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Hanaoka Hirofumi  花岡 宏史

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… Alternative Names

HANAOKA Hirofumi  花岡 宏史

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Researcher Number 50361390
Other IDs
Affiliation (Current) 2025: 関西医科大学, 附属光免疫医学研究所, 教授
Affiliation (based on the past Project Information) *help 2023 – 2024: 関西医科大学, 附属光免疫医学研究所, 教授
2020 – 2022: 関西医科大学, 医学部, 教授
2016 – 2019: 群馬大学, 大学院医学系研究科, 特任准教授
2014 – 2016: 群馬大学, 医学(系)研究科(研究院), 特任准教授
2015: 群馬大学, 大学院医学研究科, 准教授 … More
2014: 群馬大学, 医学(系)研究科(研究院), その他
2014: 千葉大学, 薬学研究科, 助教
2011 – 2013: 千葉大学, 薬学研究科(研究院), 助教
2012: 千葉大学, 大学院・薬学研究府, 助教
2011 – 2012: 千葉大学, 大学院・薬学研究院, 助教
2011: 千葉大学, 助教
2010: 群馬大学, 大学院・医学系研究科, 助教
2010: 群馬大学, 大学院・医学系研究科, 寄附講座教員
2008: Gunma University, 大学院医学系研究科, 助教
2007 – 2008: Gunma University, 大学院・医学系研究科, 助教
2007: 群馬大学, 医学系研究科, 助教
2006: 群馬大学, 大学院医学系研究科, 助手
2005: 群馬大学, 大学院・医学系研究科, 助手 Less
Review Section/Research Field
Principal Investigator
Radiation science / Basic Section 52040:Radiological sciences-related / Medium-sized Section 52:General internal medicine and related fields
Except Principal Investigator
Radiation science / Basic Section 52040:Radiological sciences-related / Nuclear engineering / 医学物理学・放射線技術学 / Chemistry related to living body
Keywords
Principal Investigator
アミノ酸 / チェレンコフ光 / 光免疫療法 / At-211 / 内用放射線療法 / 抗体 / アポトーシス / プレターゲティング / 核医学治療 / クリック反応 … More / 放射性薬剤 / アスタチン-211 / 薬剤併用効果 / α線 / 体内動態制御 / 放射性医薬品・造影剤 / 放射性医薬品 / 有機化学 / 放射性同位元素 / 癌 / 薬学 / 診断 / がん / 放射免疫療法 / 治療 / RI標識抗体 / 固形癌 / テクネシウム / 核医学診断 / 腫瘍 … More
Except Principal Investigator
PET / SPECT / 癌 / RI内用療法 / がん細胞 / がん / Cu-64 / 血液クリアランス / トリプルネガティブ乳癌 / 体内動態 / 分子イメージング / 放射線 / 褐色細胞腫 / ペプチド / キレート剤 / がん治療 / PET診断 / Cu-67 / クリックケミストリ― / クリックケミストリー / トリプルネガティブ乳がん / 内用放射線療法 / 放射線感受性 / 低酸素イメージング / 重粒子線治療 / 画像誘導放射線治療 / Cu-ATSM / 悪性腫瘍 / 抗酸化能 / 64Cu-ATSM / 炭素イオン線 / カーボンナノチューブ / 自己集合型 / 超音波造影剤 / PETイメージング / ペプチド薬剤 / ペプチド創薬 / スクリーニング / 医薬品開発 / 放射性同位体 / MRI造影剤 / 核磁気共鳴画像(MRI) / がん特異的 / Gd造影剤 / 放射性医薬品・造影剤 / アビジン / 抗VEGF抗体 / 内照射治療 / ガリウム / 標識薬剤 / 腎臓 / 治療 / ナノバブル / 腫瘍特異的 / 微小気泡 / 超音波 / 画像解析 / 腎機能 / 脳機能 / 小動物イメージング / 核医学 / 定量測定 / 小動物用イメージング装置 / 半導体検出器 / 内用放射線治療 / オージェ電子 / Br-77 / 核医学(PET を含む) / キャリアタンパク質 / 比放射能 / 抗体 / アイソトープ治療 / 脳神経疾患 / MRI / iPS細胞 / 画像 / 神経内分泌腫瘍 / イメージング / Br-76 / 寄生虫学 / バイオイメージング / 生体関連化学 / 高分子合成化学 / ナノスフェア / 微粒子 / マラリア / 生体機能材料 / 薬物徐放性材料 Less
  • Research Projects

    (25 results)
  • Research Products

    (56 results)
  • Co-Researchers

    (32 People)
  •  核医学治療と光免疫療法を融合した革新的がん治療法の創生Principal Investigator

    • Principal Investigator
      花岡 宏史
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Kansai Medical University
  •  Development of a highly effective target alpha therapy with At-211-labeled amino acid derivativePrincipal Investigator

    • Principal Investigator
      Hanaoka Hirofumi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Kansai Medical University
  •  Development of photoimmunotherapy that not require external light irradiationPrincipal Investigator

    • Principal Investigator
      Hanaoka Hirofumi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Kansai Medical University
  •  64Cu-ATSM Predicts Efficacy of Carbon Ion Radiotherapy Associated with Cellular Antioxidant Capacity

    • Principal Investigator
      Ohno Tatsuya
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Gunma University
  •  Development of an targeted radionuclide therapy of triple-negative breast cancer for clinical application

    • Principal Investigator
      Katsumata Natsumi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Gunma University
  •  Development of self-assembling and tumor-specific ultrasound contrast agents using carbon nanotubes

    • Principal Investigator
      Tsushima Yoshito
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Gunma University
  •  Development of a versatile alpha particle therapy using At-211 labeled amino acids with controlled pharmacokineticsPrincipal Investigator

    • Principal Investigator
      HANAOKA Hirofumi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Kansai Medical University
      Gunma University
  •  Evaluation of Cu-64, Cu-67 Ions for Cancer Imaging and Therapy

    • Principal Investigator
      SUGO Yumi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      National Institutes for Quantum and Radiological Science and Technology
  •  Development of a radioimmunotherapy (RIT) agent for triple-negative breast cancer

    • Principal Investigator
      Katsumata Natsumi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Gunma University
  •  理論的な薬剤設計に基づくがん特異的Gd造影剤の開発

    • Principal Investigator
      島田 健裕
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Gunma University
  •  Development of a novel tumor-targeting ultrasound contrast agent and its application as a carrier for the drug delivery system

    • Principal Investigator
      Tsushima Yoshito
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Gunma University
  •  Development of highly-sensitive apoptosis imaging agent based on new drug designPrincipal Investigator

    • Principal Investigator
      Hanaoka Hirofumi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Gunma University
  •  A new approach using radioisotopes for peptide drug discovery

    • Principal Investigator
      ISHIOKA NORIKO
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Nuclear engineering
    • Research Institution
      National Institutes for Quantum and Radiological Science and Technology
      Japan Atomic Energy Agency
  •  Studies on PET Imaging of Cancer Using Cu-64 Ions

    • Principal Investigator
      SUGO Yumi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      National Institutes for Quantum and Radiological Science and Technology
      Japan Atomic Energy Agency
  •  Engineering radiolabeled antibody fragments for enhanced tumor to kidney ratio

    • Principal Investigator
      Uehara Tomoya
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Radiation science
    • Research Institution
      Chiba University
  •  Quantitative measurement of a new small animal SPECT/CT scanner with a semiconductor detector

    • Principal Investigator
      KOBAYASHI Masato
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      医学物理学・放射線技術学
    • Research Institution
      Kanazawa University
  •  Development of a novel chelating agent suitable for the prelabeling to establish a generic method for preparation of radiolabeled antibodies.Principal Investigator

    • Principal Investigator
      HANAOKA Hirofumi
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Radiation science
    • Research Institution
      Chiba University
  •  99mTc-labeled probes imitating antibodies

    • Principal Investigator
      ARANO Yasushi
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Radiation science
    • Research Institution
      Chiba University
  •  Basic investigation on radionuclide therapy with auger electron by using Br-77 labeled MBBG

    • Principal Investigator
      WATANABE Shigeki
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Radiation science
    • Research Institution
      Japan Atomic Energy Agency
  •  Cell tracking technique of iPS cells and clinical application using PET and MRI

    • Principal Investigator
      ENDO Keigo
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Radiation science
    • Research Institution
      Kyoto College of Medical Science
      Gunma University
  •  Development of Br-76-labeled amino acid derivatives for imaging tumorsPrincipal Investigator

    • Principal Investigator
      HANAOKA Hirofumi
    • Project Period (FY)
      2010 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Radiation science
    • Research Institution
      Chiba University
      Gunma University
  •  Synthesis of Br-76 labeled MBBG and applications to tumor imaging with PET

    • Principal Investigator
      WATANABE Shigeki
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Radiation science
    • Research Institution
      Japan Atomic Energy Agency
  •  Synthetic studies of long-acting nano-particles toward a novel malaria vaccine to realize the immunity condition in malaria endemic area

    • Principal Investigator
      OKU Hiroyuki
    • Project Period (FY)
      2007 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Chemistry related to living body
    • Research Institution
      Gunma University
  •  Mechanism elucidation of the lethaleffect of radiolabeled antibody to solid tumor, and searching the factor enhanced this effectPrincipal Investigator

    • Principal Investigator
      HANAOKA Hirofumi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Radiation science
    • Research Institution
      Gunma University
  •  PET薬剤に代わる新しいがん診断用薬剤、99mTc標識アミノ酸誘導体の開発Principal Investigator

    • Principal Investigator
      花岡 宏史
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Radiation science
    • Research Institution
      Gunma University

All 2021 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Patent

  • [Journal Article] 64Cu-ATSM Predicts Efficacy of Carbon Ion Radiotherapy Associated with Cellular Antioxidant Capacity2021

    • Author(s)
      Nachankar Ankita、Oike Takahiro、Hanaoka Hirofumi、Kanai Ayaka、Sato Hiro、Yoshida Yukari、Obinata Hideru、Sakai Makoto、Osu Naoto、Hirota Yuka、Takahashi Akihisa、Shibata Atsushi、Ohno Tatsuya
    • Journal Title

      Cancers

      Volume: 13 Issue: 24 Pages: 6159-6159

    • DOI

      10.3390/cancers13246159

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08091, KAKENHI-PROJECT-17H04713, KAKENHI-PUBLICLY-20H04879, KAKENHI-PROJECT-20K21536, KAKENHI-PUBLICLY-21H05504, KAKENHI-PROJECT-23K21749
  • [Journal Article] Enhancing the Therapeutic Effect of 2-211At-astato-α-methyl-L-phenylalanine with Probenecid Loading2021

    • Author(s)
      Hanaoka Hirofumi、Ohshima Yasuhiro、Suzuki Hiroyuki、Sasaki Ichiro、Watabe Tadashi、Ooe Kazuhiro、Watanabe Shigeki、Ishioka Noriko S.
    • Journal Title

      Cancers

      Volume: 13 Issue: 21 Pages: 5514-5514

    • DOI

      10.3390/cancers13215514

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H02871
  • [Journal Article] Enhancing the accumulation level of 3-[<sup>18</sup>F]fluoro-L-α- methyltyrosine in tumors by preloading probenecid.2021

    • Author(s)
      Kanai A, Hanaoka H, Yamaguchi A, Mahendra I, Palangka C, Ohshima Y, Higuchi T, Tsushima Y.
    • Journal Title

      Nucl Med Biol.

      Volume: 104-105 Pages: 47-52

    • DOI

      10.1016/j.nucmedbio.2021.11.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08220, KAKENHI-PROJECT-21H02871
  • [Journal Article] Immuno-PET imaging for non-invasive assessment of cetuximab accumulation in non-small cell lung cancer2019

    • Author(s)
      Yamaguchi A, Achmad A, Hanaoka H, Heryanto YD, Bhattarai A, Ratianto, Khongorzul E, Shintawati R, Kartamihardja AAP, Kanai A, Sugo Y, S Ishioka N, Tetsuya H, Tsushima Y
    • Journal Title

      BMC Cancer

      Volume: 19 Issue: 1 Pages: 1-8

    • DOI

      10.1186/s12885-019-6238-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K17224, KAKENHI-PROJECT-17K10458
  • [Journal Article] Bevacizumab Radioimmunotherapy (RIT) with Accelerated Blood Clearance Using the Avidin Chase2018

    • Author(s)
      Yudistiro Ryan、Hanaoka Hirofumi、Katsumata Natsumi、Yamaguchi Aiko、Tsushima Yoshito
    • Journal Title

      Molecular Pharmaceutics

      Volume: 15 Issue: 6 Pages: 2165-2173

    • DOI

      10.1021/acs.molpharmaceut.8b00027

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10269
  • [Journal Article] Medical application of radiohalogenated peptides : synthesis and in vitro evaluation of F(p-131I)KCCYSL for targeting HER22016

    • Author(s)
      I. Sasaki, S. Watanabe, Y. Ohshima, Y. Sugo, K. Yamada, H. Hanaoka, N. S. Ishioka
    • Journal Title

      Peptide Science 2015

      Volume: 52 Pages: 243-246

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26289369
  • [Journal Article] Exploring of peptides with affinity to HER2 from random peptide libraries using radioisotope;Random hexapeptide libraries with fixed amino acid sequence at 1 and 2 positions2015

    • Author(s)
      I. Sasaki, H. Hanaoka, K. Yamada, Sh. Watanabe, Y. Sugo, Y. Ohshima, H. Suzuki, N. S. Ishioka
    • Journal Title

      Peptide Science 2014

      Volume: - Pages: 257-260

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26289369
  • [Journal Article] 67/68Ga-labeling Agent that Liberates 67/68Ga-NOTA-methionine by Lysosomal Proteolysiso of Parental Low Molecular Weight Polypeptides to Reduce Renal Radioactivity Levels2014

    • Author(s)
      Tomoya Uehara, Takemi Rokugawa, Mai Kinoshita, Aouki Nemoto, Guerra Gomez Fransisco Lazaro, Hirofumi Hanaoka, and Yasushi Arano
    • Journal Title

      Bioconjugate Chem.

      Volume: 25 Issue: 11 Pages: 2038-2045

    • DOI

      10.1021/bc5004058

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25713045
  • [Journal Article] Appropriate collimators in a small animal SPECT scanner with CZT detector.2013

    • Author(s)
      Higaki Y, Kobayashi M, Uehara K, Hanaoka H, Arano Y, Kawai K.
    • Journal Title

      Annals of Nuclear Medicine

      Volume: 27 Issue: 3 Pages: 271-278

    • DOI

      10.1007/s12149-012-0681-5

    • NAID

      10031168094

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24601008, KAKENHI-PROJECT-24659558, KAKENHI-PROJECT-25293260
  • [Journal Article] Biological evaluation of 3-[18F]fluoro-α-methyl-D-tyrosine (D-[18F]FAMT) as a novel amino acid tracer for positron emission tomography.2013

    • Author(s)
      Ohshima Y
    • Journal Title

      Ann Nucl Med

      Volume: 27 Issue: 4 Pages: 314-324

    • DOI

      10.1007/s12149-013-0687-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300334, KAKENHI-PROJECT-22689035, KAKENHI-PROJECT-24390217, KAKENHI-PROJECT-24591198, KAKENHI-PROJECT-24659116, KAKENHI-PROJECT-24659573, KAKENHI-PUBLICLY-25136714, KAKENHI-PROJECT-25461801, KAKENHI-PUBLICLY-23136509
  • [Journal Article] In vivo therapeutic effect of CDH3/P-cadherin-targeting radioimmunotherapy2012

    • Author(s)
      Yoshioka H, Yamamoto S, Hanaoka H, Iida Y, Paudyal P, Higuchi T, Tominaga H, Oriuchi N, Nakagawa H, Shiba Y, Yoshida K, Osawa R, Katagiri T, Tsunoda T, Nakamura Y, Endo K
    • Journal Title

      Cancer Immunol Immunother

      Volume: 61 Issue: 8 Pages: 1211-1220

    • DOI

      10.1007/s00262-011-1186-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659217, KAKENHI-PROJECT-24591824, KAKENHI-PROJECT-24659573
  • [Journal Article] Predicting cetuximab accumulation in KRAS wild-type and KRAS mutant colorectal cancer using 64Cu-labeled cetuximab positron emission tomography2012

    • Author(s)
      Achmad A
    • Journal Title

      Cancer Sci

      Volume: 103 Issue: 3 Pages: 600-605

    • DOI

      10.1111/j.1349-7006.2011.02166.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591593, KAKENHI-PROJECT-22659217
  • [Journal Article] Preparation and biological evaluation of 3-[76Br] bromo-α-methyl-L-tyrosine, a novel tyrosine analog for positron emission tomography imaging of tumors2011

    • Author(s)
      Ohshima Y, Hanaoka H, Watanabe S, Sugo Y, Watanabe S, Tominaga H, Oriuchi N, Endo K, Ishioka NS
    • Journal Title

      Nucl Med Biol

      Volume: 38 Issue: 6 Pages: 857-865

    • DOI

      10.1016/j.nucmedbio.2011.02.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659217, KAKENHI-PROJECT-22689035
  • [Journal Article] Positron emission tomography imaging and biodistribution of vascular endothelial growth factor with 64Cu-labeled bevacizumab in colorectal cancer xenografts2011

    • Author(s)
      Paudyal B, Paudyal P, Oriuchi N, Hanaoka H, Tominaga H, Endo K
    • Journal Title

      Cancer Sci

      Volume: 102 Issue: 1 Pages: 117-121

    • DOI

      10.1111/j.1349-7006.2010.01763.x

    • NAID

      10029288704

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659217
  • [Journal Article] PET Imaging of Norepinephrine Transporter-expressing Tumors Using 76Br-m-bromobenzylguanidine2010

    • Author(s)
      S.Watanabe, H.Hanaoka, J.X.Liang
    • Journal Title

      The Journal of Nuclear Medicine 51

      Pages: 1472-1479

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21791227
  • [Journal Article] Radioimmunotherapy of solid tumors targeting a cell-surface protein, FZD10: Therapeutic efficacy largely depends on radiosensitivity2009

    • Author(s)
      Hanaoka H, Katagiri T, Fukukawa C, Yoshioka H, Yamamoto S, Iida Y, Higuchi T, Oriuchi N, Paudyal B, Paudyal P, Nakamura Y, Endo K
    • Journal Title

      Ann Nucl Med 2009(in press) 23

    • NAID

      10025136774

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790855
  • [Journal Article] Radioimmunotherapy of solid tumors targeting a cell-surface protein, FZD10 : Therapeutic efficacy largely depends on radiosensitivity2009

    • Author(s)
      Hanaoka H. et.al.
    • Journal Title

      Annals of Nuclear Medicine 23(in press)

    • NAID

      10025136774

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790855
  • [Journal Article] Nano-Particle Materials Prepared From a Synthetic Antigenic Sequence of Plasmodium falciparum Enolase. Peptide Scienece 20082009

    • Author(s)
      Oku, H., Yamada, K., Hanaoka, H., Kano, S., ら.
    • Journal Title

      The Japanese Peptide Society(M. Nomizu Ed.)

      Pages: 439-442

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19550158
  • [Journal Article] Nano-Particle Materials Prepared From a Synthetic Antigenic Sequence of Plasmodium falciparum Enolase2009

    • Author(s)
      H. Oku, K. Yamada, K. Kobayashi, R. Katakai, M. Ashfaq, H. Hanaoka, Y. Iida, K. Endo, S. Hasegawa, Y. Maekawa, K. Yano, S. Kano, M .Suzuki.
    • Journal Title

      In Peptide Science 2008, M. Nomizu, Ed.; Protein Research Foundation : Osaka

      Pages: 422-439

    • NAID

      10027166661

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19550158
  • [Journal Article] Synthesis and Properties of Novel Amphiphilic Block Copolymers Consisting of Metal Ion Coordinating Depsipeptides and Poly(ethylene glycol)2008

    • Author(s)
      K. Arai, H. Oku, K. Yamada, H. Hanaoka, Y. Iida, K. Endo, K. Kohama, R. Katakai.
    • Journal Title

      Peptide Scienece 2007 ; S. Aimoto & S. Ono, Eds.; The Japanese Peptide Society : Osaka

      Pages: 437-440

    • NAID

      10021907282

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19550158
  • [Patent] 両親媒性の高分子配位子によって安定化された高分子錯体および検査用組成物および医薬組成物2007

    • Inventor(s)
      奥浩之, 山田圭一, 片貝良一, 花岡宏史, 飯田靖彦, 織内昇, 遠藤啓吾, 早川晃一, 小濱一弘
    • Industrial Property Rights Holder
      国立大学法人群馬大学
    • Filing Date
      2007-06-13
    • Data Source
      KAKENHI-PROJECT-19550158
  • [Presentation] Usefulness of Cu-64-labeled cetuximab PET screening to predict response to cetuximab treatment in non-small cell lung cancer2018

    • Author(s)
      H. Hanaoka, A. Achmad, A. Yamaguchi, H. T. Nguyen, Y. Sugo, N. S. Ishioka, Y. Tsushima
    • Organizer
      12th World Congress of the World Federation of Nuclear Medicine and Biology(WFNMB2018)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10458
  • [Presentation] Radioimmunotherapy of triple negative breast cancer using 90Y-DTPA-bevacizumab2017

    • Author(s)
      Hirofumi Hanaoka, Ryan Yudistiro, Aiko Yamaguchi, Tetsuya Higuchi, Yoshito Tsushima
    • Organizer
      第22回放射性薬剤国際シンポジウム(ISRS 2017)
    • Data Source
      KAKENHI-PROJECT-16K10269
  • [Presentation] Improvement and optimization of clinically promising 76Br isolation using dry distillation approach for its future automation2017

    • Author(s)
      Sh. Watanabe, A. Shimada, Sa. Watanabe, H. Hanaoka, N. S. Ishioka
    • Organizer
      the International union of materials research society-International conference of advanced materials (IUMRS-ICAM) 2017
    • Place of Presentation
      京都大学吉田キャンパス(京都府堺区)
    • Year and Date
      2017-08-27
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26289369
  • [Presentation] Cu-64イオンによるがんのPETイメージング2017

    • Author(s)
      須郷由美、大島康宏、山口藍子、花岡宏史、石岡典子
    • Organizer
      第5回メタロミクス研究フォーラム
    • Data Source
      KAKENHI-PROJECT-17K10458
  • [Presentation] 64/67Cuイオンのがん診断/治療用薬剤としての有用性の検討2017

    • Author(s)
      須郷由美、大島康宏、山口藍子、花岡宏史、塚田和明、橋本和幸、川端方子、佐伯秀也、永井泰樹、石岡典子
    • Organizer
      第1回日本核医学会分科会 放射性薬品科学研究会/第17回放射性医薬品・画像診断薬研究会
    • Data Source
      KAKENHI-PROJECT-17K10458
  • [Presentation] 131I標識ペプチドの医学的応用-HER2標的としたF(p-131I)KCCYSLの合成とin vitro評価-2016

    • Author(s)
      佐々木一郎, 渡辺茂樹, 大島康宏, 須郷由美, 山田圭一, 花岡宏史, 石岡典子
    • Organizer
      第53回アイソトープ・放射線研究発表会
    • Place of Presentation
      東京大学弥生講堂(東京都文京区)
    • Year and Date
      2016-07-07
    • Data Source
      KAKENHI-PROJECT-26289369
  • [Presentation] サイクロトロンで製造する放射性銅のがんの診断・治療への応用2016

    • Author(s)
      須郷由美、大島康宏、山口藍子、花岡宏史、塚田和明、橋本和幸、川端方子、佐伯秀也、永井泰樹、石岡典子
    • Organizer
      第59回放射線化学討論会
    • Place of Presentation
      高崎量子応用研究所(群馬県・高崎市)
    • Year and Date
      2016-09-20
    • Data Source
      KAKENHI-PROJECT-26461812
  • [Presentation] Cu-64イオンを用いたがんのPETイメージング2015

    • Author(s)
      須郷由美、大島康宏、山口藍子、花岡宏史、石岡典子
    • Organizer
      2015放射化学会年会・第59回放射化学討論会
    • Place of Presentation
      東北大学(宮城県・仙台市)
    • Year and Date
      2015-09-25
    • Data Source
      KAKENHI-PROJECT-26461812
  • [Presentation] Medical application of radiohalogenated peptides : synthesis and in vitro evaluation of F(p-131I)KCCYSL for targeting HER22015

    • Author(s)
      I. Sasaki, S. Watanabe, Y. Ohshima, Y. Sugo, K. Yamada, H. Hanaoka, N. S. Ishioka
    • Organizer
      52nd Japanese Peptide Symposium
    • Place of Presentation
      東海大学(神奈川県平塚市)
    • Year and Date
      2015-11-15
    • Data Source
      KAKENHI-PROJECT-26289369
  • [Presentation] 放射性同位元素を利用したがんのペプチド創薬に関する研究2014

    • Author(s)
      佐々木一郎, 花岡宏史, 山田圭一, 渡辺茂樹, 須郷由美, 大島康宏, 石岡典子
    • Organizer
      日本原子力学会関東甲越支部、第13 回若手研究者発表討論会
    • Place of Presentation
      電力中央研究所(東京都、狛江市)
    • Year and Date
      2014-11-10
    • Data Source
      KAKENHI-PROJECT-26289369
  • [Presentation] RI 標識ランダムペプチドライブラリーを利用したがん親和性ペプチドの新規選抜法に関する 研究2014

    • Author(s)
      佐々木一郎, 花岡宏史, 山田圭一, 渡辺茂樹, 須郷由美, 大島康宏, 石岡典子
    • Organizer
      日本化学会関東支部群馬地区地域懇談会
    • Place of Presentation
      群馬大学(群馬県、桐生市)
    • Year and Date
      2014-12-12
    • Data Source
      KAKENHI-PROJECT-26289369
  • [Presentation] A-Ga-68-labeling reagent liberating Ga--58-NOTA-conjugated methionine from low molecular weight polypeptides in lysosomes for low renal radioactivity levels2013

    • Author(s)
      Tomoya Uehara,Mai Kinoshita, Takemi Rokugawa, Guerra Gomez Fransicsco L, Hirofumi Hanaoka, Yasushi Arano
    • Organizer
      The 20 th International Symposium on Radiopharmaceutical Sciences
    • Place of Presentation
      Jeju (Korea)
    • Data Source
      KAKENHI-PROJECT-25713045
  • [Presentation] Development of ^<76>Br-labeled α-methyl L-phenylalanine for imaging tumors2013

    • Author(s)
      Hanaoka H, Watanabe S, Ohshima Y, Suzuki Y, Yamaguchi A, Uehara T, Ishioka NS, Tsushima Y, Endo K, Arano Y
    • Organizer
      2013 Society of Nuclear Medicine Annual Meeting
    • Place of Presentation
      Vancouver, Canada
    • Data Source
      KAKENHI-PROJECT-22689035
  • [Presentation] 優れた尿排泄性を有する111In標識馬尿酸誘導体の合成と基礎的評価2013

    • Author(s)
      鈴木博元,金井彩香,上原知也,花岡宏史,荒野泰
    • Organizer
      日本薬学会第133回総会
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-30
    • Data Source
      KAKENHI-PROJECT-23659578
  • [Presentation] Development of 76Br-labeled α-methyl L-phenylalanine for imaging tumors2013

    • Author(s)
      花岡宏史
    • Organizer
      米国会医学会
    • Place of Presentation
      バンクーバー (カナダ)
    • Data Source
      KAKENHI-PROJECT-22689035
  • [Presentation] 腎放射活性の低減を目的とした放射性ガリウム標識RGDペプチドの開発2013

    • Author(s)
      趙 天会,上原知也,根本創紀,花岡宏史,荒野 泰
    • Organizer
      第13回放射性医薬品・画像診断研究会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-25713045
  • [Presentation] 小動物用SPECT/CT装置におけるパラレルとピンホールコリメータの比較2012

    • Author(s)
      檜垣佑輔,小林正和,上原知也,花岡宏史,荒野泰,川井恵一
    • Organizer
      第52回日本核医学会学術総会
    • Place of Presentation
      さっぽろ芸術文化の館・ロイトン札幌 (北海道)
    • Data Source
      KAKENHI-PROJECT-24601008
  • [Presentation] 3-[^<76>Br]bromo-α-methyl-D-tyrosine の腫瘍PET イメージング薬剤としての有用性の評価2012

    • Author(s)
      大島康宏, 花岡宏史, 渡邉茂樹, 渡辺智, 須郷由美, 織内昇, 遠藤啓吾, 石岡典子
    • Organizer
      第52回日本核医学会総会
    • Place of Presentation
      札幌
    • Year and Date
      2012-10-12
    • Data Source
      KAKENHI-PROJECT-22689035
  • [Presentation] 3-[^<18>F]fluoro-α-methyl-D-tyrosine によるD 体アミノ酸トレーサーの低腎集積機構の検討2011

    • Author(s)
      大島康宏, 花岡宏史, 富永英之, 渡邉茂樹, 織内昇, 遠藤啓吾, 石岡典子
    • Organizer
      第51回日本核医学会総会
    • Place of Presentation
      つくば
    • Year and Date
      2011-10-28
    • Data Source
      KAKENHI-PROJECT-22689035
  • [Presentation] PET imaging of renal and bladder tumor with 3-[^<18>F]Fluoro-α-methyl- D-tyrosine (D-[^<18>F]FAMT)2011

    • Author(s)
      大島康宏, 花岡宏史, 渡邉茂樹, 織内昇, 遠藤啓吾, 石岡典子
    • Organizer
      第70回日本癌学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-22689035
  • [Presentation] Development of ^<76>Br-labeled amino acid derivative for PET imaging of tumor2010

    • Author(s)
      Hanaoka H, et al
    • Organizer
      第69回日本癌学会学術集会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2010-09-24
    • Data Source
      KAKENHI-PROJECT-22689035
  • [Presentation] Development of ^<76>Br-labeled amino acid derivative for PET imaging of tumor2010

    • Author(s)
      花岡宏史, 渡邉茂樹, 大島康宏, 織内昇, 石岡典子, 遠藤啓吾
    • Organizer
      第69回日本癌学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-24
    • Data Source
      KAKENHI-PROJECT-22689035
  • [Presentation] 熱帯熱マラリア原虫に由来する抗原ペプチドのナノ微粒子化と抗原性に関する研究2009

    • Author(s)
      奥浩之, 矢野和彦, 花岡宏史, 長谷川伸, 山田圭一, 片貝良一, 飯田靖彦, 遠藤啓吾, 前川康成, 狩野繁之, 鈴木守
    • Organizer
      日本化学会第89春期年会
    • Place of Presentation
      日本大学、千葉県船橋市
    • Year and Date
      2009-03-29
    • Data Source
      KAKENHI-PROJECT-19550158
  • [Presentation] 熱帯熱マラリア原虫に由来する抗原ペプチドのナノ微粒子化と抗原性に関する研究2009

    • Author(s)
      奥浩之, 花岡宏史, 山田圭一, 狩野繁之, ら.
    • Organizer
      日本化学会第89春期年会
    • Place of Presentation
      船橋市
    • Year and Date
      2009-03-29
    • Data Source
      KAKENHI-PROJECT-19550158
  • [Presentation] 熱帯熱マラリア原虫由来の人工抗原を内包した生分解性ナノ微粒子に関する研究2008

    • Author(s)
      奥浩之, 山田圭一, 片貝良一, 花岡宏史, 飯田靖彦, 遠藤啓吾, 長谷川伸, 前川康成, 矢野和彦, 狩野繁之, 鈴木守
    • Organizer
      第3回分子イメージング学会
    • Place of Presentation
      大宮ソニックシティ、埼玉県さいたま市
    • Year and Date
      2008-05-23
    • Data Source
      KAKENHI-PROJECT-19550158
  • [Presentation] 熱帯熱マラリア原虫に由来する抗原ペプチドの蛍光標識化とナノ微粒子研究2008

    • Author(s)
      奥浩之, 山田圭一, 花岡宏史, 狩野繁之, ら.
    • Organizer
      第8回放射性医薬品・画像診断薬研究会
    • Place of Presentation
      京都市
    • Year and Date
      2008-12-06
    • Data Source
      KAKENHI-PROJECT-19550158
  • [Presentation] 熱帯熱マラリア原虫由来の人工抗原を用いた生分解性ナノ微粒子の作成と性質2008

    • Author(s)
      奥浩之, 山田圭一, 花岡宏史, 狩野繁之, ら.
    • Organizer
      第67回日本寄生虫学会東日本支部大会
    • Place of Presentation
      浜松市
    • Year and Date
      2008-10-04
    • Data Source
      KAKENHI-PROJECT-19550158
  • [Presentation] 熱帯熱マラリア原虫由来の人工抗原を内包した生分解性ナノ微粒子に関する研究2008

    • Author(s)
      奥浩之, 山田圭一, 花岡宏史, 狩野繁之, ら.
    • Organizer
      第3回分子イメージング学会
    • Place of Presentation
      さいたま市
    • Year and Date
      2008-05-23
    • Data Source
      KAKENHI-PROJECT-19550158
  • [Presentation] 熱帯熱マラリア原虫由来の人口抗原を用いたナノ微粒子研究2008

    • Author(s)
      奥浩之, 山田圭一, 小林京子, 片貝良一, 花岡宏史, 飯田靖彦, 遠藤啓吾, 長谷川伸, 前川康成, 矢野和彦, 狩野繁之, 鈴木守
    • Organizer
      第45回ペプチド討論会
    • Place of Presentation
      タワーホール江戸堀、東京都江戸川区
    • Year and Date
      2008-10-30
    • Data Source
      KAKENHI-PROJECT-19550158
  • [Presentation] 熱帯熱マラリア原虫に由来する抗原ペプチドの蛍光標識化とナノ微粒子研究2008

    • Author(s)
      奥浩之, 山田圭一, 片貝良一, 花岡宏史, 飯田靖彦, 遠藤啓吾, 長谷川伸, 前川康成, 矢野和彦, 狩野繁之, 鈴木守
    • Organizer
      第8回放射性医薬品・画像診断薬研究会
    • Place of Presentation
      京都テルサ、京都市
    • Year and Date
      2008-12-06
    • Data Source
      KAKENHI-PROJECT-19550158
  • [Presentation] 熱帯熱マラリア原虫由来の人工抗原を用いた生分解性ナノ微粒子の作成と性質2008

    • Author(s)
      奥浩之, 山田圭一, 片貝良一, 花岡宏史, 飯田靖彦, 遠藤啓吾, 矢野和彦, 狩野繁之, 鈴木守
    • Organizer
      第68回日本寄生虫学会東日本支部大会
    • Place of Presentation
      アクトシティ浜松、静岡県浜松市
    • Year and Date
      2008-10-04
    • Data Source
      KAKENHI-PROJECT-19550158
  • [Presentation] 熱帯熱マラリア原虫由来の人工抗原を内包した生分解性ナノ微粒子に関する研究2008

    • Author(s)
      奥浩之、山田圭一、片貝良一、花岡宏史、他8名
    • Organizer
      日本分子イメージング学会第3回総会学術集会
    • Place of Presentation
      さいたま市
    • Year and Date
      2008-05-23
    • Data Source
      KAKENHI-PROJECT-19550158
  • [Presentation] 腎放射活性の低減を目的とする低分子ポリペプチドGa標識薬剤に関する基礎的研究

    • Author(s)
      上原知也,横山幹,趙天会,花岡宏史,荒野泰
    • Organizer
      第54回日本核医学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2014-11-06 – 2014-11-08
    • Data Source
      KAKENHI-PROJECT-25713045
  • [Presentation] Isolation of 76Br from irradiated Cu2 76Se targets using dry distillation: evaluations and improvement for routine production

    • Author(s)
      Sh. Watanabe, Sa. Watanabe, Y. Ohshima, Y. Sugo, I. Sasaki, H. Hanaoka, N. S. Ishioka
    • Organizer
      15th International Workshop on Targetry and Target Chemistry
    • Place of Presentation
      Hotel Diplomat(Prague, Czech Republic)
    • Year and Date
      2014-08-17 – 2014-08-21
    • Data Source
      KAKENHI-PROJECT-26289369
  • [Presentation] Exploring of Peptides with Affinity to HER2 from Random Peptide Libraries Using Radioisotope: Random Hexapeptide Libraries with Fixed Amino Acid Sequence at 1 and 2 Positions

    • Author(s)
      佐々木一郎, 花岡宏史, 山田圭一, 渡辺茂樹, 須郷由美, 大島康宏, 鈴木博元, 石岡典子
    • Organizer
      第51 回ペプチド討論会
    • Place of Presentation
      徳島大学(徳島県、徳島市)
    • Year and Date
      2014-10-22 – 2014-10-24
    • Data Source
      KAKENHI-PROJECT-26289369
  • 1.  WATANABE Shigeki (10450305)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 11 results
  • 2.  YAMAGUCHI Aiko (80609032)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 5 results
  • 3.  YAMADA Keiichi (70323334)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 20 results
  • 4.  UEHARA Tomoya (10323403)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 5.  ISHIOKA NORIKO (30354963)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 9 results
  • 6.  KANO Shigeyuki (60233912)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 11 results
  • 7.  Tsushima Yoshito (20375546)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  Katsumata Natsumi (50588811)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 9.  SUGO Yumi (90354836)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 10.  大島 康宏 (00588676)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 10 results
  • 11.  渡部 直史 (90648932)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 12.  OKU Hiroyuki (20301749)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  YANO Kazuhiko (30392393)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 14.  ENDO Keigo (10115800)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 15.  YAMASHITA Mitsuaki (20433641)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  ARANO Yasushi (90151167)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  KOBAYASHI Masato (30444235)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 18.  KAWAI Keiichi (30204663)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 19.  Ohno Tatsuya (10344061)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 20.  中嶌 崇仁 (70375559)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  島田 健裕 (30573092)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  鈴木 博元 (00707648)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  織内 昇 (40292586)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  尾池 貴洋 (10643471)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 25.  橋本 和幸 (80414530)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 26.  金井 彩香 (10847495)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  小川 美香子 (20344351)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  小野 正博 (80336180)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  SASAKI Ichiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 30.  奧 浩之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 13 results
  • 31.  K AchmadA.P.
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 32.  樋口 徹也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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