Yamaguchi Kiyoshi 山口貴世志

… Alternative Names

YAMAGUCHI Kiyoshi 山口貴世志

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Researcher Number	50466843
Other IDs	https://orcid.org/0000-0003-2113-4369
Affiliation (Current)	2024: 東京大学, 医科学研究所, 准教授
Affiliation (based on the past Project Information) *help	2024: 東京大学, 医科学研究所, 准教授 2020 – 2022: 東京大学, 医科学研究所, 講師 2017 – 2019: 東京大学, 医科学研究所, 特任講師 2015: 東京大学, 医科学研究所, 特任講師 2011 – 2014: 東京大学, 医科学研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 50010:Tumor biology-related / Tumor therapeutics / Pathological medical chemistry / Drug development chemistry Except Principal Investigator Basic Section 49020:Human pathology-related / Basic Section 49030:Experimental pathology-related / Tumor biology / Medical genome science
Keywords	Principal Investigator 大腸がん / 遺伝子発現 / ゲノム / 分子標的治療 / 転写調節 / ブロモドメイン / エピジェネティクス / エピジェネティックリーダー / エピトランスクリプトーム / 遺伝子発現調節 … More / トランスクリプトーム / Wntシグナル / トランスクリプトーム解析 / Wntシグナル伝達 / 転写調節機構 / Wnt/β-cateninシグナル / 肝がん / 遺伝子発現制御 / 発現制御 / ヒストン修飾 / ゲノム創薬 … More Except Principal Investigator 肺癌 / NGS / 分子ネットワークモデル / 内在性レトロトランスポゾン / Toll Like Receptor / レトロトランスポゾン / 細胞増殖 / 自己免疫疾患 / 自己炎症性疾患 / トランスポゾン / TLR7 / Wnt / シグナル伝達 / がん / 大腸癌 / メチル基転移酵素 / ヒストン / 大腸がん / ゲノム / 疾患関連遺伝子 Less

Development of novel cancer therapy based on the characteristics of epigenetic leaders that are upregulated in tumorsPrincipal Investigator
- Principal Investigator
  
  山口貴世志
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  The University of Tokyo
Network analysis method for extracting useful molecules in HFLAC
- Principal Investigator
  
  笠島理加
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Kanagawa Cancer Center Research Institute
Understanding of Wnt-addicted cancer cells using comprehensives transcriptome dataPrincipal Investigator
- Principal Investigator
  
  Yamaguchi Kiyoshi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  The University of Tokyo
Elucidating the significance of amplified expression of endogenous retrotransposon in autoimmune/autoinflammatory diseases
- Principal Investigator
  
  Shibata Takuma
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  The University of Tokyo
Elucidation of mechanisms underlying colorectal tumorigenesis associated with deregulation of new Wnt targets
- Principal Investigator
  
  Furukawa Yoichi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  The University of Tokyo
Targeting novel bromodomain protein in colorectal cancerPrincipal Investigator
- Principal Investigator
  
  Yamaguchi Kiyoshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  The University of Tokyo
Functional analysis of a novel bromodomain protein in cancer cellsPrincipal Investigator
- Principal Investigator
  
  Yamaguchi Kiyoshi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  The University of Tokyo
Functional analysis of a histone methyltransferase in colorectal cancer by comprehensive genome analysis
- Principal Investigator
  
  FURUKAWA Yoichi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical genome science
- Research Institution
  The University of Tokyo
Development of novel cancer therapy through the targeting bromodomain proteinPrincipal Investigator
- Principal Investigator
  
  YAMAGUCHI Kiyoshi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  The University of Tokyo

[Book] 臨床病理レビューコンパニオン診断の進展2015
- Author(s)
  山口貴世志, 古川洋一
- Total Pages
  89
- Publisher
  克誠堂出版
- Data Source
  KAKENHI-PROJECT-26860206
[Journal Article] Identification of odontogenic ameloblast associated as a novel target gene of the Wnt/β-catenin signaling pathway.2023
- Author(s)
  Yamaguchi K, Horie C, Takane K, Ikenoue T, Nakagawa S, Isobe Y, Ota Y, Ushiku T, Tanaka M, Fujishiro J, Hoshino N, Arisue A, Nishizuka S, Aikou S, Shida D, Furukawa Y.
- Journal Title
  
  Cancer Sci.
  
  Volume: 114(3) Issue: 3 Pages: 948-960
- DOI
  10.1111/cas.15657
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06976, KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-20K07563, KAKENHI-PROJECT-21K07975, KAKENHI-PROJECT-20K17641
[Journal Article] Bromodomain protein BRD8 regulates cell cycle progression in colorectal cancer cells through a TIP60-independent regulation of the pre-RC complex2023
- Author(s)
  Yamaguchi Kiyoshi、Nakagawa Saya、Saku Akari、Isobe Yumiko、Yamaguchi Rui、Sheridan Paul、Takane Kiyoko、Ikenoue Tsuneo、Zhu Chi、Miura Masashi、Okawara Yuya、Nagatoishi Satoru、Kozuka-Hata Hiroko、Oyama Masaaki、Aikou Susumu、Ahiko Yuka、Shida Dai、Tsumoto Kouhei、Miyano Satoru、Imoto Seiya、Furukawa Yoichi
- Journal Title
  
  iScience
  
  Volume: 26 Issue: 4 Pages: 106563-106563
- DOI
  10.1016/j.isci.2023.106563
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21H05280, KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-20K07563
[Journal Article] Blocking PD-L1-PD-1 improves senescence surveillance and ageing phenotypes2022
- Author(s)
  Wang, T. W., Y. Johmura, N. Suzuki, S. Omori, T. Migita, K. Yamaguchi, S. Hatakeyama, S. Yamazaki, E. Shimizu, S. Imoto, Y. Furukawa, A. Yoshimura, and M. Nakanishi
- Journal Title
  
  Nature
  
  Volume: 611 Issue: 7935 Pages: 358-364
- DOI
  10.1038/s41586-022-05388-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19444, KAKENHI-PROJECT-21H05044, KAKENHI-PROJECT-19H03431, KAKENHI-PROJECT-20H03707, KAKENHI-PROJECT-20J21945, KAKENHI-PROJECT-21F21108, KAKENHI-PROJECT-20K07563, KAKENHI-ORGANIZER-19H05739
[Journal Article] The detectability and removal efficiency of SARS-CoV-2 in a large-scale septic tank of a COVID-19 quarantine facility in Japan2022
- Author(s)
  Iwamoto Ryo、Yamaguchi Kiyoshi、Arakawa Chisato、Ando Hiroki、Haramoto Eiji、Setsukinai Ken-ichi、Katayama Kotoe、Yamagishi Takuya、Sorano Sumire、Murakami Michio、Kyuwa Shigeru、Kobayashi Hiroyuki、Okabe Satoshi、Imoto Seiya、Kitajima Masaaki
- Journal Title
  
  Science of The Total Environment
  
  Volume: 849 Pages: 157869-157869
- DOI
  10.1016/j.scitotenv.2022.157869
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07563
[Journal Article] Motile sperm domain containing 1 is upregulated by the Wnt/β-catenin signaling pathway in colorectal cancer2022
- Author(s)
  Horie Chiaki、Zhu Chi、Yamaguchi Kiyoshi、Nakagawa Saya、Isobe Yumiko、Takane Kiyoko、Ikenoue Tsuneo、Ohta Yasunori、Tanaka Yukihisa、Aikou Susumu、Tsurita Giichiro、Ahiko Yuka、Shida Dai、Furukawa Yoichi
- Journal Title
  
  Oncology Letters
  
  Volume: 24 Issue: 2 Pages: 282-282
- DOI
  10.3892/ol.2022.13402
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07563, KAKENHI-PROJECT-21K07975, KAKENHI-PROJECT-20K17641
[Journal Article] Epigenetic traits inscribed in chromatin accessibility in aged hematopoietic stem cells2022
- Author(s)
  Itokawa Naoki、Oshima Motohiko、Koide Shuhei、Takayama Naoya、Kuribayashi Wakako、Nakajima-Takagi Yaeko、Aoyama Kazumasa、Yamazaki Satoshi、Yamaguchi Kiyoshi、Furukawa Yoichi、Eto Koji、Iwama Atsushi
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 2691-2691
- DOI
  10.1038/s41467-022-30440-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08366, KAKENHI-PROJECT-22K16298, KAKENHI-PROJECT-19H05653, KAKENHI-PROJECT-20H03707, KAKENHI-PROJECT-21F21108, KAKENHI-PROJECT-20K07563, KAKENHI-PLANNED-19H05746
[Journal Article] ERK-mediated NELF-A phosphorylation promotes transcription elongation of immediate-early genes by releasing promoter-proximal pausing of RNA polymerase II2022
- Author(s)
  Ohe Seina、Kubota Yuji、Yamaguchi Kiyoshi、Takagi Yusuke、Nashimoto Junichiro、Kozuka-Hata Hiroko、Oyama Masaaki、Furukawa Yoichi、Takekawa Mutsuhiro
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 7476-7476
- DOI
  10.1038/s41467-022-35230-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21H05280, KAKENHI-PROJECT-21H02692, KAKENHI-PROJECT-20K07563, KAKENHI-INTERNATIONAL-16K21739
[Journal Article] Senolysis by glutaminolysis inhibition ameliorates various age-associated disorders2021
- Author(s)
  Johmura Yoshikazu、Yamanaka Takehiro、Omori Satotaka、Wang Teh-Wei、Sugiura Yuki、Matsumoto Masaki、Suzuki Narumi、Kumamoto Soichiro、Yamaguchi Kiyoshi、Hatakeyama Seira、Takami Tomoyo、Yamaguchi Rui、Shimizu Eigo、Ikeda Kazutaka、Okahashi Nobuyuki、Mikawa Ryuta、Suematsu Makoto、Arita Makoto、Sugimoto Masataka et al
- Journal Title
  
  Science
  
  Volume: 371 Issue: 6526 Pages: 265-270
- DOI
  10.1126/science.abb5916
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07563, KAKENHI-PROJECT-20K21386, KAKENHI-PROJECT-20K21497, KAKENHI-PROJECT-18H05215, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-19H04969, KAKENHI-PUBLICLY-19H05243, KAKENHI-ORGANIZER-19H05739, KAKENHI-PLANNED-19H05740, KAKENHI-PUBLICLY-20H04940, KAKENHI-PROJECT-19H03431, KAKENHI-PROJECT-20J13207, KAKENHI-PROJECT-20J21945, KAKENHI-PROJECT-16H06276, KAKENHI-PLANNED-20H05930, KAKENHI-PROJECT-20H00495, KAKENHI-PROJECT-20H04116
[Journal Article] Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway2021
- Author(s)
  Fujino Takeshi、Goyama Susumu、Sugiura Yuki、Inoue Daichi、Asada Shuhei、Yamasaki Satoshi、Matsumoto Akiko、Yamaguchi Kiyoshi、Isobe Yumiko、Tsuchiya Akiho、Shikata Shiori、Sato Naru、Morinaga Hironobu、Fukuyama Tomofusa、Tanaka Yosuke、Fukushima Tsuyoshi、Takeda Reina、Yamamoto Keita、Honda Hiroaki et al
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 1826-1826
- DOI
  10.1038/s41467-021-22053-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07563, KAKENHI-PROJECT-19K22546, KAKENHI-PLANNED-19H05746, KAKENHI-PROJECT-19H03693, KAKENHI-PROJECT-19J01570, KAKENHI-PROJECT-19H03685
[Journal Article] Generation of a p16 Reporter Mouse and Its Use to Characterize and Target p16high Cells In Vivo.2020
- Author(s)
  Omori S, Wang TW, Johmura Y, ..., Sakamoto T (15番目), ..., Nakanishi M.
- Journal Title
  
  Cell Metab
  
  Volume: 32 Issue: 5 Pages: 814-828
- DOI
  10.1016/j.cmet.2020.09.006
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07659, KAKENHI-PROJECT-19K12215, KAKENHI-PROJECT-20K07563, KAKENHI-PROJECT-20K21497, KAKENHI-PROJECT-20K21612, KAKENHI-PROJECT-19KK0216, KAKENHI-PROJECT-17H06095, KAKENHI-PLANNED-17H06328, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06392, KAKENHI-ORGANIZER-19H05739, KAKENHI-PLANNED-19H05740, KAKENHI-PUBLICLY-20H04940, KAKENHI-PUBLICLY-20H05025, KAKENHI-PROJECT-20H00567, KAKENHI-PROJECT-19H03413, KAKENHI-PROJECT-19H03431, KAKENHI-PROJECT-20H03707, KAKENHI-PROJECT-19J01606, KAKENHI-PROJECT-20J21945, KAKENHI-PROJECT-17K07132, KAKENHI-PROJECT-18K15826, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18K06024, KAKENHI-PROJECT-20H03162, KAKENHI-PROJECT-20H03474
[Journal Article] Metagenome Data on Intestinal Phage-Bacteria Associations Aids the Development of Phage Therapy against Pathobionts2020
- Author(s)
  Fujimoto Kosuke、Kimura Yasumasa、Shimohigoshi Masaki、Satoh Takeshi、Sato Shintaro、Tremmel Georg、Uematsu Miho、Kawaguchi Yunosuke、Usui Yuki、Nakano Yoshiko、Hayashi Tetsuya、Kashima Koji、Yuki Yoshikazu、Yamaguchi Kiyoshi、Furukawa Yoichi、Kakuta Masanori、Akiyama Yutaka、Yamaguchi Rui、Crowe Sheila E. et al
- Journal Title
  
  Cell Host & Microbe
  
  Volume: 28 Issue: 3 Pages: 380-389
- DOI
  10.1016/j.chom.2020.06.005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07563, KAKENHI-PROJECT-19K17028, KAKENHI-PROJECT-19K17932, KAKENHI-PROJECT-18H02571, KAKENHI-PROJECT-19H03702, KAKENHI-PROJECT-19K22532, KAKENHI-PROJECT-18H05280
[Journal Article] Efficacy of the novel tubulin polymerization inhibitor PTC‐028 for myelodysplastic syndrome2020
- Author(s)
  Zhong Cheng、Kayamori Kensuke、Koide Shuhei、Shinoda Daisuke、Oshima Motohiko、Nakajima‐Takagi Yaeko、Nagai Yurie、Mimura Naoya、Sakaida Emiko、Yamazaki Satoshi、Iwano Satoshi、Miyawaki Atsushi、Ito Ryoji、Tohyama Kaoru、Yamaguchi Kiyoshi、Furukawa Yoichi、Lennox William、Sheedy Josephine、Weetall Marla、Iwama Atsushi
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 12 Pages: 4336-4347
- DOI
  10.1111/cas.14684
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06477, KAKENHI-PROJECT-20K07563, KAKENHI-PROJECT-20K21612, KAKENHI-PUBLICLY-20H05025, KAKENHI-PROJECT-19H05653, KAKENHI-PROJECT-20H03707
[Journal Article] Discovery of chemical probes that suppress Wnt/β-catenin signaling through high-throughput screening.2020
- Author(s)
  Yamaguchi K, Nagatoishi S, Tsumoto K, Furukawa Y.
- Journal Title
  
  Cancer Sci.
  
  Volume: 111 Issue: 3 Pages: 783-794
- DOI
  10.1111/cas.14297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-17K07214
[Journal Article] Response to the correspondence referring to our article “Development of an MSI-positive colon tumor with aberrant DNA methylation in a PPAP patient” by Pilar Mur, Claire Palles, Ian Tomlinson, Laura Valle2020
- Author(s)
  Yamaguchi Kiyoshi、Furukawa Yoichi
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 65 Issue: 6 Pages: 515-516
- DOI
  10.1038/s10038-020-0752-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07563
[Journal Article] EXOSC9 depletion attenuates P-body formation, stress resistance, and tumorigenicity of cancer cells.2020
- Author(s)
  Yoshino S, Matsui Y, Fukui Y, Seki M, Yamaguchi K, Kanamori A, Saitoh Y, Shimamura T, Suzuki Y, Furukawa Y, Kaneko S, Seiki M, Murakami Y, Inoue JI, Sakamoto T.
- Journal Title
  
  Sci Rep
  
  Volume: 10 Issue: 1 Pages: 9275-9275
- DOI
  10.1038/s41598-020-66455-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07659, KAKENHI-PROJECT-20K07563, KAKENHI-PROJECT-20K21832, KAKENHI-INTERNATIONAL-16K21739, KAKENHI-ORGANIZER-16H06573, KAKENHI-PLANNED-16H06575, KAKENHI-PUBLICLY-19H05210, KAKENHI-PUBLICLY-20H04841, KAKENHI-PROJECT-20H04281, KAKENHI-PROJECT-18H03207
[Journal Article] Development of an MSI-positive colon tumor with aberrant DNA methylation in a PPAP patient2019
- Author(s)
  Yamaguch K, Shimizu E, Yamaguchi R, Imoto S, Komura M, Hatakeyama S, Noguchi R, Takane K, Ikenoue T, Gohda Y, Yano H, Miyano S, Furukawa Y.
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03575
[Journal Article] Development of an MSI-positive colon tumor with aberrant DNA methylation in a PPAP patient2019
- Author(s)
  Yamaguchi K, Shimizu E, Yamaguchi R, Imoto S, Komura M, Hatakeyama S, Noguchi R, Takane K, Ikenoue T, Gohda Y, Yano H, Miyano S, Furukawa Y
- Journal Title
  
  J Hum Genet.
  
  Volume: 64(8) Issue: 8 Pages: 729-740
- DOI
  10.1038/s10038-019-0611-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-17H03575, KAKENHI-PROJECT-17K16530, KAKENHI-PROJECT-17K07214
[Journal Article] Importance of Gastric Cancer for the Diagnosis and Surveillance of Japanese Lynch Syndrome Patients2019
- Author(s)
  Ikenoue T, Arai M, Ishioka C, Iwama T, Kaneko S, Matsubara N, Moriya Y, Nomizu T, Sugano K, Tamura K, Tomita N, Yoshida T, Sugihara K, Naruse H, Yamaguchi K, Nojima M, Nakamura Y, Furukawa Y; Japanese society for cancer of the colon and rectum (JSCCR)
- Journal Title
  
  J Hum Genet.
  
  Volume: 64 Issue: 12 Pages: 1187-1194
- DOI
  10.1038/s10038-019-0674-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07763, KAKENHI-PROJECT-17H03575, KAKENHI-PROJECT-17K07214
[Journal Article] Anti-apoptotic effect by the suppression of IRF1 as a downstream of Wnt/β-catenin signaling in colorectal cancer cells2019
- Author(s)
  Ohsugi T, Yamaguchi K, Zhu C, Ikenoue T, Takane K, Shinozaki M, Tsurita G, Yano H, Furukawa Y.
- Journal Title
  
  Oncogene
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03575
[Journal Article] Anti-apoptotic effect by the suppression of IRF1 as a downstream of Wnt/β-catenin signaling in colorectal cancer cells2019
- Author(s)
  Ohsugi T, Yamaguchi K, Zhu C, Ikenoue T, Takane K, Shinozaki M, Tsurita G, Yano H, Furukawa Y
- Journal Title
  
  Oncogene
  
  Volume: 38(32) Issue: 32 Pages: 6051-6064
- DOI
  10.1038/s41388-019-0856-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03575, KAKENHI-PROJECT-17K09369, KAKENHI-PROJECT-17K16530, KAKENHI-PROJECT-17K07214
[Journal Article] Establishment and analysis of a novel mouse line carrying a conditional knockin allele of a cancer-specific FBXW7 mutation.2018
- Author(s)
  Ikenoue T, Terakado Y, Zhu C, Liu X, Ohsugi T, Matsubara D, Fujii T, Kakuta S,Kubo S, Shibata T, Yamaguchi K, Iwakura Y, Furukawa Y.
- Journal Title
  
  Sci Rep
  
  Volume: 8 Issue: 1 Pages: 2021-2021
- DOI
  10.1038/s41598-018-19769-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08672, KAKENHI-PROJECT-16K10558, KAKENHI-PROJECT-17K09369, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-26860227, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PUBLICLY-16H01569, KAKENHI-PROJECT-17K07214
[Journal Article] EGF Receptor and mTORC1 Are Novel Therapeutic Targets in Nonseminomatous Germ Cell Tumors2018
- Author(s)
  Chen Kenneth S.、Fustino Nicholas J.、Shukla Abhay A.、Stroup Emily K.、Budhipramono Albert、Ateek Christina、Stuart Sarai H.、Yamaguchi Kiyoshi、Kapur Payal、Frazier A. Lindsay、Lum Lawrence、Looijenga Leendert H.J.、Laetsch Theodore W.、Rakheja Dinesh、Amatruda James F.
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 17 Issue: 5 Pages: 1079-1089
- DOI
  10.1158/1535-7163.mct-17-0137
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07214
[Journal Article] Efficacy of liquid-based genetic diagnosis of endometrial cancer.2018
- Author(s)
  Matsuura M, Yamaguchi K, Tamate M, Satohisa S, Teramoto M, Iwasaki M, Sugita S, Hasegawa T, Koubo R, Takane K, Ikenoue T, Furukawa Y, Saito T.
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 12 Pages: 4025-4032
- DOI
  10.1111/cas.13819
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16530, KAKENHI-PROJECT-17H03575, KAKENHI-PROJECT-17K07214
[Journal Article] Fbxo22-mediated KDM4B degradation determines selective estrogen receptor modulator activity in breast cancer.2018
- Author(s)
  Johmura Y, Maeda I, Suzuki N, Wu W, Goda A,Morita M, Yamaguchi K, Yamamoto M, Nagasawa S, Kojima Y, Tsugawa K, Inoue N, Miyoshi Y, Osako T Akiyama F, Maruyama R, Inoue JI, Fukukawa Y, Ohta T, Nkanishi M.
- Journal Title
  
  J Clin Invest.
  
  Volume: 128 Issue: 12 Pages: 5603-5619
- DOI
  10.1172/jci121679
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08676, KAKENHI-PROJECT-18K15235, KAKENHI-PLANNED-16H06575, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05026, KAKENHI-PROJECT-17H03575, KAKENHI-PROJECT-17H03585, KAKENHI-PROJECT-16H06148, KAKENHI-PROJECT-16K15238, KAKENHI-PROJECT-17K18336, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-17H01398, KAKENHI-PROJECT-17K07214
[Journal Article] Regulation of tankyrase activity by a catalytic domain dimer interface2018
- Author(s)
  Fan Chen、Yarravarapu Nageswari、Chen Hua、Kulak Ozlem、Dasari Pranathi、Herbert Jeremiah、Yamaguchi Kiyoshi、Lum Lawrence、Zhang Xuewu
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 503 Issue: 3 Pages: 1780-1785
- DOI
  10.1016/j.bbrc.2018.07.113
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07214
[Journal Article] Genetic alterations in Japanese extrahepatic biliary tract cancer.2017
- Author(s)
  Noguchi R, Yamaguchi K, Ikenoue T, Terakado Y, Ohta Y, Yamashita N, Kainuma O, Yokoi S, Maru Y, Nagase H, Furukawa Y.
- Journal Title
  
  Oncology Letters
  
  Volume: 14 Issue: 1 Pages: 877-884
- DOI
  10.3892/ol.2017.6224
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09369, KAKENHI-PUBLICLY-16H01569, KAKENHI-PROJECT-17K07214
[Journal Article] Altered expression of microRNAs in patients with pouchitis after restorative proctocolectomy2017
- Author(s)
  Inoue Emi、Hata Keisuke、Kimura Hideaki、Yamaguchi Kiyoshi、Nojima Masanori、Endo Itaru、Shinozaki Masaru
- Journal Title
  
  Surgery Today
  
  Volume: 47 Issue: 12 Pages: 1484-1491
- DOI
  10.1007/s00595-017-1550-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07214
[Journal Article] Decreased expression of interferon-induced protein 2 (IFIT2) by Wnt/β-catenin signaling confers anti-apoptotic properties to colorectal cancer cells.2017
- Author(s)
  Ohsugi T, Yamaguchi K, Zhu C, Ikenoue T, Furukawa Y.
- Journal Title
  
  Oncotarget
  
  Volume: 8 Issue: 59 Pages: 100176-100186
- DOI
  10.18632/oncotarget.22122
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09369, KAKENHI-PROJECT-17H03575, KAKENHI-PUBLICLY-16H01569, KAKENHI-PROJECT-17K07214
[Journal Article] Bidirectional reporter assay using HAL promoter and TOPFLASH improves specificity in high-throughput screening of Wnt inhibitors.2017
- Author(s)
  Yamaguchi K, Zhu C, Ohsugi T, Yamaguchi Y, Ikenoue T, Furukawa Y.
- Journal Title
  
  Biotechnology and Bioengineering
  
  Volume: 114 Issue: 12 Pages: 2868-2882
- DOI
  10.1002/bit.26394
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09369, KAKENHI-PROJECT-17H03575, KAKENHI-PROJECT-17K07214
[Journal Article] Requirement of glycosylation machinery in TLR responses revealed by CRISPR/Cas9 screening2017
- Author(s)
  Sato Ryota、Shibata Takuma、Tanaka Yu、Kato Chiharu、Yamaguchi Kiyoshi、Furukawa Yoichi、Shimizu Eigo、Yamaguchi Rui、Imoto Seiya、Miyano Satoru、Miyake Kensuke
- Journal Title
  
  International Immunology
  
  Volume: 29 Issue: 8 Pages: 347-355
- DOI
  10.1093/intimm/dxx044
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19548, KAKENHI-PROJECT-16H06388, KAKENHI-PROJECT-17H03575, KAKENHI-PUBLICLY-16H01569, KAKENHI-PROJECT-16K08827, KAKENHI-PROJECT-17K07214
[Journal Article] FERM domain-containing protein 5 (FRMD5) as a novel target of β-catenin/TCF7L2 complex.2017
- Author(s)
  Zhu C, Yamaguchi K, Osugi T, Terakado Y, Noguchi R, Ikenoue T, Furukawa Y
- Journal Title
  
  Cancer Science
  
  Volume: 印刷中 Issue: 4 Pages: 612-619
- DOI
  10.1111/cas.13174
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01569, KAKENHI-PROJECT-17K09369, KAKENHI-PROJECT-17H03575, KAKENHI-PROJECT-17K07214
[Journal Article] Genetic alterations in Japanese extrahepatic biliary tract cancer.2016
- Author(s)
  Noguchi R, Yamaguchi K, Ikenoue T, Terakado Y, Ohta Y, Yamashita N, Kainuma O, Yokoi S, Maru Y, Nagase H, Furukawa Y
- Journal Title
  
  Oncol Lett
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860206
[Journal Article] A novel mouse model of intrahepatic cholangiocarcinoma induced by liver-specific Kras activation and Pten deletion.2016
- Author(s)
  Ikenoue T, Terakado Y, Nakagawa H, Hikiba Y, Fujii T, Matsubara D, Noguchi R, Zhu C, Yamamoto K, Kudo Y, Asaoka Y, Yamaguchi K, Ijichi H, Tateishi K, Fukushima N, Maeda S, Koike K, Furukawa Y
- Journal Title
  
  Sci Rep
  
  Volume: 印刷中 Issue: 1 Pages: 23899-23899
- DOI
  10.1038/srep23899
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860206, KAKENHI-PROJECT-25280105, KAKENHI-PROJECT-25290045, KAKENHI-PROJECT-25460432, KAKENHI-PROJECT-26460425, KAKENHI-PROJECT-26461031, KAKENHI-PROJECT-26462136, KAKENHI-PROJECT-16K15422, KAKENHI-PROJECT-16K08672, KAKENHI-PROJECT-16K10558, KAKENHI-PROJECT-26860227, KAKENHI-PROJECT-15H04806
[Journal Article] Detection of APC mosaicism by next-generation sequencing in an FAP patient.2015
- Author(s)
  Yamaguchi K, Komura M, Yamaguchi R, Imoto S, Shimizu E, Kasuya S, Shibuya T, Hatakeyama S, Takahashi N, Ikenoue T, Hata K, Tsurita G, Shinozaki M, Suzuki Y, Sugano S, Miyano S, Furukawa Y
- Journal Title
  
  J Hum Genet
  
  Volume: 60(5) Issue: 5 Pages: 227-231
- DOI
  10.1038/jhg.2015.14
- NAID
  40020462565
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26860206, KAKENHI-PROJECT-25280105
[Journal Article] Attenuated familial adenomatous polyposis with desmoids by an APC mutation2015
- Author(s)
  Ikenoue T, Yamaguchi K, Komura M, Imoto S, Yamaguchi R, Shimizu E, Kasuya S, Shibuya T, Hatakeyama S, Miyano S, Furukawa Y
- Journal Title
  
  Hum Genome Variation
  
  Volume: 2 Pages: 15011-15011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26860206
[Journal Article] Disruption of Wnt/β-catenin signaling and telomeric shortening are inextricable consequences of tankyrase inhibition in human cells.2015
- Author(s)
  Kulak O, Chen H, Holohan B, Wu X, He H, Borek D, Otwinowski Z, Yamaguchi K, Garofalo LA, Ma Z, Wright W, Chen C, Shay JW, Zhang X, Lum L
- Journal Title
  
  Mol Cell Biol
  
  Volume: 35(14) Issue: 14 Pages: 2425-2435
- DOI
  10.1128/mcb.00392-15
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860206
[Journal Article] A novel APC mosaicism in a patient with familial adenomatous polyposis.2015
- Author(s)
  Moriya Iwaizumi, Ken Sugimoto, et al.
- Journal Title
  
  Hum Genome Var
  
  Volume: 10 Issue: 1 Pages: 15057-15057
- DOI
  10.1038/hgv.2015.57
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460948, KAKENHI-PROJECT-25860530, KAKENHI-PROJECT-26860206, KAKENHI-PROJECT-25280105
[Journal Article] Identification of therapeutic small-molecule leads in cultured cells using multiplexed pathway reporter readouts. Chemical Biology--Methods and Protocols2015
- Author(s)
  Kulak O, Yamaguchi K, Lum L
- Journal Title
  
  Methods Mol Biol
  
  Volume: 1263 Pages: 3-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860206
[Journal Article] Molecular profiles of high-grade and low-grade pseudomyxoma peritonei.2015
- Author(s)
  Noguchi R, Yano H, Gohda Y, Suda R, Igari T, Ohta Y, Yamashita N, Yamaguchi K, Terakado Y, Ikenoue T, Furukawa Y
- Journal Title
  
  Cancer Med
  
  Volume: 4(12) Issue: 12 Pages: 1809-1816
- DOI
  10.1002/cam4.542
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26860206, KAKENHI-PROJECT-25280105
[Journal Article] Overexpression of cohesion establishment factor DSCC1 through E2F in colorectal cancer2014
- Author(s)
  Yamaguchi K, Yamaguchi R, Takahashi N, Ikenoue T, Fujii T, Shinozaki M, Tsurita G, Hata K, Niida A, Imoto S, Miyano S, Nakamura Y, Furukawa Y
- Journal Title
  
  PLoS ONE
  
  Volume: 9
- Data Source
  KAKENHI-PROJECT-23310137
[Journal Article] Identification of two Wnt-responsive elements in the intron of RING Finger Protein 43 (RNF43) gene.2014
- Author(s)
  Takahashi N, Yamaguchi K, Ikenoue T, Fujii T, Furukawa Y.
- Journal Title
  
  PLoS ONE
  
  Volume: 9 Issue: 1 Pages: e86582-e86582
- DOI
  10.1371/journal.pone.0086582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310137
[Journal Article] Identification of two Wnt-responsive elements in the intron of RING Finger Protein 43 (RNF43) gene2014
- Author(s)
  Takahashi N, Yamaguchi K, Ikenoue T, Fujii T, Furukawa Y
- Journal Title
  
  PLoS ONE
  
  Volume: 9
- Data Source
  KAKENHI-PROJECT-23310137
[Journal Article] Overexpression of cohesion establishment factor DSCC1 through E2F in colorectal cancer.2014
- Author(s)
  Yamaguchi K, Rui Yamaguchi R, Takahashi N, Ikenoue T, Fujii T, Shinozaki M, Tsurita G, Hata K, Niida A, Imoto S, Miyano S, Nakamura Y, Furukawa Y
- Journal Title
  
  PLoS ONE
  
  Volume: 9 Issue: 1 Pages: e85750-e85750
- DOI
  10.1371/journal.pone.0085750
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310137, KAKENHI-PROJECT-25280105
[Journal Article] Wnt3a stimulates maturation of impaired neutrophils developed from severe congenital neutropenia-derived pluipotent stem cells with heterozygous ELANE mutation.2013
- Author(s)
  Hiramoto T
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 110 Issue: 8 Pages: 3023-3028
- DOI
  10.1073/pnas.1217039110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591161, KAKENHI-PROJECT-23310137, KAKENHI-PROJECT-23650150, KAKENHI-PROJECT-23790126, KAKENHI-PROJECT-24390257, KAKENHI-PROJECT-24390272, KAKENHI-PROJECT-24659489, KAKENHI-PROJECT-25293231, KAKENHI-PLANNED-23106004
[Journal Article] Wnt3a stimulates maturation of impaired neutrophils developed from severe congenital neutropenia patient-derived pluripotent stem cells2013
- Author(s)
  Hiramoto T, Ebihara Y, Mizoguchi Y, Nakamura K, Yamaguchi K, Ueno K, Michizuki S, Yamamoto S, Nagasaki M, Furukawa Y, Tani K, Nakauchi H, Kobayashi M, Tsuji K
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 110(8) Pages: 3023-3028
- Data Source
  KAKENHI-PROJECT-23310137
[Journal Article] Smyd3 is required for the development of cardiac and skeletal muscle in zebrafish2011
- Author(s)
  Fujii T, Tsunesumi S, Yamaguchi K, Watanabe S, Furukawa Y
- Journal Title
  
  PLoS One
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310137
[Journal Article] MRG-binding protein contributes to colorectal cancer development2011
- Author(s)
  Yamaguchi K, Sakai M, Kim J, Tsunesumi S, Fujii T, Ikenoue T, Yamada Y, Akiyama Y, Muto Y, Yamaguchi R, Miyano S, Nakamura Y, Furukawa Y
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Pages: 1486-1492
- NAID
  10030242078
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790126
[Journal Article] MRG-binding protein contributes to colorectal cancer development2011
- Author(s)
  Yamaguchi K, Sakai M, Kim J, Tsunesumi S, Fujii T, Ikenoue T, Yamada Y, Akiyama Y, Muto Y, Yamaguchi R, Miyano S, Nakamura Y, Furukawa Y
- Journal Title
  
  Cancer Sci
  
  Volume: 102(8) Pages: 1486-92
- NAID
  10030242078
- Data Source
  KAKENHI-PROJECT-23310137
[Journal Article] Smyd3 is required for the development of cardiac and skeletal muscle in zebrafish2011
- Author(s)
  Fujii T, Tsunesumi S, Yamaguchi　K, Watanabe S, Furukawa Y
- Journal Title
  
  PLoS One
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790126
[Journal Article] MRG-binding protein contributes to colorectal cancer development.2011
- Author(s)
  Yamaguchi K, Sakai M, Kim J, Tsunesumi S, Fujii T, Ikenoue T, Yamada Y, Akiyama Y, Muto Y, Yamaguchi R, Miyano S, Nakamura Y, Furukawa Y.
- Journal Title
  
  Cancer Sci.
  
  Volume: 102(8) Pages: 1486-1492
- NAID
  10030242078
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790126
[Journal Article] Smyd3 is required for the development of cardiac and skeletal muscle in zebrafish2011
- Author(s)
  Fujii T, Tsunesumi S, Yamaguchi K, Watanabe S, & Furukawa Y
- Journal Title
  
  PLoS One
  
  Volume: 6(8)
- Data Source
  KAKENHI-PROJECT-23310137
[Journal Article] MRG-binding protein contributes to colorectal cancer development2011
- Author(s)
  Yamaguchi K, Sakai M, Kim J, Tsunesumi S, Fujii T, Ikenoue T, Yamada Y, Akiyama Y, Muto Y, Yamaguchi R, Miyano S, Nakamura Y, Furukawa Y
- Journal Title
  
  Cancer Science
  
  Volume: 102 Pages: 1486-1492
- NAID
  10030242078
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310137
[Journal Article] Smyd3 is required for the development of cardiac and skeletal muscle in zebrafish.2011
- Author(s)
  Fujii T, Tsunesumi S, Yamaguchi K, Watanabe S, Furukawa Y.
- Journal Title
  
  PLoS One.
  
  Volume: 6(8) Issue: 8 Pages: e23491-e23491
- DOI
  10.1371/journal.pone.0023491
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790126
[Patent] 転写因子を調節する上流のシグナル伝達経路および転写因子の活性を制御する分子および物質のスクリーニング方法2015
- Inventor(s)
  古川　洋一, 山口　貴世志
- Industrial Property Rights Holder
  国立大学法人東京大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-027182
- Filing Date
  2015-02-16
- Data Source
  KAKENHI-PROJECT-26860206
[Presentation] WGS analysis of Erbb2-amplified cervical cancer with two simultaneous histologic types: Transdifferentiation hypothesis2023
- Author(s)
  生島弘彬、内野慶太、山口貴世志、井元清哉、香田弘知、水上拓郎、森川鉄平、古川洋一
- Organizer
  第20回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07563
[Presentation] ブロモドメインタンパク質BRD8を標的とした新たな大腸がん治療戦略2022
- Author(s)
  山口貴世志、中川沙弥、高根希世子、池上恒雄、山口類、井元清哉、宮野悟、古川洋一
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07563
[Presentation] AP-1ファミリー転写因子FOSはポリオウイルス受容体PVRL4を転写制御する2022
- Author(s)
  七宮知之、高根希世子、山口貴世志、池上恒雄、藤幸知子、米田美佐子、甲斐知恵子、古川洋一
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07563
[Presentation] AP-1ファミリー転写因子FOSはポリオウイルス受容体PVRL4を転写制御する2022
- Author(s)
  七宮知之、高根希世子、山口貴世志、池上恒雄、藤幸知子、米田美佐子、甲斐知恵子、古川洋一
- Organizer
  第45回日本分子生物学年会
- Data Source
  KAKENHI-PROJECT-20K07563
[Presentation] APC関連ポリポーシスの可能性も検討された多発胃底腺ポリープの1例2022
- Author(s)
  小野山温那、阿彦友佳、柵山尚紀、山口貴世志、井元清哉、大田泰徳、愛甲丞、古川洋一、志田大
- Organizer
  第33回日本消化器癌発生学会総会
- Data Source
  KAKENHI-PROJECT-20K07563
[Presentation] 全ゲノム/全エクソン解析と人工知能を用いた難治がんに対する精密医療2022
- Author(s)
  池上恒雄、山口貴世志、高根希世子、清水英悟、笠島理加、土方康基、片山琴絵、渋谷哲朗、山口類、井元清哉、宮野悟、古川洋一
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07563
[Presentation] 新規Wnt/β-cateninシグナル標的遺伝子MOSPD1の大腸がんにおける発現と転写調節領域の解析2022
- Author(s)
  中川沙弥、山口貴世志、大河原悠哉、高根希世子、池上恒雄、古川洋一
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07563
[Presentation] Mint3阻害はin vivoでトリプルネガティブ乳がんを化学療法感受性にする2022
- Author(s)
  坂本毅治、田中伯享、山口貴世志、松原大祐、古川洋一
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07563
[Presentation] 遺伝子ネットワーク解析による高悪性度胎児性肺腺癌のパスウェイ予測・検討2022
- Author(s)
  笠島理加、鈴木理樹、清水英悟、玉田嘉紀、新井田厚司、廣島幸彦、片山琴絵、山口類、山口貴世志、古川洋一、宮野悟、井元清哉、横瀬智之、宮城洋平
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07563
[Presentation] 東京オリンピック・パラリンピック選手村におけるCOVID-19下水疫学調査の実装2022
- Author(s)
  北島正章、村上道夫、門屋俊祐、安藤宏紀、山口貴世志、岩本遼、黒板智博、岡部聡、片山浩之、井元清哉
- Organizer
  第25回日本水環境学会シンポジウム
- Data Source
  KAKENHI-PROJECT-20K07563
[Presentation] 虫垂原発腹膜偽粘液腫の網羅的DNAメチル化解析2022
- Author(s)
  蔡庭偉、高根希世子、山口貴世志、池上恒雄、合田良政、清松知充、矢野秀朗、福世真樹、関元昭、金田篤志、古川洋一
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07563
[Presentation] COVID-19軽症者等宿泊療養施設の下水からのSARS-CoV-2の検出：施設単位の下水疫学調査の実証2021
- Author(s)
  北島正章、岩本遼、佐野大輔、原本英司、山口貴世志、空野すみれ、山岸拓也、村上道夫、小林博幸、井元清哉、岡部聡
- Organizer
  第55回日本水環境学会年会
- Data Source
  KAKENHI-PROJECT-20K07563
[Presentation] Evaluation of MinION, a nanopore-based DNA sequencing device, for the screening and determination of structural variants in patients with Lynch syndrome2021
- Author(s)
  山口貴世志
- Organizer
  文部科学省科学研究費助成事業新学術領域研究「学術研究支援基盤形成」コホート・生体試料支援プラットフォーム令和２年度若手支援研究成果発表会
- Data Source
  KAKENHI-PROJECT-20K07563
[Presentation] 進行卵巣癌における腹水細胞診の意義2021
- Author(s)
  松浦基樹、西村庸子、玉手雅人、磯山響子、寺田倫子、岩崎雅宏、磯部友見子、畠山晴良、高根希世子、山口貴世志、池上恒雄、古川洋一、齋藤豪
- Organizer
  第62回日本婦人科腫瘍学会学術講演会
- Data Source
  KAKENHI-PROJECT-20K07563
[Presentation] 肝芽腫細胞において発現が亢進している遺伝子odontogenic ameloblast associated (ODAM)の解析2020
- Author(s)
  堀江千晶、山口貴世志、高根希世子、池上恒雄、古川洋一
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07563
[Presentation] 新規Wnt標的遺伝子histidine ammonia-lyase (HAL)の転写調節メカニズムの解析2020
- Author(s)
  中川沙弥、山口貴世志、高根希世子、池上恒雄、古川洋一
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07563
[Presentation] 日本人のリンチ症候群の診断及びサーベイランスにおける胃癌の重要性2020
- Author(s)
  池上恒雄、山口貴世志、野島正寛、古川洋一
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07563
[Presentation] 新たなスクリーニングシステムを用いたWnt阻害剤の探索2020
- Author(s)
  山口貴世志、高根希世子、池上恒雄、古川洋一
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07563
[Presentation] 当院における標準治療不応進行がん患者を対象としたクリニカルシーケンスの検討2020
- Author(s)
  土方康基、横山和明、山口貴世志、池上恒雄、山口類、井元清哉、内丸薫、宮野悟、四柳宏、東條有伸、古川洋一
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07563
[Presentation] 消化管遺伝性腫瘍の最前線2020
- Author(s)
  古川洋一、山口貴世志、笠島理加、清水英悟、高根希世子、山口類、井元清哉、宮野悟、池上恒雄
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07563
[Presentation] 麻疹ウイルス受容体PVRL4はBACH1により転写調節される2020
- Author(s)
  高根希世子、山口貴世志、池上恒雄、藤幸知子、米田美佐子、甲斐知恵子、古川洋一
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07563
[Presentation] CRISPR/Cas9システムを用いたトリプルネガティブ乳癌におけるEMT/MET可塑性制御機構の解析2020
- Author(s)
  山本瑞生、山口貴世志、古川洋一、井上純一郎
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07563
[Presentation] Wnt/β-catenin signaling controls interferon regulatory factor 1 (IRF1) in colorectal cancer cells2019
- Author(s)
  Kiyoshi Yamaguchi、Tomoyuki Ohsugi、Kiyoko Takane、Tsuneo Ikenoue、Yoichi Furukawa
- Organizer
  11th AACR-JCA Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07214
[Presentation] 大腸癌においてWnt /β-カテニンシグナルはインターフェロン制御因子1（IRF1）を制御する2019
- Author(s)
  大杉友之、山口貴世志、池上恒雄、高根希世子、篠崎大、矢野秀朗、釣田義一郎、古川洋一
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K07214
[Presentation] 大腸癌においてWnt /β-カテニンシグナルはインターフェロン制御因子2019
- Author(s)
  大杉友之, 山口貴世志, 池上恒雄, 高根希世子, 篠崎大, 矢野秀朗, 釣田義一郎, 古川洋一
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H03575
[Presentation] The CRISPR/Cas9-mediated gene knockout screening to analyze EMT-MET plasticity in triple-negative breast cancer2019
- Author(s)
  Mizuki Yamamoto、Kiyoshi Yamaguchi、Yoichi Furukawa、Jun-ichiro Inoue
- Organizer
  Cell Symposia: Hallmarks of Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07214
[Presentation] Wntシグナル経路の新規標的遺伝子odontogenic ameloblast associated (ODAM)の同定2019
- Author(s)
  堀江千晶、山口貴世志、高根希世子、池上恒雄、古川洋一
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K07214
[Presentation] CRISPR/Cas9システムを用いたトリプルネガティブ乳癌におけるEMT/MET可塑性制御機構の解析2019
- Author(s)
  山本瑞生、山口貴世志、古川洋一、井上純一郎
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K07214
[Presentation] CRISPR/Cas9システムを用いたトリプルネガティブ乳癌におけるEMT/MET可塑性制御機構の解析2019
- Author(s)
  山本瑞生、山口貴世志、古川洋一、井上純一郎
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K07214
[Presentation] ロングリードシーケンスによるリンチ症候群患者のミスマッチ修復遺伝子の構造異常の解析2019
- Author(s)
  山口貴世志、笠島理加、清水英悟、高根希世子、池上恒雄、山口類、井元清哉、宮野悟、古川洋一
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K07214
[Presentation] 子宮体がんスクリーニングにおける子宮内膜液状化細胞診検体を用いた遺伝子解析の有用性2019
- Author(s)
  池上恒雄、松浦基樹、高根希世子、山口貴世志、齋藤豪、古川洋一
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K07214
[Presentation] Kras活性化とPten欠損に起因するマウス肝内胆管癌における細胞内シグナルの検討2019
- Author(s)
  劉洵、池上恒雄、寺門侑美、高根希世子、山口貴世志、古川洋一
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K07214
[Presentation] ロングリードシーケンスによるリンチ症候群患者のミスマッチ修復遺伝子の構造異常の解析2019
- Author(s)
  山口貴世志, 笠島理加, 清水英悟, 高根希世子, 池上恒雄, 山口類, 井元清哉, 宮野悟, 古川洋一
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H03575
[Presentation] 麻疹ウイルス受容体PVRL4はがん細胞においてBACH1により調節される2019
- Author(s)
  高根希世子、山口貴世志、池上恒雄、藤幸知子、米田美佐子、甲斐知惠子、古川洋一
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K07214
[Presentation] Wnt/β-catenin signaling controls interferon regulatory factor 1 (IRF1) in colorectal cancer cells.2019
- Author(s)
  Yamaguchi K, Ohsugi T, Takane K, Ikenoue T, Furukawa Y
- Organizer
  11th AACR-JCA Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03575
[Presentation] Whole-exome sequencing of high-grade fetal lung adenocarcinomas2019
- Author(s)
  Masaki Suzuki, Rika Kasajima, Tomoyuki Yokose, Rui Yamaguchi, Seiya Imoto, Yoichi Furukawa, Satoru Miyano3 Emi Yoshioka, Kota Washimi, Yoichiro Okubo, Kae Kawachi, Yohei Miyagi
- Organizer
  The 16th Korean-Japanese Conjoint Slide Conference of International Academy of Pathology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03575
[Presentation] The CRISPR/Cas9-mediated gene knockout screening to analyze EMT-MET plasticity in triple-negative breast cancer.2019
- Author(s)
  Mizuki Yamamoto, Kiyoshi Yamaguchi, Yoichi Furukawa, Jun-ichiro Inoue.
- Organizer
  Cell Symposia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03575
[Presentation] Kras活性化とPten不活化による状況依存的なマウス肝腫瘍の誘導2018
- Author(s)
  池上恒雄、寺門侑美、劉洵、高根希世子、山口貴世志、古川洋一
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K07214
[Presentation] 子宮内膜液状化細胞診検体による遺伝子解析研究2018
- Author(s)
  松浦基樹、玉手雅人、郷久晴朗、寺本瑞絵、幸保莉香、畠山晴良、山口貴世志、杉田真太朗、池上恒雄、岩雅宏、長谷川匡、古川洋一、齋藤豪
- Organizer
  第59回日本臨床細胞学会春季大会
- Data Source
  KAKENHI-PROJECT-17K07214
[Presentation] Molecular features of colorectal cancer in patient with polymerase proofreading-associated polyposis (PPAP)2018
- Author(s)
  Kiyoshi Yamaguchi、Eigo Shimizu、Seira Hatakeyama、Rei Noguchi、Tsuneo Ikenoue、Rui Yamaguchi、Seiya Imoto、Satoru Miyano、Yoichi Furukawa
- Organizer
  The Joint Symposium of the 13th International Symposium of the Institute Network for Biomedical Sciences and the 28th Hot Spring Harbor International Symposium 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07214
[Presentation] FAP家系に発症した二卵性双胎肝芽腫2018
- Author(s)
  西塚哲、有末篤弘、高根希世子、山口貴世志、朝倉賀子、平井大士、遠藤幹也、水野大、石田和之、菅井有、宮野悟、古川洋一
- Organizer
  第6回日本家族性大腸腺腫症研究会学術集会
- Data Source
  KAKENHI-PROJECT-17K07214
[Presentation] ポリメラーゼ校正関連ポリポーシス患者由来の大腸腫瘍の遺伝子およびエピゲノム解析2018
- Author(s)
  山口貴世志、清水英悟、池上恒雄、高根希世子、山口類、井元清哉、宮野悟、古川洋一
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K07214
[Presentation] Molecular features of colorectal cancer in patient with polymerase proofreading-associated polyposis (PPAP)2018
- Author(s)
  Yamaguchi K, Shimizu E, Hatakeyama S, Noguchi R, Ikenoue T, Yamaguchi R, Imoto S, Miyano S, Furukawa Y
- Organizer
  The Joint Symposium of the 13th International Symposium of the Institute Network for Biomedical Sciences and the 28th Hot Spring Harbor International Symposium 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03575
[Presentation] 新規FBXW7癌特異的変異条件的ノックインマウスの樹立と解析2018
- Author(s)
  劉洵、池上恒雄、寺門侑美、朱赤、大杉友之、松原大祐、藤井智明、角田茂、久保幸子、柴田琢磨、山口貴世志、岩倉洋一郎、古川洋一
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K07214
[Presentation] Wntシグナルを抑制する物質探索のための新たなスクリーニング戦略2018
- Author(s)
  山口貴世志、古川洋一
- Organizer
  第9回スクリーニング学研究会
- Data Source
  KAKENHI-PROJECT-17K07214
[Presentation] Development of high-specific and sensitive reporter assays for the detection of Wnt/β-catenin signaling activity2018
- Author(s)
  Kiyoshi Yamaguchi、Chi Zhu、Tomoyuki Ohsugi、Akari Saku、Tsuneo Ikenoue、Yoichi Furukawa
- Organizer
  American Association for Cancer Research 109th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07214
[Presentation] Accurate and Robust Base-calling for Nanopore Raw Reads with Variation of Species Exploiting Neural Machine Translation Model2018
- Author(s)
  Hiroki Konishi、Rui Yamaguchi、Kiyoshi Yamaguchi、Yoichi Furukawa、Seiya Imoto
- Organizer
  The Joint Symposium of the 13th International Symposium of the Institute Network for Biomedical Sciences and the 28th Hot Spring Harbor International Symposium 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07214
[Presentation] 全ゲノム解析により同定されたポリメラーゼ校正関連ポリポーシスの発症に関わる新たなPOLE遺伝子変異2018
- Author(s)
  山口貴世志、清水英悟、上村光弘、山口類、井元清哉、池上恒雄、宮野悟、古川洋一
- Organizer
  日本人類遺伝学会第63回大会
- Data Source
  KAKENHI-PROJECT-17K07214
[Presentation] Kras変異とPten欠損に起因する肝内胆管癌発生進展におけるHes1の役割2017
- Author(s)
  池上恒雄、寺門侑美、松原大祐、山口貴世志、古川洋一
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K07214
[Presentation] Identification of FERM Domain-Containing Protein 5 (FRMD5) as a Novel Target of β-Catenin/TCF7L2 Complex2017
- Author(s)
  Furukawa Y, Zhu C, Ohsugi T, Terakado Y, Noguchi R, Ikenoue T, Yamaguchi K
- Organizer
  AACR Annual Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03575
[Presentation] Wnt阻害剤開発のための新たな化合物ライブラリスクリーニング戦略2017
- Author(s)
  山口貴世志、古川洋一
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K07214
[Presentation] Wntシグナル経路は大腸がんにおいてインターフェロン誘導タンパク質を抑制する2017
- Author(s)
  大杉友之、山口貴世志、朱赤、池上恒雄、古川洋一
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K07214
[Presentation] 腫瘍溶解性麻疹ウイルスレセプターPVRL4の発現調節機構の解明2017
- Author(s)
  朔あかり、山口貴世志、池上恒雄、藤幸知子、米田美佐子、秦裕子、尾山大明、甲斐知惠子、古川洋一
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K07214
[Presentation] 病態メカニズム解明のための腹膜偽粘液腫の遺伝子発現解析2017
- Author(s)
  野口玲、合田良政、秀野泰隆、山口貴世志、池上恒雄、猪狩亨、大田泰徳、矢野秀朗、古川洋一
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K07214
[Presentation] Wntシグナルで制御される分子FRMD5の大腸がんでの発現と役割2017
- Author(s)
  朱赤、大杉友之、寺門侑美、野口玲、池上恒雄、山口貴世志、古川洋一
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K07214
[Presentation] Wnt Signaling Induces Anti-Apoptotic Effect in Colorectal Cancer Cells Through the Suppression of IFIT2017
- Author(s)
  Ohsugi T, Zhu C, Ohsugi T, Terakado Y, Noguchi R, Ikenoue T, Yamaguchi K, Furukawa Y
- Organizer
  AACR Annual Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03575
[Presentation] Wnt signaling induces anti-apoptotic effect in colorectal cancer cells through the suppression of IFITs2017
- Author(s)
  Tomoyuki Ohsugi、Kiyoshi Yamaguchi、Chi Zhu、Tsuneo Ikenoue、Yoichi Furukawa
- Organizer
  American Association for Cancer Research 108th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07214
[Presentation] Identification of FERM domain-containing protein 5 (FRMD5) as a novel target of β-catenin/TCF7L2 complex2017
- Author(s)
  Yoichi Furukawa、Chi Zhu、Tomoyuki Ohsugi、Yumi Terakado、Rei Noguchi、Tsuneo Ikenoue、Kiyoshi Yamaguchi
- Organizer
  American Association for Cancer Research 108th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07214
[Presentation] 全ゲノム解析により見つかったFAP患者におけるAPC遺伝子の転写調節異常2017
- Author(s)
  山口貴世志、清水英悟、上村光弘、長山聡、山口類、井元清哉、池上恒雄、宮野悟、古川洋一
- Organizer
  第5回日本家族性大腸腺腫症研究会学術集会
- Data Source
  KAKENHI-PROJECT-17K07214
[Presentation] Next-generation sequencing as a potential tool in the diagnostics of APC mosaicism in FAP patient.2015
- Author(s)
  Kiyoshi Yamaguchi, Mitsuhiro Komura, Rui Yamaguchi, Seiya Imoto, Eigo Shimizu, Shinichi Kasuya, Tetsuo Shibuya, Seira Hatakeyama, Norihiko Takahashi, Tsuneo Ikenoue, Keisuke Hata, Giichiro Tsurita, Masaru Shinozaki, Yutaka Suzuki, Sumio Sugano, Satoru Miyano, Yoichi Furukawa
- Organizer
  American Association for Cancer Research 106th Annual Meeting
- Place of Presentation
  Philadelphia PA (USA)
- Year and Date
  2015-04-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860206
[Presentation] Efficacy of target enrichment-based sequencing for identifying genetic alterations in familial colorectal cancer.2015
- Author(s)
  山口貴世志, 陶弘, 倉地清隆, 前川真人, 岩泉守哉, 中村利夫, 井元清哉, 山口類, 上村光弘, 宮野悟, 椙村春彦, 古川洋一
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26860206
[Presentation] Next-generation sequencing detects a mosaic APC mutation present at low allele frequencies in an FAP patient.2015
- Author(s)
  Kiyoshi Yamaguchi, Mitsuhiro Komura, Rui Yamaguchi, Seiya Imoto, Eigo Shimizu, Shinichi Kasuya, Tetsuo Shibuya, Seira Hatakeyama, Norihiko Takahashi, Tsuneo Ikenoue, Keisuke Hata, Giichiro Tsurita, Masaru Shinozaki, Yutaka Suzuki, Sumio Sugano, Satoru Miyano, Yoichi Furukawa
- Organizer
  The Clinical Genome Conference
- Place of Presentation
  San Francisco CA (USA)
- Year and Date
  2015-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860206
[Presentation] 全ゲノム解析により同定された腺腫性大腸ポリポーシス患者のAPC遺伝子転写調節領域の欠失2015
- Author(s)
  山口貴世志, 上村光弘, 清水英悟, 長山聡, 山口類, 井元清哉, 渋谷哲朗, 池上恒雄, 宮野悟, 古川洋一
- Organizer
  日本人類遺伝学会第60回大会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2015-10-15
- Data Source
  KAKENHI-PROJECT-26860206
[Presentation] リングフィンガープロテイン43の転写調節機構および下流遺伝子解析2013
- Author(s)
  髙橋則彦　山口貴世志　池上恒雄　古川洋一
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23310137
[Presentation] DSCC1 is a novel biomarker for chemo-resistant colorectal cancer.2013
- Author(s)
  Kiyoshi Yamaguchi, Rui Yamaguchi, Masaru Shinozaki, Giichiro Tsurita, Keisuke Hata, Seiya Imoto, Satoru Miyano, Yusuke Nakamura, Yoichi Furukawa
- Organizer
  9th AACR-JCA Joint Conference
- Place of Presentation
  Maui HI, USA
- Data Source
  KAKENHI-PROJECT-23790126
[Presentation] DSCC1 is a novel biomarker for chemo-resistant colorectal cancer2013
- Author(s)
  Kiyoshi Yamaguchi, Rui Yamaguchi, Masaru Shinozaki, Giichiro Tsurita, Keisuke Hata, Seiya Imoto, Satoru Miyano, Yusuke Nakamura, Yoichi Furukawa.
- Organizer
  9th AACR-JCA Joint Conference
- Place of Presentation
  Hyatt Regency Maui (Maui HI, USA)
- Year and Date
  2013-02-21
- Data Source
  KAKENHI-PROJECT-23790126
[Presentation] Idenntification of a single nucleotide polymorphism associated with SIAH2 expression2013
- Author(s)
  Seham Elgazzar 髙橋則彦　山口貴世志　前仏均　片桐豊雅　池上恒雄　中村祐輔　古川洋一
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23310137
[Presentation] DSCC1 is a novel biomarker for chemo-resistant colorectal cancer.2013
- Author(s)
  Kiyoshi Yamaguchi, Rui Yamaguchi, Masaru Shinozaki, GIichiro Tsurita, Keisuke Hata, Seiya Imoto, Satoru Miyano, Yusuke Nakamura, Yoichi Furukawa
- Organizer
  The 9th AACR-JCA Joint Conference
- Place of Presentation
  Maui HI, USA
- Data Source
  KAKENHI-PROJECT-23310137
[Presentation] Identifying the target of histone methyltransferase SMYD3 in colorectal cancer cells.2012
- Author(s)
  山口貴世志, 池上恒雄, 宮野悟, 中村祐輔, 古川洋一
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌（札幌）
- Data Source
  KAKENHI-PROJECT-23790126
[Presentation] DSCC1 promotes survival of colorectal cancer cells through the induction of BCL2 expression.2012
- Author(s)
  Kiyoshi Yamaguchi, Rui Yamaguchi, Masaru Shinozaki, Giichiro Tsurita, Keisuke Hata, Seiya Imoto, Satoru Miyano, Yusuke Nakamura, Yoichi Furukawa
- Organizer
  8th International Symposium on Cancer Research and Therapy
- Place of Presentation
  東京会館（東京）
- Data Source
  KAKENHI-PROJECT-23790126
[Presentation] DSCC1 promotes survival of colorectal cancer cells through the induction of BCL2 expression2012
- Author(s)
  Kiyoshi Yamaguchi, Rui Yamaguchi, Masaru Shinozaki, Giichiro Tsurita, Keisuke Hata, Seiya Imoto, Satoru Miyano, Yusuke Nakamura, Yoichi Furukawa.
- Organizer
  8th International Symposium on Cancer Research and Therapy
- Place of Presentation
  東京会館(東京)
- Year and Date
  2012-11-09
- Data Source
  KAKENHI-PROJECT-23790126
[Presentation] Identifying the target of histone methyltransferase SMYD3 in colorectal cancer cells2012
- Author(s)
  山口貴世志、池上恒雄、宮野悟、中村祐輔、古川洋一
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌（札幌）
- Data Source
  KAKENHI-PROJECT-23310137
[Presentation] DSCC1 promotes survival of colorectal cancer cells through the inhibition of BCL2 expression2012
- Author(s)
  Kiyoshi Yamaguchi, Rui Yamaguchi, Masaru Shinozaki, GIichiro Tsurita, Keisuke Hata, Seiya Imoto, Satoru Miyano, Yusuke Nakamura, Yoichi Furukawa
- Organizer
  The 8th, International Symposium on Cancer Research and Therapy
- Place of Presentation
  東京会館（東京）
- Data Source
  KAKENHI-PROJECT-23310137
[Presentation] Identifying the target of histone methyltransferase SMYD3 in colorectal cancer cells2012
- Author(s)
  山口貴世志,池上恒雄,宮野悟,中村祐輔,古川洋一
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌(札幌)
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-23790126
[Presentation] Defective in sister chromatid cohesion 1 homolog (DSCC1), a novel target of E2F1 is overexpressed in colorectal cancer2011
- Author(s)
  山口貴世志,藤井智明,池上恒雄,中村祐輔,古川洋一
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(名古屋)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-23790126
[Presentation] MRGBP (C20orf20) contributes to development of colorectal cancer2011
- Author(s)
  Kiyoshi Yamaguchi, Michihiro Sakai, JooHun Kim, Yoshinao Yamada, Yoshiyuki Akiyama, Yusuke Nakamura, and Yoichi Furukawa.
- Organizer
  American Association for Cancer Research102th Annual Meeting
- Place of Presentation
  Orange County Convention Center (Orlando FL, USA)
- Year and Date
  2011-04-02
- Data Source
  KAKENHI-PROJECT-23790126
[Presentation] Defective in sister chromatoid cohesion 1 homolog (DSCC1), a novel target of E2F1 is overexpressed in colorectal cancer2011
- Author(s)
  山口貴世志、藤井智明、池上恒雄、中村祐輔、古川洋一
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-23310137
[Presentation] MRGBP (C20orf20) contributes to development of colorectal cancer2011
- Author(s)
  Kiyoshi Yamaguchi, Michihiro Sakai, Joohun Kim, Yoshinao Yamada, Yoshiyuki Akiyama, Yusuke Nakamura, Yoichi Furukawa
- Organizer
  The 102th. Annual meeting of American Association for Cancer Research
- Place of Presentation
  Orlando FL, USA
- Year and Date
  2011-04-04
- Data Source
  KAKENHI-PROJECT-23310137
[Presentation] Defective in sister chromatid cohesion 1 homolog (DSCC1), a novel target of E2F1 is overexpressed in colorectal cancer2011
- Author(s)
  山口貴世志, 藤井智明, 池上恒雄, 中村祐輔, 古川洋一
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23790126
[Presentation] Genetic analysis of cancer associated genes in Japanese biliary tract cancer using next generation sequencer
- Author(s)
  野口玲, 山口貴世志, 荒川茉莉子, 太田泰徳, 池上恒雄, 古川洋一
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26860206
[Presentation] Genetic analysis for hereditary tumors by exome sequencing
- Author(s)
  荒川茉莉子, 野口玲, 山口貴世志, 粕谷慎一, 山口類, 井元清哉, 宮野悟, 池上恒雄, 古川洋一
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26860206
[Presentation] A novel mouse model of intrahepatic cholangiocarcinoma induced by liver-specific Kras activation and Pten deletion
- Author(s)
  寺門侑美, 池上恒雄, 山口貴世志, 浅岡良成, 伊地知秀明, 立石敬介, 小池和彦, 古川洋一
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26860206
[Presentation] Search for pathogenic variants in familial colorectal cancer using a next generation sequencer
- Author(s)
  山口貴世志, 上村光弘, 清水英悟, 粕谷慎一, 山口類, 渋谷哲朗, 井元清哉, 長山聡, 高橋則彦, 池上恒雄, 菅野純夫, 鈴木穣, 宮野悟, 古川洋一
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26860206
[Presentation] The interferon-induced protein family is down-regulated through the canonical WNT-signaling pathway
- Author(s)
  大杉友之, 山口貴世志, 朱赤, 黄雨晴, 池上恒雄, 古川洋一
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26860206
[Presentation] Establishment of a novel mouse model of intrahepatic cholangiocarcinoma using liver-specific Kras activation and Pten deletion
- Author(s)
  Tsuneo Ikenoue, Yumi Terakado, Kiyoshi Yamaguchi, Yoichi Furukawa
- Organizer
  9th International Symposium on Cancer Research and Therapy
- Place of Presentation
  東京
- Year and Date
  2014-10-31 – 2014-11-01
- Data Source
  KAKENHI-PROJECT-26860206
[Presentation] Bromodomain Protein BRD8 is a novel therapeutic target for colorectal cancer
- Author(s)
  Kiyoshi Yamaguchi, Masashi Miura, Chi Zhu, Tsuneo Ikenoue, Satoru Nagatoishi, Kouhei Tsumoto, Yoichi Furukawa
- Organizer
  9th International Symposium on Cancer Research and Therapy
- Place of Presentation
  東京
- Year and Date
  2014-10-31 – 2014-11-01
- Data Source
  KAKENHI-PROJECT-26860206
[Presentation] Identification of genetic alterations in biliary tract cancer using multiplex PCR for cancer associated genes
- Author(s)
  Rei Noguchi, Kiyoshi Yamaguchi, Yasunori Ohta, Tsuneo Ikenoue, Yoichi Furukawa
- Organizer
  9th International Symposium on Cancer Research and Therapy
- Place of Presentation
  東京
- Year and Date
  2014-10-31 – 2014-11-01
- Data Source
  KAKENHI-PROJECT-26860206
[Presentation] リンチ症候群を強く疑わせる家族歴を持つ、同時多発大腸がんの症例
- Author(s)
  野口玲, 山口貴世志, 矢野秀朗, 合田良政, 須田竜一郎, 池上恒雄, 古川洋一
- Organizer
  第20回家族性腫瘍学会　学術集会
- Place of Presentation
  福島
- Year and Date
  2014-06-13 – 2014-06-14
- Data Source
  KAKENHI-PROJECT-26860206

1. FURUKAWA Yoichi (20272560)

# of Collaborated Projects: 4 results

# of Collaborated Products: 82 results
2. IKENOUE Tsuneo (80396712)

# of Collaborated Projects: 2 results

# of Collaborated Products: 22 results
3. YAMAGUCHI Rui (90380675)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
4. Shibata Takuma (30554505)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 竹本経緯子 (90243104)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 山口卓男 (80596601)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 小沢学 (80608787)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 笠島理加 (20630875)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 宮城洋平 (00254194)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 鈴木理樹 (00770108)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 井元清哉 (10345027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. SAKAMOTO Takeharu

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
13. MATSYBARA Daisuk

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. SUGIMOTO Ken

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. OYAMA Masaaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
16. ITO Ryoji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. WU Wenwen

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. NAGATOISHI Satoru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. OHSHIMA Motohiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 吉村昭彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 田中麻理子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 秦裕子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
23. 高根希世子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 三宅健介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 宮野悟

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 富田尚裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 田村和朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamaguchi Kiyoshi 山口 貴世志

YAMAGUCHI Kiyoshi 山口 貴世志

Research Projects

Research Products

Co-Researchers

Development of novel cancer therapy based on the characteristics of epigenetic leaders that are upregulated in tumorsPrincipal Investigator

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Network analysis method for extracting useful molecules in HFLAC

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Understanding of Wnt-addicted cancer cells using comprehensives transcriptome dataPrincipal Investigator

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Elucidating the significance of amplified expression of endogenous retrotransposon in autoimmune/autoinflammatory diseases

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Elucidation of mechanisms underlying colorectal tumorigenesis associated with deregulation of new Wnt targets

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Targeting novel bromodomain protein in colorectal cancerPrincipal Investigator

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Functional analysis of a novel bromodomain protein in cancer cellsPrincipal Investigator

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Functional analysis of a histone methyltransferase in colorectal cancer by comprehensive genome analysis

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Development of novel cancer therapy through the targeting bromodomain proteinPrincipal Investigator

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[Book] 臨床病理レビュー コンパニオン診断の進展2015

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[Journal Article] Identification of odontogenic ameloblast associated as a novel target gene of the Wnt/β-catenin signaling pathway.2023

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[Journal Article] Bromodomain protein BRD8 regulates cell cycle progression in colorectal cancer cells through a TIP60-independent regulation of the pre-RC complex2023

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[Journal Article] Blocking PD-L1-PD-1 improves senescence surveillance and ageing phenotypes2022

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[Journal Article] The detectability and removal efficiency of SARS-CoV-2 in a large-scale septic tank of a COVID-19 quarantine facility in Japan2022

Yamaguchi Kiyoshi 山口貴世志

YAMAGUCHI Kiyoshi 山口貴世志

[Book] 臨床病理レビューコンパニオン診断の進展2015