SAITO Yukio 齊藤幸生

… Alternative Names

斉藤幸生サイトウユキオ

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Researcher Number	50377511
Affiliation (based on the past Project Information) *help	2014 – 2016: 山梨大学, 総合研究部, 助教 2012: 山梨大学, 医学工学総合研究部, 助教 2009 – 2012: 山梨大学, 大学院・医学工学総合研究部, 助教 2007 – 2008: 山梨大学, 医学部附属病院, 医員
Review Section/Research Field	Except Principal Investigator Circulatory organs internal medicine / Cardiovascular medicine
Keywords	Except Principal Investigator 炎症 / ノックアウトマウス / 心血管病 / 心筋梗塞 / 薬剤溶出性ステント / 冠動脈内皮機能障害 / TNF / 受容体 / ホスホリパーゼA2 / 分泌型ホスホリパーゼA2受容体 / 好中球 / 脂質メディエーター / 分泌型ホスホリパーゼA

long term outcome by reduced impairment of coronary endothelial function after new generation drug-eluting stent implantation
- Principal Investigator
  
  OBATA Jyun-Ei
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  University of Yamanashi
A study of role of phospholipase A2 receptor in pathogenosis ofcardiovascular diseases and development of new drug for cardiovascular diseases
- Principal Investigator
  
  KUGIYAMA Kiyotaka
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  University of Yamanashi
A study of role of phospholipase A2 in pathogenosis of cardiovascular diseases and development of new drug for cardiovascular diseases
- Principal Investigator
  
  KUGIYAMA Kiyotaka
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  University of Yamanashi

All 2013 2012 2011 2010 2009 2008 2007

All Journal Article Presentation

[Journal Article] Chronicdepletion of glutathione exacerbatesventricular remodelling and dysfunctionin the pressure-overloaded heart2013
- Author(s)
  Watanabe Y, Watanabe K, Kobayashi T,Saito Y, Fujioka D, Nakamura T, Obata JE,Kawabata K, Mishina H, Kugiyama K
- Journal Title
  
  Cardiovasc Res
  
  Volume: Vol. 97, No. 2 Pages: 282-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390158
[Journal Article] Group X secretory PLA2 in neutrophilsplays a pathogenic role in abdominalaortic aneurysms in mice2012
- Author(s)
  Watanabe K, Fujioka D, Saito Y, NakamuraT, Obata JE, Kawabata K, Watanabe Y,Mishina H, Tamaru S, Hanasaki K, KugiyamaK
- Journal Title
  
  Am J Physiol Heart Circ Physiol
  
  Volume: Vol.302, No. 1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390158
[Journal Article] Disruption of group IVAcytosolic phospholipase A(2) attenuatesmyocardial ischemia-reperfusion injurypartly through inhibition ofTNF-α-mediated pathway2012
- Author(s)
  Saito Y, Watanabe K, Fujioka D, NakamuraT, Obata JE, Kawabata K, Watanabe Y,Mishina H, Tamaru S, Kita Y, Shimizu T,Kugiyama K
- Journal Title
  
  Am J PhysiolHeart Circ Physiol
  
  Volume: Vol.302,No.10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390158
[Journal Article] Group V secretoryphospholipase A2 plays a pathogenic rolein myocardial ischaemia-reperfusioninjury2011
- Author(s)
  Yano T, Fujioka D, Saito Y, KobayashiT, Nakamura T, Obata JE, Kawabata K,Watanabe K, Watanabe Y, Mishina H, TamaruS, Kugiyama K
- Journal Title
  
  Cardiovasc Res
  
  Volume: Vol. 90,No. 2 Pages: 335-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390158
[Journal Article] Mice lacking the glutamate-cysteine ligase modifier subunit are susceptible to myocardial ischaemia-reperfusion injury.2010
- Author(s)
  Kobayashi T, Watanabe Y, Saito Y, Fujioka D, Nakamura T, Obata JE, Kitta Y, Yano T, Kawabata K, Watanabe K, Mishina H, Ito S, Kugiyama K.
- Journal Title
  
  Cardiovasc Res. 85,4
  
  Pages: 785-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390209
[Journal Article] Inhibition of secretory hospholipase A2 activity attenuates lipopolysaccharide-induced acute lung injury in a mouse model.2010
- Author(s)
  Sato R, Yamaga S, Watanabe K, Hishiyama S, Kawabata K, Kobayashi T, Fujioka D, Saito Y, Yano T, Watanabe K, Watanabe Y, Ishihara H, Kugiyama K.
- Journal Title
  
  Exp Lung Res. 36,4
  
  Pages: 191-200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390209
[Journal Article] Rapid improvement of carotid plaque echogenicity within 1 month of pioglitazone treatment in patients with acute coronary syndrome.2009
- Author(s)
  Hirano M, Nakamura T, Kitta Y, Yano T, Kobayashi T, Sano K, Fujioka D, Saito Y, Kodama Y, Kawabata K, Nakamura K, Obata JE, Kugiyama K.
- Journal Title
  
  Atherosclerosis. 203,2
  
  Pages: 483-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390209
[Journal Article] Persistent impairment of endothelial vasomotor function has a negative impact on outcome in patients with coronary artery disease.2009
- Author(s)
  Kitta Y, Obata JE, Nakamura T, Hirano M, Kodama Y, Fujioka D, Saito Y, Kawabata K, Sano K, Kobayashi T, Yano T, Nakamura K, Kugiyama K.
- Journal Title
  
  J Am Coll Cardiol. 53,4
  
  Pages: 323-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390209
[Journal Article] High serum levels of remnant lipoproteins predict ischemic stroke in patients with metabolic syndrome and mild carotid atherosclerosis.2009
- Author(s)
  Nakamura T, Obata JE, Takano H, Kawabata K, Sano K, Kobayashi T, Fujioka D, Saito Y, Yano T, Kugiyama K.
- Journal Title
  
  Atherosclerosis. 202,1
  
  Pages: 234-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390209
[Journal Article] Reduction in myocardial ischemia/reperfusion injury in group X secretory phospholipase A2-deficient mice.2008
- Author(s)
  Fujioka D, Saito Y, Kobayashi T, Yano T, Tezuka H, Ishimoto Y, Suzuki N, Yokota Y, Nakamura T, Obata JE, Kanazawa M, Kawabata K, Hanasaki K, Kugiyama K.
- Journal Title
  
  Circulation. 117,23
  
  Pages: 2977-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390209
[Journal Article] Sirolimus-eluting stent implantation aggravates endothelial vasomotor dysfunction in the infarct-related coronary artery in patients with acute myocardial infarction.2007
- Author(s)
  Obata JE, Kitta Y, Takano H, Kodama Y, Nakamura T, Mende A, Kawabata K, Saitoh Y, Fujioka D, Kobayashi T, Yano T, Kugiyama K.
- Journal Title
  
  J Am Coll Cardiol. 50,14
  
  Pages: 1305-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390209
[Journal Article] Statin reverses reduction of adiponectin receptor expression in infarcted heart and in TNFα-treated cardiomyocytes in association with improved glucose uptake.2007
- Author(s)
  Saito Y, Kugiyama K, et. al.
- Journal Title
  
  Am J Physiol Heart Circ Physiol. 293(6)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390209
[Presentation] Chronic Depletion of GlutathioneExacerbates Ventricular Remodeling andDysfunction in Pressure Overloaded Heartin Mice Lacking the Glutamate-CysteineLigase Modifier Subunit2012
- Author(s)
  Yosuke Watanabe,Kazuhiro Watanabe, Tsuyoshi Kobayashi,Yukio Saito, Daisuke Fujioka, TakamitsuNakamura, Jun-ei Obata, Kenichi Kawabata,Hideto Mishina, and Kiyotaka Kugiyama
- Organizer
  米国心臓病学会
- Place of Presentation
  ロサンゼルス、アメリカ
- Data Source
  KAKENHI-PROJECT-22390158
[Presentation] Group X Secretory Phospholipase A2 inNeutrophils Plays a Pathogenic Role inAbdominal Aortic Aneurysms in Mice2011
- Author(s)
  Kazuhiro Watanabe, Daisuke Fujioka, YukioSaito, Takamitsu Nakamura, Jun-ei Obata,Kenichi Kawabata, Yosuke Watanabe, HidetoMishina, Shun Tamaru, and KiyotakaKugiyama
- Organizer
  米国心臓病学会
- Place of Presentation
  オーランド、アメリカ
- Data Source
  KAKENHI-PROJECT-22390158
[Presentation] Group V Secretory Phospholipase A2Plays a Role in Myocardial IschemiaReperfusion Injury Through CytosolicPhospholipase A22010
- Author(s)
  Toshiaki Yano, KenichiKawabata, Yukio Saito, Kazuhiro Watanabe,Yosuke Watanabe, Hideto Mishina, ShunTamaru, Junei Obata, and Kiyotaka Kugiyama
- Organizer
  米国心臓病学会
- Place of Presentation
  シカゴ、アメリカ
- Data Source
  KAKENHI-PROJECT-22390158
[Presentation] Reduction in Myocardial Ischemia-reperfusion Injury in Group IV Cytosolic Phospholipase A2-deficient Mice Partly Due to Inhibition of TNFα-mediated Pathway to Cell Injury.2009
- Author(s)
  Yukio Saito; Yousuke Watanabe; Hideto Mishina; Kazuhiro Watanabe; Toshiaki Yano; Tsuyoshi Kobayashi; Jun-ei Obata; Ken-ichi Kawabata; Takao Shimizu; Kiyotaka Kugiyama
- Organizer
  American Heart Association Scientific Sessions.
- Place of Presentation
  Orlando.
- Data Source
  KAKENHI-PROJECT-19390209
[Presentation] Reduction in Myocardial Ischemia-reperfusion Injury in Group V Secretory Phospholipase A2-deficient Mice.2009
- Author(s)
  Toshiaki Yano; Keni-chi Kawabata; Yukio Saito; Tsuyoshi Kobayashi; Ryota Sato; Kazuhiro Watanabe; Yosuke Watanabe; Hideto Mishina; Jun-ei Obata; Kiyotaka Kugiyama
- Organizer
  American Heart Association Scientific Sessions.
- Place of Presentation
  Orlando.
- Data Source
  KAKENHI-PROJECT-19390209
[Presentation] Inhibition of Secretory Phospholipase A2 Activity Attenuates Acute Cardiogenic Pulmonary Congestion Induced by Isoproterenol Infusion in Mice with Post-Myocardial Infarction.2008
- Author(s)
  Kenichi Kawabata, Tsuyoshi Kobayashi, Yousuke Watanabe, Kazuhiro Watanabe, Toshiaki Yano, Ryota Sato, Yukio Saito, Kazuto Nakamura, Kiyotaka Kugiyama
- Organizer
  American Heart Association Scientific Sessions
- Place of Presentation
  New Orleans
- Data Source
  KAKENHI-PROJECT-19390209
[Presentation] Group X Secretory Phospholipase A2 has a Critical Role in Neutrophils Activation and Myocardial Ischemia-reperfusion Injury in Mice.2007
- Author(s)
  Daisuke Fujioka, Kenichi Kawabata, Yoshikazu Ishimoto, Noriko Suzuki, Kohji Hansaki, Ryota Sato, Toshiaki Yano, Tsuyoshi Kobayashi, Yukio Saito, Masaki Kanazawa, Kiyotaka Kugiyama
- Organizer
  American Heart Association Scientific Sessions
- Place of Presentation
  Orlando
- Data Source
  KAKENHI-PROJECT-19390209

1. OBATA Jun-ei (60362076)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
2. KUGIYAMA Kiyotaka (00225129)

# of Collaborated Projects: 2 results

# of Collaborated Products: 19 results
3. KAWABATA Kenichi (30345706)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
4. FUJIOKA Daisuke (70377513)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
5. KOBAYASHI Tsuyoshi (40402052)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
6. TEZUKA Hideo (70155456)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. WATANABE Kazuhiro (50535549)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
8. WATANABE Yohsuke (90535551)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
9. MISHINA Hideto (70568021)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
10. YANO Toshiaki (60456449)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. UMETANI Ken

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. OGAWA Ryuji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. ODA Hirotaka

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. ONODERA Tomoya

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. SAKAMOTO Hiroki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. SAWANOBORI Takao

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. TAKAHASHI Minoru

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. TANAKA Hiroyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. NAKAMURA Sunao

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. NAKAMURA Masashi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. HIGUCHI Kotaro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. MATSUMURA Kuniyoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. YAMADA Ayano

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. WATANABE Akinori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SAITO Yukio 齊藤 幸生

斉藤 幸生 サイトウ ユキオ

Research Projects

Research Products

Co-Researchers

long term outcome by reduced impairment of coronary endothelial function after new generation drug-eluting stent implantation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A study of role of phospholipase A2 receptor in pathogenosis ofcardiovascular diseases and development of new drug for cardiovascular diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A study of role of phospholipase A2 in pathogenosis of cardiovascular diseases and development of new drug for cardiovascular diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Chronicdepletion of glutathione exacerbatesventricular remodelling and dysfunctionin the pressure-overloaded heart2013

Author(s)

Journal Title

Data Source

[Journal Article] Group X secretory PLA2 in neutrophilsplays a pathogenic role in abdominalaortic aneurysms in mice2012

Author(s)

Journal Title

Data Source

[Journal Article] Disruption of group IVAcytosolic phospholipase A(2) attenuatesmyocardial ischemia-reperfusion injurypartly through inhibition ofTNF-α-mediated pathway2012

Author(s)

Journal Title

Data Source

[Journal Article] Group V secretoryphospholipase A2 plays a pathogenic rolein myocardial ischaemia-reperfusioninjury2011

Author(s)

Journal Title

Data Source

[Journal Article] Mice lacking the glutamate-cysteine ligase modifier subunit are susceptible to myocardial ischaemia-reperfusion injury.2010

Author(s)

Journal Title

Data Source

[Journal Article] Inhibition of secretory hospholipase A2 activity attenuates lipopolysaccharide-induced acute lung injury in a mouse model.2010

Author(s)

Journal Title

Data Source

[Journal Article] Rapid improvement of carotid plaque echogenicity within 1 month of pioglitazone treatment in patients with acute coronary syndrome.2009

Author(s)

Journal Title

Data Source

[Journal Article] Persistent impairment of endothelial vasomotor function has a negative impact on outcome in patients with coronary artery disease.2009

Author(s)

Journal Title

Data Source

[Journal Article] High serum levels of remnant lipoproteins predict ischemic stroke in patients with metabolic syndrome and mild carotid atherosclerosis.2009

Author(s)

Journal Title

Data Source

[Journal Article] Reduction in myocardial ischemia/reperfusion injury in group X secretory phospholipase A2-deficient mice.2008

Author(s)

Journal Title

Data Source

[Journal Article] Sirolimus-eluting stent implantation aggravates endothelial vasomotor dysfunction in the infarct-related coronary artery in patients with acute myocardial infarction.2007

Author(s)

Journal Title

Data Source

[Journal Article] Statin reverses reduction of adiponectin receptor expression in infarcted heart and in TNFα-treated cardiomyocytes in association with improved glucose uptake.2007

Author(s)

Journal Title

Data Source

[Presentation] Chronic Depletion of GlutathioneExacerbates Ventricular Remodeling andDysfunction in Pressure Overloaded Heartin Mice Lacking the Glutamate-CysteineLigase Modifier Subunit2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Group X Secretory Phospholipase A2 inNeutrophils Plays a Pathogenic Role inAbdominal Aortic Aneurysms in Mice2011

Author(s)

Organizer

Place of Presentation

SAITO Yukio 齊藤幸生

斉藤幸生サイトウユキオ