OKAYASU Ryuichi 岡安隆一

… Alternative Names

RYUICHI Okayasu 岡安隆一

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Researcher Number	50356135
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2015: 国立研究開発法人放射線医学総合研究所, 放射線防護研究センター, 主任研究員 2014: 独立行政法人放射線医学総合研究所, 放射線防護研究センター, 主任研究員 2014: 放射線医学総合研究所, 放射線防護センターリスク低減化研究プログラム, 主任研究員 2014: 放射線医学総合研究所, 放射線防護研究センター, Senior Researcher 2013 – 2014: 独立行政法人放射線医学総合研究所, 放射線防護センターリスク低減化研究プログラム, 主任研究員 … More 2011 – 2013: 独立行政法人放射線医学総合研究所, 国際オープンラボラトリー, サイエンティフィックセクレタリー 2010: 放射線医学総合研究所, 重粒子医科学センター, グループリーダー 2007: National Institute of Radiological Sciences, Heavy-Ion Radiobiology Research Group, Group Leader 2006: 独立行政法人放射線医学総合研究所, 重粒子医科学センター・粒子線生物研究グループ, グループリーダー 2005: 独立行政法人放射線医学総合研究所, 宇宙放射線防護プロジェクト, プロジェクトリーダー 2004: 独立行政法人放射線医学総合研究所, 宇宙放射線防護プロジェクト, チームリーダー Less
Review Section/Research Field	Principal Investigator Radiation science Except Principal Investigator Radiation science / Clinical oncology / Living organism molecular science
Keywords	Principal Investigator 17AAG / Homologous recombination repair / Rad51 / siRNA / BRCA2 / DNA-PKcs / DNA DSB repair / Hsp90 inhibitor / Radio-sensitization / DNA ligase IV … More / RNA干渉 / 非相同末端結合 / 正常細胞 / 癌細胞 / アポトーシス / non-homologous end joining / 放射線抵抗性 / 17-AAG / DNA DSB修復 / 放射線増感材 / 相同組み換え修復 / DNA DSB 修復 / HSP90阻害剤 / 放射線増感剤 / マウスモデル / ヒートショック蛋白90阻害剤 / Ｘ線 / 相同組換修復 / Hsp90 阻害剤 / DNA損傷応答 / 併用療法 / Hsp90　阻害剤 / PU-H71 / 細胞老化 / 細胞周期 / DNA-PK阻害剤 / DNA二重鎖切断修復 / TAS-116 / 放射線増感 / 重粒子線 / Hsp90阻害剤 … More Except Principal Investigator 放射線 / 分子標的創薬 / ＲＮＡ / アプタマー / RNA / DNA損傷 / ＤＮＡ修復 / 画像工学 / ＲＮＡ工学 / 放射線生物影響 / がん / epigenetic / 合成致死 / アルキル化剤 / gamma irradiation / knockdown / DNMT3b / PARP1 / cancer / gamma-irradiation / NAD / PARG / PARP / 癌治療 / タンパク質リン酸化 / RNAアプタマー / 生理活性物質 / RNA工学 / DNA修復 / 放射線治療生物学 Less

Basic research to explore factors to improve effectiveness of radiation therapyPrincipal Investigator
- Principal Investigator
  
  OKAYASU RYUICHI
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Radiation science
- Research Institution
  National Institute of Radiological Sciences
Molecular targeted drug discovery for cancer cell radiosensitization using RNA technology
- Principal Investigator
  
  KURIMASA Akihiro
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Tottori University
Research for poly(ADP-ribosylation) as a potential cancer therapeutic target
- Principal Investigator
  
  MASUTANI MITSUKO
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Clinical oncology
- Research Institution
  National Cancer Center Japan
Molecular targeted drug discovery for cancer cell radiosensitization using RNA aptamars
- Principal Investigator
  
  KURIMASA Akihiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
- Research Field
  
  Living organism molecular science
- Research Institution
  Tottori University
Research for radio-sensitizers which specifically attack tumor cellsPrincipal Investigator
- Principal Investigator
  
  RYUICHI Okayasu
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Radiation science
- Research Institution
  National Institute of Radiological Sciences

All 2015 2014 2013 2012 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book

[Book] HIMAC20年の歩み: HIMAC20周年記念　研究成果要覧１セクション担当 (p27-34)2015
- Author(s)
  岡安隆一
- Total Pages
  245
- Publisher
  放射線医学総合研究所
- Data Source
  KAKENHI-PROJECT-24249067
[Book] Stress-Induced Mutagenesis2013
- Author(s)
  Allen, C. P., Fujimori, A., Okayasu, R., & Nickoloff, J. A.
- Publisher
  Springer New York
- Data Source
  KAKENHI-PROJECT-24249067
[Book] 癌の臨床(6月号の1章執筆)2007
- Author(s)
  岡安隆一、岡田真希、岡部篤史、野口実穂
- Publisher
  篠原出版新社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Book] 癌の臨床(6月号の一部を執筆)2007
- Author(s)
  岡安隆一、岡田真希、岡部篤史、野口実穂
- Total Pages
  60
- Publisher
  篠原出版新社
- Data Source
  KAKENHI-PROJECT-16209036
[Book] 放射線生物研究 41巻 (1章執筆)2006
- Author(s)
  岡安隆一
- Publisher
  放射線生物研究会
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Book] 日経サイエンス(1監訳+1自己原稿)2006
- Author(s)
  岡安隆一
- Publisher
  日経サイエンス(印刷中)(不明)
- Data Source
  KAKENHI-PROJECT-16209036
[Book] 放射線生物研究 40巻 (1章執筆)2005
- Author(s)
  岡安隆一、末冨勝敏、高橋千太郎
- Publisher
  放射線生物研究会
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] The complexity of DNA double strand break is a crucial factor for activating ATR signaling pathway for G2/M checkpoint regulation regardless of ATM function2015
- Author(s)
  Xue L, Furusawa Y, Okayasu R, Miura M, Cui X, Liu C, Hirayama R, Matsumoto Y, Yajima H, Yu D.
- Journal Title
  
  DNA Repair
  
  Volume: 25 Pages: 72-83
- DOI
  10.1016/j.dnarep.2014.11.004
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24249067, KAKENHI-PROJECT-25340042, KAKENHI-PROJECT-26293399, KAKENHI-PROJECT-15K09986
[Journal Article] DNA Damage Response Proteins and Oxygen Modulate Prostaglandin E2 Growth Factor Release in Response to Low and High LET Ionizing Radiation.2015
- Author(s)
  Allen CP, Tinganelli W, Sharma N, Nie J, Sicard C, Natale F, King M 3rd, Keysar SB, Jimeno A, Furusawa Y, Okayasu R, Fujimori A, Durante M, Nickoloff JA.
- Journal Title
  
  Frontiers in Oncology (Radiation Oncology)
  
  Volume: 5 Pages: 260-260
- DOI
  10.3389/fonc.2015.00260
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24249067
[Journal Article] VE-821, an ATR inhibitor, causes radiosensitization in human tumor cells irradiated with high LET radiation.2015
- Author(s)
  Fujisawa H, Nakajima NI, Sunada S, Lee Y, Hirakawa H, Yajima H, Fujimori A, Uesaka M, Okayasu R.
- Journal Title
  
  Radiation Oncology
  
  Volume: 10 Issue: 1 Pages: 175-175
- DOI
  10.1186/s13014-015-0464-y
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24249067
[Journal Article] A comprehensive analysis of radiosensitization targets; functional inhibition of DNA methyltransferase 3B radiosensitizes by disrupting DNA damage regulation.2015
- Author(s)
  Fujimori H, Sato A, Kikuhara S, Junhui W, Hirai T, Sasaki Y, Murakami Y, Okayasu R, Masutani M.
- Journal Title
  
  Sci Rep.
  
  Volume: on-line paper Issue: 1 Pages: 18231-18231
- DOI
  10.1038/srep18231
- NAID
  120006987240
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K06890, KAKENHI-PROJECT-26460310, KAKENHI-PROJECT-15K14416, KAKENHI-PROJECT-24249067
[Journal Article] The combination of Hsp90 inhibitor 17AAG and heavy-ion irradiation provides effective tumor control in human lung cancer cells.2015
- Author(s)
  Hirokazu Hirakawa, Hiroshi Fujisawa, Aya Masaoka, Miho Noguchi, Ryoichi Hirayama, Momoko Takahashi, Akira Fujimori, Ryuichi Okayasu
- Journal Title
  
  Cancer Medicine
  
  Volume: 4 Issue: 3 Pages: 426-436
- DOI
  10.1002/cam4.377
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-14J10543, KAKENHI-PROJECT-23390301, KAKENHI-PROJECT-24249067
[Journal Article] Novel characteristics of CtIP at damage-induced foci following the initiation of DNA end resection.2015
- Author(s)
  Hiroshi Fujisawa, Akira Fujimori, Ryuichi Okayasu, Mitsuru Uesaka, Hirohiko Yajima
- Journal Title
  
  Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
  
  Volume: 771 Pages: 36-44
- DOI
  10.1016/j.mrfmmm.2014.12.001
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-14J10543, KAKENHI-PROJECT-24249067, KAKENHI-PROJECT-25340042
[Journal Article] Heterochromatin domain number correlates with X-ray and carbon-ion radiation resistance in cancer cells2014
- Author(s)
  Sato K, Imai T, Okayasu R, Shimokawa T.
- Journal Title
  
  Radiat. Res.
  
  Volume: 182 Issue: 4 Pages: 408-419
- DOI
  10.1667/rr13492.1
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24249067, KAKENHI-PROJECT-24591857, KAKENHI-PROJECT-25861141
[Journal Article] Selective enhancing effect of Early mitotic inhibitor 1 depletion on sensi tivity of doxorubicin.2013
- Author(s)
  Shimizu N, Nakajima NI, Tsunematsu T, Ogawa I, Kawai H, Hirayama R, Fujimori A, Yamada A, Okayasu R, Ishimaru N, Takata T, Kudo Y.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 288 Issue: 24 Pages: 17238-17252
- DOI
  10.1074/jbc.m112.446351
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J06562, KAKENHI-PROJECT-23689074, KAKENHI-PROJECT-24249067, KAKENHI-PROJECT-24689068, KAKENHI-PROJECT-25340033, KAKENHI-PROJECT-25670798
[Journal Article] The complexity of DNA double strand breaks is a critical factor enhancing end-resection.2013
- Author(s)
  Yajima H1, Fujisawa H, Nakajima NI, Hirakawa H, Jeggo PA, Okayasu R, Fujimori A.
- Journal Title
  
  DNA Repair (Amst).
  
  Volume: 12(11) Pages: 936-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390301
[Journal Article] The complexity of DNA double strand breaks is a critical factor enhancing end-resection.2013
- Author(s)
  Yajima H, Fujisawa H, Nakajima NI, Hirakawa H, Jeggo P, Okayasu R, Fujimori A.
- Journal Title
  
  DNA Repair
  
  Volume: 12 Issue: 11 Pages: 936-946
- DOI
  10.1016/j.dnarep.2013.08.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249067, KAKENHI-PROJECT-25340042
[Journal Article] Parg deficiency confers radio-sensitization through enhanced cell death in mouse ES cells exposed to various forms of ionizing radiation.2013
- Author(s)
  Shirai H, Fujimori H, Gunji A, Maeda D, Hirai T, Poetsch AR, Harada H, Yoshida T, Sasai K, Okayasu R, Masutani M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 435(1) Pages: 100-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390301
[Journal Article] Selective enhancing effect of early mitotic inhibitor 1 (Emi1) depletion on the sensitivity of doxorubicin or X-ray treatment in human cancer cells.2013
- Author(s)
  Shimizu N, Nakajima NI, Tsunematsu T, Ogawa I, Kawai H, Hirayama R, Fujimori A, Yamada A, Okayasu R, Ishimaru N, Takata T, Kudo Y.
- Journal Title
  
  J Biol Chem.
  
  Volume: 288(24) Pages: 17238-52
- NAID
  120006718350
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390301
[Journal Article] Chromosome aberrations in normal human fibroblasts analyzed in G0/G1 and G2/M phases after exposure in G0 to radiation with different linear energy transfer (LET).2013
- Author(s)
  Liu C, Kawata T, et al
- Journal Title
  
  Mutat Res
  
  Volume: 756 Issue: 1-2 Pages: 101-107
- DOI
  10.1016/j.mrgentox.2013.05.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591849, KAKENHI-PROJECT-24249067, KAKENHI-PROJECT-24591859
[Journal Article] Visualisation of γH2AX foci caused by heavy ion particle traversal; distinction between core track versus non-track damage.2013
- Author(s)
  Nakajima NI, Brunton H, Watanabe R, Shrikhande A, Hirayama R, Matsufuji N, Fujimori A, Murakami T, Okayasu R, Jeggo P, Shibata A.
- Journal Title
  
  PLoS One.
  
  Volume: 8(8)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390301
[Journal Article] Parg Deficiency Confers Radio-sensitization through Enhanced Cell Death in Mouse ES Cells Exposed to Various Forms of Ionizing Radiation.2013
- Author(s)
  Shirai H, Fujimori H, Gunji A, Maeda D, Hirai T, Poetsch AR, Harada H, Yoshida T, Sasai K, Okayasu R, Masutani M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: Epub ahead of print Issue: 1 Pages: 100-106
- DOI
  10.1016/j.bbrc.2013.04.048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300343, KAKENHI-PROJECT-24249067, KAKENHI-PROJECT-24890233
[Journal Article] Visualisation of cH2AX Foci Caused by Heavy Ion Particle Traversal; Distinction between Core Track versus Non-Track Damage.2013
- Author(s)
  Nakajima NI, Brunton H, Watanabe R, Shrikhande A, Hirayama R, Matsufuji N, Fujimori A, Murakami T, Okayasu R, Jeggo P, Shibata A.
- Journal Title
  
  PLoS ONE
  
  Volume: 8 Issue: 8 Pages: e70107-e70107
- DOI
  10.1371/journal.pone.0070107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249067
[Journal Article] JS Comparison of the induction and disappearance of DNA double strand breaks and gamma-H2AX foci after irradiation of chromosomes in G1-phase or in condensed metaphase cell, Fundamental and Molecular Mechanisms of Mutagenesis.2008
- Author(s)
  Kato, T., ^*Okayasu, R., Bedford^*Bedford
- Journal Title
  
  Mutat. Res. 639
  
  Pages: 108-112
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] Comparison of the induction and disappearance of DNA double strand breaks and gamma-H2AX foci after irradiation of chromosome in G1-phase or in condensed metaphase cells2008
- Author(s)
  Takamitsu Kato, ^*Ryuichi Okayasu, ^*Joel S. Bedford
- Journal Title
  
  Mutation Research 639
  
  Pages: 108-112
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] Role of the major, small, acid-soluble spore proteins and spore-specific and universal DNA repair mechanisms in resistance of Bacillus subtilis spores to ioninzing radiation from X rays and high energy charged-particle bombardment.2008
- Author(s)
  Moeller, R., Stelow, P., Horneck, G., Berger, T., Reitz, G., Rettberg, P., Doherty, A. J., Okayasu, R., Nicholson, W. L.
- Journal Title
  
  J. Bacteriol. 190
  
  Pages: 1134-1140
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] Down regulation of BRCA2 causes radio-sensitization of human tumor cells in vitro and in vivo.2008
- Author(s)
  Yu, D., Sekine, E., Fujimori, A., Ochiya, T., ^*Okayasu, R.
- Journal Title
  
  Cancer Sci. 99(4)
  
  Pages: 810-815
- NAID
  10024005276
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] Ionizing radiation downregulates ASPM, a gene responsible for microcephaly in humans.2008
- Author(s)
  Fujimori, A, Bing, W., Suetomi, K., Sekine, E., Yu, D., Kato, T., Takahashi, S., Okayasu, R. et. Al
- Journal Title
  
  Biochem. Biophys. Res. Commun. 369
  
  Pages: 953-957
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] Role of the major, small,acid-soluble spore proteins and spore-specific and universal DNA repair mechanisms in resistance of Bacillus subtilis spores to ionizing radiation from X rays and high energy charged-particle bombardment2008
- Author(s)
  Ralf Moeller, Peter Setlow, Gerda Homeck, Thomas Berger, Gunther Reitz, Petra Rettberg, Aidan J.Doherty, Rynichi Okayasu, Wayne L Nicholson
- Journal Title
  
  Journal of Bacteriology 190
  
  Pages: 1134-1140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] High LET heavy ion radiation induces lower numbers of initial chromosome breaks with minimal repair than low LET radiation in normal human cells.2008
- Author(s)
  Sekine, E., Okada, M., Matsufuji, N., Yu, D., Furusawa, Y. ^*Okayasu, R.
- Journal Title
  
  Mutat. Res. 652
  
  Pages: 95-101
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] High LET heavy ion radiation induces lower numbers of initial chromosome breaks with minimal repair than low LET radiation in normal human cells2008
- Author(s)
  Eimiko Sekine, Maki Okada, Naruhiro Matsufuji, Dong Yu, Yoshiya Furusawa, *Ryuichi Okayasu
- Journal Title
  
  Mutation Research 652
  
  Pages: 95-101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] Comparison of the induction and disappearance of DNA double strand breaks and gamma-H2AX foci after irradiation of chromosome in G1-phase or in condensed metaphase cells2008
- Author(s)
  Takamitsu Kato, *Ryuichi Okayasu, *Joel S. Bedford
- Journal Title
  
  Mutation Research 639
  
  Pages: 108-112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] Ionizing radiation downregulates ASPM, a gene responsible for microcephaly in humans2008
- Author(s)
  Akira Fujimori, Wang Bing, Katsutoshi Suetomi, Eimiko Sekine, Dong Yu, Takamitsu Kato, Sentaro Takahashi, Ryuichi Okayasu, et. al.
- Journal Title
  
  Biochemical and Biophysical Research Communications 369
  
  Pages: 953-957
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] High LET heavy ion radiation induces lower numbers of initial chromosome breaks with minimal repair than low LET radiation in normal human cells2008
- Author(s)
  Eimiko Sekine, Maki Okada, Naruhiro Matsufuji, Dong Yu, Yoshiya Furusawa, ^*Ryuichi Okayasu
- Journal Title
  
  Mutation Research 652
  
  Pages: 95-101
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] Down regulation of BRCA2 causes radio-sensitization of human tumor cells2008
- Author(s)
  Dong Yu, Eimiko Sekine, Akira, Fujimori, Takahiro Ochiya,* Ryuichi Okayasu:
- Journal Title
  
  Cancer Science 99
  
  Pages: 810-815
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] Role of the major, small, acid-soluble spore proteins and spore-specific and universal DNA repair mechanisms in resistance of Bacillus subtilis spores to ionizing radiation from X rays and high energy charged-particle bombardment2008
- Author(s)
  Ralf Moeller, Peter Setlow, Gerda Horneck, Thomas Berger, Gunther Reitz, Petra Rettberg, Aidan J. Doherty, Ryuichi Okayasu, Wayne L Nicholson
- Journal Title
  
  Journal of Bacteriology 190
  
  Pages: 1134-1140
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] Down regulation of BRCA2 causes radio-sensitization of human tumor cells2008
- Author(s)
  Dong Yu, Eimiko Sekine, Akira, Fujimori, Takahiro Ochiya, ^*Ryuichi Okayasu :
- Journal Title
  
  Cancer Science 99
  
  Pages: 810-815
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] Cytotoxicity of cigarette smoke condensate is not due to DNA double strand breaks: Comparative studies using radiosensitive mutant and wild-type CHO cells2007
- Author(s)
  Takamitsu Kato, Hatsumi Nagasawa, Christy Wamer,* Ryuichi Okayasu,*Joel S.Bedfbrd
- Journal Title
  
  Intemational Journal of Radiation Biology 83
  
  Pages: 583-591
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] DNA topoisomerase inhibitor, etoposide, enhances GC-box-dependent promoter activity via Spl phosphorylation.2007
- Author(s)
  Niina I, Uchiumi T, Izumi H, torigoe T, Wakasugi T, Igarashi T, Miyamoto N, Onitsuka T, Shiota M, Okayasu R, Chijiiwa K, Kohno K.
- Journal Title
  
  Cancer Sci. 98
  
  Pages: 858-863
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] Single extreme low dose/low dose rate irradiation causes alteration in lifespan and genome instability in primary human cells.2007
- Author(s)
  Okada M, Okabe A, Uchihori Y, Kitamura H, Sekine E, Ebisawa S, Suzuki M, Okayasu R.
- Journal Title
  
  British Journal of Cancer 96
  
  Pages: 1707-1710
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] CELLULAR SIGNAL TRANSDUCTION EVENTS AS A FUNCTION OF LINEAR ENERGY TRANSFER(LET).2007
- Author(s)
  Furweger C., Hajek, M., Vana, N., Kodym, R., Okayasu, R.
- Journal Title
  
  Radiat. Protec. Dosimetry
  
  Pages: 1-5
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] CELLULAR SIGNAL TRANSDUCTION EVENTS AS A FUNCTION OF LINEAR ENERGY TRANSFER(LET)2007
- Author(s)
  Furweger Christoph, Michael Hajek, Norbert Vana, R Kodym, Ryuichi Okayasu
- Journal Title
  
  Radiation Protection Dosimetry 126
  
  Pages: 418-422
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] ENHANCEMENT OF CHROMOSOMAL ABERRATIONS INTUMOR CELLS WITH A NON-LABELED CU-PTSM ANDIRRADIATION WITH CU-K SHELL MONOCHROMATIC X RAYS.2007
- Author(s)
  Takakura, K., Yaguchi, S., Kanasugi, Y., Kobayashi, K., Okayasu, R., Fujibayashi, Y.
- Journal Title
  
  Radiat. Protec. Dosimetry 122
  
  Pages: 188-194
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] Single extreme low dose/low dose rate irradiation causes alteration in lifespan and genome instability in primary human cells.2007
- Author(s)
  Okada M, Okabe A, Uchihori Y, Kitamura H, Sekine E, Ebisawa S, Suzuki M, Okayasu R.
- Journal Title
  
  Br J Cancer (印刷中)
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] JS Cytotoxicity of cigarette smoke condensate is not due to DNA double strand breaks : Comparative studies using radiosensitive mutant and wild-type CHO cells2007
- Author(s)
  Kato, T., Nagasawa, H., Warner, C., ^*Okayasu R., Bedford^*
- Journal Title
  
  Int. J. Radiat. Biol. 83
  
  Pages: 583-591
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] Single extreme low dose/low dose rate irradiation causes alteration in life span and genome instability in primary human cells.2007
- Author(s)
  Okada, M., Okabe, A., Uchihori, Y., Kitamura, H., Sekine, E., Ebisawa, S., Suzuki, M., ^*Okayasu R.
- Journal Title
  
  Br. J. Cancer 96
  
  Pages: 1707-1710
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] DNA topoisomerase inhibitor, etoposide, enhances GC-box-dependent promoter activity via Sp1 phosphorylation.2007
- Author(s)
  Niina I, Uchiumi T, Izumi H, Torigoe T, Wakasugi T, Igarashi T, Miyamoto N, Onitsuka T, Shiota M, Okayasu R, Chijiiwa K, Kohno K.
- Journal Title
  
  Cancer Science 98
  
  Pages: 858-863
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] DNA topoisomerase inhibitor, etoposide, enhances GC-box-dependent promoter activity via Sp1 phosphorylation.2007
- Author(s)
  Niina I, Uchiumi T, Izumi H, Torigoe T, Wakasugi T, Igarashi T, Miyamoto N, Onitsuka T, Shiota M, Okayasu R, Chijiiwa K, Kohno K.
- Journal Title
  
  Cancer Sci. (印刷中)
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] Enhancement of chromosomal aberrations in tumor cells with a non-labeled Cu-PTSM and irradiation with Cu K-shell monochromatic X rays.2007
- Author(s)
  Takakura K, Yaguchi S, Kanansugi Y, Kobayashi K, Okayasu R, Fujibayashi Y.
- Journal Title
  
  Radiation Protection Dosimetry 122
  
  Pages: 188-194
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] Enhancement of chromosomal aberrations in tumor cells with a non-labeled Cu-PTSM and irradiation with Cu K-shell monochromatic X rays.2007
- Author(s)
  Takakura K, Yaguchi S, Kanansugi Y, Kobayashi K, Okayasu R, Fujibayashi Y.
- Journal Title
  
  Radiat Prot Dosimetry. (印刷中)
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] Cytotoxicity of cigarette smoke condensate is not due to DNA double strand breaks : Comparative studies using radiosensitive mutant and wild-type CHO cells2007
- Author(s)
  Takamitsu Kato, Hatsumi Nagasawa, Christy Warner, ^*Ryuichi Okayasu, Joel S. Bedford
- Journal Title
  
  International Journal of Radiation Biology 83
  
  Pages: 583-591
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] Inhibition of homologous recombination repair in irradiated tumor cells pretreated with Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin.2006
- Author(s)
  Noguchi M, Yu D, Hirayama R, Ninomiya Y, Sekine E, Kubota N, Ando K, Okayasu R.
- Journal Title
  
  Biochemistry Biophysics Research Communications 351
  
  Pages: 658-663
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] 高LET放射線と非相同末端結合修復2006
- Author(s)
  岡安隆一
- Journal Title
  
  放射線生物研究 41
  
  Pages: 424-432
- NAID
  40015265468
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] The PCC assay can be used to predict radiosensitivity in biopsy cultures irradiated with different types of radiation.2006
- Author(s)
  Suzuki M, Tsuruoka C, Nakano T, Ohno T, Furusawa Y, Okayasu R.
- Journal Title
  
  Oncology Report 18
  
  Pages: 1293-1299
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] Inhibition of homologous recombination repair in irradiated tumor cells pretreated with Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin.2006
- Author(s)
  Noguchi M, Yu D, Hirayama R, Ninomiya Y, Sekine E, Kubota N, Ando K, Okayasu R.
- Journal Title
  
  Biochem Biophys Res Commun 351
  
  Pages: 658-663
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] The PCC assay can be used to predict radiosensitivity in biopsy cultures irradiated with different types of radiation.2006
- Author(s)
  Suzuki M, Tsuruoka C, Nakano T, Ohno T, Furusawa Y, Okayasu R.
- Journal Title
  
  Oncol Rep. 16
  
  Pages: 1293-1299
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] Inhibition of Homologous Recombination Repair in Irradiated Tumor Cells Pretreated with Hsp90 Inhibitor 17-Allylamino-17-demethoxygeldanamycin.2006
- Author(s)
  Noguchi, M, Yu, D., Hirayama, R., Ninomiya, Y., Sekine, E., Kubota, N., Ando, K. Okayasu, R.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 351
  
  Pages: 658-663
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] The PCC assay can be used to predict radiosensitivity in biopsy cultures irradiated with different types of radiation.2006
- Author(s)
  Suzuki, M., Tsuruoka, C., Nakano, T., Ohno, Y., Furusawa, Okayasu, R.
- Journal Title
  
  Oncol. Rep. 16
  
  Pages: 1293-1299
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] Heavy ion radiation induces complex DNA damage that cannot be efficiently repaired by non-homologous end joining.2006
- Author(s)
  Okayasu, R., Okada, M, Okabe, A., Noguchi, M., Takakara, K., takahashi, S.
- Journal Title
  
  Radiat. Res. 165
  
  Pages: 59-67
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] Repair of DNA damage induced by accelerated heavy ions in mammalian cells proficient and deficient in the Non-homologous End-joining pathway2006
- Author(s)
  Ryuichi Okayasu, Maki Okada, Atsushi Okabe, Miho Noguchi, Kaoru Takakura, Sentaro Takahashi
- Journal Title
  
  Radiation Research 165
  
  Pages: 59-67
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] Radio-sensitivity of the cells from amyotrophic lateral sclerosis model mice transfected with human mutant SOD1.2005
- Author(s)
  Iimuro, R, Takahashi, S, Ito, H, Kubota, Y, Suetomi, K, Sato, H, Okayasu, R.
- Journal Title
  
  Journal of Radiation Research 46
  
  Pages: 67-73
- NAID
  110004041097
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] Radio-sensitivity of the cells from amyotrophic lateral sclerosis model mice transfected with human mutant SOD12005
- Author(s)
  Iimuro, R, Takahashi, S, Ito, H, Kubota, Y, Suetomi, K, Sato, H, Okayasu, R.
- Journal Title
  
  J. Radiat. Res. 46
  
  Pages: 67-73
- NAID
  110004041097
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] Caffeine sensitizes non-dividing human fibroblasts to X-rays by inducing high frequency of misrepair.2005
- Author(s)
  Kawata, T., Ito, H., Saito, M., Uno, T., Okayasu, R, et. al.
- Journal Title
  
  Radiation Research 164
  
  Pages: 509-513
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] Caffeine sensitizes non-dividing human fibroblasts to X-rays by inducing high frequency of misrepair2005
- Author(s)
  Tetsuya Kawata, Hisao Ito, Masayoshi Saito, Taskashi Uno, Ryuichi Okayasu, et al.
- Journal Title
  
  Radiation Research 164
  
  Pages: 509-513
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] Caffeine sensitizes non-dividing human fibroblasts to X-rays by inducing high frequency of misrepair.2005
- Author(s)
  Kawata, T., Ito, H., Saito, M., Uno, T., Okayasu, R., Liu, C., Kan'o, M., George, K., Cucinotta, F. A.
- Journal Title
  
  Radiat. Res. 164
  
  Pages: 509-513
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] Extremely Low-Dose Ionizing Radiation Upregulates CXC Chemokines in Normal Human Fibroblasts2005
- Author(s)
  Akira Fujimori, Ryuichi Okayasu, Hiroshi Ishihara, Satoshi Yoshida, Kiyomi Eguchi-Kasai, Kumie Nojima, Satoru Ebisawa, Sentaro Takahashi
- Journal Title
  
  Cancer Research 65
  
  Pages: 10159-10163
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] RNAi技法によるDNA二重鎖切断修復抑制:放射線治療への応用は可能か2005
- Author(s)
  岡安隆一, 末冨勝敏, 高橋千太郎
- Journal Title
  
  放射線生物研究 40
  
  Pages: 260-269
- NAID
  40006931641
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] Extremely low-dose ionizing radiation upregulates CXC chemokines in normal human fibroblasts.2005
- Author(s)
  Fujjimori, A., Okayasu, R., Ishihara, H., Yoshida, S., Eguchi-Kasai, K., Nojima, K., Ebisawa, S., takahashi, S.
- Journal Title
  
  Cancer Res. 65
  
  Pages: 10159-10163
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] Facilitated detection of chromosome break and repair at low levels of ionizing radiation by addition of wortmannin to G1-type PCC fusion incubation.2004
- Author(s)
  Okada M, Saito S, ^*Okayasu R
- Journal Title
  
  Mutat Res. 562
  
  Pages: 11-7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] Facilitated detection of chromosome break and repair at low levels of ionizing radiation by addition of wortmannin to G1-type PCC2004
- Author(s)
  Okada, M., S.Saito, Okayasu, R.
- Journal Title
  
  Mutation Research 562
  
  Pages: 11-17
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] Facilitated detection of chromosome break and repair at low levels of ionizing radiation by addition of wortmannin to G1-type PCC.2004
- Author(s)
  Okada, M., S. Saito, Okayasu, R.
- Journal Title
  
  Mutation Research 562
  
  Pages: 11-17
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16209036
[Journal Article] Effectiveness of combined treatment using X-rays and a phosphoinositide 3-kinase inhibitor, ZSTK474, on proliferation of HeLa cells in vitro and in vivo.
- Author(s)
  Anzai K, Sekine-Suzuki E, Ueno M, Okamura M, Yoshimi H, Dan S, Yaguchi SI, Enami J, Yamori T, Okayasu R
- Journal Title
  
  Caneer Sei. in press
- NAID
  10029294463
- Data Source
  KAKENHI-PROJECT-20200039
[Presentation] Radiosensitization effect of Hsp90 inhibitor CAY10607 in human tumor cells2015
- Author(s)
  Ryuichi Okayasu, Younghyun Lee, Aya Masaoka, Shigeaki Sunada
- Organizer
  日本癌学会　学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-24249067
[Presentation] EFFECTS OF HSP90 INHIBITOR PUH71 IN HEAVY ION IRRADIATED HUMAN CANCER CELLS2015
- Author(s)
  Lee Younghyun, Ryuichi Okayasu, Aya Masaoka, Huizi Li, Shigeaki Sunada
- Organizer
  放射線ワークショップ（第1回）-未来に繋ぐ放射線研究- 日本放射線影響学会
- Place of Presentation
  富山
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-24249067
[Presentation] DNA Methylation Alterations in Human Lymphocyte Induced by Gamma Radiation in Vitro2015
- Author(s)
  Lee Younghyun, Ryuichi Okayasu
- Organizer
  15th International Congress of Radiation Research
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2015-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24249067
[Presentation] Radiobiology Update for Radiation Oncologist2015
- Author(s)
  Ryuichi Okayasu
- Organizer
  15th International Congress of Radiation Research
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2015-05-25
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24249067
[Presentation] Hsp90阻害剤と重粒子線照射併用処理によるがん細胞の反応2013
- Author(s)
  正岡　綾, 平川　博一, 李　惠子, 岡安　隆一
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24249067
[Presentation] Biological radiosensitization by PARP inhibitors2013
- Author(s)
  Mitsuko Masutani, Takahisa Hirai, Hiroaki Fujimori, Souichiro Saito, Teiji Nishio, Ryuichi Okayasu, Akira Fujimori, Keisuke Sasai
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  神奈川県　横浜市　パシフィコ横浜
- Invited
- Data Source
  KAKENHI-PROJECT-22300343
[Presentation] Hsp90阻害剤PU-H71と炭素線照射の併用による癌抑制効果2013
- Author(s)
  岡安　隆一, 正岡　綾, 李　惠子, 平川　博一, 松本　孔貴, 藤森　亮
- Organizer
  日本癌学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24249067
[Presentation] Biological basis for heavy ion radiotherapy2013
- Author(s)
  Ryuichi Okayasu
- Organizer
  International Symposium on Radiation Sciences
- Place of Presentation
  Taipei, Taiwan
- Invited
- Data Source
  KAKENHI-PROJECT-24249067
[Presentation] Hsp90 inhibitor is a good candidate for effective combination therapy with carbon ions2013
- Author(s)
  Ryuichi Okayasu, Hirokazu Hirakawa, Aya Masaoka, Miho Noguchi, Ryoichi Hirayama, Huizi Li, Yoshitaka Matsumoto, Akira Fujimori
- Organizer
  HITSRS 2013
- Place of Presentation
  Chiba, Japan
- Data Source
  KAKENHI-PROJECT-24249067
[Presentation] Hsp90 inhibitor may enhance the effectiveness of heavy ion treatment2012
- Author(s)
  Ryuichi Okayasu
- Organizer
  Radiation Research Society 58th Annual Meeting
- Place of Presentation
  プエルトリコ, San　Juan
- Data Source
  KAKENHI-PROJECT-24249067
[Presentation] Radio-sensitization by Parg deficiency in mouse ES cells exposed to low and high LET radiation.2012
- Author(s)
  Hidenori Shirai, Takahisa Hirai, Keisuke Sasai2 Ryuichi Okayasu, Mitsuko Masutani
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-22300343
[Presentation] Significant tumor radio-sensitization by the combined treatment of hsp90 inhibitor and heavy ion irradiation in vivo2012
- Author(s)
  Ryuichi Okayasu
- Organizer
  第7１回日本癌学会学術総会
- Place of Presentation
  札幌芸文館（北海道）
- Data Source
  KAKENHI-PROJECT-24249067
[Presentation] Radiobiology for Heavy-Ion Radiotherapy2008
- Author(s)
  Okayasu, R., Kato, T., Noguchi, M., Okada, M., Fujimori, A., Sekine, E.
- Organizer
  NIRS-MD Anderson Symposium on Clinical Issues for Particle Therapy
- Place of Presentation
  Houston, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Presentation] Radiobiology for Heavy-Ion Radiotherapy,2008
- Author(s)
  Okayasu, R., Kato, T., Noguchi, M., Okada, M., Fujimori, A., Sekine, E.
- Organizer
  NIRS-MD Anderson Symposium on Clinical Issues for Particle Therapy
- Place of Presentation
  Houston,
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Presentation] Radiobiology for Heavy-Ion Radiotherapy2008
- Author(s)
  Okayasu, R.
- Organizer
  NIRS-MD Anderson Symposium on Clinical Issues for Particle Therapy
- Place of Presentation
  Houston,USA
- Year and Date
  2008-03-22
- Data Source
  KAKENHI-PROJECT-16209036
[Presentation] BRCA2 siRNAを用いたin vitro, in vivoでの放射線増感2008
- Author(s)
  岡安隆一、干冬、関根絵美子、落谷孝広、藤森亮
- Organizer
  第10回癌治療増感研究シンポジウム
- Place of Presentation
  奈良
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Presentation] BRCA2 siRNAを用いたin vitro,in vivoでの放射線増感2008
- Author(s)
  岡安隆一
- Organizer
  第10回癌治療増感研究シンポジウム
- Place of Presentation
  奈良市
- Year and Date
  2008-02-10
- Data Source
  KAKENHI-PROJECT-16209036
[Presentation] Down regulation of BRCA2 enhances tumor radio-sensitivity throughinhibition of homologous recombination repair2007
- Author(s)
  Okayasu, R.
- Organizer
  アメリカ癌学会
- Place of Presentation
  Los Angels,USA
- Year and Date
  2007-04-17
- Data Source
  KAKENHI-PROJECT-16209036
[Presentation] 極低線量・低線量率重粒子線1回照射による細胞老化およびゲノム不安定性2007
- Author(s)
  岡安隆一、岡田真希、岡部篤史、関根絵美子、内堀幸夫、北村尚、鈴木雅雄
- Organizer
  日本放射線影響学会第50回大会
- Place of Presentation
  千葉市
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Presentation] Comparison of phosphorylation kinetics in DNA repair proteins after exposure to high and low LET radiations.2006
- Author(s)
  Okayasu, R., Okabe, A., Takakura, K
- Organizer
  The 36th COSPAR Scientific Assembly
- Place of Presentation
  Beijing, China
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Presentation] ATM protein plays a critical role in repairing the complex DNA double strand breaks induced by high LET radiation.2006
- Author(s)
  Okayasu, R., Okabe, A., Takakura, K.
- Organizer
  Radiation Research Society 53rd Annual Meeting
- Place of Presentation
  Philadelphia, PA USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Presentation] Application of HiCEP, a novel method which can detect known and unknown gene expression changes after exposure to low dose X-rays.2006
- Author(s)
  Okayasu, R., Fujimori, A., Takahashi, S.
- Organizer
  The sixth Japan-France workshop on radiobiology and isotopic imaging
- Place of Presentation
  Paris, France
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Presentation] Application of HiCEP, a novel method which can deteck known and unknown gene expression changes after exposure to low dse X-rays,2006
- Author(s)
  Okayasu, R., Fujimori, A., Takahashi, S.
- Organizer
  The sixth Japan-France workshop on radiobiology and isotopic imaging,
- Place of Presentation
  Paris, France
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Presentation] Comparison of phosphorylation kinetics in DNA repair proteins after exposure to high and low LET radiations,2006
- Author(s)
  Okayasu, R., Okabe, A., Takakura, K
- Organizer
  The 36th COSPAR Scientific Assembly,
- Place of Presentation
  北京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Presentation] ATM protein plays a critical role in repairing the complex DNA double strand breaks induces by high LET radiation,2006
- Author(s)
  Okayasu, R., Okabe, A., Takakura, K.
- Organizer
  Radiation Research Society 53rd Annual Meeting,
- Place of Presentation
  Philadelphia, PA
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Presentation] High LET radiation affects non-homologous end joining repair in human cells.2005
- Author(s)
  Okayasu, R., Okada, M, Okabe, A., Takahashi, S.
- Organizer
  96th Annual Meeting, Anaheim
- Place of Presentation
  CA, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Presentation] High Let radiation uncovers a new aspect of DNA double strand break repair.2005
- Author(s)
  Okayasu, R., Okada, M., Okabe, A., Noguchi, M., Takahashi, S.
- Organizer
  Japan Radiation Research Society Annual Meeting and The 1st Asian Radiation Research Conference
- Place of Presentation
  Hiroshima, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Presentation] High LET radiation affects non-homologous end joining repair in human cells.2005
- Author(s)
  Okayasu, R., Okada, M., Okabe, A., Takahashi, S.
- Organizer
  96th Annual Meeting.
- Place of Presentation
  Anaheim, CA
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Presentation] Extreme low dose rate irradiation with heavy ions induces accelerated senescence in primary human cells.2005
- Author(s)
  Okayasu, R., Okada, M., Okabe, A., Uchihori, Y., Suzuki, M., Takahashi, S.
- Organizer
  The 52nd Radiation Research Society Annual Meeting,
- Place of Presentation
  Denver,
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Presentation] Extreme low dose rate irradiation with heavy ions induces accelerated senescence in primary human cells.2005
- Author(s)
  Okayasu, R., Okada, M., Okabe, A., Uchihori, Y., Suzuki, M., Takahashi, S.
- Organizer
  The 52nd Radiation Research Society Annual Meeting
- Place of Presentation
  Denve, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Presentation] High LET radiation uncovers a new aspect of DNA double strand break repair.2005
- Author(s)
  Okayasu, R., Okada, M., Okabe, A., Noguchi, M., Takahashi, S.
- Organizer
  Japan Radiation Research Society Annual Meeting and The 1st Asian Radiation Research Conference
- Place of Presentation
  Hiroshima, Japan,
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Presentation] Characteristic studies of non homologous end joining in human cells irradiated with high LET radiation.2004
- Author(s)
  Okayasu, R., Okada, M., Okabe, A. and Takakura, K
- Organizer
  35th COSPAR Scientific Assembly
- Place of Presentation
  Paris, France
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16209036
[Presentation] Investigation of a new Hsp90 inhibitor as combined with low and high LET radiation
- Author(s)
  正岡　綾、砂田成章、平川博一、根井　充、藤森　亮、岡安　隆一
- Organizer
  日本癌学会
- Place of Presentation
  パシフィコ　横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24249067
[Presentation] Effectiveness of the combined treatment with Hsp90 inhibitor and heavy ion irradiation
- Author(s)
  Ryuichi OKayasu, Aya Masaoka, Hirokazu Hirakawa, Hiroshi Fujisawa, Shigeaki Sunada, Ryoichi Hirayama, Miho Noguchi, Huizi Li, and Akira Fujimori
- Organizer
  American Association for Cancer Research Annual Meeting
- Place of Presentation
  San Diego Convention Center, CA USA
- Year and Date
  2014-04-05 – 2014-04-09
- Data Source
  KAKENHI-PROJECT-24249067

1. KURIMASA Akihiro (80343276)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. NIWA Ohtaura (80093293)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. MASUTANI MITSUKO (60238904)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. FUJIMORI Hiroaki (00590043)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. FUJIMORI Akira (50314183)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
6. SAI Sei (20342735)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. YAJIMA Hirohiko (30261895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. YAMADA Shigeru (80311380)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 安藤興一 (00159526)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. 窪田宣雄 (20046139)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. JEGGO Penny

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. NICKOLOFF Jac

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. Lee Younghyun

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
14. 正岡綾

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
15. 砂田成章

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. 平川博一

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
17. Li Huizi

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
18. 窪田宜夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
19. 川田哲也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

OKAYASU Ryuichi 岡安 隆一

RYUICHI Okayasu 岡安 隆一

Research Projects

Research Products

Co-Researchers

Basic research to explore factors to improve effectiveness of radiation therapyPrincipal Investigator

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Molecular targeted drug discovery for cancer cell radiosensitization using RNA technology

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Research for poly(ADP-ribosylation) as a potential cancer therapeutic target

Principal Investigator

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Molecular targeted drug discovery for cancer cell radiosensitization using RNA aptamars

Principal Investigator

Project Period (FY)

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Research for radio-sensitizers which specifically attack tumor cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

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Research Institution

[Book] HIMAC20年の歩み: HIMAC20周年記念 研究成果要覧 １セクション担当 (p27-34)2015

Author(s)

Total Pages

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Data Source

[Book] Stress-Induced Mutagenesis2013

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[Book] 癌の臨床(6月号の1章執筆)2007

Author(s)

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Description

Data Source

[Book] 癌の臨床(6月号の一部を執筆)2007

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Total Pages

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[Book] 放射線生物研究 41巻 (1章執筆)2006

Author(s)

Publisher

Description

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[Book] 日経サイエンス(1監訳+1自己原稿)2006

Author(s)

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Data Source

[Book] 放射線生物研究 40巻 (1章執筆)2005

Author(s)

Publisher

Description

Data Source

[Journal Article] The complexity of DNA double strand break is a crucial factor for activating ATR signaling pathway for G2/M checkpoint regulation regardless of ATM function2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] DNA Damage Response Proteins and Oxygen Modulate Prostaglandin E2 Growth Factor Release in Response to Low and High LET Ionizing Radiation.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] VE-821, an ATR inhibitor, causes radiosensitization in human tumor cells irradiated with high LET radiation.2015

Author(s)

OKAYASU Ryuichi 岡安隆一

RYUICHI Okayasu 岡安隆一

[Book] HIMAC20年の歩み: HIMAC20周年記念　研究成果要覧１セクション担当 (p27-34)2015