Takubo Keiyo 田久保圭誉

… Alternative Names

TAKUBO Keiyo 田久保圭誉

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Researcher Number	50502788
Other IDs	https://orcid.org/0000-0002-1736-7592
Affiliation (Current)	2025: 東北大学, 医学系研究科, 教授 2025: 国立研究開発法人国立国際医療研究センター, 研究所, 生体恒常性プロジェクト長 2025: 国立研究開発法人国立国際医療研究センター, その他部局等, 生体恒常性プロジェクト長
Affiliation (based on the past Project Information) *help	2025: 東北大学, 医学系研究科, 教授 2021 – 2024: 国立研究開発法人国立国際医療研究センター, 研究所, 生体恒常性プロジェクト長 2015 – 2020: 国立研究開発法人国立国際医療研究センター, その他部局等, 生体恒常性プロジェクト長 2018: 慶應義塾大学, 医学部, 講師 2018: 国立研究開発法人国立国際医療研究センター, 研究所生体恒常性プロジェクト, プロジェクト長 … More 2016: 国立研究開発法人国立国際医療研究センター, その他部局, 生体恒常性プロジェクト長 2015 – 2016: 国立研究開発法人国立国際医療研究センター, 生体恒常性プロジェクト長 2014: 国立国際医療研究センター研究所, プロジェクト長 2014: 独立行政法人国立国際医療研究センター, その他部局等, その他 2013 – 2014: 慶應義塾大学, 医学部, 専任講師 2011 – 2014: 慶應義塾大学, 医学部, 講師 2008 – 2010: 慶應義塾大学, 医学部, 助教 Less
Review Section/Research Field	Principal Investigator Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Hematology / Biological Sciences / Basic Section 54010:Hematology and medical oncology-related / Transformative Research Areas, Section (III) / Biological Sciences Except Principal Investigator Hematology / Biological Sciences / Medium-sized Section 49:Pathology, infection/immunology, and related fields / Integrative animal science / Biological Sciences
Keywords	Principal Investigator 造血幹細胞 / 幹細胞ニッチ / 骨髄 / in vivoイメージング / 低酸素 / メタボロミクス / イメージング / ニッチ / 巨核球 / 細胞動態 … More / 画像解析 / 幹細胞代謝 / 血小板 / 低酸素応答 / 老化 / 代謝リプログラミング / リアルタイムATP濃度解析 / 定量生物学 / 単一細胞解析 / 解糖系 / 微小循環 / 幹細胞性 / 造血前駆細胞 / 幹細胞増幅 / ニッチ細胞 / 感染応答 / SASP / ストレス応答 / 単一細胞トランスクリプトーム解析 / メタボローム解析 / メタボローム / 白血病幹細胞 / 微小環境 / 酸素代謝 / GO期 / VHL / HIF-1 / 静止期 / 未分化型精原細胞 / 幹細胞純化 / 精子幹細胞 … More Except Principal Investigator ニッチ / 活性酸素 / 造血幹細胞 / 幹細胞 / 低酸素 / エイジング / 疾患 / 老化 / ステムセルエイジング / 白血病幹細胞 / 細胞周期 / 自己複製能 / 経口免疫寛容 / 絶食応答 / 骨髄 / パイエル板 / 腸ー骨髄連関 / 経口寛容 / 栄養シグナル / 腸管免疫 / 生体機能利用 / 細胞・組織 / 発生・分化 / 移植・再生医療 / 間葉系細胞 / 血液学 / 免疫学 / 再生医学 / 応用動物 / 骨髄増殖性疾患 / 造血ニッチ / 髄外造血 / 脾腫 / 脾臓 / 再生 / 発生 / 転写因子 / 微小環境 / 造血 / 炎症性サイトカイン / 巨核球 / 幹細胞制御 / 人工ニッチ / 幹細胞老化 / 幹細胞ニッチ / 細胞回転 / 細胞代謝 / 幹細胞老化と疾患 / 総括班 / 加齢 / ニッチ因子 / プロスタグランディン / 炎症 / PO / Fbw / 多発性骨髄腫 / IL-2Rα / VE-カドヘリン / CML / 血液腫瘍疾患 / 癌幹細胞 / TIE2受容体 / thrombopoietin / mpl / TIE2 / Angiopoiedn-1 / ATM / Thrombopoietin / Mpl / Angiopoietin-1 / Tie2 / 骨芽細胞 Less

動的な酸素シグナルによる非典型的細胞運命決定機構の解明Principal Investigator
- Principal Investigator
  
  田久保圭誉
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Tohoku University
侵害受容神経による造血幹細胞の骨髄間移動制御の解明と応用Principal Investigator
- Principal Investigator
  
  田久保圭誉
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  National Center for Global Health and Medicine
Establishment of real-time measurement technique for ATP concentration and amount in single hematopoietic stem cellsPrincipal Investigator
- Principal Investigator
  
  Takubo Keiyo
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  National Center for Global Health and Medicine
Establishment of imaging technique for spatiotemporal dynamics of hematopoietic stem cells in bone marrowPrincipal Investigator
- Principal Investigator
  
  Takubo Keiyo
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  National Center for Global Health and Medicine
Spatio-temporal analysis of hematopoietic stem cell dynamics through visualization and manipulation of bone marrow oxygen environmentPrincipal Investigator
- Principal Investigator
  
  Takubo Keiyo
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  National Center for Global Health and Medicine
Starvation response of the immune system along the gut-bone marrow axis
- Principal Investigator
  
  Hase Koji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Keio University
Measuring shape and movement of hematopoietic stem cellsPrincipal Investigator
- Principal Investigator
  
  Takubo Keiyo
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  National Center for Global Health and Medicine
Composition and function of metabolites as hematopoietic stem cell niche factorsPrincipal Investigator
- Principal Investigator
  
  Takubo Keiyo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  National Center for Global Health and Medicine
Identification and characterization of biological targets of chemical expander for hematopoietic stem cellsPrincipal Investigator
- Principal Investigator
  
  Takubo Keiyo
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  National Center for Global Health and Medicine
Research on spleen microenvironment supporting extramedullary hematopoiesis and its application to the expansion of hematopoietic stem cells
- Principal Investigator
  
  GOITSUKA RYO
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Integrative animal science
- Research Institution
  Tokyo University of Science
Establishing a new paradigm of pathogenesis of the diseases through the understanding of stem cell aging
- Principal Investigator
  
  Iwama Atsushi
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
  Chiba University
Impact of hydroxylation signals on homeostatic regulation of hematopoiesisPrincipal Investigator
- Principal Investigator
  
  Takubo Keiyo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  National Center for Global Health and Medicine
Establishing a new paradigm of pathogenesis of the diseases through the understanding of stem cell aging
- Principal Investigator
  
  Iwama Atsushi
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
  Chiba University
Aging and anti-aging mechanisms in niche-hematopoietic stem cell interactionPrincipal Investigator
- Principal Investigator
  
  TAKUBO Keiyo
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  National Center for Global Health and Medicine
Homeostasis of hematopoietic stem cells and its breakdown
- Principal Investigator
  
  SUDA Toshio
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Hematology
- Research Institution
  Kumamoto University
造血幹細胞ニッチとしての巨核球の機能の解明Principal Investigator
- Principal Investigator
  
  田久保圭誉
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
低酸素適応システムによる巨核球への分化・成熟過程の解析Principal Investigator
- Principal Investigator
  
  田久保圭誉
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
Nicher Regulation for Normal Hemopoietic Stem Cells and Leukemic Stem Cells
- Principal Investigator
  
  SUDA Toshio
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  Keio University
Elucidation of metabolic phenotypes of LICs and development of targeting therapy against LICs through Phd/VHL/HIF-1 regulatory systemPrincipal Investigator
- Principal Investigator
  
  TAKUBO Keiyo
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Hematology
- Research Institution
  Keio University
Analysis of Niche Regulation for Cancer Stem Cells
- Principal Investigator
  
  TOSHIO Suda
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
ニッチによる幹細胞の運命制御
- Principal Investigator
  
  須田年生
- Project Period (FY)
  2010
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Hematology
- Research Institution
  Keio University
未分化型精原細胞特異的遺伝子ネットワークによる幹細胞維持機構の解明Principal Investigator
- Principal Investigator
  
  田久保圭誉
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
Molecular mechanisms for hematopoietic stem cells by HIF-1/VHL regulatory systemPrincipal Investigator
- Principal Investigator
  
  TAKUBO Keiyo
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Keio University
Regulation of Hematopoietic Stem Cell Division in a Niche
- Principal Investigator
  
  SUDA Toshio
- Project Period (FY)
  2004 – 2008
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University

[Book] Advances in Hematopoietic Stem Cell Research(Edited by Rosana Pelayo)2012
- Author(s)
  Keiyo Takubo
- Total Pages
  464
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-23689049
[Book] Advances in Hematopoietic Stem Cell Research(Edited by Rosana Pelayo)2012
- Author(s)
  Keiyo Takubo
- Total Pages
  464
- Publisher
  InTech
- Data Source
  KAKENHI-PUBLICLY-23118527
[Journal Article] Context-dependent modification of PFKFB3 in hematopoietic stem cells promotes anaerobic glycolysis and ensures stress hematopoiesis2024
- Author(s)
  Watanuki S et al
- Journal Title
  
  eLife
  
  Volume: 12
- DOI
  10.7554/elife.87674
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18137, KAKENHI-PROJECT-23K06416, KAKENHI-PROJECT-21K06072, KAKENHI-PROJECT-21K08431, KAKENHI-PROJECT-22K19550, KAKENHI-PROJECT-22K16298, KAKENHI-PROJECT-21H02957, KAKENHI-PROJECT-23K23797
[Journal Article] Imeglimin improves systemic metabolism by targeting brown adipose tissue and gut microbiota in obese model mice.2024
- Author(s)
  Awazawa M, Matsushita M, Nomura I, Kobayashi N, Tamura-Nakano M, Sorimachi Y, Takubo K, Ueki K.
- Journal Title
  
  Metabolism
  
  Volume: 153 Pages: 155796-155796
- DOI
  10.1016/j.metabol.2024.155796
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19550, KAKENHI-PROJECT-22KJ2948, KAKENHI-PROJECT-21H02957
[Journal Article] Abcb10 regulates murine hematopoietic stem cell potential and erythroid differentiation2024
- Author(s)
  Yahagi Ayano、Mochizuki-Kashio Makiko、Sorimachi Yuriko、Takubo Keiyo、Nakamura-Ishizu Ayako
- Journal Title
  
  Experimental Hematology
  
  Volume: - Pages: 104191-104191
- DOI
  10.1016/j.exphem.2024.104191
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22KK0266, KAKENHI-PROJECT-21K08425, KAKENHI-PROJECT-22K19550, KAKENHI-PROJECT-21H02957
[Journal Article] Mesenchymal loss of p53 alters stem cell capacity and models human soft tissue sarcoma traits.2023
- Author(s)
  Sorimachi Y, Kobayashi H, Shiozawa Y, Koide S, Nakato R, Shimizu Y, Okamura T, Shirahige K, Iwama A, Goda N, Takubo K, Takubo K.
- Journal Title
  
  Stem Cell Reports
  
  Volume: S2213-6711(23) Issue: 5 Pages: 00097-8
- DOI
  10.1016/j.stemcr.2023.03.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-20H05940, KAKENHI-PROJECT-23K06416, KAKENHI-PROJECT-21K08431, KAKENHI-PROJECT-22K19550, KAKENHI-PROJECT-22K16298, KAKENHI-PROJECT-22KJ2948, KAKENHI-PLANNED-19H05746, KAKENHI-PROJECT-19H05653, KAKENHI-PROJECT-20H05686, KAKENHI-PROJECT-21H02957
[Journal Article] Potential Involvement of Oxidative Stress in Ligamentum Flavum Hypertrophy2023
- Author(s)
  Ito K, Kise H, Suzuki S, Nagai S, Hachiya K, Takeda H, Kawabata S, Ikeda D, Takubo K, Kaneko S, Fujita N.
- Journal Title
  
  J Clin Med
  
  Volume: 12 Issue: 3 Pages: 808-808
- DOI
  10.3390/jcm12030808
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19550, KAKENHI-PROJECT-21H02957, KAKENHI-PROJECT-23K08661, KAKENHI-PROJECT-20K18041
[Journal Article] Distinct roles of the preparatory and payoff phases of glycolysis in hematopoietic stem cells2023
- Author(s)
  Shiroshita Kohei、Kobayashi Hiroshi、Takubo Keiyo
- Journal Title
  
  Experimental Hematology
  
  Volume: 124 Pages: 56-67
- DOI
  10.1016/j.exphem.2023.06.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08431, KAKENHI-PROJECT-22K19550, KAKENHI-PROJECT-22KJ2948, KAKENHI-PROJECT-21H02957
[Journal Article] Evaluating the function of murine quiescent hematopoietic stem cells following non-homologous end joining-based genome editing2023
- Author(s)
  Shiroshita Kohei、Kobayashi Hiroshi、Takubo Keiyo
- Journal Title
  
  STAR Protocols
  
  Volume: 4 Issue: 2 Pages: 102347-102347
- DOI
  10.1016/j.xpro.2023.102347
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08431, KAKENHI-PROJECT-22K19550, KAKENHI-PROJECT-21H02957
[Journal Article] Spatial heterogeneity of bone marrow endothelial cells unveils a distinct subtype in the epiphysis2023
- Author(s)
  Iga Takahito、Kobayashi Hiroshi、Kusumoto Dai、Sanosaka Tsukasa、Fujita Nobuyuki、Tai-Nagara Ikue、Ando Tomofumi、Takahashi Tomoko et.al
- Journal Title
  
  Nature Cell Biology
  
  Volume: 25 Issue: 10 Pages: 1415-1425
- DOI
  10.1038/s41556-023-01240-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23KJ1885, KAKENHI-PROJECT-22K06915, KAKENHI-PROJECT-21K08431, KAKENHI-PROJECT-22K19550, KAKENHI-PROJECT-19H03623, KAKENHI-PROJECT-21H02957, KAKENHI-PROJECT-21H03057, KAKENHI-PROJECT-23K21467, KAKENHI-PROJECT-23K27352
[Journal Article] MBTD1 preserves adult hematopoietic stem cell pool size and function2023
- Author(s)
  Takubo Keiyo、Htun Phyo Wai、Ueda Takeshi、Sera Yasuyuki、Iwasaki Masayuki、Koizumi Miho、Shiroshita Kohei、Kobayashi Hiroshi、Haraguchi Miho、Watanuki Shintaro、Honda Zen-ichiro、Yamasaki Norimasa、Nakamura-Ishizu Ayako、Arai Fumio、Motoyama Noboru、Hatta Tomohisa、Natsume Tohru、Suda Toshio、Honda Hiroaki
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 120 Issue: 32
- DOI
  10.1073/pnas.2206860120
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16333, KAKENHI-PROJECT-21K08378, KAKENHI-PROJECT-23K07134, KAKENHI-PROJECT-21K08431, KAKENHI-PROJECT-22K19550, KAKENHI-PROJECT-21H02957, KAKENHI-PROJECT-23K27442
[Journal Article] Mitf is required for T cell maturation by regulating dendritic cell homing to the thymus2022
- Author(s)
  Karigane D, Haraguchi M, Toyama-Sorimachi N, Nishimura EK,?Takubo K.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 5966 Pages: 29035-29035
- DOI
  10.1016/j.bbrc.2022.01.091
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21621, KAKENHI-PROJECT-21H02957
[Journal Article] Quantitative Analysis of Sympathetic and Nociceptive Innervation Across Bone Marrow Regions in Mice2022
- Author(s)
  Fujita Shinya、Morikawa Takayuki、Tamaki Shinpei、Sezaki Maiko、Takizawa Hitoshi、Okamoto Shinichiro、Kataoka Keisuke、Takubo Keiyo
- Journal Title
  
  Experimental Hematology
  
  Volume: 112-113 Pages: 44-59
- DOI
  10.1016/j.exphem.2022.07.297
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08383, KAKENHI-PROJECT-22K19550, KAKENHI-PROJECT-21H02957
[Journal Article] Approaches towards Elucidating the Metabolic Program of Hematopoietic Stem/Progenitor Cells2022
- Author(s)
  Kobayashi Hiroshi、Watanuki Shintaro、Takubo Keiyo
- Journal Title
  
  Cells
  
  Volume: 11 Issue: 20 Pages: 3189-3189
- DOI
  10.3390/cells11203189
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08431, KAKENHI-PROJECT-22K19550, KAKENHI-PROJECT-21H02957
[Journal Article] RNaseH2A downregulation drives inflammatory gene expression via genomic DNA fragmentation in senescent and cancer cells2022
- Author(s)
  Sugawara S, Okada R, Loo TM, Tanaka H, Miyata K, Chiba M, Kawasaki H, Katoh K, Kaji S, Maezawa Y, Yokote K, Nakayama M, Oshima M, Nagao K, Obuse C, Nagayama S, Takubo K, Nakanishi A, Kanemaki MT, Hara E, Takahashi A.
- Journal Title
  
  Commun Biol
  
  Volume: 5 Issue: 1 Pages: 1420-1420
- DOI
  10.1038/s42003-022-04369-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19550, KAKENHI-PROJECT-22H00457, KAKENHI-PROJECT-20H03572, KAKENHI-PROJECT-21H02957, KAKENHI-PROJECT-22KJ3105, KAKENHI-PROJECT-21K19419, KAKENHI-PROJECT-20K16344, KAKENHI-PROJECT-19H03156, KAKENHI-PLANNED-18H05532, KAKENHI-PLANNED-17H06426, KAKENHI-PUBLICLY-22H05599, KAKENHI-PROJECT-23K23810
[Journal Article] A culture platform to study quiescent hematopoietic stem cells following genome editing2022
- Author(s)
  Shiroshita Kohei、Kobayashi Hiroshi、Watanuki Shintaro、Karigane Daiki、Sorimachi Yuriko、Fujita Shinya、Tamaki Shinpei、Haraguchi Miho、Itokawa Naoki、Aoyama Kazumasa、Koide Shuhei、Masamoto Yosuke、Kobayashi Kenta、Nakamura-Ishizu Ayako、Kurokawa Mineo、Iwama Atsushi、Okamoto Shinichiro、Kataoka Keisuke、Takubo Keiyo
- Journal Title
  
  Cell Reports Methods
  
  Volume: 2 Issue: 12 Pages: 100354-100354
- DOI
  10.1016/j.crmeth.2022.100354
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08431, KAKENHI-PROJECT-22K19550, KAKENHI-PROJECT-22K16298, KAKENHI-PROJECT-21H02957, KAKENHI-PROJECT-21J11016, KAKENHI-PROJECT-22KJ2948, KAKENHI-PROJECT-23K24366
[Journal Article] OGT Regulates Hematopoietic Stem Cell Maintenance via PINK1-Dependent Mitophagy2021
- Author(s)
  Murakami Koichi、 ... 、Takubo Keiyo、Okamoto Shinichiro、Tamura Tomohiko、Nakajima Hideaki
- Journal Title
  
  Cell Reports
  
  Volume: 34 Issue: 1 Pages: 108579-108579
- DOI
  10.1016/j.celrep.2020.108579
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02845, KAKENHI-PROJECT-19K17847, KAKENHI-PROJECT-19K17864
[Journal Article] Characterization of genetically modified mice for phosphoglycerate mutase, a vitally-essential enzyme in glycolysis2021
- Author(s)
  Mikawa T, Shibata E, Shimada M, Ito K, Ito T, Kanda H, Takubo K, Shimada A, Lleonart ME, Inagaki N, Yokode M, Kondoh H
- Journal Title
  
  PLoS One
  
  Volume: 16 Issue: 4 Pages: e0250856-e0250856
- DOI
  10.1371/journal.pone.0250856
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07887, KAKENHI-PROJECT-20K21616, KAKENHI-PROJECT-20K21621, KAKENHI-PROJECT-21H02957, KAKENHI-PROJECT-20K20658
[Journal Article] Obesity accelerates hair thinning by stem cell-centric converging mechanisms2021
- Author(s)
  Morinaga H, Mohri Y, Grachtchouk M, Asakawa K, Matsumura H, Oshima M, Takayama N, Kato T, Nishimori Y, Sorimachi Y,?Takubo K, Suganami T, Iwama A, Iwakura Y, Dlugosz AA, Nishimura EK.
- Journal Title
  
  Nature
  
  Volume: 595 Issue: 7866 Pages: 266-271
- DOI
  10.1038/s41586-021-03624-x
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21621, KAKENHI-PROJECT-18K15114, KAKENHI-PROJECT-18H02637, KAKENHI-PUBLICLY-20H04944, KAKENHI-PUBLICLY-20H05503, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-20H03447, KAKENHI-PROJECT-21H02394, KAKENHI-PROJECT-21H02957, KAKENHI-PROJECT-19K16607
[Journal Article] A Culture Method to Maintain Quiescent Human Hematopoietic Stem Cells2021
- Author(s)
  Kobayashi H,?Takubo K.
- Journal Title
  
  J Vis Exp
  
  Volume: 17 Issue: 171 Pages: 171-171
- DOI
  10.3791/61938
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21621, KAKENHI-PROJECT-21H02957, KAKENHI-PROJECT-21K08431
[Journal Article] p38α plays differential roles in hematopoietic stem cell activity dependent on aging contexts2021
- Author(s)
  Sorimachi Yuriko、Karigane Daiki、Ootomo Yukako、Kobayashi Hiroshi、Morikawa Takayuki、Otsu Kinya、Kubota Yoshiaki、Okamoto Shinichiro、Goda Nobuhito、Takubo Keiyo
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 296 Pages: 100563-100563
- DOI
  10.1016/j.jbc.2021.100563
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21621, KAKENHI-PROJECT-18K08379, KAKENHI-PROJECT-19K17847, KAKENHI-PROJECT-19K17877, KAKENHI-PROJECT-21K08383, KAKENHI-PROJECT-20K07345
[Journal Article] UTX maintains functional integrity of murine hematopoietic system by globally regulating aging-associated genes.2021
- Author(s)
  Sera Y; Nakata Y; Ueda T; Yamasaki N; Koide S; Kobayashi H; Ikeda KI; Kobatake K; Iwasaki M; Oda H; Wolff L; Kanai A; Nagamachi A; Inaba T; Sotomaru Y; Ichinohe T; Koizumi M; Miyakawa Y; Honda ZI; Iwama A; Suda T; Takubo K; Honda H
- Journal Title
  
  Blood.
  
  Volume: 137 Issue: 7 Pages: 908-922
- DOI
  10.1182/blood.2019001044
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07346, KAKENHI-PROJECT-19K22546, KAKENHI-PROJECT-19K17918, KAKENHI-PROJECT-19H05653, KAKENHI-PROJECT-18H02845, KAKENHI-PROJECT-19H03693, KAKENHI-PROJECT-18K08357, KAKENHI-PROJECT-18K18196, KAKENHI-PROJECT-19K17847, KAKENHI-PROJECT-19H01056, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-21K08378, KAKENHI-PROJECT-21K08395
[Journal Article] Phosphoglycerate Mutase Cooperates with Chk1 Kinase to Regulate Glycolysis2020
- Author(s)
  Mikawa Takumi、Shibata Eri、Shimada Midori、Ito Ken、Ito Tomiko、Kanda Hiroaki、Takubo Keiyo、Lleonart Matilde E.、Inagaki Nobuya、Yokode Masayuki、Kondoh Hiroshi
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 7 Pages: 101306-101306
- DOI
  10.1016/j.isci.2020.101306
- NAID
  120006870881
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21503, KAKENHI-PROJECT-20K21616, KAKENHI-PROJECT-18H02681, KAKENHI-PROJECT-18H02845, KAKENHI-PROJECT-19K07887, KAKENHI-PROJECT-20K20658
[Journal Article] Protocol for the Maintenance of Quiescent Murine Hematopoietic Stem Cells2020
- Author(s)
  Kobayashi Hiroshi、Takubo Keiyo
- Journal Title
  
  STAR Protocols
  
  Volume: 1 Issue: 2 Pages: 100078-100078
- DOI
  10.1016/j.xpro.2020.100078
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02845, KAKENHI-PROJECT-19K17847
[Journal Article] Short-chain fatty acids bind to apoptosis-associated speck-like protein to activate inflammasome complex to prevent Salmonella infection2020
- Author(s)
  Tsugawa Hitoshi、Kabe Yasuaki、Kanai Ayaka、Sugiura Yuki、Hida Shigeaki、Taniguchi Shun’ichiro、Takahashi Toshio、Matsui Hidenori、Yasukawa Zenta、Itou Hiroyuki、Takubo Keiyo、Suzuki Hidekazu、Honda Kenya、Handa Hiroshi、Suematsu Makoto
- Journal Title
  
  PLOS Biology
  
  Volume: 18 Issue: 9 Pages: 3000813-3000813
- DOI
  10.1371/journal.pbio.3000813
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07068, KAKENHI-PROJECT-20K06751, KAKENHI-PROJECT-20K07017, KAKENHI-PROJECT-18H02845, KAKENHI-PROJECT-19H03474, KAKENHI-PROJECT-20H03667, KAKENHI-PROJECT-18K06781, KAKENHI-PROJECT-18K06921
[Journal Article] Detection of residual disease in chronic myeloid leukemia utilizing genomic next generation sequencing reveals persistence of differentiated Ph+ B cells but not bone marrow stem/progenitors2020
- Author(s)
  Daiki Karigane, Hidenori Kasahara, ... , Keiyo Takubo.
- Journal Title
  
  Leukemia & Lymphoma
  
  Volume: 62 Issue: 3 Pages: 679-687
- DOI
  10.1080/10428194.2020.1837366
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21621, KAKENHI-PROJECT-18H02845, KAKENHI-PROJECT-20H03461, KAKENHI-PROJECT-19J00502, KAKENHI-PROJECT-19K17847
[Journal Article] Identification and local manipulation of bone marrow vasculature during intravital imaging2020
- Author(s)
  Morikawa Takayuki、Tamaki Shinpei、Fujita Shinya、Suematsu Makoto、Takubo Keiyo
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 6422-6422
- DOI
  10.1038/s41598-020-63533-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02845, KAKENHI-PROJECT-18K08379
[Journal Article] Potential involvement of semaphorin 3A in maintaining intervertebral disc tissue homeostasis2019
- Author(s)
  Mima Y, Suzuki S, Fujii T, Morikawa T, Tamaki S, Takubo K, Shimoda M, Miyamoto T, Watanabe K, Matsumoto M, Nakamura M, Fujita N.
- Journal Title
  
  J Orthop Res
  
  Volume: 37 Issue: 4 Pages: 972-980
- DOI
  10.1002/jor.24258
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02930, KAKENHI-PROJECT-18K08379, KAKENHI-PROJECT-18H02845, KAKENHI-PROJECT-18K19570
[Journal Article] Discrimination of dormant and active hematopoietic stem cells by G0 markers reveals dormancy regulation by cytoplasmic calcium.2019
- Author(s)
  5.Fukushima T, Tanaka Y, Hamey FK, Chang CH, Oki T, Asada S, Hayashi Y, Fujino T, Yonezawa T, Takeda R, Kawabata KC, Fukuyama T, Umemoto T, Takubo K, Takizawa H, Goyama S, Ishihama Y, Honda H, Gottgens B, Kitamura T.
- Journal Title
  
  Cell Rep
  
  Volume: 29 Issue: 12 Pages: 4144-4158
- DOI
  10.1016/j.celrep.2019.11.061
- NAID
  120006892032
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22546, KAKENHI-PROJECT-19K22641, KAKENHI-PROJECT-18H02845, KAKENHI-PROJECT-19H03688, KAKENHI-PROJECT-19H03693, KAKENHI-PROJECT-19J01570, KAKENHI-PROJECT-18K19570
[Journal Article] Fasting-Refeeding Impacts Immune Cell Dynamics and Mucosal Immune Responses2019
- Author(s)
  Nagai M、Noguchi R、Takahashi D、Morikawa T、Koshida K、Komiyama S、Ishihara N、Yamada T、Kawamura YI.、Muroi K、Hattori K、Kobayashi N、Fujimura Y、Hirota M、Matsumoto R、Aoki R、Tamura-Nakano M、Sugiyama M、Katakai T、Sato S、Takubo K、Dohi T、Hase K
- Journal Title
  
  Cell
  
  Volume: 178 Issue: 5 Pages: 1072-1087
- DOI
  10.1016/j.cell.2019.07.047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08379, KAKENHI-PROJECT-19K22528, KAKENHI-PROJECT-19K22532, KAKENHI-PUBLICLY-18H04680, KAKENHI-PROJECT-17H04089, KAKENHI-PROJECT-18H02845, KAKENHI-PROJECT-19H03702, KAKENHI-PROJECT-17KT0055, KAKENHI-PROJECT-18K19570, KAKENHI-PLANNED-18H05417
[Journal Article] ATP turnover and glucose dependency in hematopoietic stem/progenitor cells are increased by proliferation and differentiation2019
- Author(s)
  Watanuki Shintaro、Kobayashi Hiroshi、Sorimachi Yuriko、Yamamoto Masamichi、Okamoto Shinichiro、Takubo Keiyo
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 印刷中 Issue: 1 Pages: 287-294
- DOI
  10.1016/j.bbrc.2019.04.123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16200, KAKENHI-PROJECT-19K17847, KAKENHI-PROJECT-18H02845, KAKENHI-PROJECT-18K19570
[Journal Article] Environmental Optimization Enables Maintenance of Quiescent Hematopoietic Stem Cells Ex Vivo.2019
- Author(s)
  Kobayashi H, Morikawa T, Okinaga A, Hamano F, Hashidate-Yoshida T, Watanuki S, Hishikawa D, Shindou H, Arai F, Kabe Y, Suematsu M, Shimizu T, Takubo K.
- Journal Title
  
  Cell Reports
  
  Volume: 28 Issue: 1 Pages: 145-158
- DOI
  10.1016/j.celrep.2019.06.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06921, KAKENHI-PROJECT-18K08379, KAKENHI-PROJECT-19K22638, KAKENHI-PROJECT-19K17847, KAKENHI-PROJECT-17H04208, KAKENHI-PROJECT-18H02845, KAKENHI-PROJECT-18K19570
[Journal Article] Type I Interferon Delivery by iPSC-Derived Myeloid Cells Elicits Antitumor Immunity via XCR1+ Dendritic Cells.2019
- Author(s)
  Tsuchiya N, Zhang R, Iwama T, Ueda N, Liu T, Tatsumi M, Sasaki Y, Shimoda R, Osako Y, Sawada Y, Kubo Y, Miyashita A, Fukushima S, Cheng Z, Nakaki R, Takubo K, Okada S, Kaneko S, Ihn H, Kaisho T, Nishimura Y, Senju S, Endo I, Nakatsura T, Uemura Y.
- Journal Title
  
  Cell Rep.
  
  Volume: 29 Issue: 1 Pages: 162-175
- DOI
  10.1016/j.celrep.2019.08.086
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08301, KAKENHI-PUBLICLY-19H04813, KAKENHI-PROJECT-17H04088, KAKENHI-PROJECT-18H02845, KAKENHI-PROJECT-17K10717, KAKENHI-PROJECT-17K10806, KAKENHI-PROJECT-18K19570, KAKENHI-PROJECT-17K16345, KAKENHI-PROJECT-18H02641, KAKENHI-PLANNED-16H06498
[Journal Article] Metabolic regulation of hematopoietic and leukemic stem/progenitor cells under homeostatic and stress conditions2017
- Author(s)
  Karigane Daiki、Takubo Keiyo
- Journal Title
  
  International Journal of Hematology
  
  Volume: 106 Issue: 1 Pages: 18-26
- DOI
  10.1007/s12185-017-2261-x
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-26115005, KAKENHI-PROJECT-15H04861, KAKENHI-PROJECT-16K15507
[Journal Article] Quiescence of adult oligodendrocyte precursor cells requires thyroid hormone and hypoxia to activate Runx1.2017
- Author(s)
  Tokumoto Y, Tamaki S, Kabe Y, Takubo K, Suematsu M
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 1019-1019
- DOI
  10.1038/s41598-017-01023-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07011, KAKENHI-PLANNED-26115005, KAKENHI-PROJECT-15H04861, KAKENHI-PROJECT-16K15507
[Journal Article] Abnormal hematopoiesis and hematopoietic stem cell niche2017
- Author(s)
  田久保圭誉、森川隆之、小林央
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 58 Issue: 10 Pages: 1844-1850
- DOI
  10.11406/rinketsu.58.1844
- NAID
  130006132651
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16200, KAKENHI-PLANNED-26115005, KAKENHI-PROJECT-15H04861, KAKENHI-PROJECT-15K10315, KAKENHI-PROJECT-16K15507
[Journal Article] Use of Imaging Techniques to Illuminate Dynamics of Hematopoietic Stem Cells and Their Niches2017
- Author(s)
  Morikawa Takayuki、Takubo Keiyo
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 5 Pages: 62-62
- DOI
  10.3389/fcell.2017.00062
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26115005, KAKENHI-PROJECT-15H04861, KAKENHI-PROJECT-16K15507
[Journal Article] Acquired expression of CblQ367P in mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia2017
- Author(s)
  Nakata Y, Ueda T, Nagamachi A, Yamasaki N, Ikeda KI, Sera Y, Takubo K, Kanai A, Oda H, Sanada M, Ogawa S, Tsuji K, Ebihara Y, Wolff L, Honda ZI, Suda T, Inaba T, Honda H.
- Journal Title
  
  Blood
  
  Volume: 129 Issue: 15 Pages: 2148-2160
- DOI
  10.1182/blood-2016-06-724658
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26115009, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-15J06501, KAKENHI-PROJECT-15K16125, KAKENHI-PROJECT-17K08679, KAKENHI-PROJECT-15H04857, KAKENHI-PROJECT-17J05696, KAKENHI-PROJECT-16K19575
[Journal Article] Hypoxia regulates the hematopoietic stem cell niche.2016
- Author(s)
  Morikawa T, Takubo K.
- Journal Title
  
  Pflugers Arch.
  
  Volume: 468 Issue: 1 Pages: 13-22
- DOI
  10.1007/s00424-015-1743-z
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-26115005, KAKENHI-PROJECT-15H04861, KAKENHI-PROJECT-15K10315
[Journal Article] Setdb1 maintains hematopoietic stem and progenitor cells by restricting the ectopic activation of non-hematopoietic genes.2016
- Author(s)
  Koide S, Oshima M, Takubo K, Yamazaki S, Nitta E, Saraya A, Aoyama K, Kato Y, Miyagi S, Nakajima-Takagi Y, Chiba T, Matsui H, Arai F, Suzuki Y, Kimura H, Nakauchi H, Suda T, Shinkai Y,Iwama A.
- Journal Title
  
  Blood
  
  Volume: 128(5) Issue: 5 Pages: 638-649
- DOI
  10.1182/blood-2016-01-694810
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01513, KAKENHI-PLANNED-26115002, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-15H02544, KAKENHI-PROJECT-16H02661, KAKENHI-PROJECT-15J04258, KAKENHI-PROJECT-26293228, KAKENHI-PROJECT-15K09478, KAKENHI-PROJECT-16K09340, KAKENHI-PROJECT-16K09840, KAKENHI-PROJECT-16K19565, KAKENHI-PROJECT-16K20959
[Journal Article] Loss of Folliculin Disrupts Hematopoietic Stem Cell Quiescence and Homeostasis Resulting in Bone Marrow Failure2016
- Author(s)
  Baba M, Toyama H, Sun L, Takubo K, Suh HC, Hasumi H, Nakamura-Ishizu A, Hasumi Y, Klarmann KD, Nakagata N, Schmidt LS, Linehan WM, Suda T, Keller JR
- Journal Title
  
  Stem Cells
  
  Volume: 34 Issue: 4 Pages: 1068-1082
- DOI
  10.1002/stem.2293
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14370, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15H04975, KAKENHI-PROJECT-26221309
[Journal Article] Regulation of hematopoietic stem cell integrity through p53 and its related factors.2016
- Author(s)
  Yamashita M, Nitta E, Suda T.
- Journal Title
  
  Ann N Y Acad Sci.
  
  Volume: 印刷中 Issue: 1 Pages: 92-100
- DOI
  10.1111/nyas.12986
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461411, KAKENHI-PROJECT-26221309
[Journal Article] How hematopoietic stem/progenitors and their niche sense and respond to infectious stress.2016
- Author(s)
  Kobayashi H, Suda T, Takubo K.
- Journal Title
  
  Exp Hematol.
  
  Volume: 44 Issue: 2 Pages: 92-100
- DOI
  10.1016/j.exphem.2015.11.008
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26115005, KAKENHI-PROJECT-15H04861
[Journal Article] p38α activates purine metabolism to initiate hematopoietic stem/progenitor cell cycling.2016
- Author(s)
  Karigane D, Kobayashi H, Morikawa T, Ootomo Y, Sakai M, Nagamatsu G, Kubota Y, Goda N, Matsumoto M, Nishimura EK, Soga T, Otsu K, Suematsu M, Okamoto S, Suda T, Takubo K.
- Journal Title
  
  Cell Stem Cell
  
  Volume: 19 Pages: 192-294
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-26115001
[Journal Article] Maintenance of the functional integrity of mouse hematopoiesis by EED and promotion of leukemogenesis by EED haploinsufficiency2016
- Author(s)
  Ikeda K-I, Ueda T, Yamasaki N, Nakata Y, Sera Y, Nagamachi A, Miyama T, Kobayashi H, TakuboK, Kanai A, Oda H, Wolff l, Honda Z-1, Ichinohe T, Matsubara A, Suda T, Inaba T, Honda H
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 29454-29454
- DOI
  10.1038/srep29454
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-15J06501, KAKENHI-PROJECT-26293227, KAKENHI-PROJECT-26460391, KAKENHI-PROJECT-15K16125, KAKENHI-PROJECT-16K19575
[Journal Article] Karigane D, Kobayashi H, Morikawa T, Ootomo Y, Sakai M, Nagamatsu G, Kubota Y, Goda N, Matsumoto M, Nishimura EK, Soga T, Otsu K, Suematsu M, Okamoto S, Suda T, Takubo K.2016
- Author(s)
  Karigane D, Kobayashi H, Morikawa T, Ootomo Y, Sakai M, Nagamatsu G, Kubota Y, Goda N, Matsumoto M, Nishimura EK, Soga T, Otsu K, Suematsu M, Okamoto S, Suda T, Takubo K.
- Journal Title
  
  Cell Stem Cell
  
  Volume: 19 Issue: 2 Pages: 192-204
- DOI
  10.1016/j.stem.2016.05.013
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111003, KAKENHI-PLANNED-26115003, KAKENHI-PLANNED-26115005, KAKENHI-PROJECT-26221303, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-15H04851, KAKENHI-PROJECT-15H04861, KAKENHI-PROJECT-15K10315, KAKENHI-PROJECT-16K15507
[Journal Article] Proliferation following tetraploidization regulates the size and number of erythrocytes in the blood flow during medaka development, as revealed by the abnormal karyotype of erythrocytes in the medaka TFDP1 mutant.2015
- Author(s)
  Taimatsu K, Takubo K, Maruyama K, Suda T, Kudo A.
- Journal Title
  
  Dev Dyn.
  
  Volume: 該当なし Issue: 5 Pages: 651-668
- DOI
  10.1002/dvdy.24259
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23689049, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-25340043, KAKENHI-PROJECT-25670788
[Journal Article] Integrative Analysis of the Acquisition of Pluripotency in PGCs reveals the mutually exclusive roles of Blimp-1 and AKT signaling2015
- Author(s)
  Nagamatsu G, Saito S, Takubo K, Suda T.
- Journal Title
  
  Stem Cell Reports
  
  Volume: S2213-6711(15) Issue: 1 Pages: 00150-2
- DOI
  10.1016/j.stemcr.2015.05.007
- Data Source
  KAKENHI-PROJECT-26221309
[Journal Article] CLEC-2 in megakaryocytes is critical for maintenance of hematopoietic stem cells in the bone marrow.2015
- Author(s)
  Nakamura-Ishizu A, Takubo K, Kobayashi H, Suzuki-Inoue K, Suda T.
- Journal Title
  
  J Exp Med.
  
  Volume: 212 Issue: 12 Pages: 2133-46
- DOI
  10.1084/jem.20150057
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461399, KAKENHI-PLANNED-26115005, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-15H04861, KAKENHI-PROJECT-13J40030, KAKENHI-PROJECT-26713035
[Journal Article] Fbxl10 overexpression in murine hematopoietic stemcells induces leukemia involving metabolic activation and upregulation of Nsg22015
- Author(s)
  Ueda T, Nagamachi A, Takubo K, Yamasaki N, Matsui H, Kanai A, Nakata Y, Ikeda K Konuma T, Oda H, Wolff L, Honda Z, Wu X, Helin K, Iwama A, Suda T, Inaba T, Honda H.
- Journal Title
  
  Blood
  
  Volume: 125 Issue: 22 Pages: 3437-3446
- DOI
  10.1182/blood-2014-03-562694
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460391, KAKENHI-PROJECT-15K16125, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-15J06501, KAKENHI-PROJECT-26860735, KAKENHI-PROJECT-26293227
[Journal Article] Bacterial c-di-GMP affects hematopoietic stem/progenitors and their niches through STING.2015
- Author(s)
  Kobayashi H, Kobayashi CI, Nakamura-Ishizu A, Karigane D, Haeno H, Yamamoto KN, Sato T, Ohteki T, Hayakawa Y, Barber GN, Kurokawa M, Suda T, and Takubo K.
- Journal Title
  
  Cell Reports
  
  Volume: 111 Issue: 1 Pages: 71-84
- DOI
  10.1016/j.celrep.2015.02.066
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15150, KAKENHI-PUBLICLY-15H01485, KAKENHI-PUBLICLY-15H01508, KAKENHI-ORGANIZER-26115001, KAKENHI-PLANNED-26115005, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-26253029, KAKENHI-PROJECT-15H04861, KAKENHI-PROJECT-24350087, KAKENHI-PLANNED-26115006
[Journal Article] Telomerase Reverse Transcriptase Has an Extratelomeric Function in Somatic Cell Reprogramming2014
- Author(s)
  Kinoshita T, Nagamatsu G, Saito S, Takubo K, Horimoto K, Suda T.
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 289 Issue: 22 Pages: 15776-15787
- DOI
  10.1074/jbc.m113.536037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J07121, KAKENHI-PLANNED-22130004
[Journal Article] R-spondins/Lgrs expression in tooth development.2014
- Author(s)
  Kawasaki M, Porntaveetus T, Kawasaki K, Oommen S, Otsuka-Tanaka Y, Hishinuma M, Nomoto T, Maeda T, Takubo K, Suda T, Sharpe PT, Ohazama A.
- Journal Title
  
  Dev Dyn.
  
  Volume: 243 Issue: 6 Pages: 844-851
- DOI
  10.1002/dvdy.24124
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23689049, KAKENHI-PROJECT-23792215, KAKENHI-PROJECT-26861545
[Journal Article] Acquired deficiency of A20 results in rapid apoptosis, systemic inflammation, and abnormal hematopoietic stem cell function.2014
- Author(s)
  Nagamachi A, Nakata Y, Ueda T, Yamasaki N, Ebihara Y, Tsuji K, Honda Zi, Takubo K, Suda T, Oda H, Inaba T, Honda H
- Journal Title
  
  PLos One
  
  Volume: 9 Issue: 1 Pages: 1-10
- DOI
  10.1371/journal.pone.0087425
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390252, KAKENHI-PROJECT-23591459, KAKENHI-PROJECT-23689049, KAKENHI-PROJECT-24390272, KAKENHI-PUBLICLY-25118724, KAKENHI-PROJECT-25640065, KAKENHI-PROJECT-25670489, KAKENHI-PROJECT-26293243, KAKENHI-PROJECT-26670511
[Journal Article] Megakaryocytes are essential for HSC quiescence through the production of thrombopoietin.2014
- Author(s)
  Nakamura-Ishizu A, Takubo K, Fujioka M, Suda T.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 454 Pages: 353-357
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23689049
[Journal Article] Telomerase reverse transcriptase has an extratelomeric function in somatic cell reprogramming.2014
- Author(s)
  Kinoshita T, Nagamatsu G, Saito S, Takubo K, Horimoto K, Suda T.
- Journal Title
  
  J Biol Chem.
  
  Volume: 289 Pages: 15776-15787
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689049
[Journal Article] Tet2-mutated myeloid progenitors possess aberrant in vitro self-renewal capacity.2014
- Author(s)
  Kunimoto H, Fukuchi Y, Sakurai M, Takubo K, Okamoto S, Nakajima H.
- Journal Title
  
  Blood.
  
  Volume: 123 Issue: 18 Pages: 2897-2899
- DOI
  10.1182/blood-2014-01-552471
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23689049
[Journal Article] Opening the door for HIF1α tuning.2014
- Author(s)
  Takubo K and Suda T
- Journal Title
  
  Blood
  
  Volume: 123 Issue: 2 Pages: 151-152
- DOI
  10.1182/blood-2013-11-536995
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-23689049, KAKENHI-PUBLICLY-25118724
[Journal Article] Megakaryocytes are essential for HSC quiescence through the production of thrombopoietin2014
- Author(s)
  Nakamura-Ishizu A, Takubo K, Fujioka M, Suda T.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 454(2) Issue: 2 Pages: 353-7
- DOI
  10.1016/j.bbrc.2014.10.095
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J40030, KAKENHI-PLANNED-22130004, KAKENHI-PLANNED-26115005, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-26713035
[Journal Article] Metabolic requirements for the maintenance of self-renewing stem cells.2014
- Author(s)
  Ito K and Suda T
- Journal Title
  
  Nat Rev Mol Cell Biol
  
  Volume: 15 Issue: 4 Pages: 243-256
- DOI
  10.1038/nrm3772
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-26221309
[Journal Article] The IL-2/CD25 Axis Maintains Distinct Subsets of Chronic M yeloid Leukemia-initiating Cells.2014
- Author(s)
  Kobayashi CI, Takubo K, Kobayashi H, Nakamura-Ishizu A, Honda H, Kataoka K, Kumano K, Akiyama H, Sudo T, Kurokawa M, Suda T.
- Journal Title
  
  Blood
  
  Volume: 123 Issue: 16 Pages: 2540-2549
- DOI
  10.1182/blood-2013-07-517847
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-11J04561, KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-23591369, KAKENHI-PROJECT-23689049, KAKENHI-PUBLICLY-25118724, KAKENHI-PROJECT-25640065, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-26461170
[Journal Article] Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7.2013
- Author(s)
  Nagamachi A
- Journal Title
  
  Cancer Cell
  
  Volume: 24 Issue: 3 Pages: 305-317
- DOI
  10.1016/j.ccr.2013.08.011
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-23240125, KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-23390252, KAKENHI-PROJECT-23689049, KAKENHI-PROJECT-24591397, KAKENHI-PUBLICLY-25118724, KAKENHI-PROJECT-25550030, KAKENHI-PROJECT-25640065
[Journal Article] Regulation of glycolysis by Pdk functions as a metabolic checkpoint for cell cycle quiescence in hematopoietic stem cells.2013
- Author(s)
  Takubo K
- Journal Title
  
  Cell Stem Cell
  
  Volume: 12 Issue: 1 Pages: 49-61
- DOI
  10.1016/j.stem.2012.10.011
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001, KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-23590370, KAKENHI-PROJECT-23618011, KAKENHI-PROJECT-23689049, KAKENHI-PROJECT-24240119, KAKENHI-PLANNED-22130004, KAKENHI-PLANNED-22134007, KAKENHI-PUBLICLY-23118527, KAKENHI-PUBLICLY-23130507, KAKENHI-PUBLICLY-24116522
[Journal Article] Roles of the hypoxia response system in hematopoietic and leukemic stem cells.2012
- Author(s)
  Keiyo Takubo
- Journal Title
  
  Int J Hematol.
  
  Volume: 95 Issue: 5 Pages: 478-483
- DOI
  10.1007/s12185-012-1071-4
- NAID
  10030632958
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689049, KAKENHI-PUBLICLY-23118527
[Journal Article] Ex vivo maintenance of hematopoietic stem cells by quiescence induction through Fbxw7&alpha ; overexpression.2011
- Author(s)
  Iriuchishima H, Takubo K, Matsuoka S, Onoyama I, Nakayama KI, Nojima Y, Suda T.
- Journal Title
  
  Blood. 117(8)Epub
  
  Pages: 2373-2377
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790925
[Journal Article] A germ cell specific gene, Prmt5 works as somatic cell reprogramming.2011
- Author(s)
  Nagamatsu G, Kosaka T, Kawasumi M, Kinoshita T, Takubo K, Akiyama H, Sudo T, Kobayashi T, Oya M, Suda T.
- Journal Title
  
  J Biol Chem. [Epub ahead ofprint]
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790925
[Journal Article] Telomerase reverse transcriptase protects ATM-deficient hematopoietic stem cells from ROS-induced apoptosis through a telomere independent mechanism.2011
- Author(s)
  Nitta E, Yamashita M, Hosokawa K, Xian M, Takubo K, Arai F, Nakada S, Suda T.
- Journal Title
  
  Blood [Epub ahead of print]
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790925
[Journal Article] Ataxia-telangiectasia mutated (ATM) deficiency decreases reprogramming efficiency and leads to genomic instability in iPS cells.2011
- Author(s)
  Kinoshita T, Nagamatsu G, Kosaka T, Takubo K, Hotta A, Ellis J, Suda T.
- Journal Title
  
  Biochem Biophys Res Commun. [Epub ahead ofprint]
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790925
[Journal Article] Hemp, an mbt domain-containing protein, plays essential roles in hematopoietic stem cell function and skeletal formation.2011
- Author(s)
  Honda H, Takubo K, Oda H, Kosaki K, Tazaki T, Yamasaki N, Miyazaki K, Moore KA, Honda Z, Suda T, Lemischka IR.
- Journal Title
  
  Proc Natl Acad Sci USA. 108(6)Epub
  
  Pages: 2468-2473
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790925
[Journal Article] Acquisition of Go state by CD34-positive cord blood cells after bone marrow transplantation.2010
- Author(s)
  Shima H, Takubo K, Tago N, Iwasaki H, Arai F, Takahashi T, Suda T.
- Journal Title
  
  Exp Hematol. 38(12)Epub
  
  Pages: 1231-1240
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790925
[Journal Article] Regulation of the HIF-1alpha level is essential for hematopoietic stem cells.2010
- Author(s)
  Keiyo Takubo
- Journal Title
  
  Cell Stem Cell
  
  Volume: 7 Pages: 391-402
- NAID
  40018846661
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21028018
[Journal Article] Regulation of the HIF-1alpha level is essential for hematopoietic stem cells.2010
- Author(s)
  Takubo K, et al.
- Journal Title
  
  Cell Stem Cell
  
  Volume: 7 Pages: 391-402
- NAID
  40018846661
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22130004
[Journal Article] Regulation of the HIF-1alpha level is essential for hematopoietic stem cells.2010
- Author(s)
  Keiyo Takubo
- Journal Title
  
  Cell Stem Cell
  
  Volume: 7 Pages: 391-402
- NAID
  40018846661
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790925
[Journal Article] von Hippel-Lindau protein regulates transition from the fetal to the adult circulatory system in retina.2010
- Author(s)
  Kurihara T, Kubota Y, Ozawa Y, Takubo K, Noda K, Simon MC, Johnson RS, Suematsu M, Tsubota K, Ishida S, Goda N, Suda T, Okano H.
- Journal Title
  
  Development 137(9)
  
  Pages: 1563-1571
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790925
[Journal Article] Regulation of the HIF-1alpha level is essential for hematopoietic stem cells.2010
- Author(s)
  Takubo K, Goda N, Yamada W, Iriuchishima H, Ikeda E, Kubota Y, Shima H, Johnson RS, Hirao A, Suematsu M, Suda T.
- Journal Title
  
  Cell Stem Cell. 7(3)
  
  Pages: 391-402
- NAID
  40018846661
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790925
[Journal Article] Cadherin-based adhesion is a potential target for niche manipulation to protect hematopoietic stem cells in adult bone marrow.2010
- Author(s)
  Hosokawa K, Arai F, Yoshihara H, Iwasaki H, Hembree M, Yin T, Nakamura Y, Gomei Y, Takubo K, Shiama H, Matsuoka S, Li L, Suda T.
- Journal Title
  
  Cell Stem Cell. 6(3)
  
  Pages: 194-198
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790925
[Journal Article] 酸素代謝による造血幹細胞制御2009
- Author(s)
  田久保圭誉
- Journal Title
  
  臨床血液 51
  
  Pages: 95-103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790925
[Journal Article] 酸素代謝による造血幹細胞制御2009
- Author(s)
  田久保圭誉
- Journal Title
  
  臨床血液 51
  
  Pages: 95-103
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21028018
[Journal Article] Craniofacial malformation in R-spondin2 knockout mice.2009
- Author(s)
  Yamada W, Nagao K, Horikoshi K, Fujikura A, Ikeda E, Inagaki Y, Kakitani M, Tomizuka K, Miyazaki H, Suda T, Takubo K.
- Journal Title
  
  Biochem Biophys Res Commun. 381(3)Epub
  
  Pages: 453-458
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790925
[Journal Article] M-CSF inhibition selectively targets pathological angiogenesis and lymphangiogenesis.2009
- Author(s)
  Kubota Y, Takubo K, Shimizu T, Ohno H, Kishi K, Shibuya M, Saya H, Suda T.
- Journal Title
  
  J Exp Med. 206(5)Epub
  
  Pages: 1089-1102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790925
[Journal Article] Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL2008
- Author(s)
  Matsuoka S, Oike Y, Onoyama I, Iwama A, Arai F, Takubo K, Mashimo Y, Oguro H, Nitta E, Ito K, Miyamoto K, Yoshiwara H, Hosokawa K, Nakamura Y, Gomei Y, Iwasaki H, Hayashi Y, Matsuzaki Y, Nakayama K, Ikeda Y, Hata A, Chiba S, Nakayama KI, Suda T
- Journal Title
  
  Genes Dev 22
  
  Pages: 986-991
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16002011
[Journal Article] Stem cell defects in ATM-deficient undifferentiated spermatogonia through DNA damage-induced cell cycle arrest2008
- Author(s)
  Takubo K, Ohmura M, Azuma M, Nagamatsu G, Yamada Y, Arai F, Hirao A, Suda T
- Journal Title
  
  Cell Stem Cell 2
  
  Pages: 170-182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16002011
[Journal Article] Stem cell defects in ATM-deficient undifferentiated spermatogonia through DNA damage-induced cell cycle arrest.2008
- Author(s)
  Takubo K., et. al.
- Journal Title
  
  Cell Stem Cell 2
  
  Pages: 170-182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16002011
[Journal Article] Foxo3a is essential for maintenance of the hematopoietic stem cell pool2007
- Author(s)
  Miyamoto K, Y. Araki K, Naka K, Arai F, Takubo K, Yamazaki S, Matsuoka S, Miyamoto T, Ito K, Ohmura M, Chen C, Hosokawa K, Nakauchi H, Nakayama K, Nakayama K, Harada M, Motoyama N, Suda T, Hirao A
- Journal Title
  
  Cell Stem Cell 1
  
  Pages: 101-112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16002011
[Journal Article] Thrombopoietin/Mpl signaling regulates hematopoietic stem cell quiescence and interaction with the osteoblastic niche2007
- Author(s)
  Yoshihara H, Arai F, Hosokawa K, Hagiwara T, Takubo K, Nakamura Y, Gomei Y, Iwasaki H, Matsuoka S, Miyazaki H, Takahashi T, Suda T
- Journal Title
  
  Cell Stem Cell 1
  
  Pages: 685-697
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16002011
[Journal Article] Reactive oxygen species induce chondrocyte hypertrophy in endochondral ossification.2007
- Author(s)
  Morita K, Miyamoto T, Fujita N, Kubota Y, Ito K, Takubo K, Miyamoto K, Ninomiya K, Suzuki T, Iwasaki R, Yagi M, Takaishi H, Toyama Y, Suda T
- Journal Title
  
  J Exp Med 204
  
  Pages: 1613-1623
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16002011
[Journal Article] Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells.2006
- Author(s)
  Ito K, Hirao A, Arai F, Takubo K, Matsuoka S, Miyamoto K, Ohmura M, Naka K, Hosokawa K, Ikeda Y, Suda T
- Journal Title
  
  Nature Med 12
  
  Pages: 446-451
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16002011
[Journal Article] Tie2/Angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche.2004
- Author(s)
  Arai F, Hirao A, Ohmura M, Sato H, Matsuoka S, Takubo K, Ito K, Koh GY, Suda T
- Journal Title
  
  Cell 118
  
  Pages: 149-161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16002011
[Journal Article] Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells.2004
- Author(s)
  Ito K, Hirao A, Arai F, Matsuoka S, Takubo K, Nakagata N, Ikeda Y, Tak W. Mak, Suda T
- Journal Title
  
  Nature 431
  
  Pages: 997-1002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16002011
[Presentation] The Pbx1-G9a axis dysregulates lineage output of aged hematopoietic stem cells2023
- Author(s)
  Hiroshi Kobayashi, Shintaro Watanuki, Yusuke Shiozawa, Naoya Takayama, Seishi Ogawa, Atsushi Iwama, Keiyo Takubo
- Organizer
  第20回幹細胞シンポジウム
- Data Source
  KAKENHI-PROJECT-22K19550
[Presentation] 神経伝達物質による造血幹細胞のホーミング制御2023
- Author(s)
  田久保圭誉
- Organizer
  第4回血液疾患領域Web研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] Nociceptive nerves facilitate hematopoietic stem and progenitor cell homing to bone marrow by regulating microcirculation2023
- Author(s)
  Shinya Fujita, Takayuki Morikawa, Keisuke Kataoka, Keiyo Takubo
- Organizer
  第20回幹細胞シンポジウム
- Data Source
  KAKENHI-PROJECT-22K19550
[Presentation] 加齢造血幹細胞の「強さ」を支える代謝リプログラミング2023
- Author(s)
  田久保圭誉
- Organizer
  実験動物中央研究所特別セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] 侵害受容神経は骨髄微小循環を制御し造血幹前駆細胞のホーミングを促す2023
- Author(s)
  藤田進也, 森川隆之, 片岡圭亮, 田久保圭誉
- Organizer
  低酸素研究会2023
- Data Source
  KAKENHI-PROJECT-22K19550
[Presentation] 骨髄環境のイメージング2023
- Author(s)
  田久保圭誉
- Organizer
  第85回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-22K19550
[Presentation] 侵害受容神経による造血幹・前駆細胞のホーミング制御2023
- Author(s)
  田久保圭誉
- Organizer
  日本再生医療学会第3回科学シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-22K19550
[Presentation] 神経シグナルによる造血幹・前駆細胞のホーミング制御2023
- Author(s)
  田久保圭誉
- Organizer
  第22回日本再生医療学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-22K19550
[Presentation] 骨髄環境のイメージング2023
- Author(s)
  田久保圭誉
- Organizer
  第85回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] 神経シグナルによる造血幹・前駆細胞のホーミング制御2023
- Author(s)
  田久保圭誉
- Organizer
  第22回日本再生医療学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] 加齢造血幹細胞の「強さ」を支える代謝リプログラミング2023
- Author(s)
  田久保圭誉
- Organizer
  実験動物中央研究所特別セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-22K19550
[Presentation] The Pbx1-G9a axis dysregulates lineage output of aged hematopoietic stem cells2023
- Author(s)
  Hiroshi Kobayashi, Shintaro Watanuki, Yusuke Shiozawa, Naoya Takayama, Seishi Ogawa, Atsushi Iwama, Keiyo Takubo
- Organizer
  第20回幹細胞シンポジウム
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] 侵害受容神経による造血幹・前駆細胞のホーミング制御2023
- Author(s)
  田久保圭誉
- Organizer
  日本再生医療学会第3回科学シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] 侵害受容神経は骨髄微小循環を制御し造血幹前駆細胞のホーミングを促す2023
- Author(s)
  藤田進也, 森川隆之, 片岡圭亮, 田久保圭誉
- Organizer
  低酸素研究会2023
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] 間葉系幹細胞特異的p53欠損は幹細胞特性を変化させて未分化軟部肉腫を発症する2023
- Author(s)
  反町優理子, 小林央, 合田亘人, 田久保圭誉
- Organizer
  癌と代謝研究会2023
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] 間葉系幹細胞特異的p53欠損は幹細胞特性を変化させて未分化軟部肉腫を発症する2023
- Author(s)
  反町優理子, 小林央, 合田亘人, 田久保圭誉
- Organizer
  癌と代謝研究会2023
- Data Source
  KAKENHI-PROJECT-22K19550
[Presentation] Nociceptive nerves facilitate hematopoietic stem and progenitor cell homing to bone marrow by regulating microcirculation2023
- Author(s)
  Shinya Fujita, Takayuki Morikawa, Keisuke Kataoka, Keiyo Takubo
- Organizer
  第20回幹細胞シンポジウム
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] 骨髄の微小循環と造血幹細胞のエイジング2023
- Author(s)
  小林央, 田久保圭誉
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] 骨髄の微小循環と造血幹細胞のエイジング2023
- Author(s)
  小林央, 田久保圭誉
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K19550
[Presentation] 神経伝達物質による造血幹細胞のホーミング制御2023
- Author(s)
  田久保圭誉
- Organizer
  第4回血液疾患領域Web研究会
- Invited
- Data Source
  KAKENHI-PROJECT-22K19550
[Presentation] Real-time ATP analysis reveals stress-dependent Pfkfb3 modification and its effect on hematopoiesis2022
- Author(s)
  綿貫慎太郎、小林央、杉浦悠毅、山本正道、城下郊平、反町優理子、小出周平、大島基彦、西山晃、村上紘一、原口美帆、玉置新平、山本雄広、岡本真一郎、田村智彦、末松誠、岩間厚志、田久保圭誉
- Organizer
  第84回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] Hematopoietic stem cells acquire robust mitochondrial metabolic plasticity by increasing Sdhaf1 protein levels during aging2022
- Author(s)
  Shintaro Watanuki, Hiroshi Kobayashi, Keiyo Takubo
- Organizer
  第19回幹細胞シンポジウム
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] PFKFB3はストレス毎に異なる修飾を介して造血幹細胞機能を維持する2022
- Author(s)
  綿貫慎太郎、小林央、田久保圭誉
- Organizer
  低酸素研究会2022
- Data Source
  KAKENHI-PROJECT-22K19550
[Presentation] Nociceptive nerves facilitate hematopoietic cell homing to bone marrow by tuning microcirculation2022
- Author(s)
  Shinya Fujita, Takayuki Morikawa, Keisuke Kataoka, Keiyo Takubo
- Organizer
  第84回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-22K19550
[Presentation] Mesenchymal loss of p53 alters stem cell capacity and models human fibrosarcoma2022
- Author(s)
  Yuriko Sorimachi, Hiroshi Kobayashi, Nobuhito Goda, Keiyo Takubo
- Organizer
  Hemato-Retreat2022
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] 造血幹細胞のATP濃度制御とエイジング2022
- Author(s)
  田久保圭誉
- Organizer
  第8回がんと代謝研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] 骨髄内環境を再現した造血幹細胞培養とその応用2022
- Author(s)
  小林央、田久保圭誉
- Organizer
  第21回日本再生医療学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] Real-time ATP analysis reveals stress-dependent Pfkfb3 modification and its effect on hematopoiesis2022
- Author(s)
  綿貫慎太郎、小林央、杉浦悠毅、山本正道、城下郊平、反町優理子、小出周平、大島基彦、西山晃、村上紘一、原口美帆、玉置新平、山本雄広、岡本真一郎、田村智彦、末松誠、岩間厚志、田久保圭誉
- Organizer
  第84回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-22K19550
[Presentation] Optimized culture condition that improves post-editing function of hematopoietic stem cells2022
- Author(s)
  Kohei Shiroshita, Hiroshi Kobayashi, Keisuke Kataoka, Keiyo Takubo
- Organizer
  第84回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] Hematopoietic stem cells acquire robust mitochondrial metabolic plasticity by increasing Sdhaf1 protein levels during aging2022
- Author(s)
  Shintaro Watanuki, Hiroshi Kobayashi, Keiyo Takubo
- Organizer
  Hemato-Retreat2022
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] 骨髄内環境を再現した造血幹細胞培養とその応用2022
- Author(s)
  小林央、田久保圭誉
- Organizer
  第21回日本再生医療学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K21621
[Presentation] Nociceptive nerves facilitate hematopoietic cell homing to bone marrow by tuning microcirculation2022
- Author(s)
  Shinya Fujita, Takayuki Morikawa, Keisuke Kataoka, Keiyo Takubo
- Organizer
  第84回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] 造血幹細胞のPFKFB3依存的解糖系流量調節2022
- Author(s)
  綿貫慎太郎、小林央、田久保圭誉
- Organizer
  第8回がんと代謝研究会
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] An optimized culture condition for hematopoietic stem cells that improves the gene editing efficiency and post-editing function2022
- Author(s)
  Kohei Shiroshita, Hiroshi Kobayashi, Daiki Karigane, Keiyo Takubo
- Organizer
  ISEH2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19550
[Presentation] 造血幹細胞のPFKFB3依存的解糖系流量調節2022
- Author(s)
  綿貫慎太郎、小林央、田久保圭誉
- Organizer
  第8回がんと代謝研究会
- Data Source
  KAKENHI-PROJECT-22K19550
[Presentation] 造血幹細胞の遺伝子編集前培養はRNPの核内輸送を増強する2022
- Author(s)
  城下郊平、小林央、田久保圭誉
- Organizer
  第7回ゲノム編集学会
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] 造血幹細胞の代謝プログラムを明らかにする試み2022
- Author(s)
  田久保圭誉
- Organizer
  iSeminar
- Invited
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] Optimized culture condition that improves post-editing function of hematopoietic stem cells2022
- Author(s)
  Kohei Shiroshita, Hiroshi Kobayashi, Keisuke Kataoka, Keiyo Takubo
- Organizer
  第84回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-22K19550
[Presentation] 造血幹細胞のATP濃度制御とエイジング2022
- Author(s)
  田久保圭誉
- Organizer
  第8回がんと代謝研究会
- Invited
- Data Source
  KAKENHI-PROJECT-22K19550
[Presentation] An optimized culture condition for hematopoietic stem cells that improves the gene editing efficiency and post-editing function2022
- Author(s)
  Kohei Shiroshita, Hiroshi Kobayashi, Daiki Karigane, Keiyo Takubo
- Organizer
  ISEH2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] Mesenchymal loss of p53 alters stem cell capacity and models human fibrosarcoma2022
- Author(s)
  Yuriko Sorimachi, Hiroshi Kobayashi, Nobuhito Goda, Keiyo Takubo
- Organizer
  第19回幹細胞シンポジウム
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] PFKFB3はストレス毎に異なる修飾を介して造血幹細胞機能を維持する2022
- Author(s)
  綿貫慎太郎、小林央、田久保圭誉
- Organizer
  低酸素研究会2022
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] 単一細胞リアルタイム代謝解析に基づく加齢造血幹細胞の代謝変化の解析2021
- Author(s)
  田久保圭誉
- Organizer
  CCVAA2021
- Invited
- Data Source
  KAKENHI-PROJECT-20K21621
[Presentation] Single-cell, real-time analysis of hematopoietic stem cell metabolism during aging2021
- Author(s)
  Keiyo Takubo
- Organizer
  第83回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] Single-cell, real-time analysis of hematopoietic stem cell metabolism during aging2021
- Author(s)
  Keiyo Takubo
- Organizer
  第83回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K21621
[Presentation] 単一細胞リアルタイム代謝解析に基づく加齢造血幹細胞の代謝変化の解析2021
- Author(s)
  田久保圭誉
- Organizer
  CCVAA2021
- Invited
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] Nitric oxide-dependent vasodilation maintains the physiological oxygen levels in bone marrow and allows local crawling of hematopoietic stem cells2021
- Author(s)
  Takayuki Morikawa, Keiyo Takubo
- Organizer
  ISEH2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] Nitric oxide-dependent vasodilation maintains physiological hypoxia and local crawling of hematopoietic stem cell in bone marrow2021
- Author(s)
  Takayuki Morikawa, Shinya Fujita, Toshitada Yoshihara, Seiji Tobita, Keiyo Takubo
- Organizer
  第18回幹細胞シンポジウム
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] Real-Time ATP Analysis Reveals Thymidine Requirement of Quiescent Hematopoietic Stem Cells2021
- Author(s)
  Shintaro Watanuki, Hiroshi Kobayashi, Masamichi Yamamoto, Keiyo Takubo
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] 骨髄の生理的低酸素環境の形成機構と造血幹細胞制御2021
- Author(s)
  田久保圭誉
- Organizer
  第94回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K21621
[Presentation] 造血幹細胞の解糖系代謝可塑性と造血制御2021
- Author(s)
  綿貫慎太郎、小林央、田久保圭誉
- Organizer
  第94回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] 培養環境の最適化による造血幹細胞の体外での静止期維持2021
- Author(s)
  小林央、森川隆之、沖長あゆみ、浜野文三江、橋立智美、綿貫慎太郎、菱川大介、進藤英雄、新井文用、加部泰明、末松誠、清水孝雄、田久保圭誉
- Organizer
  第16回麒麟塾
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] 造血幹細胞機能と特性維持に最適化した新規遺伝子編集法2021
- Author(s)
  Kohei Shiroshita, Hiroshi Kobayashi, Keisuke Kataoka, Keiyo Takubo
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] Environmental optimization to maintain the function of hematopoietic stem cells after genome editing2021
- Author(s)
  Kohei Shiroshita, Hiroshi Kobayashi, Keiyo Takubo
- Organizer
  第18回幹細胞シンポジウム
- Data Source
  KAKENHI-PROJECT-20K21621
[Presentation] Nitric oxide-dependent vasodilation maintains the physiological oxygen levels in bone marrow and allows local crawling of hematopoietic stem cells2021
- Author(s)
  Takayuki Morikawa, Keiyo Takubo
- Organizer
  ISEH2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21621
[Presentation] 培養環境の最適化による造血幹細胞の体外での静止期維持2021
- Author(s)
  小林央、森川隆之、沖長あゆみ、浜野文三江、橋立智美、綿貫慎太郎、菱川大介、進藤英雄、新井文用、加部泰明、末松誠、清水孝雄、田久保圭誉
- Organizer
  第16回麒麟塾
- Data Source
  KAKENHI-PROJECT-20K21621
[Presentation] Non-neuronal acetylcholine in bone marrow derives from hematopoietic cells and regulates B cell dynamics2021
- Author(s)
  Shinya Fujita, Takayuki Morikawa, Yuki Sugiura, Hishiki Takako, Maiko Sezaki, Hitoshi Takizawa, Keisuke Kataoka, Makoto Suematsu, Keiyo Takubo
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] Nitric oxide-dependent vasodilation maintains physiological hypoxia and local crawling of hematopoietic stem cell in bone marrow2021
- Author(s)
  Takayuki Morikawa, Shinya Fujita, Toshitada Yoshihara, Seiji Tobita, Keiyo Takubo
- Organizer
  第18回幹細胞シンポジウム
- Data Source
  KAKENHI-PROJECT-20K21621
[Presentation] Environmental optimization to maintain the function of hematopoietic stem cells after genome editing2021
- Author(s)
  Kohei Shiroshita, Hiroshi Kobayashi, Keiyo Takubo
- Organizer
  第18回幹細胞シンポジウム
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] Real-Time ATP Analysis Reveals Thymidine Requirement of Quiescent Hematopoietic Stem Cells2021
- Author(s)
  Shintaro Watanuki, Hiroshi Kobayashi, Masamichi Yamamoto, Keiyo Takubo
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20K21621
[Presentation] Non-neuronal acetylcholine in the bone marrow regulates B cell differentiation2021
- Author(s)
  Shinya Fujita, Takayuki Morikawa, Yuki Sugiura, Hishiki Takako, Maiko Sezaki, Hitoshi Takizawa, Keisuke Kataoka, Makoto Suematsu, Keiyo Takubo
- Organizer
  第18回幹細胞シンポジウム
- Data Source
  KAKENHI-PROJECT-20K21621
[Presentation] 造血幹細胞機能と特性維持に最適化した新規遺伝子編集法2021
- Author(s)
  Kohei Shiroshita, Hiroshi Kobayashi, Keisuke Kataoka, Keiyo Takubo
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20K21621
[Presentation] 加齢造血変化をもたらす造血幹細胞の代謝リプログラミング2021
- Author(s)
  田久保圭誉
- Organizer
  第63回日本老年医学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] 骨髄の生理的低酸素環境の形成機構と造血幹細胞制御2021
- Author(s)
  田久保圭誉
- Organizer
  第94回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] 造血幹細胞の解糖系代謝可塑性と造血制御2021
- Author(s)
  綿貫慎太郎、小林央、田久保圭誉
- Organizer
  第94回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K21621
[Presentation] Non-neuronal acetylcholine in bone marrow derives from hematopoietic cells and regulates B cell dynamics2021
- Author(s)
  Shinya Fujita, Takayuki Morikawa, Yuki Sugiura, Hishiki Takako, Maiko Sezaki, Hitoshi Takizawa, Keisuke Kataoka, Makoto Suematsu, Keiyo Takubo
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20K21621
[Presentation] 造血幹細胞に最適化した遺伝子編集法の確立とそれに基づく代謝特性解析2021
- Author(s)
  城下郊平、小林央、田久保圭誉
- Organizer
  第6回ゲノム編集学会
- Data Source
  KAKENHI-PROJECT-20K21621
[Presentation] 加齢造血変化をもたらす造血幹細胞の代謝リプログラミング2021
- Author(s)
  田久保圭誉
- Organizer
  第63回日本老年医学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K21621
[Presentation] 造血幹細胞に最適化した遺伝子編集法の確立とそれに基づく代謝特性解析2021
- Author(s)
  城下郊平、小林央、田久保圭誉
- Organizer
  第6回ゲノム編集学会
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] Non-neuronal acetylcholine in the bone marrow regulates B cell differentiation2021
- Author(s)
  Shinya Fujita, Takayuki Morikawa, Yuki Sugiura, Hishiki Takako, Maiko Sezaki, Hitoshi Takizawa, Keisuke Kataoka, Makoto Suematsu, Keiyo Takubo
- Organizer
  第18回幹細胞シンポジウム
- Data Source
  KAKENHI-PROJECT-21H02957
[Presentation] Metabolic regulation of hematopoietic stem cell function2017
- Author(s)
  Keiyo Takubo
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  浜松アクトシティコングレスセンター
- Year and Date
  2017-03-29
- Invited
- Data Source
  KAKENHI-PROJECT-15H04861
[Presentation] Metabolic regulation of hematopoietic stem cell function2017
- Author(s)
  Keiyo Takubo
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  浜松アクトシティコングレスセンター
- Year and Date
  2017-03-29
- Invited
- Data Source
  KAKENHI-PLANNED-26115005
[Presentation] Metabolic regulation of hematopoietic stem cells in the bone marrow niche.2015
- Author(s)
  Takubo K.
- Organizer
  Stem Therapy Seminar series at Lund Stem Cell Center
- Place of Presentation
  Lund, Sweden
- Year and Date
  2015-06-29
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04861
[Presentation] Metabolic regulation of hematopoietic stem cells in the bone marrow niche.2015
- Author(s)
  Takubo K.
- Organizer
  Stem Therapy Seminar series at Lund Stem Cell Center
- Place of Presentation
  Lund, Sweden
- Year and Date
  2015-06-29
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26115005
[Presentation] 造血幹細胞ニッチによる造血恒常性制御2014
- Author(s)
  田久保圭誉
- Organizer
  第13回熊本血液感染免疫フォーラム
- Place of Presentation
  ANAクラウンプラザホテル熊本
- Year and Date
  2014-09-04
- Invited
- Data Source
  KAKENHI-PLANNED-26115005
[Presentation] Megakaryocyte: a novel niche cell for hematopoietic stem cells2014
- Author(s)
  Keiyo Takubo
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-16
- Data Source
  KAKENHI-PLANNED-26115005
[Presentation] ニッチによる造血幹細胞のエネルギー代謝特性制御2014
- Author(s)
  田久保圭誉
- Organizer
  日本生化学会関東支部例会
- Place of Presentation
  茨城大学水戸キャンパス
- Year and Date
  2014-06-13
- Invited
- Data Source
  KAKENHI-PUBLICLY-25118724
[Presentation] 造血器腫瘍による骨髄ニッチの変容制御2014
- Author(s)
  田久保圭誉
- Organizer
  第87回日本内分泌学会学術総会
- Place of Presentation
  福岡サンパレス
- Year and Date
  2014-04-26
- Invited
- Data Source
  KAKENHI-PUBLICLY-25118724
[Presentation] Megakaryocyte: a novel niche cell for hematopoietic stem cells2014
- Author(s)
  Keiyo Takubo
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-27
- Invited
- Data Source
  KAKENHI-PLANNED-26115005
[Presentation] Stress response signalingin maintenance ofhematopoietic stem cells2014
- Author(s)
  Keiyo Takubo
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-11-01
- Invited
- Data Source
  KAKENHI-PLANNED-26115005
[Presentation] 造血幹細胞ニッチによる造血恒常性制御2014
- Author(s)
  田久保圭誉
- Organizer
  第13回熊本血液感染免疫フォーラム
- Place of Presentation
  ANAクラウンプラザホテル熊本
- Year and Date
  2014-09-05
- Invited
- Data Source
  KAKENHI-PUBLICLY-25118724
[Presentation] 造血幹・前駆細胞の解糖系代謝によるストレス造血制御2014
- Author(s)
  田久保圭誉
- Organizer
  第2回がんと代謝研究会
- Place of Presentation
  東京理科大学
- Year and Date
  2014-07-11
- Invited
- Data Source
  KAKENHI-PLANNED-26115005
[Presentation] 巨核球分化シグナルと造血幹細胞機能の連関2012
- Author(s)
  田久保　圭誉
- Organizer
  新学術領域研究「細胞運命制御」班会議
- Place of Presentation
  広島
- Year and Date
  2012-06-06
- Data Source
  KAKENHI-PUBLICLY-23118527
[Presentation] 超免疫不全マウスを用いた骨髄腫ニッチの解析2011
- Author(s)
  田久保圭誉
- Organizer
  厚生労働省がん研究開発費「多発性骨髄腫の病態解明と分子基盤に基づく効果的な分子標的療法の確立に関する研究」班平成22年度第2回班会議
- Place of Presentation
  慶應義塾大学薬学部(東京)
- Year and Date
  2011-02-05
- Data Source
  KAKENHI-PROJECT-21790925
[Presentation] NOGマウスを用いた多発性骨髄腫と骨髄腫ニッチへのBendamustineの効果の解析2011
- Author(s)
  田久保圭誉
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(名古屋)
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PUBLICLY-23118527
[Presentation] 造血幹細胞の新たな幹細胞性としてのエネルギー代謝制御機構2011
- Author(s)
  田久保圭誉
- Organizer
  国立感染症研究所血液・安全性研究部セミナー
- Place of Presentation
  国立感染症研究所(東京)
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-23689049
[Presentation] Anaerobic Metabolism Maintains Quiescence of Hematopoietic Stem Cell2011
- Author(s)
  Keiyo Takubo
- Organizer
  USA-Japan Cooperative Cancer Research Workshop
- Place of Presentation
  湘南国際村研修センター(葉山)
- Year and Date
  2011-02-25
- Data Source
  KAKENHI-PROJECT-21790925
[Presentation] Pdk-mediated Modulation of Cell Cycle of Long-Term Hematopoietic Stem Cells2011
- Author(s)
  田久保圭誉, 入内島裕乃, 須田年生
- Organizer
  第8回がんとハイポキシア研究会
- Place of Presentation
  札幌
- Year and Date
  2011-01-29
- Data Source
  KAKENHI-PROJECT-21790925
[Presentation] Glycolysis by Pdk maintains the quiescence of hematopoietic stem cells2011
- Author(s)
  Keiyo Takubo
- Organizer
  DiSCUSS Meeting
- Place of Presentation
  MPI-CBG(ドイツドレスデン)
- Year and Date
  2011-12-06
- Data Source
  KAKENHI-PROJECT-23689049
[Presentation] Anaerobic Metabolism Maintains Quiescence of Hematopoietic Stem cell2011
- Author(s)
  Keiyo Takubo
- Organizer
  USA-Japan Cooperative Cancer Research Workshop
- Place of Presentation
  湘南国際村研修センター(葉山)
- Year and Date
  2011-02-25
- Data Source
  KAKENHI-PUBLICLY-21028018
[Presentation] Pdk-mediated Modulation of Cell Cycle of Long-Term Hematopoietic Stem Cells2011
- Author(s)
  田久保圭誉
- Organizer
  第8回がんとハイポキシア研究会
- Place of Presentation
  北海道大学医学部(札幌)
- Year and Date
  2011-01-29
- Data Source
  KAKENHI-PROJECT-21790925
[Presentation] Pdkを介した代謝プログラムによる造血幹細胞維持とその操作2011
- Author(s)
  田久保圭誉
- Organizer
  新学術領域「細胞運命制御」若手の会
- Place of Presentation
  軽井沢プリンスホテル(軽井沢)
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PUBLICLY-23118527
[Presentation] Anaerobic energy metabolism regulates hematopoietic stem cell quiescence2011
- Author(s)
  Keiyo Takubo
- Organizer
  3rd Else Kroner--Fresenius Symposium on Molecular Mechanisms of Adult Stem Cell Aging
- Place of Presentation
  Reisensburg Castle(ドイツギュンツブルグ)
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-23689049
[Presentation] 超免疫不全マウスを用いた骨髄腫ニッチの解析2011
- Author(s)
  田久保圭誉
- Organizer
  厚生労働省がん研究開発費「多発性骨髄腫の病態解明と分子基盤に基づく効果的な分子標的療法の確立に関する研究」班平成22年度第2回班会議
- Place of Presentation
  慶應義塾大学薬学部(東京)
- Year and Date
  2011-02-05
- Data Source
  KAKENHI-PUBLICLY-21028018
[Presentation] Glycolysis maintains quiescence of hematopoietic stem cells2011
- Author(s)
  Keiyo Takubo
- Organizer
  Keio University School of Medicine Global COE Program International Symposium 2011 "Cutting Edge of Stem Cell Medicine"
- Place of Presentation
  慶應義塾大学医学部(東京)
- Year and Date
  2011-05-16
- Data Source
  KAKENHI-PUBLICLY-23118527
[Presentation] Glycolysis maintains quiescence of hematopoietic stem cells2011
- Author(s)
  Keiyo Takubo
- Organizer
  Keio University School of Medicine Global COE Program International Symposium 2011 "Cutting Edge of Stem Cell Medicine"
- Place of Presentation
  慶應義塾大学医学部(東京)
- Year and Date
  2011-05-16
- Data Source
  KAKENHI-PROJECT-23689049
[Presentation] NOGマウスを用いた多発性骨髄腫と骨髄腫ニッチへのBendamustineの効果の解析2011
- Author(s)
  田久保圭誉
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(名古屋)
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-23689049
[Presentation] Glycolytic Energy Metabolism by Pdk Maintains Quiescence of Hematopoietic Stem Cells2011
- Author(s)
  田久保圭誉
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋国際会議場(名古屋)
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-23689049
[Presentation] Glycolysis by Pdk maintains the quiescence of hematopoietic stem cells2011
- Author(s)
  Keiyo Takubo
- Organizer
  DiSCUSS Meeting
- Place of Presentation
  MPI-CBG(ドイツドレスデン)
- Year and Date
  2011-12-06
- Data Source
  KAKENHI-PUBLICLY-23118527
[Presentation] Quiescence of stem cells in the hypoxic niche.2011
- Author(s)
  Suda T, Takubo K
- Organizer
  Gordon Research Conferences on Stem Cells & Cancer
- Place of Presentation
  Ventura, U.S.A.
- Data Source
  KAKENHI-PLANNED-22130004
[Presentation] 骨髄腫ニッチの解析2011
- Author(s)
  田久保圭誉
- Organizer
  第14回癌と骨病変研究会
- Place of Presentation
  千代田放送会館(東京)
- Year and Date
  2011-11-18
- Data Source
  KAKENHI-PUBLICLY-23118527
[Presentation] Glycolytic Energy Metabolism by Pdk Maintains Quiescence of Hematopoietic Stem Cells2011
- Author(s)
  田久保圭誉
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋国際会議場(名古屋)
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PUBLICLY-23118527
[Presentation] Pdkを介した代謝プログラムによる造血幹細胞維持とその操作2011
- Author(s)
  田久保圭誉
- Organizer
  新学術領域「細胞運命制御」若手の会
- Place of Presentation
  軽井沢プリンスホテル(軽井沢)
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-23689049
[Presentation] Anaerobic energy metabolism regulates hematopoietic stem cell quiescence2011
- Author(s)
  Keiyo Takubo
- Organizer
  3rd Else Kroner--Fresenius Symposium on Molecular Mechanisms of Adult Stem Cell Aging
- Place of Presentation
  Reisensburg Castle(ドイツギュンツブルグ)
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PUBLICLY-23118527
[Presentation] A protective metabolic program in hematopoietic stem cells2011
- Author(s)
  Keiyo Takubo
- Organizer
  第9回幹細胞シンポジウム
- Place of Presentation
  泉ガーデンギャラリー(東京)
- Year and Date
  2011-05-14
- Data Source
  KAKENHI-PUBLICLY-23118527
[Presentation] 低酸素応答系による造血幹細胞の代謝プログラム制御機構2011
- Author(s)
  田久保圭誉
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PUBLICLY-23118527
[Presentation] 造血幹細胞の新たな幹細胞性としてのエネルギー代謝制御機構2011
- Author(s)
  田久保圭誉
- Organizer
  国立感染症研究所血液・安全性研究部セミナー
- Place of Presentation
  国立感染症研究所(東京)
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PUBLICLY-23118527
[Presentation] Anaerobic Metabolism Maintains Quiescence of Hematopoietic Stem Cell USA-Japan Cooperative Cancer Research Workshop2011
- Author(s)
  Takubo K.
- Place of Presentation
  Hayama, Japan
- Year and Date
  2011-02-25
- Data Source
  KAKENHI-PROJECT-21790925
[Presentation] Pdk-mediated Modulation of Cell Cycle of Long-Term Hematopoietic Stem Cells2011
- Author(s)
  田久保圭誉
- Organizer
  第8回がんとハイポキシア研究会
- Place of Presentation
  北海道大学医学部(札幌)
- Year and Date
  2011-01-29
- Data Source
  KAKENHI-PUBLICLY-21028018
[Presentation] 低酸素応答系による造血幹細胞の代謝プログラム制御機構2011
- Author(s)
  田久保圭誉
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立東都国際会館(京都)
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-23689049
[Presentation] 骨髄腫ニッチの解析2011
- Author(s)
  田久保圭誉
- Organizer
  第14回癌と骨病変研究会
- Place of Presentation
  千代田放送会館(東京)
- Year and Date
  2011-11-18
- Data Source
  KAKENHI-PROJECT-23689049
[Presentation] A protective metabolic program in hematopoietic stem cells2011
- Author(s)
  Keiyo Takubo
- Organizer
  第9回幹細胞シンポジウム
- Place of Presentation
  泉ガーデンギャラリー(東京)
- Year and Date
  2011-05-14
- Data Source
  KAKENHI-PROJECT-23689049
[Presentation] Regulation of "stemness" by Hypoxic Bone Marrow Microenvironment2010
- Author(s)
  Takubo K.
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21790925
[Presentation] VHL/HIF-1α制御系による造血幹細胞の恒常性維持機構2010
- Author(s)
  田久保圭誉
- Organizer
  CREST研究領域「代謝調節機構解析に基づく細胞機能制御基盤技術」第3回公開シンポジウム
- Place of Presentation
  東京大学弥生講堂(東京)
- Year and Date
  2010-10-21
- Data Source
  KAKENHI-PUBLICLY-21028018
[Presentation] Suppressor Effect of Novel Antitumor Drug, Bendamustine on Multiple Myeloma in Humanized Mouse Model2010
- Author(s)
  Keiyo Takubo
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-21790925
[Presentation] Suppressor Effect of Novel Antitumor Drug, Bendamustine on Multiple Myeloma in Humanized Mouse Model2010
- Author(s)
  Keiyo Takubo
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PUBLICLY-21028018
[Presentation] 低酸素ニッチにおける幹細胞のエネルギー代謝2010
- Author(s)
  田久保圭誉
- Organizer
  若手放射線生物学研究会新春勉強会
- Place of Presentation
  千葉
- Year and Date
  2010-01-30
- Data Source
  KAKENHI-PROJECT-21790925
[Presentation] Purification analysis of testicular germ line and somatic subpopulations.2010
- Author(s)
  Takubo K, Nagamatsu G, Iriuchishima H, Ishikawa C, Suda T.
- Organizer
  International Symposium on Epigenome Network, Development and Reprogramming of Germ Cells
- Place of Presentation
  福岡
- Year and Date
  2010-11-22
- Data Source
  KAKENHI-PROJECT-21790925
[Presentation] 低酸素応答システムによる幹細胞性と代謝恒常性の維持2010
- Author(s)
  田久保圭誉
- Organizer
  第5回生体恒常性とストレスセミナー
- Place of Presentation
  山口大学医学部(宇部)
- Year and Date
  2010-11-24
- Data Source
  KAKENHI-PUBLICLY-21028018
[Presentation] Purification analysis of testicular germ line and somatic subpopulations.2010
- Author(s)
  Keiyo Takubo
- Organizer
  International Symposium on Epigenome Network, Development and Reprogramming of Germ Cells
- Place of Presentation
  九州大学医学部百年講堂(福岡)
- Year and Date
  2010-11-22
- Data Source
  KAKENHI-PUBLICLY-21028018
[Presentation] Regulation of "stemness" by Hypoxic Bone Marrow Microenvironment2010
- Author(s)
  Keiyo Takubo
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21790925
[Presentation] Suppressor Effect of Novel Antitumor Drug, Bendamustine on Multiple Myeloma in Humanized Mouse Model2010
- Author(s)
  Takubo K, Iriuchishima H, Yamada W, Miyakawa Y, Miyamoto T, Suda T.
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-21790925
[Presentation] Purification analysis of testicular germ line and somatic subpopulations.2010
- Author(s)
  Keiyo Takubo
- Organizer
  International Symposium on Epigenome Network, Development and Reprogramming of Germ Cells
- Place of Presentation
  九州大学医学部百年講堂(福岡)
- Year and Date
  2010-11-22
- Data Source
  KAKENHI-PROJECT-21790925
[Presentation] VHL/HIF-1・制御系による造血幹細胞の恒常性維持機構「代謝調節機構解析に基づく細胞機能制御基盤技術」2010
- Author(s)
  田久保圭誉, 須田年生
- Organizer
  第3回公開シンポジウム
- Place of Presentation
  東京
- Year and Date
  2010-10-21
- Data Source
  KAKENHI-PROJECT-21790925
[Presentation] 低酸素応答系による造血幹細胞の維持2010
- Author(s)
  田久保圭誉
- Organizer
  第10回血液フォーラム21
- Place of Presentation
  東京
- Year and Date
  2010-03-05
- Data Source
  KAKENHI-PUBLICLY-21028018
[Presentation] VHL/HIF-1α制御系による造血幹細胞の恒常性維持機構2010
- Author(s)
  田久保圭誉
- Organizer
  CREST研究領域「代謝調節機構解析に基づく細胞機能制御基盤技術」第3回公開シンポジウム
- Place of Presentation
  東京大学弥生講堂(東京)
- Year and Date
  2010-10-21
- Data Source
  KAKENHI-PROJECT-21790925
[Presentation] Regulation of "stemness" by Hypoxic Bone Marrow Microenvironment2010
- Author(s)
  Keiyo Takubo
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PUBLICLY-21028018
[Presentation] 低酸素応答系による造血幹細胞の維持2010
- Author(s)
  田久保圭誉
- Organizer
  第10回血液フォーラム21
- Place of Presentation
  東京
- Year and Date
  2010-03-05
- Data Source
  KAKENHI-PROJECT-21790925
[Presentation] 低酸素応答シグナルによる造血幹細胞の維持2010
- Author(s)
  田久保圭誉
- Organizer
  第31回日本炎症・再生医学会ミニシンポジウム5「幹細胞と老化、ストレス」
- Place of Presentation
  東京・新宿
- Year and Date
  2010-08-06
- Data Source
  KAKENHI-PROJECT-21790925
[Presentation] 低酸素ニッチにおける幹細胞のエネルギー代謝2010
- Author(s)
  田久保圭誉
- Organizer
  若手放射線生物学研究会新春勉強会
- Place of Presentation
  千葉
- Year and Date
  2010-01-30
- Data Source
  KAKENHI-PUBLICLY-21028018
[Presentation] 低酸素応答シグナルによる造血幹細胞の維持2010
- Author(s)
  田久保圭誉
- Organizer
  第31回日本炎症・再生医学会
- Place of Presentation
  京王プラザホテル(東京)
- Year and Date
  2010-08-06
- Data Source
  KAKENHI-PROJECT-21790925
[Presentation] 低酸素応答シグナルによる造血幹細胞の維持2010
- Author(s)
  田久保圭誉
- Organizer
  第31回日本炎症・再生医学会
- Place of Presentation
  京王プラザホテル(東京)
- Year and Date
  2010-08-06
- Data Source
  KAKENHI-PUBLICLY-21028018
[Presentation] 低酸素応答システムによる幹細胞性と代謝恒常性の維持2010
- Author(s)
  田久保圭誉
- Organizer
  第5回生体恒常性とストレスセミナー
- Place of Presentation
  山口大学医学部(宇部)
- Year and Date
  2010-11-24
- Data Source
  KAKENHI-PROJECT-21790925
[Presentation] A Protective Program for Hematopoietic Stem Cells by Anaerobic Metabolism2009
- Author(s)
  Keiyo Takubo
- Organizer
  第71回日本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21790925
[Presentation] マウス未分化型精原細胞特異的遺伝子群のプロモーター解析「生殖系列の世代サイクルとエピゲノムネットワーク」2009
- Author(s)
  田久保圭誉, 須田年生
- Organizer
  第2回公開シンポジウム
- Place of Presentation
  品川・コクヨホール
- Data Source
  KAKENHI-PROJECT-21790925
[Presentation] A Protective Program for Hematopoietic Stem Cells by Anaerobic Metabolism2009
- Author(s)
  Takubo K.
- Organizer
  第71回日本血液学会学術集会シンポジウム5"Hematopoietic Stem Cell Niche"
- Place of Presentation
  京都
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21790925
[Presentation] A Protective Program for Hematopoietic Stem Cells by Anaerobic Metabolism2009
- Author(s)
  Keiyo Takubo
- Organizer
  第71回日本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PUBLICLY-21028018
[Presentation] Regulation of Leukemia Initiating Cells in the Hypoxic CML Niche
- Author(s)
  Keiyo Takubo
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23689049
[Presentation] ニッチによる造血幹細胞の動態制御
- Author(s)
  田久保圭誉
- Organizer
  東京大学分子細胞生物学研究所セミナー
- Place of Presentation
  東京大学分子細胞生物学研究所
- Invited
- Data Source
  KAKENHI-PUBLICLY-25118724
[Presentation] Regulation of Leukemia Initiating Cells in the Hypoxic CML Niche
- Author(s)
  Keiyo Takubo
- Organizer
  第10回幹細胞シンポジウム
- Place of Presentation
  淡路
- Data Source
  KAKENHI-PROJECT-23689049
[Presentation] PROLYL AND ASPARAGINYL HYDROXYLATION IN HYPOXIA-INDUCIBLE FACTOR PLAYS A CRITICAL ROLE IN HEMATOPOIETIC STEM CELL MAINTENANCE
- Author(s)
  Takubo K
- Organizer
  ISSCR 11th Annual Meeting
- Place of Presentation
  Boston
- Invited
- Data Source
  KAKENHI-PUBLICLY-25118724
[Presentation] PROLYL AND ASPARAGINYL HYDROXYLATION IN HYPOXIA-INDUCIBLE FACTOR PLAYS A CRITICAL ROLE IN HEMATOPOIETIC STEM CELL MAINTENANCE
- Author(s)
  Takubo K
- Organizer
  ISSCR 11th Annual Meeting
- Place of Presentation
  Boston
- Invited
- Data Source
  KAKENHI-PROJECT-23689049
[Presentation] ニッチによる造血幹細胞の動態制御
- Author(s)
  田久保圭誉
- Organizer
  東京大学分子細胞生物学研究所セミナー
- Place of Presentation
  東京大学分子細胞生物学研究所
- Invited
- Data Source
  KAKENHI-PROJECT-23689049
[Presentation] ニッチによる造血幹細胞の恒常性制御機構と病態における変容
- Author(s)
  田久保圭誉
- Organizer
  北海道大学大学院歯学研究セミナー
- Place of Presentation
  北海道大学大学院歯学研究科
- Invited
- Data Source
  KAKENHI-PROJECT-23689049
[Presentation] ニッチによる造血幹細胞の恒常性制御機構と病態における変容
- Author(s)
  田久保圭誉
- Organizer
  北海道大学大学院歯学研究セミナー
- Place of Presentation
  北海道大学大学院歯学研究科
- Invited
- Data Source
  KAKENHI-PUBLICLY-25118724
[]

1. SUDA Toshio (60118453)

# of Collaborated Projects: 6 results

# of Collaborated Products: 15 results
2. NAGAMATSU Go (70453545)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
3. Iwama Atsushi (70244126)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 真田昌 (20529044)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. 波江野洋 (70706754)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. Nishimura Emi

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. Sato Toshiro

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. Minamino Toru

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. Nabeshima Yoichi

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. KOBAYASHI Hiroshi

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
11. MORIKAWA Takayuki

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
12. KARIGANE Daiki

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. TAMAKI Shinpei

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. HARAGUCHI Miho

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. ARAI Fumio (90365403)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
16. MIYAMOTO Takeshi (70383768)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
17. MATSUOKA Sahoko (20317340)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
18. YOSHIHARA Hiroki (90348706)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. IKUSHIMA Yoshiko (00571366)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. HOSOKAWA Kentaro (90569584)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. GOITSUKA RYO (50301552)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. Hase Koji (20359714)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 大谷直子 (50275195)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 馬場理也 (10347304)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
25. 石津綾子 (10548548)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 梅本晃正 (50620225)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 坂本比呂志 (00347014)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 河村由紀 (10392391)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 松田幹 (20144131)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. Hara Eiji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. Ho Anthony

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. SHIMADA Midori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. TSUGAWA Hitoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. UEDA Takeshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
35. YAMASHITA Masayuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. GODA Nobuhito

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. FUKUSHIMA Satoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 三河拓己

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 本田善一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
40. 本田浩章

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
41. 白髭克彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 加部泰明

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
43. 松井啓隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 稲葉俊哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
45. 井上克枝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
46. 仁田英里子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
47. 樗木俊聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
48. 金井昭教

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
49. 世良康如

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
50. 望月牧子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
51. 尹浩信

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takubo Keiyo 田久保 圭誉

TAKUBO Keiyo 田久保 圭誉

Research Projects

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動的な酸素シグナルによる非典型的細胞運命決定機構の解明Principal Investigator

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侵害受容神経による造血幹細胞の骨髄間移動制御の解明と応用Principal Investigator

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Establishment of real-time measurement technique for ATP concentration and amount in single hematopoietic stem cellsPrincipal Investigator

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Establishment of imaging technique for spatiotemporal dynamics of hematopoietic stem cells in bone marrowPrincipal Investigator

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Spatio-temporal analysis of hematopoietic stem cell dynamics through visualization and manipulation of bone marrow oxygen environmentPrincipal Investigator

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Measuring shape and movement of hematopoietic stem cellsPrincipal Investigator

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Composition and function of metabolites as hematopoietic stem cell niche factorsPrincipal Investigator

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Identification and characterization of biological targets of chemical expander for hematopoietic stem cellsPrincipal Investigator

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Impact of hydroxylation signals on homeostatic regulation of hematopoiesisPrincipal Investigator

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Aging and anti-aging mechanisms in niche-hematopoietic stem cell interactionPrincipal Investigator

Takubo Keiyo 田久保圭誉

TAKUBO Keiyo 田久保圭誉