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Toyohara Jun  豊原 潤

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TOYOHARA Jun  豊原 潤

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Researcher Number 50425659
Other IDs
Affiliation (Current) 2025: 地方独立行政法人東京都健康長寿医療センター, 東京都健康長寿医療センター研究所, 研究部長
Affiliation (based on the past Project Information) *help 2025: 地方独立行政法人東京都健康長寿医療センター, 東京都健康長寿医療センター研究所, 研究部長
2022 – 2024: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究部長
2015 – 2022: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究副部長
2016: 地方独立行政法人東京都健康長寿医療センター, 東京都健康長寿医療センター研究所, 研究副部長
2015: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), その他部局等 … More
2013 – 2015: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), その他部局等, その他
2014: 東京都健康長寿医療センター研究所, 専門副部長
2011 – 2014: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 専門副部長
2013: 東京都健康長寿医療センター研究所, 東京都健康長寿医療センター研究所, 専門副部長
2013: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿長寿医療センター研究所, 専門副部長
2011: 東京都健康長寿医療センター, 東京都健康長寿医療センター研究所, 専門副部長
2010: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究副部長
2007 – 2008: Chiba University, 社会精神保健教育研究センター, 講師 Less
Review Section/Research Field
Principal Investigator
Radiation science / Basic Section 52040:Radiological sciences-related
Except Principal Investigator
Radiation science / Sections That Are Subject to Joint Review: Basic Section47010:Pharmaceutical chemistry and drug development sciences-related , Basic Section47050:Environmental and natural pharmaceutical resources-related / Basic Section 47050:Environmental and natural pharmaceutical resources-related / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Basic Section 52040:Radiological sciences-related / Cerebral neurosurgery
Keywords
Principal Investigator
放射性医薬品 / PET / 核医学 / 薬学 / 癌 / 核酸 / 放射線 / 腫瘍 / 放射性医薬品・造影剤 / 初期臨床試験 … More / 放射性薬剤 / 脳 / アクアポリン / DNA合成 / 神経新生 / 細胞増殖 / フッ素 / 痴呆 / 認知症 / 脳神経疾患 / 分析科学 / がん / 分析化学 / 核医学(PETを含む) / スクレオシド / 分子イメージンヴ / ヌクレオシド / 分子イメージング / ストレス / チミジンホスホリラーゼ / 核医学(PET を含む) … More
Except Principal Investigator
PET / 分子イメージング / C-11 4DST / 11C-4DST / 脳腫瘍 / 核酸誘導体 / ポジトロンCT / 脳神経疾患 / 核医学 / アスタチンー211 / 活性化エステル / ペプチド / ラジオセラノスティクス / テクスチャー解析 / 増殖能評価 / 悪性リンパ腫 / 膠芽腫 / テクスチャ解析 / 低酸素環境 / 腫瘍増殖能 / 癌 / 加速器 / BNCT / BNCT / アポトーシス / 乳癌 / 膵臓癌 / ホウ素中性子捕捉療法 / F-18 FDG / 頭頸部癌 / 低酸素状態 / 低酸素 / F-18 FLT / 核酸代謝 / F-18 FMISO / アデノシンA2受容体 / カフェイン / 加齢 / ノウリアスト / パーキンソン病 / 初期臨床試験 / アデノシンA2A受容体 / 被曝線量 / 神経変性疾患 / グルタミン酸受容体 / 消化器癌 / 4DST / チオチミジン / DNA合成 / 転移性脳腫瘍 / 悪性グリオーマ / thiotymidine / DNA / inflamation / inflammation / methionine / thiothymidine / glioblastoma / glioma Less
  • Research Projects

    (18 results)
  • Research Products

    (357 results)
  • Co-Researchers

    (48 People)
  •  Development of an Efficient Synthesis Method for 18F-Labeled Peptides for a 211At/18F Theranostic Pair"

    • Principal Investigator
      田中 浩士
    • Project Period (FY)
      2025 – 2028
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
      Basic Section 47050:Environmental and natural pharmaceutical resources-related
      Sections That Are Subject to Joint Review: Basic Section47010:Pharmaceutical chemistry and drug development sciences-related , Basic Section47050:Environmental and natural pharmaceutical resources-related
    • Research Institution
      Juntendo University
  •  新規脳内HDAC6イメージング剤のファーストインヒューマン研究Principal Investigator

    • Principal Investigator
      豊原 潤
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
  •  Implementation of high-quality PET ligands with high sensitivity and selectivity for AQP4Principal Investigator

    • Principal Investigator
      Toyohara Jun
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
  •  PET brain research by applying texture analysis to proliferation and hypoxia imaging

    • Principal Investigator
      YAMAMOTO Yuka
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Kagawa University
  •  Development of PET tracer for neurogenesin in the brain based on DNA synthesis imagingPrincipal Investigator

    • Principal Investigator
      Toyohara Jun
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
  •  Molecular imaging of adenosine A2A receptor: a first-in-human study

    • Principal Investigator
      ISHIWATA KIICHI
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      Southen Tohoku Research Institute for Neuroscience
  •  Brain tumor PET research using proliferation and hypoxic imaging

    • Principal Investigator
      Yamamoto Yuka
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Kagawa University
  •  PET molecular imaging of proliferation in head and neck cancer

    • Principal Investigator
      Nishiyama Yoshihiro
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Kagawa University
  •  Molecular imaging of gastrointestinal cancer with PET proliferation tracer

    • Principal Investigator
      Ono Yuko
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Kagawa University
  •  Research on overcoming intractable cancers using hospital-equipped BNCT

    • Principal Investigator
      FUKUMITSU Nobuyoshi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      University of Tsukuba
  •  Development of fluorine-18 labeled 4DST derivatives for clinical usePrincipal Investigator

    • Principal Investigator
      Toyohara Jun
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
  •  Molecular imaging of brain tumor with PET proliferation tracer

    • Principal Investigator
      Yamamoto Yuka
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Kagawa University
  •  Molecular imaging of metablotropic glutamate receptor type 1 – a first-in-human study

    • Principal Investigator
      ISHIWATA Kiichi
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
  •  Molecular imaging of DNA synthesis rate of malignant brain tumor using newly developed positron labelled pharmaceutical.

    • Principal Investigator
      NARIAI Tadashi
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Tokyo Medical and Dental University
  •  Development of PET molecular probes for imaging alpha-synuclein in the brainPrincipal Investigator

    • Principal Investigator
      TOYOHARA Jun
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Radiation science
    • Research Institution
      Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
  •  Development of cancer diagnosis method based on the quantitative measurement of DNA synthesis rate by means of positron emission tomography.Principal Investigator

    • Principal Investigator
      TOYOHARA Jun
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
  •  Organization of PET brain bank

    • Principal Investigator
      ISHIWATA Kiichi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      Tokyo Metropolitan Institute of Gerontology
  •  Development of tumor imaging agent which assumed stress responsea targetPrincipal Investigator

    • Principal Investigator
      TOYOHARA Jun
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Chiba University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation Book

  • [Book] PET and SPECT of Neurobiological Systems2014

    • Author(s)
      Toyohara J, Sakata M and Ishiwata K
    • Total Pages
      600
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Book] Use of (11)C-4DST-PET for Imaging Human Brain Tumors.2014

    • Author(s)
      Nariai, T Inaji, M Sakata, M Toyohara, J.
    • Total Pages
      8
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-23390344
  • [Book] Tumors of the Central Nervous System2013

    • Author(s)
      Nariai T, Inaji M, Sakata M and Toyohara J
    • Total Pages
      500
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Book] Trends on the role of PET in drug development2012

    • Author(s)
      Toyohara, J. and Ishiwata, K.
    • Total Pages
      768
    • Publisher
      World Scientific Publishing Co.
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Book] Trends on the role of PET in drug development 7682012

    • Author(s)
      Toyohara, J. and Ishiwata, K.
    • Publisher
      World Scientific Publishing Co.
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Book] Animal models-Overview of animal models for tumors, brain diseases and genetics. In : Trends on the role of PET in drug development(Elsinga, P.H., van Waarde, A., Paans, A.M.J.and Dierckx, R.A., eds.)2012

    • Author(s)
      Toyohara J, et al
    • Publisher
      World Scientific Publishing Co, Singapore
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Book] Trends on the role of PET in drug development2012

    • Author(s)
      Toyohara, J. and Ishiwata, K
    • Publisher
      World scientific publishing Co
    • Data Source
      KAKENHI-PROJECT-23659605
  • [Book] Trends on the role of PET in drug development2012

    • Author(s)
      Toyohara, J. and Ishiwata, K.
    • Total Pages
      768
    • Publisher
      World scientific publishing Co.
    • Data Source
      KAKENHI-PROJECT-23659605
  • [Book] Springer Verlag, PET and SPECT for neurobiological systems

    • Author(s)
      Toyohara, J., Sakata, M. and Ishiwata, K.
    • Publisher
      (in press)
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Book] Springer Verlag, Tumors of the central nervous system

    • Author(s)
      Nariai, T., Inaji, M., Sakata, M. and Toyohara, J.
    • Publisher
      (in press)
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Journal Article] Preclinical validation of a novel brain-penetrant PET ligand for visualization of histone deacetylase 6: a potential imaging target for neurodegenerative diseases2024

    • Author(s)
      Tago Tetsuro、Sakata Muneyuki、Kanazawa Masakatsu、Yamamoto Shigeyuki、Ishii Kenji、Toyohara Jun
    • Journal Title

      European Journal of Nuclear Medicine and Molecular Imaging

      Volume: - Issue: 8 Pages: 2193-2203

    • DOI

      10.1007/s00259-024-06666-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K07682, KAKENHI-PROJECT-21K07663
  • [Journal Article] Phantom and clinical evaluation of the Bayesian penalised likelihood reconstruction algorithm Q.Clear without PSF correction in amyloid PET images2024

    • Author(s)
      Wagatsuma Kei、Sakata Muneyuki、Miwa Kenta、Hamano Yumi、Kawakami Hirofumi、Kamitaka Yuto、Yamao Tensho、Miyaji Noriaki、Ishibashi Kenji、Tago Tetsuro、Toyohara Jun、Ishii Kenji
    • Journal Title

      EJNMMI Physics

      Volume: 11 Issue: 1

    • DOI

      10.1186/s40658-024-00641-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Journal Article] Pitfalls of Amyloid-Beta PET2024

    • Author(s)
      Ishibashi Kenji、Kurihara Masanori、Toyohara Jun、Ishii Kenji、Iwata Atsushi
    • Journal Title

      Clinical Nuclear Medicine

      Volume: 49 Issue: 4 Pages: 319-321

    • DOI

      10.1097/rlu.0000000000005097

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K14789, KAKENHI-PROJECT-21K07663
  • [Journal Article] A gold-complex initiated functionalization of biologically active polyphenols applied to a <sup>18</sup>F-labeled chemical probe2023

    • Author(s)
      Liu Ziyun、Fukagawa Yuki、Yamano Masaharu、Tago Tetsuro、Iwai Kumiko、Hirano Keiichi、Kumazoe Motofumi、Tachibana Hirofumi、Toyohara Jun、Tanaka Hiroshi
    • Journal Title

      Organic &amp; Biomolecular Chemistry

      Volume: 21 Issue: 29 Pages: 5990-5996

    • DOI

      10.1039/d3ob00856h

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Journal Article] Reversal of spatial memory impairment by phosphodiesterase 3 inhibitor cilostazol is associated with reduced neuroinflammation and increased cerebral glucose uptake in aged male mice2022

    • Author(s)
      Yanai Shuichi、Tago Tetsuro、Toyohara Jun、Arasaki Tomoko、Endo Shogo
    • Journal Title

      Frontiers in Pharmacology

      Volume: 13 Pages: 1031637-1031637

    • DOI

      10.3389/fphar.2022.1031637

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07663, KAKENHI-PROJECT-22K11872, KAKENHI-PROJECT-19H04044, KAKENHI-PROJECT-21K19752
  • [Journal Article] Highlight selection of radiochemistry and radiopharmacy developments by editorial board2022

    • Author(s)
      Toyohara Jun、Al-Qahtani Mohammed、Huang Ya-Yao、Cazzola Emiliano、Todde Sergio、Furumoto Shozo、Mikolajczak Renata、Decristoforo Clemens、Gillings Nic、Yang Min、Reilly Raymond、Duatti Adriano、Denkova Antonia、Schirrmacher Ralf、Carlucci Giuseppe、Seimbille Yann、Liu Zhaofei、Ellis Beverley、Cornelissen Bart T、他2名
    • Journal Title

      EJNMMI Radiopharmacy and Chemistry

      Volume: 7 Issue: 1

    • DOI

      10.1186/s41181-022-00177-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Journal Article] Possibility of Enlargement in Left Medial Temporal Areas Against Cerebral Amyloid Deposition Observed During Preclinical Stage2022

    • Author(s)
      Imabayashi Etsuko、Ishii Kenji、Toyohara Jun、Wagatsuma Kei、Sakata Muneyuki、Tago Tetsuro、Ishibashi Kenji、Kojima Narumi、Kohda Noriyuki、Tokumaru Aya M.、Kim Hunkyung
    • Journal Title

      Frontiers in Aging Neuroscience

      Volume: 14

    • DOI

      10.3389/fnagi.2022.847094

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07663, KAKENHI-PROJECT-20K16747
  • [Journal Article] Adenosine A2A Receptor Occupancy by Caffeine After Coffee Intake in Parkinson's Disease2022

    • Author(s)
      Ishibashi Kenji、Miura Yoshiharu、Wagatsuma Kei、Toyohara Jun、Ishiwata Kiichi、Ishii Kenji
    • Journal Title

      Movement Disorders

      Volume: 37 Issue: 4 Pages: 853-857

    • DOI

      10.1002/mds.28897

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K07663, KAKENHI-PROJECT-20K16747
  • [Journal Article] Determination of optimal regularization factor in Bayesian penalized likelihood reconstruction of brain PET images using [18F]FDG and [11C]PiB2022

    • Author(s)
      Wagatsuma Kei、Miwa Kenta、Kamitaka Yuto、Koike Emiya、Yamao Tensho、Yoshii Tokiya、Kobayashi Rinya、Nezu Shogo、Sugamata Yuta、Miyaji Noriaki、Imabayashi Etsuko、Ishibashi Kenji、Toyohara Jun、Ishii Kenji
    • Journal Title

      Medical Physics

      Volume: - Issue: 5 Pages: 2995-3005

    • DOI

      10.1002/mp.15593

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K07663, KAKENHI-PROJECT-22K18234, KAKENHI-PROJECT-20K16747
  • [Journal Article] Radiosynthesis and <i>in Vivo</i> and <i>ex Vivo</i> Evaluation of Isomeric [<sup>11</sup>C]methoxy Analogs of Nimesulide as Brain Cyclooxygenase-2-Targeted Imaging Agents2022

    • Author(s)
      Yamamoto Yumi、Tago Tetsuro、Toyohara Jun、Saito Yohei、Yamamoto Fumihiko
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 45 Issue: 1 Pages: 94-103

    • DOI

      10.1248/bpb.b21-00608

    • NAID

      130008139158

    • ISSN
      0918-6158, 1347-5215
    • Year and Date
      2022-01-01
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08088, KAKENHI-PROJECT-20K08117, KAKENHI-PROJECT-21K07663
  • [Journal Article] Distribution Pattern of the Monoamine Oxidase B Ligand, 18F-THK5351, in the Healthy Brain2022

    • Author(s)
      Ishibashi Kenji、Miura Yoshiharu、Tago Tetsuro、Toyohara Jun、Higashihara Mana、Iwata Atsushi、Ishii Kenji
    • Journal Title

      Clinical Nuclear Medicine

      Volume: 47 Issue: 7 Pages: e489-e495

    • DOI

      10.1097/rlu.0000000000004272

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07663, KAKENHI-PROJECT-19K08191
  • [Journal Article] First clinical assessment of [18F]MC225, a novel fluorine-18 labelled PET tracer for measuring functional P-glycoprotein at the blood-brain barrier2021

    • Author(s)
      Toyohara Jun、Sakata Muneyuki、Ishibashi Kenji、Mossel Pascalle、Imai Masamichi、Wagatsuma Kei、Tago Tetsuro、Imabayashi Etsuko、Colabufo Nicola A.、Luurtsema Gert、Ishii Kenji
    • Journal Title

      Annals of Nuclear Medicine

      Volume: 35 Issue: 11 Pages: 1240-1252

    • DOI

      10.1007/s12149-021-01666-9

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Journal Article] Automated production of [18F]MK-6240 on CFN-MPS2002021

    • Author(s)
      Toyohara Jun、Nishino Kosuke、Sakai Masanari、Tago Tetsuro、Oda Takashi
    • Journal Title

      Applied Radiation and Isotopes

      Volume: 168 Pages: 109468-109468

    • DOI

      10.1016/j.apradiso.2020.109468

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Journal Article] Highlight selection of radiochemistry and radiopharmacy developments by editorial board (January-June 2020)2021

    • Author(s)
      Al-Qahtani Mohammed、Behe Martin、Bormans Guy、Carlucci Giuseppe、Dasilva Jean、Decristoforo Clemens、Elsinga Philip H.、Kopka Klaus、Li Xiang-Guo、Mach Robert、Middel Oskar、Passchier Jan、Patt Marianne、Penuelas Ivan、Rey Ana、Scott Peter J. H.、Todde Sergio、Toyohara Jun、Vugts Danielle
    • Journal Title

      EJNMMI Radiopharmacy and Chemistry

      Volume: 6 Issue: 1

    • DOI

      10.1186/s41181-020-00118-5

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Journal Article] Efficacy of cell proliferation imaging with 4DST PET/CT for predicting the prognosis of patients with esophageal cancer: a comparison study with FDG PET/CT2021

    • Author(s)
      Hotta Masatoshi、Minamimoto Ryogo、Toyohara Jun、Nohara Kyoko、Nakajima Kazuhiko、Takase Kei、Yamada Kazuhiko
    • Journal Title

      European Journal of Nuclear Medicine and Molecular Imaging

      Volume: 48 Issue: 8 Pages: 2615-2623

    • DOI

      10.1007/s00259-020-05179-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07658, KAKENHI-PROJECT-21K07663
  • [Journal Article] Correlation of 4'-[methyl-11C]-thiothymidine PET with Ki-67 immunohistochemistry separately in patients with newly diagnosed and recurrent gliomas.2021

    • Author(s)
      Norikane T, Mitamura K, Yamamoto Y, Hatakeyama T, Miyake K, Toyohara J, Nishiyama Y.
    • Journal Title

      Nucl Med Commun.

      Volume: 42 Issue: 12 Pages: 1322-1327

    • DOI

      10.1097/mnm.0000000000001463

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08099, KAKENHI-PROJECT-21K07663
  • [Journal Article] Preclinical Evaluation of an 18F-Labeled SW-100 Derivative for PET Imaging of Histone Deacetylase 6 in the Brain2021

    • Author(s)
      Tago Tetsuro、Toyohara Jun、Ishii Kenji
    • Journal Title

      ACS Chemical Neuroscience

      Volume: 12 Issue: 4 Pages: 746-755

    • DOI

      10.1021/acschemneuro.0c00774

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K16778, KAKENHI-PROJECT-18K07658
  • [Journal Article] Highlight selection of radiochemistry and radiopharmacy developments by editorial board2021

    • Author(s)
      Aime S.、Al-Qahtani M.、Behe M.、Bormans G.、Carlucci G.、DaSilva J. N.、Decristoforo C.、Duatti A.、Elsinga P. H.、Kopka K.、Li X.-G.、Liu Z.、Mach R. H.、Middel O.、Passchier J.、Patt M.、Penuelas I.、Rey A.、Scott P. J. H.、Todde S.、Toyohara J.、Vugts D.、Yang Z.
    • Journal Title

      EJNMMI Radiopharmacy and Chemistry

      Volume: 6 Issue: 1

    • DOI

      10.1186/s41181-021-00128-x

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Journal Article] Head-to-head comparison of the two MAO-B radioligands, 18F-THK5351 and 11C-L-Deprenyl, to visualize astrogliosis in patients with neurological disorders2021

    • Author(s)
      Kenji Ishibashi, Masashi Kameyama, Yoshiharu Miura, Jun Toyohara, Kenji Ishii
    • Journal Title

      Clinical Nuclear Medicine

      Volume: 46 Issue: 1 Pages: e31-e33

    • DOI

      10.1097/rlu.0000000000003197

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08191, KAKENHI-PROJECT-18K07488, KAKENHI-PROJECT-18K07658
  • [Journal Article] N-Alkyl 3‐aminobut‐2‐enenitrile as a Non‐radioactive Side Product in Nucleophilic 18F‐Fluorination2021

    • Author(s)
      Song Ruichong、Tago Tetsuro、Tatsuta Maho、Shiraishi Nana、Iwai Kumiko、Hirano Keiichi、Toyohara Jun、Tanaka Hiroshi
    • Journal Title

      ChemistrySelect

      Volume: 6 Issue: 12 Pages: 2826-2831

    • DOI

      10.1002/slct.202100723

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Journal Article] Correlation of 4′-[methyl-11C]-thiothymidine PET with Gd-enhanced and FLAIR MRI in patients with newly diagnosed glioma2021

    • Author(s)
      Norikane Takashi、Mitamura Katsuya、Yamamoto Yuka、Maeda Yukito、Tanaka Kenichi、Hatakeyama Tetsuhiro、Miyake Keisuke、Toyohara Jun、Nishiyama Yoshihiro
    • Journal Title

      EJNMMI Research

      Volume: 11 Issue: 1 Pages: 42-42

    • DOI

      10.1186/s13550-021-00785-8

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658, KAKENHI-PROJECT-19K08099, KAKENHI-PROJECT-21K07663
  • [Journal Article] Head-to-head comparison of (R)-[11C]verapamil and [18F]MC225 in non-human primates, tracers for measuring P-glycoprotein function2021

    • Author(s)
      Garcia-Varela Lara、Vallez Garcia David、Aguiar Pablo、Kakiuchi Takeharu、Ohba Hiroyuki、Harada Norihiro、Nishiyama Shingo、Tago Tetsuro、Elsinga Philip H.、Tsukada Hideo、Colabufo Nicola A.、Dierckx Rudi A. J. O.、van Waarde Aren、Toyohara Jun、Boellaard Ronald、Luurtsema Gert
    • Journal Title

      European Journal of Nuclear Medicine and Molecular Imaging

      Volume: 48 Issue: 13 Pages: 4307-4317

    • DOI

      10.1007/s00259-021-05411-2

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Journal Article] Test-retest reproducibility of cerebral adenosine A2A receptor quantification using [11C]preladenant2021

    • Author(s)
      Toyohara Jun、Sakata Muneyuki、Wagatsuma Kei、Tago Tetsuro、Ishibashi Kenji、Ishii Kenji、Elsinga Philip、Ishiwata Kiichi
    • Journal Title

      Annals of Nuclear Medicine

      Volume: 36 Issue: 1 Pages: 15-23

    • DOI

      10.1007/s12149-021-01678-5

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Journal Article] Effects of 18F-fluorinated neopentyl glycol side-chain on the biological characteristics of stilbene amyloid-β PET ligands2021

    • Author(s)
      Tago Tetsuro、Toyohara Jun、Fujimaki Ryo、Tatsuta Maho、Song Ruichong、Hirano Keiichi、Iwai Kumiko、Tanaka Hiroshi
    • Journal Title

      Nuclear Medicine and Biology

      Volume: 94-95 Pages: 38-45

    • DOI

      10.1016/j.nucmedbio.2020.12.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Journal Article] Evaluation of P-glycoprotein function at the blood-brain barrier using [18F]MC225-PET2021

    • Author(s)
      Mossel Pascalle、Garcia Varela Lara、Arif Wejdan M.、van der Weijden Chris W. J.、Boersma Hendrikus H.、Willemsen Antoon T. M.、Boellaard Ronald、Elsinga Philip H.、Borra Ronald J. H.、Colabufo Nicola A.、Toyohara Jun、de Deyn Peter Paul、Dierckx Rudi A. J. O.、Lammertsma Adriaan A.、Bartels Anna L.、Luurtsema Gert
    • Journal Title

      European Journal of Nuclear Medicine and Molecular Imaging

      Volume: 48 Issue: 12 Pages: 4105-4106

    • DOI

      10.1007/s00259-021-05419-8

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Journal Article] Interim 4′-[methyl-11C]-thiothymidine PET for predicting the chemoradiotherapeutic response in head and neck squamous cell carcinoma: comparison with [18F]FDG PET2021

    • Author(s)
      Mitamura Katsuya、Norikane Takashi、Yamamoto Yuka、Fujimoto Kengo、Takami Yasukage、Hoshikawa Hiroshi、Toyohara Jun、Nishiyama Yoshihiro
    • Journal Title

      EJNMMI Research

      Volume: 11 Issue: 1

    • DOI

      10.1186/s13550-021-00749-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Journal Article] Mechanical regulation underlies effects of exercise on serotonin-induced signaling in the prefrontal cortex neurons.2020

    • Author(s)
      Ryu Y, Maekawa T, Yoshino D, Sakitani N, Takashima A, Inoue T, Suzurikawa J, Toyohara J, Tago T, Fujita N, Sawada K, Murase S, Watanave M, Sakai T, Yoshikawa Y, Ogata T, Shinohara M, Nagao M, Sawada Y
    • Journal Title

      iScience

      Volume: 23 Issue: 2 Pages: 100874-100874

    • DOI

      10.1016/j.isci.2020.100874

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18KT0018, KAKENHI-PROJECT-18K07658, KAKENHI-PLANNED-17H06380, KAKENHI-PROJECT-18H04088, KAKENHI-PROJECT-18H02027, KAKENHI-PROJECT-19H03124, KAKENHI-PROJECT-18K15655
  • [Journal Article] Voxel-based morphometry focusing on medial temporal lobe structures has a limited capability to detect amyloid β, an Alzheimer’s disease pathology2020

    • Author(s)
      Kameyama Masashi、Ishibashi Kenji、Toyohara Jun、Wagatsuma Kei、Umeda-Kameyama Yumi,、Shimoji Keigo、Kanemaru Kazutomi、Murayama Shigeo、Ogawa Sumito、Tokumaru Aya M.、Ishii Kenji
    • Journal Title

      Aging

      Volume: 12 Issue: 19 Pages: 19701-19710

    • DOI

      10.18632/aging.104012

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07488, KAKENHI-PROJECT-18K07658
  • [Journal Article] Development of PET radiopharmaceuticals at the Tokyo Metropolitan Institute of Gerontology2020

    • Author(s)
      Jun Toyohara
    • Journal Title

      Annals of Nuclear Medicine and Molecular Imaging

      Volume: 33 Pages: 137-150

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Journal Article] Synthesis and evaluation of N-isopropyl-p-[11C]methylamphetamine as a novel cerebral blood flow tracer for positron emission tomography2020

    • Author(s)
      Toyohara Jun、Harada Norihiro、Kakiuchi Takeharu、Ohba Hiroyuki、Kanazawa Masakatsu、Tago Tetsuro、Sakata Muneyuki、Ishiwata Kiichi
    • Journal Title

      EJNMMI Research

      Volume: 10 Issue: 1

    • DOI

      10.1186/s13550-020-00702-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Journal Article] Metabolic network topology of Alzheimer’s disease and dementia with Lewy bodies generated using fluorodeoxyglucose positron emission tomography.2020

    • Author(s)
      Imai M, Tanaka M, SakataM, Wagatsuma K, Tago T, Toyohara J, Sengoku R, Nishina Y, Kanemaru K, Ishibashi K, Murayama S, Ishii K.
    • Journal Title

      J Alzheimers Dis

      Volume: 73 Issue: 1 Pages: 197-207

    • DOI

      10.3233/jad-190843

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09736, KAKENHI-PROJECT-18K07658, KAKENHI-PROJECT-17K09813, KAKENHI-PROJECT-18K15655
  • [Journal Article] Pharmacokinetic Modeling of [18F]MC225 for Quantification of the P-Glycoprotein Function at the Blood-Brain Barrier in Non-Human Primates with PET2020

    • Author(s)
      Garcia-Varela Lara、Arif Wejdan M.、Vallez Garcia David、Kakiuchi Takeharu、Ohba Hiroyuki、Harada Norihiro、Tago Tetsuro、Elsinga Philip H.、Tsukada Hideo、Colabufo Nicola Antonio、Dierckx Rudi A. J. O.、van Waarde Aren、Toyohara Jun、Boellaard Ronald、Luurtsema Gert
    • Journal Title

      Molecular Pharmaceutics

      Volume: 17 Issue: 9 Pages: 3477-3486

    • DOI

      10.1021/acs.molpharmaceut.0c00514

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Journal Article] Automated synthesis, preclinical toxicity, and radiation dosimetry of [18F]MC225 for clinical use: a tracer for measuring P-glycoprotein function at the blood-brain barrier2020

    • Author(s)
      Toyohara Jun、Sakata Muneyuki、Tago Tetsuro、Colabufo Nicola A.、Luurtsema Gert
    • Journal Title

      EJNMMI Research

      Volume: 10 Issue: 1

    • DOI

      10.1186/s13550-020-00674-6

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Journal Article] Texture indices of 4′-[methyl-11C]-thiothymidine uptake predict p16 status in patients with newly diagnosed oropharyngeal squamous cell carcinoma: comparison with 18F-FDG uptake2020

    • Author(s)
      Ihara-Nishishita Ayumi、Norikane Takashi、Mitamura Katsuya、Yamamoto Yuka、Fujimoto Kengo、Takami Yasukage、Ibuki Emi、Kudomi Nobuyuki、Hoshikawa Hiroshi、Toyohara Jun、Nishiyama Yoshihiro
    • Journal Title

      European Journal of Hybrid Imaging

      Volume: 4 Issue: 1

    • DOI

      10.1186/s41824-020-00090-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Journal Article] Pharmacokinetic Modeling of (R)-[11C]verapamil to Measure the P-Glycoprotein Function in Nonhuman Primates2020

    • Author(s)
      Garcia-Varela Lara、Garcia David Vallez、Kakiuchi Takeharu、Ohba Hiroyuki、Nishiyama Shingo、Tago Tetsuro、Elsinga Philip H.、Tsukada Hideo、Colabufo Nicola A.、Dierckx Rudi A.J.O.、van Waarde Aren、Toyohara Jun、Boellaard Ronald、Luurtsema Gert
    • Journal Title

      Molecular Pharmaceutics

      Volume: 18 Issue: 1 Pages: 416-428

    • DOI

      10.1021/acs.molpharmaceut.0c01014

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Journal Article] 18F-THK5351 PET Can Identify Astrogliosis in Multiple Sclerosis Plaques2020

    • Author(s)
      Ishibashi Kenji、Miura Yoshiharu、Hirata Kosei、Toyohara Jun、Ishii Kenji
    • Journal Title

      Clinical Nuclear Medicine

      Volume: 45 Issue: 2 Pages: e98-e100

    • DOI

      10.1097/rlu.0000000000002751

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658, KAKENHI-PROJECT-19K08191, KAKENHI-PROJECT-17K09813
  • [Journal Article] Adenosine A2A Receptor Occupancy by Long‐Term Istradefylline Administration in Parkinson's Disease2020

    • Author(s)
      Ishibashi Kenji、Miura Yoshiharu、Wagatsuma Kei、Toyohara Jun、Ishiwata Kiichi、Ishii Kenji
    • Journal Title

      Movement Disorders

      Volume: 36 Issue: 1 Pages: 268-269

    • DOI

      10.1002/mds.28378

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Journal Article] Radiosynthesis and preliminary evaluation of an 18F-labeled tubastatin A analog for PET imaging of histone deacetylase 62020

    • Author(s)
      Tago Tetsuro、Toyohara Jun、Ishii Kenji
    • Journal Title

      Journal of Labelled Compounds and Radiopharmaceuticals

      Volume: 63 Issue: 2 Pages: 85-95

    • DOI

      10.1002/jlcr.3823

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07658, KAKENHI-PROJECT-18K15655
  • [Journal Article] Relationship between the temporal course of astrogliosis and symptom improvement in cerebral infarction: report of a case monitored using 18 F-THK5351 positron emission tomography2020

    • Author(s)
      Kenji Ishibashi, Yoshiharu Miura, Kosei Hirata, Jun Toyohara, Kenji Ishii
    • Journal Title

      BMC Medical Imaging

      Volume: 20 Issue: 1 Pages: 81-81

    • DOI

      10.1186/s12880-020-00481-4

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08191, KAKENHI-PROJECT-18K07658
  • [Journal Article] パーキンソン病におけるアデノシンA2A受容体の病態解析2020

    • Author(s)
      石橋賢士、多胡哲郎、我妻慧、坂田宗之、豊原潤、石井賢二
    • Journal Title

      臨床薬理の進歩

      Volume: 41 Pages: 15-23

    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Journal Article] 18F-FDG and 11C-4DST PET/CT for evaluating response to platinum-based doublet chemotherapy in advanced non-small cell lung cancer: a prospective study2019

    • Author(s)
      Minamimoto Ryogo、Takeda Yuichiro、Hotta Masatoshi、Toyohara Jun、Nakajima Kazuhiko、Naka Go、Sugiyama Haruhito
    • Journal Title

      EJNMMI Research

      Volume: 9 Issue: 1 Pages: 4-4

    • DOI

      10.1186/s13550-019-0472-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Journal Article] Monoamine Oxidase B Binding of 18F-THK5351 to Visualize Glioblastoma and Associated Gliosis2019

    • Author(s)
      Tago Tetsuro、Toyohara Jun、Sengoku Renpei、Murayama Shigeo、Ishii Kenji
    • Journal Title

      Clinical Nuclear Medicine

      Volume: 44 Issue: 6 Pages: 507-509

    • DOI

      10.1097/rlu.0000000000002564

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09813, KAKENHI-PROJECT-18K15655, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16K09736, KAKENHI-PROJECT-18K07658
  • [Journal Article] Pre‐discard estimation of radioactivated materials in positron emission tomography cyclotron systems and concrete walls of a cyclotron vault2019

    • Author(s)
      Wagatsuma Kei、Ishiwata Kiichi、Nobuhara Fumiyoshi、Koumura Iwane、Kunugi Masayuki、Oda Keiichi、Miwa Kenta、Toyohara Jun、Ishii Kenji
    • Journal Title

      Medical Physics

      Volume: 46 Issue: 5 Pages: 2457-2467

    • DOI

      10.1002/mp.13492

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07658, KAKENHI-PROJECT-16K19831
  • [Journal Article] A pitfall of white matter reference regions used in [18F] florbetapir PET: a consideration of kinetics2019

    • Author(s)
      Kameyama M, Ishibash K, Wagatsuma K, Toyohara J, Ishii K
    • Journal Title

      Ann Nucl Med

      Volume: 33 Issue: 11 Pages: 848-854

    • DOI

      10.1007/s12149-019-01397-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07488, KAKENHI-PROJECT-18K07658
  • [Journal Article] Unchanged type 1 metabotropic glutamate receptor availability in patients with Alzheimer's disease: A study using 11C-ITMM positron emission tomography2019

    • Author(s)
      Ishibashi Kenji、Miura Yoshiharu、Toyohara Jun、Ishiwata Kiichi、Ishii Kenji
    • Journal Title

      NeuroImage: Clinical

      Volume: 22 Pages: 101783-101783

    • DOI

      10.1016/j.nicl.2019.101783

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658, KAKENHI-PROJECT-15K19503
  • [Journal Article] Radiosynthesis of 18F-labeled d-allose2019

    • Author(s)
      Yamamoto Hiroyuki、Wada Kenji、Toyohara Jun、Tago Tetsuro、Ibaraki Masanobu、Kinoshita Toshibumi、Yamamoto Yuka、Nishiyama Yoshihiro、Kudomi Nobuyuki
    • Journal Title

      Carbohydrate Research

      Volume: 486 Pages: 107827-107827

    • DOI

      10.1016/j.carres.2019.107827

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07658, KAKENHI-PROJECT-18K15655
  • [Journal Article] 4′-[methyl-11C]-thiothymidine as a proliferation imaging tracer for detection of colorectal cancer: comparison with 18F-FDG2019

    • Author(s)
      Fukuda Yuko、Yamamoto Yuka、Mitamura Katsuya、Ishikawa Ryo、Asano Eisuke、Toyohara Jun、Norikane Takashi、Nishiyama Yoshihiro
    • Journal Title

      Annals of Nuclear Medicine

      Volume: 33 Issue: 11 Pages: 822-827

    • DOI

      10.1007/s12149-019-01393-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Journal Article] Characterization of the binding of tau imaging ligands to melanin-containing cells: putative off-target-binding site2019

    • Author(s)
      Tago Tetsuro、Toyohara Jun、Harada Ryuichi、Furumoto Shozo、Okamura Nubuyuki、Kudo Yukitsuka、Takahashi-Fujigasaki Junko、Murayama Shigeo、Ishii Kenji
    • Journal Title

      Annals of Nuclear Medicine

      Volume: 33 Issue: 6 Pages: 1-8

    • DOI

      10.1007/s12149-019-01344-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09813, KAKENHI-PROJECT-18K15655, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18K07658, KAKENHI-PROJECT-18K15538, KAKENHI-PLANNED-26117003, KAKENHI-PROJECT-18H02771
  • [Journal Article] Efficacy of 4′-[methyl-11C] thiothymidine PET/CT before and after neoadjuvant therapy for predicting therapeutic responses in patients with esophageal cancer: a pilot study2019

    • Author(s)
      Hotta Masatoshi、Minamimoto Ryogo、Yamada Kazuhiko、Nohara Kyoko、Soma Daisuke、Nakajima Kazuhiko、Toyohara Jun、Takase Kei
    • Journal Title

      EJNMMI Research

      Volume: 9 Issue: 1 Pages: 10-10

    • DOI

      10.1186/s13550-019-0478-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07658, KAKENHI-PROJECT-17K18396, KAKENHI-PROJECT-17K10618
  • [Journal Article] Searching for diagnostic properties of novel fluorine-18-labeled d-allose2019

    • Author(s)
      Toyohara Jun、Yamamoto Hiroyuki、Tago Tetsuro
    • Journal Title

      Annals of Nuclear Medicine

      Volume: 33 Issue: 11 Pages: 855-865

    • DOI

      10.1007/s12149-019-01398-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07658, KAKENHI-PROJECT-18K15655
  • [Journal Article] Correlation of 4′-[methyl-11C]-thiothymidine uptake with human equilibrative nucleoside transporter-1 and thymidine kinase-1 expressions in patients with newly diagnosed gliomas2018

    • Author(s)
      Takami Yasukage、Yamamoto Yuka、Ueno Masaki、Chiba Yoichi、Norikane Takashi、Hatakeyama Tetsuhiro、Miyake Keisuke、Toyohara Jun、Nishiyama Yoshihiro
    • Journal Title

      Annals of Nuclear Medicine

      Volume: 32 Issue: 9 Pages: 634-641

    • DOI

      10.1007/s12149-018-1285-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07658, KAKENHI-PROJECT-16K10350, KAKENHI-PROJECT-16K10351
  • [Journal Article] Dynamic Exercise Elicits Dissociated Changes Between Tissue Oxygenation and Cerebral Blood Flow in the Prefrontal Cortex: A Study Using NIRS and PET.2018

    • Author(s)
      (12).Hiura, M., Nariai, T., Takahashi, K., Muta, A., Sakata, M., Ishibashi, K., Toyohara, J., Wagatsuma, K., Tago, T., Ishii, K., Maehara, T.
    • Journal Title

      Adv Exp Med Biol. 2018 Aug 30;1072:269-274.

      Volume: 1072 Pages: 269-274

    • DOI

      10.1007/978-3-319-91287-5_43

    • ISBN
      9783319912851, 9783319912875
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K01841, KAKENHI-PROJECT-18K07658
  • [Journal Article] Reliable radiosynthesis of 4-[10B]borono-2-[18F]fluoro-l-phenylalanine with quality assurance for boron neutron capture therapy-oriented diagnosis2018

    • Author(s)
      Ishiwata Kiichi、Ebinuma Ryoichi、Watanabe Chuichi、Hayashi Kunpei、Toyohara Jun
    • Journal Title

      Annals of Nuclear Medicine

      Volume: 32 Issue: 7 Pages: 463-473

    • DOI

      10.1007/s12149-018-1268-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Journal Article] Occupancy of adenosine A2A receptors by istradefylline in patients with Parkinson's disease using 11C-preladenant PET2018

    • Author(s)
      Ishibashi Kenji、Miura Yoshiharu、Wagatsuma Kei、Toyohara Jun、Ishiwata Kiichi、Ishii Kenji
    • Journal Title

      Neuropharmacology

      Volume: 143 Pages: 106-112

    • DOI

      10.1016/j.neuropharm.2018.09.036

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07658, KAKENHI-PROJECT-16H05396
  • [Journal Article] Validation of scatter limitation correction to eliminate scatter correction error in oxygen-15 gas-inhalation positron emission tomography images2018

    • Author(s)
      Wagatsuma Kei、Oda Keiichi、Sakata Muneyuki、Inaji Motoki、Miwa Kenta、Sasaki Masayuki、Toyohara Jun、Ishii Kenji
    • Journal Title

      Nuclear Medicine Communications

      Volume: 39 Issue: 10 Pages: 936-944

    • DOI

      10.1097/mnm.0000000000000882

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07658, KAKENHI-PROJECT-16K19831
  • [Journal Article] Usefulness of <sup>11</sup>C-Methionine Positron Emission Tomography for Monitoring of Treatment Response and Recurrence in a Glioblastoma Patient on Bevacizumab Therapy: A Case Report2018

    • Author(s)
      Nakano Tomoyuki、Tamura Kaoru、Tanaka Yoji、Inaji Motoki、Hayashi Shihori、Kobayashi Daisuke、Nariai Tadashi、Toyohara Jun、Ishii Kenji、Maehara Taketoshi
    • Journal Title

      Case Reports in Oncology

      Volume: 11 Issue: 2 Pages: 442-449

    • DOI

      10.1159/000490457

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07658, KAKENHI-PROJECT-15K19954
  • [Journal Article] Central μ-opioidergic system activation evoked by heavy and severe-intensity cycling exercise in humans: a pilot study using positron emission tomography with 11C-carfentanil.2017

    • Author(s)
      Hiura M, Sakata M, Ishii K, Toyohara J, Oda K, Nariai T, Ishiwata K.
    • Journal Title

      Int. J. Sports Med.

      Volume: 38 Issue: 01 Pages: 19-26

    • DOI

      10.1055/s-0042-114779

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293271, KAKENHI-PROJECT-26670637, KAKENHI-PROJECT-16K01841
  • [Journal Article] Comparison of imaging using 11C-ITMM and 18F-FDG for the detection of cerebellar ataxia.2017

    • Author(s)
      Ishibashi K, Miura Y, Toyohara J, Ishii K, Ishiwata K.
    • Journal Title

      J. Neurol. Sci.

      Volume: 375 Pages: 97-102

    • DOI

      10.1016/j.jns.2017.01.036

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293271, KAKENHI-PROJECT-15K19503
  • [Journal Article] Initial evaluation of a novel adenosine A2A receptor ligand, 11C-preladenant, in healthy human subjects2017

    • Author(s)
      Sakata M, Ishibashi K, Imai M, Wagatsuma K, Ishii K, Zhou X, de Vries EFJ, Elsinga PH, Ishiwata K, Toyohara J.
    • Journal Title

      Journal of Nuclear Medicine

      Volume: 58 Issue: 9 Pages: 1464-1470

    • DOI

      10.2967/jnumed.116.188474

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05396, KAKENHI-PROJECT-25293271
  • [Journal Article] Evaluation of peri-implant bone metabolism under immediate loading using high-resolution Na18F-PET.2017

    • Author(s)
      Matsuo Y, Ogawa T, Yamamoto M, Shibamoto A, Saenz JR, Yokoyama M, Kanda Y, Toyohara J, Sasaki K.
    • Journal Title

      Clin. Oral Investig.

      Volume: 印刷中 Issue: 6 Pages: 2029-2037

    • DOI

      10.1007/s00784-016-1992-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Journal Article] Long-term cilostazol administration ameliorates memory decline in senescence-accelerated mouse prone 8 (SAMP8) through a dual effect on cAMP and blood-brain barrier.2017

    • Author(s)
      Yanai S, Toyohara J, Ishiwata K, Ito H, Endo S.
    • Journal Title

      Neuropharmacology

      Volume: 116 Pages: 246-259

    • DOI

      10.1016/j.neuropharm.2016.12.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293271, KAKENHI-PROJECT-15H03103
  • [Journal Article] Assessment of safety, efficacy, and dosimetry of a novel 18-kDa translocator protein ligand, [11C]CB184, in healthy human volunteers2017

    • Author(s)
      Sakata M, Ishibashi K, Imai M, Wagatsuma K, Ishii K, Hatano K, Ishiwata K, Toyohara J.
    • Journal Title

      EJNMMI Res.

      Volume: 7 Issue: 1 Pages: 26-26

    • DOI

      10.1186/s13550-017-0271-6

    • NAID

      120007134889

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Journal Article] Determination of radionuclides and radiochemical impurities produced by in-house cyclotron irradiation and subsequent radiosynthesis of PET tracers.2017

    • Author(s)
      Ishiwata K, Hayashi K, Sakai M, Kawaguchi S, Hasegawa H, Toyohara J.
    • Journal Title

      Ann. Nucl. Med.

      Volume: 31 Issue: 1 Pages: 84-92

    • DOI

      10.1007/s12149-016-1134-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Journal Article] Synthesis and basic evaluation of 7α-(3-[18F]fluoropropyl)-testosterone and 7α-(3-[18F]fluoropropyl)-dihydrotestosterone.2017

    • Author(s)
      Okamoto M, Naka K, Ishiwata K, Shimizu I, Toyohara J
    • Journal Title

      Ann. Nucl. Med

      Volume: 31 Issue: 1 Pages: 53-62

    • DOI

      10.1007/s12149-016-1130-7

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25293271, KAKENHI-PROJECT-26870647
  • [Journal Article] Age and gender effects of 11C-ITMM binding to metabotropic glutamate receptor type 1 in healthy human participants.2017

    • Author(s)
      Sakata M, Toyohara J, Ishibashi K, Wagatsuma K, Ishii K, Zhang MR, Ishiwata K
    • Journal Title

      Neurobiol Aging.

      Volume: 55 Pages: 72-77

    • DOI

      10.1016/j.neurobiolaging.2017.03.022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293269, KAKENHI-PROJECT-25293271
  • [Journal Article] Optimization of the alkyl side chain length of fluorine-18-labeled 7α-alkyl-fluoroestradiol.2016

    • Author(s)
      Okamoto M, Shibayama H, Naka K, Kitagawa Y, Ishiwata K, Shimizu I, Toyohara J.
    • Journal Title

      Nucl. Med. Biol.

      Volume: 43 Issue: 8 Pages: 512-519

    • DOI

      10.1016/j.nucmedbio.2016.05.008

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25293271, KAKENHI-PROJECT-26870647
  • [Journal Article] Relationship between type 1 metabotropic glutamate receptors and cerebellar ataxia.2016

    • Author(s)
      Ishibashi K, Miura Y, Ishikawa K, Zhang MR, Toyohara J, Ishiwata K, Ishii K.
    • Journal Title

      J Neurol.

      Volume: 263 Issue: 11 Pages: 2179-2187

    • DOI

      10.1007/s00415-016-8248-3

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293269, KAKENHI-PROJECT-25293271, KAKENHI-PROJECT-15K19503
  • [Journal Article] Preclinical and the first-in-man studies on [11C]CB184 for imaging 18 kDa translocator protein by positron emission tomography2016

    • Author(s)
      J.Toyohara, M. Sakata, K. Hatano, S. Yanai, S. Endo, K. Ishibashi, K. Wagatsuma, K. Ishii and K. Ishiwata
    • Journal Title

      Annals of Nuclear Medicine

      Volume: 30 Issue: 8 Pages: 534-543

    • DOI

      10.1007/s12149-016-1094-7

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H03103, KAKENHI-PROJECT-25293271
  • [Journal Article] Correlation of 4′-[methyl-11C]-thiothymidine uptake with Ki-67 immunohistochemistry and tumor grade in patients with newly diagnosed gliomas in comparison with 11C-methionine uptake2016

    • Author(s)
      Kenichi Tanaka, Yuka Yamamoto, Yukito Maeda, Hiroyuki Yamamoto, Nobuyuki Kudomi, Nobuyuki Kawai, Jun Toyohara, Yoshihiro Nishiyama
    • Journal Title

      Annals of Nuclear Medicine

      Volume: 30 Issue: 2 Pages: 89-96

    • DOI

      10.1007/s12149-015-1035-x

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25461828, KAKENHI-PROJECT-25293271, KAKENHI-PROJECT-16K10350
  • [Journal Article] (R)-[11C]Emopamil as a novel tracer for imaging enhanced P-glycoprotein function. (R)-[11C]Emopamil as a novel tracer for imaging enhanced P-glycoprotein function.2016

    • Author(s)
      Jun Toyohara, Mayumi Okamoto, Hiroki Aramaki, Yuto Zaitsu, Isao Shimizu, Kiichi Ishiwata.
    • Journal Title

      Nuclear Medicine and Biology

      Volume: 43 Issue: 1 Pages: 52-63

    • DOI

      10.1016/j.nucmedbio.2015.09.001

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26870647, KAKENHI-PROJECT-25293271
  • [Journal Article] Importance of P-gp PET imaging in pharmacology.2016

    • Author(s)
      Toyohara J.
    • Journal Title

      Curr. Pharm. Des.

      Volume: 22 Issue: 38 Pages: 5830-5863

    • DOI

      10.2174/1381612822666160804092258

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Journal Article] Comparison of 4DST and FDG PET/CT imaging for advanced renal cell carcinoma: preliminary study.2016

    • Author(s)
      Minamimoto R, Nakaigawa R, Nagashima Y, Toyohara J, Ueno D, Namura K, Nakajima K, Yao M, and Kubota K,
    • Journal Title

      Abode Radiol

      Volume: 41 Issue: 3 Pages: 521-530

    • DOI

      10.1007/s00261-015-0601-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293271, KAKENHI-PROJECT-26461874
  • [Journal Article] Evaluation of DNA synthesis with carbon-11-labeled 4-thiothymidine.2016

    • Author(s)
      Toyohara J.
    • Journal Title

      World J. Radiol.

      Volume: 8 Issue: 9 Pages: 799-808

    • DOI

      10.4329/wjr.v8.i9.799

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Journal Article] Volumetric comparison 4'-[methyl-11C]-thiothymidine with 18F-FDG PET/CT in patients with advanced head and neck squamous cell carcinoma2015

    • Author(s)
      Ito K, Yokoyama J, Miyata Y, Toyohara J, Okasaki M, Minamimoto R, Morooka M, Ishiwata K, Kubota K
    • Journal Title

      Nucl Med Commun

      Volume: 36 Pages: 219-225

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Journal Article] In vitro analysis of transport and metabolism of 4'-thiothymidine in human tumor cells.2015

    • Author(s)
      Plotnik DA, Wu S, Linn GR, Yip FCT, Comandante NL, Kroc KA, Toyohara J, and Schwartz JL.
    • Journal Title

      Nucl Med Biol

      Volume: 42 Issue: 5 Pages: 470-474

    • DOI

      10.1016/j.nucmedbio.2014.12.005

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Journal Article] Comparison of 4'-[methyl-(11)C]thiothymidine ((11)C-4DST) and 3'-deoxy-3'-[(18)F]fluorothymidine ((18)F-FLT) PET/CT in human brain glioma imaging2015

    • Author(s)
      Toyota, Y. Miyake, K. Kawai, N. Hatakeyama, T. Yamamoto, Y. Toyohara, J. Nishiyama, Y. Tamiya, T.
    • Journal Title

      EJNMMI Res

      Volume: 5 Issue: 1 Pages: 7-7

    • DOI

      10.1186/s13550-015-0085-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23390344, KAKENHI-PROJECT-26293324, KAKENHI-PROJECT-25461828
  • [Journal Article] Comparison of dosimetry between PET/CT and PET alone using 11C-ITMM.2015

    • Author(s)
      Ito K, Sakata M, Oda K, Wagatsuma K, Toyohara J, Ishibashi K, Ishii K, Ishiwata K.
    • Journal Title

      Australas Phys. Eng. Sci. Med.

      Volume: 39 Issue: 1 Pages: 177-186

    • DOI

      10.1007/s13246-015-0419-5

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390298, KAKENHI-PROJECT-25293271
  • [Journal Article] Comparison of (11)C-4'-thiothymidine, (11)C-methionine, and (18)F-FDG PET/CT for the detection of active lesions of multiple myeloma2015

    • Author(s)
      Okasaki, M. Kubota, K. Minamimoto, R. Miyata, Y. Morooka, M. Ito, K. Ishiwata, K. Toyohara, J. Inoue, T. Hirai, R. Hagiwara, S. Miwa, A.
    • Journal Title

      Ann Nucl Med

      Volume: 29 Pages: 224-232

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390344
  • [Journal Article] Synthesis and evaluation of 7α-(3-[18F]fluoropropyl) estradiol.2015

    • Author(s)
      2.Mayumi Okamoto, Kyosuke Naka, Yuya Kitagawa, Kiichi Ishiwata, Mitsuyoshi Yoshimoto, Isao Shimizu, Jun Toyohara.
    • Journal Title

      Nuclear Medicine and Biology

      Volume: 42 Issue: 7 Pages: 590-597

    • DOI

      10.1016/j.nucmedbio.2015.03.005

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26870647, KAKENHI-PROJECT-25293271
  • [Journal Article] Comparison of (11)C-4'-thiothymidine, (11)C-methionine, and (18)F-FDG PET/CT for the detection of active lesions of multiple myeloma.2015

    • Author(s)
      Okasaki M, Kubota K, Minamimoto R, Miyata Y, Morooka M, Ito K, Ishiwata K, Toyohara J, Inoue T, Hirai R, Hagiwara S, Miwa A.
    • Journal Title

      Ann Nucl Med

      Volume: 29 Issue: 3 Pages: 224-232

    • DOI

      10.1007/s12149-014-0931-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24591807, KAKENHI-PROJECT-25293271, KAKENHI-PROJECT-26461874
  • [Journal Article] Comparison of 4'-[methyl-11C]thiothymidine (11C-4DST) and 3'-deoxy-3'-[18F]fluorothymiein (18F-FLT) PET/CT in human brain glioma imaging2015

    • Author(s)
      Toyota Y, Miyake K, Kawai N, Hatakeyama, T, Yamamoto Y, Toyohara J, NIshiyama Y, Tamiya T
    • Journal Title

      EJNMMI Research

      Volume: 5 Pages: 7-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Journal Article] A pilot study of 4'-[methyl-11C]-thothymidine PET/CT for detection of regional lymph node metastasis in non-small cell lung cancer.2014

    • Author(s)
      Minamimoto R, Toyohara J, Ito H, Seike A, Miyata Y, Morooka M, Okasaki M, Nakajima K, Ito K, Ishiwata K and Kubota K
    • Journal Title

      European Journal of Nuclear Medicine and Molecular Imaging Research

      Volume: 4 Issue: 1 Pages: 10-10

    • DOI

      10.1186/2191-219x-4-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Journal Article] Changes in cerebral blood flow during steady-state cycling exercise: a study using oxygen-15-labeled water with PET2014

    • Author(s)
      Hiura, M. Nariai, T. Ishii, K. Sakata, M. Oda, K. Toyohara, J. Ishiwata, K.
    • Journal Title

      J Cereb Blood Flow Metab

      Volume: 34 Issue: 3 Pages: 389-396

    • DOI

      10.1038/jcbfm.2013.220

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390344, KAKENHI-PROJECT-24500478, KAKENHI-PROJECT-26670637
  • [Journal Article] Longitudinal observation of ^<11>C-4DST uptake in turpentine-induced inflammatory tissue.2013

    • Author(s)
      Toyohara, J., Sakata, M., Oda, K., Ishii, K. and Ishiwata, K.
    • Journal Title

      Nucl. Med. Biol.

      Volume: 40 Issue: 2 Pages: 240-244

    • DOI

      10.1016/j.nucmedbio.2012.10.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390241, KAKENHI-PROJECT-23390344
  • [Journal Article] Initial human PET studies of metabotropic glutamate receptor type 1 ligand ^<11>C-ITMM2013

    • Author(s)
      Toyohara J., Sakata M., Oda K., Ishii K, Ito K., Hiura M., Fujinaga M., Yamasaki T., Zhang M.R., and Ishiwata K.
    • Journal Title

      J. Nucl. Med.

      Volume: 54(8)(in press) Issue: 8 Pages: 1302-1307

    • DOI

      10.2967/jnumed.113.119891

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390298
  • [Journal Article] Preclinical and the first clinical studies on [11C]ITMM for mapping metabotropic glutamate receptor type 1 by positron emission tomography2013

    • Author(s)
      Toyohara J.,Zhang M.-R.
    • Journal Title

      Nuclear Medicine and Biology

      Volume: 40 Issue: 2 Pages: 214-220

    • DOI

      10.1016/j.nucmedbio.2012.11.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591379, KAKENHI-PROJECT-24390298
  • [Journal Article] Roles of sigmal receptors in the mechanisms of action of CNS drugs.2012

    • Author(s)
      Toyohara, J., Sakata, M. and Ishiwata, K.
    • Journal Title

      Trans. Neurosci.

      Volume: 3 Issue: 3 Pages: 294-299

    • DOI

      10.2478/s13380-012-0030-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390241, KAKENHI-PROJECT-23659605
  • [Journal Article] 腫瘍イメージング剤 DNA合成イメージング剤 4DST. 特集 PET 薬剤と合成装置の進歩2012

    • Author(s)
      豊原潤
    • Journal Title

      PETジャーナル

      Volume: 20 Pages: 39-41

    • Data Source
      KAKENHI-PROJECT-22390241
  • [Journal Article] Application of[^<11>C]SA4503 to selection of novel sigmal selective agonists.2012

    • Author(s)
      Toyohara, J., Kobayashi, T., Mita, S. and Ishiwata, K.
    • Journal Title

      Nucl. Med. Biol.

      Volume: 39 Issue: 8 Pages: 1117-1121

    • DOI

      10.1016/j.nucmedbio.2012.06.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390241, KAKENHI-PROJECT-23659605
  • [Journal Article] Re-evaluation of in vivo selectivity of [^<11>C]SA4503 to sigmal receptors in the brain : contributions of emopamil binding protein.2012

    • Author(s)
      Toyohara, J., Sakata, M. and Ishiwata, K
    • Journal Title

      Nucl. Med. Biol.

      Volume: 39 Issue: 7 Pages: 1049-1052

    • DOI

      10.1016/j.nucmedbio.2012.03.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390241, KAKENHI-PROJECT-23659605
  • [Journal Article] ^<11>C-4DST PET/CT for proliferation imaging in non-small-cell-lung cancer.2012

    • Author(s)
      Minamimoto, R., Toyohara, J., Seike, A., Ito, H., Endo, H., Mooorka, M., Nakajima, K., Mitsumoto, T., Ito, K., Okasaki, M., Ishiwata, K. and Kubota K.
    • Journal Title

      J. Nucl. Med.

      Volume: 53 Issue: 2 Pages: 199-206

    • DOI

      10.2967/jnumed.111.095539

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Journal Article] Evaluation of 4'-[methyl-^<11>C]thiothymidine (^<11>C-4DST) in a rodent tumor and inflammation model.2012

    • Author(s)
      Toyohara, J., Elsinga, P. H., Ishiwata, K., Sijbesma, J. W. A. Dierckx, R. A. J. 0. and van Waarde, A.
    • Journal Title

      J. Nucl. Med.

      Volume: 53 Issue: 3 Pages: 488-494

    • DOI

      10.2967/jnumed.111.098426

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390241, KAKENHI-PROJECT-23390344
  • [Journal Article] Animal tumor models for PET in drug development2011

    • Author(s)
      Toyohara J, et al
    • Journal Title

      Annals of Nuclear Medicine

      Volume: 25 Issue: 10 Pages: 717-731

    • DOI

      10.1007/s12149-011-0531-x

    • NAID

      10030233402

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Journal Article] Whole-body distribution and brain tumor imaging with ^<11>C-4DST : a pilot study2011

    • Author(s)
      Toyohara J, et al
    • Journal Title

      The Journal of Nuclear Medicine

      Volume: 52 Issue: 8 Pages: 1322-1325

    • DOI

      10.2967/jnumed.111.088435

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390241, KAKENHI-PROJECT-23390344
  • [Journal Article] Biodistribution and radiation dosimetry of the α-7 nicotinic acetylcholine receptor ligand [^<11>C]CHIBA-1001 in humans.2011

    • Author(s)
      Sakata M, Wu J, Toyohara J, Oda K, Ishikawa M, Ishii K, Hashimoto K, Ishiwata K.
    • Journal Title

      Nucl.Med.Biol.

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390334
  • [Journal Article] Whole-body distribution and brain tumor imaging with ^<11>C-4DST : a pilot study.2011

    • Author(s)
      Toyohara J, Nariai T, Sakata M, Oda K, Ishii K, Kawabe T, Iris T, Saga T, Kubota K, Ishiwata K.
    • Journal Title

      J. Nucl. Med.

      Volume: In press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390334
  • [Journal Article] Whole-body distributiona dn brain tumor imaging with ^<11>C-4DST : a pilot study.2011

    • Author(s)
      Toyohara J, Nariai T, Sakata M, Oda K, Ishii K, Kawabe T, Irie T, Saga T, Kubota K, Ishiwata K.
    • Journal Title

      The Journal of Nuclear Medicine

      Volume: in press Pages: 52-52

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Journal Article] Whole-body distribution and brain tumor imaging with ^<11>C-4DST : a pilot study.2011

    • Author(s)
      Toyohara, J., Nariai, T., Sakata, M., Oda, K., Ishii, K., Kawabe, T., Irie, T., Saga, T., Kubota, K. and Ishiwata, K.
    • Journal Title

      J. Nucl. Med.

      Volume: 52 Pages: 1322-1328

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Journal Article] Animal tumor models for PET in drug development.2011

    • Author(s)
      Toyohara, J. and Ishiwata, K.
    • Journal Title

      Ann. Nucl. Med.

      Volume: 25 Pages: 717-731

    • NAID

      10030233402

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Journal Article] ヌクレオシド誘導体プローブとそれによる腫瘍イメージング 特集1腫瘍のイメージング2011

    • Author(s)
      豊原潤
    • Journal Title

      PETジャーナル

      Volume: 13 Pages: 15-16

    • Data Source
      KAKENHI-PROJECT-22390241
  • [Journal Article] FDG以外のPET製剤2010

    • Author(s)
      豊原潤
    • Journal Title

      臨床泌尿器科

      Volume: 64 Pages: 751-756

    • Data Source
      KAKENHI-PROJECT-22390241
  • [Journal Article] Imaging of sigmai receptors in the human brain using PET and [^<11>C]SA45032009

    • Author(s)
      Toyohara J, Sakata M, Ishiwata K.
    • Journal Title

      CNS Agents Med.Chem. 9

      Pages: 190-196

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390334
  • [Journal Article] Imaging of sigma_1 receptors in the human brain using PET and [11C]SA4503.2009

    • Author(s)
      Toyohara J, Sakata M, Ishiwata K.
    • Journal Title

      CNS Agents Med Chem 9

      Pages: 190-196

    • Data Source
      KAKENHI-PROJECT-20390334
  • [Journal Article] Imaging of sigmai receptors in the human brain using PET and [^<11>C]SA4503

    • Author(s)
      Toyohara J
    • Journal Title

      CNS Agents Med Chem (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390334
  • [Presentation] [18F]MK6240.PET化学 てびき第6版 その3(神経病理)2024

    • Author(s)
      豊原潤
    • Organizer
      PET化学ワークショップ2024
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] [18F]MC225.PET化学 てびき第6版 その2(神経機能)2024

    • Author(s)
      豊原潤
    • Organizer
      PET化学ワークショップ2024
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] [18F]NAV4694.PET化学 てびき第6版 その3(神経病理)2024

    • Author(s)
      豊原潤
    • Organizer
      PET化学ワークショップ2024
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] てびき第6版の概要.PET化学 てびき第6版 その1(基礎技術)2024

    • Author(s)
      豊原潤
    • Organizer
      PET化学ワークショップ2024
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] [11C]Preladenant.PET化学 てびき第6版 その2(神経機能)2024

    • Author(s)
      豊原潤
    • Organizer
      PET化学ワークショップ2024
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] パーキンソン病患者におけるコーヒー摂取後のアデノシンA2A受容体占拠率2023

    • Author(s)
      石橋賢士、三浦義治、上高祐人、多胡哲朗、坂田宗之、豊原潤、石井賢二
    • Organizer
      第64回日本神経学会大会
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] Optimization of the automated radiosynthesis of an 18F-labeled tetrahydroquinoline derivative for brain HDAC6 imaging.2023

    • Author(s)
      Tago T, Toyohara J, Ishii K.
    • Organizer
      The 25th International Symposium on Radiopharmaceutical Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] 選択的モノアミンオキシゲナーゼB結合リガンド[18F]SMBT-1の臨床使用に向けた多目的合成装置による製造法の検討2023

    • Author(s)
      豊原潤、多胡哲郎、西野浩輔、酒井昌成、石井賢二
    • Organizer
      日本薬学会第143年会
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] Texture indices extrcted from FLT and 4'-[methyl-11C]thiothymidine (4DST) PET/CT to distinguish tumor grade in newly diagnosed high-grade glioma.2023

    • Author(s)
      Yamamoto Y, Mitamura K, Norikane T, Toyohara J, Nishiyama Y.
    • Organizer
      SNMMI 2023 Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] Age-dependent decline of the P-glycoprotein function at the blood-brain barrier: preliminary observation with newly developed PET tracer fluorine-18 labelled MC225.2023

    • Author(s)
      Toyohara J, Sakata M, Ishibashi K, Wagatsuma K, Tago T, Imabayashi E, Ishii K.
    • Organizer
      IAGG Asia/Oceania Regional Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] Fully automated radiosynthesis of [18F]SMBT-1 for clinical use2023

    • Author(s)
      Toyohara J, Tago T, Ishii K.
    • Organizer
      The 25th International Symposium on Rediopharmaceutical Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] 電子求引性置換基を有するベンゼンスルホン酸エステルを前駆体として用いるネオペンチル18F標識化の検討2023

    • Author(s)
      田中浩士、飯田翔悟、多胡哲郎、多田匡利、河原琉晟、豊原潤
    • Organizer
      第63回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] 脳FDG画像の新旧機種間差補正における機械学習の利用2023

    • Author(s)
      坂田宗之、上高祐人、我妻慧、石橋賢士、多胡哲朗、豊原潤、石井賢二
    • Organizer
      第63回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] PET用脳内ヒストンデアセチラーゼ6イメージングプローブの開発2023

    • Author(s)
      多胡哲朗、豊原潤、石井賢二
    • Organizer
      第11回TOBIRA研究交流フォーラム
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] Implementation of amyloid PET in a memory clinic of geriatric hospital revealed characteristics of causative diseases by age.2023

    • Author(s)
      Ishii K, Ishibashi K, Sakata M, Kamitaka Y, Tago T, Kameyama M, Kanemaru K, Murayama S, Iwata A, Toyohara J.
    • Organizer
      Alzheimer's Association International Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] 脳PET臨床計測におけるデータ駆動短時間フレーム体動補正法の利用2023

    • Author(s)
      坂田宗之、上高祐人、甲木晶枝、川上泰史、我妻慧、織田圭一、石橋賢士、多胡哲郎、豊原潤、石井賢二
    • Organizer
      第63回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] PET用HDAC6プローブ[18F]FSW-100の被ばく線量推定と毒性試験2023

    • Author(s)
      多胡哲朗、坂田宗之、豊原潤
    • Organizer
      第63回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] PET用HDAC6イメージングプローブ[18F]FSW-100の自動合成最適化2023

    • Author(s)
      多胡哲郎、豊原潤、石井賢二
    • Organizer
      日本薬学会第143年会
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] プレクリニカル期アルツハイマー病のアミロイド蓄積に相関する大脳皮質の萎縮について2022

    • Author(s)
      今林悦子、豊原潤、多胡哲郎、坂田宗之、我妻慧、石橋賢士、石井賢二
    • Organizer
      第62回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] Occupancy of adenosine A2A receptors after coffee intake in patients with Parkinson’s disease2022

    • Author(s)
      Ishibash, K, Miura Y, Kamitaka Y, Tago T, Sakata M, Toyohara J, Ishii K
    • Organizer
      The 13th congress of the world federation of nuclear medicine and biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] PET imaging of neuroinflammation2022

    • Author(s)
      Toyohara J
    • Organizer
      Japan-Korea joint symposium in the 45th annual meeting of the japan society for biomedical gerontology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] Regional cerebral atrophy correlate with amyloid accumulation in preclinical Alzheimer’s disease2022

    • Author(s)
      Imabayashi E, Ishii K, Toyohara J, Kojima N, Tago T, Sakata M, Wagatsuma K, Ishibashi K, Tokumaru AM, Kim H
    • Organizer
      Alzheimer’s association international conference 2022
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] [18F]flutemetamolの軽度認知障害期における側頭葉内側部集積について2022

    • Author(s)
      今林悦子、豊原潤、多胡哲郎、坂田宗之、石橋賢士、石井賢二
    • Organizer
      第41回日本認知症学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] Longitudinal changes in 18F-FDG uptake in two elderly patients with Alzheimer’s disease2022

    • Author(s)
      Ishibashi K, Onishi A, Kamitaka Y, Tago T, Sakata M, Toyohara J, Ishii K
    • Organizer
      第63回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] Comparative pathological study of carbon-11 labeled pittsburgh compound-B PET centiloid scale and amyloid beta deposition in postmortem brains2022

    • Author(s)
      Matsubara T, Murayama S, Ihara R, Higashihara M, Nishina Y, Kanemaru K, Iwata A, Arai T, Kameyama M, Tokumaru AM, Imabayashi E, Ishibashi K, Toyohara J, Saito Y, Ishii K
    • Organizer
      Alzheimer’s association international conference 2022
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] 放射性薬剤の製造と品質管理2022

    • Author(s)
      豊原潤
    • Organizer
      第21回日本核医学会春季大会放射性医薬品エキスパートセミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] 新規脳内HDAC6 PETイメージングプローブの開発2022

    • Author(s)
      多胡哲郎、豊原潤、石井賢二
    • Organizer
      第62回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] [18F] Flutemetamol によるアミロイドPET定量化のためのアルゴリズム開発について2022

    • Author(s)
      今林悦子、豊原潤、坂田宗之、石橋賢士、上髙祐人、石井賢二
    • Organizer
      第62回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] アミロイドPETにおけるデータ駆動短時間フレーム体動補正法の検討2022

    • Author(s)
      坂田宗之、上髙祐人、甲木章枝、川上弘文、我妻慧、織田圭一、石橋賢士、多胡哲郎、豊原潤、石井賢二
    • Organizer
      第62回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] [18F] Flutemetamol によるアミロイドPETの軽度認知障害期における側頭葉内側部の集積について2022

    • Author(s)
      今林悦子、豊原潤、多胡哲郎、坂田宗之、我妻慧、石橋賢士、石井賢二
    • Organizer
      第62回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] プレクリニカル期およびMCI期におけるアミロイド蓄積に相関する大脳皮質の萎縮について2022

    • Author(s)
      今林悦子、豊原潤、多胡哲郎、坂田宗之、石橋賢士、石井賢二
    • Organizer
      第41回日本認知症学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] Amyloid accumulation in medial temporal area starts in MCI stage in [18F]flutemetamol PET2022

    • Author(s)
      Imabayashi E, Ishii K, Toyohara J, Kojima N, Tago T, Sakata M, Wagatsuma K, Ishibashi K, Tokumaru AM, Kim H
    • Organizer
      Alzheimer’s association international conference 2022
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] Experience of GMP for investigational products in academic research institute.2022

    • Author(s)
      Toyohara J
    • Organizer
      IAEA regional training course on good manufacturing practice (GMP) and radiation safety aspects of radiopharmaceutical production using medical cyclotron (IAEA/RCA RAS6097)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] 有酸素運動の強度変化に伴う前頭葉皮質における脳血流酸素代謝カップリングの考察2022

    • Author(s)
      日浦幹夫、坂田宗之、成相直、石橋賢士、我妻慧、多胡哲郎。豊原潤、石井賢二、片山容一
    • Organizer
      第65回日本脳循環代謝学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] Radiosynthesis and biological evaluation of a nicotinic acid hydroxamate derivative as a radioligand for HDAC6 PET imaging.2022

    • Author(s)
      Tago T, Toyohara J, Ishii K
    • Organizer
      International symposium on radiopharmaceutical sciences.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] ネオペンチル標識基を利用するラジオセラノスティクス薬剤の合成研究2021

    • Author(s)
      劉紫昀、ソウエイソウ、多胡哲郎、西岡成汰、熊添基文、岩井久美子、平野圭市、立花宏文、豊原潤、田中浩士
    • Organizer
      日本ケミカルバイオロジー学会第15回年会
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] 11C-PiB PETを実施した22剖検例におけるCentiloidと病理診断との対比2021

    • Author(s)
      松原知康、齊藤祐子、村山繁雄、新井冨生、井原涼子、東原真奈、仁科裕史、金丸和富、岩田淳、亀山征史、今林悦子、德丸阿耶、石橋賢士、豊原潤、石井賢二
    • Organizer
      第40回日本認知症学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] プレクリニカル期アルツハイマー病における側頭葉内側部の容積について2021

    • Author(s)
      今林悦子、石井賢二、豊原潤、坂田宗之、我妻慧、石橋賢士、多胡哲郎、德丸阿弥、小島成美、金憲経
    • Organizer
      第61回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] Occupancy of adenosine A2A receptors after long term use of istradefylline in Parkinson's disease2021

    • Author(s)
      Ishibashi K, Miura Y, Tago T, Wagatsuma K, Sakata M, Toyohara J, Ishii K
    • Organizer
      第62回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] 18F-標識ネオペンチル側鎖を有する化合物の固相抽出精製法による標識合成2021

    • Author(s)
      多胡哲郎、豊原潤、ソウエイソウ、田中浩士
    • Organizer
      第4回日本核医学会分科会放射性薬品科学研究会
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] 新規P-糖タンパク質イメージング剤[18F]MC225の初期臨床評価2021

    • Author(s)
      豊原潤、坂田宗之、石橋賢士、我妻慧、多胡哲郎、今林悦子、Nicola Colabufo、Gert Luurtsema、石井賢二
    • Organizer
      第61回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] 放射性薬剤の製造と品質管理2021

    • Author(s)
      豊原潤
    • Organizer
      第21回日本核医学会春季大会放射性医薬品エキスパートセミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] Development of a PET probe for histone deacetylase 6 in the brain2021

    • Author(s)
      Tago T, Toyohara J, Ishii K
    • Organizer
      第61回日本核医学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] 新規P-糖タンパク質イメージング剤[18F]MC225の全身PET計測による被ばく線量評価2021

    • Author(s)
      豊原潤、坂田宗之、石橋賢士、我妻慧、多胡哲郎、今井昌康、Nicola Colabufo、Gert Luurtsema、石井賢二
    • Organizer
      第61回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] 高齢者地域コホートにおける脳内アミロイド蓄積と局所脳容積について2021

    • Author(s)
      今林悦子、石井賢二、豊原潤、坂田宗之、我妻慧、石橋賢士、多胡哲郎、德丸阿耶、小島成実、小林洋大、甲田哲之、金憲経
    • Organizer
      第40回日本認知症学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] Istradefylline長期内服によるアデノシンA2A受容体占拠率2021

    • Author(s)
      石橋賢士、我妻慧、多胡哲郎、坂田宗之、豊原潤、石井賢二
    • Organizer
      第61回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] SPMを用いた脳FDG画像の統計比較における新旧機種の機種間差補正の検討2021

    • Author(s)
      坂田宗之、我妻慧、織田圭一、今林悦子、上髙祐人、石橋賢士、多胡哲郎、豊原潤、石井賢二
    • Organizer
      第61回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] Characteristics of cerebral blood flow elicited by exercise intervention for patients with hypertension and uschemic cerebrovascular disease2021

    • Author(s)
      Hiura M, Nariai T, Sakata M, Toyohara J, Ishibashi K, Wagatsuma K, Ishii K, Katayama Y
    • Organizer
      Sporst, Medicine and Health Summit
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] Radiosynthesis and preliminary evaluation of a novel 18F-labeled probe for PET imaging of HDAC6 in the brain2021

    • Author(s)
      Tago T, Toyohara J, Ishii K
    • Organizer
      The 11th China-Japan-Korea Symposium on Radiopharmaceutical Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07663
  • [Presentation] Head to head comparison of [15O]H2O and [11C]MMP in non-human primates; tracers for measuring regional cerebral blood flow.2020

    • Author(s)
      Toyohara, J., Kakiuchi, T., Ohba, H., Kanazawa, M., Tago, T., Sakata, M., Harada, N.
    • Organizer
      EANM'20 Virtual Event
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] 虚血性脳血管障害における運動中の脳血流量の特徴:PET研究2020

    • Author(s)
      日浦幹夫、成相直、坂田宗之、石橋賢士、我妻慧、多胡哲郎、豊原潤、石井賢二、片山容一
    • Organizer
      第60回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] 施設認証の必須項目の詳細(1)PET薬剤の製造および試験検査の基礎2020

    • Author(s)
      豊原潤
    • Organizer
      第20回日本核医学会春季大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] Efficacy of 4DST-PET/CT for predicting the prognosis in patients with esophageal cancer: a comparison study with FDG-PET/CT.2020

    • Author(s)
      Hotta, M., Minamimoto, R., Yamada, K., Toyohara, J.
    • Organizer
      SNMMI 2020 Annual Meeting Virtual Events
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] ネオペンチル側鎖を利用した18F-標識合成における副生成物の評価2020

    • Author(s)
      多胡哲郎、豊原潤、ソウエイソウ、龍田真帆、平野圭市、岩井久美子、田中浩士
    • Organizer
      第60回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] COX-2イメージング剤を目的とした二メスリド[11C]Me/[18F]OFEt誘導体の開発2020

    • Author(s)
      山本由美、多胡哲郎、豊原潤、斎藤陽平、山本文彦
    • Organizer
      第60回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] Potential use of 18F-THK5351 PET to identify astrogliosis in neurological disease.2020

    • Author(s)
      Ishibashi, K., Tago, T., Wagatsuma, K., Sakata, M., Toyohara, J., Ishii, K.
    • Organizer
      American Society of Neurology Annual Meeting 2000 Virtual Event
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] 新規脳血流PETイメージング剤[11C]MMP:覚醒サルにおける[15O]H2Oとの直接比較2020

    • Author(s)
      豊原潤、垣内岳春、大庭弘行、金澤将勝、多胡哲郎、坂田宗之、原田典弘
    • Organizer
      第60回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] 18F-標識ネオペンチルスチリルピリジンアミロイド-β PETプローブの生物学的評価2020

    • Author(s)
      多胡哲郎、豊原潤、ソウエイソウ、龍田真帆、新崎智子、柳井修一、遠藤昌吾、斉藤貴志、西道隆臣、田中浩士
    • Organizer
      第60回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] Occupancy of adenosine A2A receptors after ustradefylline administration2020

    • Author(s)
      石橋賢士、多胡哲郎、我妻慧、坂田宗之、豊原潤、石井賢二
    • Organizer
      第60回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] フッ化物イオンの求核置換反応を用いる18F-標識化において生じる副生成物に関する研究2020

    • Author(s)
      ソウエイソウ、多胡哲郎、豊原潤、田中浩士
    • Organizer
      日本化学会第100春季大会(web開催)
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] [18F]MC225特定臨床研究への道2020

    • Author(s)
      豊原潤
    • Organizer
      PET化学ワークショップ2020
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] FDG画像の機械学習を用いた認知症鑑別診断支援における特徴量増加による精度向上の検討2020

    • Author(s)
      坂田宗之、我妻慧、多胡哲郎、石橋賢士、豊原潤、石井賢二
    • Organizer
      第60回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] 18F-標識ネオペンチルスチルベンアミロイドPETプローブの固相抽出精製による合成2020

    • Author(s)
      多胡哲郎、豊原潤、龍田真帆、ソウエイソウ、平野圭一、岩井久美子、石橋賢士、田中浩士
    • Organizer
      日本薬学会第140年会(web開催)
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] 脳内HDAC6 PETイメージングのための18F-標識テトラヒドロキノリン誘導体の開発2020

    • Author(s)
      多胡哲郎、豊原潤、石井賢二
    • Organizer
      第60回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] Adenosine A2A receptor occupancy by istradefylline in Parkinson's disease, using 11C-preladenant PET.2020

    • Author(s)
      石橋賢士、三浦義治、多胡哲郎、我妻慧、坂田宗之、豊原潤、石井賢二
    • Organizer
      第61回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] PET薬剤の製造および試験検査の基礎2019

    • Author(s)
      豊原潤
    • Organizer
      第18回日本核医学会春季大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] 18F-THK5351 PET Imaging of Wallerian Degeneration of the Pyramidal Tract in a Post-Stroke Patient: A Longitudinal Case Study2019

    • Author(s)
      Ishibashi, K., Tago, T., Toyohara, J., Ishii, K.
    • Organizer
      American Heart/Stroke Association International Stroke Conference 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] HDAC6イメージングを目的とした18F-標識ツバスタチンA類縁体の標識合成と生物学的評価2019

    • Author(s)
      多胡哲郎、豊原潤、石井賢二
    • Organizer
      第14回日本分子イメージング学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] アミロイド陽電子断層撮像(PET)の臨床使用へ向けた撮像条件の検討2019

    • Author(s)
      我妻慧、石橋賢士、坂田宗之、多胡哲郎、豊原潤、石井賢二
    • Organizer
      首都大学バイオコンファレンス2019
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] Fully automated radiosynthesis of [18F]MK-6240 for clinical use.2019

    • Author(s)
      Toyohara J, Tago T, Nishino K, Sakai M, Ishii K.
    • Organizer
      EANM'19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] 放射性フッ素-18標識希少糖の生物学的評価2019

    • Author(s)
      豊原潤、山本浩之、多胡哲郎、茨木正信、木下俊文
    • Organizer
      第14回日本分子イメージング学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] 11C-Preladenantを用いたアデノシンA2A受容体定量測定の再現性検討2019

    • Author(s)
      坂田宗之、我妻慧、多胡哲郎、石橋賢士、石井賢二、石渡喜一、豊原潤
    • Organizer
      第59回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] Test-retest reliability of adenosine A2A binding in the human brain with 11C-preladenent PET.2019

    • Author(s)
      Sakata M, Wagatsuma K, Tago T, Ishibashi K, Ishii K, Ishiwata K, Toyohara J.
    • Organizer
      EANM'19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] Off-target bindingを有するアミロイド・タウPETトレーサーのための特異的集積量推定法2019

    • Author(s)
      徳田明日香、田中美香、多胡哲郎、石橋賢士、我妻慧、坂田宗之、井上一雄、福士政広、豊原潤、石井賢二
    • Organizer
      第59回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] [18F]Florbetapir PETにおける白質参照領域の優位性の源泉2019

    • Author(s)
      亀山征史、石橋賢士、豊原潤、石井賢二
    • Organizer
      第59回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] ネオペンチル標識基を用いるスチリルピリジン型AβPETトレーサーの合成研究2019

    • Author(s)
      ソウエイソウ、多胡哲郎、藤牧諒、龍田真帆、岩井久美子、平野圭一、石橋賢士、豊原潤、田中浩士
    • Organizer
      第9回CSJ化学フェスタ2019
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] 高悪性度神経膠腫再発における4DSTの取り込み:治療誘発性壊死との比較2019

    • Author(s)
      安賀文俊、山本由佳、三田村克哉、豊原潤、西山佳宏
    • Organizer
      第59回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] Biological evaluations of fluorine-18 labeled D-allose.2019

    • Author(s)
      Toyohara J, Yamamoto H, Tago T, Ibaraki M, Kinoshita T, Ishii K.
    • Organizer
      World Molecular Imaging Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] ネオペンチル標識基を用いるスチリルピリジン型AβPETトレーサーの合成研究2019

    • Author(s)
      ソウエイソウ、多胡哲郎、藤牧諒、龍田真帆、豊原潤、平野圭一、岩井久美子、田中浩士
    • Organizer
      第77回有機合成化学協会関東支部シンポジウム
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] ネオペンチル標識基を有するスチリルピリジン型Aβ[18F]PETトレーサーの合成研究2019

    • Author(s)
      Song Ruichong、多胡哲郎、藤牧諒、龍田真帆、豊原潤、平野圭市、岩井久美子、石橋賢士、田中浩士
    • Organizer
      日本化学会第99春季年会
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] 臨床使用を目的とした[18F]MK-6240の自動合成とバリデーション2019

    • Author(s)
      豊原潤、多胡哲郎、西野浩輔、酒井昌成、石井賢二
    • Organizer
      第59回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] 18F-標識PETプローブ合成のための簡便な固相抽出精製法の開発2019

    • Author(s)
      多胡哲郎、豊原潤、藤牧諒、平野圭一、岩井久美子、田中浩士
    • Organizer
      TOBIRA第8回研究フォーラム
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] Alterations in cerebral blood flow evoked by dynamic exercise in post-stroke patients implies a mechanism for cerebral autoregulation: a PET study.2019

    • Author(s)
      Hiura M, Nariai T, Sakata M, Muta A, Ishibashi K, Wagatsuma K, Tago T, Toyohara J, Ishii K, Katayama Y.
    • Organizer
      Brain & Brain PET 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] Pharmacokinetics modeling of P-glycoprotein function at the blood-brain brrier with [18F]MC225 in non-human primates.2019

    • Author(s)
      Garcia Varle L, Arif WM, Gardia Vallez D, Kakiuchi T, Ohba H, NIshiyama S, Tago T, Elsinga PH, Tsukada H, Colabufo NA, Dierckx RAJO, van Waarde A, Toyohara J, Boellaard R, Luurtsema G.
    • Organizer
      EANM'19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] 18F-THK5351 PET can identify Wallerian degeneration of the pyramidal tract in a post-stroke patient2019

    • Author(s)
      石橋賢士、三浦義治、亀山征史、多胡哲郎、豊原潤、石井賢二
    • Organizer
      第60回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] 早期アルツハイマー病における代謝型グルタミン酸受容体1型2019

    • Author(s)
      石橋賢士、多胡哲郎、我妻慧、坂田宗之、豊原潤、石井賢二
    • Organizer
      第59回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] Dosimetry and toxicology of [18F]MC225 for measuring P-glycoprotein function at the blood-brain barrier in humans.2019

    • Author(s)
      Toyohara J, Sakata M, Tago T, Colabufo N, Luurtsema G.
    • Organizer
      The 23rd I nternational Symposium on Radiopharmaceutical Sciences 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] Cerebral type 1 metabotropic glutamate receptor availability in early Alzheimer's disease.2019

    • Author(s)
      Ishibashi K, Tago T, Wagatsuma K, Sakata M, Toyohara J, Ishii K.
    • Organizer
      Neuroscience 2019. Society for Neuroscience.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] Relationship between symptoms and regional density of metabotropic glutamate receptor subtype 1 measured with 11C-ITMM PET in de novo Parkinson's disease.2019

    • Author(s)
      Mishina M, Suzuki M, Ishii K, Sakata M, Wagastuma K, Ishibashi K, Toyohara J, Zhang MR, Kimura K, Ishiwata K.
    • Organizer
      The MDS International Congress of Parkinson's Disease and Movement Disorders 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] A simple SPE purification method for 18F-radiolabeling: Proof-of-concept study in stilbene amyloid-β ligands with a noepentyl labeling group.2019

    • Author(s)
      Tago T, Toyohara J, Fujimaki R, Hirano K, Iwai K, Ishibashi K, Tanaka H.
    • Organizer
      The 23rd International Symposium on Radiopharmaceutical Sciences 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] Edge artifacts attributable to point spread function correction included in reconstruction for brain PET imaging.2019

    • Author(s)
      Sakata M, Wagatsuma K, Hirayama A, Kawakami H, Toyohara J, Ishii K.
    • Organizer
      Brain & Brain PET 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] 医学・医療研究を支えるPET薬剤の開発2019

    • Author(s)
      豊原潤
    • Organizer
      TOBIRA第8回研究交流フォーラム
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] Origin of the superiority of white matter reference region2018

    • Author(s)
      Kameyama, M., Ishibashi, K., Toyohara, J., Tokumaru, Aya M. Ishii, K.
    • Organizer
      Alzheimer Imaging Consortium 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] 未治療パーキンソン病における脳内代謝型グルタミン酸受容体1型密度-[C-11]ITMM PET研究-2018

    • Author(s)
      三品雅洋、鈴木正彦、石井賢二、石橋賢士、坂田宗之、我妻慧、豊原潤、張明栄、石渡喜一、木村和美
    • Organizer
      第12回パーキンソン病・運動障害疾患コングレス
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] Recovery from spatial memory deficits and increase of cerebral glucose uptake in cilostazol-administered aged mice2018

    • Author(s)
      柳井修一、多胡哲郎、豊原潤、新崎智子、遠藤昌吾
    • Organizer
      第41回日本基礎老化学会大会
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] PDE3阻害剤シロスタゾールの投与が老齢マウスの記憶機能改善と糖代謝亢進に及ぼす効果2018

    • Author(s)
      柳井修一、多胡哲郎、豊原潤、新崎智子、遠藤昌吾
    • Organizer
      第41回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] Radiosynthesis and preliminary biological evaluation of a 18F-labeled probe for histone deacetylase 6 PET imaging2018

    • Author(s)
      Tago, T., Toyohara, J., Ishii, K.
    • Organizer
      The 10th China-Japan-Korea Symposium on Radiopharmaceutical Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] Short-term follow-up of type 1 metabotropic glutamate receptor availability in patients with spinocerebellar ataxia type 62018

    • Author(s)
      Ishibashi, K., Miura, Y., Wagatsuma, K., Toyohara, J., Ishii, K.
    • Organizer
      Society for Neuroscience Annual Meeting 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] Metabotropic glutamate receptor subtype 1 PET imaging in medial temporal lobe epilepsy patients with hippocampal sclerosis2018

    • Author(s)
      Inaji, M., Nariai, T., Hayashi, S., Wagatsuma, K., Toyohara, J., Ishii, K., Maehara, T.
    • Organizer
      WFNMB 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] Efficacy of 4’-[methyl-11C]thiothymidine PET/CT before and after neoadjuvant therapy for predicting therapeutic responses in patients with esophageal cancer2018

    • Author(s)
      Hotta, M., Minamimoto, R., Yamada, K., Souma, D., Yokoyama, K., Toyohara, J., Takase, K.
    • Organizer
      64th Annual Meeting, Society of Nuclear Medicine and Molecular Imaging
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] Optimization of reconstruction conditions for tau PET imaging using [18F]THK53512018

    • Author(s)
      Wagatsuma, K., Miwa, K., Sakata, M., Ishibashi, K., Oda, K., Tago, T., Toyohara, J., Ishii, K.
    • Organizer
      WFNMB 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] Development of amyloid-β imaging ligands with a 18F-labeled neopentyl side-chain2018

    • Author(s)
      多胡哲郎、藤牧諒、豊原潤、平野圭市、岩井久美子、石橋賢士、田中浩士
    • Organizer
      第58回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] SCA6における代謝型グルタミン酸受容体1型の経時的変化2018

    • Author(s)
      石橋賢士、三浦義治、我妻慧、豊原潤、石井賢二
    • Organizer
      第58回日本核医学回学術総会
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] Preliminary biological evaluation of radioligands for PET imaging of histone deacetylase 62018

    • Author(s)
      Tago, T., Toyohara, J., Ishii, K.
    • Organizer
      EANM’18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] ネオペンチル標識基を有する18F-標識アミロイド-βプローブの性能評価2018

    • Author(s)
      多胡哲郎、豊原潤、藤牧諒、田中浩士、石井賢二
    • Organizer
      第13回日本分子イメージング学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] Fully automated radiosynthesis of [18F]MC225 for clinical use2018

    • Author(s)
      Toyohara, J., Tago, T., Colabufo, N.A., Luurtsema, G.
    • Organizer
      第58回日本核医学回学術総会
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] 施設認証の必要項目の詳細(1)PET薬剤の製造の基礎2018

    • Author(s)
      豊原潤
    • Organizer
      第18回日本核医学会春季大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] Biological Evaluation Of Novel 18F-labeled Beta-amyloid Probes With A Neopentyl Labeling Group2018

    • Author(s)
      Toyohara, J., Tago, T., Fujimaki, R., Hirano, K., Iwai, K., Tanaka, H.
    • Organizer
      EANM’18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] Isomeric [11C]methoxy analogs of nimesulide: radiosynthesis and in/ex vivo evaluation2018

    • Author(s)
      山本由美、多胡哲郎、豊原潤、齋藤陽平、山本文彦
    • Organizer
      第58回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] Automated radiosynthesis and biodistribuion of fluorine-18 labelled D-allose2018

    • Author(s)
      Yamamoto, H., Toyohara, J., Tago, T., Ibaraki, M., Kinoshita, T.
    • Organizer
      WFNMB 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] Fully automated radiosynthesis and preclinical toxicity studies of [18F]MC225 for clinical use2018

    • Author(s)
      Toyohara, J,, Tago, T., Colabufo, N.A., Luurtsema, G.
    • Organizer
      The 10th China-Japan-Korea Symposium on Radiopharmaceutical Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] Correlation of 11C-4DST uptake with isocitrate dehydrogenase 1 mutation in patients with glioma in comparison with 18F-FLT uptake.2018

    • Author(s)
      Yamamoto, Y., Takami, Y., Norikane, T., Toyohara, J., Nishiyama, Y.
    • Organizer
      RSNA2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] Volume estimation of radio-activated material in inner concrete walls of a cyclotron room at a PET research facility2018

    • Author(s)
      Wagatsuma, K., Kunugi, M., Miwa, K., Oda, K., Toyohara, J., Ishii, K.
    • Organizer
      64th Annual Meeting, Society of Nuclear Medicine and Molecular Imaging
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] Pre-discard estimation of radio-activated materials in the PET cyclotron systems of TMIG2018

    • Author(s)
      Wagatsuma, K., Kunugi, M., Oda, K., Miwa, K., Toyohara, J., Ishii, K.
    • Organizer
      第58回日本核医学回学術総会
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] Type 1 metabotropic glutamate receptors measured with a novel PET ligand, 11C-ITMM, in patients with cerebellar ataxia2018

    • Author(s)
      Ishibashi, K., Tago, T., Wagatsuma, K., Sakata, M., Toyohara, J., Ishii, K.
    • Organizer
      64th Annual Meeting, Society of Nuclear Medicine and Molecular Imaging
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] Glia imaging with 18F-THK5351 as a potential marker for neurodegeneration2018

    • Author(s)
      Ishii, K., Tago, T., Ishibashi, K., Wagatsuma, K., Sakata, M., Toyohara, J., Sengoku, R., Kanemaru, K., Murayama, S.
    • Organizer
      Alzheimer Imaging Consortium 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] Imaging Cellular Proliferation by Using [Methyl-11C]-4’-Thiothymidine: Great Idea but Tough Reality.2018

    • Author(s)
      Toyohara, J.
    • Organizer
      2018 Annual Meeting, Taiwanese Society of Medical Cyclotron
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07658
  • [Presentation] 脳機能イメージングのための新規PETトレーサーの開発とその臨床応用2017

    • Author(s)
      坂田宗之, 多胡哲郎, 我妻慧, 石橋賢士, 豊原潤, 石井賢二
    • Organizer
      第6回TOBIRA研究交流フォーラム
    • Data Source
      KAKENHI-PROJECT-16H05396
  • [Presentation] Imaging of adenosine A2A receptors in a healthy human brain by positron emission tomography with [11C]preladenant.2017

    • Author(s)
      Toyohara J, Sakata M, Ishibashi K, Wagatsuma K, Ishii K, Zhou X, de Vries EFJ, Elsinga PH, Ishiwata K.
    • Organizer
      Molecular imaging agents in medicine
    • Place of Presentation
      Groningen (The Netherlands)
    • Year and Date
      2017-02-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] 脳機能イメージングのための新規PETトレーサーの開発2017

    • Author(s)
      豊原潤
    • Organizer
      Neurovascular Unit 研究会
    • Place of Presentation
      慶應義塾大学医学部(東京都-信濃町)
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] 脳機能イメージングのための新規PETトレーサーの開発2017

    • Author(s)
      豊原潤
    • Organizer
      Neurovascular Unit 研究会
    • Place of Presentation
      信濃町
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05396
  • [Presentation] Is tau accumulation detectable before neuronal injury markers? Analysis from tau PET imaging with [C-11]PBB3 in clinical variations of Alzheimer’s disease.2017

    • Author(s)
      Imai M, Ishii K, Tanaka M, Ishibashi K, Wagatsuma K, Tago T, Toyohara J, Maruno H, Murayama S, Shimada H, Higuchi M, Suhara T.
    • Organizer
      Human Amyloid Imaging 2017
    • Place of Presentation
      Miami Beach (USA)
    • Year and Date
      2017-01-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] Imaging of adenosine A2A receptors in a healthy human brain by positron emission tomography with [11C]preladenant2017

    • Author(s)
      Toyohara, J., Sakata, M., Ishibashi, K., Wagatsuma, K., Ishii, K., Zhou, X., de Vries, E.F.J., Elsinga, P.H., Ishiwata, K.
    • Organizer
      Molecular imaging agents in medicine
    • Place of Presentation
      Groningen
    • Year and Date
      2017-02-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05396
  • [Presentation] エオジン好性核内封入体病における機能画像・髄液バイオマーカーの検討2016

    • Author(s)
      仙石錬平、渋川茉莉、本山りえ、森本悟、砂川昌子、金田大太、仁科裕史、豊原潤、藤ヶ崎純子、石井賢二、金丸和富、村山繁雄
    • Organizer
      第57回日本神経学会学術大会
    • Place of Presentation
      神戸コンベンションセンター(兵庫県-神戸市)
    • Year and Date
      2016-05-18
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] [C-11]ITMM PETを用いた未治療パーキンソン病における代謝型グルタミン酸受容体1型密度の検討―第一報―2016

    • Author(s)
      三品雅洋、鈴木正彦、石井賢二、坂田宗之、我妻慧、石橋賢士、豊原潤、張明栄、木村和美、石渡喜一
    • Organizer
      第56回日本核医学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県-名古屋市)
    • Year and Date
      2016-11-03
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] Regional cerebral blood flow following a single bout aerobic exercise: PET and TCD studies.2016

    • Author(s)
      Muta A, Hiura M, Nariai T, Maehara T, Sakata M. Oda K, Toyohara J, Ishiwata K, Ishii K.
    • Organizer
      OHBM 2016 Annual Meeting
    • Place of Presentation
      Geneva (Switzerland)
    • Year and Date
      2016-06-26
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] [18F]FBPA注射液の製造法の改善検討2016

    • Author(s)
      林薫平、酒井昌成、石渡喜一、渡辺利光、フランシスコゲラ、豊原潤
    • Organizer
      第56回日本核医学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県-名古屋市)
    • Year and Date
      2016-11-03
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] 消化管癌における11C-4DST PETと18F-FDG PETの比較2016

    • Author(s)
      安賀文俊、福田有子、山本由佳、田中賢一、小野優子、山本浩之、豊原潤、西山佳宏
    • Organizer
      第56回日本核医学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県-名古屋市)
    • Year and Date
      2016-11-03
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] 11C-4DSTと18F-FDGにおける食道癌の描出能に関する比較検討2016

    • Author(s)
      堀田昌利、南本亮吾、豊原潤、諸岡都、亀山征史、中島和彦、野原京子、山田和彦、窪田和雄
    • Organizer
      第56回日本核医学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県-名古屋市)
    • Year and Date
      2016-11-03
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] Clinical impact of amyloid PET with [C-11]Pittsburgh Compound B on the diagnosis of early onset dementias.2016

    • Author(s)
      Ishii K, Ishibashi K, Sakata M, Wagatsuma K, Toyohara J, Murayama S.
    • Organizer
      AAIC2016 Alzheimer’s Association International Conference
    • Place of Presentation
      Tronto (Canada)
    • Year and Date
      2016-07-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] Correlation of intratumor textual heterogeneity on 4'-[methyl-11C]thiothymidine PET/CT with Ki-67 immunohistochemistry and tumor grade in patients with newly diagnosed gliomas.2016

    • Author(s)
      Yamamoto Y, Mitamura K, Maeda Y, Hatakeyama T, Yamamoto H, Kudomi N, Toyohara J, Nishiyama Y.
    • Organizer
      SNMMI 2016 Annual Meeting
    • Place of Presentation
      San Diego (USA)
    • Year and Date
      2016-06-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] 新規アデノシンA2A受容体イメージング剤11C-preladenantの初期臨床評価2016

    • Author(s)
      豊原潤、坂田宗之、石橋賢士、我妻慧、周小云、ドフリースエリク、エルシンガフィリップ、石渡喜一、石井賢二
    • Organizer
      第56回日本核医学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2016-11-03
    • Data Source
      KAKENHI-PROJECT-16H05396
  • [Presentation] 孤発性脊髄小脳変性症における代謝型グルタミン酸受容体1型イメージング2016

    • Author(s)
      石橋賢士、三浦義治、石川欽也、張明栄、豊原潤、石渡喜一、石井賢二
    • Organizer
      第56回日本核医学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県-名古屋市)
    • Year and Date
      2016-11-03
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] 治療前神経膠腫における11C-4DST PETと造影MRIの比較2016

    • Author(s)
      福田有子、田中賢一、山本由佳、則兼敬志、畠山哲宗、山本浩之、久富信之、豊原潤
    • Organizer
      第56回日本核医学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県-名古屋市)
    • Year and Date
      2016-11-03
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] 4'-[methyl-11C]thiothymidine positron emission tomography in patients with newly diagnosed glioma.2016

    • Author(s)
      Fukuda Y, Tanaka K, Yamamoto Y, Hatakeyama T, Kudomi N, Toyohara J, Nishiyama Y.
    • Organizer
      EANM'16
    • Place of Presentation
      Barcelona (Spain)
    • Year and Date
      2016-10-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] First-in-human studies of imidazopyridineacetamide, [11C]CB184, as a novel 18 kDa translocator protein seeker.2016

    • Author(s)
      Toyohara J, Sakata M, Ishibashi K, Wagatsuma K, Hatano K, Ishiwata K, Ishii K.
    • Organizer
      EANM'16
    • Place of Presentation
      Barcelona (Spain)
    • Year and Date
      2016-10-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] 新規アデノシンA2A受容体イメージング剤11C-Preladenantの初期臨床評価2016

    • Author(s)
      豊原潤、坂田宗之、石橋賢士、我妻慧、周小云、ドフリースエリク、エルシンガフィリップ、石渡喜一、石井賢二
    • Organizer
      第56回日本核医学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県-名古屋市)
    • Year and Date
      2016-11-03
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] 脳卒中慢性期における有酸素運動が脳血流量とμオピオイド受容体に及ぼす影響; 至適運動療法の検討2016

    • Author(s)
      日浦幹夫、成相直、石井賢二、坂田宗之、豊原潤、織田圭一、石渡喜一
    • Organizer
      第41回日本脳卒中学会総会
    • Place of Presentation
      ロイトン札幌(北海道-札幌市)
    • Year and Date
      2016-04-14
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] Preclinical and first-in-man studies of imidazopyridine acetamide, [11C]CB184, as a novel 18 kDa translator protein seeker.2016

    • Author(s)
      Toyohara J, Sakata M, Ishibashi K, Wagatsuma K, Hatano K, Yanai S, Endo S, Ishii K, and Ishiwata K.
    • Organizer
      SNMMI 2016 Annual Meeting
    • Place of Presentation
      Sandiego
    • Year and Date
      2016-06-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] 脳FDG画像を用いた認知症鑑別診断における機械学習から得られる画像指標と認知機能との関係2016

    • Author(s)
      坂田宗之、王小宇、石井賢二、木村裕一、我妻慧、石橋賢士、豊原潤、矢田紀子、眞鍋佳嗣
    • Organizer
      第56回日本核医学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県-名古屋市)
    • Year and Date
      2016-11-03
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] PETイメージングを活用した運動負荷時の脳機能解析:脳血流と神経受容体計測の実際2016

    • Author(s)
      日浦幹夫、成相直、牟田光孝、稲次基希、豊原潤、石井賢二、石橋賢士、我妻慧、坂田宗之、織田圭一、石渡喜一、前原健寿
    • Organizer
      第59回日本脳循環代謝学会学術総会
    • Place of Presentation
      あわぎんホール(徳島県-徳島市)
    • Year and Date
      2016-11-11
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] Density of metabotropic glutamate receptors subtype 1 in de novo patients with Parkinson’s disease using 11C-ITMM PET.2016

    • Author(s)
      Mishina M, Suzuki M, Ishii K, Sakata M, Wagatsuma K, Ishibashi K, Toyohara J, Zhang MR, Kimura K, Ishiwata K.
    • Organizer
      The MDS 20th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      Berlin (Germany)
    • Year and Date
      2016-06-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] PET薬剤製造の基礎-アミロイドPET薬剤等を作るために必要な知識-2016

    • Author(s)
      豊原潤
    • Organizer
      第16回日本核医学会春季大会
    • Place of Presentation
      大阪国際交流センター(大阪府-大阪市)
    • Year and Date
      2016-04-23
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] Preclinical and a first-in man studes on [11C]CB184 for imaging 18 kDa translocator protein by positron emission tomography.2016

    • Author(s)
      Toyohara J, Sakata M, Ishibashi K, Wagatsuma K, Hatano K, Yanai S, Endo S, Ishii K, Ishiwata K.
    • Organizer
      SNMMI 2016 Annual Meeting
    • Place of Presentation
      San Diego (USA)
    • Year and Date
      2016-06-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] 新規TSPOイメージング剤11C-CB184の初期臨床評価2016

    • Author(s)
      豊原潤、坂田宗之、石橋賢士、我妻慧、籏野健太郎、石渡喜一、石井賢二
    • Organizer
      第56回日本核医学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県-名古屋市)
    • Year and Date
      2016-11-03
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] mGluR1 PET imaging of mTLE patients with HS2016

    • Author(s)
      Inaji M, Hayashi S, Nariai T, Wagatsuma K, Toyohara J, Ishii K, Maehara T.
    • Organizer
      第50回日本てんかん学会学術集会
    • Place of Presentation
      グランシップ(静岡県-静岡市)
    • Year and Date
      2016-10-07
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] 臨床応用を目指したPET薬剤の次世代化2016

    • Author(s)
      豊原潤、多湖哲郎、坂田宗之、石橋賢士、我妻慧、石渡喜一、石井賢二
    • Organizer
      第56回日本核医学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県-名古屋市)
    • Year and Date
      2016-11-03
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] Prognostic value of 4'-[methyl-11C]-thiothymidine PET in a patients with newly diagnosed glioma.2016

    • Author(s)
      Yamamoto Y, Tanaka K, Mitamura K, Norikane T, Fukuda Y, Hatakeyama T, Yamamoto H, Toyohara J, Nishiyama Y.
    • Organizer
      EANM'16
    • Place of Presentation
      Barcelona (Spain)
    • Year and Date
      2016-10-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] mGluR1 PET imaging in medial temporal lobe epilepsy patients with hippocampal sclerosis.2016

    • Author(s)
      Inaji M, Hayashi S, Nariai T, Wagatsuma K、Toyohara J, Ishii K, Maehara T.
    • Organizer
      AES annual meeting
    • Place of Presentation
      Philadelphia (USA)
    • Year and Date
      2016-12-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] Prospective comparison of 11C-4DST, 18F-FDG PET/CT and whole-body MRI in the patients with multile myeloma.2016

    • Author(s)
      Minamimoto R, Toyohara J, Okasaki M, Morooka M, Miyata Y, Kameyama M, Hotta M, Nakajima K, Miwa A, Kubota K.
    • Organizer
      SNMMI 2016 Annual Meeting
    • Place of Presentation
      San Diego (USA)
    • Year and Date
      2016-06-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] 臨床応用を目指したPET薬剤の次世代化2016

    • Author(s)
      豊原潤、多湖哲郎、坂田宗之、石橋賢士、我妻慧、石渡喜一、石井賢二:臨床応用を目指したPET薬剤の次世代化
    • Organizer
      第56回日本核医学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2016-11-03
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05396
  • [Presentation] 頭頸部癌の放射線化学療法前後における11C-4DST PETと18F-FDG PETの比較2016

    • Author(s)
      三田村克哉、山本由佳、則兼敬志、星川広史、豊原潤、西山佳宏
    • Organizer
      第56回日本核医学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県-名古屋市)
    • Year and Date
      2016-11-03
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] 基礎研究と臨床研究は両立できる2016

    • Author(s)
      豊原潤
    • Organizer
      PETサマーセミナー2016
    • Place of Presentation
      ANAクラウンプラザホテル熊本ニュースカイ(熊本県-熊本市)
    • Year and Date
      2016-08-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] Changes of metabotropic glutamate receptor type 1 binding of [11C]ITMM by aging.2015

    • Author(s)
      Sakata M., Toyohara J., Wagatsuma K., Ishibashi K., Ishii K., Zhang M-R., Ishiwata K.
    • Organizer
      12th International Conference on Quantification of Brain Function with PET (BrainPET 2015)
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2015-06-27
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24390298
  • [Presentation] 細胞増殖能イメージングトレーサー(がん)2015

    • Author(s)
      豊原潤
    • Organizer
      PETサマーセミナー2015 in 東京ベイ
    • Place of Presentation
      舞浜(千葉)
    • Year and Date
      2015-09-04
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] [18F:Flutemetamol製造施設認証に必要な条件:TMIGのケース2015

    • Author(s)
      豊原潤
    • Organizer
      PETサマーセミナー2015 in 東京ベイ
    • Place of Presentation
      舞浜(千葉)
    • Year and Date
      2015-09-04
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] 代謝型グルタミン酸受容体タイプ1の加齢変化&#8212;[11C]ITMM-PETを用いた検討2015

    • Author(s)
      坂田宗之、豊原潤、我妻慧、石橋賢士、石井賢二、張明栄、石渡喜一
    • Organizer
      第38回基礎老化学会大会
    • Place of Presentation
      横浜
    • Year and Date
      2015-06-13
    • Data Source
      KAKENHI-PROJECT-24390298
  • [Presentation] (R)-[11C]emopamil as a novel tracer for imaging enhanced P^glycoprotein function in the brain.2015

    • Author(s)
      Toyohara J, Okamoto M, Aramaki H, Zaitsu Y, Shimizu I, Hosokawa S, and Ishiwata K.
    • Organizer
      EANM'15
    • Place of Presentation
      Hamburg (Germany)
    • Year and Date
      2015-10-10
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] Correlation of 11C-4DST and 11C-MET uptake on PET with tumor grade and Ki-67 immunohistochemistry in patients with newly diagnosed gliomas2015

    • Author(s)
      Kenichi Tanaka, Yuka Yamamoto, Tetsuhiro Hatakeyama, Hiroyuki Yamamoto, Jun Toyohara, Yoshihiro Nishiyama
    • Organizer
      SNMMI 2015 Annual Meeting
    • Place of Presentation
      Baltimore
    • Year and Date
      2015-06-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25461828
  • [Presentation] Correlation of 11C-4DST uptake on PET with Ki-67 immunohistochemistry in patients with newly diagnosed and recurrent gliomas2015

    • Author(s)
      Yuka Yamamoto, Kenichi Tanaka, Tetsuhiro Hatakeyama, Hiroyuki Yamamoto, Jun Toyohara, Yoshihiro Nishiyama
    • Organizer
      SNMMI 2015 Annual Meeting
    • Place of Presentation
      Baltimore
    • Year and Date
      2015-06-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25461828
  • [Presentation] PET薬剤製造の基礎ーFDG以外の薬剤を作るために必要な基礎知識ー2015

    • Author(s)
      豊原潤
    • Organizer
      第15回日本核医学会春季大会
    • Place of Presentation
      船堀(東京)
    • Year and Date
      2015-04-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] Correlation of 11C-4DST and 11C-MET uptake on Pet with tumor grade and Ki-67 immunohistochemistry in patients with newly diagnosed gliomas.2015

    • Author(s)
      Tanaka K, Yamamoto Y, Hatakeyama T, Yamamoto H, Toyohara J, and Nishiyama Y.
    • Organizer
      SNMMI 2015 Annual Meeting
    • Place of Presentation
      Baltimore (USA)
    • Year and Date
      2015-06-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] 7alpha-(3-[18F]fluoropropyl)testosteroneの開発2015

    • Author(s)
      中喬介、清水功雄、岡本真由美、石渡喜一、豊原潤
    • Organizer
      第15回放射性医薬品・画像診断薬研究会
    • Place of Presentation
      京都(京都)
    • Year and Date
      2015-09-12
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] [11C]ITMMによる代謝型グルタミン酸受容体1結合能の加齢変化2015

    • Author(s)
      坂田宗之、豊原潤、我妻慧、石橋賢士、石井賢二、張明栄、石渡喜一
    • Organizer
      第55回日本核医学会学術総会
    • Place of Presentation
      東京
    • Year and Date
      2015-11-05
    • Data Source
      KAKENHI-PROJECT-24390298
  • [Presentation] Differential alteration of neuronal network with FDG-PET in Alzheimer's disease and dementia with Lewy bodies.2015

    • Author(s)
      Yamamoto Y, Tanaka K, Hatakeyama T, Yamamoto H, Toyohara J, Murano H, and Ishii K.
    • Organizer
      SNMMI 2015 Annual Meeting
    • Place of Presentation
      Baltimore (USA)
    • Year and Date
      2015-06-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] Structure activity relationships of 18F-labeled 7alpha-alkyl-estradiol derivatives.2015

    • Author(s)
      Toyohara J, Okamoto M, Shibayama H, Naka K, Kitagawa Y, Ishiwata K, and Shimizu I.
    • Organizer
      ISRS 2015
    • Place of Presentation
      Missouri (USA)
    • Year and Date
      2015-05-26
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] P糖たんぱく質の機能亢進を画像化するPET薬剤としての(R)-[11C]emopamilの基礎評価2015

    • Author(s)
      豊原潤、岡本真由美、荒牧光紀、財津優人、清水功雄、石渡喜一
    • Organizer
      第55回日本核医学会学術総会
    • Place of Presentation
      新宿(東京)
    • Year and Date
      2015-11-05
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] (R)-[11C]emopamil as a novel tracer for imaging enhanced P-glycoprotein function.2015

    • Author(s)
      Toyohara J, Aramaki H, Zaitsu Y, Okamoto M, Hosokawa S, Shimizu I, and Ishiwata K.
    • Organizer
      JCSRC2015
    • Place of Presentation
      Chiba (Japan)
    • Year and Date
      2015-11-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] Comparison of 4DST and FDG PET/CT imaging for advanced clear cell renal cell carcinoma.2015

    • Author(s)
      MInamimoto R, Nakaigawa N, Toyohara J, Nagashima Y, Miata Y, Okazaki M, Morooka M, Nakajima K, Sunaoka F, and Kubota K.
    • Organizer
      SNMMI 2015 Annual Meeting
    • Place of Presentation
      Baltimore (USA)
    • Year and Date
      2015-06-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] ヒトを対象としたPET分子イメージング2014

    • Author(s)
      豊原潤
    • Organizer
      第58回日本薬学会関東支部大会
    • Place of Presentation
      町田
    • Year and Date
      2014-10-04
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] 光学活性11C-Emopamilの標識合成と基礎評価2014

    • Author(s)
      荒牧光紀、財津優人、岡本真由美、清水功雄、石渡喜一、豊原潤
    • Organizer
      第14回放射性医薬品・画像診断薬研究会
    • Place of Presentation
      京都
    • Year and Date
      2014-09-13
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] 7α-[18F]Estradiolの構造活性相関研究2014

    • Author(s)
      芝山啓允、中喬介、北川雄也、岡本真由美、豊原潤、石渡喜一、清水功雄
    • Organizer
      第14回放射性医薬品・画像診断薬研究会
    • Place of Presentation
      京都
    • Year and Date
      2014-09-13
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] Imaging of DNA synthesis rate of malignant brain tumor with newly developed PET molecular imaging probe 11C-4DST2013

    • Author(s)
      Inaji, M., Nariai, T., Tanaka, Y., Oda, K., Sakata, M., Toyohara, J., Ishii, K., Ishiwata, K., Maehara, T. and Ohno, K
    • Organizer
      Joint Neurosurgical Convention 2013 (the 6th International Mt. Bandai Symposium for Neuroscience and the 7th Pan-Pacific Neurosurgery Congress)
    • Place of Presentation
      Hawaii
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Presentation] Diagnostic and prognostic value of nodal staging by 4'-[methyl-11C]-thiothymidine (4DST) PET/CT in non small cell lung cancer.2013

    • Author(s)
      Minamimoto R, Ishiwata K, Nakajima K, Okazaki M, Miyata Y, Morooka M, Toyohara J and Kubota K
    • Organizer
      99th Scientific Assembly and Annual Meeting of Radiological Society of North America
    • Place of Presentation
      Chicago
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] FDG以外の腫瘍PETイメージングプローブ2013

    • Author(s)
      豊原潤
    • Organizer
      第7回四国 PET 勉強会
    • Place of Presentation
      高松
    • Invited
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Presentation] FDG以外の腫瘍PETイメージングプローブ2013

    • Author(s)
      豊原潤
    • Organizer
      第7回四国PET勉強会
    • Place of Presentation
      高松
    • Year and Date
      2013-03-16
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Presentation] Synthesis and evaluation of a fluorine-18-labeled 7α-(3-fluoropropyl)estradiol2013

    • Author(s)
      Okamoto, M., Matsui, A., Kitagawa, Y., Toyohara, J., Ishiwata, K., Yoshimoto, M. and Shimizu, I
    • Place of Presentation
      Jeju
    • Data Source
      KAKENHI-PROJECT-23659605
  • [Presentation] Synthesis and evaluation of a fluorine-18-labeled 7a-(3-fluoropropyl)estradiol.2013

    • Author(s)
      Okamoto, M.,Matsui, A., Kitagawa, Y., Toyohara, J., Ishiwata, K., Yoshimoto, M. and Shimizu, I.
    • Organizer
      20th International Symposium on Radiopharmaceutical Sciences
    • Place of Presentation
      Jeju
    • Data Source
      KAKENHI-PROJECT-23659605
  • [Presentation] The potential of proliferation imaging by 4'-[methyl-11C]thiothymidine (4DST) PET/CT for nodal staging of non-small cell lung cancer.2013

    • Author(s)
      Minamimoto R, Toyohara J, Morooka M, Miyata Y, Okasaki M, Nakajima K, Mitsumoto T, Sunaoka F, Ishiwata K and Kubota K
    • Organizer
      60th Annual Meeting of the Society of Nuclear Medicine
    • Place of Presentation
      Vancouver
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] 11C-4DSTを用いたDNA合成の分子イメージング2013

    • Author(s)
      豊原潤
    • Organizer
      第72回日本医学放射線学会総会
    • Place of Presentation
      横浜
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] Initial evaluation of [11C]ITMM for mapping metabotropic glutamate receptor type 1 in human brain.2013

    • Author(s)
      Sakata, M., Toyohara, J., Oda, K., Ishii, K. Zhang, MR., Ishiwata, K.
    • Organizer
      11th International Conference on Quantification of Brain Function with PET (BrainPET ’13)
    • Place of Presentation
      Syanghai
    • Data Source
      KAKENHI-PROJECT-24390298
  • [Presentation] 代謝型グルタミン酸受容体タイプ1リガンド[11C]ITMMのヒト脳PET計測2013

    • Author(s)
      坂田宗之、豊原潤、織田圭一、石井賢二、張明栄、石渡喜一
    • Organizer
      第53回日本核医学会学術総会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-24390298
  • [Presentation] PETプローブ開発の基礎2013

    • Author(s)
      豊原潤
    • Organizer
      PETサマーセミナー2013
    • Place of Presentation
      金沢
    • Invited
    • Data Source
      KAKENHI-PROJECT-23659605
  • [Presentation] PET プローブ開発の基礎2013

    • Author(s)
      豊原 潤
    • Organizer
      PETサマーセミナー2013
    • Place of Presentation
      金沢
    • Data Source
      KAKENHI-PROJECT-23659605
  • [Presentation] Imaging of DNA synthesis rate of malignant brain tumor with a newly developed PET molecular imaging probe 11C-4DST.2013

    • Author(s)
      Hayashi S, Inaji M, Nariai T, Tanaka Y, Maehara T, Oda K, Sakata M, Toyohara J, Ishiwata K and Ishii K
    • Organizer
      15th WFNS World Congress of Neurosurgery
    • Place of Presentation
      Seoul
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] 11C-4DST PETを用いた悪性脳腫瘍のDNA合性能評価法の検討2012

    • Author(s)
      成相直、稲次基希、豊原潤、石渡喜一、坂田宗之、石井賢二、織田圭一、田中洋次、青柳傑
    • Organizer
      第52回日本核医学会学術総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Presentation] 代謝型グルタミン酸受容体サブタイプ1リガンド^<11>C-ITMMの非臨床研究2012

    • Author(s)
      豊原潤、坂田宗之、ジェッケルクリスチナ、藤永雅之、張明栄、石渡喜一
    • Organizer
      第52回日本核医学会学術総会
    • Place of Presentation
      札幌
    • Year and Date
      2012-10-12
    • Data Source
      KAKENHI-PROJECT-24390298
  • [Presentation] Sigma receptors2012

    • Author(s)
      Toyohara J
    • Organizer
      International symposium on PET and SPECT in neurology and psychiatry
    • Place of Presentation
      Groningen
    • Data Source
      KAKENHI-PROJECT-23659605
  • [Presentation] DNA合成診断薬剤11C-4DSTによる肺癌リンパ節移転の検出能力に関する検討2012

    • Author(s)
      南本亮吾、窪田和雄、豊原潤、伊藤秀幸、諸岡都、岡崎百子、宮田陽子、中島和彦、伊藤公輝、三本拓也、石渡喜一
    • Organizer
      第52回日本核医学会学術総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Presentation] 新規PET薬剤開発からfirst-in-human studyまで-多施設共同研究への取り組み2012

    • Author(s)
      豊原潤、坂田宗之、織田圭一、石井賢二、石渡喜一
    • Organizer
      第52回日本核医学会学術総会
    • Place of Presentation
      札幌
    • Year and Date
      2012-10-11
    • Data Source
      KAKENHI-PROJECT-24390298
  • [Presentation] 新規PET薬剤からfirst-in-human studyまで-多施設共同研究への取り組み-2012

    • Author(s)
      豊原潤
    • Organizer
      第52回日本核医学会学術総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Presentation] 新規PET薬剤開発からfirst-in-human studyまでー多施設共同研究への取り組みー2012

    • Author(s)
      豊原潤、坂田宗之、織田圭一、石井賢二、石渡喜一
    • Organizer
      第52回日本核医学会学術総会
    • Place of Presentation
      札幌
    • Invited
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Presentation] Proliferation imaging by 11C-4DST PET/CT for differentiation of malignant and benign lesion2012

    • Author(s)
      Minamimoto, R., Toyohara, J., Morooka, M., Okasaki, M., Ito, K., Miyata, Y., Mitsumoto, T., Nakajima, K. and Kubota, K.
    • Organizer
      59th Annual Meeting of the Society of Nuclear Medicine
    • Place of Presentation
      Miami Beach
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Presentation] ^<11>C-4DSTの炎症集積に関する検討2012

    • Author(s)
      豊原潤
    • Organizer
      第52回日本核医学会学術総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Presentation] 11C-4DST PETを用いたDNA合成能イメージングによる悪性脳腫瘍診断2012

    • Author(s)
      稲次基希、成相直、田中洋次、坂田宗之、豊原潤、石渡喜一、石井賢二、青柳傑
    • Organizer
      第13回日本分子脳神経外科学会
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Presentation] DNA合成の分子イメージングー4DST研究の現状と展望ー2012

    • Author(s)
      豊原潤
    • Organizer
      第77回日本核医学会関東甲信越地方会
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Presentation] A molecular imaging study of multiple myeloma: Comparison of 18F-FDG, 11C-methionine (MET), and 11C-thiothymidine (4DST) PET2012

    • Author(s)
      Okasaki, M., Kubota, K., Minamimoto, R., Morooka, M., Miyata, Y., Ito, K., Toyohara, J., Ishiwata, K., Hirai, R. and Miwa, A.
    • Organizer
      59th Annual Meeting of the Society of Nuclear Medicine
    • Place of Presentation
      Miami Beach
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Presentation] DNA合成の分子イメージング-4DST研究の現状と展望-2012

    • Author(s)
      豊原潤
    • Organizer
      第77回日本核医学会関東甲信越地方会
    • Place of Presentation
      東京
    • Year and Date
      2012-07-14
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Presentation] 新規PET 薬剤開発からfirst-in-human study まで―多施設共同研究への取り組み―2012

    • Author(s)
      豊原 潤、坂田宗之、織田圭一、石井賢二、石渡喜一
    • Organizer
      第52回日本核医学会学術総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23659605
  • [Presentation] 新規PET薬剤開発からfirst-in-human studyまでー多施設共同研究への取り組みー2012

    • Author(s)
      豊原潤、坂田宗之、織田圭一、石井賢二、石渡喜一
    • Organizer
      第52回日本核医学会学術総会
    • Place of Presentation
      札幌
    • Invited
    • Data Source
      KAKENHI-PROJECT-23659605
  • [Presentation] 化学薬学セッションPET薬剤の理解のためにーPET医師のための化学薬学の時間ー2012

    • Author(s)
      豊原潤
    • Organizer
      PETサマーセミナー2012
    • Place of Presentation
      松本
    • Invited
    • Data Source
      KAKENHI-PROJECT-23659605
  • [Presentation] Dose sigma1 ligand [^<11>C]SA4503 bind to the emopamil binding protein in the brain in vivo?2012

    • Author(s)
      Toyohara, J., Sakata, M. and Ishiwata, K
    • Organizer
      The 9th international symposium on fuctional neuroreceptor mapping of the living brain
    • Place of Presentation
      Baltimore
    • Data Source
      KAKENHI-PROJECT-23659605
  • [Presentation] 化学薬学セッション : PET 薬剤の理解のために―PET 医師のための化学薬学の時間―2012

    • Author(s)
      豊原 潤
    • Organizer
      PET サマーセミナー2012
    • Place of Presentation
      松本
    • Data Source
      KAKENHI-PROJECT-23659605
  • [Presentation] PET薬剤の被曝線量評価における小動物実験とヒト全身PETとの比較2012

    • Author(s)
      坂田宗之、織田圭一、豊原潤、石井賢二、石渡喜一
    • Organizer
      第52回日本核医学会学術総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Presentation] Clinical use of 4DST as a new PET molecular imaging probe to measure DNA synthesis of brain tumor2012

    • Author(s)
      Nariai, T., Inaji, M., Toyohara, J., Ishiwata, K., Tanaka, Y., Aoyagi, M. and Ohno, K.
    • Organizer
      The 4th International Symposium of Brain Tumor pathology
    • Place of Presentation
      Nagoya
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Presentation] Dose sigma1 ligand [11C]SA4503 bind to the emopamil binding protein in the brain in vivo?2012

    • Author(s)
      Toyohara, J., Sakata, M. and Ishiwata, K.
    • Organizer
      The 9th international symposium on functional neuroreceptor mapping of the living brain (NRM12)
    • Place of Presentation
      Baltimore
    • Data Source
      KAKENHI-PROJECT-23659605
  • [Presentation] 11C-4DSTの炎症集積に関する検討2012

    • Author(s)
      豊原潤、林薫平、石渡喜一
    • Organizer
      第52回日本核医学会学術総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Presentation] 代謝型グルタミン酸受容体サブタイプ1 (mGluRl)リガンド^<11>C-ITMMの初期臨床評価2012

    • Author(s)
      豊原潤、坂田宗之、伊藤公輝、日浦幹夫、織田圭一、石井賢二、張明栄、石渡喜一
    • Organizer
      第12回放射性医薬品・画像診断薬研究会
    • Place of Presentation
      京都
    • Year and Date
      2012-12-15
    • Data Source
      KAKENHI-PROJECT-24390298
  • [Presentation] Initial clinical trials of carbon-11-labeled 4DST in brain tumors2011

    • Author(s)
      Toyohara J
    • Organizer
      SNM 2011 Annual Meeting
    • Place of Presentation
      サンアントニオ(米国)
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Presentation] Kinetic modeling of [11C] 4DST PET imaging DNA synthesis rate. Initial clinical trials in brain tumors2011

    • Author(s)
      Sakata M, Toyohara J, Nariai T, et al.
    • Organizer
      25th International Symposium on Cerebral Blood Flow, Metabolism, and Function & 10th International Conference on Quantification of Brain Function with PET 2011
    • Place of Presentation
      Barcelona, Spain
    • Data Source
      KAKENHI-PROJECT-23390344
  • [Presentation] Initial clinical trials of carbon-11-labeled 4DST in brain tumors2011

    • Author(s)
      Toyohara, J.
    • Organizer
      58th Annual meeting of the society of nuclear medicine
    • Place of Presentation
      San Antonio (USA)
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Presentation] ^<11>C-4DST PETの腫瘍と炎症の鑑別診断に関する基礎的検討2011

    • Author(s)
      豊原潤
    • Organizer
      第51回目本核医学会学術総会、
    • Place of Presentation
      つくば市
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Presentation] 新規DNA合成診断薬剤^<11>C-4DSTの初期臨床評価-安全性評価と代謝分析2011

    • Author(s)
      豊原潤
    • Organizer
      第50回日本核医学会学術総会
    • Place of Presentation
      大宮
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Presentation] てびき第4版解説4チミジン[^<11>C]チオチミジン2011

    • Author(s)
      豊原潤
    • Organizer
      第20回PET化学ワークショップ
    • Place of Presentation
      湯沢町
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Presentation] Initial clinical trials of carbon-11-labeled 4DST in brain tumors2011

    • Author(s)
      Toyohara J, Nariai T, et al.
    • Organizer
      SNM 2011 Annual Meeting
    • Place of Presentation
      San Antonio, USA
    • Data Source
      KAKENHI-PROJECT-23390344
  • [Presentation] Evaluation of 4'-[methyl-^<11>C]thiothymidine in a rodent model of tumor and inflammation.2011

    • Author(s)
      Toyohara, J.
    • Organizer
      Annual congress of the European association of nuclear medicine
    • Place of Presentation
      Birmingham (UK)
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Presentation] Evaluation of 4'-[methyl-^<11>C]thiothymidine in a rodent model of tumor and inflammation2011

    • Author(s)
      Toyohara J
    • Organizer
      Annual Congress of the European Association of Nuclear Medicine (EANM'11)
    • Place of Presentation
      バーミンガム(英国)
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Presentation] ^<11>C-4DST PETの腫瘍と炎症の鑑別診断に関する基礎的検討2011

    • Author(s)
      豊原潤
    • Organizer
      第51回日本核医学会総会
    • Place of Presentation
      つくば
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Presentation] ^<11>C-4DST動態解析に関する基礎的検討2011

    • Author(s)
      豊原潤
    • Organizer
      第51回日本核医学会総会
    • Place of Presentation
      つくば
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Presentation] ^<11>C-4DST動態解析に関する基礎的検討2011

    • Author(s)
      豊原潤
    • Organizer
      第51回日本核医学会学術総会
    • Place of Presentation
      つくば市
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Presentation] 新規DNA合成診断薬剤^<11>C-4DSTの初期臨床評価悪性脳腫瘍への臨床応用2010

    • Author(s)
      成相直、豊原潤、坂田宗之、川邊拓也、織田圭一、窪田和雄、武川麻紀、大野喜久郎、石井賢二、石渡喜一
    • Organizer
      第50回日本核医学会学術総会
    • Place of Presentation
      大宮市
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Presentation] シンポジウム画像診断の進歩と展望悪性脳腫瘍に対するPETマルチトレーサーイメージングの臨床活用-新しいDNA合成イメージング法の採用による今後の展望-2010

    • Author(s)
      成相直、田中洋次、稲次基希、武川麻紀、百瀬俊也、川邊拓也、山本昌昭、窪田和雄、石渡喜一、豊原潤、大野喜久郎
    • Organizer
      第69回日本脳神経外科学会学術総会
    • Place of Presentation
      福岡市
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Presentation] 新規DNA合成診断薬剤^<11>C-4DSTの初期臨床評価安全性評価と代謝分析2010

    • Author(s)
      豊原潤、成相直、坂出宗之、川邊拓也、織田圭一、窪田和雄、諸岡都、石井賢二、石渡喜一
    • Organizer
      第50回日本核医学会学術総会
    • Place of Presentation
      大宮市
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Presentation] 新規DNA合成診断薬剤^<11>C-4DSTの初期臨床評価全身PET両像の評価2010

    • Author(s)
      窪田和雄、諸岡都、南本亮吾、伊藤公輝、宮田陽子、中島和彦、成相直、豊原潤、坂田宗之、石渡喜一
    • Organizer
      第50回日本核医学会学術総会
    • Place of Presentation
      大宮市
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Presentation] 新規DNA合成診断薬剤^<11>C-4DSTの初期臨床評価脳腫瘍での動態解析2010

    • Author(s)
      坂田宗之、豊原潤、成相直、川邊拓也、織田圭一、石井賢二、窪田和雄、石渡喜一
    • Organizer
      第50回日本核医学会学術総会
    • Place of Presentation
      大宮市
    • Data Source
      KAKENHI-PROJECT-22390241
  • [Presentation] [^<11>C]PIB脳内集積と髄液バイオマーカAβ1-42の関係2010

    • Author(s)
      石井賢二、金丸和富、滝本美咲、坂田宗之、織田圭一、豊原潤、村山繁雄、石渡喜一
    • Organizer
      第50回日本核医学会学術総会
    • Place of Presentation
      大宮市
    • Data Source
      KAKENHI-PROJECT-20390334
  • [Presentation] 悪性脳腫瘍に対するPETマルチトレーサーイメージングの臨床活用-新しいDNA合成イメージング法の採用による今後の展望-2010

    • Author(s)
      成相直、田中洋次、稲次基希、武川麻紀、百瀬俊也、川邊拓也、山本昌昭、窪田和雄、石渡喜一、豊原潤、大野喜久郎
    • Organizer
      第69回日本脳神経外科学会学術総会
    • Place of Presentation
      福岡市
    • Data Source
      KAKENHI-PROJECT-20390334
  • [Presentation] [11^C]PIB脳内集積と髄液バイオマーカAβ1-42の関係2010

    • Author(s)
      石井賢二、金丸和富、滝本美咲、坂田宗之、織田圭一、豊原潤、村山繁雄、石渡喜二
    • Organizer
      第50回日本核医学会学術総会
    • Place of Presentation
      大宮市
    • Data Source
      KAKENHI-PROJECT-20390334
  • [Presentation] 統合失調症患者における脳シグマ1受容体のPETによる測定2010

    • Author(s)
      石川雅智、坂田宗之、石井賢二、織田圭一、呉勁、豊原潤、木村祐一、伊豫雅臣、石渡喜一、橋本謙二
    • Organizer
      第3回精神神経系薬物治療研究報告会
    • Place of Presentation
      豊中市
    • Year and Date
      2010-12-03
    • Data Source
      KAKENHI-PROJECT-20390334
  • [Presentation] ストレス応答を標的とした腫瘍画像診断薬の開発2008

    • Author(s)
      豊原潤
    • Organizer
      第48回日本核医学会学術総会
    • Place of Presentation
      幕張
    • Year and Date
      2008-10-26
    • Data Source
      KAKENHI-PROJECT-19591445
  • [Presentation] ストレス応答を標的とした腫瘍画像診断薬の開発2008

    • Author(s)
      豊原潤
    • Organizer
      第48回日本核医学会総会
    • Place of Presentation
      幕張
    • Year and Date
      2008-10-26
    • Data Source
      KAKENHI-PROJECT-19591445
  • [Presentation] PET/CTを使用したMIRD法による実行線量評価

    • Author(s)
      伊藤公輝、坂田宗之、我妻慧、織田圭一、豊原潤、石橋賢士、石井賢二、石渡喜一
    • Organizer
      第54回日本核医学会学術総会
    • Place of Presentation
      大阪市
    • Year and Date
      2014-11-06 – 2014-11-08
    • Data Source
      KAKENHI-PROJECT-24390298
  • [Presentation] Evaluation of [11C]CB184 for imaging and quantification of neuroinflammation i n rat model of helped encephalitis

    • Author(s)
      Garcia DV, de Vries EJF, Hatano K, Toyohara J, Ishiwata K, Dierckx RAJO, Doorduin J
    • Organizer
      Annual Congress of the European Association of Nuclear Medicine
    • Place of Presentation
      Gothenburg
    • Year and Date
      2014-10-18 – 2014-10-22
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] Comparison of 4'-[methyl-11C]thiothymidine (4DST) and FDG PET/CT for early therapy monitoring of advanced non small cell lung cancer

    • Author(s)
      Minamimoto R, Toyohara J, Miyata Y, Okasaki M, Morooka M, Nakajima K, Ishiwata K, Kubota K
    • Organizer
      60th Annual Meeting, Society of Nuclear Medicine and Molecular Imaging
    • Place of Presentation
      St. Louis
    • Year and Date
      2014-06-07 – 2014-06-11
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] 11C-4DST PETのGlioma悪性度診断における有用性と妥当性の検証

    • Author(s)
      21.稲次基希、成相直、林志保里、田中洋次、織田圭一、坂田宗之、石渡喜一、豊原潤、石井賢二、前原健寿
    • Organizer
      第53回日本核医学会学術総会
    • Place of Presentation
      福岡国際会議場(福岡県福岡市)
    • Year and Date
      2013-11-08 – 2013-11-10
    • Data Source
      KAKENHI-PROJECT-23390344
  • [Presentation] 11C-4DST PET for proliferation imaging in patients with newly diagnosed high-grade gliomas: comparison with 18F-FLT PET

    • Author(s)
      Yamamoto Y, Kawai N, Yamamoto H, Maeda Y, Toyohara J, Nishiyama Y
    • Organizer
      60th Annual Meeting, Society of Nuclear Medicine and Molecular Imaging
    • Place of Presentation
      St. Louis
    • Year and Date
      2014-06-07 – 2014-06-11
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] 4'-[Methyl-11C]thiothymidine PET for proliferation imaging in head and neck squamous cell carcinoma: comparison with 18F-FDG PET

    • Author(s)
      Yamamoto Y, Tanaka K, Hoshikawa H, Toyohara J, Nishiyama Y
    • Organizer
      100th Scientific Assembly and Annual Meeting, Radiological Society of North America
    • Place of Presentation
      Chicago
    • Year and Date
      2014-11-30 – 2014-12-05
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] 4'-[Methyl-11C]thiothymidine PET for proliferation imaging in gastrointestinal cancer: comparison with 18F-FDG PET

    • Author(s)
      Yamamoto Y, Tanaka K, Toyohara J, NIshiyama Y
    • Organizer
      11th Congress of the World Federation of Nuclear Medicine and Biology
    • Place of Presentation
      Cancun
    • Year and Date
      2014-08-27 – 2014-08-31
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] Methionine-PET、4DST-PETを用いた悪性脳腫瘍診断・治療成績の検討

    • Author(s)
      稲次基希、成相直、林志保里、田中洋次、織田圭一、坂田宗之、豊原潤、石井賢二、石渡喜一、前原健寿
    • Organizer
      第37回日本脳神経CI学会,
    • Place of Presentation
      大宮ソニックシティー(埼玉県さいたま市)
    • Year and Date
      2014-02-28 – 2014-03-01
    • Data Source
      KAKENHI-PROJECT-23390344
  • [Presentation] 放射性薬剤入門ー構成から管理まで

    • Author(s)
      豊原潤
    • Organizer
      第54回日本核医学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2014-11-06 – 2014-11-08
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] Improved treatment of malignant glioma with clinical use of a newly developed PET molecular imaging probe 4DST to measure DNS synthesis rate. 2013 Annual Meeting of Congress of Neurosurgeons

    • Author(s)
      11.Nariai T, Inaji M, Hayashi S, Tanaka Y, Maehara T, Ishiwata K, Toyohara J
    • Organizer
      2013 Annual Meeting of Congress of Neurosurgeons.
    • Place of Presentation
      San Francisco,(USA)
    • Year and Date
      2013-10-19 – 2013-10-23
    • Data Source
      KAKENHI-PROJECT-23390344
  • [Presentation] 放射性フッ素18標識7alpha-alkyl-estradiol誘導体の構造活性相関

    • Author(s)
      豊原潤、岡本真由美、芝山啓允、中喬介、北川雄也、石渡喜一、清水功雄
    • Organizer
      日本薬学会第135回年会
    • Place of Presentation
      神戸
    • Year and Date
      2015-03-25 – 2015-03-28
    • Data Source
      KAKENHI-PROJECT-25293271
  • [Presentation] PET multi-tracerによるGlioma診断・治療の有用性

    • Author(s)
      17.稲次基希、成相直、田中洋次、林志保里、坂田宗之、織田圭一、石渡喜一、豊原潤、石井賢二、前原健寿
    • Organizer
      日本脳神経外科学会 第72回学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2013-10-16 – 2013-10-18
    • Data Source
      KAKENHI-PROJECT-23390344
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