (10455355)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
14. 足立礼孝 (10631533)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 由井伸彦 (70182665)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 有坂慶紀 (70590115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 吉本由紀 (40735304)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 青戸一司 (60360476)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 二宮洋一郎 (90237777)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. NOZAKI Kosuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. HORIUCHI Naohiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 平尾敦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 傅田香里

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 中浜健一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 田澤建人

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
26. 松田達志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 立浪秀剛

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
28. 地主将久

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 永井亜希子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nagai Shigenori 永井 重徳

NAGAI Shigenori 永井 重徳

永井 重徳 ナガイ シゲノリ

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Role of FoxO1 on Tr1 differentiationPrincipal Investigator

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Clarification of immunoregulatory mechanisms by crosstalk of immune cellsPrincipal Investigator

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Differentiation and function of Foxp3-negative IL-10-producing regulatory T cells on mucosal bacterial infectionPrincipal Investigator

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The role of PI3K-Akt-mTORC1 signaling pathway on Th17 differentiationPrincipal Investigator

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Role of Helper T cells on Helicobacter pylori-induced gastritis.Principal Investigator

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腸管免疫系の炎症誘発に関わるTh17細胞の機能・分化におけるPI3Kの役割Principal Investigator

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Nagai Shigenori 永井重徳

NAGAI Shigenori 永井重徳

永井重徳ナガイシゲノリ