Osawa Tsuyoshi 大澤毅

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OSAWA Tsuyoshi 大澤毅

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Researcher Number	50567592
Other IDs
Affiliation (Current)	2025: 東京大学, 先端科学技術研究センター, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2025: 東京大学, 先端科学技術研究センター, 准教授 2017 – 2022: 東京大学, 先端科学技術研究センター, 特任准教授 2011 – 2016: 東京大学, 先端科学技術研究センター, 特任助教
Review Section/Research Field	Principal Investigator Medium-sized Section 50:Oncology and related fields / Biological Sciences / Tumor biology / Complex systems / Transformative Research Areas, Section (III) / Basic Section 50010:Tumor biology-related / Tumor biology Except Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / Medium-sized Section 49:Pathology, infection/immunology, and related fields / Basic Section 56040:Obstetrics and gynecology-related / Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords	Principal Investigator がん微小環境 / がん代謝 / オミクス統合解析 / 癌 / アミノ酸 / 代謝 / ストレス / 転写・代謝制御 / がん / 低pH … More / 腫瘍微小環境 / 低栄養 / 低酸素 / 代謝アダプテーション / 細胞文脈 / 栄養センサー / オルガネラ / 細胞間相互作用 / 代謝フィードバック / アミノ酸代謝 / アミノ酸センサー / アミノ酸欠乏 / 転写制御 / ゲノム / がん幹細胞 / 脂質 / システム生物 / 転写 / ヒストン修飾 / 細胞・組織 / ヒストン / エピジェネティクス / 組織・細胞 … More Except Principal Investigator オンコメタボライト / 神経芽腫 / 尿中代謝物 / 代謝リプログラミング / 中心代謝 / キャピラリー電気泳動質量分析法 / バイオマーカー / 液体クロマトグラフィー質量分析法 / 腎芽腫 / MYC遺伝子 / HMGB1 / TCTP / 腫瘍免疫 / DAMPs / ゲノム / 代謝 / 腸内細菌 / 炎症食 / CE-MS / LC-MS / メタボロミクス / 横紋筋肉腫 / 尿中バイオマーカー / 液体クロマト質量分析法 / Wilms腫瘍 / 尿代謝物 / メタボローム解析 / 小児希少がん Less

pH関連代謝物のカタログ化および計測技術開発Principal Investigator
- Principal Investigator
  
  大澤毅
- Project Period (FY)
  2025 – 2029
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  The University of Tokyo
新規神経芽腫マーカー（CTN/VLA）の有効性（診断率・悪性度予測）検証と病態解明
- Principal Investigator
  
  檜顕成
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Nagoya University
婦人科がん患者のQOLや治療成績に関わる食事と腸内細菌叢・代謝物の探索的研究
- Principal Investigator
  
  山口建
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Kyoto University
自己由来分子による炎症・免疫応答系の調節機構の解明と関連病態制御の基盤構築
- Principal Investigator
  
  谷口維紹
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  The University of Tokyo
Exploring cancer specific organelle nutrient sensorsPrincipal Investigator
- Principal Investigator
  
  大澤毅
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  The University of Tokyo
Improvement and Validation of a Discriminant Model for Amplification of the Neuroblastoma MYC Gene by Tyrosine Metabolite Markers
- Principal Investigator
  
  牧田智
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Nagoya University
腎芽腫メタボローム解析（尿/組織）による診断マーカーとオンコメタボライト探索
- Principal Investigator
  
  岡本眞宗
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Toho University
横紋筋肉腫メタボローム解析（尿/組織）による診断マーカーとオンコメタボライト探索
- Principal Investigator
  
  住田亙
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Nagoya University
腎芽腫患児の代謝物網羅解析によるバイオマーカーの探索と創薬への挑戦
- Principal Investigator
  
  田中裕次郎
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Saitama Medical University
Elucidation of metabolointeractome in tumor microenvironmentsPrincipal Investigator
- Principal Investigator
  
  Osawa Tsuyoshi
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  The University of Tokyo
がん微小環境における代謝適応フィードバックシステムの解明Principal Investigator
- Principal Investigator
  
  大澤毅
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Elucidation of amino acid adaptive sensor in cancer cellsPrincipal Investigator
- Principal Investigator
  
  Osawa Tsuyoshi
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  The University of Tokyo
Tolerance of cancer cells against amino acids deprivation in tumor microenvironmentsPrincipal Investigator
- Principal Investigator
  
  Tsuyoshi Osawa
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  The University of Tokyo
Elucidation of metabolic adaptation in tumor microenvironmentPrincipal Investigator
- Principal Investigator
  
  大澤毅
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  The University of Tokyo
Conquering cancer through neo-dimensional systems understandingPrincipal Investigator
- Principal Investigator
  
  大澤毅
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  The University of Tokyo
Conquering cancer through understanding of tumor microenvironmentPrincipal Investigator
- Principal Investigator
  
  大澤毅
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  The University of Tokyo
Understanding mechanism of acidic pH induced tumor progressionPrincipal Investigator
- Principal Investigator
  
  Osawa Tsuyoshi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor biology
- Research Institution
  The University of Tokyo
腫瘍微小環境における転写環境とエネルギー代謝の解明Principal Investigator
- Principal Investigator
  
  大澤毅
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Understanding the mechanism of CSCs maintenance in tumor microenvironmentPrincipal Investigator
- Principal Investigator
  
  Osawa Tsuyoshi
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Tumor biology
- Research Institution
  The University of Tokyo
腫瘍微小環境のシステム的統合理解に基づく治療法の開発Principal Investigator
- Principal Investigator
  
  大澤毅
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  The University of Tokyo
低酸素・低栄養の腫瘍微小環境における転写と代謝のクロストークPrincipal Investigator
- Principal Investigator
  
  大澤毅
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Targeting cancer cells resistant to hypoxia and nutrient starvation to improve anti-cancer therapyPrincipal Investigator
- Principal Investigator
  
  OSAWA Tsuyoshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  The University of Tokyo

[Book] マルチオミクス研究のすすめ ~ マルチオミクスデータ駆動時代の疾患研究2023
- Author(s)
  大澤　毅
- Total Pages
  222
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-23K18234
[Book] 疾患原因遺伝子・タンパク質の解析技術と創薬/診断技術への応用2022
- Author(s)
  大澤毅ら
- Total Pages
  530
- Publisher
  技術情報協会
- ISBN
  9784861048777
- Data Source
  KAKENHI-PUBLICLY-20H04834
[Book] Precision Medicine 哺乳類胚の休眠ダイナミクス2019
- Author(s)
  大澤毅　他
- Total Pages
  84
- Publisher
  北隆館
- ISBN
- Data Source
  KAKENHI-PUBLICLY-18H04797
[Book] 医学のあゆみ　多階層オミクス統合解析-オミクス解析2019
- Author(s)
  望月直樹　大澤毅　他
- Total Pages
  120
- Publisher
  医歯薬出版株式会社
- ISBN
- Data Source
  KAKENHI-PUBLICLY-18H04797
[Book] Precision　哺乳類胚の休眠ダイナミクス2019
- Author(s)
  大澤毅　他
- Total Pages
  84
- Publisher
  北隆館
- ISBN
- Data Source
  KAKENHI-PUBLICLY-18H04897
[Book] 医学のあゆみ　多階層オミクス統合解析-オミクス解析2019
- Author(s)
  望月直樹　大澤毅　他
- Total Pages
  120
- Publisher
  医歯薬出版株式会社
- ISBN
- Data Source
  KAKENHI-PUBLICLY-18H04897
[Book] 酸性環境における腫瘍の悪性化機構, 生化学2018
- Author(s)
  近藤彩乃, 大澤毅
- Publisher
  国際文献社
- Data Source
  KAKENHI-PUBLICLY-18H04797
[Book] 酸性環境における腫瘍の悪性化機構, 生化学2018
- Author(s)
  近藤彩乃, 大澤毅
- Publisher
  国際文献社
- Data Source
  KAKENHI-PUBLICLY-18H04897
[Book] 血管のバイオロジーオミクスが加速させる血管研究, 細胞2018
- Author(s)
  大澤毅
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PUBLICLY-18H04797
[Book] 血管のバイオロジーオミクスが加速させる血管研究, 細胞,2018
- Author(s)
  大澤毅
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-26710005
[Book] 酸性環境における腫瘍の悪性化機構, 生化学2018
- Author(s)
  近藤彩乃, 大澤毅
- Publisher
  国際文献社
- Data Source
  KAKENHI-PROJECT-26710005
[Book] 血管のバイオロジーオミクスが加速させる血管研究, 細胞2018
- Author(s)
  大澤毅
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PUBLICLY-18H04897
[Book] 「酢酸代謝」、実験医学がん代謝ワールブルグを超えて全容解明に挑む2017
- Author(s)
  大澤　毅
- Total Pages
  5
- Publisher
  羊土社
- ISBN
- Data Source
  KAKENHI-PROJECT-16K14605
[Book] 「酢酸代謝」、実験医学がん代謝ワールブルグを超えて全容解明に挑む2017
- Author(s)
  大澤　毅
- Total Pages
  5
- Publisher
  羊土社
- ISBN
- Data Source
  KAKENHI-PROJECT-26710005
[Book] 「酢酸代謝」、実験医学がん代謝ワールブルグを超えて全容解明に挑む2017
- Author(s)
  大澤　毅
- Total Pages
  5
- Publisher
  羊土社
- ISBN
- Data Source
  KAKENHI-PUBLICLY-16H01567
[Book] 遺伝子制御の新たな主役栄養シグナル2017
- Author(s)
  大澤毅
- Total Pages
  6
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-16K14605
[Book] 実験医学　遺伝子制御の新たな主役栄養シグナル2017
- Author(s)
  大澤毅
- Total Pages
  6
- Publisher
  羊土社
- Data Source
  KAKENHI-PUBLICLY-16H01567
[Book] 実験医学　遺伝子制御の新たな主役栄養シグナル2017
- Author(s)
  大澤毅
- Total Pages
  6
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-26710005
[Journal Article] Convergent Genomic Diversity and Novel BCAA Metabolism in Intrahepatic Cholangiocarcinoma2023
- Author(s)
  Kitagawa A, Osawa T, Noda M, Kobayashi Y, et al. and Mimori K.
- Journal Title
  
  Br. J. Cancer
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K19399
[Journal Article] Cancer Metabolism within the Tumor Microenvironments2023
- Author(s)
  Aki S, Nakahara R, Maeda K, Osawa T
- Journal Title
  
  BBA
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03496
[Journal Article] Tumor cell derived spermidine is an oncometabolite that suppresses TCR clustering for intratumoral CD8+ T cell activation2023
- Author(s)
  Hibino S, Eto S, Hangai S, Endo K, Ashitani S, Sugaya M, Osawa T, Soga T, Taniguchi T and Yanai H
- Journal Title
  
  PNAS
  
  Volume: 120 (24) Issue: 24
- DOI
  10.1073/pnas.2305245120
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18234, KAKENHI-PUBLICLY-23H04772, KAKENHI-ORGANIZER-23H04939, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-20H00504, KAKENHI-PROJECT-23K24149
[Journal Article] Metabolic adaptations of cancer in extreme tumor microenvironments2023
- Author(s)
  Ryuichi Nakahara、Keisuke Maeda、Sho Aki、Tsuyoshi Osawa
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 4 Pages: 1200-1207
- DOI
  10.1111/cas.15722
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-19H03496, KAKENHI-PROJECT-22KJ0927, KAKENHI-PROJECT-20K07260, KAKENHI-PROJECT-21K19399, KAKENHI-PROJECT-23K18234, KAKENHI-PROJECT-23KJ0581
[Journal Article] Convergent Genomic Diversity and Novel BCAA Metabolism in Intrahepatic Cholangiocarcinoma2023
- Author(s)
  Kitagawa A, Osawa T, Noda M, Kobayashi Y, et al. and Mimori K.
- Journal Title
  
  Br. J. Cancer
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03496
[Journal Article] Cancer metabolism within tumor microenvironments2023
- Author(s)
  Aki Sho、Nakahara Ryuichi、Maeda Keisuke、Osawa Tsuyoshi
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - General Subjects
  
  Volume: 1867 Issue: 5 Pages: 130330-130330
- DOI
  10.1016/j.bbagen.2023.130330
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07260, KAKENHI-PROJECT-23K18234, KAKENHI-PROJECT-23KJ0581, KAKENHI-PROJECT-22KJ0927, KAKENHI-PROJECT-22H04925
[Journal Article] Convergent genomic diversity and novel BCAA metabolism in intrahepatic cholangiocarcinoma2023
- Author(s)
  Kitagawa A, Osawa T,Noda M,Kobayashi Y, Aki S,Nakano Y,Saito T,Shimizu D,Komatsu H,Sugaya M,Takahashi J,...Mimori K.
- Journal Title
  
  Br J Cancer
  
  Volume: - Issue: 12 Pages: 22068-22068
- DOI
  10.1038/s41416-023-02256-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08826, KAKENHI-PROJECT-20H04281, KAKENHI-PROJECT-20K07260, KAKENHI-PROJECT-20K21832, KAKENHI-PUBLICLY-22H04839, KAKENHI-PROJECT-23K18234, KAKENHI-PROJECT-22K07774, KAKENHI-PROJECT-22K09006, KAKENHI-PROJECT-21K08745, KAKENHI-PLANNED-23H04938, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-23K24164
[Journal Article] NRF3 activates mTORC1 arginine-dependently for cancer cell viability2023
- Author(s)
  Hirose Shuuhei、Waku Tsuyoshi、Tani Misato、Masuda Haruka、Endo Keiko、Ashitani Sanae、Aketa Iori、Kitano Hina、Nakada Sota、Wada Ayaka、Hatanaka Atsushi、Osawa Tsuyoshi、Soga Tomoyoshi、Kobayashi Akira
- Journal Title
  
  iScience
  
  Volume: 26 Issue: 2 Pages: 106045-106045
- DOI
  10.1016/j.isci.2023.106045
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07219, KAKENHI-PROJECT-19H03496, KAKENHI-PROJECT-20H04135, KAKENHI-PROJECT-20J20194, KAKENHI-PROJECT-21K19399, KAKENHI-PROJECT-21K19743, KAKENHI-PUBLICLY-22H04659, KAKENHI-PROJECT-23K18234, KAKENHI-PROJECT-22H04925
[Journal Article] Hypoxia activates SREBP2 through Golgi disassembly in bone marrow-derived monocytes for enhanced tumor growth2023
- Author(s)
  Nakahara R, Aki S, Sugaya M, Hirose H, Kato M, Maeda K, Sakamoto DM, Kojima Y, Nishida M, Ando R, Muramatsu M, Pan M, Tsuchida R, Matsumura Y, Yanai H, Takano H, Yao R, Sando S, Shibuya M, Sakai J, Kodama T, Kidoya H, Shimamura T, Osawa T.
- Journal Title
  
  The EMBO Journal
  
  Volume: 42 Issue: 22 Pages: 15252-15252
- DOI
  10.15252/embj.2023114032
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K18411, KAKENHI-PROJECT-23K18234, KAKENHI-PROJECT-23KJ0581, KAKENHI-PROJECT-22KJ0927, KAKENHI-PUBLICLY-23H04772, KAKENHI-PLANNED-23H04938, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-21H04826, KAKENHI-PROJECT-23K24149
[Journal Article] Acidic Extracellular pH Drives Accumulation of N1-Acetylspermidine and Recruitment of Pro-Tumor Neutrophils2023
- Author(s)
  Kato M, Maeda K, Nakahara R, Hirose H, Kondo A, Aki S, Sugaya M, Hibino S, Nishida M, Hasegawa M, Morita H, Ando R, Tsuchida R, Yoshida M, Kodama T, Yanai H, Shimamura T and Osawa T
- Journal Title
  
  PNAS Nexus
  
  Volume: 10 Issue: 10 Pages: 1093-1093
- DOI
  10.1093/pnasnexus/pgad306
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18234, KAKENHI-PROJECT-23KJ0581, KAKENHI-PROJECT-22KJ0927, KAKENHI-PUBLICLY-23H04772, KAKENHI-PLANNED-23H04882, KAKENHI-PLANNED-23H04938, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-23H05473, KAKENHI-PROJECT-23K24149
[Journal Article] Cancer Metabolism within the Tumor Microenvironments2023
- Author(s)
  Aki S, Nakahara R, Maeda K, Osawa T
- Journal Title
  
  BBA
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K19399
[Journal Article] Antibody mimetic drug conjugate manufactured by high-yield Escherichia coli expression and non-covalent binding system2022
- Author(s)
  Yamatsugu Kenzo、Katoh Hiroto、Yamashita Takefumi、Takahashi Kazuki、Aki Sho、Tatsumi Toshifumi、Kaneko Yudai、Kawamura Takeshi、Miura Mai、Ishii Masazumi、Ohkubo Kei、Osawa Tsuyoshi、Kodama Tatsuhiko、Ishikawa Shumpei、Kanai Motomu、Sugiyama Akira
- Journal Title
  
  Protein Expression and Purification
  
  Volume: 192 Pages: 106043-106043
- DOI
  10.1016/j.pep.2021.106043
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03510, KAKENHI-PROJECT-21H02779, KAKENHI-PROJECT-19H03496, KAKENHI-PROJECT-20H02779, KAKENHI-PROJECT-20K07260, KAKENHI-PROJECT-21K19399, KAKENHI-PUBLICLY-20H04819
[Journal Article] Selective PPARα Modulator Pemafibrate and Sodium-Glucose Cotransporter 2 Inhibitor Tofogliflozin Combination Treatment Improved Histopathology in Experimental Mice Model of Non-Alcoholic Steatohepatitis2022
- Author(s)
  Murakami K, Sasaki Y, Asahiyama M, Yano W, Takizawa T, Kamiya W, Matsumura Y, Anai M, Osawa T, Fruchart JC, Fruchart-Najib J, Aburatani H, Sakai J, Kodama T, Tanaka T.
- Journal Title
  
  Cells
  
  Volume: 11 Issue: 4 Pages: 720-720
- DOI
  10.3390/cells11040720
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06608, KAKENHI-PROJECT-16H06390, KAKENHI-PUBLICLY-20H04835, KAKENHI-PROJECT-20K21747, KAKENHI-PROJECT-19H03496, KAKENHI-PROJECT-21K19399, KAKENHI-PROJECT-21H04826
[Journal Article] Metagenomic identification of microbial signatures predicting pancreatic cancer from a multinational study2022
- Author(s)
  Nagata N, Nishijima S, Kojima Y, Hisada Y, Imbe K, Miyoshi-Akiyama T, Suda W, Kimura M, Aoki R, Sekine K, Ohsugi M, Miki K, Osawa T, Ueki T, Oka S, Mizokami M, Kartal E, Schmidt TSB, Molina-Montes E, Estudillo L, Malats N, Trebicka J, Kersting S, Langheinrich M, Bork P, Uemura N, Itoi T, and Kawai T
- Journal Title
  
  Gastroenterology
  
  Volume: 163 Issue: 1 Pages: 222-238
- DOI
  10.1053/j.gastro.2022.03.054
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03496, KAKENHI-PROJECT-21K19399
[Journal Article] Pathological complete remission of relapsed tumor by photo‐activating antibody-mimetic drug conjugate treatment2022
- Author(s)
  Kaneko Yudai、Yamatsugu Kenzo、Yamashita Takefumi、Takahashi Kazuki、Tanaka Toshiya、Aki Sho、Tatsumi Toshifumi、Kawamura Takeshi、Miura Mai、Ishii Masazumi、Ohkubo Kei、Osawa Tsuyoshi、Kodama Tatsuhiko、Ishikawa Shumpei、Tsukagoshi Masanobu、Chansler Michael、Sugiyama Akira、Kanai Motomu、Katoh Hiroto
- Journal Title
  
  Cancer Science
  
  Volume: 113 Issue: 12 Pages: 4350-4362
- DOI
  10.1111/cas.15565
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05024, KAKENHI-PROJECT-19H01032, KAKENHI-PROJECT-19H03496, KAKENHI-PROJECT-20H02779, KAKENHI-PROJECT-21H02779, KAKENHI-PROJECT-20K07260, KAKENHI-PROJECT-21K19399, KAKENHI-PUBLICLY-20H04819, KAKENHI-ORGANIZER-22H05017
[Journal Article] Glutamine deficiency in solid tumor cells confers resistance to ribosomal RNA synthesis inhibitors2022
- Author(s)
  Melvin Pan、Christiane Zorbas、Maki Sugaya、Kensuke Ishiguro、Miki Kato、Miyuki Nishida、Hai-Feng Zhang、Marco M. Candeias、Akimitsu Okamoto、Takamasa Ishikawa、Tomoyoshi Soga、Hiroyuki Aburatani、Juro Sakai、Yoshihiro Matsumura、Tsutomu Suzuki、Christopher G. Proud、Denis L. J. Lafontaine、Tsuyoshi Osawa
- Journal Title
  
  Nature Communications
  
  Volume: 13(1) Issue: 1 Pages: 3706-3706
- DOI
  10.1038/s41467-022-31418-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-19H01031, KAKENHI-PROJECT-19H03496, KAKENHI-PROJECT-21K19040, KAKENHI-PROJECT-21K19399, KAKENHI-PROJECT-21H04826, KAKENHI-PLANNED-18H05504, KAKENHI-PROJECT-18H05272
[Journal Article] Loss of Down syndrome critical region-1 leads to cholesterol metabolic dysfunction that exaggerates hypercholesterolemia in ApoE-null background2021
- Author(s)
  Muramatsu M#, Osawa T#, Miyamura Y, Nakagawa S, Tanaka T, Kodama T, Aburatani H, Sakai J, Ryeom S, Minami T
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: In press
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22553
[Journal Article] Fluoxuridine Oligomers Activated under Hypoxic Environment2021
- Author(s)
  Morihiro K, Ishinabe T, Takatsu M, Osumi H, Osawa T, Okamoto A
- Journal Title
  
  J. Am. Chem. Soc
  
  Volume: 143 Pages: 3340-2247
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22553
[Journal Article] Metabolic flexibility via mitochondrial BCAA carrier SLC25A44 is required for optimal fever2021
- Author(s)
  Yoneshiro T, Kataoka N, Walejko JM, Ikeda K, Brown Z, Yoneshiro M, Crown SB, Osawa T, Sakai J, McGarrah RW, White PJ,Nakamura K, and Kajimura S
- Journal Title
  
  eLife
  
  Volume: In press
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22553
[Journal Article] TET1 upregulation drives cancer cell growth by aberrant enhancer hydroxymethylation of HMGA2 in hepatocellular carcinoma2021
- Author(s)
  Shirai K, Nagae G, Seki M, Kudo Y, Kamio A, Hayashi A, Okabe A, Ota S, Tsutsumi S, Fujita T, Yamamoto S, Nakaki R, Kanki Y, Osawa T, Midorikawa Y, Tateishi K, Ichinose M, Aburatani H
- Journal Title
  
  Cancer Science
  
  Volume: In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22553
[Journal Article] Gene Expression Profiles Induced by a Novel Selective Peroxisome Proliferator-Activated Receptor α Modulator (SPPARMα) Pemafibrate2019
- Author(s)
  Sasaki Y, Raza-Iqbal S, Tanaka T, Murakami K, Anai M, Osawa T, Matsumura Y, Sakai J, Kodama T
- Journal Title
  
  Int J Mol Sci
  
  Volume: 20(22) Issue: 22 Pages: 5682-5682
- DOI
  10.3390/ijms20225682
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06608, KAKENHI-PROJECT-19K22553, KAKENHI-PUBLICLY-18H04688, KAKENHI-PUBLICLY-18H04797, KAKENHI-PUBLICLY-18H04897, KAKENHI-PROJECT-16H06390, KAKENHI-PROJECT-19H03496
[Journal Article] Phosphoethanolamine Accumulation Protects Cancer Cells under Glutamine Starvation through Downregulation of PCYT22019
- Author(s)
  Osawa T, Shimamura T, Saito K, Hasegawa Y, Ishii N, Nishida M, Ando R, Kondo A, Anwar M, Kato K, Endo K, Yamano S, Kanki Y, Matsumura Y, Minami T, Tanaka T, Anai M, Wada Y, Wanibuchi H, Hayashi M, Hamada A, Yoshida M, Yachida S, Nakao M, Sakai J, Aburatani H, Shibuya M, Hanada K, Miyano S, Soga T, Kodama T
- Journal Title
  
  Cell Rep.
  
  Volume: 29(1) Issue: 1 Pages: 89-103
- DOI
  10.1016/j.celrep.2019.08.087
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-15H05912, KAKENHI-PUBLICLY-18H04688, KAKENHI-PUBLICLY-18H04797, KAKENHI-PUBLICLY-18H04798, KAKENHI-PUBLICLY-18H04897, KAKENHI-PUBLICLY-19H05210, KAKENHI-PROJECT-16H06390, KAKENHI-PROJECT-19H01031, KAKENHI-PROJECT-17H03614, KAKENHI-PROJECT-19H03496, KAKENHI-PROJECT-18K16132
[Journal Article] Regnase-1-mediated post-transcriptional regulation is essential for hematopoietic stem and progenitor cell homeostasis2019
- Author(s)
  Kidoya H, Muramatsu F, Shimamura T, Jia W, Satoh T, Hayashi Y, Naito H, Kunisaki Y, Arai F, Seki M, Suzuki Y, Osawa T, Akira S., Takakura N
- Journal Title
  
  Nature Commun
  
  Volume: 10 Pages: 1072-1072
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-18H04897
[Journal Article] Phosphoethanolamine Accumulation Protects Cancer Cells under Glutamine Starvation through Downregulation of PCYT22019
- Author(s)
  Osawa.T, Shimamura T, Soga T, Kodama T
- Journal Title
  
  Cell Reports
  
  Volume: 29 Pages: 89-103
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22553
[Journal Article] Regnase-1-mediated post-transcriptional regulation is essential for hematopoietic stem and progenitor cell homeostasis2019
- Author(s)
  Kidoya H, Muramatsu F, Shimamura T, Jia W, Satoh T, Hayashi Y, Naito H, Kunisaki Y, Arai F, Seki M, Suzuki Y, Osawa T, Akira S., Takakura N.
- Journal Title
  
  Nature Commun,
  
  Volume: 10 Issue: 1 Pages: 1072-1072
- DOI
  10.1038/s41467-019-09028-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04797, KAKENHI-PUBLICLY-18H04897, KAKENHI-PROJECT-16H02470, KAKENHI-PROJECT-17H04208, KAKENHI-PROJECT-15H05325, KAKENHI-PROJECT-26710005, KAKENHI-PROJECT-19K22553, KAKENHI-PROJECT-19K16742, KAKENHI-PUBLICLY-18H04798, KAKENHI-PUBLICLY-19H05210, KAKENHI-PROJECT-18H02841, KAKENHI-PROJECT-19H03496
[Journal Article] Overexpression of p54nrb/NONO induces differential EPHA6 splicing and contributes to castration-resistant prostate cancer growth2018
- Author(s)
  Yamamoto R, Osawa T, Sasaki Y, Yamamoto S, Anai M, Izumi K, Matsumura Y, Sakai J, Aburatani H, Mizokami A, Kodama T, Tanaka T
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 12 Pages: 10510-10524
- DOI
  10.18632/oncotarget.24063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26710005, KAKENHI-PUBLICLY-16H01567, KAKENHI-PROJECT-16K14605, KAKENHI-PROJECT-16H06390
[Journal Article] Long Noncoding RNA JHDM1D-AS1 Promotes Tumor Growth by Regulating Angiogenesis in Response to Nutrient Starvation2017
- Author(s)
  Kondo A, Nonaka A, Shimamura T, Yamamoto S, Yoshida T, Kodama T, Aburatani H, Osawa T
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 37 Issue: 18
- DOI
  10.1128/mcb.00125-17
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K14987, KAKENHI-PROJECT-26710005, KAKENHI-PUBLICLY-16H01567, KAKENHI-PROJECT-15K12139, KAKENHI-PROJECT-16K14605, KAKENHI-PROJECT-15H05325
[Journal Article] Dynamically and epigenetically coordinated GATA/ETS/SOX transcription is indispensable for endothelial cell differentiation2017
- Author(s)
  Kanki Y, Nakaki R, Shimamura T, Matsunaga T, Yamamizu K, Katayama S, Suehiro JI, Osawa T, Aburatani H, Kodama T, Wada Y, Yamashita JK, Minami T.
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 印刷中 Issue: 8 Pages: 4344-4358
- DOI
  10.1093/nar/gkx159
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01348, KAKENHI-PROJECT-26250041, KAKENHI-PROJECT-26290035, KAKENHI-PROJECT-26710013, KAKENHI-PROJECT-26430121, KAKENHI-PROJECT-15K12139, KAKENHI-PROJECT-16K15438, KAKENHI-PROJECT-15KK0251, KAKENHI-PROJECT-26710005, KAKENHI-PUBLICLY-16H01567, KAKENHI-PROJECT-17H03580, KAKENHI-PROJECT-17H03614, KAKENHI-PROJECT-16K14605, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-15H05325
[Journal Article] A subset of cerebrovascular pericytes originates from mature macrophages in the very early phase of vascular development in CNS.2017
- Author(s)
  S. Yamamoto, M. Muramatsu, E. Azuma, M. Ikutani, Y. Nagai, H. Sagara, B.N. Koo, S. Kita, E. O’Donnell, T. Osawa, H. Takahashi, K.I. Takano, M. Dohmoto, M. Sugimori, I. Usui, Y. Watanabe, N. Hatakeyama, T. Iwamoto, I. Komuro, K. Takatsu, K. Tobe, S. Niida, N. Matsuda, M. Shibuya, M. Sasahara
- Journal Title
  
  Sci Rep
  
  Volume: 7：3855 Issue: 1 Pages: 1-16
- DOI
  10.1038/s41598-017-03994-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08565, KAKENHI-PROJECT-16K09777, KAKENHI-PROJECT-17K15622, KAKENHI-PROJECT-26710005, KAKENHI-PUBLICLY-16H01567, KAKENHI-PROJECT-17H04062, KAKENHI-PROJECT-15K08527, KAKENHI-PROJECT-16K14605
[Journal Article] Extracellular Acidic pH Activates the Sterol Regulatory Element-binding Protein 2 to Promote Tumor Progression2017
- Author(s)
  Kondo A, Yamamoto S, Nakaki R, Shimamura T, Hamakubo T, Sakai J, Kodama T, Yoshida T, Aburatani H and Osawa T
- Journal Title
  
  Cell Reports
  
  Volume: 18 Issue: 9 Pages: 2228-2242
- DOI
  10.1016/j.celrep.2017.02.006
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01567, KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-26710005, KAKENHI-PROJECT-15K12139, KAKENHI-PROJECT-16K14605, KAKENHI-PROJECT-16H06390, KAKENHI-PROJECT-15H05325
[Journal Article] Establishment of an extracellular acidic pH culture system2017
- Author(s)
  Kondo A & Osawa T
- Journal Title
  
  J Vis Exp.
  
  Volume: 129 Issue: 129
- DOI
  10.3791/56660
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26710005, KAKENHI-PUBLICLY-16H01567, KAKENHI-PROJECT-16K14605
[Journal Article] BMP4/Thrombospondin-1 loop paracrinically inhibits tumor angiogenesis and suppresses the growth of solid tumors2014
- Author(s)
  Tsuchida R, Osawa T, Wang F, Nishii R, Das B, Tsuchida S, Muramatsu M, Takahashi T, Inoue T, Wada Y, Minami T, Yuasa Y, Shibuya M
- Journal Title
  
  Oncogene
  
  Volume: 33 Issue: 29 Pages: 3803-3811
- DOI
  10.1038/onc.2013.358
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23300342, KAKENHI-PROJECT-23701047, KAKENHI-PUBLICLY-24116509, KAKENHI-PROJECT-24650609, KAKENHI-PROJECT-25893063, KAKENHI-PUBLICLY-26116711, KAKENHI-PROJECT-26461568, KAKENHI-PUBLICLY-25134706, KAKENHI-PROJECT-26710005
[Journal Article] Targeting cancer cells resistant to hypoxia and nutrient starvation to improve anti-angiogeneic therapy2013
- Author(s)
  Osawa T (Co-correspondence) and Shibuya M
- Journal Title
  
  Cell Cycle
  
  Volume: Aug 15;12(16) Pages: 2519-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701047
[Journal Article] The Calcineurin-NFAT-Angiopoietin-2 Signaling Axis in Lung Endothelium Is Critical for the Establishment of Lung Metastases2013
- Author(s)
  Minami T, Jiang S, Schadler K, Suehiro JI, Osawa T, Oike Y, Miura M, Naito M, Kodama T, Ryeom S
- Journal Title
  
  Cell Reports
  
  Volume: Aug 14. pii:S2211-1247(13) Issue: 4 Pages: 383-5
- DOI
  10.1016/j.celrep.2013.07.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701047, KAKENHI-PUBLICLY-24116509, KAKENHI-PROJECT-24700969, KAKENHI-PUBLICLY-25134706
[Journal Article] Inhibition of histone demethylase JMJD1A improves anti-angiogenic therapy and reduces tumor-associated macrophages2013
- Author(s)
  Osawa T, Tsuchida R, Muramatsu M, Shimamura T, Wang F, Suehiro J, Kanki Y, Wada Y, Yuasa Y, Aburatani H, Miyano S, Minami T, Kodama T, and Shibuya M
- Journal Title
  
  Cancer Research
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701047
[Journal Article] Inhibition of histone demethylase JMJD1A improves anti-angiogenic therapy and reduces tumor associated macrophages2013
- Author(s)
  Osawa T (Co-correspondence), Tsuchida R, Muramatsu M, Shimamura T, Wang F, Suehiro J, Kanki Y, Wada Y, Yuasa Y, Aburatani H, Miyano S, Minami T, Kodama T, and Shibuya M
- Journal Title
  
  Cancer Research
  
  Volume: May 15;73(10) Pages: 3019-3028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701047
[Journal Article] Inhibition of histone demethylase JMJD1A improves anti-angiogenic therapy and reduces tumor-associated macrophages2013
- Author(s)
  Osawa T, Tsuchida R, Muramatsu M, Shimamura T, Wang F, Suehiro J, Kanki Y, Wada Y, Yuasa Y, Aburatani H, Miyano S, Minami T, Kodama T, and Shibuya M
- Journal Title
  
  Cancer Research
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24116509
[Journal Article] A major role for RCAN1 in atherosclerosis progression2013
- Author(s)
  Mendez-Barbero N, Esteban V, Villahoz S, Escolano A, Urso K, Alfranca A, Rodriguez C, Sanchez SA, Osawa T, Andres V, Martinez-Gonzalez J, Minami T, Redondo JM, Campanero MR
- Journal Title
  
  EMBO Mol Med.
  
  Volume: Dec;5(12) Issue: 12 Pages: 1901-17
- DOI
  10.1002/emmm.201302842
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701047, KAKENHI-PUBLICLY-24116509, KAKENHI-PUBLICLY-25134706
[Journal Article] Inhibition of histone demethylase JMJD1A improves anti-angiogenic therapy and reduces tumor associated macrophages2013
- Author(s)
  Shimamura T, Wang F, Suehiro J, Kanki Y, Wada Y, Yuasa Y, Aburatani H, Miyano S, Minami T, Kodama T, Shibuya M
- Journal Title
  
  Cancer Res
  
  Volume: 73 Issue: 10 Pages: 3019-3028
- DOI
  10.1158/0008-5472.can-12-3231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300342, KAKENHI-PROJECT-23701047, KAKENHI-PUBLICLY-24116509, KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-24650609, KAKENHI-PROJECT-24700969, KAKENHI-PROJECT-24710227, KAKENHI-PUBLICLY-25118505, KAKENHI-PUBLICLY-25125707, KAKENHI-PUBLICLY-25134706, KAKENHI-PROJECT-25730173, KAKENHI-PROJECT-25893063
[Journal Article] Targeting cancer cells resistant to hypoxia and nutrient starvation to improve anti-angiogeneic therapy2013
- Author(s)
  Osawa T and Shibuya
- Journal Title
  
  Cell Cycle
  
  Volume: 12 Issue: 16 Pages: 2519-20
- DOI
  10.4161/cc.25729
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701047, KAKENHI-PUBLICLY-24116509, KAKENHI-PUBLICLY-25134706
[Journal Article] Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell.2012
- Author(s)
  Yae T, Tsuchihashi K, Ishimoto T, Motohara T, Yoshikawa M, Yoshida GJ, Wada T, Masuko T,Mogushi K, Tanaka H, Osawa T, Kanki Y, et al
- Journal Title
  
  Nature Communications
  
  Volume: 6;3 Issue: 1 Pages: 883-883
- DOI
  10.1038/ncomms1892
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310117, KAKENHI-PROJECT-23701047, KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-24590389, KAKENHI-PROJECT-24591176, KAKENHI-PROJECT-24591912, KAKENHI-PROJECT-24710227, KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130007, KAKENHI-PUBLICLY-24116509
[Journal Article] Mechanism of cell death resulting from DNA interstrand cross-linking in mammalian cells2011
- Author(s)
  Osawa T, Davies D, and Hartley JA
- Journal Title
  
  Cell Death and Disease
  
  Volume: Aug 4; 2 Issue: 8 Pages: e187-e187
- DOI
  10.1038/cddis.2011.70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701047
[Journal Article] Human glioblastoma cells exposed to long-term hypoxia and nutrient starvation stimulated induction of secondary T cell leukemia in mice2011
- Author(s)
  Osawa T, et al.
- Journal Title
  
  Blood Cancer J.
  
  Volume: 1 Issue: 2 Pages: e6-e6
- DOI
  10.1038/bcj.2011.5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300342, KAKENHI-PROJECT-23701047
[Journal Article] Down-regulation of receptor activated C-kinase 1 (RACK1) suppresses tumor growth by inhibiting tumor cell proliferation and tumor-associated angiogenesis2011
- Author(s)
  Wang F, Osawa T, Tsuchida R, Yuasa Y, and Shibuya M
- Journal Title
  
  Cancer Science.
  
  Volume: Nov;102(11) Pages: 2007-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701047
[Journal Article] Increased expression of histone demethylase JHDM1D under nutrient starvation suppresses tumor growth via downregulating angiogenesis2011
- Author(s)
  Osawa T, Muramatsu M, Tsuchida R, Wang F, Kodama T, Minami T and Shibuya M
- Journal Title
  
  PNAS
  
  Volume: Dec 20;108(51) Pages: 20725-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701047
[Journal Article] Increased expression of histone demethylase JHDM1D under nutrient starvation suppresses tumor growth via downregulating angiogenesis2011
- Author(s)
  Osawa T., et al.
- Journal Title
  
  PNAS
  
  Volume: 108 Pages: 20725-20729
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701047
[Journal Article] Downregulation of receptor for activated C-kinase 1 (RACK1) suppresses tumor growth by inhibiting tumor cell proliferation and tumor-associated angiogenesis2011
- Author(s)
  王峰、土田里香
- Journal Title
  
  Cancer Science
  
  Volume: 102(11) Issue: 11 Pages: 2007-13
- DOI
  10.1111/j.1349-7006.2011.02065.x
- NAID
  10030244997
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J40024, KAKENHI-PROJECT-23701047
[Journal Article] RACK1 regulates VEGF/Flt-1-mediated cell migration via activation of a PI3-K/Akt pathway2011
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  Wang F., Yamauchi M., Muramatsu M., Osawa T., et al.
- Journal Title
  
  J Biol Chem.
  
  Volume: 286 Pages: 9097-9106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701047
[Patent] 含フッ素アミノ酸2022
- Inventor(s)
  大澤毅ら
- Industrial Property Rights Holder
  大澤毅ら
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-19H03496
[Patent] 神経芽腫の診断に用いる新たな尿中代謝物2022
- Inventor(s)
  大澤毅ら
- Industrial Property Rights Holder
  大澤毅ら
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-010494
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-21K19399
[Patent] 横紋筋肉腫の検出方法およびそのバイオマーカー2022
- Inventor(s)
  大澤毅ら
- Industrial Property Rights Holder
  大澤毅ら
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-168633
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-21K19399
[Patent] 神経芽腫の診断に用いる新たな尿中代謝物2022
- Inventor(s)
  大澤毅ら
- Industrial Property Rights Holder
  大澤毅ら
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-010494
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-19H03496
[Patent] 神経芽腫の診断に用いる新たな尿中代謝物2022
- Inventor(s)
  大澤毅ら
- Industrial Property Rights Holder
  大澤毅ら
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-010494
- Filing Date
  2022
- Data Source
  KAKENHI-PUBLICLY-20H04834
[Patent] 横紋筋肉腫の検出方法およびそのバイオマーカー2022
- Inventor(s)
  大澤毅ら
- Industrial Property Rights Holder
  大澤毅ら
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-168633
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-19H03496
[Patent] 含フッ素アミノ酸2022
- Inventor(s)
  大澤毅ら
- Industrial Property Rights Holder
  大澤毅ら
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-21K19399
[Patent] 検体チューブ及び分注デッキ2021
- Inventor(s)
  大澤毅ら
- Industrial Property Rights Holder
  大澤毅ら
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-055060
- Filing Date
  2021
- Data Source
  KAKENHI-PUBLICLY-20H04834
[Patent] 検体チューブ及び分注デッキ2021
- Inventor(s)
  大澤毅ら
- Industrial Property Rights Holder
  大澤毅ら
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-055060
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-21K19399
[Patent] 検体チューブ及び分注デッキ2021
- Inventor(s)
  大澤毅ら
- Industrial Property Rights Holder
  大澤毅ら
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-055060
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-19H03496
[Patent] 抗腫瘍剤2010
- Inventor(s)
  澁谷正史、土田里香、大澤毅
- Industrial Property Rights Holder
  東京医科歯科大学
- Industrial Property Rights Type
  特許
- Acquisition Date
  2010
- Overseas
- Data Source
  KAKENHI-PROJECT-23701047
[Presentation] 腫瘍微小環境における免疫細胞を介した代謝適応機構2023
- Author(s)
  大澤毅
- Organizer
  第7回理論生物学ワークショップ
- Invited
- Data Source
  KAKENHI-PROJECT-21K19399
[Presentation] 腫瘍微小環境における免疫細胞を介した代謝適応機構2023
- Author(s)
  大澤毅
- Organizer
  第7回理論生物学ワークショップ
- Invited
- Data Source
  KAKENHI-PROJECT-19H03496
[Presentation] 高深度ニュートリオミクスから迫るがん悪性化機構の解明2023
- Author(s)
  大澤毅
- Organizer
  計算疾患システム生物学シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-23K18234
[Presentation] 高深度オミクスから迫るがん悪性化機構の解明2023
- Author(s)
  大澤毅
- Organizer
  第８回理論免疫学ワークショップ
- Invited
- Data Source
  KAKENHI-PROJECT-23K18234
[Presentation] 高深度ニュートリオミクスから迫るがん悪性化機構の解明2023
- Author(s)
  大澤毅
- Organizer
  第46回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K18234
[Presentation] 腫瘍微小環境における特異的な代謝リプログラミング2022
- Author(s)
  大澤毅
- Organizer
  第22回日本抗加齢医学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19399
[Presentation] ニュートリオミクスから迫るオルガネラダイナミクス2022
- Author(s)
  大澤毅
- Organizer
  iSeminar (異分野融合セミナー)
- Invited
- Data Source
  KAKENHI-PROJECT-19H03496
[Presentation] 腫瘍微小環境における代謝変化を抑制するオルガネラダイナミクス2022
- Author(s)
  大澤毅
- Organizer
  第81回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03496
[Presentation] Cancer Metabolism within tumor microenvironments2022
- Author(s)
  Tsuyoshi Osawa
- Organizer
  12th AACR-JCA Joint Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03496
[Presentation] 腫瘍微小環境における特異的な代謝リプログラミング2022
- Author(s)
  大澤毅
- Organizer
  第22回日本抗加齢医学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03496
[Presentation] 肝内胆管がんのゲノム多様性を凌駕しておこるBCAA代謝機構2022
- Author(s)
  大澤毅, 北川彰洋, 三森功士
- Organizer
  第26回日本がん分子標的治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03496
[Presentation] ニュートリオミクスから迫るオルガネラダイナミクス2022
- Author(s)
  大澤毅
- Organizer
  iSeminar (異分野融合セミナー)
- Invited
- Data Source
  KAKENHI-PROJECT-21K19399
[Presentation] 肝内胆管がんのゲノム多様性を凌駕しておこるBCAA代謝機構2022
- Author(s)
  大澤毅
- Organizer
  第26回日本がん分子標的治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19399
[Presentation] 腫瘍微小環境における代謝変化を抑制するオルガネラダイナミクス2022
- Author(s)
  大澤毅
- Organizer
  第81回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19399
[Presentation] Cancer Metabolism within tumor microenvironments2022
- Author(s)
  Tsuyoshi Osawa
- Organizer
  12th AACR-JCA Joint Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19399
[Presentation] がんと代謝2022 (Years in Review)2022
- Author(s)
  大澤毅
- Organizer
  第81回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19399
[Presentation] がんと代謝2022 (Years in Review)2022
- Author(s)
  大澤毅
- Organizer
  第81回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03496
[Presentation] ニュートリオミクス、がんと代謝2021
- Author(s)
  大澤毅
- Organizer
  第２５回日本がん分子標的治療学会学術集会
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H04834
[Presentation] がん微小環境におけるがん細胞と線維芽細胞の代謝相互作用2021
- Author(s)
  大澤毅
- Organizer
  第80回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19399
[Presentation] がん微小環境におけるがん細胞と線維芽細胞の代謝相互作用2021
- Author(s)
  大澤毅
- Organizer
  第80回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03496
[Presentation] 造血細胞、エクソソーム、多階層オミクス解析からみる全身性疾患生物学2021
- Author(s)
  大澤毅
- Organizer
  第94回日本生化学会
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H04834
[Presentation] がん微小環境におけるエピジェネティック制御2021
- Author(s)
  大澤毅
- Organizer
  第１４回日本エピジェネティクス研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03496
[Presentation] ニュートリオミクスから迫るがん悪性化機構の解明2021
- Author(s)
  大澤毅
- Organizer
  第121回北海道癌談話会春季シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19H03496
[Presentation] がん微小環境におけるエピジェネティック制御2021
- Author(s)
  大澤毅
- Organizer
  第１４回日本エピジェネティクス研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19399
[Presentation] がん微小環境におけるがん細胞と線維芽細胞の代謝相互作用2021
- Author(s)
  大澤毅
- Organizer
  第80回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H04834
[Presentation] ニュートリオミクス、がんと代謝2021
- Author(s)
  大澤毅
- Organizer
  第２５回日本がん分子標的治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03496
[Presentation] 造血細胞、エクソソーム、多階層オミクス解析からみる全身性疾患生物学2021
- Author(s)
  大澤毅
- Organizer
  94回日本生化学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19399
[Presentation] ニュートリオミクス、がんと代謝2021
- Author(s)
  大澤毅
- Organizer
  第２５回日本がん分子標的治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19399
[Presentation] がん微小環境におけるエピジェネティック制御2021
- Author(s)
  大澤毅
- Organizer
  第１４回日本エピジェネティクス研究会
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H04834
[Presentation] ニュートリオミクスから迫るがん悪性化機構の解明2021
- Author(s)
  大澤毅
- Organizer
  第121回北海道癌談話会春季シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21K19399
[Presentation] ニュートリオミクスから迫るがん悪性化機構の解明2021
- Author(s)
  大澤毅
- Organizer
  第121回北海道癌談話会春季シンポジウム
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H04834
[Presentation] 造血細胞、エクソソーム、多階層オミクス解析からみる全身性疾患生物学2021
- Author(s)
  大澤毅
- Organizer
  第94回日本生化学会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03496
[Presentation] Integrative Nutriomics Approach for understanding Cancer and Metabolism2020
- Author(s)
  大澤　毅
- Organizer
  International Conference on Cancer Systems Biology Beyond
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22553
[Presentation] Tumor Microenvironmental Metabolic Adaptation induces Tumor Progression2020
- Author(s)
  Osawa T
- Organizer
  Establishing International Research Network of Mathematical Oncology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22553
[Presentation] Metabolic dynamics wthin tumor microenvironments towards cancer plasticity2020
- Author(s)
  大澤ら
- Organizer
  第７９回日本癌学会
- Data Source
  KAKENHI-PROJECT-19K22553
[Presentation] Integrative Nutriomics Approach for understanding Cancer and Metabolism2020
- Author(s)
  大澤　毅
- Organizer
  International Conference on Cancer Systems Biology Beyond
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03496
[Presentation] Integrative Nutriomics Approach for understanding Cancer and Metabolism2020
- Author(s)
  Osawa T
- Organizer
  International Conference on Cancer Systems Biology Beyond
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03496
[Presentation] Integrative Nutriomics Approach for understanding Cancer and Metabolism2020
- Author(s)
  大澤　毅
- Organizer
  International Conference on Cancer Systems Biology Beyond
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04797
[Presentation] Integrative Nutriomics Approach for understanding Cancer and Metabolism2020
- Author(s)
  大澤　毅
- Organizer
  International Conference on Cancer Systems Biology Beyond
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04897
[Presentation] Integrative Nutriomics Approach for understanding Cancer and Metabolism2020
- Author(s)
  Osawa T
- Organizer
  International Conference on Cancer Systems Biology Beyond
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H04834
[Presentation] Adaptation of Cancer cells against amino acid deprivation to promote tumor progression2019
- Author(s)
  大澤　毅
- Organizer
  2019 Spring International Convention of The Pharmaceutical Society of Korea
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04897
[Presentation] がん細胞におけるグルタミン欠乏適応機構の解明2019
- Author(s)
  大澤　毅
- Organizer
  第7回がんと代謝研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03496
[Presentation] Glutamine Deprivation Promotes Tumor Progression through Down-regulation of PCYT22019
- Author(s)
  Osawa T et al.
- Organizer
  第１１回JCA-AACR Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04797
[Presentation] Glutamine Deprivation Promotes Tumor Progression through Down-regulation of PCYT22019
- Author(s)
  Osawa T et al.
- Organizer
  第１１回JCA-AACR Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26710005
[Presentation] Glutamine Deprivation Promotes Tumor Progression through Down-regulation of PCYT22019
- Author(s)
  Osawa T et al.
- Organizer
  第１１回JCA-AACR Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04897
[Presentation] Information and life science fusion brings innovation-To break through the limits of omics analysis2019
- Author(s)
  大澤　毅
- Organizer
  The 42nd Annual Meeting of the Molecular Biology Society of Japan
- Invited
- Data Source
  KAKENHI-PROJECT-19K22553
[Presentation] Information and life science fusion brings innovation-To break through the limits of omics analysis2019
- Author(s)
  大澤　毅
- Organizer
  The 42nd Annual Meeting of the Molecular Biology Society of Japan
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04897
[Presentation] Information and life science fusion brings innovation-To break through the limits of omics analysis2019
- Author(s)
  大澤　毅
- Organizer
  The 42nd Annual Meeting of the Molecular Biology Society of Japan
- Invited
- Data Source
  KAKENHI-PROJECT-19H03496
[Presentation] Adaptation of Cancer cells against amino acid deprivation to promote tumor progression2019
- Author(s)
  大澤　毅
- Organizer
  2019 Spring International Convention of The Pharmaceutical Society of Korea
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04797
[Presentation] Adaptation of Cancer cells against amino acid deprivation to promote tumor progression2019
- Author(s)
  大澤　毅
- Organizer
  2019 Spring International Convention of The Pharmaceutical Society of Korea
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03496
[Presentation] Information and life science fusion brings innovation-To break through the limits of omics analysis2019
- Author(s)
  大澤　毅
- Organizer
  The 42nd Annual Meeting of the Molecular Biology Society of Japan
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04797
[Presentation] Tumor progression though amino acids metabolic shift2019
- Author(s)
  大澤　毅
- Organizer
  The 78th Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PUBLICLY-18H04897
[Presentation] がん細胞におけるグルタミン欠乏適応機構の解明2019
- Author(s)
  大澤　毅
- Organizer
  第7回がんと代謝研究会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04797
[Presentation] Adaptation of Cancer cells against amino acid deprivation to promote tumor progression2019
- Author(s)
  大澤　毅
- Organizer
  2019 Spring International Convention of The Pharmaceutical Society of Korea
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22553
[Presentation] Tumor progression though amino acids metabolic shift2019
- Author(s)
  大澤　毅
- Organizer
  The 78th Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PUBLICLY-18H04797
[Presentation] Integrative understanding and control of biological phenomena through specio-temporal omics2019
- Author(s)
  大澤　毅
- Organizer
  The 92nd Annual Meeting of the Japanese Biochemical Society
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04897
[Presentation] がん細胞におけるグルタミン欠乏適応機構の解明2019
- Author(s)
  大澤　毅
- Organizer
  第7回がんと代謝研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22553
[Presentation] Integrative understanding and control of biological phenomena through specio-temporal omics2019
- Author(s)
  大澤　毅
- Organizer
  The 92nd Annual Meeting of the Japanese Biochemical Society
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04797
[Presentation] Tumor progression though amino acids metabolic shift2019
- Author(s)
  大澤　毅
- Organizer
  The 78th Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-19H03496
[Presentation] がん細胞におけるグルタミン欠乏適応機構の解明2019
- Author(s)
  大澤　毅
- Organizer
  第7回がんと代謝研究会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04897
[Presentation] Integrative understanding and control of biological phenomena through specio-temporal omics2019
- Author(s)
  大澤　毅
- Organizer
  The 92nd Annual Meeting of the Japanese Biochemical Society
- Invited
- Data Source
  KAKENHI-PROJECT-19H03496
[Presentation] Integrative understanding and control of biological phenomena through specio-temporal omics2019
- Author(s)
  大澤　毅
- Organizer
  The 92nd Annual Meeting of the Japanese Biochemical Society
- Invited
- Data Source
  KAKENHI-PROJECT-19K22553
[Presentation] Tumor progression though amino acids metabolic shift2019
- Author(s)
  大澤　毅
- Organizer
  The 78th Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-19K22553
[Presentation] ニュートリオミクスでがん悪性化機構を解き明かす2018
- Author(s)
  大澤毅
- Organizer
  第４１回日本分子生物学会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04797
[Presentation] ニュートリオミクスでがん悪性化機構を解き明かす2018
- Author(s)
  大澤毅
- Organizer
  第４１回日本分子生物学会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04897
[Presentation] Comprehensive Nutriomics Approach Reveals Mechanism of Tumor Aggressiveness2018
- Author(s)
  Osawa T
- Organizer
  16th Korea-Japan Joint Symposium on Vascular Biology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04897
[Presentation] アミノ酸飢餓における代謝変動ががんの悪性化に寄与する2018
- Author(s)
  大澤毅ら
- Organizer
  第７７回日本癌学会学術大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26710005
[Presentation] Comprehensive Nutriomics Approach Reveals Mechanism of Tumor Aggressiveness2018
- Author(s)
  Osawa T
- Organizer
  16th Korea-Japan Joint Symposium on Vascular Biology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04797
[Presentation] アミノ酸飢餓における代謝変動ががんの悪性化に寄与する2018
- Author(s)
  大澤毅ら
- Organizer
  第７７回日本癌学会学術大会
- Data Source
  KAKENHI-PUBLICLY-18H04897
[Presentation] Glutamine Deprivation Promotes Tumor Progression through Down-regulation of PCYT22018
- Author(s)
  Osawa T et al.
- Organizer
  コールドスプリングハーバーミーティング
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04797
[Presentation] ニュートリオミクスでがん悪性化機構を解き明かす2018
- Author(s)
  大澤毅
- Organizer
  第４１回日本分子生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-26710005
[Presentation] Glutamine Deprivation Promotes Tumor Progression through Down-regulation of PCYT22018
- Author(s)
  Osawa T et al
- Organizer
  コールドスプリングハーバーミーティング
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26710005
[Presentation] Comprehensive Nutriomics Approach Reveals Mechanism of Tumor Aggressiveness2018
- Author(s)
  Osawa T
- Organizer
  16th Korea-Japan Joint Symposium on Vascular Biology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26710005
[Presentation] Glutamine Deprivation Promotes Tumor Progression through Down-regulation of PCYT22018
- Author(s)
  Osawa T et al.
- Organizer
  コールドスプリングハーバーミーティング
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04897
[Presentation] アミノ酸飢餓における代謝変動ががんの悪性化に寄与する2018
- Author(s)
  大澤毅ら
- Organizer
  第７７回日本癌学会学術大会
- Data Source
  KAKENHI-PUBLICLY-18H04797
[Presentation] がん代謝と血管生物学の融合を目指して2017
- Author(s)
  大澤毅ら
- Organizer
  第３回血管生物若手研究会
- Place of Presentation
  淡路夢舞台国際会議場（兵庫県）
- Year and Date
  2017-03-03
- Invited
- Data Source
  KAKENHI-PROJECT-26710005
[Presentation] ニュートリオミクスから迫るがんの病態解明と治療戦略2017
- Author(s)
  大澤　毅
- Organizer
  ConBio2017
- Invited
- Data Source
  KAKENHI-PROJECT-16K14605
[Presentation] 腫瘍微小環境における細胞膜リン脂質代謝の役割2017
- Author(s)
  大澤　毅
- Organizer
  第5回がんと代謝研究会
- Invited
- Data Source
  KAKENHI-PROJECT-16K14605
[Presentation] Down-regulation of PE Synthesis promotes tumor progression under starvation2017
- Author(s)
  大澤　毅
- Organizer
  第７6回日本癌学会学術総会
- Data Source
  KAKENHI-PUBLICLY-16H01567
[Presentation] Down-regulation of PE Synthesis promotes tumor progression under starvation2017
- Author(s)
  大澤　毅
- Organizer
  第７6回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K14605
[Presentation] 腫瘍微小環境における細胞膜リン脂質代謝の役割2017
- Author(s)
  大澤　毅
- Organizer
  第5回がんと代謝研究会
- Invited
- Data Source
  KAKENHI-PROJECT-26710005
[Presentation] がん代謝と血管生物学の融合を目指して2017
- Author(s)
  大澤毅ら
- Organizer
  第３回血管生物若手研究会
- Place of Presentation
  淡路夢舞台国際会議場（兵庫県）
- Year and Date
  2017-03-03
- Invited
- Data Source
  KAKENHI-PROJECT-16K14605
[Presentation] ニュートリオミクスから迫るがんの病態解明と治療戦略2017
- Author(s)
  大澤　毅
- Organizer
  ConBio2017
- Invited
- Data Source
  KAKENHI-PROJECT-26710005
[Presentation] ニュートリオミクスから迫るがんの病態解明と治療戦略2017
- Author(s)
  大澤　毅
- Organizer
  ConBio2017
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01567
[Presentation] がん代謝と血管生物学の融合を目指して2017
- Author(s)
  大澤毅ら
- Organizer
  第３回血管生物若手研究会
- Place of Presentation
  淡路夢舞台国際会議場（兵庫県）
- Year and Date
  2017-03-03
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01567
[Presentation] 腫瘍微小環境における細胞膜リン脂質代謝の役割2017
- Author(s)
  大澤　毅
- Organizer
  第5回がんと代謝研究会
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01567
[Presentation] Down-regulation of PE Synthesis promotes tumor progression under starvation2017
- Author(s)
  大澤　毅
- Organizer
  第７6回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-26710005
[Presentation] 腫瘍微小環境から捉えたがん代謝2016
- Author(s)
  大澤毅
- Organizer
  御茶ノ水がん学アカデミア第１２２回集会
- Place of Presentation
  東京
- Year and Date
  2016-03-23
- Invited
- Data Source
  KAKENHI-PUBLICLY-26116711
[Presentation] Phosphoethanolamine Stimulates Cancer Cell Toerance against Nutrient Starvation through Alteration of PE Biosynthesis2016
- Author(s)
  大澤毅ら
- Organizer
  第７５回日本癌学会
- Place of Presentation
  パシフィコ横浜(神奈川県）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26710005
[Presentation] メタボロミクスによる新規オンコメタボライトPEtnの発見2016
- Author(s)
  大澤毅
- Organizer
  第一回生活習慣病とがんの代謝栄養メカニズム研究会（最優秀ポスター賞受賞）
- Place of Presentation
  東京
- Year and Date
  2016-02-27
- Data Source
  KAKENHI-PUBLICLY-26116711
[Presentation] マルチオミクスが解き明かす腫瘍微小環境とがん代謝2016
- Author(s)
  大澤毅
- Organizer
  第８９回日本生化学会大会
- Place of Presentation
  仙台国際センター（宮城県）
- Year and Date
  2016-09-25
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01567
[Presentation] 癌代謝物エタノールアミンリンは低栄養のがんの生存に寄与する2016
- Author(s)
  大澤ら
- Organizer
  第２回血管生物医学会若手研究会
- Place of Presentation
  仙台
- Year and Date
  2016-03-04
- Invited
- Data Source
  KAKENHI-PUBLICLY-26116711
[Presentation] がん微小環境と代謝エピエノム制御の研究2016
- Author(s)
  大澤毅
- Organizer
  第２５回日本がん転移学会
- Place of Presentation
  米子コンベンションセンター（鳥取県）
- Year and Date
  2016-07-20
- Invited
- Data Source
  KAKENHI-PROJECT-26710005
[Presentation] 腫瘍微小環境から捉えたがんの代謝戦略2016
- Author(s)
  大澤毅
- Organizer
  第４回がんと代謝研究会
- Place of Presentation
  かごしま県民交流センター（鹿児島県）
- Year and Date
  2016-07-07
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01567
[Presentation] メタボロミクスによる新規オンコメタボライトPEtnの発見2016
- Author(s)
  大澤毅
- Organizer
  第一回生活習慣病とがんの代謝栄養メカニズム研究会（最優秀ポスター賞受賞）
- Place of Presentation
  東京
- Year and Date
  2016-02-27
- Data Source
  KAKENHI-PROJECT-26710005
[Presentation] Phosphoethanolamine Stimulates Cancer Cell Toerance against Nutrient Starvation through Alteration of PE Biosynthesis2016
- Author(s)
  大澤毅ら
- Organizer
  第７５回日本癌学会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K14605
[Presentation] 栄養飢餓におけるがんのトランスメタボロミクス2016
- Author(s)
  大澤毅
- Organizer
  第３９回日本分子生物学会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-PROJECT-16K14605
[Presentation] がん微小環境と代謝エピエノム制御の研究2016
- Author(s)
  大澤毅
- Organizer
  第２５回日本がん転移学会
- Place of Presentation
  米子コンベンションセンター（鳥取県）
- Year and Date
  2016-07-20
- Invited
- Data Source
  KAKENHI-PROJECT-16K14605
[Presentation] 栄養飢餓におけるがんのトランスメタボロミクス2016
- Author(s)
  大澤毅
- Organizer
  第３９回日本分子生物学会
- Place of Presentation
  パシフィコ横浜(神奈川県）
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01567
[Presentation] 腫瘍微小環境から捉えたがんの代謝戦略2016
- Author(s)
  大澤毅
- Organizer
  第４回がんと代謝研究会
- Place of Presentation
  かごしま県民交流センター（鹿児島県）
- Year and Date
  2016-07-07
- Invited
- Data Source
  KAKENHI-PROJECT-16K14605
[Presentation] 腫瘍微小環境から捉えたがん代謝2016
- Author(s)
  大澤毅
- Organizer
  御茶ノ水がん学アカデミア第１２２回集会
- Place of Presentation
  東京
- Year and Date
  2016-03-23
- Invited
- Data Source
  KAKENHI-PROJECT-26710005
[Presentation] 腫瘍微小環境から捉えたがんの代謝戦略2016
- Author(s)
  大澤毅
- Organizer
  第４回がんと代謝研究会
- Place of Presentation
  かごしま県民交流センター（鹿児島県）
- Year and Date
  2016-07-07
- Invited
- Data Source
  KAKENHI-PROJECT-26710005
[Presentation] マルチオミクスが解き明かす腫瘍微小環境とがん代謝2016
- Author(s)
  大澤毅
- Organizer
  第８９回日本生化学会大会
- Place of Presentation
  仙台国際センター（宮城県）
- Year and Date
  2016-09-25
- Invited
- Data Source
  KAKENHI-PROJECT-26710005
[Presentation] 癌代謝物エタノールアミンリンは低栄養のがんの生存に寄与する2016
- Author(s)
  大澤ら
- Organizer
  第２回血管生物医学会若手研究会
- Place of Presentation
  仙台
- Year and Date
  2016-03-04
- Invited
- Data Source
  KAKENHI-PROJECT-26710005
[Presentation] がん微小環境と代謝エピエノム制御の研究2016
- Author(s)
  大澤毅
- Organizer
  第２5回日本がん転移学会
- Place of Presentation
  米子コンベンションセンター（鳥取県）
- Year and Date
  2016-07-20
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01567
[Presentation] マルチオミクスが解き明かす腫瘍微小環境とがん代謝2016
- Author(s)
  大澤毅
- Organizer
  第８９回日本生化学会大会
- Place of Presentation
  仙台国際センター（宮城県）
- Year and Date
  2016-09-25
- Invited
- Data Source
  KAKENHI-PROJECT-16K14605
[Presentation] 栄養飢餓におけるがんのトランスメタボロミクス2016
- Author(s)
  大澤毅
- Organizer
  第３９回日本分子生物学会
- Place of Presentation
  パシフィコ横浜(神奈川県）
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-PROJECT-26710005
[Presentation] Phosphoethanolamine Stimulates Cancer Cell Toerance against Nutrient Starvation through Alteration of PE Biosynthesis2016
- Author(s)
  大澤毅ら
- Organizer
  第７５回日本癌学会
- Place of Presentation
  パシフィコ横浜(神奈川県）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PUBLICLY-16H01567
[Presentation] Tumor microenvironment and cancer metabolism2015
- Author(s)
  Osawa T
- Organizer
  第46回高松宮妃癌研究基金国際シンポジウム
- Place of Presentation
  東京
- Year and Date
  2015-11-16
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26710005
[Presentation] Cancer cells utilize lipid metabolism under hypoxic and nutrient starved tumor microenvironment2015
- Author(s)
  Osawa T et al.
- Organizer
  春季特別日本血管生物医学会シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2015-05-13
- Invited
- Data Source
  KAKENHI-PROJECT-26710005
[Presentation] マルチオミクス統合解析から捉えた腫瘍微小環境2015
- Author(s)
  大澤ら
- Organizer
  BMB2015（第38回日本分子生物学会年会、第88回日本生化学会大会合同大会）
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-26710005
[Presentation] Cancer cells utilize lipid metabolism under hypoxic and nutrient starved tumor microenvironment2015
- Author(s)
  大澤ら
- Organizer
  第１回血管生物医学若手研究会
- Place of Presentation
  東京
- Year and Date
  2015-02-06
- Invited
- Data Source
  KAKENHI-PUBLICLY-25134706
[Presentation] Cancer cells utilize lipid metabolism under hypoxic and nutrient starved tumor microenvironment2015
- Author(s)
  大澤ら
- Organizer
  第１回血管生物医学若手研究会
- Place of Presentation
  東京
- Year and Date
  2015-02-06
- Invited
- Data Source
  KAKENHI-PROJECT-26710005
[Presentation] オミクス統合解析から捉えた腫瘍微小環境とがん代謝2015
- Author(s)
  大澤ら
- Organizer
  第３回がんと代謝研究会
- Place of Presentation
  金沢
- Year and Date
  2015-07-16
- Invited
- Data Source
  KAKENHI-PUBLICLY-26116711
[Presentation] Tumor microenvironment and cancer metabolism2015
- Author(s)
  Osawa T
- Organizer
  第46回高松宮妃癌研究基金国際シンポジウム
- Place of Presentation
  東京
- Year and Date
  2015-11-16
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26116711
[Presentation] オミクス統合解析から捉えた腫瘍微小環境とがん代謝2015
- Author(s)
  大澤毅
- Organizer
  国立がんセンター東病院悪液質セミナー
- Place of Presentation
  千葉
- Year and Date
  2015-08-05
- Invited
- Data Source
  KAKENHI-PUBLICLY-26116711
[Presentation] Cancer cells utilize lipid metabolism under hypoxic and nutrient starved tumor microenvironment2015
- Author(s)
  Osawa T et al.
- Organizer
  春季特別日本血管生物医学会シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2015-05-13
- Invited
- Data Source
  KAKENHI-PUBLICLY-26116711
[Presentation] メタボロミクスによる新しいオンコメタボライトEAPの発見2015
- Author(s)
  大澤ら
- Organizer
  第２７回高遠シンポジウム
- Place of Presentation
  京都
- Year and Date
  2015-08-26
- Data Source
  KAKENHI-PROJECT-26710005
[Presentation] 低酸素・低栄養で脂肪酸代謝を介して蓄積するオンコメタボライトの解析2015
- Author(s)
  大澤ら
- Organizer
  第７4回日本癌学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PUBLICLY-26116711
[Presentation] Cancer cells utilize lipid metabolism under hypoxia and nutrient starvation2015
- Author(s)
  Osawa T et al.
- Organizer
  18th European Cancer Congress-40th ESMO 2015
- Place of Presentation
  Vienna
- Year and Date
  2015-09-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26710005
[Presentation] オミクス統合解析から捉えた腫瘍微小環境とがん代謝2015
- Author(s)
  大澤ら
- Organizer
  第３回がんと代謝研究会
- Place of Presentation
  金沢
- Year and Date
  2015-07-16
- Invited
- Data Source
  KAKENHI-PROJECT-26710005
[Presentation] Cancer cells utilize lipid metabolism under hypoxia and nutrient starvation2015
- Author(s)
  Osawa T et al.
- Organizer
  18th European Cancer Congress-40th ESMO 2015
- Place of Presentation
  Vienna
- Year and Date
  2015-09-25
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26116711
[Presentation] オミクス統合解析から捉えた腫瘍微小環境とがん代謝2015
- Author(s)
  大澤毅
- Organizer
  国立がんセンター東病院悪液質セミナー
- Place of Presentation
  千葉
- Year and Date
  2015-08-05
- Invited
- Data Source
  KAKENHI-PROJECT-26710005
[Presentation] 低酸素・低栄養で脂肪酸代謝を介して蓄積するオンコメタボライトの解析2015
- Author(s)
  大澤ら
- Organizer
  第７4回日本癌学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26710005
[Presentation] マルチオミクス統合解析から捉えた腫瘍微小環境2015
- Author(s)
  大澤ら
- Organizer
  BMB2015（第38回日本分子生物学会年会、第88回日本生化学会大会合同大会）
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PUBLICLY-26116711
[Presentation] メタボロミクスによる新しいオンコメタボライトEAPの発見2015
- Author(s)
  大澤ら
- Organizer
  第２７回高遠シンポジウム
- Place of Presentation
  京都
- Year and Date
  2015-08-26
- Data Source
  KAKENHI-PUBLICLY-26116711
[Presentation] 腫瘍微小環境におけるエピゲノム制御を介したオンコメタボライトの解析2014
- Author(s)
  大澤ら
- Organizer
  第３７回分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-26710005
[Presentation] 腫瘍微小環境におけるエピゲノム制御を介したオンコメタボライトの解析2014
- Author(s)
  大澤ら
- Organizer
  第３７回分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PUBLICLY-25134706
[Presentation] 低酸素・低栄養の腫瘍微小環境において癌細胞はエピゲノム制御を介して脂質代謝を誘導する2014
- Author(s)
  大澤ら
- Organizer
  第７３回日本癌学会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PUBLICLY-25134706
[Presentation] Histone demethylases regulate tumor angiogenesis and metabolism2014
- Author(s)
  Osawa et al
- Organizer
  第１８回国際血管生物学会
- Place of Presentation
  京都
- Year and Date
  2014-04-14
- Data Source
  KAKENHI-PUBLICLY-25134706
[Presentation] HIstone demetylases regulate tumor angiogenesis and metabolism2014
- Author(s)
  Osawa T et al.
- Organizer
  Keystone Symposia
- Place of Presentation
  Whistler (Canada)
- Data Source
  KAKENHI-PROJECT-23701047
[Presentation] Histone Demetylases regulate tumor angiogenesis and metabolism2014
- Author(s)
  Osawa T
- Organizer
  Keystone Symposia on Metabolism and Angiogenesis
- Place of Presentation
  Whistler, Canada
- Data Source
  KAKENHI-PROJECT-23701047
[Presentation] Demetylases regulate tumor angiogenesis and metabolism2014
- Author(s)
  Osawa T et al.
- Organizer
  Keystone Symposia
- Place of Presentation
  Whistler (Canada)
- Data Source
  KAKENHI-PUBLICLY-24116509
[Presentation] 低酸素・低栄養の腫瘍微小環境において癌細胞はエピゲノム制御を介して脂質代謝を誘導する2014
- Author(s)
  大澤ら
- Organizer
  第７３回日本癌学会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-26710005
[Presentation] 腫瘍微小環境における代謝とシステムバイオロジー2014
- Author(s)
  大澤ら
- Organizer
  第８７回日本生化学会
- Place of Presentation
  京都
- Year and Date
  2014-10-15
- Invited
- Data Source
  KAKENHI-PROJECT-26710005
[Presentation] 腫瘍微小環境における代謝とシステムバイオロジー2014
- Author(s)
  大澤ら
- Organizer
  第８７回日本生化学会
- Place of Presentation
  京都
- Year and Date
  2014-10-15
- Invited
- Data Source
  KAKENHI-PUBLICLY-25134706
[Presentation] 低酸素・低栄養の腫瘍微小環境におけるエネルギー代謝の解明2014
- Author(s)
  大澤
- Organizer
  がん若手ワークショップ
- Place of Presentation
  蓼科
- Year and Date
  2014-09-03
- Data Source
  KAKENHI-PUBLICLY-25134706
[Presentation] 腫瘍微小環境に起因するエピゲノム因子とncRNAの腫瘍増殖機構とsiRNAを用いた増殖抑制2014
- Author(s)
  大澤ら
- Organizer
  第６回日本RNAi研究会
- Place of Presentation
  広島
- Year and Date
  2014-08-28
- Invited
- Data Source
  KAKENHI-PUBLICLY-25134706
[Presentation] 腫瘍微小環境に起因するエピゲノム因子とncRNAの腫瘍増殖機構とsiRNAを用いた増殖抑制2014
- Author(s)
  大澤ら
- Organizer
  第６回日本RNAi研究会
- Place of Presentation
  広島
- Year and Date
  2014-08-28
- Invited
- Data Source
  KAKENHI-PROJECT-26710005
[Presentation] 腫瘍微小環境におけるゲノムワイドなクロマチン及び遺伝子発現解析2014
- Author(s)
  近藤、大澤ら
- Organizer
  第７３回日本癌学会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PUBLICLY-25134706
[Presentation] 腫瘍微小環境におけるゲノムワイドなクロマチン及び遺伝子発現解析2014
- Author(s)
  近藤、大澤ら
- Organizer
  第７３回日本癌学会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-26710005
[Presentation] HIstone demetylases regulate tumor angiogenesis and metabolism2014
- Author(s)
  Osawa T et al.
- Organizer
  Keystone Symposia
- Place of Presentation
  Whistler (Canada)
- Data Source
  KAKENHI-PUBLICLY-25134706
[Presentation] 低酸素・低栄養の腫瘍微小環境におけるエネルギー代謝の解明2014
- Author(s)
  大澤
- Organizer
  がん若手ワークショップ
- Place of Presentation
  蓼科
- Year and Date
  2014-09-03
- Data Source
  KAKENHI-PROJECT-26710005
[Presentation] Histone demethylases regulate tumor angiogenesis and metabolism2014
- Author(s)
  Osawa et al
- Organizer
  第１８回国際血管生物学会
- Place of Presentation
  京都
- Year and Date
  2014-04-14
- Data Source
  KAKENHI-PROJECT-26710005
[Presentation] 低酸素・低栄養が癌悪性化を誘導する分子機構とその治療への応用2013
- Author(s)
  大澤毅ら
- Organizer
  第７２回日本癌学会学術総会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PUBLICLY-24116509
[Presentation] 低酸素・低栄養の腫瘍微小環境が脂質分解を促進し癌悪性化に寄与する2013
- Author(s)
  大澤毅ら
- Organizer
  第１１回がんとハイポキシア研究会
- Place of Presentation
  仙台
- Invited
- Data Source
  KAKENHI-PUBLICLY-25134706
[Presentation] 低酸素・低栄養に誘導されるヒストン脱メチル化酵素が腫瘍血管新生と癌代謝を制御する2013
- Author(s)
  大澤毅
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜、神奈川県
- Data Source
  KAKENHI-PROJECT-23701047
[Presentation] 低酸素・低栄養の腫瘍微小環境と癌代謝2013
- Author(s)
  大澤毅ら
- Organizer
  第１回がんと代謝研究会
- Place of Presentation
  鶴岡
- Data Source
  KAKENHI-PUBLICLY-25134706
[Presentation] 低酸素・低栄養に誘導されるヒストン脱メチル化酵素が腫瘍血管新生と癌代謝を制御する2013
- Author(s)
  大澤毅ら
- Organizer
  第７２回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PUBLICLY-25134706
[Presentation] 低酸素・低栄養が癌悪性化を誘導する分子機構とその治療への応用2013
- Author(s)
  大澤毅ら
- Organizer
  第７２回日本癌学会学術総会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-23701047
[Presentation] 低酸素・低栄養に誘導されるヒストン脱メチル化酵素が腫瘍血管新生と癌代謝を制御する2013
- Author(s)
  大澤毅ら
- Organizer
  第７２回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23701047
[Presentation] Histone demethylases expressed under hypoxia and nutrient starvation regulate tumor growth by modulating tumor angiogenesis and metabolism, Poster Presentation2013
- Author(s)
  Osawa T
- Organizer
  European Cancer Congress 2013
- Place of Presentation
  Amsterdam, Netherlands
- Data Source
  KAKENHI-PROJECT-23701047
[Presentation] 低酸素・低栄養の腫瘍微小環境と癌代謝2013
- Author(s)
  大澤毅ら
- Organizer
  第１回がんと代謝研究会
- Place of Presentation
  鶴岡
- Data Source
  KAKENHI-PUBLICLY-24116509
[Presentation] 低酸素・低栄養が癌悪性化を誘導する分子機構とその治療への応用2013
- Author(s)
  大澤毅ら
- Organizer
  第７２回日本癌学会学術総会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PUBLICLY-25134706
[Presentation] 低酸素・低栄養の腫瘍微小環境が脂質分解を促進し癌悪性化に寄与する2013
- Author(s)
  大澤毅ら
- Organizer
  第１１回がんとハイポキシア研究会
- Place of Presentation
  仙台
- Invited
- Data Source
  KAKENHI-PROJECT-23701047
[Presentation] 低酸素・低栄養が癌悪性化を誘導する分子機構とその治療への応用2013
- Author(s)
  大澤毅
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜、神奈川県
- Data Source
  KAKENHI-PROJECT-23701047
[Presentation] Histone demethylases expressed under hypoxia and nutrient starvation regulate tumor growth by modulating tumor angiogenesis and metabolism2013
- Author(s)
  Osawa T et al.
- Organizer
  European Cancer Congress 2013
- Place of Presentation
  Amsterdam (Netherlands)
- Data Source
  KAKENHI-PUBLICLY-25134706
[Presentation] 低酸素・低栄養の腫瘍微小環境と癌代謝2013
- Author(s)
  大澤毅ら
- Organizer
  第１回がんと代謝研究会
- Place of Presentation
  鶴岡
- Data Source
  KAKENHI-PROJECT-23701047
[Presentation] Histone demethylases expressed under hypoxia and nutrient starvation regulate tumor growth by modulating tumor angiogenesis and metabolism2013
- Author(s)
  Osawa T et al.
- Organizer
  European Cancer Congress 2013
- Place of Presentation
  Amsterdam (Netherlands)
- Data Source
  KAKENHI-PROJECT-23701047
[Presentation] 低酸素・低栄養に誘導されるヒストン脱メチル化酵素が腫瘍血管新生と癌代謝を制御する2013
- Author(s)
  大澤毅ら
- Organizer
  第７２回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PUBLICLY-24116509
[Presentation] Histone demethylases expressed under hypoxia and nutrient starvation regulate tumor growth by modulating tumor angiogenesis and metabolism2013
- Author(s)
  Osawa T et al.
- Organizer
  European Cancer Congress 2013
- Place of Presentation
  Amsterdam (Netherlands)
- Data Source
  KAKENHI-PUBLICLY-24116509
[Presentation] 低酸素・低栄養の腫瘍微小環境が脂質分解を促進し癌悪性化に寄与する2013
- Author(s)
  大澤毅ら
- Organizer
  第１１回がんとハイポキシア研究会
- Place of Presentation
  仙台
- Invited
- Data Source
  KAKENHI-PUBLICLY-24116509
[Presentation] Paradoxically Impaired Development of Atherosclerosis in Hyperlipidemic Down’s syndrome candidate region-1-/- and Apolipoprotein E-/- Double-Knockout Mice2012
- Author(s)
  Osawa T, Toyama K, Nakagawa S, Miura M, Suehiro J, Tanaka T, Aburatani H, Kodama T, and Minami T
- Organizer
  The International Vascular Biology Meeting
- Place of Presentation
  Wiesbaden (Germany)
- Year and Date
  2012-06-02
- Data Source
  KAKENHI-PUBLICLY-24116509
[Presentation] 低酸素・低栄養に誘導されるヒストン修飾酵素が血管新生を介して癌の増殖を制御する2012
- Author(s)
  大澤毅, 土田里香、村松昌、王峰、島村徹平、宮野悟、南敬、児玉龍彦、澁谷正史
- Organizer
  第7１回日本癌学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PUBLICLY-24116509
[Presentation] Inhibition of histone demethylase JHDM2A expressed under hypoxia and nutrient starvation suppresses tumor growth and enhances anti-angiogenic therapy2012
- Author(s)
  Osawa T
- Organizer
  Keystone Symposia on Angiogenesis
- Place of Presentation
  Snowbird Utah
- Data Source
  KAKENHI-PROJECT-23701047
[Presentation] Down’s syndrome candidate region-1 mediates corneal opacity via corneal angiogenesis2012
- Author(s)
  Osawa T, Nakagawa S, Toyono T, Toyama K, Miura M, Suehiro J, Tanaka T, Usui T, Amano S, Aburatani H, Kodama T, and Minami T
- Organizer
  The 10th Korea-Japan Joint Symposium on Vascular Viology
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-23701047
[Presentation] Down’s syndrome candidate region-1 mediates corneal opacity via corneal angiogenesis2012
- Author(s)
  Osawa T, Nakagawa S, Toyono T, Toyama K, Miura M, Suehiro J, Tanaka T, Usui T, Amano S, Aburatani H, Kodama T, and Minami T
- Organizer
  The 10th Korea-Japan Joint Symposium on Vascular Biology
- Place of Presentation
  徳島
- Year and Date
  2012-12-05
- Data Source
  KAKENHI-PUBLICLY-24116509
[Presentation] Paradoxically Impaired Development of Atherosclerosis in Hyperlipidemic Down’s syndrome candidate region-1-/- and Apolipoprotein E-/- Double-Knockout Mice2012
- Author(s)
  Osawa T, Toyama K, Nakagawa S, Miura M, Suehiro J, Tanaka T, Aburatani H, Kodama T, and Minami T
- Organizer
  The International Vascular Biology Meeting
- Place of Presentation
  Wiesbaden (Germany)
- Data Source
  KAKENHI-PROJECT-23701047
[Presentation] 低酸素・低栄養に誘導されるヒストン修飾酵素が血管新生を介して癌の増殖を制御する2012
- Author(s)
  大澤毅
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌、北海道
- Data Source
  KAKENHI-PROJECT-23701047
[Presentation] Paradoxically Impaired Development of Atherosclerosis in Hyperlipidemic Down's syndrome candidate E-/region-1-/-and Apolipoprotein Double-Knockout Mice2012
- Author(s)
  Osawa T
- Organizer
  The International Vascular Biology Meeting
- Place of Presentation
  Wiesbaden, Germany
- Data Source
  KAKENHI-PROJECT-23701047
[Presentation] Inhibition of histone demethylase JHDM2A expressed under hypoxia and nutrient starvation suppresses tumor growth and enhances anti-angiogenic therapy2012
- Author(s)
  Osawa T
- Organizer
  Keystone Symposia(招待講演)
- Place of Presentation
  Snowbird Utah, USA
- Data Source
  KAKENHI-PROJECT-23701047
[Presentation] Down's syndrome candidate region-1 mediates corneal opacity via corneal angiogenesis. Oral presentation2012
- Author(s)
  Osawa T
- Organizer
  The 10th Korea-Japan Joint Symposium on Vascular Viology
- Place of Presentation
  Tokushima
- Data Source
  KAKENHI-PROJECT-23701047
[Presentation] 低酸素・低栄養に誘導されるヒストン修飾酵素が血管新生を介して癌の増殖を制御する2012
- Author(s)
  大澤毅, 土田里香、村松昌、王峰、島村徹平、宮野悟、南敬、児玉龍彦、澁谷正史
- Organizer
  第7１回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23701047
[Presentation] 低酸素・低栄養で誘導されるヒストン脱メチル化酵素ＪＨＤＭ２Ａは血管新生を介して癌の進展に寄与する2011
- Author(s)
  大澤毅ら
- Organizer
  日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-23701047
[Presentation] 低酸素・低栄養下で生存する癌細胞を標的とした新規制癌法2011
- Author(s)
  大澤毅ら
- Organizer
  がんとハイポキシア研究会
- Place of Presentation
  学習院大学（東京都）
- Data Source
  KAKENHI-PROJECT-23701047
[Presentation] 低酸素・低栄養で誘導されるヒストン脱メチル化酵素JHDM2Aは血管新生を介して癌の進展に寄与する2011
- Author(s)
  大澤毅
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜、神奈川県
- Data Source
  KAKENHI-PROJECT-23701047
[Presentation] Inhibition of histone demethylase JHDM2A suppresses tumor growth and enhances anti-angiogenic therapy2011
- Author(s)
  Osawa T., et al.
- Organizer
  The 9th Japan-Korea Joint Symposium on Vascular Biology
- Place of Presentation
  Busan, Korea
- Data Source
  KAKENHI-PROJECT-23701047
[Presentation] 低酸素・低栄養下で生存する癌細胞を標的とした新規制癌法2011
- Author(s)
  大澤毅ら
- Organizer
  日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県）
- Data Source
  KAKENHI-PROJECT-23701047
[Presentation] Histone demethylases regulate tumor growth and enhances anti-angiogenic 1st therapy2011
- Author(s)
  Osawa T
- Organizer
  The Asia-Pacific Vascular Biology Meeting
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-23701047
[Presentation] 低酸素・低栄養に抵抗性を持つ癌細胞を標的とした新規制癌法2011
- Author(s)
  大澤毅ら
- Organizer
  東京大学生命科学シンポジウム
- Place of Presentation
  東京大学（東京都）
- Data Source
  KAKENHI-PROJECT-23701047
[Presentation] Inhibition of histone demethylase JHDM2A suppresses tumor growth and 9th enhances anti-angiogenic therapy2011
- Author(s)
  Osawa T
- Organizer
  The Japan-Korea Joint Symposium on Vascular Biology
- Place of Presentation
  Busan, Korea
- Data Source
  KAKENHI-PROJECT-23701047
[Presentation] Targeting cancer cells resistant to hypoxia and nutrient starvation double-deprivation stress as a novel cancer therapy2011
- Author(s)
  Osawa T
- Organizer
  The American Association for Cancer Research 102st Annual Meeting
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PROJECT-23701047
[Presentation] 低酸素・低栄養下で生存する癌細胞を標的とした新規制癌法2011
- Author(s)
  大澤毅
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋、愛知県
- Data Source
  KAKENHI-PROJECT-23701047
[Presentation] 低酸素・低栄養によって誘導されるヒストン脱メチル化酵素JHDM2Aを標的とした新規制癌法2011
- Author(s)
  大澤毅
- Organizer
  がん若手研究者ワークショップ
- Place of Presentation
  アートランド蓼科（長野県）
- Data Source
  KAKENHI-PROJECT-23701047
[Presentation] Histone demethylases regulate tumor growth and enhances anti-angiogenic therapy2011
- Author(s)
  Osawa T., et al.
- Organizer
  The 1st Asia-Pacific Vascular Biology Meeting(招待講演)
- Place of Presentation
  東京駅カンファレンス（東京都）
- Data Source
  KAKENHI-PROJECT-23701047
[Presentation] 腫瘍微小環境におけるエピゲノム制御を介したオンコメタボライトの解析
- Author(s)
  大澤ら
- Organizer
  第３７回分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PUBLICLY-26116711
[Presentation] 低酸素・低栄養の腫瘍微小環境において癌細胞はエピゲノム制御を介して脂質代謝を誘導する
- Author(s)
  大澤ら
- Organizer
  第７３回日本癌学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PUBLICLY-26116711
[Presentation] Cancer cells utilize lipid metabolism under hypoxic and nutrient starved tumor microenvironment
- Author(s)
  大澤ら
- Organizer
  第１回血管生物医学若手研究会
- Place of Presentation
  東京大学
- Year and Date
  2015-02-06 – 2015-02-07
- Invited
- Data Source
  KAKENHI-PUBLICLY-26116711
[Presentation] 低酸素・低栄養の腫瘍微小環境におけるエネルギー代謝の解明
- Author(s)
  大澤ら
- Organizer
  癌若手ワークショップ
- Place of Presentation
  蓼科グランドホテル
- Year and Date
  2014-09-03 – 2014-09-06
- Data Source
  KAKENHI-PUBLICLY-26116711
[Presentation] 腫瘍微小環境における代謝とシステムバイオロジー
- Author(s)
  大澤ら
- Organizer
  第８７回日本生化学会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-15 – 2014-10-18
- Invited
- Data Source
  KAKENHI-PUBLICLY-26116711
[Presentation] Histone demethylases regulate tumor angiogenesis and metabolism
- Author(s)
  Osawa et al.
- Organizer
  第18回国際血管生物学会
- Place of Presentation
  みやこメッセ京都
- Year and Date
  2014-04-14 – 2014-04-17
- Data Source
  KAKENHI-PUBLICLY-26116711
[Presentation] 腫瘍微小環境に起因するエピゲノム因子とncRNAの腫瘍増殖機構とsiRNAを用いた増殖抑制
- Author(s)
  大澤ら
- Organizer
  第６回日本RNAi研究会
- Place of Presentation
  グランドプリンスホテル広島
- Year and Date
  2014-08-28 – 2014-08-30
- Invited
- Data Source
  KAKENHI-PUBLICLY-26116711

1. 内田広夫 (40275699)

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Osawa Tsuyoshi 大澤 毅

OSAWA Tsuyoshi 大澤 毅

Research Projects

Research Products

Co-Researchers

pH関連代謝物のカタログ化および計測技術開発Principal Investigator

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新規神経芽腫マーカー（CTN/VLA）の有効性（診断率・悪性度予測）検証と病態解明

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婦人科がん患者のQOLや治療成績に関わる食事と腸内細菌叢・代謝物の探索的研究

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自己由来分子による炎症・免疫応答系の調節機構の解明と関連病態制御の基盤構築

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Exploring cancer specific organelle nutrient sensorsPrincipal Investigator

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Improvement and Validation of a Discriminant Model for Amplification of the Neuroblastoma MYC Gene by Tyrosine Metabolite Markers

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腎芽腫メタボローム解析（尿/組織）による診断マーカーとオンコメタボライト探索

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横紋筋肉腫メタボローム解析（尿/組織）による診断マーカーとオンコメタボライト探索

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腎芽腫患児の代謝物網羅解析によるバイオマーカーの探索と創薬への挑戦

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Elucidation of metabolointeractome in tumor microenvironmentsPrincipal Investigator

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がん微小環境における代謝適応フィードバックシステムの解明Principal Investigator

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Elucidation of amino acid adaptive sensor in cancer cellsPrincipal Investigator

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Tolerance of cancer cells against amino acids deprivation in tumor microenvironmentsPrincipal Investigator

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Osawa Tsuyoshi 大澤毅

OSAWA Tsuyoshi 大澤毅

[Book] マルチオミクス研究のすすめ ~ マルチオミクスデータ駆動時代の疾患研究2023